Coexpression cluster:C0

Full id: C0_CD14_Eosinophils_Neutrophils_Basophils_CD34_immature_Peripheral

Phase1 CAGE Peaks

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Hg19::chr10:100076685..100076699,+	p@chr10:100076685..100076699 +
Hg19::chr10:101381173..101381230,+	p1@BC029589
Hg19::chr10:101418528..101418547,-	p@chr10:101418528..101418547 -
Hg19::chr10:101754166..101754178,-	p@chr10:101754166..101754178 -
Hg19::chr10:102016880..102016906,-	p@chr10:102016880..102016906 -
Hg19::chr10:104155095..104155101,-	p@chr10:104155095..104155101 -
Hg19::chr10:104155206..104155209,+	p18@NFKB2
Hg19::chr10:104155455..104155479,+	p1@NFKB2
Hg19::chr10:104155659..104155676,+	p4@NFKB2
Hg19::chr10:104156550..104156559,+	p@chr10:104156550..104156559 +
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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p.value	FDR	nGenes	nPathway	Name
0.00425143795626119	0.0321247106720483	4	22	Glycosaminoglycan biosynthesis - chondroitin sulfate (KEGG):00532
0.00133776027585096	0.0130292062417945	6	40	Sphingolipid metabolism (KEGG):00600
6.16097435632278e-08	2.00847764016123e-06	27	265	Cytokine-cytokine receptor interaction (KEGG):04060
8.39741026616912e-05	0.00128322925629897	17	189	Chemokine signaling pathway (KEGG):04062
2.2811600735419e-06	4.64786364984163e-05	13	86	Apoptosis (KEGG):04210
2.16698707745994e-06	4.60720296033875e-05	16	128	Osteoclast differentiation (KEGG):04380
2.85362180913581e-10	1.99345866381059e-08	19	102	Toll-like receptor signaling pathway (KEGG):04620
1.43326395780318e-12	3.50433037682878e-10	17	59	NOD-like receptor signaling pathway (KEGG):04621
2.98273796505281e-08	1.04182776065059e-06	14	71	RIG-I-like receptor signaling pathway (KEGG):04622
4.65531906040374e-09	2.0695009277613e-07	14	62	Cytosolic DNA-sensing pathway (KEGG):04623
0.00107643015425161	0.0107423335801845	13	155	Jak-STAT signaling pathway (KEGG):04630
0.00033354698071338	0.00388343984687721	13	137	Natural killer cell mediated cytotoxicity (KEGG):04650
0.00190037406991627	0.0165943378605189	10	108	T cell receptor signaling pathway (KEGG):04660
0.000100819652716995	0.00149396394480637	10	75	B cell receptor signaling pathway (KEGG):04662
0.00537229544723757	0.0380732242565098	7	69	Adipocytokine signaling pathway (KEGG):04920
0.00023607564663386	0.00288602478009893	9	68	Epithelial cell signaling in Helicobacter pylori infection (KEGG):05120
0.00294564280150295	0.0248348160333611	7	62	Shigellosis (KEGG):05131
1.41068620075766e-05	0.000237870880058792	11	73	Leishmaniasis (KEGG):05140
1.22241943948415e-07	3.73601941192344e-06	16	104	Chagas disease (American trypanosomiasis) (KEGG):05142
0.000644660502273218	0.00700531079136897	6	35	African trypanosomiasis (KEGG):05143
0.000157271928950184	0.00219731352161829	8	51	Malaria (KEGG):05144
3.60455893689099e-06	7.05051728055877e-05	16	133	Toxoplasmosis (KEGG):05145
1.60420729655662e-07	4.47983890382499e-06	16	106	Amoebiasis (KEGG):05146
2.20733370460271e-09	1.07938618155073e-07	24	182	Tuberculosis (KEGG):05152
0.000999859125799526	0.0101860648440827	12	135	Hepatitis C (KEGG):05160
1.69402033826415e-07	4.47983890382499e-06	18	134	Measles (KEGG):05162
1.00245240116991e-12	3.50433037682878e-10	28	176	Influenza A (KEGG):05164
0.00307910681656379	0.0255200548016897	20	327	Pathways in cancer (KEGG):05200
0.00581411580761335	0.0406157518560418	7	70	Pancreatic cancer (KEGG):05212
0.00183366713695132	0.0163029678176217	8	73	Chronic myeloid leukemia (KEGG):05220
0.00028880988830685	0.00344458622883048	10	85	Small cell lung cancer (KEGG):05222
8.5954133337647e-07	2.00150339057664e-05	14	92	Rheumatoid arthritis (KEGG):05323
0.00321712275182436	0.0262195504273685	10	116	Androgen Receptor Signaling Pathway (Wikipathways):WP138
2.30975486902947e-08	8.68823177658008e-07	11	40	NOD pathway (Wikipathways):WP1433
0.00403384949676599	0.031310355617755	3	11	Osteopontin Signaling (Wikipathways):WP1434
5.53701938295192e-11	4.51267079710582e-09	23	140	Regulation of toll-like receptor signaling pathway (Wikipathways):WP1449
1.61601545320517e-05	0.000263410518872442	10	61	Selenium Pathway (Wikipathways):WP15
0.000180897593371529	0.00239078170699129	8	52	Vitamin B12 Metabolism (Wikipathways):WP1533
0.000691494075529239	0.00735088267247386	8	63	Folate Metabolism (Wikipathways):WP176
0.000367776116980188	0.00418238421403051	4	12	IL-1 Signaling Pathway (Wikipathways):WP195
1.61580233506846e-06	3.59148791749308e-05	20	188	TNF-alpha/NF-kB Signaling Pathway (Wikipathways):WP231
1.14986675996699e-05	0.000200816016294235	12	85	Apoptosis (Wikipathways):WP254
1.74063270291768e-07	4.47983890382499e-06	8	22	EBV LMP1 signaling (Wikipathways):WP262
0.00160898819308834	0.0147449332712717	13	162	MAPK signaling pathway (Wikipathways):WP382
0.00385008824336014	0.0303660185645663	13	179	EGFR1 Signaling Pathway (Wikipathways):WP437
0.00060441809326353	0.00671728290013332	9	77	IL-2 Signaling Pathway (Wikipathways):WP49
0.00356449396276462	0.0285743860293754	4	21	Hypertrophy Model (Wikipathways):WP516
0.00625774384747697	0.0425005102974478	6	54	Id Signaling Pathway (Wikipathways):WP53
4.15950186831576e-06	7.53332005039409e-05	7	23	Cytokines and Inflammatory Response (Wikipathways):WP530
6.02879889275282e-05	0.000950994405985848	12	100	Senescence and Autophagy (Wikipathways):WP615
0.00427015581530295	0.0321247106720483	6	50	Type II interferon signaling (IFNG) (Wikipathways):WP619
0.00283480940584391	0.0243196806922399	11	133	T Cell Receptor Signaling Pathway (Wikipathways):WP69
0.00456467840515538	0.0338201172745603	7	67	SIDS Susceptibility Pathways (Wikipathways):WP706
3.64203216596464e-11	3.56190745831342e-09	20	102	Toll-like receptor signaling pathway (Wikipathways):WP75
2.68672083884993e-11	3.28451622549404e-09	47	511	Signaling in Immune system (Reactome):REACT_6900
0.000175974305187767	0.00239031764546718	18	220	Signalling by NGF (Reactome):REACT_11061
0.00142050460013546	0.0133582067205046	27	466	Hemostasis (Reactome):REACT_604
0.00605054306298933	0.0416720501098843	11	147	Apoptosis (Reactome):REACT_578
0.00135887427061661	0.0130292062417945	13	159	EGFR1 up reg. targets (Netpath):NetPath_4
0.000923359216192706	0.00960686503655816	41	792	TGF beta receptor up reg. targets (Netpath):NetPath_7
7.02643407662666e-09	2.86327188622536e-07	53	728	TNF alpha/NF-kB up reg. targets (Netpath):NetPath_9
0.000156987196872601	0.00219731352161829	15	162	TNF alpha/NF-kB down reg. targets (Netpath):NetPath_9
0.00499127425830448	0.0358931340045719	24	437	AR up reg. targets (Netpath):NetPath_2
0.000200594694564588	0.00251514886261753	19	242	B Cell Receptor up reg. targets (Netpath):NetPath_12
0.00495612963722777	0.0358931340045719	7	68	T Cell Receptor down reg. targets (Netpath):NetPath_11
3.97380638898368e-10	2.42898915526627e-08	23	154	IL-1 up reg. targets (Netpath):NetPath_13
1.60580701659313e-09	8.72488479015602e-08	38	408	IL-2 up reg. targets (Netpath):NetPath_14
0.000200431451342285	0.00251514886261753	7	40	IL-3 up reg. targets (Netpath):NetPath_15
4.10090011459927e-06	7.53332005039409e-05	21	217	IL-4 up reg. targets (Netpath):NetPath_16
6.52648255274034e-07	1.59572498414501e-05	14	90	IL-4 down reg. targets (Netpath):NetPath_16
1.14947300330197e-11	1.87364099538221e-09	23	130	IL-5 up reg. targets (Netpath):NetPath_17
0.00162827483977233	0.0147449332712717	7	56	IL-7 up reg. targets (Netpath):NetPath_19

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0006915	apoptosis	2.82155838612429e-38
GO:0012501	programmed cell death	4.30019346162364e-38
GO:0042981	regulation of apoptosis	3.82648948649562e-37
GO:0008219	cell death	3.82648948649562e-37
GO:0016265	death	3.82648948649562e-37
GO:0043067	regulation of programmed cell death	9.79237786394369e-37
GO:0006952	defense response	4.52286243115286e-36
GO:0048468	cell development	4.38532462994828e-29
GO:0009611	response to wounding	1.69742030521152e-28
GO:0005515	protein binding	2.33064392541438e-28
GO:0048519	negative regulation of biological process	1.27326296722392e-26
GO:0048523	negative regulation of cellular process	5.83954096385085e-26
GO:0009605	response to external stimulus	2.52299407138837e-25
GO:0048869	cellular developmental process	3.47153444569286e-23
GO:0030154	cell differentiation	3.47153444569286e-23
GO:0008134	transcription factor binding	3.21149186137499e-20
GO:0042221	response to chemical stimulus	3.50768601539619e-20
GO:0005737	cytoplasm	3.50768601539619e-20
GO:0006950	response to stress	9.49390885459372e-20
GO:0032502	developmental process	2.26230536930081e-19
GO:0007243	protein kinase cascade	4.26811717177096e-19
GO:0006366	transcription from RNA polymerase II promoter	4.58177148627513e-19
GO:0065007	biological regulation	3.21802439025239e-18
GO:0002376	immune system process	2.74639736238171e-17
GO:0044424	intracellular part	3.02318417547877e-17
GO:0006955	immune response	8.88609069086369e-17
GO:0043231	intracellular membrane-bound organelle	1.2315871002741e-16
GO:0043227	membrane-bound organelle	1.24580966345322e-16
GO:0048522	positive regulation of cellular process	1.32666633999274e-16
GO:0044464	cell part	1.43375613209818e-15
GO:0050789	regulation of biological process	1.67848645022775e-15
GO:0048518	positive regulation of biological process	1.82101148007379e-15
GO:0007154	cell communication	5.97725977850706e-15
GO:0005622	intracellular	1.53766800305527e-14
GO:0007165	signal transduction	1.91357639330645e-14
GO:0009607	response to biotic stimulus	7.01156789387207e-14
GO:0006954	inflammatory response	8.14521204875488e-14
GO:0050794	regulation of cellular process	8.16632892335978e-14
GO:0007242	intracellular signaling cascade	3.7694992246852e-13
GO:0043066	negative regulation of apoptosis	1.03727483182521e-12
GO:0043069	negative regulation of programmed cell death	1.35776338302123e-12
GO:0007249	I-kappaB kinase/NF-kappaB cascade	5.12768078779641e-12
GO:0008283	cell proliferation	1.19569595931674e-11
GO:0006916	anti-apoptosis	1.93129758626022e-10
GO:0009615	response to virus	3.71181433272232e-10
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	1.53366105792894e-09
GO:0006357	regulation of transcription from RNA polymerase II promoter	3.12630028398356e-09
GO:0007626	locomotory behavior	4.67660036177271e-09
GO:0051707	response to other organism	5.09483202541185e-09
GO:0043229	intracellular organelle	7.03153349515065e-09
GO:0043226	organelle	7.25112627317426e-09
GO:0009892	negative regulation of metabolic process	8.76143317608488e-09
GO:0006935	chemotaxis	8.82638696589805e-09
GO:0042330	taxis	8.82638696589805e-09
GO:0007610	behavior	8.95702928372013e-09
GO:0031324	negative regulation of cellular metabolic process	1.62005710673607e-08
GO:0051704	multi-organism process	1.62531946449851e-08
GO:0031090	organelle membrane	2.3478276795309e-08
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	5.117600999026e-08
GO:0003712	transcription cofactor activity	7.98687831331886e-08
GO:0042127	regulation of cell proliferation	9.79816151494911e-08
GO:0005125	cytokine activity	1.23182864467458e-07
GO:0043065	positive regulation of apoptosis	1.54763727674924e-07
GO:0009967	positive regulation of signal transduction	1.58147530129321e-07
GO:0043068	positive regulation of programmed cell death	1.70468463835292e-07
GO:0044444	cytoplasmic part	2.25514851075708e-07
GO:0001775	cell activation	2.45063552660924e-07
GO:0016564	transcription repressor activity	3.44237195030314e-07
GO:0065008	regulation of biological quality	4.19556217735769e-07
GO:0005615	extracellular space	4.3012024609811e-07
GO:0046983	protein dimerization activity	7.99831860400417e-07
GO:0003714	transcription corepressor activity	1.11616923329408e-06
GO:0005887	integral to plasma membrane	1.14759226115259e-06
GO:0012505	endomembrane system	1.36137582980121e-06
GO:0006917	induction of apoptosis	1.74108984041341e-06
GO:0031226	intrinsic to plasma membrane	1.77442800656045e-06
GO:0012502	induction of programmed cell death	1.81058331661258e-06
GO:0065009	regulation of a molecular function	2.06098528185151e-06
GO:0019222	regulation of metabolic process	2.30076716342493e-06
GO:0009653	anatomical structure morphogenesis	2.45359089775718e-06
GO:0009966	regulation of signal transduction	2.99490168014221e-06
GO:0016044	membrane organization and biogenesis	3.40381947412256e-06
GO:0051246	regulation of protein metabolic process	3.40381947412256e-06
GO:0005102	receptor binding	7.21674198536009e-06
GO:0045321	leukocyte activation	7.21674198536009e-06
GO:0015031	protein transport	7.35482717135834e-06
GO:0008104	protein localization	1.01545018183615e-05
GO:0048856	anatomical structure development	1.13574820658782e-05
GO:0042107	cytokine metabolic process	1.13574820658782e-05
GO:0045184	establishment of protein localization	1.13574820658782e-05
GO:0033036	macromolecule localization	1.22925032159805e-05
GO:0016043	cellular component organization and biogenesis	1.22925032159805e-05
GO:0005634	nucleus	1.26908879102043e-05
GO:0001816	cytokine production	1.36612090277039e-05
GO:0045087	innate immune response	1.47765655059546e-05
GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	1.60827141009002e-05
GO:0046651	lymphocyte proliferation	1.63549245593885e-05
GO:0032943	mononuclear cell proliferation	1.63549245593885e-05
GO:0010324	membrane invagination	1.83513798410923e-05
GO:0006897	endocytosis	1.83513798410923e-05
GO:0016481	negative regulation of transcription	1.9390028258885e-05
GO:0000267	cell fraction	2.22554090171985e-05
GO:0005773	vacuole	2.52669001513912e-05
GO:0019955	cytokine binding	2.88662635299605e-05
GO:0051789	response to protein stimulus	3.51780051572191e-05
GO:0006986	response to unfolded protein	3.51780051572191e-05
GO:0004857	enzyme inhibitor activity	5.89627428229136e-05
GO:0016020	membrane	7.33392447406938e-05
GO:0031323	regulation of cellular metabolic process	7.88931376616658e-05
GO:0008285	negative regulation of cell proliferation	8.01430036312347e-05
GO:0042089	cytokine biosynthetic process	8.96930857765273e-05
GO:0050790	regulation of catalytic activity	9.15003574705003e-05
GO:0005764	lysosome	0.000113705978160445
GO:0000323	lytic vacuole	0.000118966186359792
GO:0005625	soluble fraction	0.000119799311106425
GO:0009891	positive regulation of biosynthetic process	0.000119799311106425
GO:0045595	regulation of cell differentiation	0.000120208830006632
GO:0032501	multicellular organismal process	0.000151952924171659
GO:0006928	cell motility	0.000151952924171659
GO:0051674	localization of cell	0.000151952924171659
GO:0044428	nuclear part	0.000151952924171659
GO:0031967	organelle envelope	0.000165225973085146
GO:0045727	positive regulation of translation	0.000165225973085146
GO:0031975	envelope	0.000176234544149473
GO:0009893	positive regulation of metabolic process	0.000224829558528669
GO:0046649	lymphocyte activation	0.000224829558528669
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	0.000224829558528669
GO:0009889	regulation of biosynthetic process	0.000229244936782068
GO:0042060	wound healing	0.000290634025120562
GO:0010468	regulation of gene expression	0.000311033851677216
GO:0044422	organelle part	0.000325594337086304
GO:0019965	interleukin binding	0.000325755725926754
GO:0031328	positive regulation of cellular biosynthetic process	0.000352198537174818
GO:0016021	integral to membrane	0.000355687059591395
GO:0031325	positive regulation of cellular metabolic process	0.000387140826751875
GO:0019210	kinase inhibitor activity	0.000422103933132849
GO:0005794	Golgi apparatus	0.000439533255244161
GO:0031224	intrinsic to membrane	0.000449791661990567
GO:0050793	regulation of developmental process	0.000511158220563289
GO:0045892	negative regulation of transcription, DNA-dependent	0.000511284689175166
GO:0044446	intracellular organelle part	0.000511284689175166
GO:0048534	hemopoietic or lymphoid organ development	0.000556950870843402
GO:0044425	membrane part	0.0005941559116859
GO:0030155	regulation of cell adhesion	0.000610734372986969
GO:0002521	leukocyte differentiation	0.00061817163159462
GO:0031988	membrane-bound vesicle	0.000646237996023023
GO:0006665	sphingolipid metabolic process	0.000723657169215303
GO:0045103	intermediate filament-based process	0.000723657169215303
GO:0004896	hematopoietin/interferon-class (D200-domain) cytokine receptor activity	0.000789023688173291
GO:0042104	positive regulation of activated T cell proliferation	0.00083105644625646
GO:0002520	immune system development	0.000832329179828814
GO:0006417	regulation of translation	0.000912877718189989
GO:0005070	SH3/SH2 adaptor activity	0.00091713472719007
GO:0005149	interleukin-1 receptor binding	0.00091713472719007
GO:0006807	nitrogen compound metabolic process	0.000927759553128225
GO:0005783	endoplasmic reticulum	0.000927759553128225
GO:0031410	cytoplasmic vesicle	0.000935578027622508
GO:0003700	transcription factor activity	0.00096138988813216
GO:0007275	multicellular organismal development	0.000988507170026859
GO:0043085	positive regulation of catalytic activity	0.00102372149616865
GO:0042110	T cell activation	0.00102643646773933
GO:0050792	regulation of viral reproduction	0.00112763132897539
GO:0031982	vesicle	0.00122152865484213
GO:0046006	regulation of activated T cell proliferation	0.00130480945138339
GO:0050798	activated T cell proliferation	0.00130480945138339
GO:0030097	hemopoiesis	0.00130480945138339
GO:0051345	positive regulation of hydrolase activity	0.00130480945138339
GO:0008009	chemokine activity	0.00130480945138339
GO:0005635	nuclear envelope	0.00132014703450103
GO:0030101	natural killer cell activation	0.001358486772226
GO:0051059	NF-kappaB binding	0.001358486772226
GO:0042379	chemokine receptor binding	0.00137735530470173
GO:0051093	negative regulation of developmental process	0.00137735530470173
GO:0051179	localization	0.00138157981065815
GO:0004907	interleukin receptor activity	0.00138157981065815
GO:0045637	regulation of myeloid cell differentiation	0.00138157981065815
GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.00149424988886489
GO:0031326	regulation of cellular biosynthetic process	0.00156687658257701
GO:0046519	sphingoid metabolic process	0.00156687658257701
GO:0016023	cytoplasmic membrane-bound vesicle	0.00158504287341581
GO:0005829	cytosol	0.00161694006127387
GO:0006351	transcription, DNA-dependent	0.00179382860798935
GO:0006886	intracellular protein transport	0.00184531535604419
GO:0032774	RNA biosynthetic process	0.00187104828443725
GO:0006350	transcription	0.00195374029568989
GO:0048731	system development	0.0021130107996425
GO:0005886	plasma membrane	0.00219695700479453
GO:0015837	amine transport	0.00219695700479453
GO:0060090	molecular adaptor activity	0.00232874407908844
GO:0042035	regulation of cytokine biosynthetic process	0.00232874407908844
GO:0051247	positive regulation of protein metabolic process	0.00232874407908844
GO:0033188	sphingomyelin synthase activity	0.00237619418841371
GO:0001660	fever	0.00237619418841371
GO:0019969	interleukin-10 binding	0.00237619418841371
GO:0047493	ceramide cholinephosphotransferase activity	0.00237619418841371
GO:0004920	interleukin-10 receptor activity	0.00237619418841371
GO:0005057	receptor signaling protein activity	0.00240047202560076
GO:0042098	T cell proliferation	0.00240047202560076
GO:0045449	regulation of transcription	0.00242989245792357
GO:0044421	extracellular region part	0.00259226750528049
GO:0000060	protein import into nucleus, translocation	0.00264405196243603
GO:0004860	protein kinase inhibitor activity	0.00265866190433511
GO:0044238	primary metabolic process	0.00266152219527465
GO:0005789	endoplasmic reticulum membrane	0.00275978420661588
GO:0042108	positive regulation of cytokine biosynthetic process	0.00294987998788739
GO:0009308	amine metabolic process	0.00300814852704178
GO:0045596	negative regulation of cell differentiation	0.00326183470691838
GO:0007267	cell-cell signaling	0.00326183470691838
GO:0050755	chemokine metabolic process	0.00326183470691838
GO:0042033	chemokine biosynthetic process	0.00326183470691838
GO:0002263	cell activation during immune response	0.00326183470691838
GO:0002294	CD4-positive, alpha-beta T cell differentiation during immune response	0.00326183470691838
GO:0002285	lymphocyte activation during immune response	0.00326183470691838
GO:0002292	T cell differentiation during immune response	0.00326183470691838
GO:0032602	chemokine production	0.00326183470691838
GO:0042092	T-helper 2 type immune response	0.00326183470691838
GO:0042093	T-helper cell differentiation	0.00326183470691838
GO:0002366	leukocyte activation during immune response	0.00326183470691838
GO:0002286	T cell activation during immune response	0.00326183470691838
GO:0002293	alpha-beta T cell differentiation during immune response	0.00326183470691838
GO:0045787	positive regulation of progression through cell cycle	0.00341745913540001
GO:0042175	nuclear envelope-endoplasmic reticulum network	0.00352602718730107
GO:0006355	regulation of transcription, DNA-dependent	0.00393174871000502
GO:0050878	regulation of body fluid levels	0.00398708508095322
GO:0007049	cell cycle	0.00415384449831152
GO:0006606	protein import into nucleus	0.00415384449831152
GO:0005319	lipid transporter activity	0.00415384449831152
GO:0016192	vesicle-mediated transport	0.00426171375586573
GO:0043367	CD4-positive, alpha beta T cell differentiation	0.00426444448837713
GO:0016070	RNA metabolic process	0.0044632180260162
GO:0048513	organ development	0.00447729929163255
GO:0046942	carboxylic acid transport	0.00458736949342454
GO:0051170	nuclear import	0.00458736949342454
GO:0001525	angiogenesis	0.00471475930186107
GO:0000074	regulation of progression through cell cycle	0.00481638801895165
GO:0015849	organic acid transport	0.00481638801895165
GO:0006968	cellular defense response	0.00507505929187313
GO:0007596	blood coagulation	0.00507505929187313
GO:0042592	homeostatic process	0.00514357214563959
GO:0042345	regulation of NF-kappaB import into nucleus	0.00530327482144743
GO:0042226	interleukin-6 biosynthetic process	0.00530327482144743
GO:0042088	T-helper 1 type immune response	0.00530327482144743
GO:0042348	NF-kappaB import into nucleus	0.00530327482144743
GO:0051239	regulation of multicellular organismal process	0.00538713959256394
GO:0051726	regulation of cell cycle	0.00547101395066318
GO:0050817	coagulation	0.00553211840410787
GO:0019987	negative regulation of anti-apoptosis	0.00553736821903228
GO:0006686	sphingomyelin biosynthetic process	0.00553736821903228
GO:0008296	3'-5'-exodeoxyribonuclease activity	0.00553736821903228
GO:0015917	aminophospholipid transport	0.00553736821903228
GO:0051223	regulation of protein transport	0.0055494623958941
GO:0003702	RNA polymerase II transcription factor activity	0.00555231662741092
GO:0044237	cellular metabolic process	0.00555231662741092
GO:0001664	G-protein-coupled receptor binding	0.00601953964958593
GO:0007219	Notch signaling pathway	0.0060301053817421
GO:0019058	viral infectious cycle	0.0060301053817421
GO:0008361	regulation of cell size	0.00614008991780483
GO:0006664	glycolipid metabolic process	0.00615570142066165
GO:0019079	viral genome replication	0.00615570142066165
GO:0002250	adaptive immune response	0.00615570142066165
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	0.00615570142066165
GO:0007599	hemostasis	0.00615570142066165
GO:0046982	protein heterodimerization activity	0.00615570142066165
GO:0045069	regulation of viral genome replication	0.00622328046715973
GO:0001836	release of cytochrome c from mitochondria	0.00622328046715973
GO:0046330	positive regulation of JNK cascade	0.00622328046715973
GO:0022402	cell cycle process	0.00622328046715973
GO:0005770	late endosome	0.00629077700141909
GO:0051251	positive regulation of lymphocyte activation	0.00629077700141909
GO:0030099	myeloid cell differentiation	0.00639082951216603
GO:0050671	positive regulation of lymphocyte proliferation	0.00670598489058402
GO:0032946	positive regulation of mononuclear cell proliferation	0.00670598489058402
GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.00697926530695205
GO:0016604	nuclear body	0.00698659345429287
GO:0007264	small GTPase mediated signal transduction	0.00748620458810663
GO:0050900	leukocyte migration	0.00748620458810663
GO:0044451	nucleoplasm part	0.00748620458810663
GO:0045104	intermediate filament cytoskeleton organization and biogenesis	0.00748620458810663
GO:0001776	leukocyte homeostasis	0.00748620458810663
GO:0002252	immune effector process	0.0076207198285098
GO:0006953	acute-phase response	0.00830390236773259
GO:0006672	ceramide metabolic process	0.00830390236773259
GO:0030149	sphingolipid catabolic process	0.00903509977217233
GO:0032635	interleukin-6 production	0.00903509977217233
GO:0048872	homeostasis of number of cells	0.00903509977217233
GO:0002761	regulation of myeloid leukocyte differentiation	0.00903509977217233
GO:0048514	blood vessel morphogenesis	0.00906041477253376
GO:0045628	regulation of T-helper 2 cell differentiation	0.00936255842864794
GO:0002467	germinal center formation	0.00936255842864794
GO:0031649	heat generation	0.00936255842864794
GO:0051058	negative regulation of small GTPase mediated signal transduction	0.00936255842864794
GO:0048525	negative regulation of viral reproduction	0.00936255842864794
GO:0004942	anaphylatoxin receptor activity	0.00936255842864794
GO:0022415	viral reproductive process	0.00958609154743844
GO:0003713	transcription coactivator activity	0.010420405074686
GO:0045786	negative regulation of progression through cell cycle	0.010420405074686
GO:0046632	alpha-beta T cell differentiation	0.01059852377972
GO:0051336	regulation of hydrolase activity	0.0107260233697735
GO:0050863	regulation of T cell activation	0.0110182562004765
GO:0048646	anatomical structure formation	0.0111989336329861
GO:0003677	DNA binding	0.0116203788181476
GO:0043281	regulation of caspase activity	0.011766862976519
GO:0031901	early endosome membrane	0.0124856005982844
GO:0005768	endosome	0.0125751032849673
GO:0006643	membrane lipid metabolic process	0.0125751032849673
GO:0017038	protein import	0.0127025902386353
GO:0019207	kinase regulator activity	0.0127025902386353
GO:0019722	calcium-mediated signaling	0.013203461712667
GO:0005654	nucleoplasm	0.013203461712667
GO:0030674	protein binding, bridging	0.0133070848537221
GO:0044432	endoplasmic reticulum part	0.0134913819234328
GO:0030133	transport vesicle	0.0140249637397094
GO:0044459	plasma membrane part	0.0140249637397094
GO:0042100	B cell proliferation	0.0140249637397094
GO:0045638	negative regulation of myeloid cell differentiation	0.0140249637397094
GO:0045931	positive regulation of progression through mitotic cell cycle	0.0140249637397094
GO:0042347	negative regulation of NF-kappaB import into nucleus	0.0140249637397094
GO:0045064	T-helper 2 cell differentiation	0.0140249637397094
GO:0046479	glycosphingolipid catabolic process	0.0140249637397094
GO:0004439	phosphoinositide 5-phosphatase activity	0.0140249637397094
GO:0045410	positive regulation of interleukin-6 biosynthetic process	0.0140249637397094
GO:0046521	sphingoid catabolic process	0.0140249637397094
GO:0001671	ATPase activator activity	0.0140249637397094
GO:0000902	cell morphogenesis	0.0143589885072513
GO:0032989	cellular structure morphogenesis	0.0143589885072513
GO:0045941	positive regulation of transcription	0.0143589885072513
GO:0030098	lymphocyte differentiation	0.0145016297326039
GO:0047485	protein N-terminus binding	0.0150839065927119
GO:0005164	tumor necrosis factor receptor binding	0.0150839065927119
GO:0016049	cell growth	0.0153205786855536
GO:0044255	cellular lipid metabolic process	0.0154215277577821
GO:0001568	blood vessel development	0.0156672545390817
GO:0008637	apoptotic mitochondrial changes	0.0157648660487551
GO:0046631	alpha-beta T cell activation	0.0157648660487551
GO:0046328	regulation of JNK cascade	0.0157648660487551
GO:0001944	vasculature development	0.0166915177205231
GO:0001817	regulation of cytokine production	0.0175841636467835
GO:0030217	T cell differentiation	0.0175841636467835
GO:0050870	positive regulation of T cell activation	0.0175841636467835
GO:0032813	tumor necrosis factor receptor superfamily binding	0.0175841636467835
GO:0043283	biopolymer metabolic process	0.018843989321751
GO:0050670	regulation of lymphocyte proliferation	0.0190568595240103
GO:0032944	regulation of mononuclear cell proliferation	0.0190568595240103
GO:0050806	positive regulation of synaptic transmission	0.0191816686564672
GO:0043331	response to dsRNA	0.0191816686564672
GO:0005381	iron ion transmembrane transporter activity	0.0191816686564672
GO:0043029	T cell homeostasis	0.0191816686564672
GO:0010224	response to UV-B	0.0191816686564672
GO:0043027	caspase inhibitor activity	0.0191816686564672
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB cascade	0.0191816686564672
GO:0001848	complement binding	0.0191816686564672
GO:0006869	lipid transport	0.0196203427516284
GO:0004871	signal transducer activity	0.0196203427516284
GO:0060089	molecular transducer activity	0.0196203427516284
GO:0007050	cell cycle arrest	0.0196714590177986
GO:0006865	amino acid transport	0.0196714590177986
GO:0006023	aminoglycan biosynthetic process	0.0196714590177986
GO:0030148	sphingolipid biosynthetic process	0.0196714590177986
GO:0042990	regulation of transcription factor import into nucleus	0.0196714590177986
GO:0042991	transcription factor import into nucleus	0.0196714590177986
GO:0043028	caspase regulator activity	0.0196714590177986
GO:0019221	cytokine and chemokine mediated signaling pathway	0.0196934673497123
GO:0031981	nuclear lumen	0.0220531533072953
GO:0009968	negative regulation of signal transduction	0.0221161848092111
GO:0046209	nitric oxide metabolic process	0.0221161848092111
GO:0033157	regulation of intracellular protein transport	0.0221161848092111
GO:0042306	regulation of protein import into nucleus	0.0221161848092111
GO:0006809	nitric oxide biosynthetic process	0.0221161848092111
GO:0042802	identical protein binding	0.0239023293935593
GO:0022414	reproductive process	0.0245131519419456
GO:0030595	leukocyte chemotaxis	0.0245131519419456
GO:0051092	activation of NF-kappaB transcription factor	0.0245131519419456
GO:0001819	positive regulation of cytokine production	0.0245131519419456
GO:0019377	glycolipid catabolic process	0.0245131519419456
GO:0045604	regulation of epidermal cell differentiation	0.0245131519419456
GO:0051971	positive regulation of transmission of nerve impulse	0.0245131519419456
GO:0045622	regulation of T-helper cell differentiation	0.0245131519419456
GO:0001659	thermoregulation	0.0245131519419456
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	0.0245131519419456
GO:0033176	proton-transporting V-type ATPase complex	0.0245131519419456
GO:0016471	vacuolar proton-transporting V-type ATPase complex	0.0245131519419456
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0253073470548377
GO:0009101	glycoprotein biosynthetic process	0.0256057451325749
GO:0051249	regulation of lymphocyte activation	0.0260758135225752
GO:0045893	positive regulation of transcription, DNA-dependent	0.026087260859116
GO:0051234	establishment of localization	0.0263666055598251
GO:0046466	membrane lipid catabolic process	0.0269400336786535
GO:0001669	acrosome	0.0269400336786535
GO:0051049	regulation of transport	0.0273044318264008
GO:0046907	intracellular transport	0.0279874968188689
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.0292559455175994
GO:0032386	regulation of intracellular transport	0.0299173830068333
GO:0042102	positive regulation of T cell proliferation	0.0299173830068333
GO:0002526	acute inflammatory response	0.0299784500933799
GO:0043280	positive regulation of caspase activity	0.0306933325274749
GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.0306933325274749
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	0.0306933325274749
GO:0019915	sequestering of lipid	0.0306933325274749
GO:0031646	positive regulation of neurological process	0.0306933325274749
GO:0045682	regulation of epidermis development	0.0306933325274749
GO:0004529	exodeoxyribonuclease activity	0.0306933325274749
GO:0050865	regulation of cell activation	0.0309928193412919
GO:0003924	GTPase activity	0.0313942531088067
GO:0008284	positive regulation of cell proliferation	0.0328903069278898
GO:0016477	cell migration	0.0328903069278898
GO:0043170	macromolecule metabolic process	0.0337712062668649
GO:0051090	regulation of transcription factor activity	0.0346756150412983
GO:0006913	nucleocytoplasmic transport	0.0346756150412983
GO:0048770	pigment granule	0.0353182088369929
GO:0016607	nuclear speck	0.0353182088369929
GO:0042470	melanosome	0.0353182088369929
GO:0002274	myeloid leukocyte activation	0.0354761656694557
GO:0051169	nuclear transport	0.0366617103186341
GO:0045670	regulation of osteoclast differentiation	0.0376955757790339
GO:0045073	regulation of chemokine biosynthetic process	0.0376955757790339
GO:0015082	di-, tri-valent inorganic cation transmembrane transporter activity	0.0387960606718683
GO:0051649	establishment of cellular localization	0.0406218330745613
GO:0046822	regulation of nucleocytoplasmic transport	0.0427001747422165
GO:0005275	amine transmembrane transporter activity	0.0427001747422165
GO:0006810	transport	0.0447547309812191
GO:0051338	regulation of transferase activity	0.0450335032710592
GO:0045089	positive regulation of innate immune response	0.0450335032710592
GO:0015988	energy coupled proton transport, against electrochemical gradient	0.0450335032710592
GO:0045428	regulation of nitric oxide biosynthetic process	0.0450335032710592
GO:0048146	positive regulation of fibroblast proliferation	0.0450335032710592
GO:0002260	lymphocyte homeostasis	0.0450335032710592
GO:0045408	regulation of interleukin-6 biosynthetic process	0.0450335032710592
GO:0006368	RNA elongation from RNA polymerase II promoter	0.0450335032710592
GO:0007005	mitochondrion organization and biogenesis	0.0450335032710592
GO:0019838	growth factor binding	0.0450335032710592
GO:0008632	apoptotic program	0.0450335032710592
GO:0009306	protein secretion	0.0451842717202546
GO:0006629	lipid metabolic process	0.0452437599223196
GO:0002573	myeloid leukocyte differentiation	0.0452437599223196
GO:0051091	positive regulation of transcription factor activity	0.0452437599223196
GO:0010467	gene expression	0.0460152262916316
GO:0009628	response to abiotic stimulus	0.0465636780063174
GO:0035091	phosphoinositide binding	0.0483747971942848
GO:0009100	glycoprotein metabolic process	0.0486674180329717
GO:0051051	negative regulation of transport	0.0490225225908803

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

---

Cell Type

Ontology term	p-value	n
classical monocyte	1.14e-136	42
CD14-positive, CD16-negative classical monocyte	1.14e-136	42
defensive cell	1.17e-118	48
phagocyte	1.17e-118	48
monopoietic cell	1.94e-93	59
monocyte	1.94e-93	59
monoblast	1.94e-93	59
promonocyte	1.94e-93	59
macrophage dendritic cell progenitor	3.50e-90	61
myeloid leukocyte	3.20e-89	72
myeloid lineage restricted progenitor cell	6.80e-83	66
granulocyte monocyte progenitor cell	1.45e-81	67
stuff accumulating cell	4.15e-62	87
myeloid cell	3.41e-57	108
common myeloid progenitor	3.41e-57	108
nongranular leukocyte	3.42e-56	115
leukocyte	1.67e-54	136
hematopoietic lineage restricted progenitor cell	8.43e-48	120
hematopoietic stem cell	1.14e-42	168
angioblastic mesenchymal cell	1.14e-42	168
hematopoietic oligopotent progenitor cell	3.37e-40	161
hematopoietic multipotent progenitor cell	3.37e-40	161
hematopoietic cell	4.18e-40	177
mesenchymal cell	5.07e-16	354
connective tissue cell	1.50e-15	361
basophil	6.61e-14	3
motile cell	6.87e-14	386
intermediate monocyte	2.04e-12	9
CD14-positive, CD16-positive monocyte	2.04e-12	9
stem cell	4.10e-12	441
multi fate stem cell	7.43e-12	427
somatic stem cell	1.42e-11	433
single nucleate cell	7.14e-07	3
mononuclear cell	7.14e-07	3

Uber Anatomy

Ontology term	p-value	n
bone marrow	3.75e-71	76
bone element	1.83e-65	82
hematopoietic system	2.57e-60	98
blood island	2.57e-60	98
skeletal element	4.79e-59	90
immune system	6.40e-57	93
hemolymphoid system	4.50e-54	108
skeletal system	1.89e-52	100
musculoskeletal system	1.73e-28	167
lateral plate mesoderm	3.02e-25	203
connective tissue	6.59e-15	371
mesoderm	1.76e-13	315
mesoderm-derived structure	1.76e-13	315
presumptive mesoderm	1.76e-13	315

Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
MA0003.1	0
MA0004.1	1.11544
MA0006.1	0
MA0007.1	4.5062e-11
MA0009.1	1.43528
MA0014.1	0
MA0017.1	0.011188
MA0019.1	1.93756
MA0024.1	5.42916e-14
MA0025.1	22.3857
MA0027.1	0.140052
MA0028.1	0
MA0029.1	0.952728
MA0030.1	0.270778
MA0031.1	0.36435
MA0038.1	4.24892
MA0040.1	4.0786
MA0041.1	4.26459
MA0042.1	1.6404
MA0043.1	24.7312
MA0046.1	0.186479
MA0048.1	0
MA0050.1	73.8079
MA0051.1	33.7499
MA0052.1	13.2761
MA0055.1	0
MA0056.1	0
MA0057.1	0
MA0058.1	1.84858
MA0059.1	0.00357571
MA0060.1	0
MA0061.1	47.5321
MA0063.1	0
MA0066.1	0.365589
MA0067.1	2.02941
MA0068.1	0
MA0069.1	1.69004
MA0070.1	1.99351
MA0071.1	7.59878
MA0072.1	11.6236
MA0073.1	0
MA0074.1	0.0866062
MA0076.1	0
MA0077.1	1.41014
MA0078.1	9.02666
MA0081.1	19.095
MA0083.1	1.3804
MA0084.1	1.39156
MA0087.1	5.49778
MA0088.1	0
MA0089.1	0
MA0090.1	0.724867
MA0091.1	1.84208
MA0092.1	1.87417
MA0093.1	1.88889
MA0095.1	0
MA0098.1	0
MA0100.1	6.1109e-09
MA0101.1	83.1469
MA0103.1	0
MA0105.1	4.88949e-06
MA0106.1	2.31631e-13
MA0107.1	140.396
MA0108.2	3.50426
MA0109.1	0
MA0111.1	0.000343328
MA0113.1	0.620266
MA0114.1	1.67529e-08
MA0115.1	0.529326
MA0116.1	0
MA0117.1	0.0654224
MA0119.1	1.52927e-05
MA0122.1	1.62726
MA0124.1	1.629
MA0125.1	0.568921
MA0130.1	0
MA0131.1	0
MA0132.1	0
MA0133.1	0
MA0135.1	1.13653
MA0136.1	51.4555
MA0139.1	0
MA0140.1	0.951066
MA0141.1	0.29159
MA0142.1	6.56023
MA0143.1	2.91076
MA0144.1	1.19938
MA0145.1	0
MA0146.1	0
MA0147.1	0
MA0148.1	4.41667
MA0149.1	6.12348e-15
MA0062.2	0
MA0035.2	2.52552
MA0039.2	0
MA0138.2	2.41082e-16
MA0002.2	12.2851
MA0137.2	1.75127
MA0104.2	0
MA0047.2	1.99336
MA0112.2	0
MA0065.2	0
MA0150.1	141.619
MA0151.1	0
MA0152.1	9.68363
MA0153.1	0.0738614
MA0154.1	4.33947e-15
MA0155.1	0
MA0156.1	46.7855
MA0157.1	1.41144
MA0158.1	0
MA0159.1	0
MA0160.1	2.42853
MA0161.1	0
MA0162.1	0
MA0163.1	0
MA0164.1	4.23742
MA0080.2	103.004
MA0018.2	1.38677
MA0099.2	456.177
MA0079.2	0
MA0102.2	21.1829
MA0258.1	1.48806e-10
MA0259.1	0
MA0442.1	0

ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

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(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF	#promoters	Enrichment	p-value	q-value
BATF#10538	1898	4.52226428658831	0	0
BCL11A#53335	1369	3.7990593795205	0	0
BCL3#602	592	2.00057564900842	8.48333551822493e-58	7.50839896769401e-55
CEBPB#1051	2939	2.29161722315359	0	0
EBF1#1879	2212	1.92713534819629	4.04719890644526e-213	2.0127876504297e-209
EP300#2033	2968	1.96664961786466	2.09297571088206e-318	2.18588290283634e-314
ESR1#2099	415	1.24904336964728	2.47894288092809e-06	8.74656471423139e-05
FOS#2353	3001	2.64138353536067	0	0
FOSL1#8061	913	3.54675714379816	3.33253677358266e-252	2.32031205397467e-248
FOSL2#2355	1249	2.06845549790644	1.50678078702171e-135	3.83821167355513e-132
FOXA2#3170	494	1.19020337413838	3.99254653238326e-05	0.000741689020447484
GATA1#2623	904	1.19911166604672	6.9068635667662e-09	5.39525747232233e-07
GATA2#2624	1752	2.18420428418141	8.849671371124e-222	5.13472682404899e-218
GTF2F1#2962	949	1.18262136085719	3.40278966888747e-08	2.27664285860947e-06
IRF4#3662	1341	2.87463186079662	7.62665558832024e-278	5.68943059277556e-274
JUN#3725	2809	3.43818225582244	0	0
JUNB#3726	1150	3.44343417380361	3.62749017877847e-308	3.15709538984537e-304
JUND#3727	2981	2.03962566866062	0	0
MAFF#23764	415	2.28610710587178	5.51519914622225e-55	4.53544790261658e-52
MAFK#7975	1003	2.65890984419871	1.37134074622533e-179	4.62004697403315e-176
MAX#4149	2038	1.28634531227199	3.0731580805811e-35	1.51395073951797e-32
MEF2A#4205	1385	2.53931084905185	1.54481642571488e-232	9.49053427560211e-229
MEF2C#4208	681	2.75193508847471	7.7496491030809e-128	1.75949044060145e-124
NFE2#4778	308	2.32602096064773	1.57749076009736e-42	9.69126808787106e-40
NFKB1#4790	2874	1.54286357049135	8.24717640886996e-141	2.15331714241492e-137
NR3C1#2908	1214	1.77807398259259	2.68525048572668e-87	3.59544712152318e-84
PAX5#5079	1837	1.19847323493824	1.3831218913685e-17	2.94199322225325e-15
PBX3#5090	515	1.10397867882943	0.0103680832434365	0.0384979644420402
POLR2A#5430	4880	1.02509747643582	0.00762970330486184	0.0314396758120523
POLR3A#11128	65	2.15627380964133	7.14116702412256e-09	5.54922874131202e-07
POU2F2#5452	1407	1.25328343433862	1.74734070245535e-19	4.22431749129015e-17
PRDM1#639	197	2.54041849634743	1.12758828978964e-32	5.05425722735365e-30
RAD21#5885	1164	1.17903349841643	1.47098532611819e-09	1.30858804492724e-07
RXRA#6256	584	1.14678434992212	0.00032725402108409	0.00333542331492157
SIRT6#51548	169	2.53985036430737	3.08294595074528e-28	1.12580346905555e-25
SMARCA4#6597	169	2.59155215289378	2.99237637823681e-29	1.15748443172842e-26
SMARCB1#6598	641	1.14447723913938	0.000207926519591037	0.00242226857552351
SMARCC1#6599	615	2.62672072596824	2.38686329914534e-106	4.45145743034714e-103
SMARCC2#6601	210	1.9341317254865	1.49932186492197e-19	3.66715869439311e-17
SMC3#9126	820	1.20677344545094	1.30186946512873e-08	9.61569625661808e-07
SPI1#6688	2640	2.11869451848772	0	0
SRF#6722	900	1.21465914466898	7.21083451154662e-10	6.85252361739234e-08
STAT1#6772	866	1.7540746133791	7.84186091937372e-59	7.44541920507701e-56
STAT2#6773	362	2.31101292864047	3.79426640285603e-49	2.75187075588806e-46
STAT3#6774	3470	3.57062932017267	0	0
TAL1#6886	537	1.56895697503525	7.62002606221439e-25	2.4189297930444e-22
TCF12#6938	1282	1.33359913964619	4.64000980853966e-27	1.61532661464691e-24
TFAP2A#7020	722	1.16662956249031	9.15310623816763e-06	0.000244423743903858
TFAP2C#7022	1050	1.11021129221884	0.000163174490568725	0.00202999173561729
TRIM28#10155	694	1.26203896912963	1.96500018244104e-10	2.03796081483575e-08
USF1#7391	1779	1.10702408433463	1.09681313843764e-06	4.55286436269032e-05
USF2#7392	1257	1.59749507121515	6.90836954259062e-63	6.74302062297777e-60

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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FF samples	Score

FF samples	Score
CD14+ monocytes - treated with Group A streptococci, donor1 CNhs13469	1.10
CD14+ monocytes - treated with Group A streptococci, donor3 CNhs13492	1.07
CD14+ monocytes - treated with Candida, donor1 CNhs13473	1.05
CD14+ monocytes - treated with Group A streptococci, donor2 CNhs13532	1.01
CD14+ monocytes - treated with Candida, donor2 CNhs13488	0.97
CD14+ monocytes - treated with Candida, donor3 CNhs13494	0.96
CD14+ monocytes - treated with lipopolysaccharide, donor3 CNhs13545	0.95
CD14+ monocytes - treated with Salmonella, donor1 CNhs13471	0.89
CD14+ monocytes - treated with lipopolysaccharide, donor2 CNhs13533	0.86
CD14+ monocytes - treated with Salmonella, donor3 CNhs13493	0.82

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