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MCL coexpression mm9:1496: Difference between revisions

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{{MCL_coexpression_mm9
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cell proliferation;0.000987627375769529;208154,19264!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.000987627375769529;208154,19264!GO:0002764;immune response-regulating signal transduction;0.000987627375769529;208154,19264!GO:0042129;regulation of T cell proliferation;0.000987627375769529;208154,19264!GO:0032944;regulation of mononuclear cell proliferation;0.000987627375769529;208154,19264!GO:0050670;regulation of lymphocyte proliferation;0.000987627375769529;208154,19264!GO:0042098;T cell proliferation;0.000987627375769529;208154,19264!GO:0050863;regulation of T cell activation;0.00113618692507234;208154,19264!GO:0032943;mononuclear cell proliferation;0.00125657145191464;208154,19264!GO:0046651;lymphocyte proliferation;0.00125657145191464;208154,19264!GO:0051249;regulation of lymphocyte activation;0.00130742180675326;208154,19264!GO:0042113;B cell activation;0.00130742180675326;208154,19264!GO:0050865;regulation of cell activation;0.00130742180675326;208154,19264!GO:0042110;T cell activation;0.00229019272800312;208154,19264!GO:0001915;negative regulation of T cell mediated cytotoxicity;0.00250650800414308;19264!GO:0003947;(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity;0.00250650800414308;14421!GO:0009897;external side of plasma membrane;0.00250650800414308;208154,19264!GO:0009986;cell surface;0.00364831547158889;208154,19264!GO:0046649;lymphocyte activation;0.00364831547158889;208154,19264!GO:0001960;negative regulation of cytokine and chemokine mediated signaling pathway;0.00364831547158889;19264!GO:0046642;negative regulation of alpha-beta T cell proliferation;0.00364831547158889;208154!GO:0045321;leukocyte activation;0.00364831547158889;208154,19264!GO:0001775;cell activation;0.00364831547158889;208154,19264!GO:0001916;positive regulation of T cell mediated cytotoxicity;0.00364831547158889;19264!GO:0051283;negative regulation of sequestering of calcium ion;0.00364831547158889;19264!GO:0001574;ganglioside biosynthetic process;0.00364831547158889;14421!GO:0051208;sequestering of calcium ion;0.00364831547158889;19264!GO:0002711;positive regulation of T cell mediated immunity;0.00364831547158889;19264!GO:0001959;regulation of cytokine and chemokine mediated signaling pathway;0.00364831547158889;19264!GO:0001914;regulation of T cell mediated cytotoxicity;0.00364831547158889;19264!GO:0051238;sequestering of metal ion;0.00364831547158889;19264!GO:0046636;negative regulation of alpha-beta T cell activation;0.00364831547158889;208154!GO:0051282;regulation of sequestering of calcium ion;0.00364831547158889;19264!GO:0050857;positive regulation of antigen receptor-mediated signaling pathway;0.00364831547158889;19264!GO:0051209;release of sequestered calcium ion into cytosol;0.00364831547158889;19264!GO:0002709;regulation of T cell mediated immunity;0.00436526650418391;19264!GO:0001911;negative regulation of leukocyte mediated cytotoxicity;0.00436526650418391;19264!GO:0030259;lipid glycosylation;0.00436526650418391;14421!GO:0001913;T cell mediated cytotoxicity;0.00436526650418391;19264!GO:0051239;regulation of multicellular organismal process;0.00444467753486734;208154,19264!GO:0006688;glycosphingolipid biosynthetic process;0.0051901239530375;14421!GO:0042127;regulation of cell proliferation;0.00549853888593896;208154,19264!GO:0050853;B cell receptor signaling pathway;0.00692745276002293;19264!GO:0001573;ganglioside metabolic process;0.00724289717845153;14421!GO:0002456;T cell mediated immunity;0.00724289717845153;19264!GO:0030889;negative regulation of B cell proliferation;0.00724289717845153;208154!GO:0009247;glycolipid biosynthetic process;0.00724289717845153;14421!GO:0046640;regulation of alpha-beta T cell proliferation;0.00781524904835845;208154!GO:0051607;defense response to virus;0.00781524904835845;19264!GO:0019915;sequestering of lipid;0.00834261915458024;14421!GO:0006687;glycosphingolipid metabolic process;0.00834261915458024;14421!GO:0050854;regulation of antigen receptor-mediated signaling pathway;0.00866657941083101;19264!GO:0050869;negative regulation of B cell activation;0.00866657941083101;208154!GO:0046634;regulation of alpha-beta T cell activation;0.00866657941083101;208154!GO:0008283;cell proliferation;0.0088796772213343;208154,19264!GO:0046633;alpha-beta T cell proliferation;0.0089563567987543;208154!GO:0001912;positive regulation of leukocyte mediated cytotoxicity;0.0089563567987543;19264!GO:0006955;immune response;0.00897164778533966;208154,19264!GO:0042130;negative regulation of T cell proliferation;0.00981593102114039;208154!GO:0002705;positive regulation of leukocyte mediated immunity;0.00981593102114039;19264!GO:0051235;maintenance of localization;0.00981593102114039;19264!GO:0031341;regulation of cell killing;0.00981593102114039;19264!GO:0002708;positive regulation of lymphocyte mediated immunity;0.00981593102114039;19264!GO:0030148;sphingolipid biosynthetic process;0.00981593102114039;14421!GO:0001910;regulation of leukocyte mediated cytotoxicity;0.00981593102114039;19264!GO:0002699;positive regulation of immune effector process;0.0101572226932141;19264!GO:0006664;glycolipid metabolic process;0.0101572226932141;14421!GO:0007204;elevation of cytosolic calcium ion concentration;0.0103289666262468;19264!GO:0002703;regulation of leukocyte mediated immunity;0.0103289666262468;19264!GO:0002706;regulation of lymphocyte mediated immunity;0.0103289666262468;19264!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.010344820902777;19264!GO:0050868;negative regulation of T cell activation;0.010344820902777;208154!GO:0008376;acetylgalactosaminyltransferase activity;0.010344820902777;14421!GO:0002821;positive regulation of adaptive immune response;0.010344820902777;19264!GO:0002697;regulation of immune effector process;0.0103589893539178;19264!GO:0050672;negative regulation of lymphocyte proliferation;0.0103589893539178;208154!GO:0051480;cytosolic calcium ion homeostasis;0.0103589893539178;19264!GO:0032945;negative regulation of mononuclear cell proliferation;0.0103589893539178;208154!GO:0030888;regulation of B cell proliferation;0.0112701985488289;208154!GO:0001909;leukocyte mediated cytotoxicity;0.0112701985488289;19264!GO:0001906;cell killing;0.0112701985488289;19264!GO:0002819;regulation of adaptive immune response;0.0112701985488289;19264!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0112701985488289;19264!GO:0006672;ceramide metabolic process;0.0115046148733659;14421!GO:0030258;lipid modification;0.0115046148733659;14421!GO:0030173;integral to Golgi membrane;0.0119416837886238;14421!GO:0046519;sphingoid metabolic process;0.0119416837886238;14421!GO:0031228;intrinsic to Golgi membrane;0.0119416837886238;14421!GO:0051250;negative regulation of lymphocyte activation;0.0119416837886238;208154!GO:0050851;antigen receptor-mediated signaling pathway;0.0124750958328535;19264!GO:0005925;focal adhesion;0.0124750958328535;19264!GO:0042102;positive regulation of T cell proliferation;0.0124750958328535;19264!GO:0002376;immune system process;0.0125726643711438;208154,19264!GO:0005924;cell-substrate adherens junction;0.0138679036118073;19264!GO:0046631;alpha-beta T cell activation;0.0138679036118073;208154!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.0141653615311815;19264!GO:0030055;cell-matrix junction;0.0147069576839938;19264!GO:0030183;B cell differentiation;0.0147069576839938;19264!GO:0048523;negative regulation of cellular process;0.0147069576839938;208154,19264!GO:0032946;positive regulation of mononuclear cell proliferation;0.0147069576839938;19264!GO:0002757;immune response-activating signal transduction;0.0147069576839938;19264!GO:0006469;negative regulation of protein kinase activity;0.0147069576839938;19264!GO:0033673;negative regulation of kinase activity;0.0147069576839938;19264!GO:0050671;positive regulation of lymphocyte proliferation;0.0147069576839938;19264!GO:0050864;regulation of B cell activation;0.0149707065010711;208154!GO:0051348;negative regulation of transferase activity;0.0152294350073338;19264!GO:0048519;negative regulation of biological process;0.0162830468959154;208154,19264!GO:0006665;sphingolipid metabolic process;0.0165171969946909;14421!GO:0050870;positive regulation of T cell activation;0.0167544030354514;19264!GO:0019221;cytokine and chemokine mediated signaling pathway;0.0173723752787155;19264!GO:0043086;negative regulation of catalytic activity;0.0179790452016474;19264!GO:0019901;protein kinase binding;0.0181966375578793;19264!GO:0009615;response to virus;0.0184103375493916;19264!GO:0019900;kinase binding;0.0184583324124759;19264!GO:0031301;integral to organelle membrane;0.0184583324124759;14421!GO:0031300;intrinsic to organelle membrane;0.020123610986793;14421!GO:0006874;cellular calcium ion homeostasis;0.0213896047952791;19264!GO:0005912;adherens junction;0.0213896047952791;19264!GO:0055074;calcium ion homeostasis;0.0213896047952791;19264!GO:0051251;positive regulation of lymphocyte activation;0.0213896047952791;19264!GO:0030217;T cell differentiation;0.0213896047952791;19264!GO:0006875;cellular metal ion homeostasis;0.0229468613137807;19264!GO:0055065;metal ion homeostasis;0.0234474349854449;19264!GO:0000139;Golgi membrane;0.0235990826085657;14421!GO:0016323;basolateral plasma membrane;0.0237482666926464;19264!GO:0046467;membrane lipid biosynthetic process;0.0242302665272944;14421!GO:0002253;activation of immune response;0.0257018337805838;19264!GO:0043413;biopolymer glycosylation;0.0261605319984295;14421!GO:0008194;UDP-glycosyltransferase activity;0.028029654037201;14421!GO:0004725;protein tyrosine phosphatase activity;0.028029654037201;19264!GO:0002250;adaptive immune response;0.0285632234116239;19264!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0285632234116239;19264!GO:0009968;negative regulation of signal transduction;0.0286654112364548;19264!GO:0030098;lymphocyte differentiation;0.0288651420565354;19264!GO:0002449;lymphocyte mediated immunity;0.0288651420565354;19264!GO:0030005;cellular di-, tri-valent inorganic cation homeostasis;0.0295823609825766;19264!GO:0050778;positive regulation of immune response;0.0296739229998401;19264!GO:0055066;di-, tri-valent inorganic cation homeostasis;0.0298529945699952;19264!GO:0002684;positive regulation of immune system process;0.0298529945699952;19264!GO:0002443;leukocyte mediated immunity;0.0299405620188862;19264!GO:0030003;cellular cation homeostasis;0.0312210729278844;19264!GO:0006470;protein amino acid dephosphorylation;0.031593914463362;19264!GO:0055080;cation homeostasis;0.0316672110673864;19264!GO:0050776;regulation of immune response;0.0324807880405482;19264!GO:0044459;plasma membrane part;0.0324807880405482;208154,19264!GO:0002682;regulation of immune system process;0.0327449710873612;19264!GO:0043412;biopolymer modification;0.0332728919083019;19264,14421!GO:0051240;positive regulation of multicellular organismal process;0.0332728919083019;19264!GO:0016311;dephosphorylation;0.0332728919083019;19264!GO:0008285;negative regulation of cell proliferation;0.0332728919083019;208154!GO:0002521;leukocyte differentiation;0.0353220015837589;19264!GO:0045859;regulation of protein kinase activity;0.0353220015837589;19264!GO:0006917;induction of apoptosis;0.0354084129998478;19264!GO:0012502;induction of programmed cell death;0.0354084129998478;19264!GO:0043549;regulation of kinase activity;0.0356539908169318;19264!GO:0044431;Golgi apparatus part;0.0356539908169318;14421!GO:0019899;enzyme binding;0.0356539908169318;19264!GO:0016758;transferase activity, transferring hexosyl groups;0.0356539908169318;14421!GO:0002252;immune effector process;0.0356539908169318;19264!GO:0051338;regulation of transferase activity;0.0356539908169318;19264!GO:0004721;phosphoprotein phosphatase activity;0.0377760273175131;19264!GO:0006873;cellular ion homeostasis;0.0378265910635761;19264!GO:0055082;cellular chemical homeostasis;0.0378265910635761;19264!GO:0006643;membrane lipid metabolic process;0.0388727940883598;14421!GO:0043065;positive regulation of apoptosis;0.0416802166691896;19264!GO:0051707;response to other organism;0.0416810069524464;19264!GO:0043068;positive regulation of programmed cell death;0.041681760089472;19264!GO:0050801;ion homeostasis;0.0416824767451136;19264!GO:0008284;positive regulation of cell proliferation;0.0439078312950332;19264!GO:0016021;integral to membrane;0.045164041073696;208154,19264,14421!GO:0031224;intrinsic to membrane;0.045164041073696;208154,19264,14421!GO:0005886;plasma 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|gostat_on_MCL_coexpression=GO:0042100;B cell proliferation;0.000987627375769529;208154,19264!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.000987627375769529;208154,19264!GO:0002764;immune response-regulating signal transduction;0.000987627375769529;208154,19264!GO:0042129;regulation of T cell proliferation;0.000987627375769529;208154,19264!GO:0032944;regulation of mononuclear cell proliferation;0.000987627375769529;208154,19264!GO:0050670;regulation of lymphocyte proliferation;0.000987627375769529;208154,19264!GO:0042098;T cell proliferation;0.000987627375769529;208154,19264!GO:0050863;regulation of T cell activation;0.00113618692507234;208154,19264!GO:0032943;mononuclear cell proliferation;0.00125657145191464;208154,19264!GO:0046651;lymphocyte proliferation;0.00125657145191464;208154,19264!GO:0051249;regulation of lymphocyte activation;0.00130742180675326;208154,19264!GO:0042113;B cell activation;0.00130742180675326;208154,19264!GO:0050865;regulation of cell activation;0.00130742180675326;208154,19264!GO:0042110;T cell activation;0.00229019272800312;208154,19264!GO:0001915;negative regulation of T cell mediated cytotoxicity;0.00250650800414308;19264!GO:0003947;(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity;0.00250650800414308;14421!GO:0009897;external side of plasma membrane;0.00250650800414308;208154,19264!GO:0009986;cell surface;0.00364831547158889;208154,19264!GO:0046649;lymphocyte activation;0.00364831547158889;208154,19264!GO:0001960;negative regulation of cytokine and chemokine mediated signaling pathway;0.00364831547158889;19264!GO:0046642;negative regulation of alpha-beta T cell proliferation;0.00364831547158889;208154!GO:0045321;leukocyte activation;0.00364831547158889;208154,19264!GO:0001775;cell activation;0.00364831547158889;208154,19264!GO:0001916;positive regulation of T cell mediated cytotoxicity;0.00364831547158889;19264!GO:0051283;negative regulation of sequestering of calcium ion;0.00364831547158889;19264!GO:0001574;ganglioside biosynthetic process;0.00364831547158889;14421!GO:0051208;sequestering of calcium ion;0.00364831547158889;19264!GO:0002711;positive regulation of T cell mediated immunity;0.00364831547158889;19264!GO:0001959;regulation of cytokine and chemokine mediated signaling pathway;0.00364831547158889;19264!GO:0001914;regulation of T cell mediated cytotoxicity;0.00364831547158889;19264!GO:0051238;sequestering of metal ion;0.00364831547158889;19264!GO:0046636;negative regulation of alpha-beta T cell activation;0.00364831547158889;208154!GO:0051282;regulation of sequestering of calcium ion;0.00364831547158889;19264!GO:0050857;positive regulation of antigen receptor-mediated signaling pathway;0.00364831547158889;19264!GO:0051209;release of sequestered calcium ion into cytosol;0.00364831547158889;19264!GO:0002709;regulation of T cell mediated immunity;0.00436526650418391;19264!GO:0001911;negative regulation of leukocyte mediated cytotoxicity;0.00436526650418391;19264!GO:0030259;lipid glycosylation;0.00436526650418391;14421!GO:0001913;T cell mediated cytotoxicity;0.00436526650418391;19264!GO:0051239;regulation of multicellular organismal process;0.00444467753486734;208154,19264!GO:0006688;glycosphingolipid biosynthetic process;0.0051901239530375;14421!GO:0042127;regulation of cell proliferation;0.00549853888593896;208154,19264!GO:0050853;B cell receptor signaling pathway;0.00692745276002293;19264!GO:0001573;ganglioside metabolic process;0.00724289717845153;14421!GO:0002456;T cell mediated immunity;0.00724289717845153;19264!GO:0030889;negative regulation of B cell proliferation;0.00724289717845153;208154!GO:0009247;glycolipid biosynthetic process;0.00724289717845153;14421!GO:0046640;regulation of alpha-beta T cell proliferation;0.00781524904835845;208154!GO:0051607;defense response to virus;0.00781524904835845;19264!GO:0019915;sequestering of lipid;0.00834261915458024;14421!GO:0006687;glycosphingolipid metabolic process;0.00834261915458024;14421!GO:0050854;regulation of antigen receptor-mediated signaling pathway;0.00866657941083101;19264!GO:0050869;negative regulation of B cell activation;0.00866657941083101;208154!GO:0046634;regulation of alpha-beta T cell activation;0.00866657941083101;208154!GO:0008283;cell proliferation;0.0088796772213343;208154,19264!GO:0046633;alpha-beta T cell proliferation;0.0089563567987543;208154!GO:0001912;positive regulation of leukocyte mediated cytotoxicity;0.0089563567987543;19264!GO:0006955;immune response;0.00897164778533966;208154,19264!GO:0042130;negative regulation of T cell proliferation;0.00981593102114039;208154!GO:0002705;positive regulation of leukocyte mediated immunity;0.00981593102114039;19264!GO:0051235;maintenance of localization;0.00981593102114039;19264!GO:0031341;regulation of cell killing;0.00981593102114039;19264!GO:0002708;positive regulation of lymphocyte mediated immunity;0.00981593102114039;19264!GO:0030148;sphingolipid biosynthetic process;0.00981593102114039;14421!GO:0001910;regulation of leukocyte mediated cytotoxicity;0.00981593102114039;19264!GO:0002699;positive regulation of immune effector process;0.0101572226932141;19264!GO:0006664;glycolipid metabolic process;0.0101572226932141;14421!GO:0007204;elevation of cytosolic calcium ion concentration;0.0103289666262468;19264!GO:0002703;regulation of leukocyte mediated immunity;0.0103289666262468;19264!GO:0002706;regulation of lymphocyte mediated immunity;0.0103289666262468;19264!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.010344820902777;19264!GO:0050868;negative regulation of T cell activation;0.010344820902777;208154!GO:0008376;acetylgalactosaminyltransferase activity;0.010344820902777;14421!GO:0002821;positive regulation of adaptive immune response;0.010344820902777;19264!GO:0002697;regulation of immune effector process;0.0103589893539178;19264!GO:0050672;negative regulation of lymphocyte proliferation;0.0103589893539178;208154!GO:0051480;cytosolic calcium ion homeostasis;0.0103589893539178;19264!GO:0032945;negative regulation of mononuclear cell proliferation;0.0103589893539178;208154!GO:0030888;regulation of B cell proliferation;0.0112701985488289;208154!GO:0001909;leukocyte mediated cytotoxicity;0.0112701985488289;19264!GO:0001906;cell killing;0.0112701985488289;19264!GO:0002819;regulation of adaptive immune response;0.0112701985488289;19264!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0112701985488289;19264!GO:0006672;ceramide metabolic process;0.0115046148733659;14421!GO:0030258;lipid modification;0.0115046148733659;14421!GO:0030173;integral to Golgi membrane;0.0119416837886238;14421!GO:0046519;sphingoid metabolic process;0.0119416837886238;14421!GO:0031228;intrinsic to Golgi membrane;0.0119416837886238;14421!GO:0051250;negative regulation of lymphocyte activation;0.0119416837886238;208154!GO:0050851;antigen receptor-mediated signaling pathway;0.0124750958328535;19264!GO:0005925;focal adhesion;0.0124750958328535;19264!GO:0042102;positive regulation of T cell proliferation;0.0124750958328535;19264!GO:0002376;immune system process;0.0125726643711438;208154,19264!GO:0005924;cell-substrate adherens junction;0.0138679036118073;19264!GO:0046631;alpha-beta T cell activation;0.0138679036118073;208154!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.0141653615311815;19264!GO:0030055;cell-matrix junction;0.0147069576839938;19264!GO:0030183;B cell differentiation;0.0147069576839938;19264!GO:0048523;negative regulation of cellular process;0.0147069576839938;208154,19264!GO:0032946;positive regulation of mononuclear cell proliferation;0.0147069576839938;19264!GO:0002757;immune response-activating signal transduction;0.0147069576839938;19264!GO:0006469;negative regulation of protein kinase activity;0.0147069576839938;19264!GO:0033673;negative regulation of kinase activity;0.0147069576839938;19264!GO:0050671;positive regulation of lymphocyte proliferation;0.0147069576839938;19264!GO:0050864;regulation of B cell activation;0.0149707065010711;208154!GO:0051348;negative regulation of transferase activity;0.0152294350073338;19264!GO:0048519;negative regulation of biological process;0.0162830468959154;208154,19264!GO:0006665;sphingolipid metabolic process;0.0165171969946909;14421!GO:0050870;positive regulation of T cell activation;0.0167544030354514;19264!GO:0019221;cytokine and chemokine mediated signaling pathway;0.0173723752787155;19264!GO:0043086;negative regulation of catalytic activity;0.0179790452016474;19264!GO:0019901;protein kinase binding;0.0181966375578793;19264!GO:0009615;response to virus;0.0184103375493916;19264!GO:0019900;kinase binding;0.0184583324124759;19264!GO:0031301;integral to organelle membrane;0.0184583324124759;14421!GO:0031300;intrinsic to organelle membrane;0.020123610986793;14421!GO:0006874;cellular calcium ion homeostasis;0.0213896047952791;19264!GO:0005912;adherens junction;0.0213896047952791;19264!GO:0055074;calcium ion homeostasis;0.0213896047952791;19264!GO:0051251;positive regulation of lymphocyte activation;0.0213896047952791;19264!GO:0030217;T cell differentiation;0.0213896047952791;19264!GO:0006875;cellular metal ion homeostasis;0.0229468613137807;19264!GO:0055065;metal ion homeostasis;0.0234474349854449;19264!GO:0000139;Golgi membrane;0.0235990826085657;14421!GO:0016323;basolateral plasma membrane;0.0237482666926464;19264!GO:0046467;membrane lipid biosynthetic process;0.0242302665272944;14421!GO:0002253;activation of immune response;0.0257018337805838;19264!GO:0043413;biopolymer glycosylation;0.0261605319984295;14421!GO:0008194;UDP-glycosyltransferase activity;0.028029654037201;14421!GO:0004725;protein tyrosine phosphatase activity;0.028029654037201;19264!GO:0002250;adaptive immune response;0.0285632234116239;19264!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0285632234116239;19264!GO:0009968;negative regulation of signal transduction;0.0286654112364548;19264!GO:0030098;lymphocyte differentiation;0.0288651420565354;19264!GO:0002449;lymphocyte mediated immunity;0.0288651420565354;19264!GO:0030005;cellular di-, tri-valent inorganic cation homeostasis;0.0295823609825766;19264!GO:0050778;positive regulation of immune response;0.0296739229998401;19264!GO:0055066;di-, tri-valent inorganic cation homeostasis;0.0298529945699952;19264!GO:0002684;positive regulation of immune system process;0.0298529945699952;19264!GO:0002443;leukocyte mediated immunity;0.0299405620188862;19264!GO:0030003;cellular cation homeostasis;0.0312210729278844;19264!GO:0006470;protein amino acid dephosphorylation;0.031593914463362;19264!GO:0055080;cation homeostasis;0.0316672110673864;19264!GO:0050776;regulation of immune response;0.0324807880405482;19264!GO:0044459;plasma membrane part;0.0324807880405482;208154,19264!GO:0002682;regulation of immune system process;0.0327449710873612;19264!GO:0043412;biopolymer modification;0.0332728919083019;19264,14421!GO:0051240;positive regulation of multicellular organismal process;0.0332728919083019;19264!GO:0016311;dephosphorylation;0.0332728919083019;19264!GO:0008285;negative regulation of cell proliferation;0.0332728919083019;208154!GO:0002521;leukocyte differentiation;0.0353220015837589;19264!GO:0045859;regulation of protein kinase activity;0.0353220015837589;19264!GO:0006917;induction of apoptosis;0.0354084129998478;19264!GO:0012502;induction of programmed cell death;0.0354084129998478;19264!GO:0043549;regulation of kinase activity;0.0356539908169318;19264!GO:0044431;Golgi apparatus part;0.0356539908169318;14421!GO:0019899;enzyme binding;0.0356539908169318;19264!GO:0016758;transferase activity, transferring hexosyl groups;0.0356539908169318;14421!GO:0002252;immune effector process;0.0356539908169318;19264!GO:0051338;regulation of transferase activity;0.0356539908169318;19264!GO:0004721;phosphoprotein phosphatase activity;0.0377760273175131;19264!GO:0006873;cellular ion homeostasis;0.0378265910635761;19264!GO:0055082;cellular chemical homeostasis;0.0378265910635761;19264!GO:0006643;membrane lipid metabolic process;0.0388727940883598;14421!GO:0043065;positive regulation of apoptosis;0.0416802166691896;19264!GO:0051707;response to other organism;0.0416810069524464;19264!GO:0043068;positive regulation of programmed cell death;0.041681760089472;19264!GO:0050801;ion homeostasis;0.0416824767451136;19264!GO:0008284;positive regulation of cell proliferation;0.0439078312950332;19264!GO:0016021;integral to membrane;0.045164041073696;208154,19264,14421!GO:0031224;intrinsic to membrane;0.045164041073696;208154,19264,14421!GO:0005886;plasma membrane;0.045164041073696;208154,19264!
}}

Latest revision as of 17:01, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:126602421..126602454,+p3@B4galnt1
Mm9::chr11:3004786..3004802,-p@chr11:3004786..3004802
-
Mm9::chr16:45224438..45224459,+p3@Btla
Mm9::chr16:45224470..45224477,+p@chr16:45224470..45224477
+
Mm9::chr1:140072269..140072281,-p7@Ptprc


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0042100B cell proliferation0.000987627375769529
GO:0002768immune response-regulating cell surface receptor signaling pathway0.000987627375769529
GO:0002764immune response-regulating signal transduction0.000987627375769529
GO:0042129regulation of T cell proliferation0.000987627375769529
GO:0032944regulation of mononuclear cell proliferation0.000987627375769529
GO:0050670regulation of lymphocyte proliferation0.000987627375769529
GO:0042098T cell proliferation0.000987627375769529
GO:0050863regulation of T cell activation0.00113618692507234
GO:0032943mononuclear cell proliferation0.00125657145191464
GO:0046651lymphocyte proliferation0.00125657145191464
GO:0051249regulation of lymphocyte activation0.00130742180675326
GO:0042113B cell activation0.00130742180675326
GO:0050865regulation of cell activation0.00130742180675326
GO:0042110T cell activation0.00229019272800312
GO:0001915negative regulation of T cell mediated cytotoxicity0.00250650800414308
GO:0003947(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity0.00250650800414308
GO:0009897external side of plasma membrane0.00250650800414308
GO:0009986cell surface0.00364831547158889
GO:0046649lymphocyte activation0.00364831547158889
GO:0001960negative regulation of cytokine and chemokine mediated signaling pathway0.00364831547158889
GO:0046642negative regulation of alpha-beta T cell proliferation0.00364831547158889
GO:0045321leukocyte activation0.00364831547158889
GO:0001775cell activation0.00364831547158889
GO:0001916positive regulation of T cell mediated cytotoxicity0.00364831547158889
GO:0051283negative regulation of sequestering of calcium ion0.00364831547158889
GO:0001574ganglioside biosynthetic process0.00364831547158889
GO:0051208sequestering of calcium ion0.00364831547158889
GO:0002711positive regulation of T cell mediated immunity0.00364831547158889
GO:0001959regulation of cytokine and chemokine mediated signaling pathway0.00364831547158889
GO:0001914regulation of T cell mediated cytotoxicity0.00364831547158889
GO:0051238sequestering of metal ion0.00364831547158889
GO:0046636negative regulation of alpha-beta T cell activation0.00364831547158889
GO:0051282regulation of sequestering of calcium ion0.00364831547158889
GO:0050857positive regulation of antigen receptor-mediated signaling pathway0.00364831547158889
GO:0051209release of sequestered calcium ion into cytosol0.00364831547158889
GO:0002709regulation of T cell mediated immunity0.00436526650418391
GO:0001911negative regulation of leukocyte mediated cytotoxicity0.00436526650418391
GO:0030259lipid glycosylation0.00436526650418391
GO:0001913T cell mediated cytotoxicity0.00436526650418391
GO:0051239regulation of multicellular organismal process0.00444467753486734
GO:0006688glycosphingolipid biosynthetic process0.0051901239530375
GO:0042127regulation of cell proliferation0.00549853888593896
GO:0050853B cell receptor signaling pathway0.00692745276002293
GO:0001573ganglioside metabolic process0.00724289717845153
GO:0002456T cell mediated immunity0.00724289717845153
GO:0030889negative regulation of B cell proliferation0.00724289717845153
GO:0009247glycolipid biosynthetic process0.00724289717845153
GO:0046640regulation of alpha-beta T cell proliferation0.00781524904835845
GO:0051607defense response to virus0.00781524904835845
GO:0019915sequestering of lipid0.00834261915458024
GO:0006687glycosphingolipid metabolic process0.00834261915458024
GO:0050854regulation of antigen receptor-mediated signaling pathway0.00866657941083101
GO:0050869negative regulation of B cell activation0.00866657941083101
GO:0046634regulation of alpha-beta T cell activation0.00866657941083101
GO:0008283cell proliferation0.0088796772213343
GO:0046633alpha-beta T cell proliferation0.0089563567987543
GO:0001912positive regulation of leukocyte mediated cytotoxicity0.0089563567987543
GO:0006955immune response0.00897164778533966
GO:0042130negative regulation of T cell proliferation0.00981593102114039
GO:0002705positive regulation of leukocyte mediated immunity0.00981593102114039
GO:0051235maintenance of localization0.00981593102114039
GO:0031341regulation of cell killing0.00981593102114039
GO:0002708positive regulation of lymphocyte mediated immunity0.00981593102114039
GO:0030148sphingolipid biosynthetic process0.00981593102114039
GO:0001910regulation of leukocyte mediated cytotoxicity0.00981593102114039
GO:0002699positive regulation of immune effector process0.0101572226932141
GO:0006664glycolipid metabolic process0.0101572226932141
GO:0007204elevation of cytosolic calcium ion concentration0.0103289666262468
GO:0002703regulation of leukocyte mediated immunity0.0103289666262468
GO:0002706regulation of lymphocyte mediated immunity0.0103289666262468
GO:0002824positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains0.010344820902777
GO:0050868negative regulation of T cell activation0.010344820902777
GO:0008376acetylgalactosaminyltransferase activity0.010344820902777
GO:0002821positive regulation of adaptive immune response0.010344820902777
GO:0002697regulation of immune effector process0.0103589893539178
GO:0050672negative regulation of lymphocyte proliferation0.0103589893539178
GO:0051480cytosolic calcium ion homeostasis0.0103589893539178
GO:0032945negative regulation of mononuclear cell proliferation0.0103589893539178
GO:0030888regulation of B cell proliferation0.0112701985488289
GO:0001909leukocyte mediated cytotoxicity0.0112701985488289
GO:0001906cell killing0.0112701985488289
GO:0002819regulation of adaptive immune response0.0112701985488289
GO:0002822regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.0.0112701985488289
GO:0006672ceramide metabolic process0.0115046148733659
GO:0030258lipid modification0.0115046148733659
GO:0030173integral to Golgi membrane0.0119416837886238
GO:0046519sphingoid metabolic process0.0119416837886238
GO:0031228intrinsic to Golgi membrane0.0119416837886238
GO:0051250negative regulation of lymphocyte activation0.0119416837886238
GO:0050851antigen receptor-mediated signaling pathway0.0124750958328535
GO:0005925focal adhesion0.0124750958328535
GO:0042102positive regulation of T cell proliferation0.0124750958328535
GO:0002376immune system process0.0125726643711438
GO:0005924cell-substrate adherens junction0.0138679036118073
GO:0046631alpha-beta T cell activation0.0138679036118073
GO:0002429immune response-activating cell surface receptor signaling pathway0.0141653615311815
GO:0030055cell-matrix junction0.0147069576839938
GO:0030183B cell differentiation0.0147069576839938
GO:0048523negative regulation of cellular process0.0147069576839938
GO:0032946positive regulation of mononuclear cell proliferation0.0147069576839938
GO:0002757immune response-activating signal transduction0.0147069576839938
GO:0006469negative regulation of protein kinase activity0.0147069576839938
GO:0033673negative regulation of kinase activity0.0147069576839938
GO:0050671positive regulation of lymphocyte proliferation0.0147069576839938
GO:0050864regulation of B cell activation0.0149707065010711
GO:0051348negative regulation of transferase activity0.0152294350073338
GO:0048519negative regulation of biological process0.0162830468959154
GO:0006665sphingolipid metabolic process0.0165171969946909
GO:0050870positive regulation of T cell activation0.0167544030354514
GO:0019221cytokine and chemokine mediated signaling pathway0.0173723752787155
GO:0043086negative regulation of catalytic activity0.0179790452016474
GO:0019901protein kinase binding0.0181966375578793
GO:0009615response to virus0.0184103375493916
GO:0019900kinase binding0.0184583324124759
GO:0031301integral to organelle membrane0.0184583324124759
GO:0031300intrinsic to organelle membrane0.020123610986793
GO:0006874cellular calcium ion homeostasis0.0213896047952791
GO:0005912adherens junction0.0213896047952791
GO:0055074calcium ion homeostasis0.0213896047952791
GO:0051251positive regulation of lymphocyte activation0.0213896047952791
GO:0030217T cell differentiation0.0213896047952791
GO:0006875cellular metal ion homeostasis0.0229468613137807
GO:0055065metal ion homeostasis0.0234474349854449
GO:0000139Golgi membrane0.0235990826085657
GO:0016323basolateral plasma membrane0.0237482666926464
GO:0046467membrane lipid biosynthetic process0.0242302665272944
GO:0002253activation of immune response0.0257018337805838
GO:0043413biopolymer glycosylation0.0261605319984295
GO:0008194UDP-glycosyltransferase activity0.028029654037201
GO:0004725protein tyrosine phosphatase activity0.028029654037201
GO:0002250adaptive immune response0.0285632234116239
GO:0002460adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains0.0285632234116239
GO:0009968negative regulation of signal transduction0.0286654112364548
GO:0030098lymphocyte differentiation0.0288651420565354
GO:0002449lymphocyte mediated immunity0.0288651420565354
GO:0030005cellular di-, tri-valent inorganic cation homeostasis0.0295823609825766
GO:0050778positive regulation of immune response0.0296739229998401
GO:0055066di-, tri-valent inorganic cation homeostasis0.0298529945699952
GO:0002684positive regulation of immune system process0.0298529945699952
GO:0002443leukocyte mediated immunity0.0299405620188862
GO:0030003cellular cation homeostasis0.0312210729278844
GO:0006470protein amino acid dephosphorylation0.031593914463362
GO:0055080cation homeostasis0.0316672110673864
GO:0050776regulation of immune response0.0324807880405482
GO:0044459plasma membrane part0.0324807880405482
GO:0002682regulation of immune system process0.0327449710873612
GO:0043412biopolymer modification0.0332728919083019
GO:0051240positive regulation of multicellular organismal process0.0332728919083019
GO:0016311dephosphorylation0.0332728919083019
GO:0008285negative regulation of cell proliferation0.0332728919083019
GO:0002521leukocyte differentiation0.0353220015837589
GO:0045859regulation of protein kinase activity0.0353220015837589
GO:0006917induction of apoptosis0.0354084129998478
GO:0012502induction of programmed cell death0.0354084129998478
GO:0043549regulation of kinase activity0.0356539908169318
GO:0044431Golgi apparatus part0.0356539908169318
GO:0019899enzyme binding0.0356539908169318
GO:0016758transferase activity, transferring hexosyl groups0.0356539908169318
GO:0002252immune effector process0.0356539908169318
GO:0051338regulation of transferase activity0.0356539908169318
GO:0004721phosphoprotein phosphatase activity0.0377760273175131
GO:0006873cellular ion homeostasis0.0378265910635761
GO:0055082cellular chemical homeostasis0.0378265910635761
GO:0006643membrane lipid metabolic process0.0388727940883598
GO:0043065positive regulation of apoptosis0.0416802166691896
GO:0051707response to other organism0.0416810069524464
GO:0043068positive regulation of programmed cell death0.041681760089472
GO:0050801ion homeostasis0.0416824767451136
GO:0008284positive regulation of cell proliferation0.0439078312950332
GO:0016021integral to membrane0.045164041073696
GO:0031224intrinsic to membrane0.045164041073696
GO:0005886plasma membrane0.045164041073696



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
mature alpha-beta T cell6.00e-139
alpha-beta T cell6.00e-139
immature T cell6.00e-139
mature T cell6.00e-139
immature alpha-beta T cell6.00e-139
hematopoietic lineage restricted progenitor cell1.05e-1125
CD4-positive, alpha-beta T cell1.18e-118
lymphoid lineage restricted progenitor cell2.52e-1112
hematopoietic cell4.35e-1132
hematopoietic oligopotent progenitor cell4.35e-1132
hematopoietic stem cell4.35e-1132
angioblastic mesenchymal cell4.35e-1132
hematopoietic multipotent progenitor cell4.35e-1132
lymphocyte3.20e-1013
common lymphoid progenitor3.20e-1013
T cell4.11e-1011
pro-T cell4.11e-1011
thymocyte1.65e-096
double negative thymocyte1.65e-096
naive T cell1.65e-096
double-positive, alpha-beta thymocyte1.65e-096
CD4-positive, alpha-beta thymocyte1.65e-096
naive thymus-derived CD4-positive, alpha-beta T cell1.65e-096
DN4 thymocyte1.65e-096
DN1 thymic pro-T cell1.65e-096
DN2 thymocyte1.65e-096
DN3 thymocyte1.65e-096
immature single positive thymocyte1.65e-096
early T lineage precursor1.65e-096
mature CD4 single-positive thymocyte1.65e-096
resting double-positive thymocyte1.65e-096
double-positive blast1.65e-096
CD69-positive double-positive thymocyte1.65e-096
CD69-positive, CD4-positive single-positive thymocyte1.65e-096
CD4-positive, CD8-intermediate double-positive thymocyte1.65e-096
CD24-positive, CD4 single-positive thymocyte1.65e-096
megakaryocyte progenitor cell1.52e-086
megakaryocyte1.52e-086
nucleate cell9.28e-0816
leukocyte3.88e-0717
nongranular leukocyte3.88e-0717

Uber Anatomy
Ontology termp-valuen
hemolymphoid system9.83e-2648
immune system9.83e-2648
hemopoietic organ1.20e-2229
immune organ1.20e-2229
hematopoietic system1.79e-2245
blood island1.79e-2245
gland of gut9.64e-2024
thymus1.14e-1823
neck1.14e-1823
respiratory system epithelium1.14e-1823
hemolymphoid system gland1.14e-1823
pharyngeal epithelium1.14e-1823
thymic region1.14e-1823
pharyngeal gland1.14e-1823
entire pharyngeal arch endoderm1.14e-1823
thymus primordium1.14e-1823
early pharyngeal endoderm1.14e-1823
pharynx1.28e-1724
upper respiratory tract1.28e-1724
chordate pharynx1.28e-1724
pharyngeal arch system1.28e-1724
pharyngeal region of foregut1.28e-1724
mixed endoderm/mesoderm-derived structure2.27e-1735
foregut4.37e-1580
segment of respiratory tract5.94e-1527
respiratory system4.81e-1442
respiratory tract3.62e-1341
organ segment2.26e-1135
craniocervical region5.77e-1136
digestive system7.54e-11116
digestive tract7.54e-11116
primitive gut7.54e-11116
endoderm-derived structure1.88e-10118
endoderm1.88e-10118
presumptive endoderm1.88e-10118
lateral plate mesoderm8.04e-1087
endo-epithelium8.96e-1069
subdivision of digestive tract1.09e-09114
gut epithelium1.80e-0955
endocrine gland8.90e-0960
gland2.23e-0865
unilaminar epithelium3.04e-0866
anterior region of body3.42e-0843
mesoderm4.63e-07120
mesoderm-derived structure4.63e-07120
presumptive mesoderm4.63e-07120
endocrine system9.70e-0772


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0833043
MA0004.11.46913
MA0006.10.419915
MA0007.10.587678
MA0009.11.06266
MA0014.10.0502051
MA0017.10.449113
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.10.43138
MA0029.10.995171
MA0030.11.00195
MA0031.10.965177
MA0038.10.757669
MA0040.11.07552
MA0041.10.522007
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.10.205696
MA0050.10.645342
MA0051.10.767098
MA0052.11.08379
MA0055.10.0851423
MA0056.10
MA0057.10.192781
MA0058.10.50032
MA0059.10.513699
MA0060.10.330907
MA0061.10.364227
MA0063.10
MA0066.10.746072
MA0067.11.41352
MA0068.10.197245
MA0069.11.08414
MA0070.11.07418
MA0071.10.644448
MA0072.11.06547
MA0073.10.000589538
MA0074.10.708108
MA0076.10.470037
MA0077.11.04318
MA0078.10.801834
MA0081.11.33193
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.10.148348
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.11.12162
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.10.460936
MA0105.10.693075
MA0106.10.809991
MA0107.10.454197
MA0108.20.897859
MA0109.10
MA0111.10.582193
MA0113.10.780358
MA0114.10.361633
MA0115.11.16466
MA0116.10.419688
MA0117.11.13165
MA0119.10.524046
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.10.869325
MA0132.10
MA0133.10
MA0135.19.99086
MA0136.10.729175
MA0139.10.295945
MA0140.10.695713
MA0141.10.482463
MA0142.10.950155
MA0143.10.797553
MA0144.10.365053
MA0145.10.476962
MA0146.10.822925
MA0147.10.986917
MA0148.10.621195
MA0149.10.529387
MA0062.20.254018
MA0035.20.700704
MA0039.20.0511423
MA0138.20.861035
MA0002.21.47075
MA0137.20.479301
MA0104.20.845917
MA0047.20.75686
MA0112.20.157681
MA0065.20.158101
MA0150.11.43499
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.10.203217
MA0155.10.173445
MA0156.10.469089
MA0157.10.91689
MA0158.10
MA0159.10.389847
MA0160.10.624415
MA0161.10
MA0162.10.245828
MA0163.10.0644585
MA0164.10.729558
MA0080.21.15331
MA0018.20.739807
MA0099.20.854449
MA0079.20.00167664
MA0102.21.79669
MA0258.10.91616
MA0259.10.960816
MA0442.10
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