MCL coexpression mm9:1230

Phase1 CAGE Peaks

	Short description
Mm9::chr10:128181040..128181051,-	p6@Dgka
Mm9::chr12:4914035..4914063,-	p3@Ubxn2a
Mm9::chr13:39052367..39052408,-	p1@Slc35b3
Mm9::chr14:47896665..47896684,+	p2@Socs4
Mm9::chr17:31433136..31433198,+	p1@Slc37a1
Mm9::chr8:72519989..72520007,-	p5@Gatad2a

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0015794	glycerol-3-phosphate transport	0.00633946670214681
GO:0015168	glycerol transmembrane transporter activity	0.00633946670214681
GO:0015665	alcohol transmembrane transporter activity	0.00633946670214681
GO:0015793	glycerol transport	0.00633946670214681
GO:0015169	glycerol-3-phosphate transmembrane transporter activity	0.00633946670214681
GO:0015166	polyol transmembrane transporter activity	0.00633946670214681
GO:0006127	glycerophosphate shuttle	0.00633946670214681
GO:0021995	neuropore closure	0.00887428085907578
GO:0015791	polyol transport	0.00887428085907578
GO:0021506	anterior neuropore closure	0.00887428085907578
GO:0001842	neural fold formation	0.0120999660568884
GO:0010172	embryonic body morphogenesis	0.0147872268848731
GO:0010171	body morphogenesis	0.0170603152436236
GO:0006072	glycerol-3-phosphate metabolic process	0.0190079824906938
GO:0007205	protein kinase C activation	0.0332421055492497
GO:0004143	diacylglycerol kinase activity	0.0332421055492497
GO:0006071	glycerol metabolic process	0.049204409131596
GO:0019751	polyol metabolic process	0.049204409131596

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
lymphoid lineage restricted progenitor cell	1.02e-07	12
T cell	2.97e-07	11
pro-T cell	2.97e-07	11
mature alpha-beta T cell	7.67e-07	9
alpha-beta T cell	7.67e-07	9
immature T cell	7.67e-07	9
mature T cell	7.67e-07	9
immature alpha-beta T cell	7.67e-07	9

Uber Anatomy

Ontology term	p-value	n
endoderm-derived structure	2.70e-23	118
endoderm	2.70e-23	118
presumptive endoderm	2.70e-23	118
digestive system	7.99e-23	116
digestive tract	7.99e-23	116
primitive gut	7.99e-23	116
subdivision of digestive tract	1.20e-21	114
gastrointestinal system	4.93e-14	47
intestine	7.78e-14	31
endo-epithelium	4.49e-11	69
gut epithelium	1.18e-10	55
organ component layer	4.36e-10	24
mucosa	5.72e-10	15
intestinal mucosa	6.29e-09	13
anatomical wall	6.29e-09	13
wall of intestine	6.29e-09	13
gastrointestinal system mucosa	6.29e-09	13
foregut	1.71e-08	80
unilaminar epithelium	2.06e-08	66
mixed endoderm/mesoderm-derived structure	7.70e-08	35
hemolymphoid system	4.26e-07	48
immune system	4.26e-07	48
hemopoietic organ	7.47e-07	29
immune organ	7.47e-07	29

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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