FF:10760-110E4: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005899 | ||
|accession_numbers=CAGE;DRX007839;DRR008711;DRZ000136;DRZ001521;DRZ011486;DRZ012871 | |||
|ancestors_in_anatomy_facet= | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000076,CL:0000255 | ||
|ancestors_in_disease_facet=DOID: | |ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:305,DOID:1749 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0102024,FF:0101120 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score=chr17:7493405..7493419,-!p1@SOX15!2.00!100.14!SOX15;;chr11:34642612..34642646,+!p1@EHF!1.80!62.47!EHF;;chr3:189507432..189507459,+!p1@TP63!1.80!62.02!TP63;;chr1:201979743..201979762,+!p1@ELF3!1.73!53.26!ELF3;;chr3:181429704..181429722,+!p1@SOX2!1.73!52.34!SOX2;;chr1:209979467..209979494,-!p1@IRF6!1.66!50.18!IRF6;;chr1:201979703..201979721,+!p2@ELF3!1.66!45.18!ELF3;;chr6:1312325..1312340,+!p1@FOXQ1!1.54!53.82!FOXQ1;;chr8:102504651..102504683,+!p1@GRHL2!1.54!33.91!GRHL2;;chr14:37131058..37131139,+!p1@PAX9!1.50!30.61!PAX9;;chr8:10588010..10588030,-!p1@SOX7!1.41!24.92!SOX7;;chr12:54785074..54785122,-!p2@ZNF385A!1.38!35.28!ZNF385A;;chr9:1050331..1050363,+!p1@DMRT2!1.38!23.10!DMRT2;;chr10:48355030..48355090,+!p1@ZNF488!1.36!28.45!ZNF488;;chr14:38064429..38064486,-!p1@FOXA1!1.36!21.73!FOXA1;;chr3:181429741..181429767,+!p2@SOX2!1.34!20.94!SOX2;;chr12:66218836..66218888,+!p1@HMGA2!1.31!176.27!HMGA2;;chr15:101069113..101069169,-!p1@CERS3!1.30!19.12!CERS3;;chr5:134369905..134369972,-!p1@PITX1!1.25!25.83!PITX1;;chr12:66218255..66218304,+!p3@HMGA2!1.22!41.19!HMGA2;;chr12:54785054..54785072,-!p4@ZNF385A!1.21!17.41!ZNF385A;;chr1:209979411..209979433,-!p2@IRF6!1.20!14.79!IRF6;;chr9:100615499..100615519,+!p1@FOXE1!1.19!14.45!FOXE1;;chr11:120107344..120107351,+!p1@POU2F3!1.17!16.73!POU2F3;;chr13:73633131..73633149,+!p1@KLF5!1.16!143.27!KLF5;;chr5:134369879..134369898,-!p2@PITX1!1.16!13.54!PITX1;;chr17:7492684..7492778,-!p2@SOX15!1.15!27.54!SOX15;;chr12:66218598..66218645,+!p2@HMGA2!1.14!58.60!HMGA2;;chr17:41622765..41622821,-!p2@ETV4!1.14!19.46!ETV4;;chr20:55204351..55204377,+!p1@TFAP2C!1.13!15.93!TFAP2C;;chr5:2751762..2751784,-!p1@IRX2!1.13!12.63!IRX2;;chr6:100061724..100061753,+!p1@PRDM13!1.13!12.40!PRDM13;;chr10:126138597..126138612,-!p1@NKX1-2!1.13!12.40!NKX1-2;;chr10:94449703..94449718,+!p1@HHEX!1.12!47.11!HHEX;;chr9:124976154..124976177,-!p5@LHX6!1.10!11.72!LHX6;;chr3:168864315..168864339,-!p2@MECOM!1.09!18.55!MECOM;;chr3:193853927..193853944,+!p1@HES1!1.08!358.90!HES1;;chr20:42543441..42543497,+!p1@TOX2!1.05!46.77!TOX2;;chr20:42543506..42543549,+!p2@TOX2!1.05!24.81!TOX2;;chr9:124976185..124976212,-!p4@LHX6!1.00!9.10!LHX6;;chr17:41623667..41623682,-!p8@ETV4!0.99!9.44!ETV4;;chr1:6479968..6479986,-!p1@HES2!0.99!8.88!HES2;;chr11:34642656..34642667,+!p2@EHF!0.99!8.76!EHF;;chr17:48072574..48072597,-!p1@DLX3!0.98!8.53!DLX3;;chr17:41623009..41623053,-!p4@ETV4!0.97!13.66!ETV4;;chr3:169381420..169381535,-!p1@MECOM!0.97!9.79!MECOM;;chr17:41622925..41622976,-!p3@ETV4!0.96!12.40!ETV4;;chr9:124991204..124991246,-!p1@LHX6!0.94!7.74!LHX6;;chr17:41623692..41623715,-!p1@ETV4!0.92!32.43!ETV4;;chr12:66218212..66218244,+!p5@HMGA2!0.92!10.92!HMGA2;;chr7:96654026..96654061,-!p2@DLX5!0.92!7.40!DLX5;;chr17:38020392..38020477,-!p1@IKZF3!0.92!7.40!IKZF3;;chr15:96875657..96875760,+!p14@NR2F2!0.90!11.83!NR2F2;;chr15:83953397..83953425,-!p1@BNC1!0.90!7.97!BNC1;;chr8:80680061..80680075,-!p4@HEY1!0.90!6.94!HEY1;;chr12:66218378..66218401,+!p6@HMGA2!0.89!10.70!HMGA2;;chr8:80679993..80680011,-!p1@HEY1!0.88!9.67!HEY1;;chr9:2158443..2158481,+!p2@SMARCA2!0.87!19.23!SMARCA2;;chr20:50721803..50721857,-!p2@ZFP64!0.87!10.47!ZFP64;;chr6:10415276..10415341,-!p2@TFAP2A!0.87!7.97!TFAP2A;;chr12:66218183..66218209,+!p4@HMGA2!0.86!12.40!HMGA2;;chr3:32023232..32023273,+!p1@ZNF860!0.86!9.10!ZNF860;;chr12:66218573..66218596,+!p7@HMGA2!0.84!9.10!HMGA2;;chr8:102504979..102505010,+!p2@GRHL2!0.84!5.92!GRHL2;;chr11:2292226..2292270,-!p1@ASCL2!0.83!5.80!ASCL2;;chr7:96654133..96654150,-!p1@DLX5!0.83!5.69!DLX5;;chr7:27135591..27135658,-!p1@HOXA1!0.82!11.15!HOXA1;;chr12:54332608..54332636,+!p1@HOXC13!0.82!5.58!HOXC13;;chr17:41277372..41277418,-!p1@BRCA1!0.81!21.28!BRCA1;;chr18:19749541..19749557,+!p1@GATA6!0.81!18.21!GATA6;;chr12:48298765..48298783,-!p2@VDR!0.81!11.83!VDR;;chr12:66218443..66218461,+!p8@HMGA2!0.81!7.06!HMGA2;;chr12:125002827..125002855,-!p5@NCOR2!0.79!7.51!NCOR2;;chr3:138665937..138665968,-!p1@FOXL2!0.79!5.23!FOXL2;;chr13:79177703..79177729,-!p2@POU4F1!0.79!5.12!POU4F1;;chr3:12330560..12330579,+!p1@PPARG!0.78!5.92!PPARG;;chr8:80680024..80680046,-!p2@HEY1!0.78!5.80!HEY1;;chr20:30193083..30193098,+!p1@ID1!0.77!434.46!ID1;;chr16:1429627..1429662,-!p2@UNKL!0.77!15.59!UNKL;;chr12:66218152..66218174,+!p10@HMGA2!0.77!5.35!HMGA2;;chr20:42295745..42295765,+!p1@MYBL2!0.75!83.87!MYBL2;;chr15:67430351..67430366,+!p10@SMAD3!0.75!4.67!SMAD3;;chr3:189507460..189507471,+!p3@TP63!0.75!4.67!TP63;;chrX:131623044..131623089,-!p1@MBNL3!0.74!20.71!MBNL3;;chr1:158979851..158979865,+!p5@IFI16!0.74!10.70!IFI16;;chr17:41622834..41622883,-!p6@ETV4!0.74!5.58!ETV4;;chr8:102504690..102504704,+!p3@GRHL2!0.74!4.55!GRHL2;;chr2:238592039..238592054,+!p4@LRRFIP1!0.74!4.44!LRRFIP1;;chr10:135122906..135122921,+!p4@ZNF511!0.74!4.44!ZNF511;;chr6:126102254..126102289,+!p5@NCOA7!0.73!13.31!NCOA7;;chr12:125002861..125002894,-!p7@NCOR2!0.73!6.83!NCOR2;;chr12:66357214..66357233,+!p13@HMGA2!0.72!4.21!HMGA2;;chr17:41622731..41622764,-!p5@ETV4!0.72!4.21!ETV4;;chr10:126138622..126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| |||
|fonse_cell_line=FF:0101120 | |fonse_cell_line=FF:0101120 | ||
|fonse_cell_line_closure=FF:0101120 | |fonse_cell_line_closure=FF:0101120 | ||
Line 35: | Line 40: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/bronchial%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aKNS-62.CNhs11862.10760-110E4.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/bronchial%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aKNS-62.CNhs11862.10760-110E4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/bronchial%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aKNS-62.CNhs11862.10760-110E4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/bronchial%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aKNS-62.CNhs11862.10760-110E4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/bronchial%2520squamous%2520cell%2520carcinoma%2520cell%2520line%253aKNS-62.CNhs11862.10760-110E4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10760-110E4 | |id=FF:10760-110E4 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000210;;FF:0102024 | ||
|is_obsolete= | |||
|library_id=CNhs11862 | |||
|library_id_phase_based=2:CNhs11862 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10760 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10760 | |||
|name=bronchial squamous cell carcinoma cell line:KNS-62 | |name=bronchial squamous cell carcinoma cell line:KNS-62 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
Line 42: | Line 59: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs11862,LSID830,release010,COMPLETED | |profile_hcage=CNhs11862,LSID830,release010,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=110 | |rna_box=110 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
Line 54: | Line 74: | ||
|rna_rin= | |rna_rin= | ||
|rna_sample_type=total RNA | |rna_sample_type=total RNA | ||
|rna_tube_id= | |rna_tube_id=1.10E+06 | ||
|rna_weight_ug=72.70335 | |rna_weight_ug=72.70335 | ||
|sample_age=49 | |sample_age=49 | ||
|sample_category=cell lines | |||
|sample_cell_catalog=ifo50358 | |sample_cell_catalog=ifo50358 | ||
|sample_cell_line=KNS-62 | |sample_cell_line=KNS-62 | ||
Line 69: | Line 90: | ||
|sample_ethnicity=unknown | |sample_ethnicity=unknown | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;5.09031567177915e-250!GO:0005737;cytoplasm;7.82966940261971e-203!GO:0043226;organelle;5.56562938485926e-201!GO:0043229;intracellular organelle;1.42582331936791e-200!GO:0043231;intracellular membrane-bound organelle;5.36621422161349e-195!GO:0043227;membrane-bound organelle;9.77692475910615e-195!GO:0044422;organelle part;9.6490338683159e-166!GO:0044446;intracellular organelle part;2.45062250493526e-164!GO:0044444;cytoplasmic part;2.27285669568899e-146!GO:0032991;macromolecular complex;2.41652166014607e-115!GO:0030529;ribonucleoprotein complex;9.65860779685196e-99!GO:0044237;cellular metabolic process;7.36411971723007e-90!GO:0044238;primary metabolic process;3.23091707306888e-87!GO:0005739;mitochondrion;7.10139422130737e-84!GO:0043233;organelle lumen;4.67811817019088e-82!GO:0031974;membrane-enclosed lumen;4.67811817019088e-82!GO:0044428;nuclear part;1.32917451779271e-80!GO:0003723;RNA binding;2.6225410833515e-79!GO:0043170;macromolecule metabolic process;1.36727969619093e-75!GO:0005634;nucleus;1.15591663077626e-71!GO:0005515;protein binding;1.8364213964126e-66!GO:0005840;ribosome;3.13828776375518e-61!GO:0006396;RNA processing;4.49248945945856e-58!GO:0043234;protein complex;5.07245955689911e-58!GO:0031090;organelle membrane;1.2042199534679e-57!GO:0006412;translation;2.46016333408084e-57!GO:0044429;mitochondrial part;2.77838753587766e-55!GO:0003735;structural constituent of ribosome;9.73221021439167e-53!GO:0009058;biosynthetic process;2.34355081778068e-51!GO:0019538;protein metabolic process;8.58527438986423e-51!GO:0044249;cellular biosynthetic process;2.32432985656822e-49!GO:0031967;organelle envelope;5.68661123077252e-49!GO:0031975;envelope;1.60383078678394e-48!GO:0016043;cellular component organization and biogenesis;5.13612321885676e-48!GO:0031981;nuclear lumen;4.85199528562079e-46!GO:0033279;ribosomal subunit;7.00322515237958e-45!GO:0044267;cellular protein metabolic process;1.59423792811773e-44!GO:0005829;cytosol;1.94596359238081e-44!GO:0009059;macromolecule biosynthetic process;3.07379862624038e-44!GO:0044260;cellular macromolecule metabolic process;6.86459285565131e-44!GO:0015031;protein transport;5.71690907977498e-43!GO:0043228;non-membrane-bound organelle;3.04028745618577e-42!GO:0043232;intracellular non-membrane-bound organelle;3.04028745618577e-42!GO:0016071;mRNA metabolic process;7.99098324633094e-42!GO:0033036;macromolecule localization;8.84188356619502e-42!GO:0043283;biopolymer metabolic process;3.71752660512807e-40!GO:0008104;protein localization;2.79545340748709e-38!GO:0045184;establishment of protein localization;2.85106113906017e-38!GO:0008380;RNA splicing;5.76459665586818e-38!GO:0065003;macromolecular complex assembly;4.57988129369738e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.78016514926391e-36!GO:0006397;mRNA processing;4.22439923177742e-36!GO:0006996;organelle organization and biogenesis;2.11396247902688e-35!GO:0006259;DNA metabolic process;2.73944989712476e-35!GO:0010467;gene expression;1.85253650858969e-34!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.38872298511923e-34!GO:0046907;intracellular transport;4.60965069026133e-34!GO:0022607;cellular component assembly;6.80126415956472e-33!GO:0005740;mitochondrial envelope;1.73940700578061e-32!GO:0006886;intracellular protein transport;3.06667699591903e-31!GO:0031966;mitochondrial membrane;4.85843989450467e-31!GO:0019866;organelle inner membrane;1.67813098342823e-30!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.39066534973808e-30!GO:0005743;mitochondrial inner membrane;6.07687322191925e-28!GO:0000166;nucleotide binding;6.07687322191925e-28!GO:0005681;spliceosome;1.35711654012723e-27!GO:0005654;nucleoplasm;1.87209642388669e-27!GO:0031980;mitochondrial lumen;2.88422038663967e-27!GO:0005759;mitochondrial matrix;2.88422038663967e-27!GO:0007049;cell cycle;3.12989159819395e-26!GO:0012505;endomembrane system;7.81055202689285e-26!GO:0044445;cytosolic part;1.38582446445544e-25!GO:0006119;oxidative phosphorylation;7.20696438901484e-24!GO:0015934;large ribosomal subunit;3.35829361473617e-23!GO:0044455;mitochondrial membrane part;4.27641095860115e-23!GO:0015935;small ribosomal subunit;8.26602984461828e-23!GO:0016462;pyrophosphatase activity;8.27284166342727e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;9.98917837043336e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;1.28665854056418e-22!GO:0051649;establishment of cellular localization;3.15108486654756e-22!GO:0044451;nucleoplasm part;7.29862212256095e-22!GO:0017111;nucleoside-triphosphatase activity;1.02687951147988e-21!GO:0051641;cellular localization;1.87105868775676e-21!GO:0006974;response to DNA damage stimulus;7.20088472859468e-21!GO:0022402;cell cycle process;9.70673927003639e-21!GO:0005730;nucleolus;1.52476043804166e-20!GO:0016874;ligase activity;4.65501579987951e-20!GO:0005761;mitochondrial ribosome;8.78838874007088e-20!GO:0000313;organellar ribosome;8.78838874007088e-20!GO:0022618;protein-RNA complex assembly;1.44096843394448e-19!GO:0044265;cellular macromolecule catabolic process;1.72861164594383e-19!GO:0017076;purine nucleotide binding;1.79477869172157e-19!GO:0032553;ribonucleotide binding;3.20809372522266e-19!GO:0032555;purine ribonucleotide binding;3.20809372522266e-19!GO:0005783;endoplasmic reticulum;6.31086258465831e-19!GO:0043285;biopolymer catabolic process;7.09934819600905e-19!GO:0005694;chromosome;1.15743956071589e-18!GO:0000278;mitotic cell cycle;1.16197862443027e-18!GO:0009057;macromolecule catabolic process;1.49230810056755e-18!GO:0006457;protein folding;2.02413551910389e-18!GO:0051186;cofactor metabolic process;2.2107787531312e-18!GO:0005746;mitochondrial respiratory chain;2.22470705978008e-18!GO:0044248;cellular catabolic process;5.07537698833241e-18!GO:0042254;ribosome biogenesis and assembly;5.47642699608911e-18!GO:0048770;pigment granule;7.26604234718851e-18!GO:0042470;melanosome;7.26604234718851e-18!GO:0005635;nuclear envelope;3.07222258311542e-17!GO:0006281;DNA repair;3.13361201008386e-17!GO:0044427;chromosomal part;3.1477185851735e-17!GO:0030554;adenyl nucleotide binding;3.18937660004224e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;3.25784500048486e-17!GO:0032559;adenyl ribonucleotide binding;3.65976856823998e-17!GO:0008135;translation factor activity, nucleic acid binding;4.22566079917945e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.2634579162185e-17!GO:0005524;ATP binding;4.33434929016339e-17!GO:0019941;modification-dependent protein catabolic process;5.01273282529806e-17!GO:0043632;modification-dependent macromolecule catabolic process;5.01273282529806e-17!GO:0006511;ubiquitin-dependent protein catabolic process;6.49535199866459e-17!GO:0003676;nucleic acid binding;6.68025460265728e-17!GO:0000502;proteasome complex (sensu Eukaryota);7.3579327546152e-17!GO:0044257;cellular protein catabolic process;7.5243520401059e-17!GO:0050136;NADH dehydrogenase (quinone) activity;2.0341178637504e-16!GO:0003954;NADH dehydrogenase activity;2.0341178637504e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.0341178637504e-16!GO:0006605;protein targeting;2.04088791101333e-16!GO:0030163;protein catabolic process;2.14848973035074e-16!GO:0044432;endoplasmic reticulum part;5.26800682513811e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);5.56939640391296e-16!GO:0051276;chromosome organization and biogenesis;7.82533025133631e-16!GO:0009719;response to endogenous stimulus;1.09413523390197e-15!GO:0006512;ubiquitin cycle;1.8322275652194e-15!GO:0006732;coenzyme metabolic process;1.98418591593838e-15!GO:0006260;DNA replication;3.45329931132531e-15!GO:0006399;tRNA metabolic process;4.72412422615294e-15!GO:0031965;nuclear membrane;5.19281497948968e-15!GO:0044453;nuclear membrane part;6.41560256630235e-15!GO:0042775;organelle ATP synthesis coupled electron transport;8.10011479250381e-15!GO:0042773;ATP synthesis coupled electron transport;8.10011479250381e-15!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;8.6863763378409e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;9.77716688735367e-15!GO:0000375;RNA splicing, via transesterification reactions;9.77716688735367e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;9.77716688735367e-15!GO:0022403;cell cycle phase;1.1186866192525e-14!GO:0000087;M phase of mitotic cell cycle;1.6370592851324e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.96007014227592e-14!GO:0030964;NADH dehydrogenase complex (quinone);1.96007014227592e-14!GO:0045271;respiratory chain complex I;1.96007014227592e-14!GO:0005747;mitochondrial respiratory chain complex I;1.96007014227592e-14!GO:0007067;mitosis;3.97583824073945e-14!GO:0016887;ATPase activity;3.98880593820326e-14!GO:0008134;transcription factor binding;4.98875884820259e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;5.0910756922019e-14!GO:0043412;biopolymer modification;6.3371312774195e-14!GO:0005794;Golgi apparatus;7.85935584218792e-14!GO:0051301;cell division;7.97904024602667e-14!GO:0009055;electron carrier activity;1.45705830312948e-13!GO:0005643;nuclear pore;3.52471427481225e-13!GO:0006325;establishment and/or maintenance of chromatin architecture;4.05317878657907e-13!GO:0042623;ATPase activity, coupled;4.64512127099814e-13!GO:0051082;unfolded protein binding;9.58473852896082e-13!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.24737436244638e-12!GO:0000279;M phase;1.32437665059107e-12!GO:0006323;DNA packaging;1.61539768179792e-12!GO:0003743;translation initiation factor activity;1.7310349230152e-12!GO:0006413;translational initiation;2.09001008208338e-12!GO:0005789;endoplasmic reticulum membrane;2.17459750535556e-12!GO:0016070;RNA metabolic process;4.70202344736633e-12!GO:0006364;rRNA processing;7.00253051993232e-12!GO:0048193;Golgi vesicle transport;8.31946768070436e-12!GO:0065002;intracellular protein transport across a membrane;8.71056171550514e-12!GO:0006464;protein modification process;1.44550075038786e-11!GO:0009056;catabolic process;1.54381611517475e-11!GO:0016072;rRNA metabolic process;2.34148556051774e-11!GO:0006461;protein complex assembly;2.72040364634507e-11!GO:0006446;regulation of translational initiation;2.80339279617048e-11!GO:0006913;nucleocytoplasmic transport;4.14701915708597e-11!GO:0051726;regulation of cell cycle;4.29370307186831e-11!GO:0051188;cofactor biosynthetic process;4.71005047966062e-11!GO:0000074;regulation of progression through cell cycle;5.40000235435294e-11!GO:0050657;nucleic acid transport;8.06677323323556e-11!GO:0051236;establishment of RNA localization;8.06677323323556e-11!GO:0050658;RNA transport;8.06677323323556e-11!GO:0006403;RNA localization;9.9959070254604e-11!GO:0004386;helicase activity;1.07654637032815e-10!GO:0051169;nuclear transport;1.07654637032815e-10!GO:0006366;transcription from RNA polymerase II promoter;1.08706756155443e-10!GO:0012501;programmed cell death;1.44596779279408e-10!GO:0016604;nuclear body;1.55382417966566e-10!GO:0008565;protein transporter activity;1.81656933592345e-10!GO:0006915;apoptosis;2.14344951034623e-10!GO:0046930;pore complex;2.1869102643504e-10!GO:0016192;vesicle-mediated transport;2.32438754485774e-10!GO:0000785;chromatin;3.68330224476563e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.10766916779626e-10!GO:0009259;ribonucleotide metabolic process;5.45160130235269e-10!GO:0065004;protein-DNA complex assembly;8.45042374076316e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;8.52154373118421e-10!GO:0004812;aminoacyl-tRNA ligase activity;8.52154373118421e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;8.52154373118421e-10!GO:0016740;transferase activity;1.10858238956973e-09!GO:0006333;chromatin assembly or disassembly;1.29878893324878e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.31457428303798e-09!GO:0009108;coenzyme biosynthetic process;1.49808683349814e-09!GO:0006163;purine nucleotide metabolic process;1.71747732053679e-09!GO:0017038;protein import;1.92330813914435e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.29344734681872e-09!GO:0008026;ATP-dependent helicase activity;2.36031474174072e-09!GO:0043038;amino acid activation;2.5555869627067e-09!GO:0006418;tRNA aminoacylation for protein translation;2.5555869627067e-09!GO:0043039;tRNA aminoacylation;2.5555869627067e-09!GO:0030532;small nuclear ribonucleoprotein complex;3.09179294159912e-09!GO:0043687;post-translational protein modification;3.46522918161079e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;4.02160784270147e-09!GO:0008219;cell death;4.91542463233287e-09!GO:0016265;death;4.91542463233287e-09!GO:0009260;ribonucleotide biosynthetic process;5.08506423012552e-09!GO:0051028;mRNA transport;5.23992628314073e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;5.64650159113297e-09!GO:0006164;purine nucleotide biosynthetic process;5.98130452773418e-09!GO:0009150;purine ribonucleotide metabolic process;1.31022373869022e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.43758428402792e-08!GO:0007005;mitochondrion organization and biogenesis;1.47426384280054e-08!GO:0003712;transcription cofactor activity;1.52789636327226e-08!GO:0016779;nucleotidyltransferase activity;1.60226371417684e-08!GO:0009060;aerobic respiration;1.63326915180892e-08!GO:0043566;structure-specific DNA binding;1.92829028722326e-08!GO:0015986;ATP synthesis coupled proton transport;2.12438269965233e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.12438269965233e-08!GO:0016607;nuclear speck;2.94227327763995e-08!GO:0015078;hydrogen ion transmembrane transporter activity;4.09977670969035e-08!GO:0009152;purine ribonucleotide biosynthetic process;4.62958434796365e-08!GO:0016491;oxidoreductase activity;4.9898653109984e-08!GO:0009141;nucleoside triphosphate metabolic process;5.0381709627634e-08!GO:0016787;hydrolase activity;5.52740735555923e-08!GO:0006261;DNA-dependent DNA replication;5.53124659193809e-08!GO:0051246;regulation of protein metabolic process;8.87641143814987e-08!GO:0019829;cation-transporting ATPase activity;9.19398978099787e-08!GO:0044431;Golgi apparatus part;9.70243808343447e-08!GO:0009117;nucleotide metabolic process;1.08735235086768e-07!GO:0008639;small protein conjugating enzyme activity;1.17147437098649e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.20955552561025e-07!GO:0015630;microtubule cytoskeleton;1.45277441771714e-07!GO:0045333;cellular respiration;1.50406685213961e-07!GO:0006099;tricarboxylic acid cycle;1.60532087296675e-07!GO:0046356;acetyl-CoA catabolic process;1.60532087296675e-07!GO:0003697;single-stranded DNA binding;1.76146273451508e-07!GO:0046034;ATP metabolic process;2.08802627674413e-07!GO:0005768;endosome;2.12689593552391e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.21926582779922e-07!GO:0009144;purine nucleoside triphosphate metabolic process;2.21926582779922e-07!GO:0006334;nucleosome assembly;2.27308241100194e-07!GO:0019787;small conjugating protein ligase activity;2.34952734851214e-07!GO:0009142;nucleoside triphosphate biosynthetic process;2.4752364025304e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.4752364025304e-07!GO:0004842;ubiquitin-protein ligase activity;2.6080014257664e-07!GO:0006084;acetyl-CoA metabolic process;2.77583735421765e-07!GO:0048523;negative regulation of cellular process;2.77722766762523e-07!GO:0048475;coated membrane;2.77816893333854e-07!GO:0030117;membrane coat;2.77816893333854e-07!GO:0006754;ATP biosynthetic process;3.00755951695489e-07!GO:0006753;nucleoside phosphate metabolic process;3.00755951695489e-07!GO:0016881;acid-amino acid ligase activity;3.48889751373062e-07!GO:0045259;proton-transporting ATP synthase complex;3.68285028032282e-07!GO:0005667;transcription factor complex;3.87808986807138e-07!GO:0030120;vesicle coat;4.34132871765188e-07!GO:0030662;coated vesicle membrane;4.34132871765188e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.63963908212956e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.63963908212956e-07!GO:0000314;organellar small ribosomal subunit;5.09542428915424e-07!GO:0005763;mitochondrial small ribosomal subunit;5.09542428915424e-07!GO:0005839;proteasome core complex (sensu Eukaryota);5.50380560075507e-07!GO:0005819;spindle;5.98916311526623e-07!GO:0005762;mitochondrial large ribosomal subunit;6.45438088345189e-07!GO:0000315;organellar large ribosomal subunit;6.45438088345189e-07!GO:0031497;chromatin assembly;7.01033720099036e-07!GO:0005793;ER-Golgi intermediate compartment;7.11019925065967e-07!GO:0043623;cellular protein complex assembly;7.15147041421761e-07!GO:0016469;proton-transporting two-sector ATPase complex;8.2326215491528e-07!GO:0008033;tRNA processing;8.56305658679849e-07!GO:0016568;chromatin modification;9.77806569409486e-07!GO:0000245;spliceosome assembly;1.21705136096848e-06!GO:0042981;regulation of apoptosis;1.67630132089766e-06!GO:0043067;regulation of programmed cell death;1.70599825544497e-06!GO:0051170;nuclear import;1.81366577901332e-06!GO:0003724;RNA helicase activity;2.01536528225059e-06!GO:0004298;threonine endopeptidase activity;2.20648339169414e-06!GO:0008654;phospholipid biosynthetic process;2.23543901703758e-06!GO:0005813;centrosome;2.32359901500813e-06!GO:0000139;Golgi membrane;2.56434272088917e-06!GO:0032446;protein modification by small protein conjugation;2.56670868977012e-06!GO:0005657;replication fork;2.65060287280003e-06!GO:0003899;DNA-directed RNA polymerase activity;2.76728501163786e-06!GO:0009109;coenzyme catabolic process;2.97591951685902e-06!GO:0016567;protein ubiquitination;3.14446019058432e-06!GO:0006752;group transfer coenzyme metabolic process;3.23556451875385e-06!GO:0006888;ER to Golgi vesicle-mediated transport;3.79618194262795e-06!GO:0000775;chromosome, pericentric region;3.83029344699558e-06!GO:0048519;negative regulation of biological process;4.03929972643409e-06!GO:0005815;microtubule organizing center;4.78323885209342e-06!GO:0007051;spindle organization and biogenesis;4.79197792397145e-06!GO:0051187;cofactor catabolic process;5.54698584021264e-06!GO:0006606;protein import into nucleus;6.61616968005766e-06!GO:0042802;identical protein binding;7.18590240936241e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;7.56989604278374e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;8.86598482029263e-06!GO:0031988;membrane-bound vesicle;1.00195843214925e-05!GO:0051329;interphase of mitotic cell cycle;1.04077270266971e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.04597711468526e-05!GO:0016023;cytoplasmic membrane-bound vesicle;1.05542430627969e-05!GO:0006613;cotranslational protein targeting to membrane;1.12570815604895e-05!GO:0000075;cell cycle checkpoint;1.14995867878165e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.3005896333833e-05!GO:0003924;GTPase activity;1.33384878289814e-05!GO:0006626;protein targeting to mitochondrion;1.69875069483071e-05!GO:0006916;anti-apoptosis;2.1880073440135e-05!GO:0006793;phosphorus metabolic process;2.34664179443649e-05!GO:0006796;phosphate metabolic process;2.34664179443649e-05!GO:0006091;generation of precursor metabolites and energy;2.40673897867849e-05!GO:0016853;isomerase activity;2.76838456137695e-05!GO:0016564;transcription repressor activity;2.83263757748465e-05!GO:0019867;outer membrane;3.07482648699655e-05!GO:0044440;endosomal part;3.19350200053711e-05!GO:0010008;endosome membrane;3.19350200053711e-05!GO:0051427;hormone receptor binding;3.38226322852524e-05!GO:0043021;ribonucleoprotein binding;3.69209527871333e-05!GO:0005798;Golgi-associated vesicle;3.76732619175461e-05!GO:0031324;negative regulation of cellular metabolic process;3.96991597298991e-05!GO:0031968;organelle outer membrane;3.9740484182779e-05!GO:0005741;mitochondrial outer membrane;3.98790935425623e-05!GO:0031982;vesicle;3.99773832237819e-05!GO:0051325;interphase;4.16087058273122e-05!GO:0006414;translational elongation;4.1874367396981e-05!GO:0006520;amino acid metabolic process;4.84922319937348e-05!GO:0031410;cytoplasmic vesicle;4.94359260734436e-05!GO:0008094;DNA-dependent ATPase activity;5.33944176288971e-05!GO:0003690;double-stranded DNA binding;6.34228219263055e-05!GO:0044452;nucleolar part;6.74250324692137e-05!GO:0035257;nuclear hormone receptor binding;7.38096721365406e-05!GO:0030867;rough endoplasmic reticulum membrane;7.53276498893528e-05!GO:0005770;late endosome;7.58383913820716e-05!GO:0005788;endoplasmic reticulum lumen;7.59125238720919e-05!GO:0019752;carboxylic acid metabolic process;7.89404590841924e-05!GO:0043681;protein import into mitochondrion;8.52092255357763e-05!GO:0005525;GTP binding;8.56608434525716e-05!GO:0045786;negative regulation of progression through cell cycle;8.75432659387114e-05!GO:0045454;cell redox homeostasis;8.85701230271911e-05!GO:0008186;RNA-dependent ATPase activity;8.98799811298333e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;9.32521589717181e-05!GO:0006082;organic acid metabolic process;9.47875344865102e-05!GO:0048471;perinuclear region of cytoplasm;9.99785213168819e-05!GO:0043069;negative regulation of programmed cell death;0.000103793470770392!GO:0016563;transcription activator activity;0.000103793470770392!GO:0003713;transcription coactivator activity;0.000110633050177273!GO:0005773;vacuole;0.00011246978551204!GO:0000151;ubiquitin ligase complex;0.000120019056661134!GO:0046467;membrane lipid biosynthetic process;0.000126002244498513!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000126875841041857!GO:0009892;negative regulation of metabolic process;0.000127915970657638!GO:0016310;phosphorylation;0.000143177538835492!GO:0051168;nuclear export;0.000144234173843959!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000144616161775164!GO:0050662;coenzyme binding;0.000163625488319885!GO:0043066;negative regulation of apoptosis;0.000203301115102018!GO:0006302;double-strand break repair;0.000217233907765678!GO:0006839;mitochondrial transport;0.000217570768010614!GO:0016859;cis-trans isomerase activity;0.000236085086889129!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000248759167992573!GO:0000786;nucleosome;0.000259947623008653!GO:0000323;lytic vacuole;0.000259947623008653!GO:0005764;lysosome;0.000259947623008653!GO:0004004;ATP-dependent RNA helicase activity;0.000259947623008653!GO:0004576;oligosaccharyl transferase activity;0.000272746994477016!GO:0006612;protein targeting to membrane;0.00028740156012722!GO:0007006;mitochondrial membrane organization and biogenesis;0.000303773962988374!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000305887471274735!GO:0030880;RNA polymerase complex;0.000311078221671573!GO:0003682;chromatin binding;0.000318159039318008!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000350777744924018!GO:0005769;early endosome;0.000352762347420704!GO:0008250;oligosaccharyl transferase complex;0.000365088723388454!GO:0006402;mRNA catabolic process;0.000399809788051063!GO:0000059;protein import into nucleus, docking;0.000408084098087402!GO:0009165;nucleotide biosynthetic process;0.000419749497940261!GO:0000049;tRNA binding;0.000431124790556758!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000431517343718774!GO:0015399;primary active transmembrane transporter activity;0.000431517343718774!GO:0030118;clathrin coat;0.000435881394461802!GO:0051052;regulation of DNA metabolic process;0.000466937438704465!GO:0048522;positive regulation of cellular process;0.000477014574265086!GO:0030119;AP-type membrane coat adaptor complex;0.000514865799789741!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000527080178329324!GO:0005048;signal sequence binding;0.000588214150170477!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000622418987387444!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000624757738719223!GO:0008652;amino acid biosynthetic process;0.000629131494550002!GO:0000776;kinetochore;0.000641900032369035!GO:0030131;clathrin adaptor complex;0.000648397212381445!GO:0030176;integral to endoplasmic reticulum membrane;0.00071185603604601!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00071185603604601!GO:0046483;heterocycle metabolic process;0.00071185603604601!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000714196326795806!GO:0000428;DNA-directed RNA polymerase complex;0.000714196326795806!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000749546372036621!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000749546372036621!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000749546372036621!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000761020345293306!GO:0032561;guanyl ribonucleotide binding;0.000772301048288638!GO:0019001;guanyl nucleotide binding;0.000772301048288638!GO:0003729;mRNA binding;0.000777587747474222!GO:0051920;peroxiredoxin activity;0.000781190798724543!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000781190798724543!GO:0007088;regulation of mitosis;0.000781402934148002!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000802625353668281!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000802625353668281!GO:0016481;negative regulation of transcription;0.000802625353668281!GO:0009451;RNA modification;0.000871572540086364!GO:0006401;RNA catabolic process;0.000878494081010816!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000928551907358432!GO:0019899;enzyme binding;0.000950853807578287!GO:0046474;glycerophospholipid biosynthetic process;0.000976236246809562!GO:0048037;cofactor binding;0.00100174627788367!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00102071762836747!GO:0005684;U2-dependent spliceosome;0.00107026408200866!GO:0046489;phosphoinositide biosynthetic process;0.00107505337385677!GO:0006519;amino acid and derivative metabolic process;0.0010844572155909!GO:0005885;Arp2/3 protein complex;0.0011388705557903!GO:0003746;translation elongation factor activity;0.0011388705557903!GO:0016741;transferase activity, transferring one-carbon groups;0.00123424210490976!GO:0032984;macromolecular complex disassembly;0.00126076829774206!GO:0048500;signal recognition particle;0.00126159022702719!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00128273859428278!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00128510283869588!GO:0008168;methyltransferase activity;0.0013083287492424!GO:0005637;nuclear inner membrane;0.00130944974905509!GO:0007052;mitotic spindle organization and biogenesis;0.00146035436449693!GO:0007093;mitotic cell cycle checkpoint;0.00147927850230293!GO:0033116;ER-Golgi intermediate compartment membrane;0.00153697793174727!GO:0003714;transcription corepressor activity;0.00163828242319848!GO:0018196;peptidyl-asparagine modification;0.00163828242319848!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00163828242319848!GO:0050794;regulation of cellular process;0.00172359359943355!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00174239764278916!GO:0009112;nucleobase metabolic process;0.0017509190502541!GO:0016251;general RNA polymerase II transcription factor activity;0.00175288654025689!GO:0005905;coated pit;0.00177404586386464!GO:0019843;rRNA binding;0.00184613254634871!GO:0043488;regulation of mRNA stability;0.00184613254634871!GO:0043487;regulation of RNA stability;0.00184613254634871!GO:0008610;lipid biosynthetic process;0.00185851529313277!GO:0031252;leading edge;0.001911189012455!GO:0015631;tubulin binding;0.00203654884554039!GO:0007010;cytoskeleton organization and biogenesis;0.00208030106437457!GO:0043241;protein complex disassembly;0.00214490193556569!GO:0051252;regulation of RNA metabolic process;0.00218389306344096!GO:0008312;7S RNA binding;0.00220046340181214!GO:0016044;membrane organization and biogenesis;0.00223296633359416!GO:0016363;nuclear matrix;0.00224201430605513!GO:0006672;ceramide metabolic process;0.00230532153351047!GO:0030132;clathrin coat of coated pit;0.00237305085488423!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00237305085488423!GO:0003684;damaged DNA binding;0.00241237741272943!GO:0030663;COPI coated vesicle membrane;0.00245964298423324!GO:0030126;COPI vesicle coat;0.00245964298423324!GO:0006818;hydrogen transport;0.00246705770321058!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0024976932844871!GO:0015992;proton transport;0.00254454150144409!GO:0043624;cellular protein complex disassembly;0.00254454150144409!GO:0006352;transcription initiation;0.00273834083931224!GO:0015980;energy derivation by oxidation of organic compounds;0.00287456297438601!GO:0000082;G1/S transition of mitotic cell cycle;0.00291036528904985!GO:0065009;regulation of a molecular function;0.00294001645373275!GO:0032508;DNA duplex unwinding;0.00294001645373275!GO:0032392;DNA geometric change;0.00294001645373275!GO:0006383;transcription from RNA polymerase III promoter;0.00314644639069997!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00320201910054691!GO:0045047;protein targeting to ER;0.00320201910054691!GO:0006310;DNA recombination;0.00343322833625256!GO:0005791;rough endoplasmic reticulum;0.00352358575127417!GO:0003702;RNA polymerase II transcription factor activity;0.00373086816926516!GO:0031072;heat shock protein binding;0.00382021618126229!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00390831746823616!GO:0004527;exonuclease activity;0.00392233374812937!GO:0045941;positive regulation of transcription;0.0039382035713248!GO:0006405;RNA export from nucleus;0.0039676773774588!GO:0006118;electron transport;0.00415093602900097!GO:0008629;induction of apoptosis by intracellular signals;0.00417797658052132!GO:0051789;response to protein stimulus;0.00440786780705794!GO:0006986;response to unfolded protein;0.00440786780705794!GO:0046519;sphingoid metabolic process;0.00441439414244079!GO:0043492;ATPase activity, coupled to movement of substances;0.00441721798075405!GO:0006400;tRNA modification;0.00445269941672072!GO:0045893;positive regulation of transcription, DNA-dependent;0.00466668343019507!GO:0016272;prefoldin complex;0.00471683570676489!GO:0030036;actin cytoskeleton organization and biogenesis;0.00471962422875219!GO:0030658;transport vesicle membrane;0.00472307958854554!GO:0006144;purine base metabolic process;0.00478019935671417!GO:0031970;organelle envelope lumen;0.00489910889014982!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0049102105530446!GO:0030137;COPI-coated vesicle;0.00499747179200258!GO:0000096;sulfur amino acid metabolic process;0.00502770587973655!GO:0009081;branched chain family amino acid metabolic process;0.00503626363242414!GO:0006733;oxidoreduction coenzyme metabolic process;0.00507739183868043!GO:0005876;spindle microtubule;0.00520185716955715!GO:0043596;nuclear replication fork;0.0052334989838506!GO:0006643;membrane lipid metabolic process;0.00533236802368999!GO:0035258;steroid hormone receptor binding;0.00550909519496261!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00556522658982799!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00570218638024239!GO:0007017;microtubule-based process;0.00570218638024239!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00570218638024239!GO:0043022;ribosome binding;0.00573628571025655!GO:0006275;regulation of DNA replication;0.00581312888488782!GO:0009116;nucleoside metabolic process;0.00583081991050226!GO:0000922;spindle pole;0.0058791147706894!GO:0008139;nuclear localization sequence binding;0.00601099204418041!GO:0005874;microtubule;0.0061176438284761!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00626415172961733!GO:0003678;DNA helicase activity;0.00626415172961733!GO:0006268;DNA unwinding during replication;0.00636713709975177!GO:0004518;nuclease activity;0.00649087796054908!GO:0007059;chromosome segregation;0.00660314419663297!GO:0006611;protein export from nucleus;0.00667478104929818!GO:0005853;eukaryotic translation elongation factor 1 complex;0.00680711289541309!GO:0006506;GPI anchor biosynthetic process;0.00707816367114717!GO:0022411;cellular component disassembly;0.00707816367114717!GO:0042770;DNA damage response, signal transduction;0.00707816367114717!GO:0006007;glucose catabolic process;0.0070817916382627!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.007184630659014!GO:0015002;heme-copper terminal oxidase activity;0.007184630659014!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.007184630659014!GO:0004129;cytochrome-c oxidase activity;0.007184630659014!GO:0006497;protein amino acid lipidation;0.00733045480045531!GO:0031301;integral to organelle membrane;0.0079844643782281!GO:0031124;mRNA 3'-end processing;0.00799015730527934!GO:0030133;transport vesicle;0.00807391522042537!GO:0016126;sterol biosynthetic process;0.00829350932878343!GO:0008022;protein C-terminus binding;0.00840624619917484!GO:0000339;RNA cap binding;0.00843378353500093!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00847720788968563!GO:0046983;protein dimerization activity;0.00867376082824969!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00869860704733828!GO:0006595;polyamine metabolic process;0.00873706346488324!GO:0003711;transcription elongation regulator activity;0.00882059832942057!GO:0051287;NAD binding;0.00884795281234298!GO:0045045;secretory pathway;0.00884795281234298!GO:0006505;GPI anchor metabolic process;0.00885240988127451!GO:0006284;base-excision repair;0.00914512095235966!GO:0051087;chaperone binding;0.00923370800530156!GO:0030660;Golgi-associated vesicle membrane;0.00936348543525088!GO:0043284;biopolymer biosynthetic process;0.00939597844950247!GO:0007040;lysosome organization and biogenesis;0.00952396622054885!GO:0043189;H4/H2A histone acetyltransferase complex;0.00958863873311838!GO:0004674;protein serine/threonine kinase activity;0.00979697907996581!GO:0030125;clathrin vesicle coat;0.00979697907996581!GO:0030665;clathrin coated vesicle membrane;0.00979697907996581!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00986892490653467!GO:0051539;4 iron, 4 sulfur cluster binding;0.00986892490653467!GO:0008632;apoptotic program;0.00992802325900557!GO:0007264;small GTPase mediated signal transduction;0.00992982358586474!GO:0048487;beta-tubulin binding;0.00994733435281214!GO:0006378;mRNA polyadenylation;0.0104685963213139!GO:0008180;signalosome;0.0107564403459736!GO:0005758;mitochondrial intermembrane space;0.0109148382359665!GO:0046982;protein heterodimerization activity;0.0111320629811592!GO:0005832;chaperonin-containing T-complex;0.0111572229170631!GO:0000287;magnesium ion binding;0.0113155926275507!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0114694519895212!GO:0051540;metal cluster binding;0.0116231329176602!GO:0051536;iron-sulfur cluster binding;0.0116231329176602!GO:0006289;nucleotide-excision repair;0.0116974401235474!GO:0006950;response to stress;0.0118123041431613!GO:0031529;ruffle organization and biogenesis;0.01214778654914!GO:0006891;intra-Golgi vesicle-mediated transport;0.0126305335243047!GO:0000178;exosome (RNase complex);0.0128586830732342!GO:0006892;post-Golgi vesicle-mediated transport;0.0130726531481803!GO:0006740;NADPH regeneration;0.0130726531481803!GO:0006098;pentose-phosphate shunt;0.0130726531481803!GO:0022890;inorganic cation transmembrane transporter activity;0.0135147499288554!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0144832657501695!GO:0000725;recombinational repair;0.0148049870740951!GO:0000724;double-strand break repair via homologous recombination;0.0148049870740951!GO:0008408;3'-5' exonuclease activity;0.0148472804404424!GO:0016791;phosphoric monoester hydrolase activity;0.0148751168840846!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0149673772784423!GO:0005663;DNA replication factor C complex;0.0155973301894035!GO:0006749;glutathione metabolic process;0.0160214906786116!GO:0050178;phenylpyruvate tautomerase activity;0.0162489611229107!GO:0004532;exoribonuclease activity;0.0163291626104626!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0163291626104626!GO:0006417;regulation of translation;0.0165065026185172!GO:0030659;cytoplasmic vesicle membrane;0.0171396047134201!GO:0006807;nitrogen compound metabolic process;0.0173691525329091!GO:0035267;NuA4 histone acetyltransferase complex;0.0174166407617634!GO:0006730;one-carbon compound metabolic process;0.0175351307132409!GO:0000792;heterochromatin;0.0178028101360463!GO:0006650;glycerophospholipid metabolic process;0.0186693488120872!GO:0009308;amine metabolic process;0.0187299313412059!GO:0000123;histone acetyltransferase complex;0.0188942959236074!GO:0008538;proteasome activator activity;0.0190512376934403!GO:0051338;regulation of transferase activity;0.0191541201384847!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0194284334207265!GO:0046112;nucleobase biosynthetic process;0.0195575432507004!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0198072023569064!GO:0045039;protein import into mitochondrial inner membrane;0.0198072023569064!GO:0016584;nucleosome positioning;0.0199577976459244!GO:0017166;vinculin binding;0.0200817529890017!GO:0048518;positive regulation of biological process;0.0201270771517153!GO:0001889;liver development;0.0206186577481828!GO:0005669;transcription factor TFIID complex;0.0207939923100284!GO:0007033;vacuole organization and biogenesis;0.0208818166812051!GO:0006979;response to oxidative stress;0.0217751331963745!GO:0044433;cytoplasmic vesicle part;0.0219008142096635!GO:0045892;negative regulation of transcription, DNA-dependent;0.0219008142096635!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.0220442090378454!GO:0006767;water-soluble vitamin metabolic process;0.0220614459779807!GO:0009083;branched chain family amino acid catabolic process;0.0220861862564959!GO:0043433;negative regulation of transcription factor activity;0.0220990945858434!GO:0006270;DNA replication initiation;0.0223694616829741!GO:0001558;regulation of cell growth;0.0224366205707306!GO:0007050;cell cycle arrest;0.0224722562241139!GO:0009124;nucleoside monophosphate biosynthetic process;0.0225415048412452!GO:0009123;nucleoside monophosphate metabolic process;0.0225415048412452!GO:0008361;regulation of cell size;0.0227403693681212!GO:0006338;chromatin remodeling;0.0228790864930381!GO:0042158;lipoprotein biosynthetic process;0.0230212098786701!GO:0030384;phosphoinositide metabolic process;0.023484261064122!GO:0006509;membrane protein ectodomain proteolysis;0.0234883792980938!GO:0033619;membrane protein proteolysis;0.0234883792980938!GO:0031371;ubiquitin conjugating enzyme complex;0.0237249280411716!GO:0046966;thyroid hormone receptor binding;0.0240449224362132!GO:0000228;nuclear chromosome;0.0242652192444935!GO:0006607;NLS-bearing substrate import into nucleus;0.0243523968545957!GO:0030503;regulation of cell redox homeostasis;0.0245389957254728!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0246256991392922!GO:0030029;actin filament-based process;0.0247559976266673!GO:0033673;negative regulation of kinase activity;0.0248024331182374!GO:0006469;negative regulation of protein kinase activity;0.0248024331182374!GO:0008017;microtubule binding;0.0250275980317783!GO:0043601;nuclear replisome;0.0251282095154599!GO:0030894;replisome;0.0251282095154599!GO:0046365;monosaccharide catabolic process;0.0251291325405442!GO:0032200;telomere organization and biogenesis;0.0251580947679743!GO:0000723;telomere maintenance;0.0251580947679743!GO:0016835;carbon-oxygen lyase activity;0.0252870168524581!GO:0031123;RNA 3'-end processing;0.0254247783217475!GO:0016653;oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor;0.0259374744438589!GO:0046822;regulation of nucleocytoplasmic transport;0.0259749346332883!GO:0051101;regulation of DNA binding;0.0261063254463311!GO:0051348;negative regulation of transferase activity;0.0266736452368243!GO:0006984;ER-nuclear signaling pathway;0.0269189408437156!GO:0019783;small conjugating protein-specific protease activity;0.026955581685413!GO:0012506;vesicle membrane;0.0272135726901926!GO:0006376;mRNA splice site selection;0.0272135726901926!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0272135726901926!GO:0043130;ubiquitin binding;0.027523360497879!GO:0032182;small conjugating protein binding;0.027523360497879!GO:0008234;cysteine-type peptidase activity;0.027564381498942!GO:0016197;endosome transport;0.0282036312499944!GO:0001726;ruffle;0.028516785938654!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0285306527601304!GO:0051098;regulation of binding;0.0286855883544917!GO:0016790;thiolester hydrolase activity;0.0286855883544917!GO:0009161;ribonucleoside monophosphate metabolic process;0.0287366697189865!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0287366697189865!GO:0009166;nucleotide catabolic process;0.02926950349992!GO:0046128;purine ribonucleoside metabolic process;0.0295933921745506!GO:0042278;purine nucleoside metabolic process;0.0295933921745506!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0306835926697966!GO:0031570;DNA integrity checkpoint;0.0307908612252326!GO:0043065;positive regulation of apoptosis;0.0313921965855295!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0318743642378614!GO:0030911;TPR domain binding;0.0323689761448973!GO:0003923;GPI-anchor transamidase activity;0.0323689761448973!GO:0016255;attachment of GPI anchor to protein;0.0323689761448973!GO:0042765;GPI-anchor transamidase complex;0.0323689761448973!GO:0009303;rRNA transcription;0.0323689761448973!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0325424437406842!GO:0001522;pseudouridine synthesis;0.0328387576106806!GO:0006360;transcription from RNA polymerase I promoter;0.0329581315419791!GO:0030134;ER to Golgi transport vesicle;0.0331047359934887!GO:0030521;androgen receptor signaling pathway;0.0332437071845245!GO:0022415;viral reproductive process;0.0332437872282885!GO:0000086;G2/M transition of mitotic cell cycle;0.0332437872282885!GO:0006541;glutamine metabolic process;0.03367688606507!GO:0006739;NADP metabolic process;0.0338112382101559!GO:0046164;alcohol catabolic process;0.0339681411324597!GO:0019206;nucleoside kinase activity;0.0342900261027507!GO:0005784;translocon complex;0.0344450345171881!GO:0007243;protein kinase cascade;0.0344470855220546!GO:0045947;negative regulation of translational initiation;0.0344892248858013!GO:0016049;cell growth;0.0345277583148546!GO:0044262;cellular carbohydrate metabolic process;0.0349348564114438!GO:0030140;trans-Golgi network transport vesicle;0.0353452225287546!GO:0045334;clathrin-coated endocytic vesicle;0.0354408665086639!GO:0004128;cytochrome-b5 reductase activity;0.0358250133095373!GO:0004843;ubiquitin-specific protease activity;0.0358348537635073!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0363397553949888!GO:0051053;negative regulation of DNA metabolic process;0.0364285417120735!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0370939283283927!GO:0010257;NADH dehydrogenase complex assembly;0.0370939283283927!GO:0033108;mitochondrial respiratory chain complex assembly;0.0370939283283927!GO:0030127;COPII vesicle coat;0.0372747424034086!GO:0012507;ER to Golgi transport vesicle membrane;0.0372747424034086!GO:0017134;fibroblast growth factor binding;0.037716241652387!GO:0032259;methylation;0.037924502205206!GO:0005774;vacuolar membrane;0.0382885829527845!GO:0043549;regulation of kinase activity;0.0384224688516529!GO:0044454;nuclear chromosome part;0.0384642072516806!GO:0046554;malate dehydrogenase (NADP+) activity;0.0384737710798447!GO:0050790;regulation of catalytic activity;0.0386034191671294!GO:0019320;hexose catabolic process;0.0388186857993654!GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors;0.0398618285519126!GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;0.0399221772862158!GO:0042769;DNA damage response, detection of DNA damage;0.0400465713022801!GO:0043414;biopolymer methylation;0.0401943478577001!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0402175801430292!GO:0043068;positive regulation of programmed cell death;0.0403347565111507!GO:0007021;tubulin folding;0.0403347565111507!GO:0009067;aspartate family amino acid biosynthetic process;0.040382608356208!GO:0005732;small nucleolar ribonucleoprotein complex;0.0415125290976908!GO:0006665;sphingolipid metabolic process;0.041844952110802!GO:0004239;methionyl aminopeptidase activity;0.0425038469436778!GO:0051128;regulation of cellular component organization and biogenesis;0.0434088527516654!GO:0044450;microtubule organizing center part;0.0437073975830041!GO:0008426;protein kinase C inhibitor activity;0.0439052462978752!GO:0004721;phosphoprotein phosphatase activity;0.0440820460121181!GO:0006354;RNA elongation;0.0449198859197879!GO:0040029;regulation of gene expression, epigenetic;0.0450112349906889!GO:0004221;ubiquitin thiolesterase activity;0.0452503860410985!GO:0000726;non-recombinational repair;0.0453273950578838!GO:0004003;ATP-dependent DNA helicase activity;0.0466990804550335!GO:0030145;manganese ion binding;0.0467885728695654!GO:0007004;telomere maintenance via telomerase;0.046919433835325!GO:0016836;hydro-lyase activity;0.0477155986049324!GO:0031326;regulation of cellular biosynthetic process;0.0477155986049324!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0478793165202843!GO:0003756;protein disulfide isomerase activity;0.0479507537253462!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0479507537253462!GO:0033170;DNA-protein loading ATPase activity;0.0479507537253462!GO:0003689;DNA clamp loader activity;0.0479507537253462!GO:0042393;histone binding;0.0486160763913869!GO:0048468;cell development;0.0486174352444716!GO:0048146;positive regulation of fibroblast proliferation;0.0488834429676872!GO:0030508;thiol-disulfide exchange intermediate activity;0.0491324451946468!GO:0004300;enoyl-CoA hydratase activity;0.0491324451946468!GO:0005869;dynactin complex;0.0494252978798873!GO:0009893;positive regulation of metabolic process;0.049822937503074!GO:0006096;glycolysis;0.0499915721436026!GO:0030128;clathrin coat of endocytic vesicle;0.0499915721436026!GO:0030669;clathrin-coated endocytic vesicle membrane;0.0499915721436026!GO:0030122;AP-2 adaptor complex;0.0499915721436026 | |||
|sample_id=10760 | |sample_id=10760 | ||
|sample_note= | |sample_note= | ||
Line 76: | Line 98: | ||
|sample_tissue=lung | |sample_tissue=lung | ||
|top_motifs=SNAI1..3:1.88282920452;ZEB1:1.8186761173;bHLH_family:1.68369081768;VSX1,2:1.63451070309;ALX1:1.40382167113;POU1F1:1.40302025732;TOPORS:1.38609584829;FOX{I1,J2}:1.38222391572;NR6A1:1.05790632359;TP53:1.04851480616;HIF1A:1.03593929285;FOXQ1:1.00297776595;POU2F1..3:0.989752039561;CDX1,2,4:0.976851151039;ZBTB16:0.964808833949;MYOD1:0.959229680968;ZNF423:0.942321142761;NKX2-3_NKX2-5:0.882937599353;E2F1..5:0.845087360841;PITX1..3:0.840553102489;TFDP1:0.807462876523;LHX3,4:0.807119937032;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.782579984596;ELK1,4_GABP{A,B1}:0.766220618443;ONECUT1,2:0.752008018109;CDC5L:0.733394714459;FOXD3:0.713585692959;STAT5{A,B}:0.692771240882;YY1:0.672457639595;ADNP_IRX_SIX_ZHX:0.617012159027;TEF:0.602809786465;FOXM1:0.551478333654;PDX1:0.540846540809;FOXP1:0.504284098245;ZNF384:0.488850477838;BREu{core}:0.478246711332;NKX2-1,4:0.40901028;LMO2:0.392543884542;NFIL3:0.373265941303;AIRE:0.359264530454;HSF1,2:0.340624877353;HIC1:0.331764543981;NANOG:0.330682424554;IKZF1:0.323277618763;POU6F1:0.319064691198;NKX2-2,8:0.316645260663;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.296792835232;ARID5B:0.292911943435;HOX{A4,D4}:0.291481702967;PAX8:0.285186134152;NKX6-1,2:0.279428566766;NFY{A,B,C}:0.269588550203;RBPJ:0.262358455633;OCT4_SOX2{dimer}:0.201669814185;ZNF143:0.193827198726;TEAD1:0.181093025837;NKX3-2:0.171430808647;TBX4,5:0.168237373025;XCPE1{core}:0.161566626438;PAX1,9:0.15550959099;HAND1,2:0.142715167906;TFAP2{A,C}:0.139333994636;SP1:0.13064190287;HOX{A6,A7,B6,B7}:0.125697361122;PRRX1,2:0.122105187324;KLF4:0.118671849289;PBX1:0.110094706888;PAX4:0.104294184805;REST:0.0876412488953;IKZF2:0.0584420709035;ELF1,2,4:0.0413208932213;TLX1..3_NFIC{dimer}:0.0348957575286;UFEwm:0.034397183206;MTF1:0.0272912914842;NRF1:0.0174066132188;NFE2:0.000210423622018;RFX1:-0.00145572982237;FOSL2:-0.0104241026489;TFAP2B:-0.0146020939541;IRF7:-0.0173871331666;FOS_FOS{B,L1}_JUN{B,D}:-0.0188729172906;MYB:-0.0212869138888;PAX2:-0.0399314403037;PPARG:-0.0411967602997;HOX{A5,B5}:-0.0480805432103;GCM1,2:-0.0769135024015;ZNF148:-0.0847834550695;SOX17:-0.085391850278;ZBTB6:-0.090876645694;SOX{8,9,10}:-0.0931653578463;GTF2A1,2:-0.0948932218876;MED-1{core}:-0.106414207362;NR5A1,2:-0.10824538219;SOX2:-0.133763275109;BACH2:-0.139733017675;POU5F1:-0.140339881708;HNF4A_NR2F1,2:-0.157985352708;FOXL1:-0.176075148881;FOXA2:-0.189724684348;PAX6:-0.190288765124;PAX3,7:-0.200344777953;HNF1A:-0.202054609443;LEF1_TCF7_TCF7L1,2:-0.202694585766;PRDM1:-0.222286113916;ZIC1..3:-0.233581439381;TBP:-0.25520349783;MTE{core}:-0.258736035202;ESR1:-0.274192261584;GFI1:-0.274882258869;RORA:-0.290838384644;ATF4:-0.302723254665;FOXO1,3,4:-0.310384529602;FOXN1:-0.311855654307;EVI1:-0.323191766633;MYBL2:-0.329200154337;SREBF1,2:-0.330402758313;FOX{F1,F2,J1}:-0.333159724467;NFE2L2:-0.340868916129;AHR_ARNT_ARNT2:-0.348356923496;CEBPA,B_DDIT3:-0.361287929028;NFKB1_REL_RELA:-0.364328271159;CRX:-0.365252693199;RFX2..5_RFXANK_RFXAP:-0.371137421231;CUX2:-0.40018187059;NKX3-1:-0.403599643636;HES1:-0.405099693491;EN1,2:-0.408474738785;HMGA1,2:-0.416506113569;EGR1..3:-0.419654907779;PAX5:-0.428748239213;GATA6:-0.433165709119;RXR{A,B,G}:-0.458577894503;GATA4:-0.481034082798;DMAP1_NCOR{1,2}_SMARC:-0.505594875832;HLF:-0.514015830911;ATF5_CREB3:-0.521289561896;GTF2I:-0.535316543137;SPIB:-0.546168566995;GLI1..3:-0.557469327019;ETS1,2:-0.564770636992;ZFP161:-0.567376666209;PATZ1:-0.588536467471;SPI1:-0.591832336723;EBF1:-0.598825807375;HOXA9_MEIS1:-0.599014764908;TFCP2:-0.607431736157;T:-0.613073057289;RREB1:-0.615365777788;CREB1:-0.623985554988;ALX4:-0.628082091016;NR1H4:-0.62822875457;MEF2{A,B,C,D}:-0.639093211388;EP300:-0.649502614265;POU3F1..4:-0.660973266543;MAZ:-0.667803985246;ESRRA:-0.678443173987;IRF1,2:-0.689729188616;FOXP3:-0.693977093104;JUN:-0.699656122669;BPTF:-0.70124979806;RUNX1..3:-0.702991933984;FOX{D1,D2}:-0.720879416837;AR:-0.744154628117;ATF2:-0.745524851422;NFE2L1:-0.786242122184;GFI1B:-0.816758836342;NFIX:-0.855502308127;MYFfamily:-0.866599162297;HMX1:-0.899059076897;TGIF1:-0.9128049549;XBP1:-0.929842054715;ATF6:-0.942503976334;SOX5:-0.965779718803;NHLH1,2:-0.98841805505;TLX2:-1.00553422787;GZF1:-1.01483748198;STAT2,4,6:-1.03612119476;DBP:-1.08933275278;ZNF238:-1.09800467748;NR3C1:-1.12804775485;MZF1:-1.16245291858;TAL1_TCF{3,4,12}:-1.24646121233;HBP1_HMGB_SSRP1_UBTF:-1.30136622434;SMAD1..7,9:-1.34894586322;SPZ1:-1.35530108304;NANOG{mouse}:-1.35882335548;STAT1,3:-1.38066899733;SRF:-1.39003359295;TFAP4:-1.46623337843;NFATC1..3:-1.55943664716;MAFB:-1.74338243337;RXRA_VDR{dimer}:-1.77991378541 | |top_motifs=SNAI1..3:1.88282920452;ZEB1:1.8186761173;bHLH_family:1.68369081768;VSX1,2:1.63451070309;ALX1:1.40382167113;POU1F1:1.40302025732;TOPORS:1.38609584829;FOX{I1,J2}:1.38222391572;NR6A1:1.05790632359;TP53:1.04851480616;HIF1A:1.03593929285;FOXQ1:1.00297776595;POU2F1..3:0.989752039561;CDX1,2,4:0.976851151039;ZBTB16:0.964808833949;MYOD1:0.959229680968;ZNF423:0.942321142761;NKX2-3_NKX2-5:0.882937599353;E2F1..5:0.845087360841;PITX1..3:0.840553102489;TFDP1:0.807462876523;LHX3,4:0.807119937032;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.782579984596;ELK1,4_GABP{A,B1}:0.766220618443;ONECUT1,2:0.752008018109;CDC5L:0.733394714459;FOXD3:0.713585692959;STAT5{A,B}:0.692771240882;YY1:0.672457639595;ADNP_IRX_SIX_ZHX:0.617012159027;TEF:0.602809786465;FOXM1:0.551478333654;PDX1:0.540846540809;FOXP1:0.504284098245;ZNF384:0.488850477838;BREu{core}:0.478246711332;NKX2-1,4:0.40901028;LMO2:0.392543884542;NFIL3:0.373265941303;AIRE:0.359264530454;HSF1,2:0.340624877353;HIC1:0.331764543981;NANOG:0.330682424554;IKZF1:0.323277618763;POU6F1:0.319064691198;NKX2-2,8:0.316645260663;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.296792835232;ARID5B:0.292911943435;HOX{A4,D4}:0.291481702967;PAX8:0.285186134152;NKX6-1,2:0.279428566766;NFY{A,B,C}:0.269588550203;RBPJ:0.262358455633;OCT4_SOX2{dimer}:0.201669814185;ZNF143:0.193827198726;TEAD1:0.181093025837;NKX3-2:0.171430808647;TBX4,5:0.168237373025;XCPE1{core}:0.161566626438;PAX1,9:0.15550959099;HAND1,2:0.142715167906;TFAP2{A,C}:0.139333994636;SP1:0.13064190287;HOX{A6,A7,B6,B7}:0.125697361122;PRRX1,2:0.122105187324;KLF4:0.118671849289;PBX1:0.110094706888;PAX4:0.104294184805;REST:0.0876412488953;IKZF2:0.0584420709035;ELF1,2,4:0.0413208932213;TLX1..3_NFIC{dimer}:0.0348957575286;UFEwm:0.034397183206;MTF1:0.0272912914842;NRF1:0.0174066132188;NFE2:0.000210423622018;RFX1:-0.00145572982237;FOSL2:-0.0104241026489;TFAP2B:-0.0146020939541;IRF7:-0.0173871331666;FOS_FOS{B,L1}_JUN{B,D}:-0.0188729172906;MYB:-0.0212869138888;PAX2:-0.0399314403037;PPARG:-0.0411967602997;HOX{A5,B5}:-0.0480805432103;GCM1,2:-0.0769135024015;ZNF148:-0.0847834550695;SOX17:-0.085391850278;ZBTB6:-0.090876645694;SOX{8,9,10}:-0.0931653578463;GTF2A1,2:-0.0948932218876;MED-1{core}:-0.106414207362;NR5A1,2:-0.10824538219;SOX2:-0.133763275109;BACH2:-0.139733017675;POU5F1:-0.140339881708;HNF4A_NR2F1,2:-0.157985352708;FOXL1:-0.176075148881;FOXA2:-0.189724684348;PAX6:-0.190288765124;PAX3,7:-0.200344777953;HNF1A:-0.202054609443;LEF1_TCF7_TCF7L1,2:-0.202694585766;PRDM1:-0.222286113916;ZIC1..3:-0.233581439381;TBP:-0.25520349783;MTE{core}:-0.258736035202;ESR1:-0.274192261584;GFI1:-0.274882258869;RORA:-0.290838384644;ATF4:-0.302723254665;FOXO1,3,4:-0.310384529602;FOXN1:-0.311855654307;EVI1:-0.323191766633;MYBL2:-0.329200154337;SREBF1,2:-0.330402758313;FOX{F1,F2,J1}:-0.333159724467;NFE2L2:-0.340868916129;AHR_ARNT_ARNT2:-0.348356923496;CEBPA,B_DDIT3:-0.361287929028;NFKB1_REL_RELA:-0.364328271159;CRX:-0.365252693199;RFX2..5_RFXANK_RFXAP:-0.371137421231;CUX2:-0.40018187059;NKX3-1:-0.403599643636;HES1:-0.405099693491;EN1,2:-0.408474738785;HMGA1,2:-0.416506113569;EGR1..3:-0.419654907779;PAX5:-0.428748239213;GATA6:-0.433165709119;RXR{A,B,G}:-0.458577894503;GATA4:-0.481034082798;DMAP1_NCOR{1,2}_SMARC:-0.505594875832;HLF:-0.514015830911;ATF5_CREB3:-0.521289561896;GTF2I:-0.535316543137;SPIB:-0.546168566995;GLI1..3:-0.557469327019;ETS1,2:-0.564770636992;ZFP161:-0.567376666209;PATZ1:-0.588536467471;SPI1:-0.591832336723;EBF1:-0.598825807375;HOXA9_MEIS1:-0.599014764908;TFCP2:-0.607431736157;T:-0.613073057289;RREB1:-0.615365777788;CREB1:-0.623985554988;ALX4:-0.628082091016;NR1H4:-0.62822875457;MEF2{A,B,C,D}:-0.639093211388;EP300:-0.649502614265;POU3F1..4:-0.660973266543;MAZ:-0.667803985246;ESRRA:-0.678443173987;IRF1,2:-0.689729188616;FOXP3:-0.693977093104;JUN:-0.699656122669;BPTF:-0.70124979806;RUNX1..3:-0.702991933984;FOX{D1,D2}:-0.720879416837;AR:-0.744154628117;ATF2:-0.745524851422;NFE2L1:-0.786242122184;GFI1B:-0.816758836342;NFIX:-0.855502308127;MYFfamily:-0.866599162297;HMX1:-0.899059076897;TGIF1:-0.9128049549;XBP1:-0.929842054715;ATF6:-0.942503976334;SOX5:-0.965779718803;NHLH1,2:-0.98841805505;TLX2:-1.00553422787;GZF1:-1.01483748198;STAT2,4,6:-1.03612119476;DBP:-1.08933275278;ZNF238:-1.09800467748;NR3C1:-1.12804775485;MZF1:-1.16245291858;TAL1_TCF{3,4,12}:-1.24646121233;HBP1_HMGB_SSRP1_UBTF:-1.30136622434;SMAD1..7,9:-1.34894586322;SPZ1:-1.35530108304;NANOG{mouse}:-1.35882335548;STAT1,3:-1.38066899733;SRF:-1.39003359295;TFAP4:-1.46623337843;NFATC1..3:-1.55943664716;MAFB:-1.74338243337;RXRA_VDR{dimer}:-1.77991378541 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10760-110E4;search_select_hide=table117:FF:10760-110E4 | |||
}} | }} |
Latest revision as of 15:03, 3 June 2020
Name: | bronchial squamous cell carcinoma cell line:KNS-62 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11862 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11862
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11862
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.585 |
10 | 10 | 0.996 |
100 | 100 | 0.0991 |
101 | 101 | 0.619 |
102 | 102 | 0.328 |
103 | 103 | 0.606 |
104 | 104 | 0.792 |
105 | 105 | 0.783 |
106 | 106 | 0.915 |
107 | 107 | 0.351 |
108 | 108 | 0.256 |
109 | 109 | 0.127 |
11 | 11 | 0.939 |
110 | 110 | 0.186 |
111 | 111 | 0.418 |
112 | 112 | 0.29 |
113 | 113 | 0.443 |
114 | 114 | 0.669 |
115 | 115 | 0.0332 |
116 | 116 | 0.852 |
117 | 117 | 0.921 |
118 | 118 | 1 |
119 | 119 | 0.2 |
12 | 12 | 0.459 |
120 | 120 | 0.638 |
121 | 121 | 0.727 |
122 | 122 | 0.873 |
123 | 123 | 0.0182 |
124 | 124 | 0.482 |
125 | 125 | 0.957 |
126 | 126 | 0.787 |
127 | 127 | 0.579 |
128 | 128 | 0.347 |
129 | 129 | 0.618 |
13 | 13 | 0.0865 |
130 | 130 | 0.835 |
131 | 131 | 0.108 |
132 | 132 | 0.147 |
133 | 133 | 0.0129 |
134 | 134 | 0.0321 |
135 | 135 | 0.0209 |
136 | 136 | 0.00694 |
137 | 137 | 0.0176 |
138 | 138 | 0.63 |
139 | 139 | 0.696 |
14 | 14 | 0.716 |
140 | 140 | 0.283 |
141 | 141 | 0.951 |
142 | 142 | 0.551 |
143 | 143 | 0.0342 |
144 | 144 | 0.234 |
145 | 145 | 0.687 |
146 | 146 | 0.911 |
147 | 147 | 0.392 |
148 | 148 | 0.811 |
149 | 149 | 0.43 |
15 | 15 | 0.365 |
150 | 150 | 0.405 |
151 | 151 | 0.507 |
152 | 152 | 0.315 |
153 | 153 | 0.371 |
154 | 154 | 0.722 |
155 | 155 | 0.454 |
156 | 156 | 0.327 |
157 | 157 | 0.968 |
158 | 158 | 0.231 |
159 | 159 | 0.516 |
16 | 16 | 0.791 |
160 | 160 | 0.736 |
161 | 161 | 0.601 |
162 | 162 | 0.469 |
163 | 163 | 0.274 |
164 | 164 | 0.283 |
165 | 165 | 0.842 |
166 | 166 | 0.209 |
167 | 167 | 0.38 |
168 | 168 | 0.45 |
169 | 169 | 0.819 |
17 | 17 | 0.839 |
18 | 18 | 0.193 |
19 | 19 | 0.0399 |
2 | 2 | 0.686 |
20 | 20 | 0.471 |
21 | 21 | 0.484 |
22 | 22 | 0.139 |
23 | 23 | 0.0186 |
24 | 24 | 0.891 |
25 | 25 | 0.678 |
26 | 26 | 0.801 |
27 | 27 | 0.756 |
28 | 28 | 0.645 |
29 | 29 | 0.412 |
3 | 3 | 0.982 |
30 | 30 | 0.96 |
31 | 31 | 0.321 |
32 | 32 | 0.00823 |
33 | 33 | 0.552 |
34 | 34 | 0.144 |
35 | 35 | 0.138 |
36 | 36 | 0.932 |
37 | 37 | 0.865 |
38 | 38 | 0.825 |
39 | 39 | 0.786 |
4 | 4 | 0.619 |
40 | 40 | 0.786 |
41 | 41 | 0.0395 |
42 | 42 | 0.92 |
43 | 43 | 0.0627 |
44 | 44 | 0.169 |
45 | 45 | 0.935 |
46 | 46 | 0.711 |
47 | 47 | 0.39 |
48 | 48 | 0.223 |
49 | 49 | 0.086 |
5 | 5 | 0.129 |
50 | 50 | 0.683 |
51 | 51 | 0.519 |
52 | 52 | 0.495 |
53 | 53 | 0.949 |
54 | 54 | 0.422 |
55 | 55 | 0.281 |
56 | 56 | 0.779 |
57 | 57 | 0.31 |
58 | 58 | 0.551 |
59 | 59 | 0.173 |
6 | 6 | 0.828 |
60 | 60 | 0.611 |
61 | 61 | 0.829 |
62 | 62 | 0.167 |
63 | 63 | 0.451 |
64 | 64 | 0.599 |
65 | 65 | 0.536 |
66 | 66 | 0.327 |
67 | 67 | 0.864 |
68 | 68 | 0.237 |
69 | 69 | 0.314 |
7 | 7 | 0.828 |
70 | 70 | 0.787 |
71 | 71 | 0.844 |
72 | 72 | 0.29 |
73 | 73 | 0.378 |
74 | 74 | 0.0661 |
75 | 75 | 0.592 |
76 | 76 | 0.393 |
77 | 77 | 0.439 |
78 | 78 | 0.225 |
79 | 79 | 0.226 |
8 | 8 | 0.644 |
80 | 80 | 5.78864e-4 |
81 | 81 | 0.171 |
82 | 82 | 0.024 |
83 | 83 | 0.166 |
84 | 84 | 0.466 |
85 | 85 | 0.0285 |
86 | 86 | 0.149 |
87 | 87 | 0.0796 |
88 | 88 | 0.268 |
89 | 89 | 0.784 |
9 | 9 | 0.0941 |
90 | 90 | 0.262 |
91 | 91 | 0.0876 |
92 | 92 | 0.164 |
93 | 93 | 0.59 |
94 | 94 | 0.286 |
95 | 95 | 0.201 |
96 | 96 | 0.0238 |
97 | 97 | 0.57 |
98 | 98 | 0.925 |
99 | 99 | 0.221 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11862
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0102024 squamous cell carcinoma cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000076 (squamous epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
305 (carcinoma)
1749 (squamous cell carcinoma)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0102024 (squamous cell carcinoma cell line sample)
0101120 (epithelial cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA