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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0002432;granuloma formation;0.0053323106864007;70450!GO:0002544;chronic inflammatory response;0.0053323106864007;70450!GO:0043320;natural killer cell degranulation;0.0053323106864007;70450!GO:0002467;germinal center formation;0.0133260291583405;70450!GO:0051607;defense response to virus;0.0133260291583405;70450!GO:0043299;leukocyte degranulation;0.0133260291583405;70450!GO:0030101;natural killer cell activation;0.0133260291583405;70450!GO:0042267;natural killer cell mediated cytotoxicity;0.0133260291583405;70450!GO:0002228;natural killer cell mediated immunity;0.0133260291583405;70450!GO:0001909;leukocyte mediated cytotoxicity;0.015988167337366;70450!GO:0001906;cell killing;0.015988167337366;70450!GO:0006909;phagocytosis;0.0253034963031704;70450!GO:0009615;response to virus;0.0301092466608259;70450!GO:0045055;regulated secretory pathway;0.0365023118205945;70450!GO:0006887;exocytosis;0.0386339251212221;70450!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0386339251212221;70450!GO:0045087;innate immune response;0.0386339251212221;70450!GO:0002250;adaptive immune response;0.0386339251212221;70450!GO:0002449;lymphocyte mediated immunity;0.0386339251212221;70450!GO:0002443;leukocyte mediated immunity;0.0394871973167848;70450!GO:0006917;induction of apoptosis;0.0467369230396592;70450!GO:0012502;induction of programmed cell death;0.0467369230396592;70450!GO:0002252;immune effector process;0.0467764630209545;70450!GO:0043065;positive regulation of apoptosis;0.0477725546038868;70450!GO:0051707;response to other organism;0.0477725546038868;70450!GO:0043068;positive regulation of programmed cell death;0.0477725546038868;70450!GO:0010324;membrane invagination;0.0477725546038868;70450!GO:0006897;endocytosis;0.0477725546038868;70450!GO:0045045;secretory pathway;0.0480378536669127;70450!GO:0046649;lymphocyte activation;0.0488882263578446;70450!GO:0045321;leukocyte activation;0.0488882263578446;70450!GO:0032940;secretion by cell;0.0488882263578446;70450!GO:0006954;inflammatory response;0.0488882263578446;70450!GO:0009607;response to biotic stimulus;0.0488882263578446;70450!}}
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immunoglobulin superfamily domains;0.0386339251212221;70450!GO:0045087;innate immune response;0.0386339251212221;70450!GO:0002250;adaptive immune response;0.0386339251212221;70450!GO:0002449;lymphocyte mediated immunity;0.0386339251212221;70450!GO:0002443;leukocyte mediated immunity;0.0394871973167848;70450!GO:0006917;induction of apoptosis;0.0467369230396592;70450!GO:0012502;induction of programmed cell death;0.0467369230396592;70450!GO:0002252;immune effector process;0.0467764630209545;70450!GO:0043065;positive regulation of apoptosis;0.0477725546038868;70450!GO:0051707;response to other organism;0.0477725546038868;70450!GO:0043068;positive regulation of programmed cell death;0.0477725546038868;70450!GO:0010324;membrane invagination;0.0477725546038868;70450!GO:0006897;endocytosis;0.0477725546038868;70450!GO:0045045;secretory pathway;0.0480378536669127;70450!GO:0046649;lymphocyte activation;0.0488882263578446;70450!GO:0045321;leukocyte activation;0.0488882263578446;70450!GO:0032940;secretion by cell;0.0488882263578446;70450!GO:0006954;inflammatory response;0.0488882263578446;70450!GO:0009607;response to biotic stimulus;0.0488882263578446;70450!|ontology_enrichment_celltype=CL:0000988!1.42e-09!32;CL:0002032!1.42e-09!32;CL:0000037!1.42e-09!32;CL:0000566!1.42e-09!32;CL:0000837!1.42e-09!32;CL:0002031!4.52e-08!25;CL:0002242!7.15e-08!16;CL:0000050!3.06e-07!9|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0004177!6.41e-11!29;UBERON:0005057!6.41e-11!29;UBERON:0002390!1.83e-10!45;UBERON:0003061!1.83e-10!45;UBERON:0002193!7.03e-10!48;UBERON:0002405!7.03e-10!48;UBERON:0001041!7.76e-09!80;UBERON:0000077!1.59e-08!35;UBERON:0002370!3.80e-07!23;UBERON:0000974!3.80e-07!23;UBERON:0004807!3.80e-07!23;UBERON:0005058!3.80e-07!23;UBERON:0003351!3.80e-07!23;UBERON:0009113!3.80e-07!23;UBERON:0003295!3.80e-07!23;UBERON:0009722!3.80e-07!23;UBERON:0005562!3.80e-07!23;UBERON:0007690!3.80e-07!23|tfbs_overrepresentation_for_novel_motifs=0.752782,0.564138,0.722405,0.801166,0.587814,0.81763,0.919454,0.467321,0.479531,2.68971,0.870507,0.906098,0.467629,0.933025,1.47843,0,1.14208,0.578045,0.448066,0.876292,0.679146,1.38557,0.932027,0.585919,0.731217,0.963352,0.437236,0.841386,0.64294,1.7585,0.825437,1.24901,0.575271,0.411696,0.608816,2.7168,0.563758,0.902078,0.536514,0.50014,0.582863,0.831295,0.261619,0.610669,0.474221,0.788421,1.05665,0.859154,0.663409,1.55852,1.12346,0.99279,0.371606,1.3966,1.41464,0.940919,0.657156,0.891887,0.425455,0.938668,1.22795,1.00308,1.23806,1.11142,0.953187,1.15459,1.55483,1.90983,1.22303,1.7608,0.700291,0.474956,0.284975,1.44925,0.416814,0.402065,1.05896,1.04436,1.20986,0.684144,0.476502,1.16055,1.00151,0.459035,1.32978,0.181575,0.568545,0.380977,1.06194,2.07346,1.62608,1.33496,1.26245,0.595071,0.531443,0.509215,0.464141,1.26539,1.05692,0.352122,0.563856,1.24872,1.37854,1.12409,1.12297,0.830796,1.18646,0.854628,0.689894,0.681267,0.744607,1.38039,0.685481,0.876299,1.63327,0.580657,1.1471,0.805461,1.14346,0.559153,1.45481,1.08896,0.965352,1.04338,1.68841,1.21376,0.928483,1.25534,1.55328,0.598722,1.36093,1.862,1.52297,0.955954,3.60838,0.273451,0.762499,0.832891,1.60513,2.44352,2.04137,1.55966,0.978551,1.26,1.11604,0.831808,1.06002,2.40374,0.765221,0.589976,1.77018,0.260379,1.39822,0.516739,0.954936,1.48249,0.993889,0.622823,0.749933,0.762177,1.61484,1.32889,1.21423,0.741984,1.11251,0.94678,0.562367,0.904334,0.833542|tfbs_overrepresentation_jaspar=MA0003.1;0.0699972,MA0004.1;0.801718,MA0006.1;0.60285,MA0007.1;0.784593,MA0009.1;1.27673,MA0014.1;0.133574,MA0017.1;0.635031,MA0019.1;1.08369,MA0024.1;1.23079,MA0025.1;1.51835,MA0027.1;2.9431,MA0028.1;0.61552,MA0029.1;1.20789,MA0030.1;1.21482,MA0031.1;1.17722,MA0038.1;0.963265,MA0040.1;1.28983,MA0041.1;0.714279,MA0042.1;0.69885,MA0043.1;1.3775,MA0046.1;1.31428,MA0048.1;0.353763,MA0050.1;0.845669,MA0051.1;0.973068,MA0052.1;1.29825,MA0055.1;1.06076,MA0056.1;0,MA0057.1;0.896032,MA0058.1;0.690848,MA0059.1;0.705317,MA0060.1;0.502699,MA0061.1;0.5406,MA0063.1;0,MA0066.1;0.951196,MA0067.1;1.63197,MA0068.1;0.343188,MA0069.1;1.29861,MA0070.1;1.28847,MA0071.1;0.844726,MA0072.1;1.2796,MA0073.1;0.00834468,MA0074.1;0.911576,MA0076.1;0.657929,MA0077.1;1.2569,MA0078.1;1.0091,MA0081.1;1.73701,MA0083.1;1.37668,MA0084.1;1.96428,MA0087.1;1.33189,MA0088.1;0.27999,MA0089.1;0,MA0090.1;0.762482,MA0091.1;0.816659,MA0092.1;0.762845,MA0093.1;0.62555,MA0095.1;0,MA0098.1;0,MA0100.1;0.89873,MA0101.1;0.71579,MA0103.1;0.647985,MA0105.1;1.04599,MA0106.1;1.01755,MA0107.1;0.640607,MA0108.2;1.10817,MA0109.1;0,MA0111.1;0.778753,MA0113.1;0.986839,MA0114.1;0.537669,MA0115.1;1.38041,MA0116.1;0.602598,MA0117.1;1.34691,MA0119.1;0.716476,MA0122.1;1.36752,MA0124.1;1.57762,MA0125.1;1.5017,MA0130.1;0,MA0131.1;1.07881,MA0132.1;0,MA0133.1;0,MA0135.1;1.4152,MA0136.1;0.933582,MA0139.1;1.16863,MA0140.1;0.898603,MA0141.1;0.671467,MA0142.1;1.16183,MA0143.1;1.00467,MA0144.1;0.541532,MA0145.1;0.794492,MA0146.1;0.900029,MA0147.1;0.556853,MA0148.1;0.820161,MA0149.1;0.722227,MA0062.2;1.06145,MA0035.2;0.903829,MA0039.2;0.40695,MA0138.2;1.07027,MA0002.2;3.03802,MA0137.2;0.668025,MA0104.2;0.48458,MA0047.2;0.962424,MA0112.2;0.29236,MA0065.2;0.79573,MA0150.1;0.784464,MA0151.1;0,MA0152.1;0.962542,MA0153.1;1.43238,MA0154.1;0.35067,MA0155.1;0.312898,MA0156.1;0.656895,MA0157.1;1.12772,MA0158.1;0,MA0159.1;0.569393,MA0160.1;0.823568,MA0161.1;0,MA0162.1;0.166722,MA0163.1;0.157796,MA0164.1;0.933981,MA0080.2;1.54848,MA0018.2;0.944669,MA0099.2;1.06348,MA0079.2;0.0831329,MA0102.2;2.01714,MA0258.1;0.520639,MA0259.1;0.543506,MA0442.1;0}}

Latest revision as of 18:51, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:115939241..115939266,-p6@Unc13d
Mm9::chr7:150191582..150191608,+p1@Tspan32
Mm9::chr7:150191623..150191640,+p4@Tspan32


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0002432granuloma formation0.0053323106864007
GO:0002544chronic inflammatory response0.0053323106864007
GO:0043320natural killer cell degranulation0.0053323106864007
GO:0002467germinal center formation0.0133260291583405
GO:0051607defense response to virus0.0133260291583405
GO:0043299leukocyte degranulation0.0133260291583405
GO:0030101natural killer cell activation0.0133260291583405
GO:0042267natural killer cell mediated cytotoxicity0.0133260291583405
GO:0002228natural killer cell mediated immunity0.0133260291583405
GO:0001909leukocyte mediated cytotoxicity0.015988167337366
GO:0001906cell killing0.015988167337366
GO:0006909phagocytosis0.0253034963031704
GO:0009615response to virus0.0301092466608259
GO:0045055regulated secretory pathway0.0365023118205945
GO:0006887exocytosis0.0386339251212221
GO:0002460adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains0.0386339251212221
GO:0045087innate immune response0.0386339251212221
GO:0002250adaptive immune response0.0386339251212221
GO:0002449lymphocyte mediated immunity0.0386339251212221
GO:0002443leukocyte mediated immunity0.0394871973167848
GO:0006917induction of apoptosis0.0467369230396592
GO:0012502induction of programmed cell death0.0467369230396592
GO:0002252immune effector process0.0467764630209545
GO:0043065positive regulation of apoptosis0.0477725546038868
GO:0051707response to other organism0.0477725546038868
GO:0043068positive regulation of programmed cell death0.0477725546038868
GO:0010324membrane invagination0.0477725546038868
GO:0006897endocytosis0.0477725546038868
GO:0045045secretory pathway0.0480378536669127
GO:0046649lymphocyte activation0.0488882263578446
GO:0045321leukocyte activation0.0488882263578446
GO:0032940secretion by cell0.0488882263578446
GO:0006954inflammatory response0.0488882263578446
GO:0009607response to biotic stimulus0.0488882263578446



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0699972
MA0004.10.801718
MA0006.10.60285
MA0007.10.784593
MA0009.11.27673
MA0014.10.133574
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.10.714279
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.10.353763
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.11.06076
MA0056.10
MA0057.10.896032
MA0058.10.690848
MA0059.10.705317
MA0060.10.502699
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.10.00834468
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.11.73701
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.10.27999
MA0089.10
MA0090.10.762482
MA0091.10.816659
MA0092.10.762845
MA0093.10.62555
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.10.71579
MA0103.10.647985
MA0105.11.04599
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.10.537669
MA0115.11.38041
MA0116.10.602598
MA0117.11.34691
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.11.16863
MA0140.10.898603
MA0141.10.671467
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.10.794492
MA0146.10.900029
MA0147.10.556853
MA0148.10.820161
MA0149.10.722227
MA0062.21.06145
MA0035.20.903829
MA0039.20.40695
MA0138.21.07027
MA0002.23.03802
MA0137.20.668025
MA0104.20.48458
MA0047.20.962424
MA0112.20.29236
MA0065.20.79573
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.35067
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.10.569393
MA0160.10.823568
MA0161.10
MA0162.10.166722
MA0163.10.157796
MA0164.10.933981
MA0080.21.54848
MA0018.20.944669
MA0099.21.06348
MA0079.20.0831329
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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