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Coexpression cluster:C1722: Difference between revisions

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|tf_chipseq_enrich=CTCF#10664;4:4.28820509846002:0.00515201558824328:0.0239313003033508!SUZ12#23512;4:40.0926247288503:7.78750287036555e-07:3.41014260913253e-05
|tf_chipseq_enrich=CTCF#10664;4:4.28820509846002:0.00515201558824328:0.0239313003033508!SUZ12#23512;4:40.0926247288503:7.78750287036555e-07:3.41014260913253e-05
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}}
}}

Revision as of 15:03, 26 November 2012


Full id: C1722_Nucleus_Anulus_parotid_Fibroblast_salivary_Olfactory_trachea



Phase1 CAGE Peaks

Hg19::chr14:37126141..37126157,-p@chr14:37126141..37126157
-
Hg19::chr14:37126765..37126799,+p2@PAX9
Hg19::chr14:37126814..37126834,+p4@PAX9
Hg19::chr14:37126852..37126863,+p2@ENST00000555639
Hg19::chr14:37126870..37126882,+p1@ENST00000555639


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0007492endoderm development0.00980219003885553



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
mouth2.72e-5529
stomodeum2.72e-5529
oral opening4.48e-3622
anterior region of body1.42e-3162
craniocervical region1.42e-3162
subdivision of skeletal system1.85e-3116
subdivision of head1.00e-3049
orifice3.80e-2736
gland of gut1.31e-2610
head2.81e-2656
saliva-secreting gland9.35e-266
gland of oral region9.35e-266
gland of foregut9.35e-266
oral gland9.35e-266
oral cavity9.35e-266
axial skeletal system6.67e-2414
intervertebral cartilage1.21e-225
symphysis1.21e-225
nonsynovial joint1.21e-225
fibrous joint1.21e-225
cartilaginous joint1.21e-225
developing mesenchymal condensation1.21e-225
pre-cartilage condensation1.21e-225
cartilaginous condensation1.21e-225
cartilage element1.21e-225
post-cranial axial skeletal system1.21e-225
vertebral column1.21e-225
intervertebral disk1.21e-225
intervertebral joint1.21e-225
digestive system1.49e-19145
digestive tract1.49e-19145
primitive gut1.49e-19145
articulation1.50e-198
skeletal joint1.50e-198
articular system1.50e-198
respiratory system1.08e-1874
periodontium5.79e-186
dentition5.79e-186
endoderm-derived structure4.37e-17160
endoderm4.37e-17160
presumptive endoderm4.37e-17160
surface structure8.17e-1699
skull2.30e-157
nucleus pulposus5.86e-143
axial mesoderm5.86e-143
notochord5.86e-143
chordamesoderm5.86e-143
cranial skeletal system7.74e-1411
organ system subdivision3.63e-11223
chordate pharynx1.47e-1010
pharyngeal region of foregut1.47e-1010
annulus fibrosus1.93e-102
fibrocartilage1.93e-102
annulus fibrosus disci intervertebralis1.93e-102
foregut2.47e-1087
midface2.90e-102
major salivary gland4.54e-102
open tracheal system trachea6.20e-102
pharynx1.42e-0911
gingiva3.43e-098
organism subdivision1.33e-08264
subdivision of digestive tract1.66e-08118
multi-tissue structure2.16e-08342
anatomical cluster2.40e-08373
mouth mucosa3.13e-0813
mucosa2.54e-0720
cartilage tissue3.22e-073
skeletal tissue3.22e-073
esophagus9.28e-073
esophageal region9.28e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
CTCF#1066444.288205098460020.005152015588243280.0239313003033508
SUZ12#23512440.09262472885037.78750287036555e-073.41014260913253e-05



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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