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Coexpression cluster:C1746

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Full id: C1746_kidney_renal_Renal_mesothelioma_endometrial_Preadipocyte_Astrocyte



Phase1 CAGE Peaks

Hg19::chr15:66420804..66420837,-p4@MEGF11
Hg19::chr9:133986709..133986719,+p13@AIF1L
Hg19::chr9:133986740..133986750,+p7@AIF1L
Hg19::chr9:133986782..133986794,+p4@AIF1L
Hg19::chr9:133986807..133986821,+p3@AIF1L


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0016323basolateral plasma membrane0.0200164841634287



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
renal tubule2.74e-2312
nephron tubule2.74e-2312
nephron tubule epithelium2.74e-2312
nephron epithelium3.69e-2316
nephron3.69e-2316
uriniferous tubule3.69e-2316
metanephric mesenchyme3.69e-2316
nephrogenic mesenchyme3.69e-2316
kidney3.20e-2227
kidney mesenchyme3.20e-2227
kidney rudiment3.20e-2227
kidney field3.20e-2227
excretory tube1.40e-2117
mesonephric epithelium1.40e-2117
mesonephric tubule1.40e-2117
nephric duct1.40e-2117
kidney epithelium1.40e-2117
renal duct1.40e-2117
mesonephric duct1.40e-2117
pronephric duct1.40e-2117
mesonephros3.55e-2018
pronephros3.55e-2018
nephrogenic cord3.55e-2018
pronephric mesoderm3.55e-2018
rostral part of nephrogenic cord3.55e-2018
presumptive pronephric mesoderm3.55e-2018
intraembryonic coelom3.52e-1921
cavitated compound organ5.93e-1832
urogenital ridge8.57e-1820
cortex of kidney7.24e-1713
renal parenchyma7.24e-1713
regional part of nervous system1.37e-1394
nervous system1.37e-1394
regional part of brain1.59e-1359
abdomen element2.73e-1355
abdominal segment element2.73e-1355
cortex3.06e-1316
central nervous system4.11e-1382
duct7.25e-1326
neural tube9.18e-1357
neural rod9.18e-1357
future spinal cord9.18e-1357
neural keel9.18e-1357
brain1.14e-1269
future brain1.14e-1269
neural plate2.47e-1286
presumptive neural plate2.47e-1286
parenchyma2.56e-1217
pre-chordal neural plate8.51e-1261
urinary system structure9.96e-1244
neurectoderm1.82e-1190
abdominal segment of trunk2.06e-1161
abdomen2.06e-1161
renal system2.31e-1145
regional part of forebrain4.77e-1041
forebrain4.77e-1041
future forebrain4.77e-1041
organ part5.87e-10219
telencephalon8.51e-1034
gray matter9.63e-1034
brain grey matter9.63e-1034
anterior neural tube1.02e-0942
head2.85e-09123
cerebral hemisphere4.53e-0932
regional part of telencephalon9.17e-0933
renal cortex tubule1.39e-083
region of nephron tubule1.39e-083
proximal tubule1.39e-083
anterior region of body1.72e-08129
craniocervical region1.72e-08129
tube1.84e-08194
intermediate mesoderm4.77e-0837
renal glomerulus5.10e-087
renal corpuscle5.10e-087
glomerular capsule5.10e-087
glomerular tuft5.10e-087


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.