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Coexpression cluster:C2995

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Full id: C2995_occipital_brain_middle_parietal_medial_hippocampus_amygdala



Phase1 CAGE Peaks

Hg19::chr10:14248805..14248809,-p@chr10:14248805..14248809
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Hg19::chr10:14358505..14358508,-p@chr10:14358505..14358508
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Hg19::chr11:133280516..133280530,-p@chr11:133280516..133280530
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.55e-7956
neural rod1.55e-7956
future spinal cord1.55e-7956
neural keel1.55e-7956
regional part of nervous system1.30e-7553
regional part of brain1.30e-7553
central nervous system1.78e-7481
telencephalon1.39e-7334
brain grey matter1.60e-7334
gray matter1.60e-7334
cerebral hemisphere3.96e-7332
regional part of forebrain4.82e-6941
forebrain4.82e-6941
anterior neural tube4.82e-6941
future forebrain4.82e-6941
regional part of telencephalon1.43e-6732
brain5.09e-6768
future brain5.09e-6768
nervous system3.90e-6689
regional part of cerebral cortex7.33e-6522
neocortex5.94e-5820
cerebral cortex1.05e-5625
pallium1.05e-5625
neural plate1.62e-5482
presumptive neural plate1.62e-5482
neurectoderm2.35e-5486
pre-chordal neural plate3.75e-4461
ecto-epithelium5.01e-41104
adult organism2.11e-34114
ectoderm-derived structure4.01e-33171
ectoderm4.01e-33171
presumptive ectoderm4.01e-33171
structure with developmental contribution from neural crest2.82e-32132
organ system subdivision4.69e-23223
gyrus2.37e-216
tube4.68e-19192
limbic system2.03e-185
basal ganglion2.17e-189
nuclear complex of neuraxis2.17e-189
aggregate regional part of brain2.17e-189
collection of basal ganglia2.17e-189
cerebral subcortex2.17e-189
parietal lobe2.18e-185
temporal lobe4.80e-186
neural nucleus7.61e-189
nucleus of brain7.61e-189
corpus striatum1.95e-144
striatum1.95e-144
ventral part of telencephalon1.95e-144
future corpus striatum1.95e-144
brainstem1.91e-136
anatomical cluster2.06e-13373
anatomical conduit2.45e-13240
posterior neural tube1.47e-1215
chordal neural plate1.47e-1215
telencephalic nucleus2.66e-127
occipital lobe6.29e-125
frontal cortex1.17e-113
caudate-putamen3.44e-113
dorsal striatum3.44e-113
pons2.14e-103
organ part4.39e-10218
segmental subdivision of hindbrain3.47e-0912
hindbrain3.47e-0912
presumptive hindbrain3.47e-0912
multi-tissue structure1.40e-08342
Ammon's horn1.48e-082
lobe parts of cerebral cortex1.48e-082
hippocampal formation1.48e-082
limbic lobe1.48e-082
epithelium1.83e-08306
segmental subdivision of nervous system1.97e-0813
middle frontal gyrus2.36e-082
amygdala2.54e-082
cell layer2.70e-08309
middle temporal gyrus3.14e-082
caudate nucleus4.46e-082
future caudate nucleus4.46e-082
locus ceruleus1.34e-072
brainstem nucleus1.34e-072
hindbrain nucleus1.34e-072


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0471418
MA0004.10.826076
MA0006.10.639288
MA0007.10.804807
MA0009.11.3275
MA0014.10.118426
MA0017.10.686276
MA0019.10.990656
MA0024.11.21731
MA0025.11.46617
MA0027.12.95767
MA0028.10.658629
MA0029.11.23771
MA0030.11.22561
MA0031.11.15713
MA0038.12.16573
MA0040.11.24388
MA0041.10.847069
MA0042.10.810843
MA0043.11.32783
MA0046.11.31611
MA0048.10.341392
MA0050.10.81185
MA0051.10.936307
MA0052.11.24796
MA0055.10.190716
MA0056.10
MA0057.10.333427
MA0058.10.716037
MA0059.10.714521
MA0060.11.23283
MA0061.10.456531
MA0063.10
MA0066.10.941452
MA0067.11.65513
MA0068.11.04561
MA0069.11.31207
MA0070.11.30033
MA0071.10.897953
MA0072.11.29561
MA0073.10.0185922
MA0074.10.935474
MA0076.10.734647
MA0077.11.28751
MA0078.11.04495
MA0081.10.714712
MA0083.11.33535
MA0084.11.84562
MA0087.11.29304
MA0088.10.257905
MA0089.10
MA0090.10.751469
MA0091.10.829044
MA0092.10.785956
MA0093.10.642957
MA0095.10
MA0098.10
MA0100.10.956299
MA0101.10.646932
MA0103.10.628063
MA0105.10.31555
MA0106.10.986396
MA0107.10.556367
MA0108.21.15387
MA0109.10
MA0111.10.767139
MA0113.11.00436
MA0114.10.549955
MA0115.11.57693
MA0116.10.560723
MA0117.11.36676
MA0119.10.695578
MA0122.11.39371
MA0124.11.53432
MA0125.11.44766
MA0130.10
MA0131.11.06461
MA0132.10
MA0133.10
MA0135.11.35921
MA0136.10.948776
MA0139.10.440097
MA0140.10.894983
MA0141.10.712476
MA0142.11.12317
MA0143.11.00455
MA0144.10.531867
MA0145.10.273764
MA0146.10.107247
MA0147.10.565108
MA0148.10.854239
MA0149.10.884158
MA0062.20.449458
MA0035.20.894194
MA0039.20.0526989
MA0138.21.04628
MA0002.20.476938
MA0137.20.666381
MA0104.20.491226
MA0047.20.973066
MA0112.20.264678
MA0065.20.277623
MA0150.10.744617
MA0151.10
MA0152.10.902317
MA0153.11.43021
MA0154.10.312019
MA0155.10.256269
MA0156.10.669101
MA0157.11.09377
MA0158.10
MA0159.10.565904
MA0160.10.871361
MA0161.10
MA0162.10.149099
MA0163.10.122425
MA0164.12.32251
MA0080.20.643061
MA0018.20.987913
MA0099.20.902716
MA0079.20.00160703
MA0102.21.88331
MA0258.10.519674
MA0259.10.575594
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.