CL:0000553
From FANTOM5_SSTAR
Name: | megakaryocyte progenitor cell | |
---|---|---|
Namespace: | FANTOM | |
Definition: | "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] | |
Xrefs: |
| |
Synonyms: |
"CFU-Meg" EXACT [PMID:11722431, PMID:12482498] "colony-forming unit-megakaryocyte" EXACT [] "Meg-CFC" EXACT [PMCID:PMC1794060] "megacaryoblast" EXACT [] "megacaryocyte progenitor cell" EXACT [] "megakaryoblast" EXACT [] "megakaryocytic progenitor cell" EXACT [PMID:12482498] "promegacaryocyte" RELATED [] "promegakaryocyte" RELATED [] | |
Comments: | Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | CL:0000763(myeloid cell),CL:0000839(myeloid lineage restricted progenitor cell) |
---|---|
develops_from: | CL:0000050(megakaryocyte-erythroid progenitor cell) |
Children
is a: | CL:0002024 (Kit-positive megakaryocyte progenitor cell) |
---|---|
develops from: | CL:0000556 (megakaryocyte) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000553 (megakaryocyte progenitor cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data