FF:10828-111C9: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00005964 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007802;DRR008674;DRZ000099;DRZ001484;DRZ011449;DRZ012834 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
| Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M1%2529%2520cell%2520line%253aHYT-1.CNhs13054.10828-111C9.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M1%2529%2520cell%2520line%253aHYT-1.CNhs13054.10828-111C9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M1%2529%2520cell%2520line%253aHYT-1.CNhs13054.10828-111C9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M1%2529%2520cell%2520line%253aHYT-1.CNhs13054.10828-111C9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M1%2529%2520cell%2520line%253aHYT-1.CNhs13054.10828-111C9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10828-111C9 | |id=FF:10828-111C9 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000210;;FF:0101883 | ||
|is_obsolete= | |||
|library_id=CNhs13054 | |||
|library_id_phase_based=2:CNhs13054 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10828 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10828 | |||
|name=acute myeloid leukemia (FAB M1) cell line:HYT-1 | |name=acute myeloid leukemia (FAB M1) cell line:HYT-1 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs13054,LSID1000,release012,COMPLETED | |profile_hcage=CNhs13054,LSID1000,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.076655420403892,0,0,0,0,-0.00700718927860172,0.266395015964697,-0.0657118392649281,0.553520137176469,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0,0,0.395742097014724,0,0,0.330198852338113,0,0,0,0,0,0,0,0,0,0,0,0,-0.126612888968229,0.165886157503144,0,0,0,0,0,0,0,0.326214601685115,0,0,0,0.213523268164062,0,-0.0388251889215059,0,0.116530906921457,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0,0,0,0,0,0.213523268164062,0,0,0,0,0,0,0,0,0,0,-0.0703719563464448,0,0,0,0.0854359079322982,0.408970516607107,0.076655420403892,0,0.0416928196862171,0.0833856393724342,0.25799844492819,0.288327312303075,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0219746461676483,0.0833856393724342,0,0,-0.0702523362953709,-0.238250139713001,0,0,0.11146128891555,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.0833856393724342,0.25799844492819,0,0.0833856393724342,0,0.0833856393724342,0,0,0,0,0,0,0,-0.247178875285564,0,0.471969033710586,-0.0601295031510377,0.0416928196862171,0.0833856393724342,-0.427279086909571,0,0,0,0.0603606617476625,0.153310840807784,0,0.0833856393724342,0,0,-0.128119866952565,0,-0.0504125515893149,0.0416928196862171,0.0833856393724342,0,0,0,-0.305472230898407,0.0833856393724342,-0.0674964270674785,-0.0683442610773682,0,0,0,0,-0.0717863479689027,0,-0.120879483793741,0.312031751187488,-0.221611588102807,-0.303039655428274,-0.04680465889238,0,0,0,-0.623566922266573,-1.01837891339289,0,0,0.329363814970319,-0.139656798874442,0,0.0833856393724342,-0.391044581551635,0,-0.219215767285659,-0.060281105620854,0,0.119952281312406,0,0,0,0,0,0.0833856393724342,0,0,0,0,0,-0.0574934668214365,0.166711396603812,0.143305623263521,0.213523268164062,0.463155442116975,0,-0.402640848873455,0,0,-0.373286155956567,-0.0372130099384495,0,0.404605544174757,0,0.398469518585986,0.149752765255082,-0.36778047450468,0.208951689061469,-0.147401849371139,-0.189981719549847,0,-0.0703719563464448,-0.0177460824326018,0.192953771075429,0.0252117193907133,0.066141906890382,-0.801109480723365,-0.435294021042474,0,0,0,-0.33484475967369,0,0.00883044895916951,-0.406729075104339,-0.0884618715565255,-0.496097108807147,-0.0709360324366821,-0.0357870480533007,0.282329284770562,-0.0395325284566706,0.116798199468867,-0.0210010762251823,-0.243555426820751,0,0.356033796165896,0,-0.0868196327945951,-0.429878310941426,0.274793482769336,0,0.356558968140661,0.145179007086694,0.133197507982349,-0.426162566452572,0.147177344515838,0,0,0.140012645413545,0.266395015964697,0,0,0,0,-0.0719966096620481,-0.225969139671757,-0.0193322933914824,0,-0.0348068246517634,0.0958384770521341,0.109287931033764,0,-0.350244680115345,-0.202170761610805,0,0.485089591904067,0,-0.0437222533861705,0.259679291031897,-0.0116798555312184,0.664630192406431,0.024938812560609,0.28293993502681,0.237674600712269,0.0854359079322982,0.347793856643544,0,-0.00474119310285352,-0.146319219040077,-0.88354475051838,0.392212800593679,0,0.312609883392338,0,-0.265299202920917,0,0.204970576686354,0,0.505355776406287,-0.54043375147324,1.16678321336615,0.12988928591039,0,0.101465574370539,-0.788130937773974,0,-0.239517103757006,-0.0164716176863073,0,-0.150367083334639,-0.697695966512583,-0.169957608178372,-0.138989456679195,0,-0.790080158389657,0,0,-0.138418001745528,0.159275881746516,0.153310840807784,-0.0773125796121356,0.0534086400446282,-0.141060599078319,-0.115971073434934,0.266395015964697,0,-0.56231469862029,0,0,-0.392404795653968,0,-0.353388307993936,0.848491060818578,0,-0.108622809454255,0,0,-0.177527765965176,0.549013443619948,0.116625713439235,0,0.0833856393724342,-0.034731782816954,0,0,0.0416928196862171,0,-0.088504056475733,0.0833856393724342,0.153310840807784,0,0,0,0,0,0.399911784057383,-0.354833330216448,0,-0.0128646887515205,0,0,0,0,0,0,0,0,-0.808415403371336,0.0596845011140522,0.0905058524876421,0.156761501679204,0.0833856393724342,0.0416928196862171,0,-0.13233776318104,0.191515357416181,0.0833856393724342,0.262889213013273,0,0,0,0,0.180254026175486,0,0,0,0,0.155792811110398,0.049428636707828,0,0,0,0.57665462460615,0.0833856393724342,0,0,0,-0.00229468245623288,0,0,-0.00991742582012844,0,-0.0955830460838925,0.00180375982559276,0,-0.21078647687292,0.125777642690194,-0.419000684700447,0,0,0.684708120672707,0,0,0.227862917152814,0.00101541640676789,0,0,0,0,0,0,0.493699993282781,0,0.24884092971722,0,0.0833856393724342,0,0,0,0.493699993282781,0,0,0.0833856393724342,0.0416928196862171,0,-0.625068805573859,-0.00883841728607622,0,0,0,0,0,0,0,-0.0241060230789031,-0.064842796769997,0,0,0.0100298457470123,0,0,0,0,0,0.077587503956706,0,0,0,0.0128385497929855,0,0.116530906921457,0,0.153310840807784,0,0.153310840807784,0.893517006188875,0,0,-0.12405129138573,0,0,0,0,0,0,0.0833856393724342,0,0,0,0,0,0,0.14307592992925,-0.0657118392649281,0,0.153310840807784,0,0,0,0.266395015964697,0,0.0386897051523187,0,0.213523268164062,0,0,-0.113884373708977,0,0,0,0.417440356372739,0,-0.00700718927860172,0,0,0,0,0,0.153310840807784,0.0416928196862171,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0386394401088022,0,-0.28720751597291,0,0,0,-0.232628352633041,0,0,0,0,0,0,0.0103523956576901,0,0,0,0,0,0,0,0.133197507982349,0,0,0,0,0,0,0,0,0,0,0.0833856393724342,0,0,0,0,0,0,-0.0196751077986978,0,0,0,0,0,0,0,0.395742097014724,0,0,-0.0920328098005262,0,0,0.0186421170702822,0.0833856393724342,0,0,-0.109959942573762,-0.283220399823148,-0.0932514166672183,0,0,0.0833856393724342,0.220121149327519,0.213523268164062,0,-0.0482068838774634,0,0.0166082519535329,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0,0,0,0,0,0,0,0,0,0.0416928196862171,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0416928196862171,0,0,0.356033796165896,0,0,0,0.19940555880768,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.106761634082031,0,0,0,0,0,0.383136973848337,0,0,0,-0.213086229657044,0,0,0,0,0,0,0.266395015964697,0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| |||
|rna_box=111 | |rna_box=111 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 57: | Line 78: | ||
|rna_weight_ug=15 | |rna_weight_ug=15 | ||
|sample_age=62 | |sample_age=62 | ||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB1297 | |sample_cell_catalog=RCB1297 | ||
|sample_cell_line=HYT-1 | |sample_cell_line=HYT-1 | ||
| Line 69: | Line 91: | ||
|sample_ethnicity=unknown | |sample_ethnicity=unknown | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.52577887200558e-253!GO:0043227;membrane-bound organelle;4.24632217837093e-230!GO:0043231;intracellular membrane-bound organelle;1.50791827138477e-229!GO:0043226;organelle;1.99319708305283e-214!GO:0043229;intracellular organelle;8.20629404730794e-214!GO:0005737;cytoplasm;3.68056208726357e-142!GO:0044422;organelle part;2.36589673793398e-132!GO:0044446;intracellular organelle part;6.94762500026881e-131!GO:0005634;nucleus;1.8680137000265e-127!GO:0044237;cellular metabolic process;1.43908841467498e-124!GO:0044238;primary metabolic process;1.16771865856162e-122!GO:0043170;macromolecule metabolic process;2.88435520488069e-114!GO:0044444;cytoplasmic part;3.20484244416064e-99!GO:0032991;macromolecular complex;2.39258497826509e-90!GO:0044428;nuclear part;7.89501461418399e-83!GO:0030529;ribonucleoprotein complex;4.09435388484334e-82!GO:0003723;RNA binding;2.61329444321759e-80!GO:0043283;biopolymer metabolic process;2.73770213490346e-80!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;9.90141389073255e-79!GO:0043233;organelle lumen;7.83630590005051e-78!GO:0031974;membrane-enclosed lumen;7.83630590005051e-78!GO:0010467;gene expression;3.11452987173006e-76!GO:0005739;mitochondrion;3.03787751435067e-59!GO:0005515;protein binding;5.6612707484262e-58!GO:0003676;nucleic acid binding;4.66817298668886e-56!GO:0006396;RNA processing;1.50996270147319e-55!GO:0031981;nuclear lumen;1.20368867400326e-51!GO:0006412;translation;1.17858094190533e-48!GO:0005840;ribosome;4.41718801192718e-45!GO:0016070;RNA metabolic process;5.0999203535842e-45!GO:0016071;mRNA metabolic process;9.91691722965486e-45!GO:0043234;protein complex;5.16647833139032e-44!GO:0019538;protein metabolic process;1.03509977652206e-42!GO:0006259;DNA metabolic process;4.97277175034795e-42!GO:0009058;biosynthetic process;5.97429545550664e-42!GO:0044267;cellular protein metabolic process;7.22841106699758e-40!GO:0044429;mitochondrial part;9.87807456928979e-40!GO:0044249;cellular biosynthetic process;1.7521355990297e-39!GO:0044260;cellular macromolecule metabolic process;2.03798158880441e-39!GO:0008380;RNA splicing;5.78969226445123e-39!GO:0003735;structural constituent of ribosome;6.00393684634683e-39!GO:0006397;mRNA processing;1.68016995632917e-38!GO:0031090;organelle membrane;2.07265123998379e-38!GO:0009059;macromolecule biosynthetic process;7.96445889261328e-38!GO:0033036;macromolecule localization;1.42061362563306e-37!GO:0016043;cellular component organization and biogenesis;4.76108780283778e-36!GO:0005829;cytosol;9.19966534599183e-36!GO:0031967;organelle envelope;1.17597814601459e-35!GO:0031975;envelope;2.45813281138002e-35!GO:0015031;protein transport;3.75667366098277e-35!GO:0033279;ribosomal subunit;1.88602536369192e-34!GO:0008104;protein localization;1.28611992373845e-33!GO:0045184;establishment of protein localization;4.92883962772582e-33!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.83624949845891e-32!GO:0005654;nucleoplasm;4.66544879830907e-31!GO:0006996;organelle organization and biogenesis;5.98900252690991e-31!GO:0046907;intracellular transport;1.52410823447524e-30!GO:0065003;macromolecular complex assembly;4.90446863032299e-30!GO:0005681;spliceosome;7.20049683499099e-29!GO:0000166;nucleotide binding;1.34981748749088e-28!GO:0007049;cell cycle;2.01372969253905e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.12632863076263e-27!GO:0006886;intracellular protein transport;1.82464310345472e-26!GO:0022607;cellular component assembly;4.85906495288739e-26!GO:0043228;non-membrane-bound organelle;1.33031364198065e-25!GO:0043232;intracellular non-membrane-bound organelle;1.33031364198065e-25!GO:0044445;cytosolic part;2.16866305321039e-25!GO:0005740;mitochondrial envelope;1.64859265348805e-24!GO:0006974;response to DNA damage stimulus;2.2809585499864e-24!GO:0044451;nucleoplasm part;1.0830327469635e-23!GO:0019866;organelle inner membrane;4.23861803837857e-23!GO:0051649;establishment of cellular localization;6.59539973161893e-23!GO:0022402;cell cycle process;1.44950067933858e-22!GO:0031966;mitochondrial membrane;1.7981541897451e-22!GO:0051641;cellular localization;3.50383734128268e-22!GO:0005694;chromosome;5.68385387394215e-22!GO:0050794;regulation of cellular process;7.4857254070553e-21!GO:0032553;ribonucleotide binding;8.54337212151133e-21!GO:0032555;purine ribonucleotide binding;8.54337212151133e-21!GO:0005730;nucleolus;1.27425543137468e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.46577316765286e-20!GO:0051276;chromosome organization and biogenesis;1.62294136443171e-20!GO:0016462;pyrophosphatase activity;1.69726742125883e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;1.71424004967943e-20!GO:0005743;mitochondrial inner membrane;2.37325865611783e-20!GO:0017076;purine nucleotide binding;2.81631972767656e-20!GO:0006281;DNA repair;3.75316389879798e-20!GO:0017111;nucleoside-triphosphatase activity;3.93294883376148e-20!GO:0044427;chromosomal part;6.39517216233854e-20!GO:0022618;protein-RNA complex assembly;1.92793630522897e-19!GO:0006119;oxidative phosphorylation;2.13061974392376e-19!GO:0015935;small ribosomal subunit;5.03542242687873e-19!GO:0032559;adenyl ribonucleotide binding;5.10736392262642e-19!GO:0005524;ATP binding;5.117235719811e-19!GO:0019222;regulation of metabolic process;8.12967561078876e-19!GO:0000278;mitotic cell cycle;8.59875856540779e-19!GO:0006457;protein folding;1.44536610061193e-18!GO:0031980;mitochondrial lumen;2.05037311011889e-18!GO:0005759;mitochondrial matrix;2.05037311011889e-18!GO:0030554;adenyl nucleotide binding;2.8582374768503e-18!GO:0008134;transcription factor binding;9.35627375301032e-18!GO:0044455;mitochondrial membrane part;1.7024793195322e-17!GO:0006325;establishment and/or maintenance of chromatin architecture;2.73865108605356e-17!GO:0016874;ligase activity;4.91419384010463e-17!GO:0009719;response to endogenous stimulus;4.92630232880694e-17!GO:0006323;DNA packaging;7.58017523925126e-17!GO:0044265;cellular macromolecule catabolic process;1.43771639149243e-16!GO:0006605;protein targeting;1.57566358192365e-16!GO:0031323;regulation of cellular metabolic process;1.67615303464748e-16!GO:0015934;large ribosomal subunit;2.74241957683871e-16!GO:0048770;pigment granule;5.11640472479578e-16!GO:0042470;melanosome;5.11640472479578e-16!GO:0012505;endomembrane system;7.05057848674467e-16!GO:0006512;ubiquitin cycle;1.13137633145379e-15!GO:0016887;ATPase activity;1.56607400806895e-15!GO:0042623;ATPase activity, coupled;1.87111571882121e-15!GO:0043412;biopolymer modification;1.93635870481599e-15!GO:0022403;cell cycle phase;2.02563418600407e-15!GO:0008135;translation factor activity, nucleic acid binding;2.05885955483852e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.08074078393315e-15!GO:0016604;nuclear body;3.06933401622383e-15!GO:0006350;transcription;6.06863056947962e-15!GO:0012501;programmed cell death;6.40585598541465e-15!GO:0006915;apoptosis;6.54054354378945e-15!GO:0050789;regulation of biological process;1.18605656128608e-14!GO:0006913;nucleocytoplasmic transport;1.51658899594901e-14!GO:0051169;nuclear transport;3.84772572175801e-14!GO:0044248;cellular catabolic process;4.15509541705741e-14!GO:0010468;regulation of gene expression;4.23340680086516e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;4.78833094264702e-14!GO:0000375;RNA splicing, via transesterification reactions;4.78833094264702e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;4.78833094264702e-14!GO:0051726;regulation of cell cycle;7.1678565965731e-14!GO:0042254;ribosome biogenesis and assembly;1.08700365685161e-13!GO:0006260;DNA replication;1.08891695431515e-13!GO:0008219;cell death;1.21848946230806e-13!GO:0016265;death;1.21848946230806e-13!GO:0005746;mitochondrial respiratory chain;1.30303244539021e-13!GO:0000785;chromatin;1.38990845411481e-13!GO:0000074;regulation of progression through cell cycle;1.39446673474788e-13!GO:0051603;proteolysis involved in cellular protein catabolic process;2.34463456673489e-13!GO:0019941;modification-dependent protein catabolic process;2.54804849821266e-13!GO:0043632;modification-dependent macromolecule catabolic process;2.54804849821266e-13!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.58599736519245e-13!GO:0044453;nuclear membrane part;2.75509102803148e-13!GO:0006511;ubiquitin-dependent protein catabolic process;3.18212298866238e-13!GO:0000087;M phase of mitotic cell cycle;3.25458884928554e-13!GO:0043285;biopolymer catabolic process;3.6663727487715e-13!GO:0009057;macromolecule catabolic process;4.5023482433842e-13!GO:0044257;cellular protein catabolic process;4.8693064325489e-13!GO:0006464;protein modification process;5.16820855085292e-13!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;7.76952049305403e-13!GO:0007067;mitosis;8.42407818315646e-13!GO:0044432;endoplasmic reticulum part;1.15159394871014e-12!GO:0003743;translation initiation factor activity;1.1736338783616e-12!GO:0051082;unfolded protein binding;1.26827059317837e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.30585525991875e-12!GO:0016568;chromatin modification;1.71295276740408e-12!GO:0050136;NADH dehydrogenase (quinone) activity;1.71868088365236e-12!GO:0003954;NADH dehydrogenase activity;1.71868088365236e-12!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.71868088365236e-12!GO:0051186;cofactor metabolic process;1.87697711948999e-12!GO:0005635;nuclear envelope;2.02376505689959e-12!GO:0031965;nuclear membrane;2.44668898911561e-12!GO:0006413;translational initiation;2.73232230312375e-12!GO:0032774;RNA biosynthetic process;2.94186780073351e-12!GO:0016607;nuclear speck;3.26502153257463e-12!GO:0017038;protein import;3.3092846815685e-12!GO:0051301;cell division;3.59097376820977e-12!GO:0006351;transcription, DNA-dependent;3.97936701762041e-12!GO:0003677;DNA binding;6.51516377567547e-12!GO:0000502;proteasome complex (sensu Eukaryota);1.12881101432381e-11!GO:0043687;post-translational protein modification;1.22192899588681e-11!GO:0005783;endoplasmic reticulum;1.62487815102803e-11!GO:0005761;mitochondrial ribosome;3.00310605124829e-11!GO:0000313;organellar ribosome;3.00310605124829e-11!GO:0000279;M phase;3.19003246348497e-11!GO:0045449;regulation of transcription;3.60151814417125e-11!GO:0004386;helicase activity;4.46167469056935e-11!GO:0065007;biological regulation;5.04197282692243e-11!GO:0065004;protein-DNA complex assembly;6.19586610691112e-11!GO:0006446;regulation of translational initiation;6.71706196134336e-11!GO:0003712;transcription cofactor activity;7.08745422345902e-11!GO:0042775;organelle ATP synthesis coupled electron transport;7.86437528644016e-11!GO:0042773;ATP synthesis coupled electron transport;7.86437528644016e-11!GO:0006333;chromatin assembly or disassembly;9.95423451305968e-11!GO:0030964;NADH dehydrogenase complex (quinone);9.95423451305968e-11!GO:0045271;respiratory chain complex I;9.95423451305968e-11!GO:0005747;mitochondrial respiratory chain complex I;9.95423451305968e-11!GO:0006732;coenzyme metabolic process;1.52216110985255e-10!GO:0006403;RNA localization;1.86104126232753e-10!GO:0005643;nuclear pore;2.05376269497826e-10!GO:0006399;tRNA metabolic process;2.24042435412091e-10!GO:0050657;nucleic acid transport;2.35308711503654e-10!GO:0051236;establishment of RNA localization;2.35308711503654e-10!GO:0050658;RNA transport;2.35308711503654e-10!GO:0048193;Golgi vesicle transport;2.50767877929684e-10!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.57216390382397e-10!GO:0006163;purine nucleotide metabolic process;3.41555900348134e-10!GO:0006164;purine nucleotide biosynthetic process;4.09758447457138e-10!GO:0008026;ATP-dependent helicase activity;4.14139989565734e-10!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;6.43595116100592e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;6.543749168715e-10!GO:0005789;endoplasmic reticulum membrane;1.14502389469279e-09!GO:0030163;protein catabolic process;1.15902974492687e-09!GO:0042981;regulation of apoptosis;1.19530129111751e-09!GO:0016192;vesicle-mediated transport;1.41680945866685e-09!GO:0006355;regulation of transcription, DNA-dependent;1.41680945866685e-09!GO:0051170;nuclear import;1.45929665686016e-09!GO:0006366;transcription from RNA polymerase II promoter;1.57326624948182e-09!GO:0043067;regulation of programmed cell death;1.81715839769769e-09!GO:0009259;ribonucleotide metabolic process;1.98087347313448e-09!GO:0009150;purine ribonucleotide metabolic process;2.51844794891195e-09!GO:0009152;purine ribonucleotide biosynthetic process;3.04095370513243e-09!GO:0006793;phosphorus metabolic process;3.1219315870226e-09!GO:0006796;phosphate metabolic process;3.1219315870226e-09!GO:0016072;rRNA metabolic process;3.6598125793555e-09!GO:0006606;protein import into nucleus;4.27972728018876e-09!GO:0006364;rRNA processing;4.58913244475572e-09!GO:0065002;intracellular protein transport across a membrane;4.82495431025555e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;4.88190782536099e-09!GO:0008565;protein transporter activity;5.16652975392553e-09!GO:0009260;ribonucleotide biosynthetic process;5.68397264841352e-09!GO:0046930;pore complex;7.05028741584907e-09!GO:0043566;structure-specific DNA binding;7.71501728702518e-09!GO:0016310;phosphorylation;9.34031641111168e-09!GO:0009055;electron carrier activity;9.36455975806849e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;9.4641142617874e-09!GO:0051028;mRNA transport;9.89008108646896e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.48909427668714e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.64014700185224e-08!GO:0019829;cation-transporting ATPase activity;1.82279257365328e-08!GO:0003697;single-stranded DNA binding;4.3003555606255e-08!GO:0015986;ATP synthesis coupled proton transport;5.05698146105316e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;5.05698146105316e-08!GO:0048523;negative regulation of cellular process;5.32644869368453e-08!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;6.27195340626925e-08!GO:0004812;aminoacyl-tRNA ligase activity;6.27195340626925e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;6.27195340626925e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;6.43987014512737e-08!GO:0006334;nucleosome assembly;8.88082940944882e-08!GO:0043038;amino acid activation;8.99722592216043e-08!GO:0006418;tRNA aminoacylation for protein translation;8.99722592216043e-08!GO:0043039;tRNA aminoacylation;8.99722592216043e-08!GO:0051329;interphase of mitotic cell cycle;1.00799653550746e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.20186627688664e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.27742696557852e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.27742696557852e-07!GO:0005794;Golgi apparatus;1.28452314023198e-07!GO:0031497;chromatin assembly;1.30745036741853e-07!GO:0051325;interphase;1.43518428050224e-07!GO:0009056;catabolic process;1.69072155518207e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.74153248119935e-07!GO:0009141;nucleoside triphosphate metabolic process;1.79560677023313e-07!GO:0008639;small protein conjugating enzyme activity;1.98260506643088e-07!GO:0016740;transferase activity;1.99618751846047e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.45565195637088e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.45565195637088e-07!GO:0051188;cofactor biosynthetic process;2.50288740451069e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.80434846264089e-07!GO:0006261;DNA-dependent DNA replication;2.84822195455389e-07!GO:0015078;hydrogen ion transmembrane transporter activity;3.21936513392824e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.21936513392824e-07!GO:0009144;purine nucleoside triphosphate metabolic process;3.21936513392824e-07!GO:0016779;nucleotidyltransferase activity;3.40510491385549e-07!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.47498640490146e-07!GO:0006754;ATP biosynthetic process;3.68502263589219e-07!GO:0006753;nucleoside phosphate metabolic process;3.68502263589219e-07!GO:0009060;aerobic respiration;3.87108461887657e-07!GO:0004842;ubiquitin-protein ligase activity;3.96479016156401e-07!GO:0019899;enzyme binding;4.171301574256e-07!GO:0006752;group transfer coenzyme metabolic process;4.19616283093459e-07!GO:0003713;transcription coactivator activity;4.67532410359576e-07!GO:0051246;regulation of protein metabolic process;5.63524035124016e-07!GO:0043069;negative regulation of programmed cell death;6.45332242200426e-07!GO:0043066;negative regulation of apoptosis;6.90194312379838e-07!GO:0046034;ATP metabolic process;7.22685278163254e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;7.5875468423123e-07!GO:0007005;mitochondrion organization and biogenesis;7.7645292474393e-07!GO:0016564;transcription repressor activity;8.28521608593292e-07!GO:0006916;anti-apoptosis;9.06064945703606e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;9.84780529790328e-07!GO:0019787;small conjugating protein ligase activity;9.90140695851735e-07!GO:0048519;negative regulation of biological process;1.28947702040544e-06!GO:0000245;spliceosome assembly;1.32765576809751e-06!GO:0045786;negative regulation of progression through cell cycle;1.38089233898928e-06!GO:0006084;acetyl-CoA metabolic process;1.63327634664316e-06!GO:0016563;transcription activator activity;1.68399777724374e-06!GO:0006099;tricarboxylic acid cycle;1.69243077566692e-06!GO:0046356;acetyl-CoA catabolic process;1.69243077566692e-06!GO:0016363;nuclear matrix;2.08012686134844e-06!GO:0000075;cell cycle checkpoint;2.21539489689203e-06!GO:0009117;nucleotide metabolic process;2.37903004969312e-06!GO:0045333;cellular respiration;2.37903004969312e-06!GO:0016787;hydrolase activity;2.68110607775566e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.8894124857008e-06!GO:0005813;centrosome;2.93580836580661e-06!GO:0045259;proton-transporting ATP synthase complex;3.26331317563799e-06!GO:0005793;ER-Golgi intermediate compartment;3.33632663282495e-06!GO:0006461;protein complex assembly;3.65685609647986e-06!GO:0009108;coenzyme biosynthetic process;4.04845328262842e-06!GO:0009109;coenzyme catabolic process;4.12575545608631e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;4.94389431754956e-06!GO:0006950;response to stress;5.27776834349342e-06!GO:0007243;protein kinase cascade;5.99005053848111e-06!GO:0005815;microtubule organizing center;6.95941588993928e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;8.12190220420949e-06!GO:0015399;primary active transmembrane transporter activity;8.12190220420949e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;8.49035652500973e-06!GO:0051187;cofactor catabolic process;8.64033382807936e-06!GO:0003690;double-stranded DNA binding;8.64033382807936e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;9.01693455555092e-06!GO:0008270;zinc ion binding;9.19591937473995e-06!GO:0030120;vesicle coat;9.52035413297026e-06!GO:0030662;coated vesicle membrane;9.52035413297026e-06!GO:0006888;ER to Golgi vesicle-mediated transport;1.08939666840851e-05!GO:0006613;cotranslational protein targeting to membrane;1.09265611260279e-05!GO:0003724;RNA helicase activity;1.09498402439669e-05!GO:0005839;proteasome core complex (sensu Eukaryota);1.13519732198434e-05!GO:0016881;acid-amino acid ligase activity;1.14462441479085e-05!GO:0065009;regulation of a molecular function;1.33809976464539e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.37931534190042e-05!GO:0000775;chromosome, pericentric region;1.40163727034885e-05!GO:0015630;microtubule cytoskeleton;1.45587220406453e-05!GO:0032446;protein modification by small protein conjugation;1.68567906054435e-05!GO:0048475;coated membrane;1.71350678384177e-05!GO:0030117;membrane coat;1.71350678384177e-05!GO:0006310;DNA recombination;2.14308000086254e-05!GO:0005667;transcription factor complex;2.23767686252249e-05!GO:0005768;endosome;2.27477222119596e-05!GO:0005819;spindle;2.63171760182552e-05!GO:0003899;DNA-directed RNA polymerase activity;2.6629000680278e-05!GO:0031324;negative regulation of cellular metabolic process;2.74155502231826e-05!GO:0003729;mRNA binding;3.43708304033628e-05!GO:0016567;protein ubiquitination;3.86029818732623e-05!GO:0004298;threonine endopeptidase activity;5.25843465260296e-05!GO:0051168;nuclear export;5.29712357294107e-05!GO:0000786;nucleosome;5.54050038438648e-05!GO:0000082;G1/S transition of mitotic cell cycle;5.61438369295351e-05!GO:0043021;ribonucleoprotein binding;5.80295731379465e-05!GO:0051427;hormone receptor binding;5.96355835706828e-05!GO:0008094;DNA-dependent ATPase activity;6.03725748783605e-05!GO:0006401;RNA catabolic process;8.9139835619463e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;8.94472642548491e-05!GO:0043492;ATPase activity, coupled to movement of substances;9.50779547679294e-05!GO:0035257;nuclear hormone receptor binding;9.85063802054933e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000106898667953264!GO:0016853;isomerase activity;0.00010946415839932!GO:0005657;replication fork;0.000115892032301564!GO:0046914;transition metal ion binding;0.000116426664239556!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00011760346565472!GO:0007051;spindle organization and biogenesis;0.000125916568331218!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.00012709222289306!GO:0016491;oxidoreductase activity;0.000129227432714925!GO:0003714;transcription corepressor activity;0.000142463838668396!GO:0019843;rRNA binding;0.000142463838668396!GO:0006302;double-strand break repair;0.000142463838668396!GO:0000151;ubiquitin ligase complex;0.000143081211610452!GO:0009165;nucleotide biosynthetic process;0.000147092975760899!GO:0005525;GTP binding;0.000161521304976942!GO:0045454;cell redox homeostasis;0.000181572032349703!GO:0019752;carboxylic acid metabolic process;0.000186295735883471!GO:0043623;cellular protein complex assembly;0.000187958264797083!GO:0005770;late endosome;0.000188299623864274!GO:0006612;protein targeting to membrane;0.000190398933510781!GO:0000776;kinetochore;0.000209953193068025!GO:0044452;nucleolar part;0.000212391748590514!GO:0006082;organic acid metabolic process;0.000215306218565722!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000248359815960005!GO:0042802;identical protein binding;0.000249660317296935!GO:0008186;RNA-dependent ATPase activity;0.000259267115451227!GO:0006352;transcription initiation;0.000291089728571029!GO:0030880;RNA polymerase complex;0.000292493546509435!GO:0005885;Arp2/3 protein complex;0.000293724287139206!GO:0003924;GTPase activity;0.000299646298347781!GO:0009892;negative regulation of metabolic process;0.000325142374108202!GO:0006402;mRNA catabolic process;0.000325481490302292!GO:0043681;protein import into mitochondrion;0.000355200619245019!GO:0005637;nuclear inner membrane;0.000414850076326759!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000436624031672908!GO:0006414;translational elongation;0.000437248572068837!GO:0008632;apoptotic program;0.000459930670902545!GO:0005788;endoplasmic reticulum lumen;0.000463747488454456!GO:0003682;chromatin binding;0.000466751847194447!GO:0007088;regulation of mitosis;0.000466751847194447!GO:0031982;vesicle;0.000474605319964995!GO:0007006;mitochondrial membrane organization and biogenesis;0.000499035210033253!GO:0031072;heat shock protein binding;0.000512581570518923!GO:0005762;mitochondrial large ribosomal subunit;0.000520596270684992!GO:0000315;organellar large ribosomal subunit;0.000520596270684992!GO:0006839;mitochondrial transport;0.000536500251832345!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000560747477387205!GO:0016741;transferase activity, transferring one-carbon groups;0.000561230665959074!GO:0006818;hydrogen transport;0.000574989752263401!GO:0005798;Golgi-associated vesicle;0.000579358312829219!GO:0031968;organelle outer membrane;0.00057992587894761!GO:0003684;damaged DNA binding;0.000593519153995843!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000600007164283933!GO:0008033;tRNA processing;0.000631389127658208!GO:0043065;positive regulation of apoptosis;0.000643487662595525!GO:0019867;outer membrane;0.000650256822547316!GO:0008654;phospholipid biosynthetic process;0.000654836312634108!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000657165164895019!GO:0000428;DNA-directed RNA polymerase complex;0.000657165164895019!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000659007287569618!GO:0046822;regulation of nucleocytoplasmic transport;0.000670184719819723!GO:0015992;proton transport;0.000670184719819723!GO:0003678;DNA helicase activity;0.000683717551737387!GO:0008168;methyltransferase activity;0.000692374810090217!GO:0016481;negative regulation of transcription;0.000692374810090217!GO:0043068;positive regulation of programmed cell death;0.000746428356465188!GO:0004004;ATP-dependent RNA helicase activity;0.000776202812705124!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000781726099685063!GO:0000049;tRNA binding;0.000862464903252136!GO:0016859;cis-trans isomerase activity;0.000901340678296834!GO:0016126;sterol biosynthetic process;0.0010098549403832!GO:0006383;transcription from RNA polymerase III promoter;0.00103597111998069!GO:0004674;protein serine/threonine kinase activity;0.00105826643210841!GO:0048522;positive regulation of cellular process;0.00106795056482615!GO:0044431;Golgi apparatus part;0.00107499757831838!GO:0051087;chaperone binding;0.00107775497687086!GO:0005741;mitochondrial outer membrane;0.00111207867726672!GO:0000059;protein import into nucleus, docking;0.00116237793092058!GO:0051252;regulation of RNA metabolic process;0.0011632268323379!GO:0007093;mitotic cell cycle checkpoint;0.0011632268323379!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00126360471429067!GO:0047485;protein N-terminus binding;0.00127384453694424!GO:0050790;regulation of catalytic activity;0.00128082611068117!GO:0031410;cytoplasmic vesicle;0.00132006694958193!GO:0032508;DNA duplex unwinding;0.00132894459560261!GO:0032392;DNA geometric change;0.00132894459560261!GO:0031988;membrane-bound vesicle;0.00134542228961991!GO:0051052;regulation of DNA metabolic process;0.00139219503907805!GO:0007050;cell cycle arrest;0.00145319149925154!GO:0006520;amino acid metabolic process;0.00145907111379443!GO:0006417;regulation of translation;0.00146157294720138!GO:0006091;generation of precursor metabolites and energy;0.0014649901849256!GO:0005773;vacuole;0.00146871020198333!GO:0051789;response to protein stimulus;0.00148405203916736!GO:0006986;response to unfolded protein;0.00148405203916736!GO:0051920;peroxiredoxin activity;0.00152003454683176!GO:0006917;induction of apoptosis;0.00163385240511796!GO:0032561;guanyl ribonucleotide binding;0.00171719007897136!GO:0019001;guanyl nucleotide binding;0.00171719007897136!GO:0000922;spindle pole;0.00189773340886423!GO:0006695;cholesterol biosynthetic process;0.0019771524441289!GO:0000323;lytic vacuole;0.00199564149380298!GO:0005764;lysosome;0.00199564149380298!GO:0030384;phosphoinositide metabolic process;0.0020055428021151!GO:0046983;protein dimerization activity;0.00200645640292019!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00208311716508077!GO:0000314;organellar small ribosomal subunit;0.00212317603175258!GO:0005763;mitochondrial small ribosomal subunit;0.00212317603175258!GO:0044440;endosomal part;0.00212858193988439!GO:0010008;endosome membrane;0.00212858193988439!GO:0005684;U2-dependent spliceosome;0.00215987065254295!GO:0012502;induction of programmed cell death;0.00219078652017752!GO:0043414;biopolymer methylation;0.00231151046280586!GO:0004527;exonuclease activity;0.00234254698644199!GO:0043488;regulation of mRNA stability;0.00243883034579939!GO:0043487;regulation of RNA stability;0.00243883034579939!GO:0051098;regulation of binding;0.00243883034579939!GO:0006268;DNA unwinding during replication;0.00258456433302432!GO:0006626;protein targeting to mitochondrion;0.00262205103870644!GO:0006405;RNA export from nucleus;0.00263085347686064!GO:0005048;signal sequence binding;0.00268017477264912!GO:0004518;nuclease activity;0.002717468142119!GO:0032259;methylation;0.0027445854724839!GO:0022890;inorganic cation transmembrane transporter activity;0.00283254271532281!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00290492246623767!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00290492246623767!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00290492246623767!GO:0007059;chromosome segregation;0.00291157006334783!GO:0048500;signal recognition particle;0.00297521731346315!GO:0032200;telomere organization and biogenesis;0.00308119797364981!GO:0000723;telomere maintenance;0.00308119797364981!GO:0000287;magnesium ion binding;0.00314845922724695!GO:0006607;NLS-bearing substrate import into nucleus;0.0031628407126231!GO:0015980;energy derivation by oxidation of organic compounds;0.0031844674089313!GO:0008610;lipid biosynthetic process;0.00327138227929586!GO:0042393;histone binding;0.00331237863850522!GO:0006338;chromatin remodeling;0.00337699643094138!GO:0030867;rough endoplasmic reticulum membrane;0.00357942714012839!GO:0016023;cytoplasmic membrane-bound vesicle;0.00364198126464609!GO:0006650;glycerophospholipid metabolic process;0.00383436540981512!GO:0007242;intracellular signaling cascade;0.00387661118481227!GO:0046483;heterocycle metabolic process;0.00411659773753087!GO:0016251;general RNA polymerase II transcription factor activity;0.00441239215530986!GO:0008139;nuclear localization sequence binding;0.00444091220791134!GO:0000096;sulfur amino acid metabolic process;0.00452440279242019!GO:0030663;COPI coated vesicle membrane;0.00465560687507934!GO:0030126;COPI vesicle coat;0.00465560687507934!GO:0030658;transport vesicle membrane;0.00468271599957128!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00472410406675073!GO:0007052;mitotic spindle organization and biogenesis;0.00472993619110567!GO:0009112;nucleobase metabolic process;0.00479478114894018!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00479478114894018!GO:0000118;histone deacetylase complex;0.00481133817472832!GO:0006284;base-excision repair;0.00484051915077514!GO:0051235;maintenance of localization;0.00491526515245433!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00550344173419547!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00550344173419547!GO:0006595;polyamine metabolic process;0.00555684591127808!GO:0008047;enzyme activator activity;0.00555684591127808!GO:0051223;regulation of protein transport;0.00560781905047085!GO:0005769;early endosome;0.00565855107676463!GO:0051287;NAD binding;0.00577136355987721!GO:0015036;disulfide oxidoreductase activity;0.00578809232788229!GO:0035258;steroid hormone receptor binding;0.00608020689231469!GO:0043284;biopolymer biosynthetic process;0.00613145304033094!GO:0008652;amino acid biosynthetic process;0.00620751634075312!GO:0045185;maintenance of protein localization;0.00631388240018089!GO:0031326;regulation of cellular biosynthetic process;0.00636509521491611!GO:0031252;leading edge;0.00657024302767639!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00663092296850538!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00700112185532573!GO:0045047;protein targeting to ER;0.00700112185532573!GO:0009967;positive regulation of signal transduction;0.00713040826835086!GO:0008312;7S RNA binding;0.00716661435492671!GO:0016197;endosome transport;0.00740598631262254!GO:0006891;intra-Golgi vesicle-mediated transport;0.00740598631262254!GO:0030134;ER to Golgi transport vesicle;0.00758209839295446!GO:0016584;nucleosome positioning;0.00759302881255228!GO:0000139;Golgi membrane;0.00759302881255228!GO:0040029;regulation of gene expression, epigenetic;0.0076215122083902!GO:0030127;COPII vesicle coat;0.00763783331972313!GO:0012507;ER to Golgi transport vesicle membrane;0.00763783331972313!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00772476126144987!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00772952438539931!GO:0050662;coenzyme binding;0.00789421664673891!GO:0031124;mRNA 3'-end processing;0.0080853773063151!GO:0015631;tubulin binding;0.00829504990210226!GO:0022415;viral reproductive process;0.00832142870741184!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00841645990096636!GO:0008276;protein methyltransferase activity;0.00850371514598139!GO:0007040;lysosome organization and biogenesis;0.00913076717493502!GO:0031625;ubiquitin protein ligase binding;0.0093411628551939!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00942137149041921!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00954278977038637!GO:0051101;regulation of DNA binding;0.00959146647738933!GO:0032507;maintenance of cellular protein localization;0.00982415075873285!GO:0003711;transcription elongation regulator activity;0.0098767132730482!GO:0006144;purine base metabolic process;0.0109176560337107!GO:0044262;cellular carbohydrate metabolic process;0.0109867444162934!GO:0030660;Golgi-associated vesicle membrane;0.0110545025299087!GO:0042770;DNA damage response, signal transduction;0.0113777085356968!GO:0007034;vacuolar transport;0.0115962476915964!GO:0003725;double-stranded RNA binding;0.0117836364690887!GO:0033157;regulation of intracellular protein transport;0.0124379010066062!GO:0042306;regulation of protein import into nucleus;0.0124379010066062!GO:0000339;RNA cap binding;0.0124645972133583!GO:0033673;negative regulation of kinase activity;0.0125599601928128!GO:0006469;negative regulation of protein kinase activity;0.0125599601928128!GO:0060090;molecular adaptor activity;0.0126766836905469!GO:0045045;secretory pathway;0.01271267263207!GO:0006270;DNA replication initiation;0.0127138669852938!GO:0006289;nucleotide-excision repair;0.0127653794825968!GO:0005832;chaperonin-containing T-complex;0.0128343326493731!GO:0051059;NF-kappaB binding;0.0129561411665071!GO:0008234;cysteine-type peptidase activity;0.0134421353456094!GO:0018193;peptidyl-amino acid modification;0.0134464102430999!GO:0043433;negative regulation of transcription factor activity;0.013997586543851!GO:0007021;tubulin folding;0.0146437446001628!GO:0048518;positive regulation of biological process;0.0147671068730269!GO:0044438;microbody part;0.0147671068730269!GO:0044439;peroxisomal part;0.0147671068730269!GO:0048471;perinuclear region of cytoplasm;0.0151452508637103!GO:0006378;mRNA polyadenylation;0.0153085668995216!GO:0030137;COPI-coated vesicle;0.0153227832174794!GO:0008629;induction of apoptosis by intracellular signals;0.0154816993021014!GO:0051348;negative regulation of transferase activity;0.0158169282028503!GO:0051338;regulation of transferase activity;0.0158169282028503!GO:0009303;rRNA transcription;0.0161096440850947!GO:0004576;oligosaccharyl transferase activity;0.0161843385955904!GO:0006376;mRNA splice site selection;0.0163719460639285!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0163719460639285!GO:0019210;kinase inhibitor activity;0.0167576267400139!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0170289024928683!GO:0008637;apoptotic mitochondrial changes;0.0170289024928683!GO:0000097;sulfur amino acid biosynthetic process;0.0170289024928683!GO:0007033;vacuole organization and biogenesis;0.0171395355999197!GO:0051539;4 iron, 4 sulfur cluster binding;0.0172598877424032!GO:0043549;regulation of kinase activity;0.0173733358073692!GO:0004860;protein kinase inhibitor activity;0.0175574493104489!GO:0006519;amino acid and derivative metabolic process;0.0176087157056644!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0178407855560389!GO:0009889;regulation of biosynthetic process;0.0178559601901834!GO:0051651;maintenance of cellular localization;0.0179718399723321!GO:0046489;phosphoinositide biosynthetic process;0.0181932408604284!GO:0032940;secretion by cell;0.0182891941121578!GO:0043022;ribosome binding;0.018938807361178!GO:0000781;chromosome, telomeric region;0.0190937865095403!GO:0000123;histone acetyltransferase complex;0.0191314802484748!GO:0031123;RNA 3'-end processing;0.0191486837046687!GO:0030041;actin filament polymerization;0.0191486837046687!GO:0046474;glycerophospholipid biosynthetic process;0.0191675185331205!GO:0006730;one-carbon compound metabolic process;0.0191770667647472!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0191770667647472!GO:0008097;5S rRNA binding;0.0196183653197228!GO:0046467;membrane lipid biosynthetic process;0.0196805438140297!GO:0005669;transcription factor TFIID complex;0.0201309611872864!GO:0030521;androgen receptor signaling pathway;0.0208739192149693!GO:0009266;response to temperature stimulus;0.0208739192149693!GO:0003702;RNA polymerase II transcription factor activity;0.0208739192149693!GO:0031903;microbody membrane;0.0209894170614028!GO:0005778;peroxisomal membrane;0.0209894170614028!GO:0006672;ceramide metabolic process;0.0211330636232957!GO:0004003;ATP-dependent DNA helicase activity;0.0212843151893148!GO:0006611;protein export from nucleus;0.0212919954493339!GO:0016272;prefoldin complex;0.0213053868488012!GO:0008250;oligosaccharyl transferase complex;0.0218870564911155!GO:0009615;response to virus;0.0219621791556835!GO:0009451;RNA modification;0.0220545938546418!GO:0006275;regulation of DNA replication;0.0221028722325697!GO:0004448;isocitrate dehydrogenase activity;0.0222412408897655!GO:0045859;regulation of protein kinase activity;0.0223789908677842!GO:0007004;telomere maintenance via telomerase;0.0226490235461924!GO:0005869;dynactin complex;0.0226496239356263!GO:0019318;hexose metabolic process;0.0228025421371266!GO:0016860;intramolecular oxidoreductase activity;0.0228445811404079!GO:0016279;protein-lysine N-methyltransferase activity;0.0246424091389096!GO:0018024;histone-lysine N-methyltransferase activity;0.0246424091389096!GO:0016278;lysine N-methyltransferase activity;0.0246424091389096!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0246850721289361!GO:0015002;heme-copper terminal oxidase activity;0.0246850721289361!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0246850721289361!GO:0004129;cytochrome-c oxidase activity;0.0246850721289361!GO:0005996;monosaccharide metabolic process;0.0248389404186115!GO:0019901;protein kinase binding;0.0257632526869561!GO:0000209;protein polyubiquitination;0.0257632526869561!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0259066135745368!GO:0006007;glucose catabolic process;0.0259605536310666!GO:0005096;GTPase activator activity;0.0260996256549437!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0266047398532492!GO:0005070;SH3/SH2 adaptor activity;0.0267395192956938!GO:0008017;microtubule binding;0.0268253998967125!GO:0031570;DNA integrity checkpoint;0.0269763474729876!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0271281629885786!GO:0005774;vacuolar membrane;0.0277705594382088!GO:0005758;mitochondrial intermembrane space;0.0279104302970961!GO:0046112;nucleobase biosynthetic process;0.0279104302970961!GO:0051090;regulation of transcription factor activity;0.0282317945850234!GO:0030518;steroid hormone receptor signaling pathway;0.0283329453532636!GO:0016301;kinase activity;0.0283329453532636!GO:0042990;regulation of transcription factor import into nucleus;0.0283963736620508!GO:0042991;transcription factor import into nucleus;0.0283963736620508!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.028443590056827!GO:0046966;thyroid hormone receptor binding;0.0286112823746924!GO:0007264;small GTPase mediated signal transduction;0.0288713490748214!GO:0051053;negative regulation of DNA metabolic process;0.0290051536758745!GO:0032984;macromolecular complex disassembly;0.0291791359196397!GO:0009081;branched chain family amino acid metabolic process;0.0292425826215566!GO:0005652;nuclear lamina;0.0292425826215566!GO:0051881;regulation of mitochondrial membrane potential;0.0294474436616822!GO:0031902;late endosome membrane;0.0296366851276176!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0296366851276176!GO:0000726;non-recombinational repair;0.029835442395375!GO:0035267;NuA4 histone acetyltransferase complex;0.0299207009085932!GO:0000178;exosome (RNase complex);0.0300877377141504!GO:0006367;transcription initiation from RNA polymerase II promoter;0.030278727772969!GO:0035035;histone acetyltransferase binding;0.0308509417099224!GO:0003756;protein disulfide isomerase activity;0.0311317898283921!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0311317898283921!GO:0043189;H4/H2A histone acetyltransferase complex;0.0319298723569549!GO:0005784;translocon complex;0.0321337749832782!GO:0003746;translation elongation factor activity;0.0327591927163619!GO:0045815;positive regulation of gene expression, epigenetic;0.032759450078522!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0335800660507477!GO:0051452;cellular pH reduction;0.0342516175370641!GO:0051453;regulation of cellular pH;0.0342516175370641!GO:0045851;pH reduction;0.0342516175370641!GO:0018196;peptidyl-asparagine modification;0.0342516175370641!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0342516175370641!GO:0000792;heterochromatin;0.0343434790868644!GO:0009067;aspartate family amino acid biosynthetic process;0.0349398527661336!GO:0046365;monosaccharide catabolic process;0.0349644351503628!GO:0004659;prenyltransferase activity;0.0349958188872776!GO:0048487;beta-tubulin binding;0.0351388007796629!GO:0000725;recombinational repair;0.0351515477152721!GO:0000724;double-strand break repair via homologous recombination;0.0351515477152721!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0352418439787026!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0352418439787026!GO:0009126;purine nucleoside monophosphate metabolic process;0.0352418439787026!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0352418439787026!GO:0022411;cellular component disassembly;0.0352793212788316!GO:0048468;cell development;0.0356823618470209!GO:0046128;purine ribonucleoside metabolic process;0.0359654141567204!GO:0042278;purine nucleoside metabolic process;0.0359654141567204!GO:0005876;spindle microtubule;0.0363267879934662!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0363621435094799!GO:0006516;glycoprotein catabolic process;0.0365311949165931!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0367866626846575!GO:0051540;metal cluster binding;0.0368962864169663!GO:0051536;iron-sulfur cluster binding;0.0368962864169663!GO:0016569;covalent chromatin modification;0.0369120096555017!GO:0032386;regulation of intracellular transport;0.0371795179562541!GO:0030695;GTPase regulator activity;0.0376801089918967!GO:0030118;clathrin coat;0.0376968704512223!GO:0016407;acetyltransferase activity;0.0387098547726737!GO:0030508;thiol-disulfide exchange intermediate activity;0.0387098547726737!GO:0030027;lamellipodium;0.0387187880229713!GO:0006564;L-serine biosynthetic process;0.0388637279333432!GO:0045892;negative regulation of transcription, DNA-dependent;0.0389770627163789!GO:0005092;GDP-dissociation inhibitor activity;0.0392974652389893!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0395254683138998!GO:0006643;membrane lipid metabolic process;0.0395254683138998!GO:0008408;3'-5' exonuclease activity;0.0403602962681583!GO:0046426;negative regulation of JAK-STAT cascade;0.0404454127056155!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0413553431735749!GO:0006740;NADPH regeneration;0.0415059517300972!GO:0006098;pentose-phosphate shunt;0.0415059517300972!GO:0006406;mRNA export from nucleus;0.0417851065493356!GO:0031647;regulation of protein stability;0.0432442369427594!GO:0008180;signalosome;0.0433439245784187!GO:0008299;isoprenoid biosynthetic process;0.0433519514967161!GO:0032039;integrator complex;0.0439915270236241!GO:0044450;microtubule organizing center part;0.0440100342777497!GO:0042054;histone methyltransferase activity;0.0440832874874075!GO:0006278;RNA-dependent DNA replication;0.0440976253663113!GO:0019900;kinase binding;0.0443506992599344!GO:0008022;protein C-terminus binding;0.0453550631045074!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0455173210646231!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0455173210646231!GO:0004177;aminopeptidase activity;0.0462136181936715!GO:0033116;ER-Golgi intermediate compartment membrane;0.0462224566743762!GO:0050681;androgen receptor binding;0.0462224566743762!GO:0051220;cytoplasmic sequestering of protein;0.0462831065949831!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0467529774295918!GO:0001836;release of cytochrome c from mitochondria;0.0469706518514437!GO:0001726;ruffle;0.0471077121763941!GO:0016605;PML body;0.0474345521651095!GO:0006892;post-Golgi vesicle-mediated transport;0.0477947761279902!GO:0004722;protein serine/threonine phosphatase activity;0.0483465271656885!GO:0044437;vacuolar part;0.0484221420766824!GO:0000080;G1 phase of mitotic cell cycle;0.0484423789546383!GO:0043241;protein complex disassembly;0.0486993133257757!GO:0009396;folic acid and derivative biosynthetic process;0.0490921018756917!GO:0030433;ER-associated protein catabolic process;0.0495572399085406!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0495572399085406 | |||
|sample_id=10828 | |sample_id=10828 | ||
|sample_note= | |sample_note= | ||
| Line 76: | Line 99: | ||
|sample_tissue=blood | |sample_tissue=blood | ||
|top_motifs=TOPORS:1.70207575047;MYB:1.56415497553;ELF1,2,4:1.52475359131;POU3F1..4:1.45147273983;FOXP1:1.37449622822;PITX1..3:1.23642195968;GATA6:1.21396394244;SPI1:1.19394278926;SPIB:1.12727590068;RUNX1..3:1.12157839999;E2F1..5:1.07319909148;HOXA9_MEIS1:1.05646555838;PAX4:1.02377827831;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.0108556332;FOXQ1:1.00580753237;YY1:0.999839417369;ALX1:0.943082028457;DMAP1_NCOR{1,2}_SMARC:0.909755219189;NANOG{mouse}:0.90078010295;POU2F1..3:0.869680010444;TEF:0.865452208616;ETS1,2:0.839643599913;NFY{A,B,C}:0.835800887912;bHLH_family:0.78455784138;HES1:0.758805647424;ONECUT1,2:0.746413285598;TLX2:0.746013257072;PAX8:0.694336711216;NRF1:0.686990235094;ZBTB16:0.672961092853;POU5F1:0.668539579625;HBP1_HMGB_SSRP1_UBTF:0.656575711111;STAT1,3:0.654725142347;FOXD3:0.62996633277;HAND1,2:0.625276524111;IKZF2:0.620638667437;VSX1,2:0.595025987994;HOX{A4,D4}:0.540262463098;ZNF143:0.503099367317;AIRE:0.476698821656;NKX6-1,2:0.469041284385;FOXP3:0.467063101256;DBP:0.446888799193;RREB1:0.424753909726;GCM1,2:0.366570600362;HIF1A:0.359297327414;CUX2:0.355574642286;RFX2..5_RFXANK_RFXAP:0.346875946074;POU1F1:0.342495900004;GZF1:0.321037848267;ARID5B:0.296791223106;TFAP4:0.287900046867;NR5A1,2:0.265807880825;CDX1,2,4:0.254215688332;PAX2:0.240264627372;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.235273726896;SOX{8,9,10}:0.215917196787;PBX1:0.195740951387;FOX{I1,J2}:0.171957890497;FOXN1:0.15762819391;TGIF1:0.14844106984;IRF1,2:0.127853047129;ELK1,4_GABP{A,B1}:0.115445030805;CEBPA,B_DDIT3:0.112009714168;ATF5_CREB3:0.103414096777;AR:0.100810675708;MYOD1:0.0759039325577;RBPJ:0.0742604565098;SOX17:0.0681634099537;MYBL2:0.0554992641416;PAX3,7:0.0380102816402;TFDP1:0.0112230988132;OCT4_SOX2{dimer}:0.00461708410236;SREBF1,2:-0.00983017900034;PDX1:-0.0114359199248;SMAD1..7,9:-0.0402893549634;BREu{core}:-0.0457221222142;ZNF148:-0.0480040224298;FOXA2:-0.0564027370407;PPARG:-0.0586139132319;NFKB1_REL_RELA:-0.0992231006536;FOSL2:-0.117262840299;PAX6:-0.131046660046;HOX{A6,A7,B6,B7}:-0.132638255049;GATA4:-0.134922499672;NR6A1:-0.137825804961;RXR{A,B,G}:-0.146563875254;ZNF423:-0.154052732911;PRRX1,2:-0.167704749309;GFI1:-0.183984252024;SOX5:-0.195474857939;AHR_ARNT_ARNT2:-0.224141959496;ZEB1:-0.226720353625;SNAI1..3:-0.229106557596;HNF4A_NR2F1,2:-0.244385606734;STAT5{A,B}:-0.258897674714;ESR1:-0.266699747611;SPZ1:-0.274599052602;MYFfamily:-0.329465944176;RXRA_VDR{dimer}:-0.330403651062;XBP1:-0.344204668451;NFE2:-0.346336527937;HNF1A:-0.353748017893;ATF4:-0.362054550953;NKX2-3_NKX2-5:-0.374793469173;POU6F1:-0.378656571397;ZNF384:-0.397454719358;TFAP2{A,C}:-0.421674374004;FOS_FOS{B,L1}_JUN{B,D}:-0.433261680869;UFEwm:-0.440054314625;FOXM1:-0.440913956049;BPTF:-0.441095171965;ZNF238:-0.447206471321;SRF:-0.4523229103;HMX1:-0.46063281343;PRDM1:-0.46347690453;SOX2:-0.465077363047;RORA:-0.472113915459;ZBTB6:-0.499339691976;MEF2{A,B,C,D}:-0.513626377323;CRX:-0.541814733029;NKX2-1,4:-0.548609574086;BACH2:-0.550261074987;CDC5L:-0.552368188434;KLF4:-0.560682936391;NFE2L2:-0.56849344497;NKX2-2,8:-0.58486716545;NFATC1..3:-0.58657219951;REST:-0.588385978498;EVI1:-0.606604059346;LMO2:-0.614128848787;MZF1:-0.6187976309;EP300:-0.622178725333;ESRRA:-0.648954159579;GTF2I:-0.663235133327;NKX3-1:-0.68954148161;NFE2L1:-0.690964204098;NKX3-2:-0.729074827411;IRF7:-0.730699169009;HLF:-0.767923383282;PATZ1:-0.77853781471;NHLH1,2:-0.783047158253;HSF1,2:-0.789901434427;NFIL3:-0.791109675655;ZFP161:-0.795029119212;EN1,2:-0.814811437071;LHX3,4:-0.82832524606;FOX{F1,F2,J1}:-0.853432055463;STAT2,4,6:-0.871725742448;HMGA1,2:-0.880684378317;PAX5:-0.882317034722;TFAP2B:-0.92563435084;ATF2:-0.936510915099;ATF6:-0.94019574412;FOX{D1,D2}:-0.96307887133;TEAD1:-0.978564351625;CREB1:-0.980139355594;TBX4,5:-0.995262080856;ZIC1..3:-1.01081099243;PAX1,9:-1.03594371796;NFIX:-1.05701188348;TLX1..3_NFIC{dimer}:-1.05949770783;EBF1:-1.06633982504;MAZ:-1.08059239124;GTF2A1,2:-1.08176042356;SP1:-1.08198064435;LEF1_TCF7_TCF7L1,2:-1.08296400817;MTE{core}:-1.08391173492;MED-1{core}:-1.0912546735;HIC1:-1.11169423528;XCPE1{core}:-1.1248742548;RFX1:-1.13582743113;TBP:-1.13822345069;FOXO1,3,4:-1.14559928705;NANOG:-1.14560517601;TFCP2:-1.25506250402;MTF1:-1.28514558993;MAFB:-1.30628832758;ALX4:-1.3121088723;FOXL1:-1.32639419113;HOX{A5,B5}:-1.33616086242;TP53:-1.41231203864;GFI1B:-1.42546915131;IKZF1:-1.43855965565;EGR1..3:-1.43880124016;NR1H4:-1.45218241929;TAL1_TCF{3,4,12}:-1.45558946129;GLI1..3:-1.66441199835;NR3C1:-1.6801121896;ADNP_IRX_SIX_ZHX:-1.83534929309;JUN:-1.96070076811;T:-2.08160488815 | |top_motifs=TOPORS:1.70207575047;MYB:1.56415497553;ELF1,2,4:1.52475359131;POU3F1..4:1.45147273983;FOXP1:1.37449622822;PITX1..3:1.23642195968;GATA6:1.21396394244;SPI1:1.19394278926;SPIB:1.12727590068;RUNX1..3:1.12157839999;E2F1..5:1.07319909148;HOXA9_MEIS1:1.05646555838;PAX4:1.02377827831;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.0108556332;FOXQ1:1.00580753237;YY1:0.999839417369;ALX1:0.943082028457;DMAP1_NCOR{1,2}_SMARC:0.909755219189;NANOG{mouse}:0.90078010295;POU2F1..3:0.869680010444;TEF:0.865452208616;ETS1,2:0.839643599913;NFY{A,B,C}:0.835800887912;bHLH_family:0.78455784138;HES1:0.758805647424;ONECUT1,2:0.746413285598;TLX2:0.746013257072;PAX8:0.694336711216;NRF1:0.686990235094;ZBTB16:0.672961092853;POU5F1:0.668539579625;HBP1_HMGB_SSRP1_UBTF:0.656575711111;STAT1,3:0.654725142347;FOXD3:0.62996633277;HAND1,2:0.625276524111;IKZF2:0.620638667437;VSX1,2:0.595025987994;HOX{A4,D4}:0.540262463098;ZNF143:0.503099367317;AIRE:0.476698821656;NKX6-1,2:0.469041284385;FOXP3:0.467063101256;DBP:0.446888799193;RREB1:0.424753909726;GCM1,2:0.366570600362;HIF1A:0.359297327414;CUX2:0.355574642286;RFX2..5_RFXANK_RFXAP:0.346875946074;POU1F1:0.342495900004;GZF1:0.321037848267;ARID5B:0.296791223106;TFAP4:0.287900046867;NR5A1,2:0.265807880825;CDX1,2,4:0.254215688332;PAX2:0.240264627372;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.235273726896;SOX{8,9,10}:0.215917196787;PBX1:0.195740951387;FOX{I1,J2}:0.171957890497;FOXN1:0.15762819391;TGIF1:0.14844106984;IRF1,2:0.127853047129;ELK1,4_GABP{A,B1}:0.115445030805;CEBPA,B_DDIT3:0.112009714168;ATF5_CREB3:0.103414096777;AR:0.100810675708;MYOD1:0.0759039325577;RBPJ:0.0742604565098;SOX17:0.0681634099537;MYBL2:0.0554992641416;PAX3,7:0.0380102816402;TFDP1:0.0112230988132;OCT4_SOX2{dimer}:0.00461708410236;SREBF1,2:-0.00983017900034;PDX1:-0.0114359199248;SMAD1..7,9:-0.0402893549634;BREu{core}:-0.0457221222142;ZNF148:-0.0480040224298;FOXA2:-0.0564027370407;PPARG:-0.0586139132319;NFKB1_REL_RELA:-0.0992231006536;FOSL2:-0.117262840299;PAX6:-0.131046660046;HOX{A6,A7,B6,B7}:-0.132638255049;GATA4:-0.134922499672;NR6A1:-0.137825804961;RXR{A,B,G}:-0.146563875254;ZNF423:-0.154052732911;PRRX1,2:-0.167704749309;GFI1:-0.183984252024;SOX5:-0.195474857939;AHR_ARNT_ARNT2:-0.224141959496;ZEB1:-0.226720353625;SNAI1..3:-0.229106557596;HNF4A_NR2F1,2:-0.244385606734;STAT5{A,B}:-0.258897674714;ESR1:-0.266699747611;SPZ1:-0.274599052602;MYFfamily:-0.329465944176;RXRA_VDR{dimer}:-0.330403651062;XBP1:-0.344204668451;NFE2:-0.346336527937;HNF1A:-0.353748017893;ATF4:-0.362054550953;NKX2-3_NKX2-5:-0.374793469173;POU6F1:-0.378656571397;ZNF384:-0.397454719358;TFAP2{A,C}:-0.421674374004;FOS_FOS{B,L1}_JUN{B,D}:-0.433261680869;UFEwm:-0.440054314625;FOXM1:-0.440913956049;BPTF:-0.441095171965;ZNF238:-0.447206471321;SRF:-0.4523229103;HMX1:-0.46063281343;PRDM1:-0.46347690453;SOX2:-0.465077363047;RORA:-0.472113915459;ZBTB6:-0.499339691976;MEF2{A,B,C,D}:-0.513626377323;CRX:-0.541814733029;NKX2-1,4:-0.548609574086;BACH2:-0.550261074987;CDC5L:-0.552368188434;KLF4:-0.560682936391;NFE2L2:-0.56849344497;NKX2-2,8:-0.58486716545;NFATC1..3:-0.58657219951;REST:-0.588385978498;EVI1:-0.606604059346;LMO2:-0.614128848787;MZF1:-0.6187976309;EP300:-0.622178725333;ESRRA:-0.648954159579;GTF2I:-0.663235133327;NKX3-1:-0.68954148161;NFE2L1:-0.690964204098;NKX3-2:-0.729074827411;IRF7:-0.730699169009;HLF:-0.767923383282;PATZ1:-0.77853781471;NHLH1,2:-0.783047158253;HSF1,2:-0.789901434427;NFIL3:-0.791109675655;ZFP161:-0.795029119212;EN1,2:-0.814811437071;LHX3,4:-0.82832524606;FOX{F1,F2,J1}:-0.853432055463;STAT2,4,6:-0.871725742448;HMGA1,2:-0.880684378317;PAX5:-0.882317034722;TFAP2B:-0.92563435084;ATF2:-0.936510915099;ATF6:-0.94019574412;FOX{D1,D2}:-0.96307887133;TEAD1:-0.978564351625;CREB1:-0.980139355594;TBX4,5:-0.995262080856;ZIC1..3:-1.01081099243;PAX1,9:-1.03594371796;NFIX:-1.05701188348;TLX1..3_NFIC{dimer}:-1.05949770783;EBF1:-1.06633982504;MAZ:-1.08059239124;GTF2A1,2:-1.08176042356;SP1:-1.08198064435;LEF1_TCF7_TCF7L1,2:-1.08296400817;MTE{core}:-1.08391173492;MED-1{core}:-1.0912546735;HIC1:-1.11169423528;XCPE1{core}:-1.1248742548;RFX1:-1.13582743113;TBP:-1.13822345069;FOXO1,3,4:-1.14559928705;NANOG:-1.14560517601;TFCP2:-1.25506250402;MTF1:-1.28514558993;MAFB:-1.30628832758;ALX4:-1.3121088723;FOXL1:-1.32639419113;HOX{A5,B5}:-1.33616086242;TP53:-1.41231203864;GFI1B:-1.42546915131;IKZF1:-1.43855965565;EGR1..3:-1.43880124016;NR1H4:-1.45218241929;TAL1_TCF{3,4,12}:-1.45558946129;GLI1..3:-1.66441199835;NR3C1:-1.6801121896;ADNP_IRX_SIX_ZHX:-1.83534929309;JUN:-1.96070076811;T:-2.08160488815 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10828-111C9;search_select_hide=table117:FF:10828-111C9 | |||
}} | }} | ||
Latest revision as of 15:07, 3 June 2020
| Name: | acute myeloid leukemia (FAB M1) cell line:HYT-1 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs13054 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13054
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13054
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.11 |
| 10 | 10 | 0.0252 |
| 100 | 100 | 0.554 |
| 101 | 101 | 0.193 |
| 102 | 102 | 0.433 |
| 103 | 103 | 0.347 |
| 104 | 104 | 0.93 |
| 105 | 105 | 0.854 |
| 106 | 106 | 0.825 |
| 107 | 107 | 0.159 |
| 108 | 108 | 0.856 |
| 109 | 109 | 0.0889 |
| 11 | 11 | 0.171 |
| 110 | 110 | 0.26 |
| 111 | 111 | 0.243 |
| 112 | 112 | 0.827 |
| 113 | 113 | 0.997 |
| 114 | 114 | 0.137 |
| 115 | 115 | 0.907 |
| 116 | 116 | 0.119 |
| 117 | 117 | 0.0144 |
| 118 | 118 | 0.0486 |
| 119 | 119 | 0.673 |
| 12 | 12 | 0.633 |
| 120 | 120 | 0.12 |
| 121 | 121 | 0.862 |
| 122 | 122 | 0.52 |
| 123 | 123 | 2.08652e-5 |
| 124 | 124 | 0.132 |
| 125 | 125 | 0.211 |
| 126 | 126 | 0.271 |
| 127 | 127 | 0.684 |
| 128 | 128 | 0.748 |
| 129 | 129 | 0.933 |
| 13 | 13 | 0.0116 |
| 130 | 130 | 0.755 |
| 131 | 131 | 0.762 |
| 132 | 132 | 0.765 |
| 133 | 133 | 0.906 |
| 134 | 134 | 0.623 |
| 135 | 135 | 0.628 |
| 136 | 136 | 0.237 |
| 137 | 137 | 0.329 |
| 138 | 138 | 0.963 |
| 139 | 139 | 0.307 |
| 14 | 14 | 0.751 |
| 140 | 140 | 0.538 |
| 141 | 141 | 0.294 |
| 142 | 142 | 0.208 |
| 143 | 143 | 0.743 |
| 144 | 144 | 0.321 |
| 145 | 145 | 0.896 |
| 146 | 146 | 0.549 |
| 147 | 147 | 0.106 |
| 148 | 148 | 0.482 |
| 149 | 149 | 0.452 |
| 15 | 15 | 0.567 |
| 150 | 150 | 0.954 |
| 151 | 151 | 0.646 |
| 152 | 152 | 0.623 |
| 153 | 153 | 0.597 |
| 154 | 154 | 0.496 |
| 155 | 155 | 0.0442 |
| 156 | 156 | 0.755 |
| 157 | 157 | 0.139 |
| 158 | 158 | 0.0543 |
| 159 | 159 | 0.107 |
| 16 | 16 | 0.823 |
| 160 | 160 | 0.214 |
| 161 | 161 | 0.0687 |
| 162 | 162 | 0.994 |
| 163 | 163 | 0.499 |
| 164 | 164 | 0.229 |
| 165 | 165 | 0.643 |
| 166 | 166 | 0.556 |
| 167 | 167 | 0.145 |
| 168 | 168 | 0.216 |
| 169 | 169 | 0.0935 |
| 17 | 17 | 0.744 |
| 18 | 18 | 0.604 |
| 19 | 19 | 0.986 |
| 2 | 2 | 0.843 |
| 20 | 20 | 0.704 |
| 21 | 21 | 0.196 |
| 22 | 22 | 0.602 |
| 23 | 23 | 0.151 |
| 24 | 24 | 0.255 |
| 25 | 25 | 0.134 |
| 26 | 26 | 0.214 |
| 27 | 27 | 0.547 |
| 28 | 28 | 0.675 |
| 29 | 29 | 0.0375 |
| 3 | 3 | 0.125 |
| 30 | 30 | 0.0808 |
| 31 | 31 | 0.277 |
| 32 | 32 | 0.0583 |
| 33 | 33 | 0.473 |
| 34 | 34 | 0.962 |
| 35 | 35 | 0.15 |
| 36 | 36 | 0.105 |
| 37 | 37 | 0.123 |
| 38 | 38 | 0.619 |
| 39 | 39 | 0.317 |
| 4 | 4 | 0.226 |
| 40 | 40 | 0.162 |
| 41 | 41 | 0.554 |
| 42 | 42 | 0.403 |
| 43 | 43 | 0.481 |
| 44 | 44 | 0.721 |
| 45 | 45 | 0.778 |
| 46 | 46 | 0.18 |
| 47 | 47 | 0.0676 |
| 48 | 48 | 0.0434 |
| 49 | 49 | 0.214 |
| 5 | 5 | 0.721 |
| 50 | 50 | 0.768 |
| 51 | 51 | 0.588 |
| 52 | 52 | 0.358 |
| 53 | 53 | 0.037 |
| 54 | 54 | 0.848 |
| 55 | 55 | 0.256 |
| 56 | 56 | 0.753 |
| 57 | 57 | 0.144 |
| 58 | 58 | 0.0487 |
| 59 | 59 | 0.525 |
| 6 | 6 | 0.97 |
| 60 | 60 | 0.935 |
| 61 | 61 | 0.0423 |
| 62 | 62 | 0.0544 |
| 63 | 63 | 0.296 |
| 64 | 64 | 0.265 |
| 65 | 65 | 0.83 |
| 66 | 66 | 0.0348 |
| 67 | 67 | 0.849 |
| 68 | 68 | 0.722 |
| 69 | 69 | 0.617 |
| 7 | 7 | 0.04 |
| 70 | 70 | 0.604 |
| 71 | 71 | 0.0234 |
| 72 | 72 | 0.446 |
| 73 | 73 | 0.277 |
| 74 | 74 | 0.346 |
| 75 | 75 | 0.0182 |
| 76 | 76 | 0.617 |
| 77 | 77 | 0.282 |
| 78 | 78 | 0.0208 |
| 79 | 79 | 0.147 |
| 8 | 8 | 0.66 |
| 80 | 80 | 0.155 |
| 81 | 81 | 0.889 |
| 82 | 82 | 0.924 |
| 83 | 83 | 0.214 |
| 84 | 84 | 0.136 |
| 85 | 85 | 0.613 |
| 86 | 86 | 0.461 |
| 87 | 87 | 0.887 |
| 88 | 88 | 0.178 |
| 89 | 89 | 0.52 |
| 9 | 9 | 0.671 |
| 90 | 90 | 0.139 |
| 91 | 91 | 0.325 |
| 92 | 92 | 0.413 |
| 93 | 93 | 0.871 |
| 94 | 94 | 0.763 |
| 95 | 95 | 0.0467 |
| 96 | 96 | 0.526 |
| 97 | 97 | 0.457 |
| 98 | 98 | 0.124 |
| 99 | 99 | 0.466 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13054
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
