FF:10455-106G5: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00004774 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003 | |accession_numbers=CAGE;DRX007797;DRR008669;DRZ000094;DRZ001479;DRZ011444;DRZ012829 | ||
|ancestors_in_anatomy_facet= | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000738,CL:0002087,CL:0002242,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:12603 | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:12603 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0102144,FF:0101035,FF:0100741,FF:0100773,FF:0100739 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
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| |expression_enrichment_score=chr19:50922187..50922204,+!p1@SPIB!2.77!588.25!SPIB;;chr6:391743..391759,+!p1@IRF4!2.31!200.85!IRF4;;chr2:68592406..68592424,+!p1@PLEK!2.15!140.65!PLEK;;chr11:111249993..111250006,-!p1@POU2AF1!2.02!104.79!POU2AF1;;chr2:231090471..231090504,+!p2@SP140!1.83!66.33!SP140;;chr2:231090433..231090469,+!p1@SP140!1.80!62.06!SP140;;chr16:85932760..85932775,+!p1@IRF8!1.77!57.41!IRF8;;chr19:19281060..19281078,-!p2@MEF2BNB-MEF2B,p2@MEF2B!1.75!55.00!MEF2B;;chr17:38020392..38020477,-!p1@IKZF3!1.73!52.95!IKZF3;;chr2:185463247..185463263,+!p1@ZNF804A!1.70!85.47!ZNF804A;;chr11:47400078..47400106,-!p1@SPI1!1.70!49.05!SPI1;;chr3:189349162..189349207,+!p2@TP63!1.65!43.29!TP63;;chr7:115799942..115799955,-!p5@TFEC!1.58!36.60!TFEC;;chr19:36391434..36391450,-!p1@NFKBID!1.57!69.12!NFKBID;;chr7:50343634..50343717,+!p2@IKZF1!1.55!34.19!IKZF1;;chr2:100759010..100759035,-!p1@AFF3!1.51!31.21!AFF3;;chr18:52989031..52989079,-!p2@TCF4!1.49!68.93!TCF4;;chr15:57511609..57511651,+!p2@TCF12!1.43!42.92!TCF12;;chr2:100759037..100759058,-!p2@AFF3!1.42!25.46!AFF3;;chr14:75988771..75988826,+!p1@BATF!1.40!31.77!BATF;;chr7:50348268..50348366,+!p4@IKZF1!1.40!24.15!IKZF1;;chr1:167298300..167298319,+!p2@POU2F1!1.40!23.97!POU2F1;;chr2:68592394..68592405,+!p2@PLEK!1.37!22.30!PLEK;;chr20:42295745..42295765,+!p1@MYBL2!1.36!346.34!MYBL2;;chr7:64126535..64126559,+!p2@ZNF107!1.34!44.22!ZNF107;;chr3:101546827..101546847,+!p2@NFKBIZ!1.32!27.68!NFKBIZ;;chr5:134369905..134369972,-!p1@PITX1!1.28!27.31!PITX1;;chr7:50344251..50344288,+!p3@IKZF1!1.28!18.21!IKZF1;;chr19:42636586..42636607,-!p1@POU2F2!1.25!45.52!POU2F2;;chr2:60778035..60778060,-!p4@BCL11A!1.25!20.25!BCL11A;;chrX:131623026..131623039,-!p5@MBNL3!1.22!15.61!MBNL3;;chr2:60780607..60780624,-!p2@BCL11A!1.21!45.89!BCL11A;;chr1:23857698..23857733,-!p1@E2F2!1.21!28.06!E2F2;;chr19:50432453..50432468,+!p1@ATF5!1.20!822.74!ATF5;;chr2:60780753..60780800,-!p1@BCL11A!1.19!71.16!BCL11A;;chr20:42295713..42295738,+!p2@MYBL2!1.17!80.08!MYBL2;;chr17:41623692..41623715,-!p1@ETV4!1.15!56.30!ETV4;;chr6:135502408..135502459,+!p2@MYB!1.14!15.05!MYB;;chr13:41593425..41593480,-!p1@ELF1!1.13!80.08!ELF1;;chr20:50159198..50159299,-!p1@NFATC2!1.11!17.47!NFATC2;;chr7:50344289..50344323,+!p1@IKZF1!1.11!11.89!IKZF1;;chr2:60781201..60781258,-!p3@BCL11A!1.10!11.71!BCL11A;;chrY:21906594..21906622,-!p1@KDM5D!1.10!11.52!KDM5D;;chr6:135502501..135502546,+!p1@MYB!1.09!13.56!MYB;;chr2:214016254..214016282,-!p7@IKZF2!1.09!11.33!IKZF2;;chr2:231090344..231090361,-!p3@SP110!1.09!11.33!SP110;;chr15:57511589..57511608,+!p4@TCF12!1.08!11.15!TCF12;;chr18:53089538..53089578,-!p14@TCF4!1.08!11.15!TCF4;;chr1:158975744..158975769,+!p10@IFI16!1.08!11.15!IFI16;;chr2:214013461..214013517,-!p6@IKZF2!1.08!10.96!IKZF2;;chr9:37034469..37034474,-!p1@PAX5!1.08!10.96!PAX5;;chr7:64126503..64126528,+!p1@ZNF107!1.07!76.55!ZNF107;;chr6:34204973..34204990,+!p4@HMGA1!1.06!141.77!HMGA1;;chr7:115799916..115799932,-!p6@TFEC!1.06!10.59!TFEC;;chr19:45579725..45579743,-!p1@ZNF296!1.04!45.15!ZNF296;;chr5:124084493..124084524,-!p2@ZNF608!1.04!22.48!ZNF608;;chr17:42295777..42295816,-!p7@UBTF!1.04!12.08!UBTF;;chr19:36204309..36204335,+!p1@ZBTB32!1.04!10.03!ZBTB32;;chr9:37034186..37034216,-!p2@PAX5!1.04!10.03!PAX5;;chr17:38020557..38020572,-!p4@IKZF3!1.04!9.85!IKZF3;;chr18:52989001..52989030,-!p10@TCF4!1.03!10.78!TCF4;;chr18:53089521..53089533,-!p22@TCF4!1.03!9.66!TCF4;;chr18:53255415..53255491,-!p1@TCF4!1.02!80.82!TCF4;;chr12:54447599..54447630,+!p3@HOXC4!1.02!11.71!HOXC4;;chr1:158979686..158979745,+!p1@IFI16!1.01!309.73!IFI16;;chr5:88178983..88179012,-!p1@MEF2C!1.01!72.65!MEF2C;;chr18:53089453..53089482,-!p11@TCF4!1.01!9.29!TCF4;;chr17:37934204..37934241,-!p3@IKZF3!1.00!8.92!IKZF3;;chr8:86099884..86099918,+!p4@E2F5!1.00!8.92!E2F5;;chr7:64838786..64838809,+!p2@ZNF92!0.98!49.42!ZNF92;;chr18:53257027..53257052,-!p3@TCF4!0.98!35.30!TCF4;;chr2:100758991..100759009,-!p3@AFF3!0.98!8.55!AFF3;;chr19:1652555..1652568,-!p2@TCF3!0.97!34.93!TCF3;;chr11:19262461..19262476,-!p5@E2F8!0.97!8.36!E2F8;;chr19:42627037..42627084,-!p3@POU2F2!0.97!8.36!POU2F2;;chr9:117150254..117150271,-!p1@AKNA!0.96!23.04!AKNA;;chr4:109089901..109089930,-!p3@LEF1!0.96!8.18!LEF1;;chr21:36421535..36421610,-!p2@RUNX1!0.95!29.17!RUNX1;;chr14:75988831..75988847,+!p2@BATF!0.95!7.99!BATF;;chr7:28610099..28610113,+!p5@CREB5!0.95!7.99!CREB5;;chr9:37034258..37034270,-!p3@PAX5!0.95!7.99!PAX5;;chr1:226595726..226595737,-!p2@PARP1!0.94!19.14!PARP1;;chr5:158526917..158526932,-!p1@EBF1!0.92!18.77!EBF1;;chr13:41593493..41593506,-!p8@ELF1!0.92!7.25!ELF1;;chr3:71179699..71179744,-!p2@FOXP1!0.91!56.30!FOXP1;;chr12:26277956..26277980,-!p1@BHLHE41!0.91!26.57!BHLHE41;;chr4:4291837..4291859,-!p2@LYAR!0.91!24.15!LYAR;;chr7:128577972..128578047,+!p1@IRF5!0.91!11.52!IRF5;;chr18:53257068..53257086,-!p12@TCF4!0.91!9.85!TCF4;;chr2:239148671..239148686,-!p1@HES6!0.89!26.01!HES6;;chr10:135122868..135122893,+!p3@ZNF511!0.89!6.69!ZNF511;;chr1:25256756..25256774,-!p1@RUNX3!0.88!12.82!RUNX3;;chr18:52989565..52989623,-!p9@TCF4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| ||
|ffid_belonging_in_development=CL:0000134,CL:0000051 | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
| Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520lymphoblastic%2520leukemia%2520%2528B-ALL%2529%2520cell%2520line%253aBALL-1.CNhs11251.10455-106G5.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520lymphoblastic%2520leukemia%2520%2528B-ALL%2529%2520cell%2520line%253aBALL-1.CNhs11251.10455-106G5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520lymphoblastic%2520leukemia%2520%2528B-ALL%2529%2520cell%2520line%253aBALL-1.CNhs11251.10455-106G5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520lymphoblastic%2520leukemia%2520%2528B-ALL%2529%2520cell%2520line%253aBALL-1.CNhs11251.10455-106G5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520lymphoblastic%2520leukemia%2520%2528B-ALL%2529%2520cell%2520line%253aBALL-1.CNhs11251.10455-106G5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10455-106G5 | |id=FF:10455-106G5 | ||
|is_a=DOID:12603;;EFO:0002091;;FF: | |is_a=DOID:12603;;EFO:0002091;;FF:0000210;;FF:0102144 | ||
|is_obsolete= | |||
|library_id=CNhs11251 | |||
|library_id_phase_based=2:CNhs11251 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10455 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10455 | |||
|name=acute lymphoblastic leukemia (B-ALL) cell line:BALL-1 | |name=acute lymphoblastic leukemia (B-ALL) cell line:BALL-1 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs11251,LSID757,release008,COMPLETED | |profile_hcage=CNhs11251,LSID757,release008,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.125017771777055,0,-0.0849593056075685,-0.282403560576942,0,0,0,0,0,0,0,0,0,0.241350381383577,0,0,0,-0.153323010348428,0,0,0,0,0.77935732743172,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0,0,-0.0164306324745828,0,0,0,0,0,0,0,0,0.0127912833293734,0,0,0,0,0,-0.0069782990331447,0,-0.0969923612426051,0,0,-0.0233310183286815,0,0,0,0,0,0,0,0,0.0740126088844155,0,0.50915386000188,0,0,0,0,0,0,0.0685868371617208,0,0,0,0,0,0,-0.0863365012627497,0,0,0,-0.0611723899898289,0.146567724351549,0,0,0.0370063044422078,0.0740126088844155,-0.0980353512377064,-0.101470896358687,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.285813458025856,0,0,0,-0.11059099517702,-0.197919821264422,0,0,0,0,0,0 | |||
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| |||
|rna_box=106 | |rna_box=106 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 57: | Line 78: | ||
|rna_weight_ug=48.1707 | |rna_weight_ug=48.1707 | ||
|sample_age=unknown | |sample_age=unknown | ||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB0256 | |sample_cell_catalog=RCB0256 | ||
|sample_cell_line=BALL-1 | |sample_cell_line=BALL-1 | ||
| Line 69: | Line 91: | ||
|sample_ethnicity=unknown | |sample_ethnicity=unknown | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.7751787202712e-266!GO:0043227;membrane-bound organelle;3.16990798933525e-239!GO:0043231;intracellular membrane-bound organelle;6.27176231452542e-239!GO:0043226;organelle;4.91997959322014e-226!GO:0043229;intracellular organelle;2.23295725054195e-225!GO:0044422;organelle part;2.0478823537792e-171!GO:0044446;intracellular organelle part;1.27428704806516e-169!GO:0005737;cytoplasm;2.23275899434459e-164!GO:0032991;macromolecular complex;1.271152841927e-134!GO:0005634;nucleus;1.50517164518333e-122!GO:0044444;cytoplasmic part;6.42109688811705e-118!GO:0044237;cellular metabolic process;6.49271384118646e-112!GO:0044428;nuclear part;4.06253577189319e-109!GO:0044238;primary metabolic process;2.3115745415832e-107!GO:0030529;ribonucleoprotein complex;3.99503185396187e-107!GO:0043170;macromolecule metabolic process;7.30457981729736e-102!GO:0003723;RNA binding;1.91005765285872e-97!GO:0043233;organelle lumen;2.16803451077881e-97!GO:0031974;membrane-enclosed lumen;2.16803451077881e-97!GO:0005739;mitochondrion;1.60751516130352e-79!GO:0006396;RNA processing;2.2655275626789e-72!GO:0043234;protein complex;4.39852234170289e-70!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.04933097517127e-67!GO:0031981;nuclear lumen;1.62812044265138e-65!GO:0043283;biopolymer metabolic process;3.439345132585e-64!GO:0006412;translation;4.7602565983151e-64!GO:0005515;protein binding;5.74435574122877e-63!GO:0010467;gene expression;1.65411806877471e-62!GO:0005840;ribosome;6.62140144452522e-60!GO:0044429;mitochondrial part;1.06888750213043e-55!GO:0016071;mRNA metabolic process;2.75660307825948e-54!GO:0006259;DNA metabolic process;6.42067517021219e-53!GO:0003735;structural constituent of ribosome;3.94641814454505e-52!GO:0031967;organelle envelope;1.31505879146798e-50!GO:0031975;envelope;3.30289561702063e-50!GO:0008380;RNA splicing;8.12602176744549e-49!GO:0006397;mRNA processing;1.01293611652581e-47!GO:0031090;organelle membrane;1.27638866307799e-47!GO:0003676;nucleic acid binding;2.41741971742401e-46!GO:0009058;biosynthetic process;4.11389154349292e-46!GO:0044249;cellular biosynthetic process;4.56162214764547e-46!GO:0033279;ribosomal subunit;5.47257068113215e-46!GO:0009059;macromolecule biosynthetic process;5.57606705722979e-46!GO:0019538;protein metabolic process;8.51207361052224e-46!GO:0005654;nucleoplasm;7.38813589371749e-43!GO:0033036;macromolecule localization;1.83515790697334e-42!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.04088720999647e-41!GO:0044267;cellular protein metabolic process;2.15145153967673e-41!GO:0015031;protein transport;4.28690008336794e-41!GO:0044260;cellular macromolecule metabolic process;6.47739902900781e-41!GO:0046907;intracellular transport;3.34841566956858e-38!GO:0006996;organelle organization and biogenesis;5.44981103819347e-38!GO:0045184;establishment of protein localization;7.2510160429663e-38!GO:0008104;protein localization;8.18157011100086e-38!GO:0016043;cellular component organization and biogenesis;1.00412795098959e-37!GO:0005829;cytosol;7.58499666412128e-37!GO:0006974;response to DNA damage stimulus;4.53309997848411e-36!GO:0005681;spliceosome;5.78527531683538e-36!GO:0007049;cell cycle;7.26413680483565e-36!GO:0065003;macromolecular complex assembly;1.00122016748313e-35!GO:0043228;non-membrane-bound organelle;1.54349485770811e-35!GO:0043232;intracellular non-membrane-bound organelle;1.54349485770811e-35!GO:0005740;mitochondrial envelope;2.45100798121468e-34!GO:0019866;organelle inner membrane;1.44705109917603e-32!GO:0006886;intracellular protein transport;1.48077797077696e-32!GO:0044451;nucleoplasm part;3.24328648814006e-32!GO:0031966;mitochondrial membrane;7.24664546875139e-32!GO:0005694;chromosome;7.47469691910659e-32!GO:0006281;DNA repair;1.0225394627463e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.5744818848969e-31!GO:0000166;nucleotide binding;5.20194931733293e-31!GO:0022607;cellular component assembly;1.41553559809736e-30!GO:0005743;mitochondrial inner membrane;2.94839952821609e-30!GO:0016070;RNA metabolic process;8.41316466637317e-30!GO:0044445;cytosolic part;1.73113346295759e-29!GO:0000278;mitotic cell cycle;3.06772046195141e-29!GO:0022402;cell cycle process;1.70404885985448e-28!GO:0044427;chromosomal part;6.80037217914788e-27!GO:0022403;cell cycle phase;9.0440281868957e-27!GO:0051649;establishment of cellular localization;1.51015413301366e-26!GO:0051641;cellular localization;7.02948985856293e-26!GO:0000087;M phase of mitotic cell cycle;1.17794670073795e-25!GO:0031980;mitochondrial lumen;1.65160895064929e-25!GO:0005759;mitochondrial matrix;1.65160895064929e-25!GO:0007067;mitosis;4.58936075949683e-25!GO:0016462;pyrophosphatase activity;1.22846673571149e-24!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.28996053714361e-24!GO:0016817;hydrolase activity, acting on acid anhydrides;1.59894697826736e-24!GO:0009719;response to endogenous stimulus;1.65272810133167e-24!GO:0015935;small ribosomal subunit;2.23319234109855e-24!GO:0017111;nucleoside-triphosphatase activity;3.52908935585265e-24!GO:0005730;nucleolus;6.12691973598047e-24!GO:0044455;mitochondrial membrane part;9.44923690575195e-24!GO:0000279;M phase;1.25019394471144e-23!GO:0006119;oxidative phosphorylation;1.78215705332689e-23!GO:0022618;protein-RNA complex assembly;5.65878879133119e-23!GO:0015934;large ribosomal subunit;7.46460724717079e-23!GO:0051301;cell division;3.18922179318111e-22!GO:0051276;chromosome organization and biogenesis;4.98134666041346e-22!GO:0032553;ribonucleotide binding;5.05973808366339e-22!GO:0032555;purine ribonucleotide binding;5.05973808366339e-22!GO:0006260;DNA replication;9.15718393436545e-22!GO:0017076;purine nucleotide binding;1.62117912577065e-21!GO:0005524;ATP binding;3.400214207238e-21!GO:0016874;ligase activity;5.71529053220244e-21!GO:0032559;adenyl ribonucleotide binding;1.18694345643986e-20!GO:0044265;cellular macromolecule catabolic process;1.99908034671186e-20!GO:0006457;protein folding;2.52267338729974e-20!GO:0008135;translation factor activity, nucleic acid binding;3.95154363793687e-20!GO:0016887;ATPase activity;5.71588087628188e-20!GO:0030554;adenyl nucleotide binding;5.76752653971761e-20!GO:0042623;ATPase activity, coupled;9.06438502779561e-20!GO:0005761;mitochondrial ribosome;3.89756142381293e-19!GO:0000313;organellar ribosome;3.89756142381293e-19!GO:0042254;ribosome biogenesis and assembly;4.2264957935416e-19!GO:0006512;ubiquitin cycle;4.48812926523943e-19!GO:0005746;mitochondrial respiratory chain;1.27143252549915e-18!GO:0012505;endomembrane system;3.03740037090661e-18!GO:0006605;protein targeting;5.48644327980296e-18!GO:0016604;nuclear body;7.54115727876236e-18!GO:0000398;nuclear mRNA splicing, via spliceosome;1.16706994205654e-17!GO:0000375;RNA splicing, via transesterification reactions;1.16706994205654e-17!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.16706994205654e-17!GO:0000502;proteasome complex (sensu Eukaryota);1.48692251702195e-17!GO:0008134;transcription factor binding;1.8101907438685e-17!GO:0005635;nuclear envelope;2.58225097782805e-17!GO:0043285;biopolymer catabolic process;5.22955136165328e-17!GO:0009057;macromolecule catabolic process;6.63693989570782e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);8.38268597760454e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;8.80253274135751e-17!GO:0050136;NADH dehydrogenase (quinone) activity;1.03855890340413e-16!GO:0003954;NADH dehydrogenase activity;1.03855890340413e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.03855890340413e-16!GO:0019941;modification-dependent protein catabolic process;1.55158558877481e-16!GO:0043632;modification-dependent macromolecule catabolic process;1.55158558877481e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;1.93660031178992e-16!GO:0006511;ubiquitin-dependent protein catabolic process;2.20871809541815e-16!GO:0044248;cellular catabolic process;3.45284355989939e-16!GO:0044257;cellular protein catabolic process;5.23199453454114e-16!GO:0044453;nuclear membrane part;6.07599692357432e-16!GO:0031965;nuclear membrane;7.27919628113907e-16!GO:0006399;tRNA metabolic process;1.05331522823378e-15!GO:0004386;helicase activity;1.29518232943827e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.6721569664699e-15!GO:0006325;establishment and/or maintenance of chromatin architecture;2.51125104485405e-15!GO:0006913;nucleocytoplasmic transport;3.6430559595752e-15!GO:0006323;DNA packaging;9.30938367165097e-15!GO:0042775;organelle ATP synthesis coupled electron transport;1.03185364140314e-14!GO:0042773;ATP synthesis coupled electron transport;1.03185364140314e-14!GO:0051169;nuclear transport;1.05804110537479e-14!GO:0003743;translation initiation factor activity;1.47304426007876e-14!GO:0005643;nuclear pore;1.52140999847806e-14!GO:0006413;translational initiation;1.6757955940626e-14!GO:0030964;NADH dehydrogenase complex (quinone);1.74568179086484e-14!GO:0045271;respiratory chain complex I;1.74568179086484e-14!GO:0005747;mitochondrial respiratory chain complex I;1.74568179086484e-14!GO:0051186;cofactor metabolic process;1.92604252858632e-14!GO:0012501;programmed cell death;2.17858552141939e-14!GO:0006915;apoptosis;2.42689025339705e-14!GO:0048770;pigment granule;2.52167483724285e-14!GO:0042470;melanosome;2.52167483724285e-14!GO:0006403;RNA localization;2.62400104405489e-14!GO:0050657;nucleic acid transport;2.80772325250706e-14!GO:0051236;establishment of RNA localization;2.80772325250706e-14!GO:0050658;RNA transport;2.80772325250706e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.96386348721874e-14!GO:0051082;unfolded protein binding;6.44058568748666e-14!GO:0016607;nuclear speck;6.52013210440552e-14!GO:0065002;intracellular protein transport across a membrane;8.51842723008938e-14!GO:0008026;ATP-dependent helicase activity;1.57562857120359e-13!GO:0000775;chromosome, pericentric region;2.3465453454379e-13!GO:0006364;rRNA processing;7.43738483104207e-13!GO:0008219;cell death;8.36612129778611e-13!GO:0016265;death;8.36612129778611e-13!GO:0006446;regulation of translational initiation;9.58425941635048e-13!GO:0016072;rRNA metabolic process;1.21517602021244e-12!GO:0016779;nucleotidyltransferase activity;1.4478610938576e-12!GO:0043412;biopolymer modification;1.78343571311322e-12!GO:0046930;pore complex;1.89597131793733e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.57854796751919e-12!GO:0044432;endoplasmic reticulum part;2.61723659591547e-12!GO:0051028;mRNA transport;3.62365132908806e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.81579530389343e-12!GO:0030163;protein catabolic process;3.85244184172439e-12!GO:0000785;chromatin;5.94478582921145e-12!GO:0016568;chromatin modification;6.87312006264176e-12!GO:0051726;regulation of cell cycle;1.02664367945667e-11!GO:0005783;endoplasmic reticulum;1.09963744574632e-11!GO:0009259;ribonucleotide metabolic process;1.19830242772622e-11!GO:0006732;coenzyme metabolic process;1.47145818491295e-11!GO:0000074;regulation of progression through cell cycle;1.59772187813826e-11!GO:0008565;protein transporter activity;2.11177175415458e-11!GO:0006163;purine nucleotide metabolic process;2.42853040358873e-11!GO:0043566;structure-specific DNA binding;3.60350100262929e-11!GO:0006261;DNA-dependent DNA replication;6.5573356125057e-11!GO:0006164;purine nucleotide biosynthetic process;8.08539843019186e-11!GO:0003712;transcription cofactor activity;1.01270073317035e-10!GO:0017038;protein import;1.25284744581498e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.4201297461282e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.55865744654075e-10!GO:0009260;ribonucleotide biosynthetic process;1.6091570985329e-10!GO:0003697;single-stranded DNA binding;1.90821353911823e-10!GO:0006333;chromatin assembly or disassembly;2.02163914919895e-10!GO:0005789;endoplasmic reticulum membrane;2.45350592313703e-10!GO:0048193;Golgi vesicle transport;3.16630108310567e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;3.24955481079018e-10!GO:0004812;aminoacyl-tRNA ligase activity;3.24955481079018e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;3.24955481079018e-10!GO:0009150;purine ribonucleotide metabolic process;4.5186127288232e-10!GO:0043038;amino acid activation;6.01010441430573e-10!GO:0006418;tRNA aminoacylation for protein translation;6.01010441430573e-10!GO:0043039;tRNA aminoacylation;6.01010441430573e-10!GO:0006464;protein modification process;6.21516767604148e-10!GO:0016787;hydrolase activity;6.83506422664925e-10!GO:0030532;small nuclear ribonucleoprotein complex;7.65894961363468e-10!GO:0006461;protein complex assembly;1.00368975597507e-09!GO:0008639;small protein conjugating enzyme activity;1.10740694413075e-09!GO:0009152;purine ribonucleotide biosynthetic process;1.5167157597061e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.52595377712682e-09!GO:0007005;mitochondrion organization and biogenesis;1.68442283243876e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.73425186016856e-09!GO:0004842;ubiquitin-protein ligase activity;2.48126994952123e-09!GO:0009055;electron carrier activity;2.60028771602024e-09!GO:0065004;protein-DNA complex assembly;3.96816933669476e-09!GO:0043687;post-translational protein modification;4.37652510337325e-09!GO:0019829;cation-transporting ATPase activity;6.18558951003332e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;7.41800887910928e-09!GO:0042981;regulation of apoptosis;7.42690127308247e-09!GO:0015078;hydrogen ion transmembrane transporter activity;8.111543827647e-09!GO:0019787;small conjugating protein ligase activity;8.39109712188267e-09!GO:0009056;catabolic process;8.84227070206485e-09!GO:0005819;spindle;9.758668733806e-09!GO:0043067;regulation of programmed cell death;1.01786352365126e-08!GO:0016740;transferase activity;1.06475005551003e-08!GO:0009060;aerobic respiration;1.48085639524901e-08!GO:0009199;ribonucleoside triphosphate metabolic process;1.64501970438442e-08!GO:0009141;nucleoside triphosphate metabolic process;1.7043921333843e-08!GO:0051188;cofactor biosynthetic process;1.92122556875919e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.94733214380158e-08!GO:0000075;cell cycle checkpoint;2.09589986720236e-08!GO:0003899;DNA-directed RNA polymerase activity;2.19568822503957e-08!GO:0009142;nucleoside triphosphate biosynthetic process;2.54083378593354e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.54083378593354e-08!GO:0015986;ATP synthesis coupled proton transport;2.99455886821936e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.99455886821936e-08!GO:0005839;proteasome core complex (sensu Eukaryota);3.4645089919495e-08!GO:0006310;DNA recombination;3.61801196921709e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.84934241857295e-08!GO:0009144;purine nucleoside triphosphate metabolic process;3.84934241857295e-08!GO:0000245;spliceosome assembly;4.17205889325226e-08!GO:0015630;microtubule cytoskeleton;4.40419790199227e-08!GO:0007051;spindle organization and biogenesis;4.51972097334704e-08!GO:0005657;replication fork;4.78191216195308e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;6.27788629438476e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;6.27788629438476e-08!GO:0008094;DNA-dependent ATPase activity;7.13291565458526e-08!GO:0045333;cellular respiration;8.62448734537128e-08!GO:0016881;acid-amino acid ligase activity;9.50965816924763e-08!GO:0016192;vesicle-mediated transport;1.25748732970647e-07!GO:0006099;tricarboxylic acid cycle;1.25748732970647e-07!GO:0046356;acetyl-CoA catabolic process;1.25748732970647e-07!GO:0051246;regulation of protein metabolic process;1.29039768735846e-07!GO:0050794;regulation of cellular process;1.37263805329735e-07!GO:0046034;ATP metabolic process;1.47005043922241e-07!GO:0004298;threonine endopeptidase activity;1.73836582631332e-07!GO:0006754;ATP biosynthetic process;1.79134154648603e-07!GO:0006753;nucleoside phosphate metabolic process;1.79134154648603e-07!GO:0006084;acetyl-CoA metabolic process;1.84647323353638e-07!GO:0051170;nuclear import;1.85929805069223e-07!GO:0004518;nuclease activity;1.93367822451349e-07!GO:0032446;protein modification by small protein conjugation;2.10107691581614e-07!GO:0051325;interphase;2.3442011683927e-07!GO:0006302;double-strand break repair;2.41729911966405e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.42950179121368e-07!GO:0005667;transcription factor complex;2.49257399697758e-07!GO:0045259;proton-transporting ATP synthase complex;2.60708085952502e-07!GO:0051168;nuclear export;2.63357949428472e-07!GO:0016563;transcription activator activity;2.90816511060772e-07!GO:0006366;transcription from RNA polymerase II promoter;2.95797443147226e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.97274261443095e-07!GO:0009117;nucleotide metabolic process;3.28354964212679e-07!GO:0051329;interphase of mitotic cell cycle;3.45255213964609e-07!GO:0019222;regulation of metabolic process;3.51929609643083e-07!GO:0007059;chromosome segregation;3.60175321048968e-07!GO:0005813;centrosome;4.08487181510828e-07!GO:0016567;protein ubiquitination;4.56299080929919e-07!GO:0006752;group transfer coenzyme metabolic process;5.07440600738782e-07!GO:0008033;tRNA processing;5.96424171720728e-07!GO:0006606;protein import into nucleus;6.24274208322391e-07!GO:0005815;microtubule organizing center;6.3203287986584e-07!GO:0006888;ER to Golgi vesicle-mediated transport;7.38009961422573e-07!GO:0048475;coated membrane;8.77876498379144e-07!GO:0030117;membrane coat;8.77876498379144e-07!GO:0009108;coenzyme biosynthetic process;8.88615161173147e-07!GO:0005762;mitochondrial large ribosomal subunit;9.04878541783024e-07!GO:0000315;organellar large ribosomal subunit;9.04878541783024e-07!GO:0003684;damaged DNA binding;9.32870362450506e-07!GO:0003724;RNA helicase activity;9.61049627771136e-07!GO:0003713;transcription coactivator activity;9.62169131124203e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;9.87670944833189e-07!GO:0009109;coenzyme catabolic process;1.06799101396325e-06!GO:0030120;vesicle coat;1.30137382875456e-06!GO:0030662;coated vesicle membrane;1.30137382875456e-06!GO:0000776;kinetochore;1.33901994477908e-06!GO:0019899;enzyme binding;1.53015220586297e-06!GO:0005794;Golgi apparatus;1.66572367321159e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.8493212244987e-06!GO:0003690;double-stranded DNA binding;1.89453819167154e-06!GO:0005793;ER-Golgi intermediate compartment;2.08085395726233e-06!GO:0006793;phosphorus metabolic process;2.20897790797258e-06!GO:0006796;phosphate metabolic process;2.20897790797258e-06!GO:0044452;nucleolar part;2.36504117040918e-06!GO:0000151;ubiquitin ligase complex;2.4284941364573e-06!GO:0016741;transferase activity, transferring one-carbon groups;2.74999090852709e-06!GO:0008168;methyltransferase activity;3.2716244575854e-06!GO:0000314;organellar small ribosomal subunit;3.28302671479466e-06!GO:0005763;mitochondrial small ribosomal subunit;3.28302671479466e-06!GO:0006401;RNA catabolic process;3.33945901031526e-06!GO:0007088;regulation of mitosis;3.51982405393598e-06!GO:0043623;cellular protein complex assembly;3.62799393943175e-06!GO:0051187;cofactor catabolic process;4.25661326212314e-06!GO:0016363;nuclear matrix;4.77555644502477e-06!GO:0005768;endosome;4.90802626992343e-06!GO:0006613;cotranslational protein targeting to membrane;5.15879368023537e-06!GO:0016310;phosphorylation;6.12425810675906e-06!GO:0006839;mitochondrial transport;6.45623739032042e-06!GO:0051052;regulation of DNA metabolic process;7.51980032133085e-06!GO:0003682;chromatin binding;8.22935523604035e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;8.99546341375638e-06!GO:0015399;primary active transmembrane transporter activity;8.99546341375638e-06!GO:0030880;RNA polymerase complex;8.99546341375638e-06!GO:0004527;exonuclease activity;9.44218353742843e-06!GO:0006612;protein targeting to membrane;1.05938735834758e-05!GO:0006334;nucleosome assembly;1.12211488659591e-05!GO:0031497;chromatin assembly;1.13894415158202e-05!GO:0003678;DNA helicase activity;1.26063512282793e-05!GO:0006626;protein targeting to mitochondrion;1.64997458570849e-05!GO:0031323;regulation of cellular metabolic process;1.78871022946104e-05!GO:0006414;translational elongation;1.90129065330178e-05!GO:0006383;transcription from RNA polymerase III promoter;2.02229897401833e-05!GO:0055029;nuclear DNA-directed RNA polymerase complex;2.46615330095712e-05!GO:0000428;DNA-directed RNA polymerase complex;2.46615330095712e-05!GO:0043021;ribonucleoprotein binding;2.70043478231461e-05!GO:0043681;protein import into mitochondrion;2.97168517002316e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;2.9923248654525e-05!GO:0065009;regulation of a molecular function;3.65123927606593e-05!GO:0006402;mRNA catabolic process;3.95972266735863e-05!GO:0007093;mitotic cell cycle checkpoint;4.1780426535073e-05!GO:0031072;heat shock protein binding;4.45277886696034e-05!GO:0005770;late endosome;4.83454114589214e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;4.88492723881434e-05!GO:0007006;mitochondrial membrane organization and biogenesis;5.49138254162427e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.7581682102326e-05!GO:0009165;nucleotide biosynthetic process;5.81914625417191e-05!GO:0043069;negative regulation of programmed cell death;6.09888885776946e-05!GO:0008186;RNA-dependent ATPase activity;6.21145683407338e-05!GO:0006350;transcription;6.60811847276279e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;7.59300056879642e-05!GO:0043066;negative regulation of apoptosis;7.96244433941967e-05!GO:0016853;isomerase activity;8.56142003546409e-05!GO:0031324;negative regulation of cellular metabolic process;9.23915116945003e-05!GO:0006352;transcription initiation;9.60703864875401e-05!GO:0000228;nuclear chromosome;9.79051333061645e-05!GO:0006916;anti-apoptosis;0.000103821365129162!GO:0003729;mRNA binding;0.000110626420732657!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000131510331747301!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000134953380264061!GO:0016564;transcription repressor activity;0.000143830678985514!GO:0008654;phospholipid biosynthetic process;0.000149090391312536!GO:0043492;ATPase activity, coupled to movement of substances;0.000163346966257999!GO:0006417;regulation of translation;0.000163963949402023!GO:0043065;positive regulation of apoptosis;0.000168465489796459!GO:0006091;generation of precursor metabolites and energy;0.000170325858449704!GO:0004004;ATP-dependent RNA helicase activity;0.000196891063577849!GO:0016491;oxidoreductase activity;0.000197194727606617!GO:0051427;hormone receptor binding;0.0002013632471861!GO:0032508;DNA duplex unwinding;0.000203197579396205!GO:0032392;DNA geometric change;0.000203197579396205!GO:0007052;mitotic spindle organization and biogenesis;0.000208437607026649!GO:0043068;positive regulation of programmed cell death;0.000223944720218559!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000237414887220717!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000243292489085208!GO:0006284;base-excision repair;0.000244453223497265!GO:0000059;protein import into nucleus, docking;0.000247523064516017!GO:0006405;RNA export from nucleus;0.000265336315889531!GO:0000049;tRNA binding;0.000266662011691856!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000269283513148291!GO:0016251;general RNA polymerase II transcription factor activity;0.000277211470256104!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000287511251345642!GO:0005885;Arp2/3 protein complex;0.000305846575437917!GO:0050789;regulation of biological process;0.000307920623932872!GO:0005798;Golgi-associated vesicle;0.000307920623932872!GO:0006818;hydrogen transport;0.000319159862353687!GO:0006950;response to stress;0.000366200196161919!GO:0030384;phosphoinositide metabolic process;0.000375851156994183!GO:0015992;proton transport;0.000376555156875031!GO:0008632;apoptotic program;0.000376952424529361!GO:0035257;nuclear hormone receptor binding;0.000397929329485601!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000401454509887978!GO:0016859;cis-trans isomerase activity;0.000424226643459004!GO:0000070;mitotic sister chromatid segregation;0.000447184873557222!GO:0005876;spindle microtubule;0.000475530288612343!GO:0044440;endosomal part;0.000479440947038455!GO:0010008;endosome membrane;0.000479440947038455!GO:0006268;DNA unwinding during replication;0.000490596329191634!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000506771546132814!GO:0003746;translation elongation factor activity;0.000513469258900075!GO:0016126;sterol biosynthetic process;0.000520610023786556!GO:0031968;organelle outer membrane;0.000529620993381588!GO:0045454;cell redox homeostasis;0.000529620993381588!GO:0005684;U2-dependent spliceosome;0.000539136599365695!GO:0010468;regulation of gene expression;0.000543500501316048!GO:0000819;sister chromatid segregation;0.000547245663275234!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000579922221563499!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.000582211772989452!GO:0006917;induction of apoptosis;0.000589498543806638!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.000625904106326741!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000635400199947209!GO:0032200;telomere organization and biogenesis;0.000640718713512389!GO:0000723;telomere maintenance;0.000640718713512389!GO:0042393;histone binding;0.000659124917255292!GO:0005741;mitochondrial outer membrane;0.000661299513836437!GO:0019867;outer membrane;0.000665585217134947!GO:0046489;phosphoinositide biosynthetic process;0.000683149981523754!GO:0015631;tubulin binding;0.000711474922074099!GO:0045786;negative regulation of progression through cell cycle;0.000740710938173942!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000741661711429416!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000741661711429416!GO:0046483;heterocycle metabolic process;0.000764973339815679!GO:0051789;response to protein stimulus;0.000790003256743608!GO:0006986;response to unfolded protein;0.000790003256743608!GO:0012502;induction of programmed cell death;0.000797133339037598!GO:0046474;glycerophospholipid biosynthetic process;0.000873493333267904!GO:0000725;recombinational repair;0.000904332632325605!GO:0000724;double-strand break repair via homologous recombination;0.000904332632325605!GO:0022415;viral reproductive process;0.000920778465110082!GO:0005525;GTP binding;0.000920793054243524!GO:0016481;negative regulation of transcription;0.000927213269777395!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000927213269777395!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000927213269777395!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000927213269777395!GO:0022890;inorganic cation transmembrane transporter activity;0.000929052492907905!GO:0044431;Golgi apparatus part;0.000997716685005563!GO:0051920;peroxiredoxin activity;0.000997716685005563!GO:0048523;negative regulation of cellular process;0.000997716685005563!GO:0005773;vacuole;0.000998317348282295!GO:0005758;mitochondrial intermembrane space;0.00100549258326903!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00100551237210926!GO:0031326;regulation of cellular biosynthetic process;0.0010534552356071!GO:0048500;signal recognition particle;0.00109914736470307!GO:0043596;nuclear replication fork;0.00110752690475648!GO:0006289;nucleotide-excision repair;0.00116987378325299!GO:0000082;G1/S transition of mitotic cell cycle;0.00117532326310004!GO:0005048;signal sequence binding;0.00117900655644995!GO:0003924;GTPase activity;0.00118137066180939!GO:0006650;glycerophospholipid metabolic process;0.00119695339104057!GO:0006338;chromatin remodeling;0.00119819945392993!GO:0006275;regulation of DNA replication;0.00124790814952492!GO:0003887;DNA-directed DNA polymerase activity;0.00125379709146564!GO:0051252;regulation of RNA metabolic process;0.00126011403081694!GO:0009892;negative regulation of metabolic process;0.00126011403081694!GO:0004674;protein serine/threonine kinase activity;0.00126249014808686!GO:0009112;nucleobase metabolic process;0.00131319378862373!GO:0009451;RNA modification;0.00132959413579793!GO:0000323;lytic vacuole;0.00138996658022212!GO:0005764;lysosome;0.00138996658022212!GO:0008312;7S RNA binding;0.00139748739272792!GO:0031124;mRNA 3'-end processing;0.00141186514652233!GO:0003714;transcription corepressor activity;0.0014349542535133!GO:0003711;transcription elongation regulator activity;0.00144477327209791!GO:0006595;polyamine metabolic process;0.00147729644100174!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00149902292648913!GO:0006611;protein export from nucleus;0.00151356592993518!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00153836996146287!GO:0003677;DNA binding;0.00154715645883244!GO:0006695;cholesterol biosynthetic process;0.00169336104909778!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00171934873925347!GO:0006891;intra-Golgi vesicle-mediated transport;0.00173982634278486!GO:0007017;microtubule-based process;0.00173982634278486!GO:0030658;transport vesicle membrane;0.00176450988659341!GO:0047485;protein N-terminus binding;0.00177281110746269!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00182267878978522!GO:0051087;chaperone binding;0.00182539538303152!GO:0000922;spindle pole;0.00182938036436284!GO:0019843;rRNA binding;0.00182992917346971!GO:0048471;perinuclear region of cytoplasm;0.00183039073780966!GO:0006270;DNA replication initiation;0.00192383916494537!GO:0008022;protein C-terminus binding;0.00196068540119697!GO:0016197;endosome transport;0.00201534965669913!GO:0031570;DNA integrity checkpoint;0.00201910894739085!GO:0006144;purine base metabolic process;0.0020660527365731!GO:0008408;3'-5' exonuclease activity;0.002080129168343!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00208582681838612!GO:0031970;organelle envelope lumen;0.00215286922075289!GO:0032259;methylation;0.00216781383077235!GO:0030663;COPI coated vesicle membrane;0.00221312412732117!GO:0030126;COPI vesicle coat;0.00221312412732117!GO:0051540;metal cluster binding;0.00240651475750311!GO:0051536;iron-sulfur cluster binding;0.00240651475750311!GO:0000781;chromosome, telomeric region;0.0024461865464215!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00247406153465461!GO:0045047;protein targeting to ER;0.00247406153465461!GO:0005637;nuclear inner membrane;0.00250652429922708!GO:0043284;biopolymer biosynthetic process;0.00257954723349024!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00262907808655823!GO:0015980;energy derivation by oxidation of organic compounds;0.00272666584283257!GO:0004003;ATP-dependent DNA helicase activity;0.00272666584283257!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00273528841952811!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00283732322607496!GO:0008139;nuclear localization sequence binding;0.00295881298665478!GO:0051053;negative regulation of DNA metabolic process;0.00299542747141694!GO:0031123;RNA 3'-end processing;0.00310349754686076!GO:0031902;late endosome membrane;0.00318412934165003!GO:0016272;prefoldin complex;0.00325308816792281!GO:0051539;4 iron, 4 sulfur cluster binding;0.00328721767109726!GO:0051098;regulation of binding;0.00358849323740502!GO:0004532;exoribonuclease activity;0.00366526091501068!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00366526091501068!GO:0009889;regulation of biosynthetic process;0.00370267360034933!GO:0000786;nucleosome;0.00371147657553278!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00392858109220551!GO:0000287;magnesium ion binding;0.00392858109220551!GO:0000792;heterochromatin;0.00396227272793946!GO:0006007;glucose catabolic process;0.00400214467048542!GO:0009615;response to virus;0.00401736321626805!GO:0004536;deoxyribonuclease activity;0.00407991561078941!GO:0008017;microtubule binding;0.00413477521410239!GO:0008180;signalosome;0.00414325029368623!GO:0019752;carboxylic acid metabolic process;0.00423544319047263!GO:0043414;biopolymer methylation;0.00425000026337162!GO:0046966;thyroid hormone receptor binding;0.00425000026337162!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00425000026337162!GO:0015002;heme-copper terminal oxidase activity;0.00425000026337162!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00425000026337162!GO:0004129;cytochrome-c oxidase activity;0.00425000026337162!GO:0030660;Golgi-associated vesicle membrane;0.00429221557626176!GO:0008276;protein methyltransferase activity;0.00434435898363671!GO:0006400;tRNA modification;0.00437738905244029!GO:0042770;DNA damage response, signal transduction;0.00437933802698061!GO:0000910;cytokinesis;0.00469846714951062!GO:0030118;clathrin coat;0.00471900588817808!GO:0006082;organic acid metabolic process;0.00476561359676197!GO:0043601;nuclear replisome;0.00485660057601681!GO:0030894;replisome;0.00485660057601681!GO:0016584;nucleosome positioning;0.00498429964181084!GO:0033116;ER-Golgi intermediate compartment membrane;0.00508213507549841!GO:0000726;non-recombinational repair;0.00524942930333392!GO:0050790;regulation of catalytic activity;0.00536672743009888!GO:0032561;guanyl ribonucleotide binding;0.00538225644115873!GO:0019001;guanyl nucleotide binding;0.00538225644115873!GO:0007243;protein kinase cascade;0.0054579762492615!GO:0006520;amino acid metabolic process;0.00557830913314663!GO:0005769;early endosome;0.00557830913314663!GO:0000339;RNA cap binding;0.00557830913314663!GO:0044454;nuclear chromosome part;0.00561553558538214!GO:0003725;double-stranded RNA binding;0.00564508071587218!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00587128308194043!GO:0000178;exosome (RNase complex);0.00599340634135269!GO:0009124;nucleoside monophosphate biosynthetic process;0.00604092466378592!GO:0009123;nucleoside monophosphate metabolic process;0.00604092466378592!GO:0000793;condensed chromosome;0.0062981067408176!GO:0008250;oligosaccharyl transferase complex;0.0063456794405375!GO:0042802;identical protein binding;0.00660617267015714!GO:0032774;RNA biosynthetic process;0.00685137768777479!GO:0043022;ribosome binding;0.00685137768777479!GO:0004540;ribonuclease activity;0.00694163436228622!GO:0008234;cysteine-type peptidase activity;0.00704542608578978!GO:0048519;negative regulation of biological process;0.00716122606994197!GO:0030119;AP-type membrane coat adaptor complex;0.00725412909289361!GO:0000077;DNA damage checkpoint;0.00742432038504317!GO:0048522;positive regulation of cellular process;0.00749837060007799!GO:0008610;lipid biosynthetic process;0.00752596770526244!GO:0043488;regulation of mRNA stability;0.00754242518216601!GO:0043487;regulation of RNA stability;0.00754242518216601!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00781764329382897!GO:0005663;DNA replication factor C complex;0.00788773604998498!GO:0005832;chaperonin-containing T-complex;0.00798788691795725!GO:0004576;oligosaccharyl transferase activity;0.00813243228297535!GO:0043189;H4/H2A histone acetyltransferase complex;0.00813243228297535!GO:0006351;transcription, DNA-dependent;0.00822477487544903!GO:0030137;COPI-coated vesicle;0.00824171898560199!GO:0000139;Golgi membrane;0.00824502475362237!GO:0005669;transcription factor TFIID complex;0.00824502475362237!GO:0007021;tubulin folding;0.00824504843972088!GO:0009303;rRNA transcription;0.008305695010258!GO:0019079;viral genome replication;0.00843270689542811!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00845463330586335!GO:0009116;nucleoside metabolic process;0.00845463330586335!GO:0006506;GPI anchor biosynthetic process;0.00866795896319449!GO:0035267;NuA4 histone acetyltransferase complex;0.00883509321869177!GO:0005874;microtubule;0.00908708841172542!GO:0046112;nucleobase biosynthetic process;0.00911490047645913!GO:0004519;endonuclease activity;0.00914134506021293!GO:0044450;microtubule organizing center part;0.00958315383247109!GO:0006220;pyrimidine nucleotide metabolic process;0.00959920431044282!GO:0030867;rough endoplasmic reticulum membrane;0.00969404364841131!GO:0031577;spindle checkpoint;0.00970145253383997!GO:0031252;leading edge;0.00984451811075119!GO:0006378;mRNA polyadenylation;0.00999814010436112!GO:0030433;ER-associated protein catabolic process;0.0100663416839903!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0100663416839903!GO:0030131;clathrin adaptor complex;0.0101091385068434!GO:0048487;beta-tubulin binding;0.0101159086787638!GO:0004520;endodeoxyribonuclease activity;0.0102103951966703!GO:0000152;nuclear ubiquitin ligase complex;0.0104490176135512!GO:0030134;ER to Golgi transport vesicle;0.0104490176135512!GO:0006505;GPI anchor metabolic process;0.0110852746256992!GO:0019058;viral infectious cycle;0.0110900542483227!GO:0006376;mRNA splice site selection;0.0114223137230025!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0114223137230025!GO:0016407;acetyltransferase activity;0.0116651309272749!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.0116651309272749!GO:0030133;transport vesicle;0.0117448332941075!GO:0032039;integrator complex;0.0117670266985965!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0124082998456316!GO:0046467;membrane lipid biosynthetic process;0.0125962437508492!GO:0016408;C-acyltransferase activity;0.0127090545349273!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0131239054937829!GO:0045039;protein import into mitochondrial inner membrane;0.0131239054937829!GO:0046365;monosaccharide catabolic process;0.0133112555748705!GO:0009161;ribonucleoside monophosphate metabolic process;0.0133871922838627!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0133871922838627!GO:0008156;negative regulation of DNA replication;0.013390432454689!GO:0005788;endoplasmic reticulum lumen;0.0134285606331585!GO:0000118;histone deacetylase complex;0.0134652421826792!GO:0045449;regulation of transcription;0.0144162265194411!GO:0031988;membrane-bound vesicle;0.0144542620039982!GO:0018196;peptidyl-asparagine modification;0.0145494252240176!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0145494252240176!GO:0006497;protein amino acid lipidation;0.0145722419917449!GO:0030127;COPII vesicle coat;0.0146135504554969!GO:0012507;ER to Golgi transport vesicle membrane;0.0146135504554969!GO:0042113;B cell activation;0.0148355247946651!GO:0050662;coenzyme binding;0.0150596386071771!GO:0006406;mRNA export from nucleus;0.0150644110409232!GO:0046164;alcohol catabolic process;0.0151887344382226!GO:0051320;S phase;0.0152897409121434!GO:0004523;ribonuclease H activity;0.0156945920109383!GO:0030508;thiol-disulfide exchange intermediate activity;0.0157711450685637!GO:0000123;histone acetyltransferase complex;0.0161025398638933!GO:0022411;cellular component disassembly;0.0161931706000787!GO:0007004;telomere maintenance via telomerase;0.0161931706000787!GO:0008538;proteasome activator activity;0.0162598361853519!GO:0000175;3'-5'-exoribonuclease activity;0.0162848897572265!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0164610803221879!GO:0006308;DNA catabolic process;0.0165154577753954!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0165522349068575!GO:0006596;polyamine biosynthetic process;0.0167005745965053!GO:0015036;disulfide oxidoreductase activity;0.0169614492218265!GO:0031625;ubiquitin protein ligase binding;0.0170316156465652!GO:0031647;regulation of protein stability;0.0170952386671196!GO:0030521;androgen receptor signaling pathway;0.0175083549583025!GO:0007034;vacuolar transport;0.0177542285851905!GO:0008320;protein transmembrane transporter activity;0.0181842076614618!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.018577077420511!GO:0008637;apoptotic mitochondrial changes;0.0193279362471708!GO:0031982;vesicle;0.0194858279281679!GO:0019783;small conjugating protein-specific protease activity;0.0198724890058798!GO:0046822;regulation of nucleocytoplasmic transport;0.0199888227827293!GO:0006730;one-carbon compound metabolic process;0.0202323138964535!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0202464615471853!GO:0005774;vacuolar membrane;0.0203910717088795!GO:0005869;dynactin complex;0.0206345708317424!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0208512365800723!GO:0044438;microbody part;0.021480272069708!GO:0044439;peroxisomal part;0.021480272069708!GO:0000096;sulfur amino acid metabolic process;0.0217332717616154!GO:0022884;macromolecule transmembrane transporter activity;0.0217383418735879!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0217383418735879!GO:0019320;hexose catabolic process;0.0218002102359476!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0222214204244399!GO:0010257;NADH dehydrogenase complex assembly;0.0222214204244399!GO:0033108;mitochondrial respiratory chain complex assembly;0.0222214204244399!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0226039085613735!GO:0008144;drug binding;0.0231168098432757!GO:0004526;ribonuclease P activity;0.0231541626632487!GO:0006278;RNA-dependent DNA replication;0.0240155426721285!GO:0043549;regulation of kinase activity;0.0242472489077261!GO:0016023;cytoplasmic membrane-bound vesicle;0.024297700476373!GO:0009081;branched chain family amino acid metabolic process;0.0243823300148588!GO:0006740;NADPH regeneration;0.0244579224003755!GO:0006098;pentose-phosphate shunt;0.0244579224003755!GO:0051090;regulation of transcription factor activity;0.0244579224003755!GO:0043624;cellular protein complex disassembly;0.0248049826556553!GO:0009967;positive regulation of signal transduction;0.0248090970631325!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0253045901540002!GO:0042054;histone methyltransferase activity;0.0253162503132917!GO:0006607;NLS-bearing substrate import into nucleus;0.0253162503132917!GO:0033170;DNA-protein loading ATPase activity;0.025436091712035!GO:0003689;DNA clamp loader activity;0.025436091712035!GO:0051338;regulation of transferase activity;0.0259564424326482!GO:0051656;establishment of organelle localization;0.0260976234277673!GO:0045120;pronucleus;0.0265130710974853!GO:0006301;postreplication repair;0.0268256789397417!GO:0005095;GTPase inhibitor activity;0.027106894228324!GO:0035258;steroid hormone receptor binding;0.0273950670517531!GO:0051287;NAD binding;0.0276396627516886!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0277678337581624!GO:0006672;ceramide metabolic process;0.0278438343326757!GO:0031371;ubiquitin conjugating enzyme complex;0.0282291977748957!GO:0005784;translocon complex;0.0282490958354272!GO:0004843;ubiquitin-specific protease activity;0.0285517304985943!GO:0005851;eukaryotic translation initiation factor 2B complex;0.0286112068415955!GO:0031903;microbody membrane;0.0286558036707462!GO:0005778;peroxisomal membrane;0.0286558036707462!GO:0016788;hydrolase activity, acting on ester bonds;0.0291323043825578!GO:0006266;DNA ligation;0.0292229241511069!GO:0005092;GDP-dissociation inhibitor activity;0.0293642533875817!GO:0030132;clathrin coat of coated pit;0.0295755308704256!GO:0008097;5S rRNA binding;0.0307968955589261!GO:0016569;covalent chromatin modification;0.0308640270026543!GO:0032984;macromolecular complex disassembly;0.0309567946728924!GO:0001832;blastocyst growth;0.032275963092496!GO:0042026;protein refolding;0.0323379324747651!GO:0006354;RNA elongation;0.0324075610919463!GO:0046982;protein heterodimerization activity;0.0335247809968808!GO:0016180;snRNA processing;0.0343289400430775!GO:0016073;snRNA metabolic process;0.0343289400430775!GO:0008537;proteasome activator complex;0.0346172328862729!GO:0006779;porphyrin biosynthetic process;0.0346950876970222!GO:0033014;tetrapyrrole biosynthetic process;0.0346950876970222!GO:0005666;DNA-directed RNA polymerase III complex;0.0347847750370912!GO:0003702;RNA polymerase II transcription factor activity;0.0347847750370912!GO:0043631;RNA polyadenylation;0.0348929539944029!GO:0000209;protein polyubiquitination;0.0351136925696984!GO:0060090;molecular adaptor activity;0.0352562754442724!GO:0030176;integral to endoplasmic reticulum membrane;0.0353486906924488!GO:0005680;anaphase-promoting complex;0.0354877563972136!GO:0006516;glycoprotein catabolic process;0.0355775958736574!GO:0030518;steroid hormone receptor signaling pathway;0.035812785173547!GO:0007050;cell cycle arrest;0.0359766313523807!GO:0044437;vacuolar part;0.0360252267575879!GO:0042158;lipoprotein biosynthetic process;0.0360976401826337!GO:0005765;lysosomal membrane;0.0363825799526533!GO:0004815;aspartate-tRNA ligase activity;0.036468530685779!GO:0006422;aspartyl-tRNA aminoacylation;0.036468530685779!GO:0043621;protein self-association;0.0371902368608669!GO:0006303;double-strand break repair via nonhomologous end joining;0.0375934934391328!GO:0030125;clathrin vesicle coat;0.0375934934391328!GO:0030665;clathrin coated vesicle membrane;0.0375934934391328!GO:0043433;negative regulation of transcription factor activity;0.0377044564516139!GO:0004221;ubiquitin thiolesterase activity;0.037724572349954!GO:0051092;activation of NF-kappaB transcription factor;0.0381625539744711!GO:0019904;protein domain specific binding;0.0381709683226245!GO:0009113;purine base biosynthetic process;0.0385411075488329!GO:0005996;monosaccharide metabolic process;0.038608841225414!GO:0004659;prenyltransferase activity;0.038608841225414!GO:0004428;inositol or phosphatidylinositol kinase activity;0.038608841225414!GO:0019318;hexose metabolic process;0.038608841225414!GO:0042613;MHC class II protein complex;0.038608841225414!GO:0051235;maintenance of localization;0.0390089729139749!GO:0004549;tRNA-specific ribonuclease activity;0.0390248890894922!GO:0030027;lamellipodium;0.039461842824893!GO:0019814;immunoglobulin complex;0.0396556838607533!GO:0019815;B cell receptor complex;0.0396556838607533!GO:0030496;midbody;0.0396556838607533!GO:0045730;respiratory burst;0.0396711210424896!GO:0045859;regulation of protein kinase activity;0.0397934384733367!GO:0030261;chromosome condensation;0.0401537641828184!GO:0003756;protein disulfide isomerase activity;0.0401537641828184!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0401537641828184!GO:0005487;nucleocytoplasmic transporter activity;0.0402886380753391!GO:0003709;RNA polymerase III transcription factor activity;0.0403111118846102!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0403111118846102!GO:0006118;electron transport;0.040732659067476!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0407649355365268!GO:0046649;lymphocyte activation;0.0408361437351999!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0409474951466606!GO:0044262;cellular carbohydrate metabolic process;0.0410006593312769!GO:0031410;cytoplasmic vesicle;0.041308583695593!GO:0040029;regulation of gene expression, epigenetic;0.042073912078695!GO:0017134;fibroblast growth factor binding;0.042073912078695!GO:0008536;Ran GTPase binding;0.0420951159909248!GO:0006096;glycolysis;0.0424373439623474!GO:0032404;mismatch repair complex binding;0.0426896538753803!GO:0006643;membrane lipid metabolic process;0.0446178847670521!GO:0019900;kinase binding;0.0455136875745645!GO:0008299;isoprenoid biosynthetic process;0.0455136875745645!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0459799297259875!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0459799297259875!GO:0033673;negative regulation of kinase activity;0.0460008754130032!GO:0006469;negative regulation of protein kinase activity;0.0460008754130032!GO:0000790;nuclear chromatin;0.0460646557240789!GO:0042769;DNA damage response, detection of DNA damage;0.0461691902263455!GO:0004448;isocitrate dehydrogenase activity;0.0462247491514717!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0465610599109099!GO:0046128;purine ribonucleoside metabolic process;0.0465763766456828!GO:0042278;purine nucleoside metabolic process;0.0465763766456828!GO:0008287;protein serine/threonine phosphatase complex;0.0466218320848864!GO:0016279;protein-lysine N-methyltransferase activity;0.0470958363758011!GO:0018024;histone-lysine N-methyltransferase activity;0.0470958363758011!GO:0016278;lysine N-methyltransferase activity;0.0470958363758011!GO:0030911;TPR domain binding;0.0471041847340046!GO:0000930;gamma-tubulin complex;0.0472891396497244!GO:0005070;SH3/SH2 adaptor activity;0.0475895999484559!GO:0008213;protein amino acid alkylation;0.0475895999484559!GO:0006479;protein amino acid methylation;0.0475895999484559!GO:0000738;DNA catabolic process, exonucleolytic;0.0475895999484559!GO:0005732;small nucleolar ribonucleoprotein complex;0.0477853458947976!GO:0007096;regulation of exit from mitosis;0.0477932072276327!GO:0010458;exit from mitosis;0.0477932072276327!GO:0030262;apoptotic nuclear changes;0.0483509737183206!GO:0008143;poly(A) binding;0.0486957326358643!GO:0009396;folic acid and derivative biosynthetic process;0.0486957326358643!GO:0050178;phenylpyruvate tautomerase activity;0.0487486922255865!GO:0050000;chromosome localization;0.0489132991933991!GO:0051303;establishment of chromosome localization;0.0489132991933991!GO:0006778;porphyrin metabolic process;0.0496057335900231!GO:0033013;tetrapyrrole metabolic process;0.0496057335900231!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0496060533767429!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0496060533767429!GO:0009126;purine nucleoside monophosphate metabolic process;0.0496060533767429!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0496060533767429!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0496060533767429 | |||
|sample_id=10455 | |sample_id=10455 | ||
|sample_note= | |sample_note= | ||
| Line 76: | Line 99: | ||
|sample_tissue=blood | |sample_tissue=blood | ||
|top_motifs=NKX6-1,2:3.15182087592;POU5F1:2.52148876397;RXR{A,B,G}_{NR1H2,PPAR}dimers:2.46552203012;E2F1..5:1.97039044357;MYB:1.90112612097;CDX1,2,4:1.86373495389;VSX1,2:1.831468064;ZBTB16:1.7398790161;FOXP3:1.72759504922;FOXA2:1.68144687546;ELK1,4_GABP{A,B1}:1.63805615515;IKZF2:1.5945115516;PITX1..3:1.48303866012;RXRA_VDR{dimer}:1.46226368228;DMAP1_NCOR{1,2}_SMARC:1.45106749205;HOXA9_MEIS1:1.29959428669;ELF1,2,4:1.28469265857;PAX4:1.25644419918;AIRE:1.2202990802;POU2F1..3:1.12978685693;ZNF143:1.07596560169;BREu{core}:1.04906430407;NFY{A,B,C}:1.04493245492;FOXP1:1.03649866695;OCT4_SOX2{dimer}:1.0354105558;NRF1:1.03289753944;YY1:0.935696041203;PBX1:0.92186355629;CDC5L:0.91282303385;PAX3,7:0.893823976951;NKX2-2,8:0.884762547217;TEF:0.864327358476;EVI1:0.856470653907;GFI1:0.800445852097;HOX{A4,D4}:0.769970156627;PDX1:0.718118149607;HAND1,2:0.69444009715;PAX8:0.694408411057;SPI1:0.669488854245;T:0.667219211278;HES1:0.651094885015;ARID5B:0.641401518667;RORA:0.639925224356;FOXQ1:0.632488202393;RUNX1..3:0.628913702232;BPTF:0.628117563351;IRF1,2:0.579856194746;CUX2:0.568963039955;NFKB1_REL_RELA:0.512284379281;NKX3-1:0.502803079997;SPIB:0.495849072475;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.493025713451;HBP1_HMGB_SSRP1_UBTF:0.483366019002;RBPJ:0.466015955252;SOX{8,9,10}:0.463910568961;ALX1:0.44621530602;MYOD1:0.435912258813;ZNF384:0.386211121708;TOPORS:0.381091137973;POU1F1:0.331082702299;ZEB1:0.313186738967;HSF1,2:0.305702886936;SNAI1..3:0.304178332038;RFX2..5_RFXANK_RFXAP:0.302325164491;ONECUT1,2:0.291647628454;GATA6:0.288008645766;NR5A1,2:0.284866968951;FOXO1,3,4:0.252310198118;LHX3,4:0.202194833537;bHLH_family:0.191721948222;STAT5{A,B}:0.185232823375;TLX2:0.180634836563;NFIL3:0.176325524219;ATF5_CREB3:0.141189363751;ETS1,2:0.127907782019;NKX3-2:0.121851957491;GATA4:0.0898444128612;PAX6:0.0839545538414;HNF4A_NR2F1,2:0.036966272029;SPZ1:0.0144794614144;IRF7:0.0134569810329;PRRX1,2:-0.0040053727582;POU6F1:-0.0303302314707;PPARG:-0.0414605946588;NKX2-3_NKX2-5:-0.0596017490418;MEF2{A,B,C,D}:-0.0705252200845;FOXD3:-0.0739401380587;NANOG{mouse}:-0.0834774707053;AR:-0.0860599678713;NKX2-1,4:-0.086176307118;HOX{A5,B5}:-0.091185871337;UFEwm:-0.105327689316;FOX{I1,J2}:-0.10723800947;FOXN1:-0.115262822801;HOX{A6,A7,B6,B7}:-0.124119187954;CRX:-0.14034573046;KLF4:-0.152147454195;SOX17:-0.157225661363;FOXL1:-0.157734961633;FOXM1:-0.165718992958;TFDP1:-0.169626578568;DBP:-0.172810326621;ADNP_IRX_SIX_ZHX:-0.192110453654;POU3F1..4:-0.207971365726;ESRRA:-0.245005349031;ATF4:-0.247489643348;HMGA1,2:-0.261003267972;ESR1:-0.275104554562;NR6A1:-0.275156126593;MYBL2:-0.319757735679;FOX{F1,F2,J1}:-0.330953485558;HNF1A:-0.339947577962;CREB1:-0.342142129997;RFX1:-0.349777665644;TGIF1:-0.362507311617;RREB1:-0.366845010674;LMO2:-0.399686243688;ALX4:-0.420931690509;AHR_ARNT_ARNT2:-0.433925910993;PRDM1:-0.434632184278;SOX5:-0.446260606203;GCM1,2:-0.448159567353;CEBPA,B_DDIT3:-0.462716159673;PAX2:-0.493100018156;NANOG:-0.496810399386;NR1H4:-0.504226666734;LEF1_TCF7_TCF7L1,2:-0.522546516683;SOX2:-0.544330641182;NHLH1,2:-0.570258690719;ZFP161:-0.572472105271;FOSL2:-0.606575013577;REST:-0.625640671905;EN1,2:-0.64846900146;SREBF1,2:-0.683536719594;NFE2:-0.724954085731;TAL1_TCF{3,4,12}:-0.751662073265;FOS_FOS{B,L1}_JUN{B,D}:-0.764350790555;EBF1:-0.793820092722;ATF2:-0.825401232129;ZNF423:-0.835678705692;BACH2:-0.836677096602;RXR{A,B,G}:-0.851864912337;HLF:-0.852156890877;ZNF148:-0.869917061761;SMAD1..7,9:-0.916664879364;TP53:-0.933933459452;MYFfamily:-0.954897700734;GFI1B:-0.991529675133;PAX1,9:-0.994599161807;ZIC1..3:-1.00984571706;JUN:-1.02107868028;NFATC1..3:-1.0286802135;MZF1:-1.04464626933;HIF1A:-1.04580156099;PATZ1:-1.06475747403;NFE2L2:-1.07480763202;IKZF1:-1.0755316501;GTF2A1,2:-1.08564110064;MAFB:-1.12898822211;MTF1:-1.1523240088;GZF1:-1.17014650625;HMX1:-1.25786962108;MAZ:-1.27579651087;NR3C1:-1.29509390249;TBP:-1.31555340358;MTE{core}:-1.32666952568;EGR1..3:-1.33150214025;FOX{D1,D2}:-1.33154767487;STAT2,4,6:-1.34724519902;STAT1,3:-1.34927256649;XBP1:-1.39264519851;HIC1:-1.40621269136;ZNF238:-1.41041013198;MED-1{core}:-1.41239986774;TLX1..3_NFIC{dimer}:-1.4428598334;NFIX:-1.47218693803;ZBTB6:-1.47810127098;TFAP2{A,C}:-1.47825564351;TEAD1:-1.49576831467;SRF:-1.51211927214;GTF2I:-1.51470634031;SP1:-1.51562016808;TBX4,5:-1.52052964993;XCPE1{core}:-1.53559048492;NFE2L1:-1.54866166249;EP300:-1.55863172568;TFAP2B:-1.64877293088;GLI1..3:-1.66445821699;ATF6:-1.71863547958;TFAP4:-1.87698508083;TFCP2:-1.92811583407;PAX5:-2.05208816939 | |top_motifs=NKX6-1,2:3.15182087592;POU5F1:2.52148876397;RXR{A,B,G}_{NR1H2,PPAR}dimers:2.46552203012;E2F1..5:1.97039044357;MYB:1.90112612097;CDX1,2,4:1.86373495389;VSX1,2:1.831468064;ZBTB16:1.7398790161;FOXP3:1.72759504922;FOXA2:1.68144687546;ELK1,4_GABP{A,B1}:1.63805615515;IKZF2:1.5945115516;PITX1..3:1.48303866012;RXRA_VDR{dimer}:1.46226368228;DMAP1_NCOR{1,2}_SMARC:1.45106749205;HOXA9_MEIS1:1.29959428669;ELF1,2,4:1.28469265857;PAX4:1.25644419918;AIRE:1.2202990802;POU2F1..3:1.12978685693;ZNF143:1.07596560169;BREu{core}:1.04906430407;NFY{A,B,C}:1.04493245492;FOXP1:1.03649866695;OCT4_SOX2{dimer}:1.0354105558;NRF1:1.03289753944;YY1:0.935696041203;PBX1:0.92186355629;CDC5L:0.91282303385;PAX3,7:0.893823976951;NKX2-2,8:0.884762547217;TEF:0.864327358476;EVI1:0.856470653907;GFI1:0.800445852097;HOX{A4,D4}:0.769970156627;PDX1:0.718118149607;HAND1,2:0.69444009715;PAX8:0.694408411057;SPI1:0.669488854245;T:0.667219211278;HES1:0.651094885015;ARID5B:0.641401518667;RORA:0.639925224356;FOXQ1:0.632488202393;RUNX1..3:0.628913702232;BPTF:0.628117563351;IRF1,2:0.579856194746;CUX2:0.568963039955;NFKB1_REL_RELA:0.512284379281;NKX3-1:0.502803079997;SPIB:0.495849072475;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.493025713451;HBP1_HMGB_SSRP1_UBTF:0.483366019002;RBPJ:0.466015955252;SOX{8,9,10}:0.463910568961;ALX1:0.44621530602;MYOD1:0.435912258813;ZNF384:0.386211121708;TOPORS:0.381091137973;POU1F1:0.331082702299;ZEB1:0.313186738967;HSF1,2:0.305702886936;SNAI1..3:0.304178332038;RFX2..5_RFXANK_RFXAP:0.302325164491;ONECUT1,2:0.291647628454;GATA6:0.288008645766;NR5A1,2:0.284866968951;FOXO1,3,4:0.252310198118;LHX3,4:0.202194833537;bHLH_family:0.191721948222;STAT5{A,B}:0.185232823375;TLX2:0.180634836563;NFIL3:0.176325524219;ATF5_CREB3:0.141189363751;ETS1,2:0.127907782019;NKX3-2:0.121851957491;GATA4:0.0898444128612;PAX6:0.0839545538414;HNF4A_NR2F1,2:0.036966272029;SPZ1:0.0144794614144;IRF7:0.0134569810329;PRRX1,2:-0.0040053727582;POU6F1:-0.0303302314707;PPARG:-0.0414605946588;NKX2-3_NKX2-5:-0.0596017490418;MEF2{A,B,C,D}:-0.0705252200845;FOXD3:-0.0739401380587;NANOG{mouse}:-0.0834774707053;AR:-0.0860599678713;NKX2-1,4:-0.086176307118;HOX{A5,B5}:-0.091185871337;UFEwm:-0.105327689316;FOX{I1,J2}:-0.10723800947;FOXN1:-0.115262822801;HOX{A6,A7,B6,B7}:-0.124119187954;CRX:-0.14034573046;KLF4:-0.152147454195;SOX17:-0.157225661363;FOXL1:-0.157734961633;FOXM1:-0.165718992958;TFDP1:-0.169626578568;DBP:-0.172810326621;ADNP_IRX_SIX_ZHX:-0.192110453654;POU3F1..4:-0.207971365726;ESRRA:-0.245005349031;ATF4:-0.247489643348;HMGA1,2:-0.261003267972;ESR1:-0.275104554562;NR6A1:-0.275156126593;MYBL2:-0.319757735679;FOX{F1,F2,J1}:-0.330953485558;HNF1A:-0.339947577962;CREB1:-0.342142129997;RFX1:-0.349777665644;TGIF1:-0.362507311617;RREB1:-0.366845010674;LMO2:-0.399686243688;ALX4:-0.420931690509;AHR_ARNT_ARNT2:-0.433925910993;PRDM1:-0.434632184278;SOX5:-0.446260606203;GCM1,2:-0.448159567353;CEBPA,B_DDIT3:-0.462716159673;PAX2:-0.493100018156;NANOG:-0.496810399386;NR1H4:-0.504226666734;LEF1_TCF7_TCF7L1,2:-0.522546516683;SOX2:-0.544330641182;NHLH1,2:-0.570258690719;ZFP161:-0.572472105271;FOSL2:-0.606575013577;REST:-0.625640671905;EN1,2:-0.64846900146;SREBF1,2:-0.683536719594;NFE2:-0.724954085731;TAL1_TCF{3,4,12}:-0.751662073265;FOS_FOS{B,L1}_JUN{B,D}:-0.764350790555;EBF1:-0.793820092722;ATF2:-0.825401232129;ZNF423:-0.835678705692;BACH2:-0.836677096602;RXR{A,B,G}:-0.851864912337;HLF:-0.852156890877;ZNF148:-0.869917061761;SMAD1..7,9:-0.916664879364;TP53:-0.933933459452;MYFfamily:-0.954897700734;GFI1B:-0.991529675133;PAX1,9:-0.994599161807;ZIC1..3:-1.00984571706;JUN:-1.02107868028;NFATC1..3:-1.0286802135;MZF1:-1.04464626933;HIF1A:-1.04580156099;PATZ1:-1.06475747403;NFE2L2:-1.07480763202;IKZF1:-1.0755316501;GTF2A1,2:-1.08564110064;MAFB:-1.12898822211;MTF1:-1.1523240088;GZF1:-1.17014650625;HMX1:-1.25786962108;MAZ:-1.27579651087;NR3C1:-1.29509390249;TBP:-1.31555340358;MTE{core}:-1.32666952568;EGR1..3:-1.33150214025;FOX{D1,D2}:-1.33154767487;STAT2,4,6:-1.34724519902;STAT1,3:-1.34927256649;XBP1:-1.39264519851;HIC1:-1.40621269136;ZNF238:-1.41041013198;MED-1{core}:-1.41239986774;TLX1..3_NFIC{dimer}:-1.4428598334;NFIX:-1.47218693803;ZBTB6:-1.47810127098;TFAP2{A,C}:-1.47825564351;TEAD1:-1.49576831467;SRF:-1.51211927214;GTF2I:-1.51470634031;SP1:-1.51562016808;TBX4,5:-1.52052964993;XCPE1{core}:-1.53559048492;NFE2L1:-1.54866166249;EP300:-1.55863172568;TFAP2B:-1.64877293088;GLI1..3:-1.66445821699;ATF6:-1.71863547958;TFAP4:-1.87698508083;TFCP2:-1.92811583407;PAX5:-2.05208816939 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10455-106G5;search_select_hide=table117:FF:10455-106G5 | |||
}} | }} | ||
Latest revision as of 14:03, 3 June 2020
| Name: | acute lymphoblastic leukemia (B-ALL) cell line:BALL-1 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs11251 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
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Sample information
RNA information
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11251
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11251
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.024 |
| 10 | 10 | 0.0186 |
| 100 | 100 | 0.0787 |
| 101 | 101 | 0.403 |
| 102 | 102 | 0.992 |
| 103 | 103 | 0.672 |
| 104 | 104 | 0.987 |
| 105 | 105 | 0.614 |
| 106 | 106 | 0.706 |
| 107 | 107 | 0.415 |
| 108 | 108 | 0.762 |
| 109 | 109 | 0.139 |
| 11 | 11 | 0.0746 |
| 110 | 110 | 0.162 |
| 111 | 111 | 0.0402 |
| 112 | 112 | 0.465 |
| 113 | 113 | 0.813 |
| 114 | 114 | 0.967 |
| 115 | 115 | 0.609 |
| 116 | 116 | 0.394 |
| 117 | 117 | 0.0044 |
| 118 | 118 | 0.333 |
| 119 | 119 | 0.255 |
| 12 | 12 | 0.527 |
| 120 | 120 | 0.084 |
| 121 | 121 | 0.574 |
| 122 | 122 | 0.892 |
| 123 | 123 | 0.00124 |
| 124 | 124 | 0.0683 |
| 125 | 125 | 0.0401 |
| 126 | 126 | 0.418 |
| 127 | 127 | 0.864 |
| 128 | 128 | 0.113 |
| 129 | 129 | 0.4 |
| 13 | 13 | 0.0389 |
| 130 | 130 | 0.762 |
| 131 | 131 | 0.242 |
| 132 | 132 | 0.887 |
| 133 | 133 | 0.601 |
| 134 | 134 | 0.464 |
| 135 | 135 | 0.283 |
| 136 | 136 | 0.206 |
| 137 | 137 | 0.155 |
| 138 | 138 | 0.731 |
| 139 | 139 | 0.486 |
| 14 | 14 | 0.824 |
| 140 | 140 | 0.684 |
| 141 | 141 | 0.00765 |
| 142 | 142 | 0.353 |
| 143 | 143 | 0.943 |
| 144 | 144 | 0.722 |
| 145 | 145 | 0.289 |
| 146 | 146 | 0.53 |
| 147 | 147 | 0.084 |
| 148 | 148 | 0.32 |
| 149 | 149 | 0.785 |
| 15 | 15 | 0.181 |
| 150 | 150 | 0.782 |
| 151 | 151 | 0.584 |
| 152 | 152 | 0.0467 |
| 153 | 153 | 0.917 |
| 154 | 154 | 0.616 |
| 155 | 155 | 0.00937 |
| 156 | 156 | 0.813 |
| 157 | 157 | 0.507 |
| 158 | 158 | 0.879 |
| 159 | 159 | 0.386 |
| 16 | 16 | 0.875 |
| 160 | 160 | 0.354 |
| 161 | 161 | 0.239 |
| 162 | 162 | 0.663 |
| 163 | 163 | 0.385 |
| 164 | 164 | 0.131 |
| 165 | 165 | 0.428 |
| 166 | 166 | 0.313 |
| 167 | 167 | 0.111 |
| 168 | 168 | 0.409 |
| 169 | 169 | 0.955 |
| 17 | 17 | 0.975 |
| 18 | 18 | 0.57 |
| 19 | 19 | 0.7 |
| 2 | 2 | 0.15 |
| 20 | 20 | 0.308 |
| 21 | 21 | 0.199 |
| 22 | 22 | 0.742 |
| 23 | 23 | 0.15 |
| 24 | 24 | 0.514 |
| 25 | 25 | 0.148 |
| 26 | 26 | 0.0526 |
| 27 | 27 | 0.956 |
| 28 | 28 | 0.447 |
| 29 | 29 | 0.0205 |
| 3 | 3 | 0.128 |
| 30 | 30 | 0.0511 |
| 31 | 31 | 0.845 |
| 32 | 32 | 0.305 |
| 33 | 33 | 0.587 |
| 34 | 34 | 0.7 |
| 35 | 35 | 0.222 |
| 36 | 36 | 0.0349 |
| 37 | 37 | 0.29 |
| 38 | 38 | 0.785 |
| 39 | 39 | 0.244 |
| 4 | 4 | 0.435 |
| 40 | 40 | 0.151 |
| 41 | 41 | 0.831 |
| 42 | 42 | 0.136 |
| 43 | 43 | 0.465 |
| 44 | 44 | 0.0161 |
| 45 | 45 | 0.303 |
| 46 | 46 | 0.231 |
| 47 | 47 | 0.0447 |
| 48 | 48 | 0.0898 |
| 49 | 49 | 0.16 |
| 5 | 5 | 0.823 |
| 50 | 50 | 0.977 |
| 51 | 51 | 0.806 |
| 52 | 52 | 0.088 |
| 53 | 53 | 0.715 |
| 54 | 54 | 0.83 |
| 55 | 55 | 0.346 |
| 56 | 56 | 0.723 |
| 57 | 57 | 0.0489 |
| 58 | 58 | 0.169 |
| 59 | 59 | 0.828 |
| 6 | 6 | 0.626 |
| 60 | 60 | 0.655 |
| 61 | 61 | 0.0718 |
| 62 | 62 | 0.162 |
| 63 | 63 | 0.785 |
| 64 | 64 | 0.317 |
| 65 | 65 | 0.718 |
| 66 | 66 | 0.16 |
| 67 | 67 | 0.397 |
| 68 | 68 | 0.375 |
| 69 | 69 | 0.954 |
| 7 | 7 | 0.204 |
| 70 | 70 | 0.924 |
| 71 | 71 | 0.0296 |
| 72 | 72 | 0.497 |
| 73 | 73 | 0.869 |
| 74 | 74 | 0.543 |
| 75 | 75 | 0.00244 |
| 76 | 76 | 0.118 |
| 77 | 77 | 0.533 |
| 78 | 78 | 0.201 |
| 79 | 79 | 0.483 |
| 8 | 8 | 0.239 |
| 80 | 80 | 0.559 |
| 81 | 81 | 0.123 |
| 82 | 82 | 0.918 |
| 83 | 83 | 0.882 |
| 84 | 84 | 0.558 |
| 85 | 85 | 0.213 |
| 86 | 86 | 0.389 |
| 87 | 87 | 0.26 |
| 88 | 88 | 0.768 |
| 89 | 89 | 0.62 |
| 9 | 9 | 0.489 |
| 90 | 90 | 0.0152 |
| 91 | 91 | 0.68 |
| 92 | 92 | 0.507 |
| 93 | 93 | 0.853 |
| 94 | 94 | 0.39 |
| 95 | 95 | 0.168 |
| 96 | 96 | 0.903 |
| 97 | 97 | 0.203 |
| 98 | 98 | 0.607 |
| 99 | 99 | 0.409 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11251
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
DOID:12603 acute leukemia
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0102144 acute lymphoblastic leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
12603 (acute leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0102144 (acute lymphoblastic leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0100741 (lymphocytic leukemia cell line sample)
0100773 (lymphoblastoid cell line sample)
0100739 (lymphoblastic leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)
