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Coexpression cluster:C1783

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Full id: C1783_alveolar_nonsmall_ductus_spinal_seminal_epididymis_somatostatinoma



Phase1 CAGE Peaks

Hg19::chr17:46690197..46690210,-p@chr17:46690197..46690210
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Hg19::chr17:46692457..46692484,-p2@HOXB8
Hg19::chr17:46692582..46692589,-p14@HOXB8
Hg19::chr17:46692603..46692621,-p6@HOXB8
Hg19::chr17:46692624..46692659,-p3@HOXB8


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
cavitated compound organ9.42e-2731
excretory tube1.88e-2016
kidney epithelium1.88e-2016
kidney1.56e-1926
kidney mesenchyme1.56e-1926
upper urinary tract1.56e-1926
kidney rudiment1.56e-1926
kidney field1.56e-1926
nephron epithelium1.07e-1815
renal tubule1.07e-1815
nephron tubule1.07e-1815
nephron1.07e-1815
uriniferous tubule1.07e-1815
nephrogenic mesenchyme1.07e-1815
nephron tubule epithelium5.45e-1810
abdominal segment of trunk2.40e-1660
abdomen2.40e-1660
cortex of kidney1.01e-1312
renal parenchyma1.01e-1312
renal system1.00e-1248
abdomen element4.85e-1254
abdominal segment element4.85e-1254
urinary system structure8.38e-1247
cortex1.79e-1015
parenchyma1.79e-1015
trunk region element2.90e-10101
subdivision of trunk5.64e-10112
body cavity precursor1.93e-0954
mesonephros2.21e-099
pronephros2.21e-099
nephrogenic cord2.21e-099
pronephric mesoderm2.21e-099
rostral part of nephrogenic cord2.21e-099
presumptive pronephric mesoderm2.21e-099
intervertebral cartilage1.31e-085
symphysis1.31e-085
nonsynovial joint1.31e-085
fibrous joint1.31e-085
cartilaginous joint1.31e-085
developing mesenchymal condensation1.31e-085
pre-cartilage condensation1.31e-085
cartilaginous condensation1.31e-085
cartilage element1.31e-085
post-cranial axial skeletal system1.31e-085
vertebral column1.31e-085
intervertebral disk1.31e-085
intervertebral joint1.31e-085
compound organ2.09e-0868
intraembryonic coelom2.30e-0812
mesonephric epithelium7.98e-088
mesonephric tubule7.98e-088
nephric duct7.98e-088
renal duct7.98e-088
mesonephric duct7.98e-088
pronephric duct7.98e-088
anatomical cavity1.02e-0761
urogenital ridge1.97e-0711
articulation2.03e-078
skeletal joint2.03e-078
articular system2.03e-078
omentum2.88e-076
peritoneum2.88e-076
abdominal cavity2.88e-076
visceral peritoneum2.88e-076
spinal cord3.99e-073
dorsal region element3.99e-073
dorsum3.99e-073
male genital duct4.92e-073
internal male genitalia4.92e-073
trunk5.34e-07199
mesenchyme5.72e-07160
entire embryonic mesenchyme5.72e-07160


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
SUZ12#23512550.11578091106293.15480790456198e-092.62120113559705e-07



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.