FF:10545-107H5: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005321 | ||
| | |accession_numbers=CAGE;DRX007974;DRR008846;DRZ000271;DRZ001656;DRZ011621;DRZ013006 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0003343,UBERON:0000033,UBERON:0000974,UBERON:0001007,UBERON:0000344,UBERON:0004121,UBERON:0000064,UBERON:0004119,UBERON:0000062,UBERON:0004111,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0000481,UBERON:0004923,UBERON:0000161,UBERON:0001444,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0004785,UBERON:0003729,UBERON:0010317,UBERON:0001555,UBERON:0001004,UBERON:0000153,UBERON:0007811,UBERON:0000165,UBERON:0000166 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0002371,CL:0000076,CL:0000255,CL:0002076,CL:0002251 | |||
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:7,DOID:305,DOID:1749 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0102024,FF:0101120,FF:0102211,FF:0102027,FF:0102709,FF:0102025 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr3:189507432..189507459,+!p1@TP63!2.23!167.29!TP63;;chr17:7493405..7493419,-!p1@SOX15!2.14!137.94!SOX15;;chr11:34642612..34642646,+!p1@EHF!2.05!110.97!EHF;;chr1:209979467..209979494,-!p1@IRF6!1.88!84.19!IRF6;;chr1:201979743..201979762,+!p1@ELF3!1.82!64.57!ELF3;;chr6:10415276..10415341,-!p2@TFAP2A!1.80!75.57!TFAP2A;;chr6:10415484..10415508,-!p3@TFAP2A!1.72!51.36!TFAP2A;;chr5:2751762..2751784,-!p1@IRX2!1.69!48.06!IRX2;;chr6:10412600..10412637,-!p1@TFAP2A!1.68!76.31!TFAP2A;;chr15:83953397..83953425,-!p1@BNC1!1.63!48.06!BNC1;;chr6:1312325..1312340,+!p1@FOXQ1!1.61!63.10!FOXQ1;;chr13:73633131..73633149,+!p1@KLF5!1.60!389.60!KLF5;;chr1:209979411..209979433,-!p2@IRF6!1.59!37.60!IRF6;;chr17:7492684..7492778,-!p2@SOX15!1.52!66.77!SOX15;;chr12:54785074..54785122,-!p2@ZNF385A!1.52!48.98!ZNF385A;;chr2:176969179..176969226,+!p2@HOXD11!1.49!30.08!HOXD11;;chr2:176969228..176969260,+!p1@HOXD11!1.48!29.35!HOXD11;;chr12:54785054..54785072,-!p4@ZNF385A!1.46!31.18!ZNF385A;;chr1:201979703..201979721,+!p2@ELF3!1.46!27.70!ELF3;;chr15:101069113..101069169,-!p1@CERS3!1.46!27.51!CERS3;;chr3:111314186..111314204,-!p1@ZBED2!1.46!27.51!ZBED2;;chr5:134369905..134369972,-!p1@PITX1!1.45!41.45!PITX1;;chr8:10588010..10588030,-!p1@SOX7!1.44!26.60!SOX7;;chr8:102504651..102504683,+!p1@GRHL2!1.40!24.40!GRHL2;;chr6:10419768..10419819,-!p6@TFAP2A!1.38!22.75!TFAP2A;;chr3:189507523..189507535,+!p5@TP63!1.38!22.75!TP63;;chr17:48072574..48072597,-!p1@DLX3!1.31!19.63!DLX3;;chr1:6479968..6479986,-!p1@HES2!1.30!19.08!HES2;;chr10:48355030..48355090,+!p1@ZNF488!1.29!24.03!ZNF488;;chr6:10412392..10412409,-!p4@TFAP2A!1.29!20.91!TFAP2A;;chr5:2751785..2751808,-!p2@IRX2!1.25!16.69!IRX2;;chr13:73636516..73636532,+!p3@KLF5!1.23!18.34!KLF5;;chr6:126240380..126240430,+!p2@NCOA7!1.20!38.70!NCOA7;;chr17:26833339..26833378,+!p1@FOXN1!1.20!14.67!FOXN1;;chr1:158979792..158979814,+!p2@IFI16!1.19!137.75!IFI16;;chr19:45908292..45908374,-!p1@PPP1R13L!1.18!122.53!PPP1R13L;;chr5:134369879..134369898,-!p2@PITX1!1.17!13.76!PITX1;;chr12:66218836..66218888,+!p1@HMGA2!1.15!123.08!HMGA2;;chr6:10412576..10412599,-!p5@TFAP2A!1.15!13.02!TFAP2A;;chr13:73636252..73636307,+!p2@KLF5!1.14!14.86!KLF5;;chr3:189507460..189507471,+!p3@TP63!1.14!12.84!TP63;;chr19:45971246..45971265,+!p1@FOSB!1.12!227.08!FOSB;;chr17:17726907..17726958,-!p2@SREBF1!1.11!72.82!SREBF1;;chr6:10413188..10413249,-!p7@TFAP2A!1.04!10.09!TFAP2A;;chr8:102504690..102504704,+!p3@GRHL2!1.02!9.54!GRHL2;;chr11:34642656..34642667,+!p2@EHF!1.00!8.99!EHF;;chr12:54332608..54332636,+!p1@HOXC13!0.99!8.80!HOXC13;;chr9:100615499..100615519,+!p1@FOXE1!0.98!8.62!FOXE1;;chr1:158979872..158979898,+!p3@IFI16!0.97!26.60!IFI16;;chr8:71157595..71157616,-!p13@NCOA2!0.97!8.25!NCOA2;;chr11:65554528..65554546,+!p1@OVOL1!0.96!8.07!OVOL1;;chr20:55204351..55204377,+!p1@TFAP2C!0.95!10.09!TFAP2C;;chr17:7492504..7492520,-!p3@SOX15!0.95!7.89!SOX15;;chr12:66218598..66218645,+!p2@HMGA2!0.94!36.87!HMGA2;;chr19:49139477..49139552,-!p4@DBP!0.94!9.91!DBP;;chr12:54332652..54332671,+!p2@HOXC13!0.93!7.52!HOXC13;;chr17:17723626..17723663,-!p4@SREBF1!0.92!15.22!SREBF1;;chr12:66218255..66218304,+!p3@HMGA2!0.91!19.99!HMGA2;;chr17:80797886..80797906,-!p1@ZNF750!0.91!7.15!ZNF750;;chr6:126240356..126240379,+!p7@NCOA7!0.90!8.62!NCOA7;;chr6:10412477..10412490,-!p10@TFAP2A!0.90!6.97!TFAP2A;;chr14:37131058..37131139,+!p1@PAX9!0.90!6.97!PAX9;;chr14:75745523..75745537,+!p1@FOS!0.89!854.96!FOS;;chr22:19748231..19748317,+!p1@TBX1!0.89!6.79!TBX1;;chrY:21906594..21906622,-!p1@KDM5D!0.88!6.60!KDM5D;;chr17:17723746..17723766,-!p5@SREBF1!0.87!10.82!SREBF1;;chr8:49833948..49833973,-!p2@SNAI2!0.86!42.37!SNAI2;;chr2:46524897..46524911,+!p2@EPAS1!0.86!18.16!EPAS1;;chr14:75746722..75746777,+!p2@FOS!0.86!8.07!FOS;;chr3:189526110..189526125,+!p8@TP63!0.85!6.05!TP63;;chr11:129245526..129245553,+!p1@BARX2!0.85!6.05!BARX2;;chr8:102504979..102505010,+!p2@GRHL2!0.85!6.05!GRHL2;;chr20:50721803..50721857,-!p2@ZFP64!0.84!9.72!ZFP64;;chr6:126240442..126240459,+!p4@NCOA7!0.84!7.70!NCOA7;;chr17:17726892..17726903,-!p6@SREBF1!0.84!6.79!SREBF1;;chr12:54332687..54332701,+!p3@HOXC13!0.84!5.87!HOXC13;;chr6:10419824..10419840,-!p9@TFAP2A!0.83!5.69!TFAP2A;;chr3:181429704..181429722,+!p1@SOX2!0.83!5.69!SOX2;;chr12:125002827..125002855,-!p5@NCOR2!0.82!8.25!NCOR2;;chr6:126240463..126240489,+!p6@NCOA7!0.82!6.42!NCOA7;;chr21:36421535..36421610,-!p2@RUNX1!0.80!20.36!RUNX1;;chrX:129244655..129244697,-!p4@ELF4!0.80!9.91!ELF4;;chr22:24093154..24093183,-!p2@ZNF70!0.80!5.32!ZNF70;;chr12:66218573..66218596,+!p7@HMGA2!0.79!7.89!HMGA2;;chr15:83953373..83953386,-!p2@BNC1!0.79!5.14!BNC1;;chr2:172967621..172967637,-!p1@DLX2!0.78!14.49!DLX2;;chr1:158979851..158979865,+!p5@IFI16!0.78!11.74!IFI16;;chr9:14313893..14313908,-!p7@NFIB!0.77!7.34!NFIB;;chr20:62680984..62680999,-!p1@SOX18!0.77!6.60!SOX18;;chrY:2803415..2803468,+!p1@ZFY!0.77!4.95!ZFY;;chr17:46682321..46682362,-!p1@HOXB6!0.77!4.95!HOXB6;;chr19:33793430..33793447,-!p1@CEBPA!0.76!21.64!CEBPA;;chr2:176969124..176969155,+!p5@HOXD11!0.76!4.77!HOXD11;;chr20:6748325..6748352,+!p1@BMP2!0.75!6.97!BMP2;;chr12:125003087..125003141,-!p4@NCOR2!0.75!6.05!NCOR2;;chr12:53625846..53625861,-!p6@RARG!0.75!4.59!RARG;;chr11:120107344..120107351,+!p1@POU2F3!0.74!5.50!POU2F3;;chrX:107019163..107019179,-!p7@TSC22D3!0.74!5.32!TSC22D3;;chr10:51572408..51572454,+!p3@NCOA4!0.73!28.61!NCOA4;;chrX:131623044..131623089,-!p1@MBNL3!0.73!19.81!MBNL3;;chr12:66218212..66218244,+!p5@HMGA2!0.73!6.60!HMGA2;;chr12:54332675..54332686,+!p4@HOXC13!0.73!4.40!HOXC13;;chr3:32023232..32023273,+!p1@ZNF860!0.72!6.42!ZNF860;;chr5:1887052..1887065,-!p2@IRX4!0.72!4.22!IRX4;;chr14:21566731..21566836,-!p1@ZNF219!0.71!49.71!ZNF219;;chr9:14314131..14314147,-!p2@NFIB!0.70!24.95!NFIB;;chr2:60780607..60780624,-!p2@BCL11A!0.70!13.57!BCL11A;;chr12:53625966..53626012,-!p2@RARG!0.70!11.74!RARG;;chr7:27135591..27135658,-!p1@HOXA1!0.70!8.25!HOXA1;;chr2:176969097..176969109,+!p3@HOXD11!0.70!4.04!HOXD11;;chr1:158969752..158969780,+!p6@IFI16!0.69!7.34!IFI16;;chr11:45202580..45202606,+!p@chr11:45202580..45202606,+!0.69!5.14!PRDM11;;chr2:60778035..60778060,-!p4@BCL11A!0.69!4.77!BCL11A;;chr9:137218281..137218340,+!p1@RXRA!0.68!123.08!RXRA;;chr13:41593425..41593480,-!p1@ELF1!0.68!27.70!ELF1;;chr19:49140609..49140643,-!p1@DBP!0.68!24.58!DBP;;chr2:60780753..60780800,-!p1@BCL11A!0.68!21.09!BCL11A;;chr19:49140572..49140594,-!p2@DBP!0.67!6.24!DBP;;chr7:27153454..27153469,-!p2@HOXA3!0.67!3.67!HOXA3;;chr21:40177845..40177863,+!p1@ETS2!0.66!245.06!ETS2;;chrX:107018969..107019024,-!p6@TSC22D3!0.66!5.14!TSC22D3;;chr1:212782094..212782109,+!p1@ATF3!0.65!112.44!ATF3;;chr8:49833978..49833996,-!p1@SNAI2!0.65!82.91!SNAI2;;chr12:53614115..53614154,-!p1@RARG!0.65!21.46!RARG;;chr15:96869255..96869291,+!p6@NR2F2!0.65!6.79!NR2F2;;chr17:17723702..17723721,-!p7@SREBF1!0.65!4.40!SREBF1;;chr11:2292226..2292270,-!p1@ASCL2!0.65!3.49!ASCL2;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!0.65!3.49!HOXC5;;chr12:54694653..54694672,-!p2@NFE2!0.65!3.49!NFE2;;chr6:10415263..10415274,-!p8@TFAP2A!0.65!3.49!TFAP2A;;chr11:47236584..47236679,+!p1@DDB2!0.64!42.74!DDB2;;chr12:80084737..80084763,-!p3@PAWR!0.64!14.31!PAWR;;chr12:125002861..125002894,-!p7@NCOR2!0.64!5.32!NCOR2;;chr17:41623692..41623715,-!p1@ETV4!0.63!16.14!ETV4;;chr1:200379104..200379128,-!p2@ZNF281!0.63!8.99!ZNF281;;chr11:615570..615721,-!p2@IRF7!0.63!7.15!IRF7;;chr13:73636440..73636451,+!p9@KLF5!0.63!3.30!KLF5;;chr14:38064429..38064486,-!p1@FOXA1!0.63!3.30!FOXA1;;chr5:1887070..1887114,-!p1@IRX4!0.63!3.30!IRX4;;chr17:41622731..41622764,-!p5@ETV4!0.63!3.30!ETV4;;chr12:66218378..66218401,+!p6@HMGA2!0.62!5.32!HMGA2;;chr15:67418047..67418093,+!p4@SMAD3!0.62!4.22!SMAD3;;chr12:57919293..57919311,+!p3@MBD6!0.61!9.54!MBD6;;chr8:99956662..99956684,+!p1@OSR2!0.61!5.14!OSR2;;chr1:209979449..209979460,-!p3@IRF6!0.61!3.12!IRF6;;chr1:24645832..24645853,+!p1@GRHL3!0.61!3.12!GRHL3;;chr11:16629261..16629284,-!p1@SOX6!0.61!3.12!SOX6;;chr4:57522598..57522664,-!p3@HOPX!0.61!3.12!HOPX;;chr5:137801160..137801176,+!p1@EGR1!0.60!362.64!EGR1;;chr5:137804484..137804498,+!p2@EGR1!0.60!14.12!EGR1;;chr12:66218183..66218209,+!p4@HMGA2!0.60!6.42!HMGA2;;chr7:17369649..17369664,+!p4@AHR!0.60!3.85!AHR;;chr5:124082322..124082364,-!p1@ZNF608!0.59!8.44!ZNF608;;chr9:1050331..1050363,+!p1@DMRT2!0.59!2.93!DMRT2;;chr2:122042770..122042785,-!p1@TFCP2L1!0.59!2.93!TFCP2L1;;chr3:193853927..193853944,+!p1@HES1!0.58!113.36!HES1;;chr14:35872453..35872485,-!p2@NFKBIA!0.58!7.89!NFKBIA;;chr16:79634595..79634620,-!p2@MAF!0.58!5.69!MAF;;chr13:41635512..41635539,-!p2@ELF1!0.57!18.53!ELF1;;chr14:61116183..61116208,-!p1@SIX1!0.57!12.29!SIX1;;chr5:3595934..3595957,+!p2@IRX1!0.57!2.75!IRX1;;chr8:81787006..81787031,-!p2@ZNF704!0.57!2.75!ZNF704;;chr3:111314230..111314241,-!p2@ZBED2!0.57!2.75!ZBED2;;chr1:40367668..40367684,-!p2@MYCL1!0.57!2.75!MYCL1;;chr20:46130619..46130664,+!p1@NCOA3!0.56!90.25!NCOA3;;chr1:158985493..158985535,+!p4@IFI16!0.56!4.40!IFI16;;chr12:80083544..80083558,-!p13@PAWR!0.56!3.49!PAWR;;chr5:137804405..137804444,+!p3@EGR1!0.56!3.30!EGR1;;chr14:23755297..23755350,-!p1@HOMEZ!0.55!38.15!HOMEZ;;chr16:79634624..79634642,-!p1@MAF!0.55!12.11!MAF;;chr14:23755247..23755278,-!p2@HOMEZ!0.55!5.87!HOMEZ;;chrX:56258844..56258882,+!p1@KLF8!0.55!3.85!KLF8;;chr2:10091815..10091864,+!p1@GRHL1!0.55!3.67!GRHL1;;chr13:100634130..100634143,+!p3@ZIC2!0.55!2.57!ZIC2;;chr13:73636310..73636330,+!p5@KLF5!0.55!2.57!KLF5;;chr19:45908286..45908291,-!p3@PPP1R13L!0.55!2.57!PPP1R13L;;chr20:18038521..18038571,-!p1@OVOL2!0.55!2.57!OVOL2;;chr5:134369222..134369237,-!p8@PITX1!0.55!2.57!PITX1;;chr6:10412338..10412345,-!p17@TFAP2A!0.55!2.57!TFAP2A;;chr7:27190547..27190591,-!p1@HOXA6!0.55!2.57!HOXA6;;chr19:45579725..45579743,-!p1@ZNF296!0.54!13.57!ZNF296;;chr1:8934931..8934947,-!p4@ENO1!0.54!9.91!ENO1;;chr18:3449720..3449749,+!p2@TGIF1!0.54!6.05!TGIF1;;chr12:125002739..125002756,-!p6@NCOR2!0.54!4.04!NCOR2;;chr17:41622765..41622821,-!p2@ETV4!0.53!4.04!ETV4;;chr12:66218443..66218461,+!p8@HMGA2!0.53!3.30!HMGA2;;chr6:85473156..85473210,-!p2@TBX18!0.53!3.12!TBX1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| |||
|ffid_belonging_in_development=CL:0000223,UBERON:0002532,UBERON:0006601,UBERON:0006595,UBERON:0010316 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
| | |||
|fonse_cell_line=FF:0101120,FF:0102027 | |fonse_cell_line=FF:0101120,FF:0102027 | ||
|fonse_cell_line_closure=FF:0101120,FF:0102027 | |fonse_cell_line_closure=FF:0101120,FF:0102027 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/oral%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aHSC-3.CNhs11717.10545-107H5.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/oral%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aHSC-3.CNhs11717.10545-107H5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/oral%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aHSC-3.CNhs11717.10545-107H5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/oral%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aHSC-3.CNhs11717.10545-107H5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/oral%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aHSC-3.CNhs11717.10545-107H5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10545-107H5 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0102025 | |||
|is_obsolete= | |||
|library_id=CNhs11717 | |||
|library_id_phase_based=2:CNhs11717 | |||
|library_ids=CNhs11717 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10545 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10545 | |||
|name=oral squamous cell carcinoma cell line:HSC-3 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11717,LSID819,release009,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.0300937377583703,0,-0.113271818889404,0.10494877384597,0,0,0,0,0,0,0,0,0,0,0.717575460817199,0,0,-0.153323010348428,0,0,0,0,0,0.0377652475787245,0,0,0.0574551780658942,0,0,0,0,0,0,0,0,0,0,0.774704668845825,0,-0.0773891333763509,0.0731420601497836,0,0,0.0731420601497836,0,0,0,0,0.0436465508105566,0,0,0,0,0,-0.0591632007080992,0.0731420601497836,0.0387307826041769,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0.282654506506014,0,0,0,0,0.0731420601497836,0,0,0,0,0,0,0.0495821540575707,0,0,0,-0.167339654640262,0,0,0,-0.0584468268118252,-0.143335830772477,0.0365710300748918,0,0,0,-0.0248932910879228,0.335936504950144,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.096373593922461,0.282654506506014,0,0,-0.0211661170388737,-0.0387513823818764,0,0,0.0731420601497836,0,0,0 | |||
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| |||
|rna_box=107 | |||
|rna_catalog_number= | |||
|rna_concentration=1.06115 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.13 | |||
|rna_od260/280=2.11 | |||
|rna_position=H5 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=107H5 | |||
|rna_weight_ug=37.14025 | |||
|sample_age=64 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB1975 | |||
|sample_cell_line=HSC-3 | |||
|sample_cell_lot= | |||
|sample_cell_type=unclassifiable | |||
|sample_collaboration=Yukio Nakamura (RIKEN BRC) | |||
|sample_company=RIKEN Bioresource centre | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=oral squamous cell carcinoma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;6.151282605841e-247!GO:0043226;organelle;7.22396655733503e-195!GO:0043229;intracellular organelle;2.70022799682188e-194!GO:0043231;intracellular membrane-bound organelle;4.14014157262558e-184!GO:0043227;membrane-bound organelle;4.93176332187794e-184!GO:0005737;cytoplasm;1.29051328349189e-183!GO:0044422;organelle part;5.57037360584676e-146!GO:0044446;intracellular organelle part;2.10834582988651e-144!GO:0044444;cytoplasmic part;6.35367504931731e-119!GO:0032991;macromolecular complex;8.61406321752114e-106!GO:0030529;ribonucleoprotein complex;7.82209279953029e-91!GO:0044237;cellular metabolic process;1.97679203912319e-87!GO:0044238;primary metabolic process;4.51777773853408e-87!GO:0005634;nucleus;5.2327020079055e-82!GO:0005515;protein binding;4.33594546018682e-81!GO:0043170;macromolecule metabolic process;1.13177952144364e-80!GO:0003723;RNA binding;2.83448312084073e-80!GO:0044428;nuclear part;4.85399700040952e-78!GO:0043233;organelle lumen;3.28360997037184e-72!GO:0031974;membrane-enclosed lumen;3.28360997037184e-72!GO:0005739;mitochondrion;4.86641444045469e-63!GO:0006396;RNA processing;5.58685030807452e-55!GO:0006412;translation;4.10754551460726e-54!GO:0043234;protein complex;2.73162364183349e-53!GO:0005840;ribosome;2.77825766623867e-52!GO:0019538;protein metabolic process;8.06716692621591e-52!GO:0016043;cellular component organization and biogenesis;1.11899495167283e-50!GO:0033036;macromolecule localization;2.32562117802884e-47!GO:0031981;nuclear lumen;7.55955660706122e-47!GO:0015031;protein transport;1.89518692807119e-46!GO:0044267;cellular protein metabolic process;4.81433499969707e-46!GO:0043283;biopolymer metabolic process;5.06710725102058e-46!GO:0044260;cellular macromolecule metabolic process;1.44837829624128e-45!GO:0031090;organelle membrane;1.65923877368414e-45!GO:0003735;structural constituent of ribosome;2.41176964802522e-45!GO:0043228;non-membrane-bound organelle;1.34008772638213e-43!GO:0043232;intracellular non-membrane-bound organelle;1.34008772638213e-43!GO:0008104;protein localization;3.7468839331933e-43!GO:0045184;establishment of protein localization;6.28873704479885e-43!GO:0005829;cytosol;2.8427606586083e-42!GO:0016071;mRNA metabolic process;3.58702165796478e-42!GO:0010467;gene expression;1.37796566405308e-41!GO:0009058;biosynthetic process;1.04071159166342e-40!GO:0044429;mitochondrial part;2.22530869630541e-40!GO:0044249;cellular biosynthetic process;3.81515336735159e-40!GO:0033279;ribosomal subunit;6.52398913664188e-40!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.84538859619638e-39!GO:0008380;RNA splicing;2.07518459107163e-39!GO:0031967;organelle envelope;5.50513367255957e-39!GO:0009059;macromolecule biosynthetic process;1.05365436907745e-38!GO:0031975;envelope;1.24831388431691e-38!GO:0006397;mRNA processing;1.23171470120606e-36!GO:0065003;macromolecular complex assembly;4.14819060792175e-36!GO:0022613;ribonucleoprotein complex biogenesis and assembly;3.02605847244607e-34!GO:0006259;DNA metabolic process;8.06087362691495e-34!GO:0006996;organelle organization and biogenesis;1.6001424773264e-33!GO:0046907;intracellular transport;1.74353221375696e-33!GO:0022607;cellular component assembly;2.25842695031811e-31!GO:0006886;intracellular protein transport;3.42198619250432e-31!GO:0005681;spliceosome;6.01871925307616e-29!GO:0005654;nucleoplasm;9.22778025141129e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.12637769679684e-28!GO:0007049;cell cycle;5.90433409381727e-26!GO:0000166;nucleotide binding;6.45130465403781e-26!GO:0005740;mitochondrial envelope;1.01151428964999e-24!GO:0044445;cytosolic part;5.19964786188376e-24!GO:0019866;organelle inner membrane;8.43940945837077e-24!GO:0016462;pyrophosphatase activity;1.06998228024298e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.25104832229412e-23!GO:0031966;mitochondrial membrane;1.38914483801044e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;1.83916632339252e-23!GO:0044451;nucleoplasm part;1.9618434832556e-23!GO:0003676;nucleic acid binding;2.21504984913623e-23!GO:0017111;nucleoside-triphosphatase activity;3.86197854526586e-23!GO:0051649;establishment of cellular localization;2.09595298184482e-22!GO:0051641;cellular localization;3.97258475687273e-22!GO:0006119;oxidative phosphorylation;5.85229884493364e-22!GO:0005743;mitochondrial inner membrane;2.29772631795472e-21!GO:0015935;small ribosomal subunit;2.8829621699627e-21!GO:0016874;ligase activity;1.37087875567236e-20!GO:0022618;protein-RNA complex assembly;1.79636400711312e-20!GO:0022402;cell cycle process;5.38176214229485e-20!GO:0005730;nucleolus;8.96453727831525e-20!GO:0015934;large ribosomal subunit;9.96095059110809e-20!GO:0044455;mitochondrial membrane part;1.3857817880234e-19!GO:0012505;endomembrane system;3.67698996527428e-19!GO:0031980;mitochondrial lumen;9.27137769556701e-19!GO:0005759;mitochondrial matrix;9.27137769556701e-19!GO:0008134;transcription factor binding;1.0268129158527e-18!GO:0048770;pigment granule;1.38985878336116e-18!GO:0042470;melanosome;1.38985878336116e-18!GO:0000278;mitotic cell cycle;2.57320338016019e-18!GO:0006974;response to DNA damage stimulus;2.57970442022324e-18!GO:0000502;proteasome complex (sensu Eukaryota);3.78390921795541e-18!GO:0043285;biopolymer catabolic process;4.81710889913609e-18!GO:0016070;RNA metabolic process;4.81710889913609e-18!GO:0006512;ubiquitin cycle;8.01300308435091e-18!GO:0006605;protein targeting;9.57027547455469e-18!GO:0032553;ribonucleotide binding;1.13347480698277e-17!GO:0032555;purine ribonucleotide binding;1.13347480698277e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;2.02931030763863e-17!GO:0006457;protein folding;2.54565496830991e-17!GO:0017076;purine nucleotide binding;2.60725751584665e-17!GO:0044265;cellular macromolecule catabolic process;2.93545218573377e-17!GO:0019941;modification-dependent protein catabolic process;3.54164274821036e-17!GO:0043632;modification-dependent macromolecule catabolic process;3.54164274821036e-17!GO:0005694;chromosome;4.86687805359173e-17!GO:0044257;cellular protein catabolic process;4.97189487299162e-17!GO:0006511;ubiquitin-dependent protein catabolic process;8.4161818057357e-17!GO:0005746;mitochondrial respiratory chain;1.92939147305496e-16!GO:0051276;chromosome organization and biogenesis;1.96259556260866e-16!GO:0009057;macromolecule catabolic process;4.76238307467004e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;7.00025309618906e-16!GO:0030163;protein catabolic process;1.09669672833259e-15!GO:0008135;translation factor activity, nucleic acid binding;1.2774856296656e-15!GO:0005761;mitochondrial ribosome;1.65705607431171e-15!GO:0000313;organellar ribosome;1.65705607431171e-15!GO:0006281;DNA repair;2.30929195025667e-15!GO:0012501;programmed cell death;2.39418169311063e-15!GO:0005783;endoplasmic reticulum;3.18452584101984e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.22183681915788e-15!GO:0050136;NADH dehydrogenase (quinone) activity;4.43400495303078e-15!GO:0003954;NADH dehydrogenase activity;4.43400495303078e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.43400495303078e-15!GO:0006915;apoptosis;5.20342968440983e-15!GO:0044427;chromosomal part;6.79357631856503e-15!GO:0042254;ribosome biogenesis and assembly;7.8004774350075e-15!GO:0005524;ATP binding;9.19248998080273e-15!GO:0032559;adenyl ribonucleotide binding;1.05448166040394e-14!GO:0005635;nuclear envelope;1.26214880698421e-14!GO:0006325;establishment and/or maintenance of chromatin architecture;1.74657414497469e-14!GO:0030554;adenyl nucleotide binding;3.28531918208072e-14!GO:0008219;cell death;4.21902592200952e-14!GO:0016265;death;4.21902592200952e-14!GO:0000087;M phase of mitotic cell cycle;5.06425670628496e-14!GO:0004386;helicase activity;5.6446417885574e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;5.87016231248006e-14!GO:0000375;RNA splicing, via transesterification reactions;5.87016231248006e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;5.87016231248006e-14!GO:0006323;DNA packaging;8.05487021708981e-14!GO:0007067;mitosis;8.76232745375934e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);9.77156425316665e-14!GO:0044248;cellular catabolic process;1.12591052580208e-13!GO:0016887;ATPase activity;1.13535598209054e-13!GO:0043412;biopolymer modification;1.25578484552079e-13!GO:0006366;transcription from RNA polymerase II promoter;1.56532019677021e-13!GO:0051186;cofactor metabolic process;1.72179553354904e-13!GO:0009719;response to endogenous stimulus;2.35984566726714e-13!GO:0042623;ATPase activity, coupled;2.49001093173082e-13!GO:0031965;nuclear membrane;2.63903321112106e-13!GO:0051726;regulation of cell cycle;2.82097195560194e-13!GO:0006913;nucleocytoplasmic transport;3.14860851110276e-13!GO:0000074;regulation of progression through cell cycle;3.33283335391782e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;4.68771915362328e-13!GO:0051082;unfolded protein binding;4.84569028809616e-13!GO:0030964;NADH dehydrogenase complex (quinone);5.82222423247032e-13!GO:0045271;respiratory chain complex I;5.82222423247032e-13!GO:0005747;mitochondrial respiratory chain complex I;5.82222423247032e-13!GO:0042775;organelle ATP synthesis coupled electron transport;5.88028536810514e-13!GO:0042773;ATP synthesis coupled electron transport;5.88028536810514e-13!GO:0016604;nuclear body;5.90357334597052e-13!GO:0048193;Golgi vesicle transport;6.18242794154242e-13!GO:0044453;nuclear membrane part;6.29117334861226e-13!GO:0003743;translation initiation factor activity;6.72049434379286e-13!GO:0006413;translational initiation;7.47855530701017e-13!GO:0051169;nuclear transport;8.29070153357818e-13!GO:0022403;cell cycle phase;1.12836682208717e-12!GO:0044432;endoplasmic reticulum part;1.5362260326841e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.6151860702822e-12!GO:0006260;DNA replication;2.38073609755537e-12!GO:0005794;Golgi apparatus;1.10247992385729e-11!GO:0006446;regulation of translational initiation;1.41965736355708e-11!GO:0003712;transcription cofactor activity;1.68519033931754e-11!GO:0006732;coenzyme metabolic process;1.71725642647372e-11!GO:0000785;chromatin;1.94746693687802e-11!GO:0009055;electron carrier activity;2.28088962423074e-11!GO:0006464;protein modification process;2.35717102857687e-11!GO:0008026;ATP-dependent helicase activity;3.22169257136723e-11!GO:0008639;small protein conjugating enzyme activity;6.75038311487621e-11!GO:0051301;cell division;7.09229389002399e-11!GO:0006399;tRNA metabolic process;7.68477460022779e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;7.83805590491264e-11!GO:0016192;vesicle-mediated transport;9.11365965896905e-11!GO:0043687;post-translational protein modification;1.00117967815188e-10!GO:0005643;nuclear pore;1.1307269631494e-10!GO:0000279;M phase;1.36899699589569e-10!GO:0004842;ubiquitin-protein ligase activity;1.61781644093009e-10!GO:0043067;regulation of programmed cell death;1.65207838360472e-10!GO:0048523;negative regulation of cellular process;1.67683287211189e-10!GO:0042981;regulation of apoptosis;1.81930932349248e-10!GO:0006461;protein complex assembly;1.81930932349248e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.99512092387589e-10!GO:0016607;nuclear speck;2.10357838567497e-10!GO:0017038;protein import;2.19606198843731e-10!GO:0019787;small conjugating protein ligase activity;2.46042341103878e-10!GO:0008565;protein transporter activity;3.17994024776553e-10!GO:0005789;endoplasmic reticulum membrane;3.88082470902727e-10!GO:0050657;nucleic acid transport;5.60559868090611e-10!GO:0051236;establishment of RNA localization;5.60559868090611e-10!GO:0050658;RNA transport;5.60559868090611e-10!GO:0006403;RNA localization;6.73666027623556e-10!GO:0006364;rRNA processing;7.83282509427419e-10!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.00988060024543e-09!GO:0016072;rRNA metabolic process;1.37503103159994e-09!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.78773464739419e-09!GO:0065004;protein-DNA complex assembly;2.04498592825855e-09!GO:0006333;chromatin assembly or disassembly;2.06776013098464e-09!GO:0048519;negative regulation of biological process;2.58989639732484e-09!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.58989639732484e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.59539403514555e-09!GO:0065002;intracellular protein transport across a membrane;2.89804132431733e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.88680650037923e-09!GO:0016881;acid-amino acid ligase activity;5.18102738617301e-09!GO:0043566;structure-specific DNA binding;6.42176019356985e-09!GO:0030532;small nuclear ribonucleoprotein complex;6.7859453649055e-09!GO:0050794;regulation of cellular process;8.72204176574224e-09!GO:0009259;ribonucleotide metabolic process;8.97475747926743e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.44542458591614e-08!GO:0004812;aminoacyl-tRNA ligase activity;1.44542458591614e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.44542458591614e-08!GO:0051188;cofactor biosynthetic process;1.44665677567115e-08!GO:0046930;pore complex;1.4477207371948e-08!GO:0006163;purine nucleotide metabolic process;1.4477207371948e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.74061511151854e-08!GO:0016568;chromatin modification;1.83189021044809e-08!GO:0015986;ATP synthesis coupled proton transport;2.37621717788746e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.37621717788746e-08!GO:0032446;protein modification by small protein conjugation;2.77017250182274e-08!GO:0016567;protein ubiquitination;3.20975624671272e-08!GO:0043038;amino acid activation;3.26190029646603e-08!GO:0006418;tRNA aminoacylation for protein translation;3.26190029646603e-08!GO:0043039;tRNA aminoacylation;3.26190029646603e-08!GO:0006164;purine nucleotide biosynthetic process;3.43036974650871e-08!GO:0009056;catabolic process;3.58652529446943e-08!GO:0051246;regulation of protein metabolic process;3.58959638727993e-08!GO:0009060;aerobic respiration;3.95791115245902e-08!GO:0016787;hydrolase activity;4.52065430236618e-08!GO:0051028;mRNA transport;4.52065430236618e-08!GO:0005839;proteasome core complex (sensu Eukaryota);4.61953945841758e-08!GO:0009260;ribonucleotide biosynthetic process;5.73926939458087e-08!GO:0009150;purine ribonucleotide metabolic process;6.5186858608132e-08!GO:0043069;negative regulation of programmed cell death;8.69924393933168e-08!GO:0048475;coated membrane;1.20774126091247e-07!GO:0030117;membrane coat;1.20774126091247e-07!GO:0005768;endosome;1.2404237328927e-07!GO:0009108;coenzyme biosynthetic process;1.29049722816559e-07!GO:0031324;negative regulation of cellular metabolic process;1.49851382238478e-07!GO:0003697;single-stranded DNA binding;1.50787039988714e-07!GO:0009141;nucleoside triphosphate metabolic process;1.52483458160875e-07!GO:0009152;purine ribonucleotide biosynthetic process;1.55208066505678e-07!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.5635170067583e-07!GO:0051170;nuclear import;1.68297802767033e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.90206335229999e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.90206335229999e-07!GO:0004298;threonine endopeptidase activity;1.97551698106874e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.21677815664438e-07!GO:0043066;negative regulation of apoptosis;2.2248734394958e-07!GO:0009199;ribonucleoside triphosphate metabolic process;2.27920132437377e-07!GO:0003924;GTPase activity;2.37913237061324e-07!GO:0006754;ATP biosynthetic process;2.38413907924304e-07!GO:0006753;nucleoside phosphate metabolic process;2.38413907924304e-07!GO:0045333;cellular respiration;2.46551087072164e-07!GO:0015078;hydrogen ion transmembrane transporter activity;2.51417369701004e-07!GO:0019829;cation-transporting ATPase activity;2.85419840726516e-07!GO:0030120;vesicle coat;2.87457960594087e-07!GO:0030662;coated vesicle membrane;2.87457960594087e-07!GO:0006357;regulation of transcription from RNA polymerase II promoter;3.02898213515957e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.63401712213033e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.63401712213033e-07!GO:0043623;cellular protein complex assembly;4.23860281170983e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;4.24197974836425e-07!GO:0009144;purine nucleoside triphosphate metabolic process;4.24197974836425e-07!GO:0046034;ATP metabolic process;4.49608255903094e-07!GO:0005793;ER-Golgi intermediate compartment;4.87842303623563e-07!GO:0006606;protein import into nucleus;4.87842303623563e-07!GO:0048522;positive regulation of cellular process;4.89754330327921e-07!GO:0016779;nucleotidyltransferase activity;5.38775411475737e-07!GO:0007005;mitochondrion organization and biogenesis;6.04301547150733e-07!GO:0000245;spliceosome assembly;9.23781666220086e-07!GO:0006916;anti-apoptosis;9.5652288047617e-07!GO:0003713;transcription coactivator activity;1.20258856636597e-06!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.31115420028459e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.34192157110549e-06!GO:0006261;DNA-dependent DNA replication;1.3579899782978e-06!GO:0006099;tricarboxylic acid cycle;1.43964353101695e-06!GO:0046356;acetyl-CoA catabolic process;1.43964353101695e-06!GO:0006334;nucleosome assembly;1.43964353101695e-06!GO:0045259;proton-transporting ATP synthase complex;1.50796111935386e-06!GO:0015630;microtubule cytoskeleton;1.52967357785208e-06!GO:0000151;ubiquitin ligase complex;1.69091451942098e-06!GO:0006752;group transfer coenzyme metabolic process;1.86613940694078e-06!GO:0045786;negative regulation of progression through cell cycle;2.06942905371742e-06!GO:0031497;chromatin assembly;2.43158707346217e-06!GO:0006888;ER to Golgi vesicle-mediated transport;2.76484649211786e-06!GO:0009117;nucleotide metabolic process;2.93372787023155e-06!GO:0005667;transcription factor complex;3.00904944434547e-06!GO:0009892;negative regulation of metabolic process;3.60601861480282e-06!GO:0016564;transcription repressor activity;3.66795740153159e-06!GO:0005813;centrosome;3.82508204327541e-06!GO:0005819;spindle;3.8486292667187e-06!GO:0051427;hormone receptor binding;4.32889440017998e-06!GO:0003724;RNA helicase activity;4.41991734782759e-06!GO:0016563;transcription activator activity;4.42158036555913e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;5.13941199209089e-06!GO:0006084;acetyl-CoA metabolic process;5.35917391645576e-06!GO:0006793;phosphorus metabolic process;6.37594434012784e-06!GO:0006796;phosphate metabolic process;6.37594434012784e-06!GO:0009967;positive regulation of signal transduction;6.60090478384127e-06!GO:0009109;coenzyme catabolic process;7.69242870935682e-06!GO:0005762;mitochondrial large ribosomal subunit;8.86516606521124e-06!GO:0000315;organellar large ribosomal subunit;8.86516606521124e-06!GO:0051329;interphase of mitotic cell cycle;9.15235534173328e-06!GO:0035257;nuclear hormone receptor binding;9.84785600597784e-06!GO:0007243;protein kinase cascade;1.03360930409988e-05!GO:0005525;GTP binding;1.25861637458547e-05!GO:0016481;negative regulation of transcription;1.26778775392139e-05!GO:0005815;microtubule organizing center;1.30019376928455e-05!GO:0051187;cofactor catabolic process;1.60073199142122e-05!GO:0006613;cotranslational protein targeting to membrane;1.71942898110282e-05!GO:0051168;nuclear export;1.7407265346903e-05!GO:0044440;endosomal part;1.86510792812033e-05!GO:0010008;endosome membrane;1.86510792812033e-05!GO:0042802;identical protein binding;1.96766525585152e-05!GO:0005770;late endosome;2.01456527136306e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.0162198177581e-05!GO:0016310;phosphorylation;2.21978512473015e-05!GO:0000314;organellar small ribosomal subunit;3.45190171305528e-05!GO:0005763;mitochondrial small ribosomal subunit;3.45190171305528e-05!GO:0008654;phospholipid biosynthetic process;3.7029292129334e-05!GO:0050789;regulation of biological process;4.01949726869181e-05!GO:0003682;chromatin binding;4.04711999679166e-05!GO:0003690;double-stranded DNA binding;4.23288705519055e-05!GO:0044431;Golgi apparatus part;6.48602828133e-05!GO:0003729;mRNA binding;6.48904448914457e-05!GO:0000079;regulation of cyclin-dependent protein kinase activity;7.00067029744109e-05!GO:0051325;interphase;7.2835761348924e-05!GO:0019843;rRNA binding;8.59068450310206e-05!GO:0048518;positive regulation of biological process;8.82482594659398e-05!GO:0043021;ribonucleoprotein binding;9.09024438656797e-05!GO:0016740;transferase activity;9.3028750364079e-05!GO:0000075;cell cycle checkpoint;9.88350542207854e-05!GO:0016491;oxidoreductase activity;0.000106828238848877!GO:0005798;Golgi-associated vesicle;0.000110158949258854!GO:0007051;spindle organization and biogenesis;0.000127860338610609!GO:0003714;transcription corepressor activity;0.000142831150503259!GO:0065009;regulation of a molecular function;0.000148372114908788!GO:0031988;membrane-bound vesicle;0.000158042136441818!GO:0005773;vacuole;0.00016900967585137!GO:0007088;regulation of mitosis;0.000169156484144373!GO:0006402;mRNA catabolic process;0.000174099953188553!GO:0008186;RNA-dependent ATPase activity;0.000180978416586203!GO:0045454;cell redox homeostasis;0.000183116506975654!GO:0032561;guanyl ribonucleotide binding;0.000197694000189506!GO:0019001;guanyl nucleotide binding;0.000197694000189506!GO:0016023;cytoplasmic membrane-bound vesicle;0.000210104444420303!GO:0005657;replication fork;0.000215783376918396!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000230039893297981!GO:0048471;perinuclear region of cytoplasm;0.000238518557682685!GO:0003899;DNA-directed RNA polymerase activity;0.00024241307711915!GO:0006950;response to stress;0.000264549050814715!GO:0000775;chromosome, pericentric region;0.000265848974605532!GO:0005769;early endosome;0.0002730677452461!GO:0043681;protein import into mitochondrion;0.000275115176092159!GO:0044452;nucleolar part;0.00029300332636453!GO:0003702;RNA polymerase II transcription factor activity;0.00029300332636453!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000293433516737704!GO:0006612;protein targeting to membrane;0.000317121220973388!GO:0045893;positive regulation of transcription, DNA-dependent;0.000335734701349754!GO:0000786;nucleosome;0.000336434427113513!GO:0030118;clathrin coat;0.000381586230573429!GO:0008094;DNA-dependent ATPase activity;0.000384913796863533!GO:0031252;leading edge;0.00039344094759892!GO:0008033;tRNA processing;0.000406406764846121!GO:0051789;response to protein stimulus;0.000447412997112256!GO:0006986;response to unfolded protein;0.000447412997112256!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000447412997112256!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000468487479264319!GO:0016853;isomerase activity;0.000512510626885315!GO:0004004;ATP-dependent RNA helicase activity;0.000517463626775354!GO:0000323;lytic vacuole;0.000524277467301716!GO:0005764;lysosome;0.000524277467301716!GO:0016363;nuclear matrix;0.000548874472346117!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000553677357168957!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000553677357168957!GO:0006302;double-strand break repair;0.000558557520927198!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000574828326806132!GO:0045941;positive regulation of transcription;0.00072310795755981!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000741841502766886!GO:0015399;primary active transmembrane transporter activity;0.000741841502766886!GO:0006626;protein targeting to mitochondrion;0.000752286614365818!GO:0007264;small GTPase mediated signal transduction;0.000785340053906863!GO:0006891;intra-Golgi vesicle-mediated transport;0.000785340053906863!GO:0000139;Golgi membrane;0.000785340053906863!GO:0031982;vesicle;0.000821379319949634!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000841996243704482!GO:0008361;regulation of cell size;0.000861895989226766!GO:0048468;cell development;0.000925316497160367!GO:0005048;signal sequence binding;0.00096884733904953!GO:0019222;regulation of metabolic process;0.00103329135670282!GO:0016197;endosome transport;0.00103329135670282!GO:0006352;transcription initiation;0.00103657109679607!GO:0030132;clathrin coat of coated pit;0.00103922935163396!GO:0030119;AP-type membrane coat adaptor complex;0.00103963155746185!GO:0019899;enzyme binding;0.00105271543041467!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00114211521448091!GO:0006401;RNA catabolic process;0.00114211521448091!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00114973550117325!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00114973550117325!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00114973550117325!GO:0051052;regulation of DNA metabolic process;0.00117767941861948!GO:0005885;Arp2/3 protein complex;0.00118706404864718!GO:0051252;regulation of RNA metabolic process;0.00118706404864718!GO:0031410;cytoplasmic vesicle;0.00119273389001949!GO:0008250;oligosaccharyl transferase complex;0.00122725969494297!GO:0031072;heat shock protein binding;0.00125270875889565!GO:0016251;general RNA polymerase II transcription factor activity;0.00135001762543303!GO:0006091;generation of precursor metabolites and energy;0.00142475182065215!GO:0043065;positive regulation of apoptosis;0.0014295547880165!GO:0033116;ER-Golgi intermediate compartment membrane;0.00144396906517686!GO:0005637;nuclear inner membrane;0.00150339316112255!GO:0006417;regulation of translation;0.00155631754543621!GO:0008632;apoptotic program;0.00164915431450915!GO:0000776;kinetochore;0.00167307711620035!GO:0005684;U2-dependent spliceosome;0.00170598441382004!GO:0016049;cell growth;0.00170599465127991!GO:0030131;clathrin adaptor complex;0.00171132280841275!GO:0046983;protein dimerization activity;0.00171312165581237!GO:0004576;oligosaccharyl transferase activity;0.00174283958515351!GO:0043068;positive regulation of programmed cell death;0.00179262557584355!GO:0045892;negative regulation of transcription, DNA-dependent;0.0018348861654046!GO:0032508;DNA duplex unwinding;0.0019077524470785!GO:0032392;DNA geometric change;0.0019077524470785!GO:0003678;DNA helicase activity;0.00191170667137182!GO:0009165;nucleotide biosynthetic process;0.00194343345256321!GO:0046474;glycerophospholipid biosynthetic process;0.0020344876790282!GO:0046966;thyroid hormone receptor binding;0.00212519669411647!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00223805179334265!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00223805179334265!GO:0019867;outer membrane;0.00226912793906098!GO:0051920;peroxiredoxin activity;0.00236106880180252!GO:0030880;RNA polymerase complex;0.00242057759946386!GO:0048500;signal recognition particle;0.00242391053870824!GO:0005788;endoplasmic reticulum lumen;0.00243243971701912!GO:0006414;translational elongation;0.00247713495365756!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0024910873673901!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00250345965917865!GO:0006405;RNA export from nucleus;0.00250345965917865!GO:0030663;COPI coated vesicle membrane;0.00255658868078823!GO:0030126;COPI vesicle coat;0.00255658868078823!GO:0008139;nuclear localization sequence binding;0.00258428795164064!GO:0031968;organelle outer membrane;0.00271379615592821!GO:0046489;phosphoinositide biosynthetic process;0.00272561502403945!GO:0030867;rough endoplasmic reticulum membrane;0.00278157065754858!GO:0015980;energy derivation by oxidation of organic compounds;0.0028992178736803!GO:0016859;cis-trans isomerase activity;0.00299848886567895!GO:0016126;sterol biosynthetic process;0.0031051982380897!GO:0018196;peptidyl-asparagine modification;0.00312800574064836!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00312800574064836!GO:0043414;biopolymer methylation;0.00312800574064836!GO:0001558;regulation of cell growth;0.00312800574064836!GO:0006268;DNA unwinding during replication;0.00313404025218753!GO:0050790;regulation of catalytic activity;0.00317439367576598!GO:0043488;regulation of mRNA stability;0.00328137156608252!GO:0043487;regulation of RNA stability;0.00328137156608252!GO:0030133;transport vesicle;0.00336815604604689!GO:0007006;mitochondrial membrane organization and biogenesis;0.00338775919579115!GO:0000082;G1/S transition of mitotic cell cycle;0.00387521800437119!GO:0000059;protein import into nucleus, docking;0.00424320396226703!GO:0051087;chaperone binding;0.00427843571818111!GO:0005741;mitochondrial outer membrane;0.00431894548978931!GO:0007093;mitotic cell cycle checkpoint;0.00431894548978931!GO:0008312;7S RNA binding;0.00436276960670898!GO:0030658;transport vesicle membrane;0.00439777503676379!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00447938395250524!GO:0003684;damaged DNA binding;0.00452222615806987!GO:0043492;ATPase activity, coupled to movement of substances;0.00457785509059657!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00459350923983169!GO:0003711;transcription elongation regulator activity;0.00459741689029519!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00476194756800245!GO:0000428;DNA-directed RNA polymerase complex;0.00476194756800245!GO:0030137;COPI-coated vesicle;0.00484328271711303!GO:0043624;cellular protein complex disassembly;0.00495443398065418!GO:0006611;protein export from nucleus;0.00528499759095031!GO:0004527;exonuclease activity;0.00530379382101296!GO:0030176;integral to endoplasmic reticulum membrane;0.00546107916388336!GO:0046467;membrane lipid biosynthetic process;0.00547780777471042!GO:0006818;hydrogen transport;0.00549543153502191!GO:0015992;proton transport;0.00553378506165745!GO:0006338;chromatin remodeling;0.00560349584892639!GO:0016272;prefoldin complex;0.00560349584892639!GO:0000049;tRNA binding;0.00566952242993779!GO:0006979;response to oxidative stress;0.00568288049387585!GO:0035258;steroid hormone receptor binding;0.00586726037409586!GO:0032984;macromolecular complex disassembly;0.00588398100753414!GO:0006650;glycerophospholipid metabolic process;0.00591354652763117!GO:0006383;transcription from RNA polymerase III promoter;0.00597111183190308!GO:0019752;carboxylic acid metabolic process;0.00612503558897199!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00613330381110029!GO:0005869;dynactin complex;0.0061559437884275!GO:0030036;actin cytoskeleton organization and biogenesis;0.00621499584670063!GO:0022890;inorganic cation transmembrane transporter activity;0.00630958645875245!GO:0046483;heterocycle metabolic process;0.00646478655493135!GO:0031326;regulation of cellular biosynthetic process;0.00650580689617961!GO:0043022;ribosome binding;0.00656795922991172!GO:0007010;cytoskeleton organization and biogenesis;0.00669702142499154!GO:0007052;mitotic spindle organization and biogenesis;0.00674394604885113!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00674394604885113!GO:0045047;protein targeting to ER;0.00674394604885113!GO:0005791;rough endoplasmic reticulum;0.00676545842594477!GO:0006275;regulation of DNA replication;0.00676545842594477!GO:0006310;DNA recombination;0.00726459140930451!GO:0006839;mitochondrial transport;0.00730511656825726!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00771463161908458!GO:0006082;organic acid metabolic process;0.0077308775575595!GO:0015631;tubulin binding;0.00777791375484127!GO:0032259;methylation;0.00783124104311362!GO:0008022;protein C-terminus binding;0.00793673251473714!GO:0008283;cell proliferation;0.00793673251473714!GO:0008610;lipid biosynthetic process;0.00820577023958491!GO:0030125;clathrin vesicle coat;0.00831492667149109!GO:0030665;clathrin coated vesicle membrane;0.00831492667149109!GO:0065007;biological regulation;0.00831492667149109!GO:0050662;coenzyme binding;0.00854523331006161!GO:0000792;heterochromatin;0.00861835702920415!GO:0016044;membrane organization and biogenesis;0.00866328950952321!GO:0005876;spindle microtubule;0.00879811847518544!GO:0006520;amino acid metabolic process;0.0092608193698385!GO:0005856;cytoskeleton;0.00946607480144109!GO:0030384;phosphoinositide metabolic process;0.00952883052803481!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00953537728793943!GO:0008637;apoptotic mitochondrial changes;0.00968464290123062!GO:0051338;regulation of transferase activity;0.00991102281139693!GO:0043241;protein complex disassembly;0.00991102281139693!GO:0007059;chromosome segregation;0.0100414703213823!GO:0009889;regulation of biosynthetic process;0.0104036211813278!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0105764821816821!GO:0006376;mRNA splice site selection;0.0106044604410645!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0106044604410645!GO:0048487;beta-tubulin binding;0.0106713265446576!GO:0006917;induction of apoptosis;0.0107099765602291!GO:0051287;NAD binding;0.0107191140886651!GO:0003725;double-stranded RNA binding;0.0109393821576059!GO:0030660;Golgi-associated vesicle membrane;0.0109704232011356!GO:0045792;negative regulation of cell size;0.0112627116736918!GO:0040029;regulation of gene expression, epigenetic;0.0114517981105158!GO:0051059;NF-kappaB binding;0.0115112979166744!GO:0005905;coated pit;0.0115184199574901!GO:0008234;cysteine-type peptidase activity;0.0116509346102853!GO:0031124;mRNA 3'-end processing;0.0120857962989376!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0120857962989376!GO:0015002;heme-copper terminal oxidase activity;0.0120857962989376!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0120857962989376!GO:0004129;cytochrome-c oxidase activity;0.0120857962989376!GO:0008168;methyltransferase activity;0.0121929743540245!GO:0009112;nucleobase metabolic process;0.0131032639448654!GO:0031529;ruffle organization and biogenesis;0.0132528904053391!GO:0006607;NLS-bearing substrate import into nucleus;0.0132978012179178!GO:0007034;vacuolar transport;0.0133547364346578!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0134174097990749!GO:0012502;induction of programmed cell death;0.0139441526842909!GO:0006354;RNA elongation;0.0143396821622859!GO:0045045;secretory pathway;0.0143396821622859!GO:0045936;negative regulation of phosphate metabolic process;0.0143396821622859!GO:0016741;transferase activity, transferring one-carbon groups;0.014481431681579!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0145488266595727!GO:0030308;negative regulation of cell growth;0.0152926826170903!GO:0009116;nucleoside metabolic process;0.015359246823889!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.015359246823889!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0155868385176851!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0158691580871379!GO:0005774;vacuolar membrane;0.0158691580871379!GO:0007040;lysosome organization and biogenesis;0.0163618270193192!GO:0022411;cellular component disassembly;0.016823993856845!GO:0030521;androgen receptor signaling pathway;0.0173586597482758!GO:0051098;regulation of binding;0.0174191233758491!GO:0030027;lamellipodium;0.0174191233758491!GO:0006289;nucleotide-excision repair;0.0178198047523887!GO:0006892;post-Golgi vesicle-mediated transport;0.0179111343392241!GO:0003746;translation elongation factor activity;0.0179111343392241!GO:0031323;regulation of cellular metabolic process;0.0183693411346189!GO:0000209;protein polyubiquitination;0.0189950410194945!GO:0051101;regulation of DNA binding;0.019162181753649!GO:0009893;positive regulation of metabolic process;0.0191958471445401!GO:0006695;cholesterol biosynthetic process;0.0193235769011441!GO:0016584;nucleosome positioning;0.0194567110476453!GO:0043549;regulation of kinase activity;0.0194719550571546!GO:0005832;chaperonin-containing T-complex;0.0198341391097577!GO:0048146;positive regulation of fibroblast proliferation;0.0202254599735633!GO:0005669;transcription factor TFIID complex;0.0204564287330555!GO:0007050;cell cycle arrest;0.0206168659086745!GO:0000086;G2/M transition of mitotic cell cycle;0.0207698922210469!GO:0046982;protein heterodimerization activity;0.0208033001040582!GO:0030518;steroid hormone receptor signaling pathway;0.0212186847707759!GO:0000339;RNA cap binding;0.0212286567571033!GO:0043596;nuclear replication fork;0.021290201956746!GO:0050178;phenylpyruvate tautomerase activity;0.0213795365904038!GO:0031901;early endosome membrane;0.0216474834441884!GO:0031625;ubiquitin protein ligase binding;0.0217227486537699!GO:0006730;one-carbon compound metabolic process;0.0217896260005158!GO:0030503;regulation of cell redox homeostasis;0.0228791030688455!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0229260852541951!GO:0004674;protein serine/threonine kinase activity;0.0231336576962694!GO:0030659;cytoplasmic vesicle membrane;0.0231427838853511!GO:0030029;actin filament-based process;0.0233143290993749!GO:0048144;fibroblast proliferation;0.0233558018758191!GO:0048145;regulation of fibroblast proliferation;0.0233558018758191!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0236942204190879!GO:0017166;vinculin binding;0.0236942204190879!GO:0008180;signalosome;0.0236942204190879!GO:0030134;ER to Golgi transport vesicle;0.0237643842506188!GO:0006378;mRNA polyadenylation;0.0240520767506194!GO:0006368;RNA elongation from RNA polymerase II promoter;0.024327864186292!GO:0000178;exosome (RNase complex);0.024327864186292!GO:0001836;release of cytochrome c from mitochondria;0.0243673241282885!GO:0051540;metal cluster binding;0.0243673241282885!GO:0051536;iron-sulfur cluster binding;0.0243673241282885!GO:0001726;ruffle;0.0246110700737554!GO:0046822;regulation of nucleocytoplasmic transport;0.0250279064067964!GO:0008629;induction of apoptosis by intracellular signals;0.0252938032631642!GO:0000096;sulfur amino acid metabolic process;0.0257014873146334!GO:0000922;spindle pole;0.0257467246609813!GO:0008538;proteasome activator activity;0.0257487343402401!GO:0022415;viral reproductive process;0.025759619571615!GO:0005862;muscle thin filament tropomyosin;0.0260076662385833!GO:0007033;vacuole organization and biogenesis;0.0260730594256933!GO:0043154;negative regulation of caspase activity;0.0261364787109666!GO:0042393;histone binding;0.0262162360978142!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0265640478817761!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0266158547572891!GO:0045926;negative regulation of growth;0.0270355722350015!GO:0004003;ATP-dependent DNA helicase activity;0.027120747213175!GO:0008097;5S rRNA binding;0.0272204818811154!GO:0031902;late endosome membrane;0.0276979863853574!GO:0030032;lamellipodium biogenesis;0.0282968138298057!GO:0047485;protein N-terminus binding;0.0285766403013185!GO:0006733;oxidoreduction coenzyme metabolic process;0.0292818929210148!GO:0006144;purine base metabolic process;0.0296018163283339!GO:0022406;membrane docking;0.0302990125754327!GO:0048278;vesicle docking;0.0302990125754327!GO:0045859;regulation of protein kinase activity;0.0302990125754327!GO:0040008;regulation of growth;0.030342708799698!GO:0030031;cell projection biogenesis;0.0307545556023756!GO:0042326;negative regulation of phosphorylation;0.0310669658800068!GO:0016125;sterol metabolic process;0.0314124089467401!GO:0033673;negative regulation of kinase activity;0.0317151528724446!GO:0006469;negative regulation of protein kinase activity;0.0317151528724446!GO:0006509;membrane protein ectodomain proteolysis;0.0321398486271369!GO:0033619;membrane protein proteolysis;0.0321398486271369!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0322828390784463!GO:0044437;vacuolar part;0.0322828390784463!GO:0006284;base-excision repair;0.0322912746025149!GO:0009615;response to virus;0.0324928536875646!GO:0006506;GPI anchor biosynthetic process;0.0329994879048671!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0329994879048671!GO:0010257;NADH dehydrogenase complex assembly;0.0329994879048671!GO:0033108;mitochondrial respiratory chain complex assembly;0.0329994879048671!GO:0007242;intracellular signaling cascade;0.0331791348871621!GO:0007041;lysosomal transport;0.0332527498316443!GO:0048037;cofactor binding;0.0332993417156617!GO:0030127;COPII vesicle coat;0.0343321933881384!GO:0012507;ER to Golgi transport vesicle membrane;0.0343321933881384!GO:0001952;regulation of cell-matrix adhesion;0.0349126445151505!GO:0006767;water-soluble vitamin metabolic process;0.0350101581043239!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0350222661847839!GO:0004518;nuclease activity;0.0351814643851989!GO:0008426;protein kinase C inhibitor activity;0.0355601938545662!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.035726992098532!GO:0031123;RNA 3'-end processing;0.0357573949424133!GO:0030128;clathrin coat of endocytic vesicle;0.0359033980656673!GO:0030669;clathrin-coated endocytic vesicle membrane;0.0359033980656673!GO:0030122;AP-2 adaptor complex;0.0359033980656673!GO:0006672;ceramide metabolic process;0.0364139047154162!GO:0006505;GPI anchor metabolic process;0.0366502563025508!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0366502563025508!GO:0006740;NADPH regeneration;0.0366502563025508!GO:0006098;pentose-phosphate shunt;0.0366502563025508!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0378819048907358!GO:0006643;membrane lipid metabolic process;0.0383258814606987!GO:0022408;negative regulation of cell-cell adhesion;0.0383956081657824!GO:0031371;ubiquitin conjugating enzyme complex;0.0388964577145942!GO:0001889;liver development;0.0394629427372253!GO:0051348;negative regulation of transferase activity;0.039670629700062!GO:0045334;clathrin-coated endocytic vesicle;0.039911027370841!GO:0043284;biopolymer biosynthetic process;0.0408290306056929!GO:0005758;mitochondrial intermembrane space;0.0408867502568009!GO:0005874;microtubule;0.0414459868670159!GO:0050811;GABA receptor binding;0.0425094472900879!GO:0006497;protein amino acid lipidation;0.0430764153577626!GO:0007004;telomere maintenance via telomerase;0.04329578903028!GO:0004532;exoribonuclease activity;0.0437303584186353!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0437303584186353!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0441535500816267!GO:0044433;cytoplasmic vesicle part;0.044443466770446!GO:0008243;plasminogen activator activity;0.0449016049203992!GO:0017134;fibroblast growth factor binding;0.0449016049203992!GO:0006595;polyamine metabolic process;0.045032960620792!GO:0031532;actin cytoskeleton reorganization;0.0453845278763121!GO:0042770;DNA damage response, signal transduction;0.0462081119298831!GO:0008047;enzyme activator activity;0.0466291634415514!GO:0035035;histone acetyltransferase binding;0.0473141769815415!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0479704834895172!GO:0005784;translocon complex;0.0480574368936738!GO:0006904;vesicle docking during exocytosis;0.0482189079845295!GO:0030911;TPR domain binding;0.0482189079845295!GO:0046519;sphingoid metabolic process;0.0483796402882296!GO:0008092;cytoskeletal protein binding;0.0485169993063649!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0485170596415984!GO:0051539;4 iron, 4 sulfur cluster binding;0.0488950645007086!GO:0043331;response to dsRNA;0.0490072546996636!GO:0008408;3'-5' exonuclease activity;0.0492357847241231!GO:0031325;positive regulation of cellular metabolic process;0.049301252378647!GO:0032200;telomere organization and biogenesis;0.0493584554153388!GO:0000723;telomere maintenance;0.0493584554153388!GO:0004192;cathepsin D activity;0.049700964381411!GO:0043601;nuclear replisome;0.0497246242085644!GO:0030894;replisome;0.0497246242085644 | |||
|sample_id=10545 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=tongue | |||
|top_motifs=ZEB1:1.72497826563;SNAI1..3:1.6507535956;TP53:1.56582753291;VSX1,2:1.51164096846;TBX4,5:1.43563090051;ONECUT1,2:1.33252792039;RBPJ:1.31278096757;NR6A1:1.30217618515;FOXM1:1.26196535304;IRF7:1.21367833464;CDX1,2,4:1.15875414357;PAX4:1.13521842663;ZBTB16:1.05728055331;FOXQ1:1.00221691918;ARID5B:0.978549809088;PPARG:0.914963570882;FOXD3:0.909021069794;PAX6:0.892458540508;NKX2-1,4:0.892260550795;UFEwm:0.868376581818;PAX1,9:0.826902444008;GCM1,2:0.814316808508;MYOD1:0.797423067244;PITX1..3:0.79684595157;HOXA9_MEIS1:0.788425969822;ZIC1..3:0.785209412841;E2F1..5:0.745382691154;bHLH_family:0.74031459123;ADNP_IRX_SIX_ZHX:0.722363737245;NKX2-2,8:0.714467992988;POU2F1..3:0.689780455998;NKX2-3_NKX2-5:0.678940697504;AIRE:0.66302334529;TOPORS:0.646890270054;TEAD1:0.641139906368;PDX1:0.631464549637;OCT4_SOX2{dimer}:0.53117362696;RXR{A,B,G}:0.509602446108;SMAD1..7,9:0.491464578709;NKX6-1,2:0.489064087941;ESRRA:0.476992713019;STAT5{A,B}:0.438737450161;CDC5L:0.422693399535;YY1:0.420347346293;IRF1,2:0.418196601267;GATA4:0.416251879794;NFIL3:0.410682783608;ZNF384:0.404000949745;KLF4:0.385722488832;FOXO1,3,4:0.347695998961;FOS_FOS{B,L1}_JUN{B,D}:0.3460341591;ZBTB6:0.345143355093;RFX2..5_RFXANK_RFXAP:0.327417868612;TFDP1:0.304852446393;IKZF1:0.29036665216;FOX{I1,J2}:0.288863176158;ELK1,4_GABP{A,B1}:0.268524081433;TEF:0.264736365649;GZF1:0.255252289252;GLI1..3:0.251766849103;HSF1,2:0.236965880094;TBP:0.225974834481;HMX1:0.215989663872;POU6F1:0.188224197909;BACH2:0.177045572105;HOX{A4,D4}:0.142131456654;NR5A1,2:0.138839146235;HAND1,2:0.109067454878;POU1F1:0.10613307545;HLF:0.0825364059776;PAX2:0.06737734928;LHX3,4:0.0663123279532;ZNF423:0.0556907506511;MTF1:0.0449449766831;TLX1..3_NFIC{dimer}:0.0324843799534;HNF4A_NR2F1,2:0.0266482660962;NFIX:0.0212395912351;FOXP3:-0.00705525966111;CUX2:-0.0236399382334;MAFB:-0.0258508892584;FOXN1:-0.0274322472895;PRDM1:-0.0489879265331;TFAP2{A,C}:-0.0597081970303;ALX1:-0.0601875113862;NKX3-1:-0.0676784461675;NFE2:-0.0798303233645;MYB:-0.0892400717166;NR1H4:-0.0930648014935;FOSL2:-0.102968356902;CEBPA,B_DDIT3:-0.111868539117;SOX17:-0.127429438622;ALX4:-0.129256911007;EP300:-0.131718232993;NFKB1_REL_RELA:-0.134946931901;IKZF2:-0.151314323817;GFI1B:-0.156263813045;XCPE1{core}:-0.163448827604;ZNF148:-0.165912392548;MED-1{core}:-0.18187392514;ZNF143:-0.190451543106;T:-0.1912194093;PAX3,7:-0.202914407002;ESR1:-0.204509804279;HNF1A:-0.208256259904;FOX{F1,F2,J1}:-0.220175759031;ELF1,2,4:-0.248023401907;TAL1_TCF{3,4,12}:-0.24946072098;AR:-0.250016587196;TFCP2:-0.256036247816;LEF1_TCF7_TCF7L1,2:-0.260669809496;GFI1:-0.266687117363;MAZ:-0.274335157295;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.277336749041;EVI1:-0.277827996617;RREB1:-0.281546185655;BPTF:-0.293400304671;NFY{A,B,C}:-0.304924495253;STAT2,4,6:-0.332320722585;FOXP1:-0.347744889197;GTF2I:-0.353981471075;LMO2:-0.357247227841;ATF5_CREB3:-0.360111073547;TLX2:-0.363263276434;SOX{8,9,10}:-0.368592774382;NR3C1:-0.392204724672;ATF4:-0.400054834252;ZNF238:-0.413306562345;MYFfamily:-0.414430416192;MZF1:-0.418590218035;HOX{A5,B5}:-0.433235987165;NANOG:-0.437757770833;HIF1A:-0.43926859655;SOX2:-0.452929252503;NFE2L2:-0.457107869596;SPIB:-0.458442306642;NRF1:-0.465288655145;ETS1,2:-0.467525217559;NKX3-2:-0.469302069572;SREBF1,2:-0.472290412106;CRX:-0.478153701782;SPI1:-0.479458409623;NFE2L1:-0.489958437832;PBX1:-0.501004418111;RFX1:-0.504235540346;REST:-0.509440011635;BREu{core}:-0.528508674896;FOX{D1,D2}:-0.534241738916;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.555385237645;POU5F1:-0.564477320124;POU3F1..4:-0.572811046369;MYBL2:-0.576072584059;GATA6:-0.581303244372;EBF1:-0.58726503116;ZFP161:-0.601812316559;PAX8:-0.615395004669;RUNX1..3:-0.62931015045;RORA:-0.646843057201;ATF2:-0.653584675097;EGR1..3:-0.656113185261;MEF2{A,B,C,D}:-0.678103456376;HES1:-0.684097615727;AHR_ARNT_ARNT2:-0.684109917275;HOX{A6,A7,B6,B7}:-0.685816274527;SP1:-0.700481166053;GTF2A1,2:-0.714475321435;EN1,2:-0.740234667044;PRRX1,2:-0.758958305885;SOX5:-0.784313849607;FOXA2:-0.789822848367;HMGA1,2:-0.807167264936;TGIF1:-0.831431091017;HIC1:-0.841493295574;DMAP1_NCOR{1,2}_SMARC:-0.864716075032;PATZ1:-0.886503042106;NHLH1,2:-0.892631671059;RXRA_VDR{dimer}:-0.900418398226;MTE{core}:-0.905765449535;TFAP2B:-0.916570618955;SRF:-0.932949416925;CREB1:-0.944688830366;TFAP4:-0.951199607848;PAX5:-0.971755977647;XBP1:-0.99868414237;FOXL1:-1.03791535276;JUN:-1.03827667373;DBP:-1.09374427176;SPZ1:-1.20126956009;NFATC1..3:-1.21297841589;STAT1,3:-1.2726291975;ATF6:-1.51677820935;NANOG{mouse}:-1.53409897422;HBP1_HMGB_SSRP1_UBTF:-1.56806652161 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10545-107H5;search_select_hide=table117:FF:10545-107H5 | |||
}} | }} |
Latest revision as of 14:28, 3 June 2020
Name: | oral squamous cell carcinoma cell line:HSC-3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11717 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11717
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11717
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.159 |
10 | 10 | 0.148 |
100 | 100 | 0.23 |
101 | 101 | 0.641 |
102 | 102 | 0.297 |
103 | 103 | 0.0862 |
104 | 104 | 0.605 |
105 | 105 | 0.587 |
106 | 106 | 0.0251 |
107 | 107 | 0.00702 |
108 | 108 | 0.191 |
109 | 109 | 0.0153 |
11 | 11 | 0.224 |
110 | 110 | 0.0337 |
111 | 111 | 0.628 |
112 | 112 | 0.0708 |
113 | 113 | 0.104 |
114 | 114 | 0.0917 |
115 | 115 | 0.753 |
116 | 116 | 0.572 |
117 | 117 | 0.0213 |
118 | 118 | 0.312 |
119 | 119 | 0.264 |
12 | 12 | 0.182 |
120 | 120 | 0.0246 |
121 | 121 | 0.402 |
122 | 122 | 0.965 |
123 | 123 | 0.447 |
124 | 124 | 0.0793 |
125 | 125 | 0.418 |
126 | 126 | 0.551 |
127 | 127 | 0.654 |
128 | 128 | 0.568 |
129 | 129 | 0.087 |
13 | 13 | 0.0442 |
130 | 130 | 0.972 |
131 | 131 | 0.251 |
132 | 132 | 0.308 |
133 | 133 | 0.024 |
134 | 134 | 0.0157 |
135 | 135 | 0.89 |
136 | 136 | 0.133 |
137 | 137 | 0.227 |
138 | 138 | 0.0304 |
139 | 139 | 0.862 |
14 | 14 | 0.906 |
140 | 140 | 0.934 |
141 | 141 | 0.0455 |
142 | 142 | 0.93 |
143 | 143 | 0.0531 |
144 | 144 | 0.96 |
145 | 145 | 0.152 |
146 | 146 | 0.57 |
147 | 147 | 0.434 |
148 | 148 | 0.868 |
149 | 149 | 0.203 |
15 | 15 | 0.489 |
150 | 150 | 0.279 |
151 | 151 | 0.408 |
152 | 152 | 0.463 |
153 | 153 | 0.947 |
154 | 154 | 0.988 |
155 | 155 | 0.49 |
156 | 156 | 0.701 |
157 | 157 | 0.875 |
158 | 158 | 0.25 |
159 | 159 | 0.625 |
16 | 16 | 0.0249 |
160 | 160 | 0.0885 |
161 | 161 | 0.0591 |
162 | 162 | 0.159 |
163 | 163 | 0.717 |
164 | 164 | 0.0877 |
165 | 165 | 0.0941 |
166 | 166 | 0.66 |
167 | 167 | 0.152 |
168 | 168 | 0.171 |
169 | 169 | 0.0119 |
17 | 17 | 0.102 |
18 | 18 | 0.235 |
19 | 19 | 0.683 |
2 | 2 | 0.267 |
20 | 20 | 0.998 |
21 | 21 | 0.11 |
22 | 22 | 0.803 |
23 | 23 | 0.775 |
24 | 24 | 0.0783 |
25 | 25 | 0.455 |
26 | 26 | 0.182 |
27 | 27 | 0.531 |
28 | 28 | 0.496 |
29 | 29 | 0.0332 |
3 | 3 | 0.205 |
30 | 30 | 0.596 |
31 | 31 | 0.758 |
32 | 32 | 0.605 |
33 | 33 | 0.219 |
34 | 34 | 0.469 |
35 | 35 | 0.431 |
36 | 36 | 0.581 |
37 | 37 | 0.52 |
38 | 38 | 0.354 |
39 | 39 | 0.586 |
4 | 4 | 0.973 |
40 | 40 | 0.351 |
41 | 41 | 0.273 |
42 | 42 | 0.539 |
43 | 43 | 0.477 |
44 | 44 | 0.00292 |
45 | 45 | 0.372 |
46 | 46 | 0.0865 |
47 | 47 | 0.138 |
48 | 48 | 0.175 |
49 | 49 | 0.79 |
5 | 5 | 0.832 |
50 | 50 | 0.778 |
51 | 51 | 0.604 |
52 | 52 | 0.364 |
53 | 53 | 0.889 |
54 | 54 | 0.675 |
55 | 55 | 0.167 |
56 | 56 | 0.418 |
57 | 57 | 0.0425 |
58 | 58 | 0.277 |
59 | 59 | 0.125 |
6 | 6 | 0.783 |
60 | 60 | 0.0731 |
61 | 61 | 0.914 |
62 | 62 | 0.273 |
63 | 63 | 0.191 |
64 | 64 | 0.396 |
65 | 65 | 0.326 |
66 | 66 | 0.836 |
67 | 67 | 0.728 |
68 | 68 | 0.127 |
69 | 69 | 0.137 |
7 | 7 | 0.161 |
70 | 70 | 0.024 |
71 | 71 | 0.0197 |
72 | 72 | 0.444 |
73 | 73 | 0.407 |
74 | 74 | 0.274 |
75 | 75 | 0.0516 |
76 | 76 | 0.491 |
77 | 77 | 0.225 |
78 | 78 | 0.0112 |
79 | 79 | 0.644 |
8 | 8 | 0.119 |
80 | 80 | 0.061 |
81 | 81 | 0.384 |
82 | 82 | 0.942 |
83 | 83 | 0.708 |
84 | 84 | 0.257 |
85 | 85 | 0.619 |
86 | 86 | 0.344 |
87 | 87 | 0.0839 |
88 | 88 | 0.431 |
89 | 89 | 0.0371 |
9 | 9 | 0.713 |
90 | 90 | 0.74 |
91 | 91 | 0.708 |
92 | 92 | 0.42 |
93 | 93 | 0.542 |
94 | 94 | 0.913 |
95 | 95 | 0.63 |
96 | 96 | 0.891 |
97 | 97 | 0.94 |
98 | 98 | 0.953 |
99 | 99 | 0.309 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11717
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0102025 HSC-3 cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000076 (squamous epithelial cell)
0000255 (eukaryotic cell)
0002076 (endo-epithelial cell)
0002251 (epithelial cell of alimentary canal)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
7 (disease of anatomical entity)
305 (carcinoma)
1749 (squamous cell carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0003343 (mucosa of oral region)
0000033 (head)
0000974 (neck)
0001007 (digestive system)
0000344 (mucosa)
0004121 (ectoderm-derived structure)
0000064 (organ part)
0004119 (endoderm-derived structure)
0000062 (organ)
0004111 (anatomical conduit)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000481 (multi-tissue structure)
0004923 (organ component layer)
0000161 (orifice)
0001444 (subdivision of head)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0004785 (respiratory system mucosa)
0003729 (mouth mucosa)
0010317 (germ layer / neural crest derived structure)
0001555 (digestive tract)
0001004 (respiratory system)
0000153 (anterior region of body)
0007811 (craniocervical region)
0000165 (mouth)
0000166 (oral opening)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0102024 (squamous cell carcinoma cell line sample)
0101120 (epithelial cell line sample)
0102211 (oral squamous cell carcinoma cell line sample)
0102027 (oral cancer cell line sample)
0102709 (head and neck squamous cell carcinoma cell line sample)
0102025 (HSC-3 cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000223 (endodermal cell)
UBERON:0002532 (epiblast (generic))
UBERON:0006601 (presumptive ectoderm)
UBERON:0006595 (presumptive endoderm)
UBERON:0010316 (germ layer / neural crest)