FF:11885-125D4: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004980 | ||
| | |accession_numbers=CAGE;DRX008161;DRR009033;DRZ000458;DRZ001843;DRZ011808;DRZ013193 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000335,FF:0011108 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!3.84!6905.53!PLEK;;chr7:115670804..115670825,-!p1@TFEC!3.06!1155.09!TFEC;;chr11:47400078..47400106,-!p1@SPI1!2.84!684.82!SPI1;;chr16:85932760..85932775,+!p1@IRF8!2.64!438.93!IRF8;;chr3:101546827..101546847,+!p2@NFKBIZ!2.36!317.41!NFKBIZ;;chr10:104155659..104155676,+!p4@NFKB2!2.21!200.00!NFKB2;;chr14:35872453..35872485,-!p2@NFKBIA!2.20!370.58!NFKBIA;;chr10:51572408..51572454,+!p3@NCOA4!2.18!831.35!NCOA4;;chr11:47400062..47400077,-!p2@SPI1!2.17!147.79!SPI1;;chr2:192015701..192015743,-!p1@STAT4!2.16!192.73!STAT4;;chr2:68592394..68592405,+!p2@PLEK!2.13!133.55!PLEK;;chr14:35873947..35873965,-!p1@NFKBIA!2.06!6621.66!NFKBIA;;chr2:70142232..70142251,+!p1@MXD1!2.05!589.25!MXD1;;chr12:72056800..72056834,+!p1@THAP2!2.04!145.26!THAP2;;chr20:39317868..39317884,-!p1@MAFB!2.02!1139.26!MAFB;;chr11:47399947..47399961,-!p3@SPI1!2.02!104.12!SPI1;;chr6:106534192..106534224,+!p1@PRDM1!2.00!267.73!PRDM1;;chr21:30671690..30671762,+!p2@BACH1!1.99!313.30!BACH1;;chr10:31288398..31288455,-!p2@ZNF438!1.99!111.39!ZNF438;;chr10:64018918..64018936,+!p2@ZNF365!1.96!91.14!ZNF365;;chr16:31885093..31885165,+!p1@ZNF267!1.94!1241.17!ZNF267;;chr12:54778471..54778528,-!p1@ZNF385A!1.94!85.13!ZNF385A;;chr21:34442439..34442455,+!p1@OLIG1!1.94!85.13!OLIG1;;chr21:30673091..30673135,+!p7@BACH1!1.93!84.81!BACH1;;chr2:145277640..145277771,-!p1@ZEB2!1.92!1022.81!ZEB2;;chr2:61108695..61108753,+!p1@REL!1.91!516.47!REL;;chr1:38325227..38325246,-!p2@MTF1!1.91!108.23!MTF1;;chr4:103422499..103422632,+!p1@NFKB1!1.89!1483.58!NFKB1;;chr6:126240380..126240430,+!p2@NCOA7!1.89!191.14!NCOA7;;chr10:64576105..64576133,-!p1@EGR2!1.86!142.09!EGR2;;chr5:142782823..142782854,-!p3@NR3C1!1.84!96.84!NR3C1;;chr12:72056749..72056767,+!p6@THAP2!1.84!75.95!THAP2;;chr19:45971246..45971265,+!p1@FOSB!1.83!1157.94!FOSB;;chr10:104155480..104155534,+!p2@NFKB2!1.83!413.62!NFKB2;;chr11:47400032..47400043,-!p5@SPI1!1.82!65.19!SPI1;;chr10:51572339..51572376,+!p4@NCOA4!1.81!138.93!NCOA4;;chr3:101568349..101568365,+!p1@NFKBIZ!1.80!3029.49!NFKBIZ;;chr2:145275162..145275202,-!p2@ZEB2!1.80!345.58!ZEB2;;chr1:37940170..37940190,+!p1@ZC3H12A!1.79!708.24!ZC3H12A;;chrX:153305787..153305807,-!p3@MECP2!1.79!60.44!MECP2;;chr18:77155922..77155939,+!p1@NFATC1!1.77!151.90!NFATC1;;chr7:50344289..50344323,+!p1@IKZF1!1.77!57.91!IKZF1;;chr12:72056773..72056796,+!p3@THAP2!1.76!73.10!THAP2;;chr7:115670792..115670797,-!p2@TFEC!1.73!52.22!TFEC;;chr21:30671235..30671253,+!p1@BACH1!1.71!600.33!BACH1;;chr11:615942..615957,-!p1@IRF7!1.70!436.09!IRF7;;chr10:104154246..104154347,+!p3@NFKB2!1.70!283.55!NFKB2;;chr11:65430554..65430579,-!p3@RELA!1.69!118.67!RELA;;chr8:123793988..123794016,+!p1@ZHX2!1.69!81.96!ZHX2;;chr6:106534230..106534254,+!p2@PRDM1!1.67!110.76!PRDM1;;chr10:31288370..31288393,-!p3@ZNF438!1.67!46.20!ZNF438;;chr11:47399996..47400014,-!p4@SPI1!1.67!45.25!SPI1;;chr14:35872494..35872511,-!p5@NFKBIA!1.64!55.38!NFKBIA;;chr2:68615063..68615089,+!p4@PLEK!1.64!42.72!PLEK;;chr6:12012170..12012245,+!p1@HIVEP1!1.63!200.32!HIVEP1;;chr9:102584262..102584276,+!p1@NR4A3!1.63!90.51!NR4A3;;chr2:61108808..61108821,+!p3@REL!1.63!52.22!REL;;chr13:41635029..41635044,-!p4@ELF1!1.62!83.23!ELF1;;chr8:81397820..81397836,+!p2@ZBTB10!1.62!50.00!ZBTB10;;chr21:30672433..30672464,+!p6@BACH1!1.61!39.87!BACH1;;chr1:157108130..157108173,-!p1@ETV3!1.60!267.09!ETV3;;chr11:47400045..47400060,-!p6@SPI1!1.60!38.92!SPI1;;chr1:212782094..212782109,+!p1@ATF3!1.59!980.40!ATF3;;chr6:126240442..126240459,+!p4@NCOA7!1.59!48.42!NCOA7;;chr6:144385698..144385742,-!p2@PLAGL1!1.59!45.25!PLAGL1;;chr13:41593425..41593480,-!p1@ELF1!1.58!225.00!ELF1;;chr19:36391434..36391450,-!p1@NFKBID!1.58!71.20!NFKBID;;chr10:35484053..35484076,+!p1@CREM!1.57!87.34!CREM;;chr2:231090471..231090504,+!p2@SP140!1.57!36.39!SP140;;chr6:12012249..12012266,+!p5@HIVEP1!1.56!60.76!HIVEP1;;chr6:44233252..44233296,-!p1@NFKBIE!1.55!326.59!NFKBIE;;chr4:81104895..81104920,+!p2@PRDM8!1.55!50.63!PRDM8;;chr22:38597987..38598021,+!p2@MAFF!1.54!199.69!MAFF;;chr2:231084639..231084654,-!p2@SP110!1.54!55.06!SP110;;chr19:50432132..50432217,+!p2@ATF5!1.54!39.56!ATF5;;chr9:129567282..129567353,+!p1@ZBTB43!1.53!412.03!ZBTB43;;chr14:35872962..35873025,-!p3@NFKBIA!1.53!80.38!NFKBIA;;chr9:102584159..102584174,+!p2@NR4A3!1.53!58.23!NR4A3;;chr10:104155680..104155687,+!p6@NFKB2!1.52!31.96!NFKB2;;chr4:103446567..103446592,+!p15@NFKB1!1.50!30.70!NFKB1;;chr4:103423079..103423112,+!p4@NFKB1!1.50!30.38!NFKB1;;chr4:106068026..106068084,+!p1@TET2!1.47!248.11!TET2;;chr9:102584128..102584144,+!p3@NR4A3!1.47!53.80!NR4A3;;chr2:61108771..61108789,+!p4@REL!1.47!43.04!REL;;chr2:231090433..231090469,+!p1@SP140!1.47!28.80!SP140;;chr2:145277882..145277967,-!p3@ZEB2!1.46!46.84!ZEB2;;chr4:103446513..103446530,+!p19@NFKB1!1.46!27.85!NFKB1;;chr6:391743..391759,+!p1@IRF4!1.44!26.27!IRF4;;chr5:131826457..131826514,-!p1@IRF1!1.43!979.13!IRF1;;chr7:17338266..17338282,+!p1@AHR!1.43!267.09!AHR;;chr6:15246200..15246214,+!p2@JARID2!1.43!70.25!JARID2;;chr6:126240463..126240489,+!p6@NCOA7!1.43!28.80!NCOA7;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.43!25.95!ZBED1;;chr2:68615031..68615055,+!p3@PLEK!1.43!25.95!PLEK;;chr11:34642612..34642646,+!p1@EHF!1.43!25.95!EHF;;chr8:22550982..22550999,-!p1@EGR3!1.42!69.62!EGR3;;chr6:12011943..12012015,+!p2@HIVEP1!1.41!76.90!HIVEP1;;chr8:81397846..81397860,+!p3@ZBTB10!1.41!31.01!ZBTB10;;chr17:40440225..40440268,+!p3@STAT5A!1.40!30.70!STAT5A;;chr17:40440359..40440386,+!p4@STAT5A!1.40!24.05!STAT5A;;chr2:97202480..97202499,+!p1@ARID5A!1.39!228.49!ARID5A;;chr20:48599506..48599526,+!p1@SNAI1!1.39!146.52!SNAI1;;chr3:39195037..39195069,-!p2@CSRNP1!1.39!142.72!CSRNP1;;chr11:47399920..47399931,-!p7@SPI1!1.39!23.42!SPI1;;chr3:170075436..170075520,+!p1@SKIL!1.38!478.81!SKIL;;chr9:110252035..110252057,-!p1@KLF4!1.38!354.44!KLF4;;chr12:11802753..11802834,+!p2@ETV6!1.38!108.86!ETV6;;chr14:35872926..35872951,-!p4@NFKBIA!1.38!31.96!NFKBIA;;chr11:65430535..65430549,-!p4@RELA!1.38!26.90!RELA;;chrX:24167086..24167111,+!p4@ZFX!1.38!23.10!ZFX;;chr7:17338324..17338341,+!p3@AHR!1.37!73.74!AHR;;chr2:73520667..73520683,-!p1@EGR4!1.37!22.47!EGR4;;chrX:129244454..129244488,-!p1@ELF4!1.36!153.48!ELF4;;chr3:12329397..12329433,+!p2@PPARG!1.36!49.05!PPARG;;chr8:53373491..53373506,-!p4@ST18!1.36!22.15!ST18;;chr12:54778351..54778378,-!p6@ZNF385A!1.36!21.84!ZNF385A;;chr12:96588219..96588263,+!p2@ELK3!1.35!150.32!ELK3;;chr19:45252008..45252024,+!p2@BCL3!1.35!69.31!BCL3;;chr21:36260295..36260310,-!p3@RUNX1!1.35!34.18!RUNX1;;chr6:126240356..126240379,+!p7@NCOA7!1.34!25.32!NCOA7;;chr21:40177845..40177863,+!p1@ETS2!1.33!1162.68!ETS2;;chr12:48298765..48298783,-!p2@VDR!1.33!42.09!VDR;;chr2:145275228..145275241,-!p11@ZEB2!1.33!24.37!ZEB2;;chr17:38497662..38497713,+!p4@RARA!1.33!23.42!RARA;;chr11:615570..615721,-!p2@IRF7!1.31!37.98!IRF7;;chr8:72755345..72755349,-!p14@MSC!1.31!19.62!MSC;;chr12:72056706..72056717,+!p10@THAP2!1.31!19.30!THAP2;;chr2:191885737..191885750,-!p4@STAT1!1.31!19.30!STAT1;;chr7:106809470..106809481,+!p2@HBP1!1.30!26.58!HBP1;;chr4:83822199..83822239,+!p2@THAP9!1.30!22.47!THAP9;;chr10:3827371..3827386,-!p2@KLF6!1.29!153.48!KLF6;;chrX:153305741..153305753,-!p4@MECP2!1.29!18.67!MECP2;;chr20:56195474..56195506,-!p1@ZBP1!1.29!18.67!ZBP1;;chr12:52445218..52445237,+!p1@NR4A1!1.28!222.79!NR4A1;;chr3:37217736..37217753,-!p2@LRRFIP2!1.28!73.74!LRRFIP2;;chr2:238600998..238601013,+!p5@LRRFIP1!1.28!18.04!LRRFIP1;;chr6:106535598..106535637,+!p7@PRDM1!1.28!18.04!PRDM1;;chr8:72755203..72755239,-!p10@MSC!1.28!18.04!MSC;;chr6:143266297..143266356,-!p1@HIVEP2!1.27!83.86!HIVEP2;;chr8:72756063..72756125,-!p1@MSC!1.27!35.13!MSC;;chr2:208394817..208394834,+!p3@CREB1!1.26!68.36!CREB1;;chr4:81104985..81105005,+!p4@PRDM8!1.26!20.57!PRDM8;;chr14:35872414..35872425,-!p7@NFKBIA!1.26!18.99!NFKBIA;;chr14:35872542..35872553,-!p10@NFKBIA!1.26!17.41!NFKBIA;;chr2:68615096..68615115,+!p5@PLEK!1.26!17.41!PLEK;;chr5:88178983..88179012,-!p1@MEF2C!1.25!126.27!MEF2C;;chr10:114709999..114710031,+!p1@TCF7L2!1.24!378.81!TCF7L2;;chr16:69599899..69599919,+!p2@NFAT5!1.24!182.92!NFAT5;;chr1:161736038..161736056,+!p4@ATF6!1.24!38.29!ATF6;;chrX:153305962..153305995,-!p5@MECP2!1.24!16.46!MECP2;;chr1:158979872..158979898,+!p3@IFI16!1.23!48.42!IFI16;;chr19:45251395..45251432,+!p8@BCL3!1.23!15.82!BCL3;;chr10:104154415..104154434,+!p5@NFKB2!1.23!15.82!NFKB2;;chr2:185463247..185463263,+!p1@ZNF804A!1.22!27.53!ZNF804A;;chr2:28618532..28618610,+!p4@FOSL2!1.22!26.58!FOSL2;;chr14:75745523..75745537,+!p1@FOS!1.21!1793.71!FOS;;chr21:40177892..40177903,+!p2@ETS2!1.21!60.13!ETS2;;chr1:25256756..25256774,-!p1@RUNX3!1.21!28.17!RUNX3;;chr18:3449586..3449617,+!p8@TGIF1!1.21!24.05!TGIF1;;chr2:70167296..70167306,+!p3@MXD1!1.21!23.10!MXD1;;chr2:238600933..238600985,+!p3@LRRFIP1!1.20!79.12!LRRFIP1;;chr10:35416142..35416169,+!p3@CREM!1.20!38.61!CREM;;chr1:158985493..158985535,+!p4@IFI16!1.19!21.84!IFI16;;chr11:64764435..64764449,-!p1@BATF2!1.19!19.94!BATF2;;chr2:191878812..191878823,-!p2@STAT1!1.19!18.35!STAT1;;chr4:106066712..106066728,+!p8@TET2!1.19!14.56!TET2;;chr20:47894569..47894799,-!p1@ZNFX1!1.18!371.84!ZNFX1;;chr12:96588279..96588299,+!p4@ELK3!1.18!66.77!ELK3;;chr10:104155455..104155479,+!p1@NFKB2!1.17!197.47!NFKB2;;chr2:70142189..70142223,+!p2@MXD1!1.17!97.79!MXD1;;chr1:38325256..38325280,-!p1@MTF1!1.17!84.50!MTF1;;chr19:47616992..47617011,-!p4@ZC3H4!1.17!29.11!ZC3H4;;chr18:3449618..3449634,+!p13@TGIF1!1.17!17.09!TGIF1;;chr2:157189180..157189290,-!p1@NR4A2!1.16!69.31!NR4A2;;chr2:178129358..178129403,-!p5@NFE2L2!1.16!53.48!NFE2L2;;chr8:72756267..72756296,-!p4@MSC!1.16!19.94!MSC;;chr21:30672734..30672748,+!p11@BACH1!1.16!13.61!BACH1;;chr13:41593392..41593403,-!p7@ELF1!1.16!13.61!ELF1;;chr14:24630465..24630531,+!p1@IRF9!1.15!497.48!IRF9;;chr18:3449720..3449749,+!p2@TGIF1!1.15!27.85!TGIF1;;chr8:81397876..81397898,+!p5@ZBTB10!1.15!15.51!ZBTB10;;chr2:192015677..192015691,-!p3@STAT4!1.15!12.97!STAT4;;chr20:48807351..48807384,+!p1@CEBPB!1.14!1305.41!CEBPB;;chr6:35310395..35310410,+!p2@PPARD!1.14!49.68!PPARD;;chr1:221052733..221052749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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=EFO:0000369,FF:0000335,FF:0000625,FF:0011108,FF:11885-125D4 | |fonse_treatment=EFO:0000369,FF:0000335,FF:0000625,FF:0011108,FF:11885-125D4 | ||
|fonse_treatment_closure=EFO:0000369,FF:0000335,FF:0000625,FF:0011108,FF:11885-125D4 | |fonse_treatment_closure=EFO:0000369,FF:0000335,FF:0000625,FF:0011108,FF:11885-125D4 | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520lipopolysaccharide%252c%2520donor3.CNhs13545.11885-125D4.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520lipopolysaccharide%252c%2520donor3.CNhs13545.11885-125D4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520lipopolysaccharide%252c%2520donor3.CNhs13545.11885-125D4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520lipopolysaccharide%252c%2520donor3.CNhs13545.11885-125D4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520lipopolysaccharide%252c%2520donor3.CNhs13545.11885-125D4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11885-125D4 | |||
|is_a=EFO:0002091;;FF:0011108 | |||
|is_obsolete= | |||
|library_id=CNhs13545 | |||
|library_id_phase_based=2:CNhs13545 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11885 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11885 | |||
|name=CD14+ monocytes - treated with lipopolysaccharide, donor3 | |||
|namespace= | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13545,LSID1029,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0.119408455420648,0.562611007041395,0.0896470922062728,0,0,0.585253288788725,0.38766566454118,0.119408455420648,0.403657255176754,0.0273843316528144,0,0,0,0,0,0,0,0,0,0.212966178241721,0.619575784459513,0.355231069747725,0,-0.153323010348428,0,0,0,0.582293635833835,0,-0.0979578962680575,0,0.65306511026197,-0.132956589778862,0,0,0,0.119408455420648,0,0,0,0.782716090414288,0,0.119408455420648,0,0,0.0323340560853465,0,0.119408455420648,0,0,0.23110720299032,0,0.119408455420648,0,-0.0242150211128343,0,0,0,0.119408455420648,0,-0.10345891446321,0,-0.0969923612426051,0,0.934250797369523,-0.097343627213097,0,1.07337677513781,0,0,0,0,0,0.129580538869286,0,0,1.02093574695348,0,0,0.462214405980639,0,0,0,0.119408455420648,0,0,0,0.0405517358720444,0,-0.00360896025577208,-0.552571649267773,0,0,0,0.00534452030994115,-0.211197402695869,0.106483089120861,0,1.51792455368884,0,0.257195718510019,0.112954939167148,0,0,0,0,0,1.04522511014996,0.119408455420648,0,0,0,0,0,0.529428362498944,0,0,0,0,-0.096373593922461,0.212966178241721,0,0,0.128298689055404,0.257916859122397,0.212966178241721,0.289898101694364,0.212966178241721,0,0,0 | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.37054 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D5-6 | |||
|rna_od260/230=0.96 | |||
|rna_od260/280=1.95 | |||
|rna_position=D4 | |||
|rna_rin=8.9 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125D4 | |||
|rna_weight_ug=1.66743 | |||
|sample_age=21 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor3 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.75099743040971e-276!GO:0005737;cytoplasm;6.89199271806218e-126!GO:0043227;membrane-bound organelle;1.84289707022382e-111!GO:0043231;intracellular membrane-bound organelle;3.79656977891567e-111!GO:0043226;organelle;9.0931700213276e-104!GO:0043229;intracellular organelle;5.28190823112755e-103!GO:0044444;cytoplasmic part;2.16065717909319e-80!GO:0005515;protein binding;3.08353260597541e-72!GO:0044422;organelle part;5.88509441157675e-69!GO:0044446;intracellular organelle part;2.07550294701376e-67!GO:0044237;cellular metabolic process;3.47831879027414e-64!GO:0044238;primary metabolic process;7.69889975445207e-63!GO:0032991;macromolecular complex;5.43100941255027e-61!GO:0043170;macromolecule metabolic process;3.30992425117298e-60!GO:0003723;RNA binding;1.56333394606631e-57!GO:0030529;ribonucleoprotein complex;8.48662505992929e-54!GO:0044428;nuclear part;1.1364417380393e-47!GO:0019538;protein metabolic process;3.74480781380204e-47!GO:0005634;nucleus;4.33366023382931e-45!GO:0006412;translation;8.16808008710051e-45!GO:0044267;cellular protein metabolic process;7.18020658824753e-44!GO:0044260;cellular macromolecule metabolic process;1.59656961374957e-43!GO:0033036;macromolecule localization;9.99014554961315e-42!GO:0015031;protein transport;1.81957453785927e-40!GO:0045184;establishment of protein localization;1.96042573966309e-40!GO:0043233;organelle lumen;2.36772577935358e-39!GO:0031974;membrane-enclosed lumen;2.36772577935358e-39!GO:0008104;protein localization;9.76731540101804e-39!GO:0005829;cytosol;7.37069407285023e-37!GO:0006915;apoptosis;1.3714292297033e-35!GO:0012501;programmed cell death;1.83741316711584e-35!GO:0008219;cell death;2.34699634110783e-33!GO:0016265;death;2.34699634110783e-33!GO:0009059;macromolecule biosynthetic process;6.93272966357427e-33!GO:0016071;mRNA metabolic process;3.05991514150063e-32!GO:0006396;RNA processing;3.30933450515949e-32!GO:0044249;cellular biosynthetic process;4.54445190068989e-32!GO:0009058;biosynthetic process;4.54445190068989e-32!GO:0043283;biopolymer metabolic process;5.61144522496275e-32!GO:0010467;gene expression;3.54597544609271e-31!GO:0031090;organelle membrane;5.42308142923848e-31!GO:0043234;protein complex;1.03873937539256e-30!GO:0031981;nuclear lumen;5.51703240744713e-30!GO:0005840;ribosome;1.68386630313471e-28!GO:0008380;RNA splicing;3.20043695369812e-28!GO:0005739;mitochondrion;3.20043695369812e-28!GO:0006886;intracellular protein transport;1.05489416237704e-27!GO:0046907;intracellular transport;1.76934849272379e-27!GO:0006397;mRNA processing;2.76587900802674e-27!GO:0016043;cellular component organization and biogenesis;3.39057644262049e-27!GO:0003735;structural constituent of ribosome;2.69855537170827e-26!GO:0033279;ribosomal subunit;4.31015525246846e-25!GO:0031967;organelle envelope;5.32957018360724e-25!GO:0031975;envelope;1.0115736372943e-24!GO:0005830;cytosolic ribosome (sensu Eukaryota);5.08062802334819e-24!GO:0042981;regulation of apoptosis;2.10503588002875e-23!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.44323731240866e-23!GO:0043067;regulation of programmed cell death;5.55090608754398e-23!GO:0044445;cytosolic part;1.27120006074745e-22!GO:0005681;spliceosome;1.06354994916306e-21!GO:0051649;establishment of cellular localization;1.22723324874437e-21!GO:0065003;macromolecular complex assembly;1.81152006499618e-21!GO:0000166;nucleotide binding;4.47892068965444e-21!GO:0051641;cellular localization;5.43701693774225e-21!GO:0002376;immune system process;7.47066545722821e-21!GO:0044429;mitochondrial part;8.16322582225906e-21!GO:0005654;nucleoplasm;1.32743853794639e-20!GO:0008134;transcription factor binding;6.67040255835572e-20!GO:0007243;protein kinase cascade;8.45461821857349e-20!GO:0022607;cellular component assembly;1.00918640495626e-17!GO:0006955;immune response;2.34144146143567e-17!GO:0048523;negative regulation of cellular process;3.68798582386157e-17!GO:0044265;cellular macromolecule catabolic process;4.0899948801315e-17!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.76840475588645e-17!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;5.92743253337917e-17!GO:0016462;pyrophosphatase activity;6.14559395640728e-17!GO:0006119;oxidative phosphorylation;6.8591077047028e-17!GO:0016817;hydrolase activity, acting on acid anhydrides;8.72682874301075e-17!GO:0044451;nucleoplasm part;8.7675963721503e-17!GO:0017111;nucleoside-triphosphatase activity;1.26890321690521e-16!GO:0006512;ubiquitin cycle;1.30552142089327e-16!GO:0043285;biopolymer catabolic process;1.97766653931747e-16!GO:0016192;vesicle-mediated transport;2.10900407439219e-16!GO:0007249;I-kappaB kinase/NF-kappaB cascade;2.39324944991482e-16!GO:0048770;pigment granule;3.63515551527513e-16!GO:0042470;melanosome;3.63515551527513e-16!GO:0005740;mitochondrial envelope;1.90380430097507e-15!GO:0032553;ribonucleotide binding;2.060250299225e-15!GO:0032555;purine ribonucleotide binding;2.060250299225e-15!GO:0048519;negative regulation of biological process;2.40396408849294e-15!GO:0009057;macromolecule catabolic process;4.12244456824143e-15!GO:0031966;mitochondrial membrane;4.43218093132337e-15!GO:0006605;protein targeting;5.0091738249592e-15!GO:0017076;purine nucleotide binding;5.37205502995306e-15!GO:0043412;biopolymer modification;6.7821982860817e-15!GO:0009615;response to virus;9.06493625270372e-15!GO:0007242;intracellular signaling cascade;9.28042223617886e-15!GO:0022618;protein-RNA complex assembly;9.89836670993534e-15!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.24748367553173e-14!GO:0019866;organelle inner membrane;2.27666153350638e-14!GO:0019941;modification-dependent protein catabolic process;2.70621090892397e-14!GO:0043632;modification-dependent macromolecule catabolic process;2.70621090892397e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;3.54517027120455e-14!GO:0044257;cellular protein catabolic process;4.7906907103769e-14!GO:0043069;negative regulation of programmed cell death;5.50445781928167e-14!GO:0006511;ubiquitin-dependent protein catabolic process;6.54985927246789e-14!GO:0005773;vacuole;6.81622015020051e-14!GO:0043066;negative regulation of apoptosis;6.94531546709057e-14!GO:0006950;response to stress;8.00924807116984e-14!GO:0006464;protein modification process;9.27786093801975e-14!GO:0016604;nuclear body;1.29197483670332e-13!GO:0050794;regulation of cellular process;1.69294623946527e-13!GO:0015934;large ribosomal subunit;1.79050096506546e-13!GO:0043687;post-translational protein modification;1.92298932633565e-13!GO:0000502;proteasome complex (sensu Eukaryota);2.04217136961455e-13!GO:0003676;nucleic acid binding;2.05173113438352e-13!GO:0051246;regulation of protein metabolic process;2.189099832546e-13!GO:0044248;cellular catabolic process;2.23040982927111e-13!GO:0048522;positive regulation of cellular process;3.16275377809888e-13!GO:0006913;nucleocytoplasmic transport;3.85146463694234e-13!GO:0016874;ligase activity;5.71484693256857e-13!GO:0051169;nuclear transport;6.98712203896716e-13!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;7.58164017074667e-13!GO:0006996;organelle organization and biogenesis;7.66228419333905e-13!GO:0030163;protein catabolic process;8.79190628839152e-13!GO:0065009;regulation of a molecular function;9.57581589389013e-13!GO:0015935;small ribosomal subunit;9.82428009698602e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.28804670398959e-12!GO:0016070;RNA metabolic process;1.60958541264939e-12!GO:0008135;translation factor activity, nucleic acid binding;2.97571496583489e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);3.0115207223994e-12!GO:0000323;lytic vacuole;3.33655522148269e-12!GO:0005764;lysosome;3.33655522148269e-12!GO:0003712;transcription cofactor activity;4.35357006067982e-12!GO:0016607;nuclear speck;4.72625563333832e-12!GO:0044455;mitochondrial membrane part;4.9051373029253e-12!GO:0048518;positive regulation of biological process;5.69526387549947e-12!GO:0006793;phosphorus metabolic process;6.40616195360468e-12!GO:0006796;phosphate metabolic process;6.40616195360468e-12!GO:0009607;response to biotic stimulus;7.11808664995862e-12!GO:0005743;mitochondrial inner membrane;8.47188629162513e-12!GO:0005768;endosome;1.14004577039979e-11!GO:0006916;anti-apoptosis;1.25301665334983e-11!GO:0006457;protein folding;1.706003724481e-11!GO:0012505;endomembrane system;2.8648355041796e-11!GO:0009967;positive regulation of signal transduction;3.4539690099537e-11!GO:0006259;DNA metabolic process;3.91980151537997e-11!GO:0003743;translation initiation factor activity;4.17405098822763e-11!GO:0006366;transcription from RNA polymerase II promoter;5.0719378859436e-11!GO:0005794;Golgi apparatus;9.14543294452424e-11!GO:0006417;regulation of translation;1.00567955597038e-10!GO:0016787;hydrolase activity;1.03660392908232e-10!GO:0050789;regulation of biological process;1.05859187858247e-10!GO:0043065;positive regulation of apoptosis;1.33857315663646e-10!GO:0051186;cofactor metabolic process;1.50511157594104e-10!GO:0006413;translational initiation;1.61139552760079e-10!GO:0016310;phosphorylation;2.22424532194153e-10!GO:0005524;ATP binding;2.37558814175587e-10!GO:0043068;positive regulation of programmed cell death;2.53398808434859e-10!GO:0032559;adenyl ribonucleotide binding;2.87825310048663e-10!GO:0005730;nucleolus;3.07128614662525e-10!GO:0048468;cell development;3.90344436954874e-10!GO:0051082;unfolded protein binding;6.78294169343914e-10!GO:0005635;nuclear envelope;6.83962112504455e-10!GO:0030554;adenyl nucleotide binding;7.36060378646444e-10!GO:0006446;regulation of translational initiation;9.26715112484247e-10!GO:0005746;mitochondrial respiratory chain;1.05716184928105e-09!GO:0006732;coenzyme metabolic process;1.34065268871282e-09!GO:0008639;small protein conjugating enzyme activity;1.74545095485995e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.75836699984889e-09!GO:0009889;regulation of biosynthetic process;1.86739670643819e-09!GO:0065007;biological regulation;1.92304695264028e-09!GO:0004842;ubiquitin-protein ligase activity;2.38256957748933e-09!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.60702586270969e-09!GO:0050790;regulation of catalytic activity;2.63002290485987e-09!GO:0009056;catabolic process;2.93353281244852e-09!GO:0017038;protein import;3.02148930902744e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;3.31145979124506e-09!GO:0000375;RNA splicing, via transesterification reactions;3.31145979124506e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.31145979124506e-09!GO:0019787;small conjugating protein ligase activity;3.73096381149941e-09!GO:0051726;regulation of cell cycle;4.58423957968936e-09!GO:0000074;regulation of progression through cell cycle;4.63572034792111e-09!GO:0050136;NADH dehydrogenase (quinone) activity;4.63572034792111e-09!GO:0003954;NADH dehydrogenase activity;4.63572034792111e-09!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.63572034792111e-09!GO:0007049;cell cycle;4.926341104293e-09!GO:0031326;regulation of cellular biosynthetic process;4.9399369585097e-09!GO:0006917;induction of apoptosis;5.41992561251072e-09!GO:0031324;negative regulation of cellular metabolic process;5.95560819480238e-09!GO:0006164;purine nucleotide biosynthetic process;6.32077520309141e-09!GO:0006163;purine nucleotide metabolic process;6.34087093224365e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;6.34087093224365e-09!GO:0019829;cation-transporting ATPase activity;6.34087093224365e-09!GO:0015986;ATP synthesis coupled proton transport;9.52875959133133e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;9.52875959133133e-09!GO:0012502;induction of programmed cell death;9.52875959133133e-09!GO:0009152;purine ribonucleotide biosynthetic process;1.54716055083113e-08!GO:0009150;purine ribonucleotide metabolic process;1.63961827000424e-08!GO:0016887;ATPase activity;1.75249352637841e-08!GO:0042623;ATPase activity, coupled;1.8248102762968e-08!GO:0009259;ribonucleotide metabolic process;2.00942355090735e-08!GO:0051170;nuclear import;2.2276391526175e-08!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.63632577385365e-08!GO:0009055;electron carrier activity;2.71885951548995e-08!GO:0005770;late endosome;3.41077791429709e-08!GO:0031965;nuclear membrane;3.74522552917527e-08!GO:0044453;nuclear membrane part;4.06565397925916e-08!GO:0005525;GTP binding;4.4406321685511e-08!GO:0009260;ribonucleotide biosynthetic process;4.4406321685511e-08!GO:0006606;protein import into nucleus;5.50190631614213e-08!GO:0005783;endoplasmic reticulum;5.75629766823228e-08!GO:0048193;Golgi vesicle transport;6.27157547851787e-08!GO:0042775;organelle ATP synthesis coupled electron transport;7.16201591224813e-08!GO:0042773;ATP synthesis coupled electron transport;7.16201591224813e-08!GO:0043228;non-membrane-bound organelle;7.27654796928883e-08!GO:0043232;intracellular non-membrane-bound organelle;7.27654796928883e-08!GO:0006754;ATP biosynthetic process;9.51111449975962e-08!GO:0006753;nucleoside phosphate metabolic process;9.51111449975962e-08!GO:0016564;transcription repressor activity;9.72213239847511e-08!GO:0003924;GTPase activity;1.06895286108784e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.21255087426949e-07!GO:0045786;negative regulation of progression through cell cycle;1.30546515628181e-07!GO:0030964;NADH dehydrogenase complex (quinone);1.59565927761921e-07!GO:0045271;respiratory chain complex I;1.59565927761921e-07!GO:0005747;mitochondrial respiratory chain complex I;1.59565927761921e-07!GO:0009892;negative regulation of metabolic process;1.65609368110862e-07!GO:0009108;coenzyme biosynthetic process;1.91046915351894e-07!GO:0051188;cofactor biosynthetic process;1.94541266049779e-07!GO:0004386;helicase activity;2.43323593661453e-07!GO:0050657;nucleic acid transport;2.65271639616579e-07!GO:0051236;establishment of RNA localization;2.65271639616579e-07!GO:0050658;RNA transport;2.65271639616579e-07!GO:0019899;enzyme binding;2.81311418322339e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.83947563652828e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.29947436357931e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.29947436357931e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.41103683937028e-07!GO:0016469;proton-transporting two-sector ATPase complex;3.6100180567205e-07!GO:0006403;RNA localization;4.03901152295668e-07!GO:0046034;ATP metabolic process;4.08931823231571e-07!GO:0003713;transcription coactivator activity;4.15054743161372e-07!GO:0009142;nucleoside triphosphate biosynthetic process;4.15054743161372e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.15054743161372e-07!GO:0016881;acid-amino acid ligase activity;4.21001301973366e-07!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.2408623687037e-07!GO:0005774;vacuolar membrane;5.53334246708509e-07!GO:0009966;regulation of signal transduction;5.71049564190019e-07!GO:0008026;ATP-dependent helicase activity;5.76944944342095e-07!GO:0031980;mitochondrial lumen;5.78030355514329e-07!GO:0005759;mitochondrial matrix;5.78030355514329e-07!GO:0006954;inflammatory response;6.23488148871498e-07!GO:0008565;protein transporter activity;6.58665518254948e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;7.03846694702103e-07!GO:0009144;purine nucleoside triphosphate metabolic process;7.03846694702103e-07!GO:0006461;protein complex assembly;7.80090132008411e-07!GO:0006752;group transfer coenzyme metabolic process;8.3442472518199e-07!GO:0009199;ribonucleoside triphosphate metabolic process;8.37679112330798e-07!GO:0007264;small GTPase mediated signal transduction;9.31818563987478e-07!GO:0032561;guanyl ribonucleotide binding;9.75541402573559e-07!GO:0019001;guanyl nucleotide binding;9.75541402573559e-07!GO:0051707;response to other organism;1.22711569207856e-06!GO:0008047;enzyme activator activity;1.38065917153704e-06!GO:0045321;leukocyte activation;1.44010025425606e-06!GO:0016044;membrane organization and biogenesis;1.47819756608761e-06!GO:0005643;nuclear pore;1.62851580990061e-06!GO:0044440;endosomal part;1.73183763729429e-06!GO:0010008;endosome membrane;1.73183763729429e-06!GO:0022402;cell cycle process;1.85458966818752e-06!GO:0006974;response to DNA damage stimulus;2.09244942628655e-06!GO:0005839;proteasome core complex (sensu Eukaryota);2.09244942628655e-06!GO:0009141;nucleoside triphosphate metabolic process;2.09244942628655e-06!GO:0001816;cytokine production;2.10768189413289e-06!GO:0016481;negative regulation of transcription;2.13025805578347e-06!GO:0044437;vacuolar part;2.47984088532787e-06!GO:0006952;defense response;2.89916292136719e-06!GO:0005793;ER-Golgi intermediate compartment;3.00979182987302e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;3.1471079853131e-06!GO:0051028;mRNA transport;3.22361613468175e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;3.63868773812947e-06!GO:0005765;lysosomal membrane;4.12072806015568e-06!GO:0044432;endoplasmic reticulum part;4.66464316588402e-06!GO:0019222;regulation of metabolic process;5.11685515580637e-06!GO:0004298;threonine endopeptidase activity;5.50939068144098e-06!GO:0051789;response to protein stimulus;5.56766044398401e-06!GO:0006986;response to unfolded protein;5.56766044398401e-06!GO:0032446;protein modification by small protein conjugation;7.43380672418673e-06!GO:0006325;establishment and/or maintenance of chromatin architecture;8.13134430163374e-06!GO:0008632;apoptotic program;1.00105787332312e-05!GO:0016563;transcription activator activity;1.00894747933898e-05!GO:0016567;protein ubiquitination;1.20556348598132e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.21353013515764e-05!GO:0003714;transcription corepressor activity;1.28064228385189e-05!GO:0006401;RNA catabolic process;1.50440947406325e-05!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.51506316473961e-05!GO:0031982;vesicle;1.51851115462277e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.52527696842834e-05!GO:0015399;primary active transmembrane transporter activity;1.52527696842834e-05!GO:0051338;regulation of transferase activity;1.55531404810035e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.70771485767151e-05!GO:0016197;endosome transport;1.72868408534798e-05!GO:0006323;DNA packaging;1.83105829599487e-05!GO:0030099;myeloid cell differentiation;1.84196892892899e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.09726513133255e-05!GO:0065002;intracellular protein transport across a membrane;2.1571109770619e-05!GO:0030097;hemopoiesis;2.26387632925891e-05!GO:0043549;regulation of kinase activity;2.48332005608197e-05!GO:0043566;structure-specific DNA binding;2.67370272908539e-05!GO:0046649;lymphocyte activation;2.84882989526647e-05!GO:0046930;pore complex;2.93096045792287e-05!GO:0009893;positive regulation of metabolic process;2.98453084699405e-05!GO:0031252;leading edge;3.03076483642079e-05!GO:0006281;DNA repair;3.34200246693282e-05!GO:0003724;RNA helicase activity;3.7980092567226e-05!GO:0048475;coated membrane;4.20946606645098e-05!GO:0030117;membrane coat;4.20946606645098e-05!GO:0045859;regulation of protein kinase activity;4.22753878738338e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;4.44182757713007e-05!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.94999867768774e-05!GO:0006888;ER to Golgi vesicle-mediated transport;5.1508152879713e-05!GO:0005769;early endosome;5.33433006596412e-05!GO:0006402;mRNA catabolic process;6.86538411277424e-05!GO:0001775;cell activation;7.09676066317479e-05!GO:0006613;cotranslational protein targeting to membrane;7.22902220099509e-05!GO:0005789;endoplasmic reticulum membrane;7.37191567915159e-05!GO:0007050;cell cycle arrest;7.8584933320628e-05!GO:0030120;vesicle coat;8.32309034218997e-05!GO:0030662;coated vesicle membrane;8.32309034218997e-05!GO:0031410;cytoplasmic vesicle;8.65534527717612e-05!GO:0016568;chromatin modification;9.8829595366093e-05!GO:0006897;endocytosis;0.000102574428999915!GO:0010324;membrane invagination;0.000102574428999915!GO:0042110;T cell activation;0.000102574428999915!GO:0051168;nuclear export;0.00010380855109793!GO:0003697;single-stranded DNA binding;0.000105130815651162!GO:0031988;membrane-bound vesicle;0.000115582968571492!GO:0009060;aerobic respiration;0.000117732465575835!GO:0031902;late endosome membrane;0.000119510019720711!GO:0008234;cysteine-type peptidase activity;0.000121262946419661!GO:0045259;proton-transporting ATP synthase complex;0.000127489558417789!GO:0051336;regulation of hydrolase activity;0.000130427921945462!GO:0005761;mitochondrial ribosome;0.000139286703908915!GO:0000313;organellar ribosome;0.000139286703908915!GO:0009117;nucleotide metabolic process;0.000142671438203033!GO:0002521;leukocyte differentiation;0.000154812762366426!GO:0051276;chromosome organization and biogenesis;0.00016452636079893!GO:0030532;small nuclear ribonucleoprotein complex;0.00016452636079893!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000180215636742253!GO:0042254;ribosome biogenesis and assembly;0.000181960390510687!GO:0022890;inorganic cation transmembrane transporter activity;0.000182846495576502!GO:0046822;regulation of nucleocytoplasmic transport;0.00024431114552188!GO:0043492;ATPase activity, coupled to movement of substances;0.000249721128463003!GO:0030695;GTPase regulator activity;0.000252734190415102!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000266411252296237!GO:0016740;transferase activity;0.00027832390511862!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000313004306113498!GO:0005885;Arp2/3 protein complex;0.000316634909021141!GO:0007041;lysosomal transport;0.00032049757376899!GO:0022415;viral reproductive process;0.000327080289113376!GO:0007005;mitochondrion organization and biogenesis;0.000327195339059327!GO:0009719;response to endogenous stimulus;0.000327195339059327!GO:0051427;hormone receptor binding;0.000330426743120967!GO:0007034;vacuolar transport;0.00034187225890816!GO:0016023;cytoplasmic membrane-bound vesicle;0.000354595135299521!GO:0009611;response to wounding;0.000363402722594326!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000372586630017187!GO:0051223;regulation of protein transport;0.000378547339363521!GO:0031325;positive regulation of cellular metabolic process;0.000388607214787832!GO:0007259;JAK-STAT cascade;0.000388948990281532!GO:0031323;regulation of cellular metabolic process;0.000395417029805426!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000405223273247123!GO:0006818;hydrogen transport;0.000408229373838362!GO:0000245;spliceosome assembly;0.000426122259663902!GO:0002520;immune system development;0.000426122259663902!GO:0045941;positive regulation of transcription;0.000426226375658986!GO:0046519;sphingoid metabolic process;0.000436907965196403!GO:0046983;protein dimerization activity;0.00045387270292298!GO:0006612;protein targeting to membrane;0.000463632543585429!GO:0008654;phospholipid biosynthetic process;0.000466944165290983!GO:0015992;proton transport;0.000475112852715278!GO:0005096;GTPase activator activity;0.000475112852715278!GO:0035257;nuclear hormone receptor binding;0.000491312042393059!GO:0008186;RNA-dependent ATPase activity;0.000508874899869005!GO:0006672;ceramide metabolic process;0.000510913159932435!GO:0048534;hemopoietic or lymphoid organ development;0.000581628494052731!GO:0045333;cellular respiration;0.000581628494052731!GO:0045893;positive regulation of transcription, DNA-dependent;0.000589315534047121!GO:0006399;tRNA metabolic process;0.000611529518594757!GO:0005057;receptor signaling protein activity;0.000615125623381175!GO:0032940;secretion by cell;0.000691260731789259!GO:0002757;immune response-activating signal transduction;0.000694991745923117!GO:0004674;protein serine/threonine kinase activity;0.000703950213589039!GO:0065004;protein-DNA complex assembly;0.000737875981873103!GO:0001726;ruffle;0.000759274456723718!GO:0019221;cytokine and chemokine mediated signaling pathway;0.000847253087220486!GO:0016779;nucleotidyltransferase activity;0.00100248008109163!GO:0006919;caspase activation;0.00102640917199038!GO:0043281;regulation of caspase activity;0.00103152942259482!GO:0044431;Golgi apparatus part;0.00105762351529177!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00107798697749579!GO:0051090;regulation of transcription factor activity;0.00111772832760388!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.00115908125812157!GO:0004812;aminoacyl-tRNA ligase activity;0.00115908125812157!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.00115908125812157!GO:0045637;regulation of myeloid cell differentiation;0.00117903504890529!GO:0043085;positive regulation of catalytic activity;0.00118315175706573!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0012574967822297!GO:0033157;regulation of intracellular protein transport;0.00137431554574859!GO:0042306;regulation of protein import into nucleus;0.00137431554574859!GO:0004004;ATP-dependent RNA helicase activity;0.00143815814862376!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.00145869523239263!GO:0005741;mitochondrial outer membrane;0.00146409411759394!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00159972364412858!GO:0005083;small GTPase regulator activity;0.0016027508249565!GO:0043280;positive regulation of caspase activity;0.00161617530970436!GO:0009165;nucleotide biosynthetic process;0.00164002304931309!GO:0043623;cellular protein complex assembly;0.00164260211942614!GO:0002764;immune response-regulating signal transduction;0.00164260211942614!GO:0007033;vacuole organization and biogenesis;0.00169236408086643!GO:0018193;peptidyl-amino acid modification;0.00171193322295801!GO:0043038;amino acid activation;0.00171970626439432!GO:0006418;tRNA aminoacylation for protein translation;0.00171970626439432!GO:0043039;tRNA aminoacylation;0.00171970626439432!GO:0006643;membrane lipid metabolic process;0.00178874877295021!GO:0045892;negative regulation of transcription, DNA-dependent;0.00181594178635264!GO:0051187;cofactor catabolic process;0.00189973634437302!GO:0005667;transcription factor complex;0.00192218034953762!GO:0001819;positive regulation of cytokine production;0.00195849118247468!GO:0030036;actin cytoskeleton organization and biogenesis;0.0019979194958189!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0019998658468317!GO:0001817;regulation of cytokine production;0.00203642771893742!GO:0002252;immune effector process;0.00208876580302021!GO:0005637;nuclear inner membrane;0.00208959974205136!GO:0005798;Golgi-associated vesicle;0.00209199164306285!GO:0006091;generation of precursor metabolites and energy;0.00209199164306285!GO:0016251;general RNA polymerase II transcription factor activity;0.00214028811596035!GO:0060090;molecular adaptor activity;0.0022327505666189!GO:0003729;mRNA binding;0.00237473585352119!GO:0000151;ubiquitin ligase complex;0.00247366654377141!GO:0007040;lysosome organization and biogenesis;0.00247782102101688!GO:0051059;NF-kappaB binding;0.00250216670411202!GO:0004197;cysteine-type endopeptidase activity;0.00256410012930454!GO:0030149;sphingolipid catabolic process;0.00272457562183812!GO:0006099;tricarboxylic acid cycle;0.002806349312229!GO:0046356;acetyl-CoA catabolic process;0.002806349312229!GO:0002274;myeloid leukocyte activation;0.00281921103128954!GO:0007265;Ras protein signal transduction;0.00291690063517537!GO:0019220;regulation of phosphate metabolic process;0.0029383311655792!GO:0051174;regulation of phosphorus metabolic process;0.0029383311655792!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00313916634234162!GO:0031968;organelle outer membrane;0.00324836192558114!GO:0042990;regulation of transcription factor import into nucleus;0.00344657561956841!GO:0042991;transcription factor import into nucleus;0.00344657561956841!GO:0008383;manganese superoxide dismutase activity;0.00356600199315922!GO:0001315;age-dependent response to reactive oxygen species;0.00356600199315922!GO:0002250;adaptive immune response;0.00365418973135578!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.00365418973135578!GO:0016072;rRNA metabolic process;0.00384670776757978!GO:0051247;positive regulation of protein metabolic process;0.00395800388761389!GO:0019867;outer membrane;0.00398526327588031!GO:0046966;thyroid hormone receptor binding;0.00408521432020236!GO:0030218;erythrocyte differentiation;0.00412150792246428!GO:0009891;positive regulation of biosynthetic process;0.00414509659620129!GO:0005813;centrosome;0.00422374309336066!GO:0033116;ER-Golgi intermediate compartment membrane;0.00442667145636391!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00456175011510072!GO:0000278;mitotic cell cycle;0.00464498580347877!GO:0010468;regulation of gene expression;0.00468458951728159!GO:0019904;protein domain specific binding;0.00477388138728181!GO:0042108;positive regulation of cytokine biosynthetic process;0.00477392771493468!GO:0031072;heat shock protein binding;0.0048821915695981!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00499780812497872!GO:0043433;negative regulation of transcription factor activity;0.00501373378319822!GO:0031901;early endosome membrane;0.00515540571735098!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00534031615991295!GO:0042802;identical protein binding;0.00534242066481785!GO:0006364;rRNA processing;0.00541387340557523!GO:0019210;kinase inhibitor activity;0.00546820231806132!GO:0004860;protein kinase inhibitor activity;0.00565266615895021!GO:0033673;negative regulation of kinase activity;0.00574678864129952!GO:0006469;negative regulation of protein kinase activity;0.00574678864129952!GO:0006084;acetyl-CoA metabolic process;0.00584450363436363!GO:0016301;kinase activity;0.00599279911863554!GO:0042107;cytokine metabolic process;0.00599279911863554!GO:0045727;positive regulation of translation;0.00616431521395932!GO:0043087;regulation of GTPase activity;0.00624819748423072!GO:0043021;ribonucleoprotein binding;0.00655431518442771!GO:0019079;viral genome replication;0.00662670851360676!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00664156367052508!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.00670372201645159!GO:0045454;cell redox homeostasis;0.00671061352019124!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00674566595645598!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00674566595645598!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00674566595645598!GO:0006935;chemotaxis;0.00723372287026172!GO:0042330;taxis;0.00723372287026172!GO:0009109;coenzyme catabolic process;0.00734551043383621!GO:0008637;apoptotic mitochondrial changes;0.0076209609023374!GO:0008283;cell proliferation;0.00762235366953236!GO:0003690;double-stranded DNA binding;0.00773218328214925!GO:0006611;protein export from nucleus;0.00780519101384852!GO:0002684;positive regulation of immune system process;0.00780519101384852!GO:0006891;intra-Golgi vesicle-mediated transport;0.00780519101384852!GO:0019058;viral infectious cycle;0.00787910175623873!GO:0016791;phosphoric monoester hydrolase activity;0.00816165413734124!GO:0045646;regulation of erythrocyte differentiation;0.00824992855830057!GO:0006333;chromatin assembly or disassembly;0.00849780200639358!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0085006208362055!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0085006208362055!GO:0032386;regulation of intracellular transport;0.0085006208362055!GO:0051348;negative regulation of transferase activity;0.00851990309733251!GO:0042089;cytokine biosynthetic process;0.00867759765691999!GO:0048500;signal recognition particle;0.00881758047996003!GO:0005099;Ras GTPase activator activity;0.0088997880018264!GO:0044262;cellular carbohydrate metabolic process;0.00892625471504356!GO:0033367;protein localization in mast cell secretory granule;0.00920921521822534!GO:0033365;protein localization in organelle;0.00920921521822534!GO:0033371;T cell secretory granule organization and biogenesis;0.00920921521822534!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.00920921521822534!GO:0033375;protease localization in T cell secretory granule;0.00920921521822534!GO:0042629;mast cell granule;0.00920921521822534!GO:0033377;maintenance of protein localization in T cell secretory granule;0.00920921521822534!GO:0033364;mast cell secretory granule organization and biogenesis;0.00920921521822534!GO:0033380;granzyme B localization in T cell secretory granule;0.00920921521822534!GO:0033379;maintenance of protease localization in T cell secretory granule;0.00920921521822534!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.00920921521822534!GO:0033368;protease localization in mast cell secretory granule;0.00920921521822534!GO:0033366;protein localization in secretory granule;0.00920921521822534!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.00920921521822534!GO:0033374;protein localization in T cell secretory granule;0.00920921521822534!GO:0042221;response to chemical stimulus;0.0092839006721639!GO:0002682;regulation of immune system process;0.0096602381230106!GO:0048487;beta-tubulin binding;0.0104877218887528!GO:0051098;regulation of binding;0.0107312684192258!GO:0051251;positive regulation of lymphocyte activation;0.0109078377244957!GO:0000139;Golgi membrane;0.010987310217609!GO:0050778;positive regulation of immune response;0.0114810602914542!GO:0005152;interleukin-1 receptor antagonist activity;0.0119304847783226!GO:0030353;fibroblast growth factor receptor antagonist activity;0.0119304847783226!GO:0048872;homeostasis of number of cells;0.0119304847783226!GO:0006468;protein amino acid phosphorylation;0.0122155845564533!GO:0003725;double-stranded RNA binding;0.0123247338335738!GO:0042325;regulation of phosphorylation;0.0123247338335738!GO:0016363;nuclear matrix;0.0125763748796244!GO:0002440;production of molecular mediator of immune response;0.0126555836343555!GO:0030098;lymphocyte differentiation;0.0126852931483953!GO:0008333;endosome to lysosome transport;0.0127165031890599!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0127384999931105!GO:0050851;antigen receptor-mediated signaling pathway;0.0127444835352551!GO:0030029;actin filament-based process;0.0127444835352551!GO:0019377;glycolipid catabolic process;0.0127444835352551!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0127933544395565!GO:0045047;protein targeting to ER;0.0127933544395565!GO:0032943;mononuclear cell proliferation;0.0132308667160275!GO:0046651;lymphocyte proliferation;0.0132308667160275!GO:0006352;transcription initiation;0.0132333742519954!GO:0005815;microtubule organizing center;0.0133154747800203!GO:0050900;leukocyte migration;0.0133325863173347!GO:0006665;sphingolipid metabolic process;0.0134811359220861!GO:0000209;protein polyubiquitination;0.0135363434689923!GO:0051092;activation of NF-kappaB transcription factor;0.0136173361158336!GO:0004185;serine carboxypeptidase activity;0.0136177966153947!GO:0046631;alpha-beta T cell activation;0.0137517683043087!GO:0000287;magnesium ion binding;0.0138099228685918!GO:0051345;positive regulation of hydrolase activity;0.0143581852391101!GO:0000785;chromatin;0.0143778793778104!GO:0000082;G1/S transition of mitotic cell cycle;0.0143895982453752!GO:0008139;nuclear localization sequence binding;0.0144971093889995!GO:0030217;T cell differentiation;0.0149975560505981!GO:0048471;perinuclear region of cytoplasm;0.01507681312573!GO:0002573;myeloid leukocyte differentiation;0.0150880386989953!GO:0006607;NLS-bearing substrate import into nucleus;0.015463977305738!GO:0030658;transport vesicle membrane;0.0156361662264575!GO:0031625;ubiquitin protein ligase binding;0.0159386028337675!GO:0042088;T-helper 1 type immune response;0.0161049474435248!GO:0030258;lipid modification;0.0161196311189849!GO:0051329;interphase of mitotic cell cycle;0.0162869758511777!GO:0045045;secretory pathway;0.0165856275752238!GO:0030127;COPII vesicle coat;0.016610401585248!GO:0012507;ER to Golgi transport vesicle membrane;0.016610401585248!GO:0051023;regulation of immunoglobulin secretion;0.0167034775179572!GO:0045994;positive regulation of translational initiation by iron;0.0167034775179572!GO:0006260;DNA replication;0.0171483407402034!GO:0005484;SNAP receptor activity;0.0173640370958295!GO:0000165;MAPKKK cascade;0.0174162113068569!GO:0051325;interphase;0.0174958247099553!GO:0042113;B cell activation;0.0175764906267829!GO:0030176;integral to endoplasmic reticulum membrane;0.0183517792111746!GO:0030867;rough endoplasmic reticulum membrane;0.0194134329320922!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0194296260795193!GO:0045792;negative regulation of cell size;0.0196202627270242!GO:0005070;SH3/SH2 adaptor activity;0.0197278712023224!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0198810285900468!GO:0046466;membrane lipid catabolic process;0.0201139965821726!GO:0003727;single-stranded RNA binding;0.0201139965821726!GO:0048146;positive regulation of fibroblast proliferation;0.0201139965821726!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0202362006468633!GO:0006350;transcription;0.0208544507539128!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0208778588717902!GO:0030027;lamellipodium;0.0211633637017656!GO:0042092;T-helper 2 type immune response;0.021177177787876!GO:0008624;induction of apoptosis by extracellular signals;0.0211971471754266!GO:0030693;caspase activity;0.0212934318396899!GO:0050776;regulation of immune response;0.0212934318396899!GO:0019207;kinase regulator activity;0.0214175872879521!GO:0002697;regulation of immune effector process;0.0214562403251245!GO:0002263;cell activation during immune response;0.0214562403251245!GO:0042093;T-helper cell differentiation;0.0214562403251245!GO:0002366;leukocyte activation during immune response;0.0214562403251245!GO:0002293;alpha-beta T cell differentiation during immune response;0.0214562403251245!GO:0002294;CD4-positive, alpha-beta T cell differentiation during immune response;0.0214562403251245!GO:0002285;lymphocyte activation during immune response;0.0214562403251245!GO:0002292;T cell differentiation during immune response;0.0214562403251245!GO:0002286;T cell activation during immune response;0.0214562403251245!GO:0043621;protein self-association;0.0216634896373665!GO:0019882;antigen processing and presentation;0.0220019694282521!GO:0043022;ribosome binding;0.0222479161146548!GO:0045089;positive regulation of innate immune response;0.0222740731931337!GO:0045088;regulation of innate immune response;0.0222740731931337!GO:0002467;germinal center formation;0.0222789750415048!GO:0042035;regulation of cytokine biosynthetic process;0.0223564024273306!GO:0030521;androgen receptor signaling pathway;0.0224064321206844!GO:0045639;positive regulation of myeloid cell differentiation;0.0227241138011896!GO:0030041;actin filament polymerization;0.0229516466792626!GO:0050870;positive regulation of T cell activation;0.0230651624804869!GO:0031328;positive regulation of cellular biosynthetic process;0.0230801711531881!GO:0030308;negative regulation of cell growth;0.0230949639126087!GO:0006458;'de novo' protein folding;0.0232721851749444!GO:0051084;'de novo' posttranslational protein folding;0.0232721851749444!GO:0008312;7S RNA binding;0.0233889173979431!GO:0050811;GABA receptor binding;0.0242938538709328!GO:0045746;negative regulation of Notch signaling pathway;0.0242938538709328!GO:0051051;negative regulation of transport;0.024300112127931!GO:0002237;response to molecule of bacterial origin;0.0245852746590033!GO:0046479;glycosphingolipid catabolic process;0.0250586063639913!GO:0030384;phosphoinositide metabolic process;0.0250586063639913!GO:0000049;tRNA binding;0.025486395444146!GO:0005048;signal sequence binding;0.025486395444146!GO:0001776;leukocyte homeostasis;0.0255043821555306!GO:0019883;antigen processing and presentation of endogenous antigen;0.0258569765906621!GO:0030155;regulation of cell adhesion;0.0259844558719827!GO:0051049;regulation of transport;0.0259844558719827!GO:0032763;regulation of mast cell cytokine production;0.026077203483228!GO:0032762;mast cell cytokine production;0.026077203483228!GO:0002224;toll-like receptor signaling pathway;0.0260851399870158!GO:0002221;pattern recognition receptor signaling pathway;0.0260851399870158!GO:0006414;translational elongation;0.0261030538427226!GO:0046467;membrane lipid biosynthetic process;0.0261030538427226!GO:0042613;MHC class II protein complex;0.0263949671161927!GO:0051252;regulation of RNA metabolic process;0.0265725095887427!GO:0015631;tubulin binding;0.0271526262140167!GO:0005149;interleukin-1 receptor binding;0.0276066784172651!GO:0030503;regulation of cell redox homeostasis;0.0276432050769897!GO:0006650;glycerophospholipid metabolic process;0.0278793925865203!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0280494605349413!GO:0002819;regulation of adaptive immune response;0.0280494605349413!GO:0003702;RNA polymerase II transcription factor activity;0.0282405325806501!GO:0019371;cyclooxygenase pathway;0.0284491541282628!GO:0030663;COPI coated vesicle membrane;0.0284491541282628!GO:0030126;COPI vesicle coat;0.0284491541282628!GO:0050865;regulation of cell activation;0.0284622718585005!GO:0007006;mitochondrial membrane organization and biogenesis;0.0284985839315831!GO:0030518;steroid hormone receptor signaling pathway;0.0284985839315831!GO:0048144;fibroblast proliferation;0.0289845985523019!GO:0048145;regulation of fibroblast proliferation;0.0289845985523019!GO:0030137;COPI-coated vesicle;0.0292033113792788!GO:0051052;regulation of DNA metabolic process;0.03051406693733!GO:0048002;antigen processing and presentation of peptide antigen;0.0306965704733042!GO:0006405;RNA export from nucleus;0.0307327193693576!GO:0019843;rRNA binding;0.0309852614212408!GO:0006984;ER-nuclear signaling pathway;0.0309852614212408!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0311211272065722!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0312578616495243!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0312578616495243!GO:0005138;interleukin-6 receptor binding;0.0314082483243639!GO:0005694;chromosome;0.0318627059075433!GO:0006644;phospholipid metabolic process;0.0322788624562946!GO:0042098;T cell proliferation;0.0323418128957696!GO:0030660;Golgi-associated vesicle membrane;0.0325659859839716!GO:0043407;negative regulation of MAP kinase activity;0.0326366777373066!GO:0032760;positive regulation of tumor necrosis factor production;0.0329786394062312!GO:0004177;aminopeptidase activity;0.0333961121423616!GO:0005350;pyrimidine transmembrane transporter activity;0.0333961121423616!GO:0015855;pyrimidine transport;0.0333961121423616!GO:0015288;porin activity;0.0333961121423616!GO:0033549;MAP kinase phosphatase activity;0.0334735035182747!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.0334735035182747!GO:0006749;glutathione metabolic process;0.0335745434256521!GO:0008286;insulin receptor signaling pathway;0.0335809239282888!GO:0016491;oxidoreductase activity;0.0336157462805807!GO:0030118;clathrin coat;0.0336157462805807!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0341927176285685!GO:0032635;interleukin-6 production;0.0350212376832498!GO:0042832;defense response to protozoan;0.0350678081294953!GO:0002443;leukocyte mediated immunity;0.0353542897902229!GO:0008538;proteasome activator activity;0.0353542897902229!GO:0032318;regulation of Ras GTPase activity;0.0356640332026496!GO:0051091;positive regulation of transcription factor activity;0.0357498058582049!GO:0006213;pyrimidine nucleoside metabolic process;0.0360222808747738!GO:0000738;DNA catabolic process, exonucleolytic;0.0362319885653182!GO:0002699;positive regulation of immune effector process;0.0365944582300917!GO:0046483;heterocycle metabolic process;0.0382132024432641!GO:0015036;disulfide oxidoreductase activity;0.038355479177976!GO:0030100;regulation of endocytosis;0.038355479177976!GO:0005869;dynactin complex;0.0387739684519043!GO:0051249;regulation of lymphocyte activation;0.0390708825573938!GO:0000339;RNA cap binding;0.0390708825573938!GO:0006310;DNA recombination;0.0390708825573938!GO:0007162;negative regulation of cell adhesion;0.0390708825573938!GO:0051540;metal cluster binding;0.0390708825573938!GO:0051536;iron-sulfur cluster binding;0.0390708825573938!GO:0008320;protein transmembrane transporter activity;0.0390799187732115!GO:0006261;DNA-dependent DNA replication;0.0391679512483286!GO:0030134;ER to Golgi transport vesicle;0.0393201391540117!GO:0019901;protein kinase binding;0.0393424311405028!GO:0009306;protein secretion;0.0396358789687486!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0397791235211945!GO:0051101;regulation of DNA binding;0.0397849489899805!GO:0005669;transcription factor TFIID complex;0.0400069982628028!GO:0033033;negative regulation of myeloid cell apoptosis;0.0400155904241442!GO:0001803;regulation of type III hypersensitivity;0.0400155904241442!GO:0032733;positive regulation of interleukin-10 production;0.0400155904241442!GO:0033025;regulation of mast cell apoptosis;0.0400155904241442!GO:0001805;positive regulation of type III hypersensitivity;0.0400155904241442!GO:0033023;mast cell homeostasis;0.0400155904241442!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0400155904241442!GO:0033032;regulation of myeloid cell apoptosis;0.0400155904241442!GO:0001802;type III hypersensitivity;0.0400155904241442!GO:0033028;myeloid cell apoptosis;0.0400155904241442!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0400155904241442!GO:0033026;negative regulation of mast cell apoptosis;0.0400155904241442!GO:0033024;mast cell apoptosis;0.0400155904241442!GO:0051087;chaperone binding;0.0400225719949126!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0404077094169438!GO:0002821;positive regulation of adaptive immune response;0.0404077094169438!GO:0050727;regulation of inflammatory response;0.0404077094169438!GO:0031347;regulation of defense response;0.0404077094169438!GO:0042226;interleukin-6 biosynthetic process;0.0406857971966223!GO:0006914;autophagy;0.0406857971966223!GO:0006626;protein targeting to mitochondrion;0.0410713509300617!GO:0008361;regulation of cell size;0.0410823372813133!GO:0042405;nuclear inclusion body;0.0415200681095447!GO:0042992;negative regulation of transcription factor import into nucleus;0.0415200681095447!GO:0042308;negative regulation of protein import into nucleus;0.0415200681095447!GO:0044255;cellular lipid metabolic process;0.0415396986690246!GO:0042585;germinal vesicle;0.0415969830354846!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0417551992320086!GO:0042348;NF-kappaB import into nucleus;0.0417976828545398!GO:0042345;regulation of NF-kappaB import into nucleus;0.0417976828545398!GO:0043681;protein import into mitochondrion;0.0418503247492885!GO:0001562;response to protozoan;0.0429561761834861!GO:0016311;dephosphorylation;0.042999511239436!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.042999511239436!GO:0015002;heme-copper terminal oxidase activity;0.042999511239436!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.042999511239436!GO:0004129;cytochrome-c oxidase activity;0.042999511239436!GO:0008287;protein serine/threonine phosphatase complex;0.0431020885596878!GO:0031327;negative regulation of cellular biosynthetic process;0.0435054614707454!GO:0006302;double-strand break repair;0.0437633455320412!GO:0030433;ER-associated protein catabolic process;0.0437633455320412!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0437633455320412!GO:0008656;caspase activator activity;0.0442559122375103!GO:0000119;mediator complex;0.0442559122375103!GO:0004722;protein serine/threonine phosphatase activity;0.0444877552159329!GO:0043300;regulation of leukocyte degranulation;0.0449056272258027!GO:0030377;U-plasminogen activator receptor activity;0.0449056272258027!GO:0030968;unfolded protein response;0.0449056272258027!GO:0002444;myeloid leukocyte mediated immunity;0.0449083018793398!GO:0030031;cell projection biogenesis;0.0452086843342326!GO:0043488;regulation of mRNA stability;0.045522398782993!GO:0043487;regulation of RNA stability;0.045522398782993!GO:0051881;regulation of mitochondrial membrane potential;0.0457379224758187!GO:0006334;nucleosome assembly;0.0465467085958663!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0465624987404125!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0484228553447597!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0484228553447597!GO:0009126;purine nucleoside monophosphate metabolic process;0.0484228553447597!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0484228553447597!GO:0019783;small conjugating protein-specific protease activity;0.0484421022935154!GO:0045926;negative regulation of growth;0.0490957494801922!GO:0045936;negative regulation of phosphate metabolic process;0.0495288406164584!GO:0051347;positive regulation of transferase activity;0.0497658107263448!GO:0051607;defense response to virus;0.0497658107263448!GO:0046979;TAP2 binding;0.0497658107263448!GO:0046977;TAP binding;0.0497658107263448!GO:0046978;TAP1 binding;0.0497658107263448!GO:0017091;AU-rich element binding;0.0499852312662143!GO:0050779;RNA destabilization;0.0499852312662143!GO:0000289;poly(A) tail shortening;0.0499852312662143!GO:0019955;cytokine binding;0.0499852312662143 | |||
|sample_id=11885 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=IRF7:6.20002226303;HLF:5.7662540421;NFE2:5.56900081549;FOS_FOS{B,L1}_JUN{B,D}:5.46820917377;NFIL3:5.27257889193;BACH2:5.14482396247;NFE2L2:5.11408882639;IRF1,2:5.10969153141;NFKB1_REL_RELA:5.10197540961;CEBPA,B_DDIT3:5.09415804329;FOSL2:5.04260997879;PAX8:4.62728748717;FOXP3:4.27857402622;PAX2:4.22663635574;STAT5{A,B}:4.19303186086;SPIB:3.82433587014;NFATC1..3:3.77204596765;HSF1,2:3.6088027941;SPI1:3.39746254476;DMAP1_NCOR{1,2}_SMARC:3.31670388138;ATF5_CREB3:3.19583462169;ETS1,2:3.06988213942;NANOG{mouse}:3.06500795078;STAT2,4,6:3.02993821365;CDX1,2,4:2.81113889428;ATF4:2.54008910761;SREBF1,2:2.49321356982;CREB1:2.46164486913;RUNX1..3:2.44435429298;HMGA1,2:2.37956394696;JUN:2.33733630609;FOXN1:2.28579512053;ATF2:2.11185981932;ATF6:2.07536608083;PAX3,7:1.95994308881;NFE2L1:1.86530227217;ALX4:1.74310640976;PDX1:1.56877169575;RXRA_VDR{dimer}:1.41748264304;ELF1,2,4:1.36611224666;XBP1:1.33073302315;NR1H4:1.29611484765;TGIF1:1.24523919406;POU2F1..3:1.12094259133;MAFB:1.11572747348;PPARG:1.00809663875;ZBTB16:0.978507432868;IKZF1:0.929164371167;HOX{A5,B5}:0.894905499553;RBPJ:0.862787527124;TBP:0.862499807956;FOXO1,3,4:0.740964947899;SRF:0.655405124412;HOXA9_MEIS1:0.631425362209;EN1,2:0.609969567425;OCT4_SOX2{dimer}:0.607691969787;STAT1,3:0.561345553713;NR3C1:0.560726964675;PRDM1:0.489151626217;PAX4:0.416687862405;BPTF:0.315998730527;POU5F1:0.289792100803;ALX1:0.275628193051;VSX1,2:0.211015811578;EP300:0.149222392662;GLI1..3:0.133107605009;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.0689055811521;PAX1,9:0.0488816274461;TLX2:0.0259769567;NANOG:-0.0206358964705;HBP1_HMGB_SSRP1_UBTF:-0.0691894913435;RORA:-0.294229051115;GATA4:-0.306938823289;AHR_ARNT_ARNT2:-0.316743585814;HIF1A:-0.343314725771;NKX3-1:-0.379373250475;MEF2{A,B,C,D}:-0.429597271225;SOX2:-0.521905623419;FOX{D1,D2}:-0.522464392263;NR6A1:-0.540271713866;POU3F1..4:-0.54536795748;EGR1..3:-0.562294292607;IKZF2:-0.588101518504;FOXM1:-0.618923811165;RFX2..5_RFXANK_RFXAP:-0.632288330819;SMAD1..7,9:-0.70340422449;NFIX:-0.735120501396;FOXL1:-0.781424850221;MYB:-0.818716111333;DBP:-0.822515552777;TFCP2:-0.834740833787;HMX1:-0.844402611395;PRRX1,2:-0.851330144061;ADNP_IRX_SIX_ZHX:-0.879521736863;CRX:-0.890682952443;PAX6:-0.927069323183;SOX5:-0.980675560172;FOXD3:-0.987404493286;TAL1_TCF{3,4,12}:-1.00364565418;HES1:-1.01753588957;CDC5L:-1.1486298445;FOXA2:-1.2077139945;POU6F1:-1.26748248642;TEF:-1.27802542871;MZF1:-1.29436237568;SPZ1:-1.31713375593;NHLH1,2:-1.3349136137;ESR1:-1.34660588898;PITX1..3:-1.34872288626;REST:-1.3906144623;HNF4A_NR2F1,2:-1.40520766227;HOX{A4,D4}:-1.40787830978;E2F1..5:-1.44715173035;RFX1:-1.44766677264;NKX2-2,8:-1.46887143008;HNF1A:-1.47717269318;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.50854323497;MYFfamily:-1.52837787094;FOX{F1,F2,J1}:-1.52941883917;MED-1{core}:-1.54832619452;ESRRA:-1.55803397914;ZFP161:-1.66396643623;GTF2A1,2:-1.67479758248;ZNF384:-1.70792569753;ZNF238:-1.7135817732;MTE{core}:-1.759965966;CUX2:-1.76340352765;FOXP1:-1.78637362419;TEAD1:-1.84262420086;NKX2-1,4:-1.84843281828;GATA6:-1.90005092106;BREu{core}:-1.93073800518;NKX6-1,2:-1.99869414067;SP1:-2.02061955489;TBX4,5:-2.02223880239;NKX2-3_NKX2-5:-2.03790915392;MYBL2:-2.05282188499;ZBTB6:-2.09388679276;TFDP1:-2.10686902721;HOX{A6,A7,B6,B7}:-2.10800934069;GTF2I:-2.12250228874;SOX{8,9,10}:-2.13656227416;POU1F1:-2.13866342646;ZNF148:-2.21389633466;ELK1,4_GABP{A,B1}:-2.24063645146;TLX1..3_NFIC{dimer}:-2.25792183494;ZEB1:-2.26351557831;GZF1:-2.30449605785;RXR{A,B,G}:-2.30544151344;PATZ1:-2.32177781349;NFY{A,B,C}:-2.32694903358;TFAP4:-2.33557212737;ONECUT1,2:-2.33656963363;TFAP2B:-2.367679967;FOX{I1,J2}:-2.39716289019;NKX3-2:-2.4111227053;MTF1:-2.42729886394;SOX17:-2.43613149107;GFI1B:-2.44973541559;SNAI1..3:-2.48518634851;TP53:-2.4899283084;MAZ:-2.51429518559;XCPE1{core}:-2.53971474197;T:-2.56135281301;GCM1,2:-2.5686900606;ARID5B:-2.60504068121;KLF4:-2.64941004177;TFAP2{A,C}:-2.75846669899;HIC1:-2.76940681943;MYOD1:-2.78980375764;ZIC1..3:-2.94050049396;PBX1:-3.04995594704;EVI1:-3.05022800818;UFEwm:-3.05141827631;bHLH_family:-3.06546006622;AIRE:-3.0989814513;NR5A1,2:-3.11801778035;RREB1:-3.15268808438;EBF1:-3.17210881525;GFI1:-3.21045979708;FOXQ1:-3.21939024529;YY1:-3.32399323697;NRF1:-3.32437192431;PAX5:-3.44826237898;LMO2:-3.64578265091;LHX3,4:-3.83775609932;ZNF423:-3.89810574382;AR:-3.93365574311;ZNF143:-4.00814151883;LEF1_TCF7_TCF7L1,2:-4.07225038205;TOPORS:-4.52909381901;HAND1,2:-5.23271588434 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11885-125D4;search_select_hide=table117:FF:11885-125D4 | |||
}} | }} |
Latest revision as of 18:26, 4 June 2020
Name: | CD14+ monocytes - treated with lipopolysaccharide, donor3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13545 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13545
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13545
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0912 |
10 | 10 | 0.0236 |
100 | 100 | 0.91 |
101 | 101 | 0.982 |
102 | 102 | 0.916 |
103 | 103 | 0.216 |
104 | 104 | 0.497 |
105 | 105 | 0.179 |
106 | 106 | 7.14567e-4 |
107 | 107 | 0.236 |
108 | 108 | 0.614 |
109 | 109 | 0.299 |
11 | 11 | 0.149 |
110 | 110 | 0.148 |
111 | 111 | 0.113 |
112 | 112 | 0.427 |
113 | 113 | 0.429 |
114 | 114 | 0.0317 |
115 | 115 | 0.156 |
116 | 116 | 0.885 |
117 | 117 | 0.0846 |
118 | 118 | 0.209 |
119 | 119 | 0.124 |
12 | 12 | 0.297 |
120 | 120 | 0.563 |
121 | 121 | 0.773 |
122 | 122 | 0.7 |
123 | 123 | 0.611 |
124 | 124 | 0.836 |
125 | 125 | 0.168 |
126 | 126 | 0.226 |
127 | 127 | 0.577 |
128 | 128 | 0.0706 |
129 | 129 | 0.328 |
13 | 13 | 0.0827 |
130 | 130 | 0.433 |
131 | 131 | 0.917 |
132 | 132 | 0.122 |
133 | 133 | 0.878 |
134 | 134 | 0.566 |
135 | 135 | 0.756 |
136 | 136 | 0.766 |
137 | 137 | 0.0344 |
138 | 138 | 0.506 |
139 | 139 | 0.112 |
14 | 14 | 0.546 |
140 | 140 | 0.601 |
141 | 141 | 0.261 |
142 | 142 | 0.235 |
143 | 143 | 0.0315 |
144 | 144 | 0.445 |
145 | 145 | 0.299 |
146 | 146 | 0.872 |
147 | 147 | 0.869 |
148 | 148 | 0.0108 |
149 | 149 | 0.97 |
15 | 15 | 0.156 |
150 | 150 | 0.31 |
151 | 151 | 0.602 |
152 | 152 | 0.541 |
153 | 153 | 0.802 |
154 | 154 | 0.795 |
155 | 155 | 0.853 |
156 | 156 | 0.7 |
157 | 157 | 0.863 |
158 | 158 | 0.0946 |
159 | 159 | 0.0737 |
16 | 16 | 0.313 |
160 | 160 | 0.404 |
161 | 161 | 0.41 |
162 | 162 | 0.253 |
163 | 163 | 0.158 |
164 | 164 | 0.168 |
165 | 165 | 0.18 |
166 | 166 | 0.999 |
167 | 167 | 0.281 |
168 | 168 | 0.0735 |
169 | 169 | 0.0193 |
17 | 17 | 0.274 |
18 | 18 | 0.111 |
19 | 19 | 0.555 |
2 | 2 | 0.398 |
20 | 20 | 0.173 |
21 | 21 | 0.81 |
22 | 22 | 0.346 |
23 | 23 | 0.0393 |
24 | 24 | 0.384 |
25 | 25 | 0.418 |
26 | 26 | 0.0591 |
27 | 27 | 0.565 |
28 | 28 | 0.308 |
29 | 29 | 0.243 |
3 | 3 | 0.12 |
30 | 30 | 0.365 |
31 | 31 | 0.719 |
32 | 32 | 0.411 |
33 | 33 | 0.161 |
34 | 34 | 0.771 |
35 | 35 | 0.108 |
36 | 36 | 0.0594 |
37 | 37 | 0.065 |
38 | 38 | 0.397 |
39 | 39 | 0.782 |
4 | 4 | 0.921 |
40 | 40 | 0.192 |
41 | 41 | 0.0283 |
42 | 42 | 0.294 |
43 | 43 | 0.0198 |
44 | 44 | 0.537 |
45 | 45 | 0.75 |
46 | 46 | 0.187 |
47 | 47 | 0.501 |
48 | 48 | 0.477 |
49 | 49 | 0.153 |
5 | 5 | 0.296 |
50 | 50 | 0.947 |
51 | 51 | 0.56 |
52 | 52 | 0.349 |
53 | 53 | 0.67 |
54 | 54 | 0.482 |
55 | 55 | 0.62 |
56 | 56 | 0.697 |
57 | 57 | 0.835 |
58 | 58 | 0.185 |
59 | 59 | 0.247 |
6 | 6 | 0.747 |
60 | 60 | 0.04 |
61 | 61 | 0.729 |
62 | 62 | 0.0928 |
63 | 63 | 0.533 |
64 | 64 | 0.484 |
65 | 65 | 0.232 |
66 | 66 | 0.424 |
67 | 67 | 0.399 |
68 | 68 | 0.461 |
69 | 69 | 0.21 |
7 | 7 | 0.218 |
70 | 70 | 0.0435 |
71 | 71 | 0.0284 |
72 | 72 | 0.193 |
73 | 73 | 0.268 |
74 | 74 | 0.0454 |
75 | 75 | 0.146 |
76 | 76 | 0.171 |
77 | 77 | 0.563 |
78 | 78 | 0.122 |
79 | 79 | 0.693 |
8 | 8 | 0.337 |
80 | 80 | 0.158 |
81 | 81 | 0.289 |
82 | 82 | 0.203 |
83 | 83 | 0.033 |
84 | 84 | 0.0836 |
85 | 85 | 0.0517 |
86 | 86 | 0.0831 |
87 | 87 | 0.341 |
88 | 88 | 0.758 |
89 | 89 | 0.213 |
9 | 9 | 0.389 |
90 | 90 | 0.0838 |
91 | 91 | 0.437 |
92 | 92 | 0.27 |
93 | 93 | 0.489 |
94 | 94 | 0.0886 |
95 | 95 | 0.538 |
96 | 96 | 0.404 |
97 | 97 | 0.466 |
98 | 98 | 0.156 |
99 | 99 | 0.0948 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13545
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011108 human CD14-positive monocytes - treated with lipopolysaccharide sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000335 (LPS treatment sample)
0011108 (human CD14-positive monocytes - treated with lipopolysaccharide sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)