MCL coexpression mm9:2636
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr11:115939241..115939266,- | p6@Unc13d |
| Mm9::chr7:150191582..150191608,+ | p1@Tspan32 |
| Mm9::chr7:150191623..150191640,+ | p4@Tspan32 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0002432 | granuloma formation | 0.0053323106864007 |
| GO:0002544 | chronic inflammatory response | 0.0053323106864007 |
| GO:0043320 | natural killer cell degranulation | 0.0053323106864007 |
| GO:0002467 | germinal center formation | 0.0133260291583405 |
| GO:0051607 | defense response to virus | 0.0133260291583405 |
| GO:0043299 | leukocyte degranulation | 0.0133260291583405 |
| GO:0030101 | natural killer cell activation | 0.0133260291583405 |
| GO:0042267 | natural killer cell mediated cytotoxicity | 0.0133260291583405 |
| GO:0002228 | natural killer cell mediated immunity | 0.0133260291583405 |
| GO:0001909 | leukocyte mediated cytotoxicity | 0.015988167337366 |
| GO:0001906 | cell killing | 0.015988167337366 |
| GO:0006909 | phagocytosis | 0.0253034963031704 |
| GO:0009615 | response to virus | 0.0301092466608259 |
| GO:0045055 | regulated secretory pathway | 0.0365023118205945 |
| GO:0006887 | exocytosis | 0.0386339251212221 |
| GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0386339251212221 |
| GO:0045087 | innate immune response | 0.0386339251212221 |
| GO:0002250 | adaptive immune response | 0.0386339251212221 |
| GO:0002449 | lymphocyte mediated immunity | 0.0386339251212221 |
| GO:0002443 | leukocyte mediated immunity | 0.0394871973167848 |
| GO:0006917 | induction of apoptosis | 0.0467369230396592 |
| GO:0012502 | induction of programmed cell death | 0.0467369230396592 |
| GO:0002252 | immune effector process | 0.0467764630209545 |
| GO:0043065 | positive regulation of apoptosis | 0.0477725546038868 |
| GO:0051707 | response to other organism | 0.0477725546038868 |
| GO:0043068 | positive regulation of programmed cell death | 0.0477725546038868 |
| GO:0010324 | membrane invagination | 0.0477725546038868 |
| GO:0006897 | endocytosis | 0.0477725546038868 |
| GO:0045045 | secretory pathway | 0.0480378536669127 |
| GO:0046649 | lymphocyte activation | 0.0488882263578446 |
| GO:0045321 | leukocyte activation | 0.0488882263578446 |
| GO:0032940 | secretion by cell | 0.0488882263578446 |
| GO:0006954 | inflammatory response | 0.0488882263578446 |
| GO:0009607 | response to biotic stimulus | 0.0488882263578446 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| hematopoietic cell | 1.42e-09 | 32 |
| hematopoietic oligopotent progenitor cell | 1.42e-09 | 32 |
| hematopoietic stem cell | 1.42e-09 | 32 |
| angioblastic mesenchymal cell | 1.42e-09 | 32 |
| hematopoietic multipotent progenitor cell | 1.42e-09 | 32 |
| hematopoietic lineage restricted progenitor cell | 4.52e-08 | 25 |
| nucleate cell | 7.15e-08 | 16 |
| megakaryocyte-erythroid progenitor cell | 3.06e-07 | 9 |
| Ontology term | p-value | n |
|---|---|---|
| hemopoietic organ | 6.41e-11 | 29 |
| immune organ | 6.41e-11 | 29 |
| hematopoietic system | 1.83e-10 | 45 |
| blood island | 1.83e-10 | 45 |
| hemolymphoid system | 7.03e-10 | 48 |
| immune system | 7.03e-10 | 48 |
| foregut | 7.76e-09 | 80 |
| mixed endoderm/mesoderm-derived structure | 1.59e-08 | 35 |
| thymus | 3.80e-07 | 23 |
| neck | 3.80e-07 | 23 |
| respiratory system epithelium | 3.80e-07 | 23 |
| hemolymphoid system gland | 3.80e-07 | 23 |
| pharyngeal epithelium | 3.80e-07 | 23 |
| thymic region | 3.80e-07 | 23 |
| pharyngeal gland | 3.80e-07 | 23 |
| entire pharyngeal arch endoderm | 3.80e-07 | 23 |
| thymus primordium | 3.80e-07 | 23 |
| early pharyngeal endoderm | 3.80e-07 | 23 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.0699972 |
| MA0004.1 | 0.801718 |
| MA0006.1 | 0.60285 |
| MA0007.1 | 0.784593 |
| MA0009.1 | 1.27673 |
| MA0014.1 | 0.133574 |
| MA0017.1 | 0.635031 |
| MA0019.1 | 1.08369 |
| MA0024.1 | 1.23079 |
| MA0025.1 | 1.51835 |
| MA0027.1 | 2.9431 |
| MA0028.1 | 0.61552 |
| MA0029.1 | 1.20789 |
| MA0030.1 | 1.21482 |
| MA0031.1 | 1.17722 |
| MA0038.1 | 0.963265 |
| MA0040.1 | 1.28983 |
| MA0041.1 | 0.714279 |
| MA0042.1 | 0.69885 |
| MA0043.1 | 1.3775 |
| MA0046.1 | 1.31428 |
| MA0048.1 | 0.353763 |
| MA0050.1 | 0.845669 |
| MA0051.1 | 0.973068 |
| MA0052.1 | 1.29825 |
| MA0055.1 | 1.06076 |
| MA0056.1 | 0 |
| MA0057.1 | 0.896032 |
| MA0058.1 | 0.690848 |
| MA0059.1 | 0.705317 |
| MA0060.1 | 0.502699 |
| MA0061.1 | 0.5406 |
| MA0063.1 | 0 |
| MA0066.1 | 0.951196 |
| MA0067.1 | 1.63197 |
| MA0068.1 | 0.343188 |
| MA0069.1 | 1.29861 |
| MA0070.1 | 1.28847 |
| MA0071.1 | 0.844726 |
| MA0072.1 | 1.2796 |
| MA0073.1 | 0.00834468 |
| MA0074.1 | 0.911576 |
| MA0076.1 | 0.657929 |
| MA0077.1 | 1.2569 |
| MA0078.1 | 1.0091 |
| MA0081.1 | 1.73701 |
| MA0083.1 | 1.37668 |
| MA0084.1 | 1.96428 |
| MA0087.1 | 1.33189 |
| MA0088.1 | 0.27999 |
| MA0089.1 | 0 |
| MA0090.1 | 0.762482 |
| MA0091.1 | 0.816659 |
| MA0092.1 | 0.762845 |
| MA0093.1 | 0.62555 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.89873 |
| MA0101.1 | 0.71579 |
| MA0103.1 | 0.647985 |
| MA0105.1 | 1.04599 |
| MA0106.1 | 1.01755 |
| MA0107.1 | 0.640607 |
| MA0108.2 | 1.10817 |
| MA0109.1 | 0 |
| MA0111.1 | 0.778753 |
| MA0113.1 | 0.986839 |
| MA0114.1 | 0.537669 |
| MA0115.1 | 1.38041 |
| MA0116.1 | 0.602598 |
| MA0117.1 | 1.34691 |
| MA0119.1 | 0.716476 |
| MA0122.1 | 1.36752 |
| MA0124.1 | 1.57762 |
| MA0125.1 | 1.5017 |
| MA0130.1 | 0 |
| MA0131.1 | 1.07881 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.4152 |
| MA0136.1 | 0.933582 |
| MA0139.1 | 1.16863 |
| MA0140.1 | 0.898603 |
| MA0141.1 | 0.671467 |
| MA0142.1 | 1.16183 |
| MA0143.1 | 1.00467 |
| MA0144.1 | 0.541532 |
| MA0145.1 | 0.794492 |
| MA0146.1 | 0.900029 |
| MA0147.1 | 0.556853 |
| MA0148.1 | 0.820161 |
| MA0149.1 | 0.722227 |
| MA0062.2 | 1.06145 |
| MA0035.2 | 0.903829 |
| MA0039.2 | 0.40695 |
| MA0138.2 | 1.07027 |
| MA0002.2 | 3.03802 |
| MA0137.2 | 0.668025 |
| MA0104.2 | 0.48458 |
| MA0047.2 | 0.962424 |
| MA0112.2 | 0.29236 |
| MA0065.2 | 0.79573 |
| MA0150.1 | 0.784464 |
| MA0151.1 | 0 |
| MA0152.1 | 0.962542 |
| MA0153.1 | 1.43238 |
| MA0154.1 | 0.35067 |
| MA0155.1 | 0.312898 |
| MA0156.1 | 0.656895 |
| MA0157.1 | 1.12772 |
| MA0158.1 | 0 |
| MA0159.1 | 0.569393 |
| MA0160.1 | 0.823568 |
| MA0161.1 | 0 |
| MA0162.1 | 0.166722 |
| MA0163.1 | 0.157796 |
| MA0164.1 | 0.933981 |
| MA0080.2 | 1.54848 |
| MA0018.2 | 0.944669 |
| MA0099.2 | 1.06348 |
| MA0079.2 | 0.0831329 |
| MA0102.2 | 2.01714 |
| MA0258.1 | 0.520639 |
| MA0259.1 | 0.543506 |
| MA0442.1 | 0 |
