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{{f5samples
{{f5samples
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Line 35: Line 41:
|fonse_treatment_closure=
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|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/oral%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aCa9-22.CNhs10752.10434-106E2.hg38.nobarcode.bam
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|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10434
|name=oral squamous cell carcinoma cell line:Ca9-22
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Line 42: Line 60:
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Line 54: Line 75:
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Line 69: Line 91:
|sample_ethnicity=J
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|sample_experimental_condition=
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;4.70882860811236e-234!GO:0005737;cytoplasm;2.11531673636828e-186!GO:0043226;organelle;1.6052151288926e-182!GO:0043229;intracellular organelle;4.67928689756379e-182!GO:0043227;membrane-bound organelle;8.62243570390258e-173!GO:0043231;intracellular membrane-bound organelle;8.62243570390258e-173!GO:0044422;organelle part;1.31938431090607e-142!GO:0044446;intracellular organelle part;1.04652926082735e-140!GO:0044444;cytoplasmic part;7.73215690301236e-124!GO:0032991;macromolecular complex;8.58567969416496e-96!GO:0044237;cellular metabolic process;1.23788888875658e-81!GO:0044238;primary metabolic process;7.0378733226716e-81!GO:0030529;ribonucleoprotein complex;1.92780710840861e-76!GO:0003723;RNA binding;6.23680784902646e-73!GO:0043170;macromolecule metabolic process;1.61411714220714e-72!GO:0043233;organelle lumen;1.3587117616728e-71!GO:0031974;membrane-enclosed lumen;1.3587117616728e-71!GO:0044428;nuclear part;2.78121998585943e-69!GO:0005634;nucleus;2.64811113106373e-68!GO:0005515;protein binding;3.98214692685283e-68!GO:0005739;mitochondrion;1.14648330410711e-56!GO:0019538;protein metabolic process;2.572382933795e-53!GO:0043234;protein complex;1.79913490265311e-50!GO:0031090;organelle membrane;1.44966695909383e-49!GO:0044267;cellular protein metabolic process;9.51406096152581e-48!GO:0044260;cellular macromolecule metabolic process;2.52575760283571e-47!GO:0005840;ribosome;5.50123682088667e-47!GO:0006396;RNA processing;6.4556795957754e-47!GO:0006412;translation;9.17981381179718e-47!GO:0031981;nuclear lumen;2.14741275879526e-44!GO:0016043;cellular component organization and biogenesis;2.77936497014028e-43!GO:0043283;biopolymer metabolic process;6.26482037172681e-42!GO:0033036;macromolecule localization;9.11623869792586e-42!GO:0015031;protein transport;1.7874993551172e-41!GO:0009058;biosynthetic process;3.56497308360694e-41!GO:0003735;structural constituent of ribosome;1.53716294112852e-40!GO:0005829;cytosol;2.48635178002059e-39!GO:0044249;cellular biosynthetic process;4.66530985343288e-39!GO:0008104;protein localization;1.41839320520969e-37!GO:0045184;establishment of protein localization;2.31330227577023e-37!GO:0016071;mRNA metabolic process;4.83599287360147e-37!GO:0043228;non-membrane-bound organelle;3.11683949120922e-36!GO:0043232;intracellular non-membrane-bound organelle;3.11683949120922e-36!GO:0033279;ribosomal subunit;2.41469929187565e-35!GO:0009059;macromolecule biosynthetic process;6.31795657846126e-35!GO:0044429;mitochondrial part;8.12566984181122e-35!GO:0010467;gene expression;1.61674908981112e-33!GO:0008380;RNA splicing;2.94041546276311e-32!GO:0031967;organelle envelope;3.49770651414081e-32!GO:0006397;mRNA processing;6.60832824447627e-32!GO:0031975;envelope;7.3461439949778e-32!GO:0046907;intracellular transport;1.25020842330962e-31!GO:0065003;macromolecular complex assembly;2.19476987805391e-31!GO:0006996;organelle organization and biogenesis;2.93673073127908e-30!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.23889597318147e-30!GO:0005654;nucleoplasm;3.01587619677097e-28!GO:0006886;intracellular protein transport;7.53850076269482e-28!GO:0000166;nucleotide binding;9.9829690820127e-28!GO:0022607;cellular component assembly;1.8540190314896e-27!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.58075313981147e-27!GO:0006259;DNA metabolic process;2.02417212396327e-26!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.14778452277206e-26!GO:0012505;endomembrane system;3.96335391367443e-24!GO:0044451;nucleoplasm part;5.74570147545177e-23!GO:0005681;spliceosome;1.70698354412385e-22!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;5.60949336548815e-22!GO:0016462;pyrophosphatase activity;5.8715787761364e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;5.8856323768526e-22!GO:0044445;cytosolic part;1.36645990118588e-21!GO:0016874;ligase activity;2.05686519274755e-21!GO:0005783;endoplasmic reticulum;2.95844482594005e-21!GO:0017111;nucleoside-triphosphatase activity;3.61554883940192e-21!GO:0051641;cellular localization;1.63902868701832e-20!GO:0051649;establishment of cellular localization;1.64316804142718e-20!GO:0006512;ubiquitin cycle;3.81805911755423e-20!GO:0007049;cell cycle;5.27175618967651e-20!GO:0005740;mitochondrial envelope;6.51643592563646e-20!GO:0006457;protein folding;1.62251217239441e-19!GO:0031966;mitochondrial membrane;2.23186443569978e-19!GO:0015935;small ribosomal subunit;3.01379085173237e-19!GO:0006119;oxidative phosphorylation;3.18578714114067e-19!GO:0032553;ribonucleotide binding;4.07236445799339e-19!GO:0032555;purine ribonucleotide binding;4.07236445799339e-19!GO:0017076;purine nucleotide binding;4.94917998662777e-19!GO:0019866;organelle inner membrane;6.09100379010191e-19!GO:0043412;biopolymer modification;7.39771450089639e-19!GO:0003676;nucleic acid binding;7.99370911099133e-19!GO:0043285;biopolymer catabolic process;2.80515993401791e-18!GO:0044265;cellular macromolecule catabolic process;3.19438017970786e-18!GO:0044432;endoplasmic reticulum part;4.0095547558436e-18!GO:0031980;mitochondrial lumen;5.37843784007894e-18!GO:0005759;mitochondrial matrix;5.37843784007894e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;6.60630467292937e-18!GO:0005730;nucleolus;7.38665268264621e-18!GO:0019941;modification-dependent protein catabolic process;1.29638155875145e-17!GO:0043632;modification-dependent macromolecule catabolic process;1.29638155875145e-17!GO:0044257;cellular protein catabolic process;1.4531877367013e-17!GO:0006511;ubiquitin-dependent protein catabolic process;2.19064946371886e-17!GO:0048770;pigment granule;2.89107446141363e-17!GO:0042470;melanosome;2.89107446141363e-17!GO:0005743;mitochondrial inner membrane;3.60166679236126e-17!GO:0008134;transcription factor binding;3.79770130121763e-17!GO:0005524;ATP binding;4.52071030479138e-17!GO:0015934;large ribosomal subunit;4.6089024517883e-17!GO:0032559;adenyl ribonucleotide binding;7.83508378676768e-17!GO:0022618;protein-RNA complex assembly;1.25869308252438e-16!GO:0030554;adenyl nucleotide binding;1.40276027928148e-16!GO:0009057;macromolecule catabolic process;2.0595364509858e-16!GO:0006464;protein modification process;2.80463130842153e-16!GO:0008135;translation factor activity, nucleic acid binding;8.01752120859723e-16!GO:0005794;Golgi apparatus;8.72593216866337e-16!GO:0030163;protein catabolic process;1.01199021252479e-15!GO:0006974;response to DNA damage stimulus;1.6399168350993e-15!GO:0044248;cellular catabolic process;5.15904953896628e-15!GO:0044455;mitochondrial membrane part;5.7079485778682e-15!GO:0043687;post-translational protein modification;5.75979875716466e-15!GO:0000502;proteasome complex (sensu Eukaryota);6.26546127892694e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.68801823027315e-14!GO:0006605;protein targeting;1.93738459872152e-14!GO:0022402;cell cycle process;3.2000707892674e-14!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.63459353615765e-14!GO:0051082;unfolded protein binding;5.13158147629357e-14!GO:0005789;endoplasmic reticulum membrane;1.18366924133921e-13!GO:0016192;vesicle-mediated transport;1.58606359521263e-13!GO:0051276;chromosome organization and biogenesis;1.788254918851e-13!GO:0016070;RNA metabolic process;2.0059896059895e-13!GO:0016887;ATPase activity;2.50086742312175e-13!GO:0005761;mitochondrial ribosome;4.97776029190596e-13!GO:0000313;organellar ribosome;4.97776029190596e-13!GO:0000278;mitotic cell cycle;7.37398475919233e-13!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.28335420663307e-12!GO:0006281;DNA repair;1.28335420663307e-12!GO:0005635;nuclear envelope;1.58500907824391e-12!GO:0048193;Golgi vesicle transport;1.58500907824391e-12!GO:0042623;ATPase activity, coupled;1.79848805550786e-12!GO:0005746;mitochondrial respiratory chain;1.81250848367778e-12!GO:0051186;cofactor metabolic process;2.06483265240898e-12!GO:0006325;establishment and/or maintenance of chromatin architecture;2.48296371685678e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.91318128153254e-12!GO:0003743;translation initiation factor activity;3.61597223185481e-12!GO:0031965;nuclear membrane;4.2866149975106e-12!GO:0005694;chromosome;6.67888723343894e-12!GO:0006323;DNA packaging;9.45454538432494e-12!GO:0000398;nuclear mRNA splicing, via spliceosome;1.19539773225115e-11!GO:0000375;RNA splicing, via transesterification reactions;1.19539773225115e-11!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.19539773225115e-11!GO:0050136;NADH dehydrogenase (quinone) activity;1.19539773225115e-11!GO:0003954;NADH dehydrogenase activity;1.19539773225115e-11!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.19539773225115e-11!GO:0042254;ribosome biogenesis and assembly;1.40172291226101e-11!GO:0009719;response to endogenous stimulus;1.51750445916599e-11!GO:0006399;tRNA metabolic process;2.50676782404065e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.17070364348653e-11!GO:0004386;helicase activity;3.51817424380526e-11!GO:0016604;nuclear body;3.86154703262794e-11!GO:0006366;transcription from RNA polymerase II promoter;6.77398545873822e-11!GO:0044453;nuclear membrane part;7.55557002618462e-11!GO:0006732;coenzyme metabolic process;1.31794982487851e-10!GO:0012501;programmed cell death;1.36757606594765e-10!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.44208707768314e-10!GO:0008639;small protein conjugating enzyme activity;2.25731242825556e-10!GO:0006413;translational initiation;2.27817547868097e-10!GO:0009055;electron carrier activity;2.31345916922568e-10!GO:0006915;apoptosis;2.65356265393937e-10!GO:0044427;chromosomal part;3.29124487683237e-10!GO:0006913;nucleocytoplasmic transport;3.61575215646178e-10!GO:0004842;ubiquitin-protein ligase activity;4.08046632505917e-10!GO:0019787;small conjugating protein ligase activity;4.13073486275608e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.21156901261285e-10!GO:0003712;transcription cofactor activity;5.27101786717512e-10!GO:0042775;organelle ATP synthesis coupled electron transport;5.44761630854117e-10!GO:0042773;ATP synthesis coupled electron transport;5.44761630854117e-10!GO:0051169;nuclear transport;6.71139709121848e-10!GO:0008026;ATP-dependent helicase activity;8.16108548835366e-10!GO:0030964;NADH dehydrogenase complex (quinone);8.88193027778327e-10!GO:0045271;respiratory chain complex I;8.88193027778327e-10!GO:0005747;mitochondrial respiratory chain complex I;8.88193027778327e-10!GO:0006461;protein complex assembly;1.07439986350639e-09!GO:0008565;protein transporter activity;1.31048517239715e-09!GO:0008219;cell death;1.38625858326386e-09!GO:0016265;death;1.38625858326386e-09!GO:0005768;endosome;1.5008716759856e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.971511184976e-09!GO:0004812;aminoacyl-tRNA ligase activity;1.971511184976e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.971511184976e-09!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.97234263884013e-09!GO:0016881;acid-amino acid ligase activity;2.14394037420248e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.16889236928054e-09!GO:0016607;nuclear speck;3.48758454212184e-09!GO:0009056;catabolic process;3.51202120285592e-09!GO:0006446;regulation of translational initiation;4.8153650744165e-09!GO:0005643;nuclear pore;4.89224938911652e-09!GO:0043038;amino acid activation;4.92340329666227e-09!GO:0006418;tRNA aminoacylation for protein translation;4.92340329666227e-09!GO:0043039;tRNA aminoacylation;4.92340329666227e-09!GO:0048475;coated membrane;5.11595776157617e-09!GO:0030117;membrane coat;5.11595776157617e-09!GO:0051188;cofactor biosynthetic process;5.54994407768804e-09!GO:0000087;M phase of mitotic cell cycle;6.57521406203801e-09!GO:0006403;RNA localization;7.3250865908552e-09!GO:0050657;nucleic acid transport;7.39133289013893e-09!GO:0051236;establishment of RNA localization;7.39133289013893e-09!GO:0050658;RNA transport;7.39133289013893e-09!GO:0000074;regulation of progression through cell cycle;9.7208609049803e-09!GO:0051726;regulation of cell cycle;1.12037691049283e-08!GO:0016787;hydrolase activity;1.29586637186629e-08!GO:0007067;mitosis;1.36608691444513e-08!GO:0015986;ATP synthesis coupled proton transport;1.41382640057734e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.41382640057734e-08!GO:0022403;cell cycle phase;1.94317643266794e-08!GO:0009259;ribonucleotide metabolic process;2.05603159451294e-08!GO:0005793;ER-Golgi intermediate compartment;2.09219010894819e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.99124823084601e-08!GO:0006163;purine nucleotide metabolic process;5.28570208964308e-08!GO:0006260;DNA replication;5.34944396785664e-08!GO:0065004;protein-DNA complex assembly;5.47200665499629e-08!GO:0000785;chromatin;6.42002575088079e-08!GO:0019829;cation-transporting ATPase activity;6.61343074769741e-08!GO:0006164;purine nucleotide biosynthetic process;8.3383911524748e-08!GO:0006333;chromatin assembly or disassembly;9.02094368698242e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;9.14442435881682e-08!GO:0009260;ribonucleotide biosynthetic process;9.46754517862457e-08!GO:0016568;chromatin modification;9.71048594956153e-08!GO:0009108;coenzyme biosynthetic process;1.10221805890774e-07!GO:0009150;purine ribonucleotide metabolic process;1.28355994845666e-07!GO:0006793;phosphorus metabolic process;1.70082117608826e-07!GO:0006796;phosphate metabolic process;1.70082117608826e-07!GO:0009152;purine ribonucleotide biosynthetic process;1.97349801848139e-07!GO:0006754;ATP biosynthetic process;2.03411680715759e-07!GO:0006753;nucleoside phosphate metabolic process;2.03411680715759e-07!GO:0032446;protein modification by small protein conjugation;2.0845265402427e-07!GO:0065002;intracellular protein transport across a membrane;2.16533526402948e-07!GO:0005667;transcription factor complex;2.23199100691835e-07!GO:0017038;protein import;2.39777197526984e-07!GO:0016567;protein ubiquitination;2.61788276019844e-07!GO:0051301;cell division;2.71267262272727e-07!GO:0030120;vesicle coat;2.86834313978258e-07!GO:0030662;coated vesicle membrane;2.86834313978258e-07!GO:0006888;ER to Golgi vesicle-mediated transport;3.35054894511593e-07!GO:0015078;hydrogen ion transmembrane transporter activity;3.75710773909522e-07!GO:0046930;pore complex;4.08696212600933e-07!GO:0016740;transferase activity;4.33035498110973e-07!GO:0006364;rRNA processing;4.77416425473804e-07!GO:0006752;group transfer coenzyme metabolic process;5.10080822684341e-07!GO:0051028;mRNA transport;5.54721836401868e-07!GO:0016469;proton-transporting two-sector ATPase complex;5.70008971681972e-07!GO:0016072;rRNA metabolic process;6.42831178880622e-07!GO:0046034;ATP metabolic process;6.61547325764661e-07!GO:0016563;transcription activator activity;6.68932889423598e-07!GO:0048523;negative regulation of cellular process;6.73152044253085e-07!GO:0044431;Golgi apparatus part;7.39865412460893e-07!GO:0003924;GTPase activity;1.1410045429941e-06!GO:0044440;endosomal part;1.14853302257382e-06!GO:0010008;endosome membrane;1.14853302257382e-06!GO:0009141;nucleoside triphosphate metabolic process;1.22550268296921e-06!GO:0015630;microtubule cytoskeleton;1.25104886194741e-06!GO:0008654;phospholipid biosynthetic process;1.28212916286684e-06!GO:0051246;regulation of protein metabolic process;1.45230902993416e-06!GO:0043566;structure-specific DNA binding;1.45230902993416e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.62144003534117e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.62144003534117e-06!GO:0000151;ubiquitin ligase complex;1.65415209570623e-06!GO:0000279;M phase;1.95035660585781e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.01965758218918e-06!GO:0009060;aerobic respiration;2.0876963466978e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.19001443492716e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.19001443492716e-06!GO:0009199;ribonucleoside triphosphate metabolic process;2.49095155709787e-06!GO:0045786;negative regulation of progression through cell cycle;2.49943528819361e-06!GO:0007005;mitochondrion organization and biogenesis;2.76689888883932e-06!GO:0016310;phosphorylation;3.33925803369815e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.3578633171025e-06!GO:0009144;purine nucleoside triphosphate metabolic process;3.3578633171025e-06!GO:0045259;proton-transporting ATP synthase complex;3.4853418823707e-06!GO:0043067;regulation of programmed cell death;3.68754722414873e-06!GO:0042981;regulation of apoptosis;4.29961780266047e-06!GO:0003713;transcription coactivator activity;4.81235398958045e-06!GO:0005813;centrosome;5.1464655741153e-06!GO:0031324;negative regulation of cellular metabolic process;5.88074118129338e-06!GO:0005798;Golgi-associated vesicle;5.88074118129338e-06!GO:0005788;endoplasmic reticulum lumen;6.03553064763506e-06!GO:0043623;cellular protein complex assembly;6.10316575269235e-06!GO:0005839;proteasome core complex (sensu Eukaryota);7.42428493533035e-06!GO:0003697;single-stranded DNA binding;8.17671282596139e-06!GO:0003724;RNA helicase activity;8.82150054417785e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.108471168186e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.24031744038146e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.24031744038146e-05!GO:0048519;negative regulation of biological process;1.35194304041878e-05!GO:0005770;late endosome;1.37623908722959e-05!GO:0000245;spliceosome assembly;1.64110917302527e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.64583958837947e-05!GO:0006613;cotranslational protein targeting to membrane;1.65656268045989e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.69113720041181e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.78902347462542e-05!GO:0031988;membrane-bound vesicle;1.79540921554446e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.82568440585423e-05!GO:0051427;hormone receptor binding;1.87558868200966e-05!GO:0005815;microtubule organizing center;2.05359587835473e-05!GO:0016779;nucleotidyltransferase activity;2.21690823596586e-05!GO:0009117;nucleotide metabolic process;2.25368507335745e-05!GO:0045333;cellular respiration;2.37452287951634e-05!GO:0006099;tricarboxylic acid cycle;2.58899400735272e-05!GO:0046356;acetyl-CoA catabolic process;2.58899400735272e-05!GO:0004298;threonine endopeptidase activity;2.87962177546207e-05!GO:0051168;nuclear export;2.91075730982758e-05!GO:0030532;small nuclear ribonucleoprotein complex;3.13945800530885e-05!GO:0016023;cytoplasmic membrane-bound vesicle;3.29769140333504e-05!GO:0006606;protein import into nucleus;3.45027089313133e-05!GO:0006084;acetyl-CoA metabolic process;3.71374058209861e-05!GO:0035257;nuclear hormone receptor binding;3.94519451502718e-05!GO:0000139;Golgi membrane;4.05237980185317e-05!GO:0031497;chromatin assembly;4.19458183061928e-05!GO:0006334;nucleosome assembly;4.39850759689289e-05!GO:0005769;early endosome;4.89936187087342e-05!GO:0016564;transcription repressor activity;5.05867954273345e-05!GO:0019899;enzyme binding;5.09375810522095e-05!GO:0048471;perinuclear region of cytoplasm;5.67101472325436e-05!GO:0005773;vacuole;5.75088284621075e-05!GO:0051170;nuclear import;6.16658801890998e-05!GO:0030118;clathrin coat;6.36754482007758e-05!GO:0009892;negative regulation of metabolic process;6.41965935917265e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.59118747346227e-05!GO:0051329;interphase of mitotic cell cycle;6.68044556739569e-05!GO:0005525;GTP binding;6.86450429058607e-05!GO:0042802;identical protein binding;7.24276160731445e-05!GO:0016491;oxidoreductase activity;8.23059792418116e-05!GO:0031252;leading edge;9.38647146815416e-05!GO:0016853;isomerase activity;9.50480313487469e-05!GO:0007264;small GTPase mediated signal transduction;0.000103797206435565!GO:0031982;vesicle;0.000106573268939174!GO:0005819;spindle;0.000108754745635193!GO:0003690;double-stranded DNA binding;0.000112759519146749!GO:0043021;ribonucleoprotein binding;0.000120452425778859!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000124590994554283!GO:0007243;protein kinase cascade;0.000129919100518195!GO:0006612;protein targeting to membrane;0.000133995195541499!GO:0050794;regulation of cellular process;0.000135493607542622!GO:0005762;mitochondrial large ribosomal subunit;0.000138553426260545!GO:0000315;organellar large ribosomal subunit;0.000138553426260545!GO:0030119;AP-type membrane coat adaptor complex;0.000143678289089287!GO:0033116;ER-Golgi intermediate compartment membrane;0.000149069316674632!GO:0019843;rRNA binding;0.000177677412326691!GO:0045454;cell redox homeostasis;0.000178480180191123!GO:0030867;rough endoplasmic reticulum membrane;0.000178672447539529!GO:0031410;cytoplasmic vesicle;0.000190017044939069!GO:0043069;negative regulation of programmed cell death;0.000193255383844133!GO:0009109;coenzyme catabolic process;0.000193739889403333!GO:0000323;lytic vacuole;0.00020329414290351!GO:0005764;lysosome;0.00020329414290351!GO:0003729;mRNA binding;0.000203490710521173!GO:0003899;DNA-directed RNA polymerase activity;0.000210931563371547!GO:0046467;membrane lipid biosynthetic process;0.000212234754047514!GO:0015631;tubulin binding;0.000225846537913244!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000230164910736127!GO:0015399;primary active transmembrane transporter activity;0.000230164910736127!GO:0008250;oligosaccharyl transferase complex;0.000245644134037382!GO:0006402;mRNA catabolic process;0.000249529370565936!GO:0030131;clathrin adaptor complex;0.000256318496632486!GO:0005048;signal sequence binding;0.000265069665832653!GO:0008186;RNA-dependent ATPase activity;0.000269821041086266!GO:0004576;oligosaccharyl transferase activity;0.000273082867526419!GO:0016481;negative regulation of transcription;0.000282858713334341!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000306048383103089!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000364432131135497!GO:0004674;protein serine/threonine kinase activity;0.00039009794862106!GO:0043066;negative regulation of apoptosis;0.000393925013000916!GO:0008610;lipid biosynthetic process;0.00039812743103306!GO:0016197;endosome transport;0.000399738167979536!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000408723926083314!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000419683756182483!GO:0000314;organellar small ribosomal subunit;0.000432826768492804!GO:0005763;mitochondrial small ribosomal subunit;0.000432826768492804!GO:0051325;interphase;0.000436957541872572!GO:0006261;DNA-dependent DNA replication;0.000443756223149444!GO:0048522;positive regulation of cellular process;0.000443756223149444!GO:0051187;cofactor catabolic process;0.000483909574660705!GO:0008033;tRNA processing;0.000500304145212341!GO:0016859;cis-trans isomerase activity;0.000505178875050207!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000521669938953416!GO:0006916;anti-apoptosis;0.000525214036662205!GO:0006091;generation of precursor metabolites and energy;0.000556161716737681!GO:0046489;phosphoinositide biosynthetic process;0.000630531628457852!GO:0045893;positive regulation of transcription, DNA-dependent;0.000632318975831375!GO:0007051;spindle organization and biogenesis;0.00064576100543946!GO:0019752;carboxylic acid metabolic process;0.000659243692027668!GO:0065009;regulation of a molecular function;0.000702823799506528!GO:0051789;response to protein stimulus;0.000704248428514927!GO:0006986;response to unfolded protein;0.000704248428514927!GO:0003714;transcription corepressor activity;0.000749477847626805!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000767385873334698!GO:0006082;organic acid metabolic process;0.000772348372569772!GO:0004004;ATP-dependent RNA helicase activity;0.000794415720717445!GO:0032561;guanyl ribonucleotide binding;0.000814610683886789!GO:0019001;guanyl nucleotide binding;0.000814610683886789!GO:0006401;RNA catabolic process;0.000821897370038548!GO:0030880;RNA polymerase complex;0.000835522775037251!GO:0003682;chromatin binding;0.000868318640002416!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000869146750024393!GO:0046474;glycerophospholipid biosynthetic process;0.000885737686867533!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000914787869273949!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000945853914105247!GO:0051920;peroxiredoxin activity;0.000989100512203822!GO:0031072;heat shock protein binding;0.00108027689675348!GO:0046483;heterocycle metabolic process;0.00110325333539063!GO:0009967;positive regulation of signal transduction;0.00114431758242502!GO:0006352;transcription initiation;0.0012234960319563!GO:0018196;peptidyl-asparagine modification;0.00129458651606748!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00129458651606748!GO:0006520;amino acid metabolic process;0.00143185664759825!GO:0030658;transport vesicle membrane;0.00163184904962661!GO:0044452;nucleolar part;0.00164492378016378!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00164492378016378!GO:0000428;DNA-directed RNA polymerase complex;0.00164492378016378!GO:0051252;regulation of RNA metabolic process;0.00167901204554275!GO:0005885;Arp2/3 protein complex;0.00170290948055626!GO:0043624;cellular protein complex disassembly;0.00173548241708679!GO:0030176;integral to endoplasmic reticulum membrane;0.00175932135409255!GO:0008632;apoptotic program;0.00181691126469858!GO:0019867;outer membrane;0.00190761303242363!GO:0031968;organelle outer membrane;0.00200998250166109!GO:0016251;general RNA polymerase II transcription factor activity;0.00201441716959128!GO:0016363;nuclear matrix;0.00207528834495314!GO:0045941;positive regulation of transcription;0.00220182784799347!GO:0000049;tRNA binding;0.00220182784799347!GO:0050662;coenzyme binding;0.00220711375596718!GO:0006302;double-strand break repair;0.00234084266695014!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00239673581860448!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00239673581860448!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00239673581860448!GO:0006818;hydrogen transport;0.00246141660758479!GO:0030384;phosphoinositide metabolic process;0.00246141660758479!GO:0008017;microtubule binding;0.00248153005680538!GO:0008652;amino acid biosynthetic process;0.00249588467616055!GO:0009112;nucleobase metabolic process;0.00250124002961251!GO:0030132;clathrin coat of coated pit;0.00266462404352097!GO:0043492;ATPase activity, coupled to movement of substances;0.00270209791643923!GO:0015992;proton transport;0.00270209791643923!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00274123314791436!GO:0006650;glycerophospholipid metabolic process;0.00274973985608026!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00283627247741306!GO:0048500;signal recognition particle;0.00284413809708887!GO:0001726;ruffle;0.00290436103819128!GO:0030133;transport vesicle;0.00290548067878363!GO:0006414;translational elongation;0.00290739103589688!GO:0006891;intra-Golgi vesicle-mediated transport;0.00315707112958599!GO:0016791;phosphoric monoester hydrolase activity;0.00347620528918582!GO:0032984;macromolecular complex disassembly;0.00353304731724147!GO:0006405;RNA export from nucleus;0.00353598465207004!GO:0005905;coated pit;0.00365791905745417!GO:0051087;chaperone binding;0.0037361536073781!GO:0000082;G1/S transition of mitotic cell cycle;0.00382573083228667!GO:0008092;cytoskeletal protein binding;0.00382573083228667!GO:0007010;cytoskeleton organization and biogenesis;0.00413768010579193!GO:0005791;rough endoplasmic reticulum;0.00415792288804511!GO:0030036;actin cytoskeleton organization and biogenesis;0.00416783722750841!GO:0000775;chromosome, pericentric region;0.00420481312874318!GO:0012506;vesicle membrane;0.00429187123546444!GO:0048487;beta-tubulin binding;0.0043037597333606!GO:0005741;mitochondrial outer membrane;0.00466026261303458!GO:0030660;Golgi-associated vesicle membrane;0.00467444979290435!GO:0035258;steroid hormone receptor binding;0.00474718524415045!GO:0000786;nucleosome;0.00480345606291634!GO:0030663;COPI coated vesicle membrane;0.00482293854839758!GO:0030126;COPI vesicle coat;0.00482293854839758!GO:0030134;ER to Golgi transport vesicle;0.00484551497349125!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00496144773304729!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00496144773304729!GO:0030659;cytoplasmic vesicle membrane;0.00504760112528678!GO:0015980;energy derivation by oxidation of organic compounds;0.00507100492221325!GO:0007040;lysosome organization and biogenesis;0.0051858673680022!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00520978010070329!GO:0051052;regulation of DNA metabolic process;0.0053021088788765!GO:0003702;RNA polymerase II transcription factor activity;0.00530618197916168!GO:0003711;transcription elongation regulator activity;0.00547493679952052!GO:0005657;replication fork;0.00547692998537034!GO:0043488;regulation of mRNA stability;0.00553964379076021!GO:0043487;regulation of RNA stability;0.00553964379076021!GO:0003684;damaged DNA binding;0.00554068633673478!GO:0043241;protein complex disassembly;0.00566925020521153!GO:0007033;vacuole organization and biogenesis;0.00569726607706507!GO:0045792;negative regulation of cell size;0.00577513320407932!GO:0007242;intracellular signaling cascade;0.00579647250823418!GO:0016044;membrane organization and biogenesis;0.0058269663927717!GO:0022890;inorganic cation transmembrane transporter activity;0.00588730777561724!GO:0006383;transcription from RNA polymerase III promoter;0.0058946020794866!GO:0000075;cell cycle checkpoint;0.00590780313360645!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.00593757470763856!GO:0006626;protein targeting to mitochondrion;0.00594131569975145!GO:0009165;nucleotide biosynthetic process;0.00594131569975145!GO:0006611;protein export from nucleus;0.00625106845209638!GO:0044433;cytoplasmic vesicle part;0.00634257224792231!GO:0006643;membrane lipid metabolic process;0.00637566289838944!GO:0043681;protein import into mitochondrion;0.00642147096928536!GO:0047485;protein N-terminus binding;0.00669560755357982!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00695008299686791!GO:0030032;lamellipodium biogenesis;0.00720177455311018!GO:0000059;protein import into nucleus, docking;0.00722057469727352!GO:0008312;7S RNA binding;0.00728588042707641!GO:0007050;cell cycle arrest;0.00762487981883089!GO:0006839;mitochondrial transport;0.00763512156506607!GO:0008094;DNA-dependent ATPase activity;0.00774780561258305!GO:0045045;secretory pathway;0.00776213890662511!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00784118109220177!GO:0006984;ER-nuclear signaling pathway;0.00784118109220177!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00789008366526346!GO:0045047;protein targeting to ER;0.00789008366526346!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00811953970625651!GO:0022411;cellular component disassembly;0.00812179449687233!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00825581742658104!GO:0008139;nuclear localization sequence binding;0.0082662491488886!GO:0005637;nuclear inner membrane;0.00838964605248932!GO:0043022;ribosome binding;0.00842974414867!GO:0016584;nucleosome positioning;0.00859167872184658!GO:0031625;ubiquitin protein ligase binding;0.00860036892028211!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00874488872963737!GO:0048037;cofactor binding;0.00882549403010312!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00882651761774643!GO:0050790;regulation of catalytic activity;0.00882651761774643!GO:0030137;COPI-coated vesicle;0.00882651761774643!GO:0006607;NLS-bearing substrate import into nucleus;0.00887374246078319!GO:0030308;negative regulation of cell growth;0.00918133132996866!GO:0045892;negative regulation of transcription, DNA-dependent;0.00930947891036655!GO:0008629;induction of apoptosis by intracellular signals;0.00937166419055414!GO:0000776;kinetochore;0.00939486585012588!GO:0006506;GPI anchor biosynthetic process;0.00992481174119587!GO:0005684;U2-dependent spliceosome;0.00994405389511066!GO:0030127;COPII vesicle coat;0.0100096219350961!GO:0012507;ER to Golgi transport vesicle membrane;0.0100096219350961!GO:0006289;nucleotide-excision repair;0.0103773653831408!GO:0008361;regulation of cell size;0.0103836313334325!GO:0006505;GPI anchor metabolic process;0.0104279843590695!GO:0046983;protein dimerization activity;0.0104610723605438!GO:0008022;protein C-terminus binding;0.0104610723605438!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0105315696627069!GO:0004721;phosphoprotein phosphatase activity;0.0107692516633069!GO:0003678;DNA helicase activity;0.0108792376675027!GO:0005774;vacuolar membrane;0.0109512199590931!GO:0030029;actin filament-based process;0.0111972178391964!GO:0030521;androgen receptor signaling pathway;0.0114594743736309!GO:0006595;polyamine metabolic process;0.0115663529000891!GO:0030125;clathrin vesicle coat;0.0115703742769067!GO:0030665;clathrin coated vesicle membrane;0.0115703742769067!GO:0006338;chromatin remodeling;0.0119502211823713!GO:0008097;5S rRNA binding;0.0121950167719599!GO:0031901;early endosome membrane;0.0127665799319361!GO:0007006;mitochondrial membrane organization and biogenesis;0.013122395830527!GO:0046966;thyroid hormone receptor binding;0.0131355013586588!GO:0032508;DNA duplex unwinding;0.0131769043593283!GO:0032392;DNA geometric change;0.0131769043593283!GO:0000118;histone deacetylase complex;0.0131769043593283!GO:0008234;cysteine-type peptidase activity;0.0134467295769956!GO:0016741;transferase activity, transferring one-carbon groups;0.013492246468876!GO:0008168;methyltransferase activity;0.0145958790395537!GO:0000339;RNA cap binding;0.0150433681514167!GO:0045926;negative regulation of growth;0.0154375710535246!GO:0016126;sterol biosynthetic process;0.0159575584367169!GO:0031902;late endosome membrane;0.0159719184187342!GO:0000096;sulfur amino acid metabolic process;0.0160080477326549!GO:0051540;metal cluster binding;0.0162207269147382!GO:0051536;iron-sulfur cluster binding;0.0162207269147382!GO:0005874;microtubule;0.0162220782849805!GO:0009451;RNA modification;0.0163638751311358!GO:0009116;nucleoside metabolic process;0.0163783531673929!GO:0007052;mitotic spindle organization and biogenesis;0.0165197605164656!GO:0007034;vacuolar transport;0.0166223333057663!GO:0016272;prefoldin complex;0.0167705945992509!GO:0051539;4 iron, 4 sulfur cluster binding;0.0171393955183903!GO:0017166;vinculin binding;0.0175970749910269!GO:0005832;chaperonin-containing T-complex;0.0176867663638606!GO:0008637;apoptotic mitochondrial changes;0.0178928122125312!GO:0006497;protein amino acid lipidation;0.0179525058901651!GO:0051338;regulation of transferase activity;0.0187231072648469!GO:0050789;regulation of biological process;0.0188800454692013!GO:0006644;phospholipid metabolic process;0.0189818123964543!GO:0031529;ruffle organization and biogenesis;0.0189970792045301!GO:0032259;methylation;0.0190616317718575!GO:0001558;regulation of cell growth;0.0192915076434344!GO:0006519;amino acid and derivative metabolic process;0.019365386703486!GO:0006144;purine base metabolic process;0.0195207240106135!GO:0043414;biopolymer methylation;0.0196085271564492!GO:0030031;cell projection biogenesis;0.0196376633998173!GO:0003725;double-stranded RNA binding;0.0198733482895978!GO:0007265;Ras protein signal transduction;0.0202790596696784!GO:0016049;cell growth;0.0212343139299001!GO:0022406;membrane docking;0.0215862282771529!GO:0048278;vesicle docking;0.0215862282771529!GO:0051287;NAD binding;0.0221179624545339!GO:0048518;positive regulation of biological process;0.0221565661718287!GO:0019783;small conjugating protein-specific protease activity;0.0224790726995098!GO:0030027;lamellipodium;0.0225277455600295!GO:0006213;pyrimidine nucleoside metabolic process;0.0226885005822545!GO:0031124;mRNA 3'-end processing;0.0227142843656367!GO:0006730;one-carbon compound metabolic process;0.0230603780962415!GO:0006284;base-excision repair;0.0231047100888856!GO:0044437;vacuolar part;0.0231932846554106!GO:0007093;mitotic cell cycle checkpoint;0.0234496324384675!GO:0007021;tubulin folding;0.0234577714466102!GO:0005669;transcription factor TFIID complex;0.0235285181722874!GO:0042393;histone binding;0.0235996848169938!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0235996848169938!GO:0015002;heme-copper terminal oxidase activity;0.0235996848169938!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0235996848169938!GO:0004129;cytochrome-c oxidase activity;0.0235996848169938!GO:0006904;vesicle docking during exocytosis;0.0237574409718565!GO:0006740;NADPH regeneration;0.0241374238795337!GO:0006098;pentose-phosphate shunt;0.0241374238795337!GO:0008180;signalosome;0.0243628090728525!GO:0006400;tRNA modification;0.0243785964591847!GO:0003746;translation elongation factor activity;0.0243785964591847!GO:0004527;exonuclease activity;0.0246046709564573!GO:0033673;negative regulation of kinase activity;0.024778161936486!GO:0006469;negative regulation of protein kinase activity;0.024778161936486!GO:0006672;ceramide metabolic process;0.0248081271859479!GO:0000086;G2/M transition of mitotic cell cycle;0.0249661433348306!GO:0016301;kinase activity;0.0257348133562756!GO:0004518;nuclease activity;0.0257926750374243!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.0259928891396924!GO:0016311;dephosphorylation;0.0261767167096109!GO:0005856;cytoskeleton;0.0262832555303366!GO:0030518;steroid hormone receptor signaling pathway;0.0264192425062402!GO:0005765;lysosomal membrane;0.026469288675028!GO:0019222;regulation of metabolic process;0.0270108163328148!GO:0006892;post-Golgi vesicle-mediated transport;0.0271817609665688!GO:0008538;proteasome activator activity;0.0280792700354075!GO:0051348;negative regulation of transferase activity;0.0282484161735034!GO:0006695;cholesterol biosynthetic process;0.0283632310224929!GO:0006376;mRNA splice site selection;0.0283709807183327!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0283709807183327!GO:0007088;regulation of mitosis;0.0284099313021325!GO:0009081;branched chain family amino acid metabolic process;0.0286695842655007!GO:0006268;DNA unwinding during replication;0.0288089519797917!GO:0030140;trans-Golgi network transport vesicle;0.0292221969013728!GO:0043284;biopolymer biosynthetic process;0.0292730535323712!GO:0045334;clathrin-coated endocytic vesicle;0.029345842403636!GO:0008426;protein kinase C inhibitor activity;0.029345842403636!GO:0031371;ubiquitin conjugating enzyme complex;0.029345842403636!GO:0006564;L-serine biosynthetic process;0.0293850149751161!GO:0051098;regulation of binding;0.0299080293245077!GO:0004843;ubiquitin-specific protease activity;0.0299080293245077!GO:0006415;translational termination;0.0299342970405511!GO:0009303;rRNA transcription;0.0302078775978723!GO:0006979;response to oxidative stress;0.0305570185557451!GO:0046519;sphingoid metabolic process;0.0313910949869509!GO:0005784;translocon complex;0.0314785510416515!GO:0035035;histone acetyltransferase binding;0.0319925985883423!GO:0004177;aminopeptidase activity;0.0326574578994482!GO:0003756;protein disulfide isomerase activity;0.0343781153166277!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0343781153166277!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0343781153166277!GO:0005876;spindle microtubule;0.034437107055585!GO:0006354;RNA elongation;0.0350851456812263!GO:0046822;regulation of nucleocytoplasmic transport;0.035160936705465!GO:0006360;transcription from RNA polymerase I promoter;0.0357429184666695!GO:0050681;androgen receptor binding;0.0358011384015093!GO:0007017;microtubule-based process;0.0358623717180223!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0364831692703903!GO:0006509;membrane protein ectodomain proteolysis;0.0366154833292412!GO:0033619;membrane protein proteolysis;0.0366154833292412!GO:0009119;ribonucleoside metabolic process;0.0374676769905192!GO:0043549;regulation of kinase activity;0.0380932209058193!GO:0016407;acetyltransferase activity;0.0381828471071818!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0384790016774255!GO:0000123;histone acetyltransferase complex;0.038765325923363!GO:0043189;H4/H2A histone acetyltransferase complex;0.0387800426816689!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0396250774694385!GO:0006767;water-soluble vitamin metabolic process;0.0396792015278332!GO:0050811;GABA receptor binding;0.0402837312451191!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0410216694572601!GO:0004860;protein kinase inhibitor activity;0.0410364976648011!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0411045382228678!GO:0040029;regulation of gene expression, epigenetic;0.0413945919876883!GO:0051128;regulation of cellular component organization and biogenesis;0.0418042896055998!GO:0006378;mRNA polyadenylation;0.0419425606951287!GO:0030433;ER-associated protein catabolic process;0.0422970153595187!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0422970153595187!GO:0004221;ubiquitin thiolesterase activity;0.0436758329794383!GO:0031461;cullin-RING ubiquitin ligase complex;0.0438407008888389!GO:0031575;G1/S transition checkpoint;0.0442960210879312!GO:0006950;response to stress;0.0444887806443078!GO:0004300;enoyl-CoA hydratase activity;0.0446038076897504!GO:0048468;cell development;0.044750749736583!GO:0019511;peptidyl-proline hydroxylation;0.044750749736583!GO:0018208;peptidyl-proline modification;0.044750749736583!GO:0019471;4-hydroxyproline metabolic process;0.044750749736583!GO:0018401;peptidyl-proline hydroxylation to 4-hydroxy-L-proline;0.044750749736583!GO:0030911;TPR domain binding;0.045157318922756!GO:0042158;lipoprotein biosynthetic process;0.0454874855036932!GO:0060166;olfactory pit development;0.0455592173496267!GO:0021768;nucleus accumbens development;0.0455592173496267!GO:0002072;optic cup morphogenesis involved in camera-type eye development;0.0455592173496267!GO:0000209;protein polyubiquitination;0.0456307599172417!GO:0017134;fibroblast growth factor binding;0.0465017404068718!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0468662879715997!GO:0006518;peptide metabolic process;0.0471313177030067!GO:0006310;DNA recombination;0.0481338235934159!GO:0051101;regulation of DNA binding;0.0481823860887557!GO:0032200;telomere organization and biogenesis;0.0484779876384973!GO:0000723;telomere maintenance;0.0484779876384973!GO:0007041;lysosomal transport;0.0484798564237881!GO:0022415;viral reproductive process;0.048736566193593!GO:0005862;muscle thin filament tropomyosin;0.0492521971742404!GO:0001952;regulation of cell-matrix adhesion;0.0495723249444362!GO:0042026;protein refolding;0.0496042665684788
|sample_id=10434
|sample_id=10434
|sample_note=machine failed, remainder reloaded, low amount
|sample_note=machine failed, remainder reloaded, low amount
Line 76: Line 99:
|sample_tissue=gum
|sample_tissue=gum
|top_motifs=ZEB1:1.95317290124;TP53:1.87899985738;VSX1,2:1.83436288344;SNAI1..3:1.70116321496;TBX4,5:1.51238018244;ARID5B:1.33416151933;bHLH_family:1.2661924352;FOXQ1:1.25952423126;ELK1,4_GABP{A,B1}:1.19647225519;RBPJ:1.08644945446;XCPE1{core}:1.07980206187;FOXN1:1.03807676507;NRF1:0.988412074244;HIF1A:0.911598524419;ADNP_IRX_SIX_ZHX:0.901402031251;SP1:0.891122633698;NFY{A,B,C}:0.841986715787;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.829166238246;NKX2-1,4:0.827250681066;MYOD1:0.770835171473;CDC5L:0.758694645231;PAX4:0.751360046842;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.747359141157;ZNF143:0.744499425195;EBF1:0.676263783717;SOX17:0.656907932222;FOXP1:0.617825787349;NFE2L2:0.596291614351;HSF1,2:0.591087114518;TEAD1:0.565779326278;ZNF148:0.535346944766;TFAP2{A,C}:0.519971410426;FOSL2:0.4958662932;BACH2:0.438184935829;FOS_FOS{B,L1}_JUN{B,D}:0.428093944828;RFX2..5_RFXANK_RFXAP:0.422301898916;PAX2:0.414229400479;ONECUT1,2:0.396389830138;HOX{A4,D4}:0.347754387237;NKX2-2,8:0.33863014058;HAND1,2:0.333079404767;PITX1..3:0.326846019602;NFE2:0.326842871678;FOX{F1,F2,J1}:0.326161223448;HOX{A6,A7,B6,B7}:0.323317496632;SOX2:0.317134008588;GFI1:0.316315535598;POU1F1:0.299310824277;E2F1..5:0.280702475015;SREBF1,2:0.271113460785;CEBPA,B_DDIT3:0.270405975889;BREu{core}:0.26737032859;IRF7:0.257383283953;NKX3-2:0.248659657508;YY1:0.21717301087;POU2F1..3:0.208423048329;TFDP1:0.189560731942;FOXM1:0.167727731231;LMO2:0.152722878136;LHX3,4:0.152660640238;TEF:0.152130238323;ELF1,2,4:0.147887769014;ZBTB6:0.141820054109;SOX{8,9,10}:0.119922324278;IKZF1:0.107448244173;MAZ:0.0975674906002;MYB:0.0700671773461;PAX1,9:0.0678701911404;ZFP161:0.0603007936365;RFX1:0.0520842885762;CREB1:0.0493222373393;TOPORS:0.0454244773849;PPARG:0.0436069948035;HOXA9_MEIS1:0.0426781225014;OCT4_SOX2{dimer}:0.00397816545412;EP300:-0.00675773063411;TFCP2:-0.00757721423303;FOX{D1,D2}:-0.0188527005761;CUX2:-0.0313860640063;NKX2-3_NKX2-5:-0.0456132429619;ZIC1..3:-0.0486808038038;CDX1,2,4:-0.0583992690315;TFAP2B:-0.0586643600209;CRX:-0.0604389023754;FOXO1,3,4:-0.0661729669086;FOX{I1,J2}:-0.0752199445284;TLX1..3_NFIC{dimer}:-0.0772886273316;AIRE:-0.0870954706459;RORA:-0.101691669513;NR5A1,2:-0.1025502033;MTF1:-0.122667935042;NKX3-1:-0.128891717386;HIC1:-0.131923960423;HNF1A:-0.154768114113;PAX3,7:-0.16062439002;NR1H4:-0.161666217889;RXR{A,B,G}:-0.162937195456;GFI1B:-0.164914154535;NANOG:-0.176142306309;ZNF384:-0.180443588282;ATF4:-0.183442366818;PDX1:-0.184504081399;HNF4A_NR2F1,2:-0.188925169645;NFIX:-0.205757071844;HLF:-0.213174307787;ESR1:-0.234414414201;T:-0.269498630903;LEF1_TCF7_TCF7L1,2:-0.280982737386;PBX1:-0.283415229054;GTF2A1,2:-0.29010512276;STAT5{A,B}:-0.295302891505;NKX6-1,2:-0.297783036541;MYBL2:-0.300355321382;GTF2I:-0.303694326092;SRF:-0.314680813815;ATF5_CREB3:-0.322819020081;NR6A1:-0.323792085399;FOXP3:-0.339285110326;EN1,2:-0.346923394534;GATA6:-0.349210097888;NFIL3:-0.353165428615;FOXA2:-0.36392220244;IRF1,2:-0.369070131105;MED-1{core}:-0.405490314454;NFKB1_REL_RELA:-0.415801298714;PAX5:-0.419025593223;MTE{core}:-0.425925216637;MAFB:-0.426374214689;POU5F1:-0.427871599313;RUNX1..3:-0.433454821308;SPIB:-0.439919745935;PAX8:-0.448665665038;ETS1,2:-0.461838554542;UFEwm:-0.462259204763;RREB1:-0.463731038632;ZNF423:-0.468024495556;EGR1..3:-0.472171638571;PRRX1,2:-0.515904047489;ZBTB16:-0.534619723129;MEF2{A,B,C,D}:-0.541782892993;ZNF238:-0.544212458171;AHR_ARNT_ARNT2:-0.56378469353;PAX6:-0.570206483833;PATZ1:-0.586599175708;AR:-0.590466337295;REST:-0.602249636569;SPZ1:-0.612360847959;HMGA1,2:-0.620865304183;HBP1_HMGB_SSRP1_UBTF:-0.622109757921;DMAP1_NCOR{1,2}_SMARC:-0.627198796757;ATF6:-0.627525555749;ATF2:-0.630434526596;NR3C1:-0.630929966254;MYFfamily:-0.648230156013;SPI1:-0.651940615099;GLI1..3:-0.6686692622;TGIF1:-0.6750938282;KLF4:-0.680846928454;HOX{A5,B5}:-0.69753263277;FOXD3:-0.697537247971;PRDM1:-0.709198099385;EVI1:-0.713147760301;TBP:-0.740819076686;GZF1:-0.742294873053;ALX1:-0.765792875503;SOX5:-0.766400057916;TAL1_TCF{3,4,12}:-0.780238074758;BPTF:-0.804538139284;POU6F1:-0.840776002343;SMAD1..7,9:-0.880003358185;XBP1:-0.886190340033;IKZF2:-0.890305506816;FOXL1:-0.911859380294;GCM1,2:-0.923973956202;RXRA_VDR{dimer}:-0.980243123628;POU3F1..4:-0.998110684776;TFAP4:-1.00207146485;STAT2,4,6:-1.01759809388;NFE2L1:-1.02215725918;NHLH1,2:-1.06168933796;ESRRA:-1.1062871624;MZF1:-1.11507278567;JUN:-1.12120730534;NANOG{mouse}:-1.18538629015;DBP:-1.21762425597;TLX2:-1.23849089956;HES1:-1.2689979811;ALX4:-1.33238109367;STAT1,3:-1.42650123533;GATA4:-1.43269509264;NFATC1..3:-1.55551716498;HMX1:-1.81991121532
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|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10434-106E2;search_select_hide=table117:FF:10434-106E2
}}
}}

Latest revision as of 14:01, 3 June 2020

Name:oral squamous cell carcinoma cell line:Ca9-22
Species:Human (Homo sapiens)
Library ID:CNhs10752
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissuegum
dev stageNA
sexmale
ageunknown
cell typeunclassifiable
cell lineCa9-22
companyRIKEN Bioresource centre
collaborationYukio Nakamura (RIKEN BRC)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005721
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs10752 CAGE DRX007972 DRR008844
Accession ID Hg19

Library idBAMCTSS
CNhs10752 DRZ000269 DRZ001654
Accession ID Hg38

Library idBAMCTSS
CNhs10752 DRZ011619 DRZ013004
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)


Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.0184
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.166
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
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C92-CD14CD16-CD14-Eosinophils-Basophils-Neutrophils-Macrophage-Whole0
C93-chronic-acute-leukemia-acantholytic-medulloblastoma-testis-papillotubular0
C94-smallcell-adrenal-lung-nonsmall-small-somatostatinoma-teratocarcinoma0
C95-lung-aorta-trachea-penis-Alveolar-throat-endometrioid0
C96-non-acute-tonsil-spleen-Burkitt-lymphoma-appendix0
C97-small-smallcell-gastrointestinal-argyrophil-putamen-duodenum-brain0
C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample


JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs10752

Jaspar motifP-value
MA0002.20.0201
MA0003.10.629
MA0004.10.405
MA0006.10.141
MA0007.10.0924
MA0009.10.407
MA0014.10.12
MA0017.10.565
MA0018.20.286
MA0019.10.744
MA0024.10.0901
MA0025.10.933
MA0027.10.875
MA0028.13.24707e-6
MA0029.10.889
MA0030.10.0253
MA0031.10.264
MA0035.20.934
MA0038.10.00102
MA0039.26.83014e-4
MA0040.10.956
MA0041.10.323
MA0042.10.54
MA0043.10.963
MA0046.10.854
MA0047.20.945
MA0048.10.418
MA0050.10.989
MA0051.10.343
MA0052.10.00267
MA0055.10.0033
MA0057.10.918
MA0058.10.193
MA0059.10.851
MA0060.17.56572e-8
MA0061.10.00106
MA0062.24.63654e-7
MA0065.20.665
MA0066.10.212
MA0067.10.444
MA0068.10.182
MA0069.10.644
MA0070.10.731
MA0071.10.491
MA0072.10.958
MA0073.10.922
MA0074.10.437
MA0076.17.12886e-6
MA0077.10.489
MA0078.10.435
MA0079.20.104
MA0080.22.6006e-5
MA0081.10.0469
MA0083.10.383
MA0084.10.028
MA0087.10.398
MA0088.10.0845
MA0090.10.157
MA0091.11.81535e-4
MA0092.10.119
MA0093.10.266
MA0099.22.93738e-9
MA0100.10.875
MA0101.10.0149
MA0102.20.486
MA0103.15.4569e-6
MA0104.20.142
MA0105.12.28146e-6
MA0106.17.22198e-9
MA0107.18.26378e-4
MA0108.22.43101e-4
MA0111.10.889
MA0112.20.0733
MA0113.10.17
MA0114.10.417
MA0115.10.733
MA0116.10.0049
MA0117.10.347
MA0119.10.189
MA0122.10.949
MA0124.10.52
MA0125.10.206
MA0131.10.0923
MA0135.10.6
MA0136.10.0097
MA0137.20.2
MA0138.20.0375
MA0139.10.133
MA0140.10.301
MA0141.10.0712
MA0142.10.896
MA0143.10.748
MA0144.10.562
MA0145.10.36
MA0146.10.00139
MA0147.10.144
MA0148.10.446
MA0149.10.136
MA0150.10.00649
MA0152.10.531
MA0153.10.662
MA0154.17.77116e-4
MA0155.10.172
MA0156.10.966
MA0157.10.698
MA0159.10.224
MA0160.10.846
MA0162.10.665
MA0163.10.00837
MA0164.10.931
MA0258.10.291
MA0259.10.569



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs10752

Novel motifP-value
10.759
100.617
1000.514
1010.606
1020.164
1030.647
1040.891
1050.71
1060.00338
1070.0866
1080.853
1090.164
110.425
1100.673
1110.893
1120.571
1130.308
1140.323
1150.66
1160.29
1170.0952
1180.923
1190.121
120.902
1200.982
1210.736
1220.565
1230.682
1240.132
1250.578
1260.677
1270.623
1280.00126
1290.78
130.144
1300.734
1310.252
1320.87
1330.0079
1340.106
1350.034
1360.0349
1370.0379
1380.569
1390.2
140.896
1400.798
1410.668
1420.754
1430.07
1440.309
1450.196
1460.591
1470.994
1480.456
1490.722
150.215
1500.893
1510.834
1520.692
1530.269
1540.89
1550.325
1560.19
1570.926
1580.46
1590.461
160.533
1600.217
1610.908
1620.667
1630.975
1640.997
1650.788
1660.375
1670.781
1680.915
1690.313
170.446
180.174
190.128
20.895
200.445
210.571
220.976
230.0948
240.132
250.893
260.841
270.391
280.385
290.783
30.461
300.397
310.113
320.00323
330.767
340.2
350.0382
360.314
370.821
380.817
390.54
40.805
400.701
410.0801
420.83
430.0642
440.418
450.669
460.151
470.987
480.709
490.0796
50.192
500.627
510.651
520.592
530.958
540.896
550.756
560.997
570.673
580.732
590.204
60.916
600.622
610.644
620.214
630.815
640.456
650.117
660.0124
670.422
680.0788
690.523
70.246
700.942
710.442
720.505
730.395
740.00648
750.355
760.989
770.638
780.67
797.14955e-5
80.139
800.0465
810.0539
820.383
830.219
840.673
850.204
860.889
870.00459
880.345
890.487
90.145
900.0732
910.24
920.18
930.656
940.0381
950.27
960.0668
970.714
980.149
990.386



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs10752


FANTOM5 (FF) ontology


Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000076 (squamous epithelial cell)
0000255 (eukaryotic cell)
0002076 (endo-epithelial cell)
0002251 (epithelial cell of alimentary canal)

DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
7 (disease of anatomical entity)
305 (carcinoma)
1749 (squamous cell carcinoma)

UBERON: Anatomy
0000468 (multi-cellular organism)
0003343 (mucosa of oral region)
0000033 (head)
0000974 (neck)
0001007 (digestive system)
0000344 (mucosa)
0004121 (ectoderm-derived structure)
0000064 (organ part)
0004119 (endoderm-derived structure)
0000062 (organ)
0004111 (anatomical conduit)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000481 (multi-tissue structure)
0004923 (organ component layer)
0000161 (orifice)
0001444 (subdivision of head)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0004785 (respiratory system mucosa)
0003729 (mouth mucosa)
0010317 (germ layer / neural crest derived structure)
0001555 (digestive tract)
0001004 (respiratory system)
0000153 (anterior region of body)
0007811 (craniocervical region)
0000165 (mouth)
0000166 (oral opening)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0102024 (squamous cell carcinoma cell line sample)
0101120 (epithelial cell line sample)
0102211 (oral squamous cell carcinoma cell line sample)
0102027 (oral cancer cell line sample)
0102709 (head and neck squamous cell carcinoma cell line sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000223 (endodermal cell)
UBERON:0002532 (epiblast (generic))
UBERON:0006601 (presumptive ectoderm)
UBERON:0006595 (presumptive endoderm)
UBERON:0010316 (germ layer / neural crest)