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Coexpression cluster:C86

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Full id: C86_colon_carcinoid_small_neuroectodermal_giant_large_neuroepithelioma



Phase1 CAGE Peaks

Hg19::chr10:2328652..2328660,+p@chr10:2328652..2328660
+
Hg19::chr10:7144649..7144656,-p@chr10:7144649..7144656
-
Hg19::chr10:72303802..72303817,+p@chr10:72303802..72303817
+
Hg19::chr11:90181710..90181723,+p@chr11:90181710..90181723
+
Hg19::chr12:27932408..27932428,+p17@KLHDC5
Hg19::chr12:65277536..65277559,+p1@FLJ41278
Hg19::chr12:65277574..65277589,+p2@FLJ41278
Hg19::chr12:65447288..65447294,+p@chr12:65447288..65447294
+
Hg19::chr12:65466870..65466883,-p@chr12:65466870..65466883
-
Hg19::chr12:65466889..65466894,-p@chr12:65466889..65466894
-
Hg19::chr12:68155058..68155064,-p@chr12:68155058..68155064
-
Hg19::chr12:77730114..77730120,-p@chr12:77730114..77730120
-
Hg19::chr13:110258158..110258170,-p@chr13:110258158..110258170
-
Hg19::chr13:28541425..28541439,-p@chr13:28541425..28541439
-
Hg19::chr13:28541442..28541451,-p@chr13:28541442..28541451
-
Hg19::chr13:28541455..28541475,-p7@CDX2
Hg19::chr13:28541477..28541493,-p6@CDX2
Hg19::chr13:28542963..28542973,-p1@CU677005
Hg19::chr13:28543253..28543276,-p5@CDX2
Hg19::chr13:28543285..28543314,-p2@CDX2
Hg19::chr13:28543316..28543329,-p4@CDX2
Hg19::chr13:28543388..28543406,-p3@CDX2
Hg19::chr13:28543409..28543420,-p8@CDX2
Hg19::chr13:28543431..28543487,-p1@CDX2
Hg19::chr13:35865840..35865849,-p@chr13:35865840..35865849
-
Hg19::chr13:48703799..48703838,-p@chr13:48703799..48703838
-
Hg19::chr13:54830821..54830841,+p@chr13:54830821..54830841
+
Hg19::chr13:99661014..99661016,-p@chr13:99661014..99661016
-
Hg19::chr13:99661025..99661033,-p@chr13:99661025..99661033
-
Hg19::chr14:26793376..26793387,-p@chr14:26793376..26793387
-
Hg19::chr14:26793415..26793426,-p@chr14:26793415..26793426
-
Hg19::chr14:76289395..76289406,+p@chr14:76289395..76289406
+
Hg19::chr15:45950466..45950474,+p@chr15:45950466..45950474
+
Hg19::chr15:45950495..45950505,+p@chr15:45950495..45950505
+
Hg19::chr15:45950558..45950561,+p@chr15:45950558..45950561
+
Hg19::chr15:71524066..71524082,-p@chr15:71524066..71524082
-
Hg19::chr15:89755108..89755155,-p@chr15:89755108..89755155
-
Hg19::chr16:50278603..50278615,+p@chr16:50278603..50278615
+
Hg19::chr16:50278618..50278635,+p@chr16:50278618..50278635
+
Hg19::chr16:50278652..50278662,+p@chr16:50278652..50278662
+
Hg19::chr16:53671764..53671771,-p@chr16:53671764..53671771
-
Hg19::chr16:55344418..55344442,+p@chr16:55344418..55344442
+
Hg19::chr17:39123197..39123201,-p2@KRT39
Hg19::chr17:39556122..39556149,+p@chr17:39556122..39556149
+
Hg19::chr17:50822847..50822851,-p@chr17:50822847..50822851
-
Hg19::chr17:50906109..50906121,-p@chr17:50906109..50906121
-
Hg19::chr17:50906130..50906141,-p@chr17:50906130..50906141
-
Hg19::chr17:63557759..63557774,-p4@AXIN2
Hg19::chr17:63771073..63771114,-p@chr17:63771073..63771114
-
Hg19::chr18:13542298..13542308,+p@chr18:13542298..13542308
+
Hg19::chr18:28720966..28720970,+p@chr18:28720966..28720970
+
Hg19::chr18:28860939..28860953,-p@chr18:28860939..28860953
-
Hg19::chr18:30792468..30792481,-p@chr18:30792468..30792481
-
Hg19::chr18:39550015..39550034,+p@chr18:39550015..39550034
+
Hg19::chr18:52421471..52421476,+p@chr18:52421471..52421476
+
Hg19::chr18:53252911..53252918,-p106@TCF4
Hg19::chr1:118656031..118656034,-p@chr1:118656031..118656034
-
Hg19::chr1:118656052..118656062,-p@chr1:118656052..118656062
-
Hg19::chr1:118658073..118658082,-p@chr1:118658073..118658082
-
Hg19::chr1:119837610..119837621,+p@chr1:119837610..119837621
+
Hg19::chr1:119837632..119837659,+p@chr1:119837632..119837659
+
Hg19::chr1:119837700..119837705,+p@chr1:119837700..119837705
+
Hg19::chr1:119869755..119869768,-p2@ENST00000457719
Hg19::chr1:119869778..119869800,-p3@ENST00000457719
Hg19::chr1:119869827..119869830,-p7@ENST00000457719
Hg19::chr1:119869834..119869845,-p4@ENST00000457719
Hg19::chr1:119869846..119869867,-p1@ENST00000457719
Hg19::chr1:163338283..163338286,+p@chr1:163338283..163338286
+
Hg19::chr1:198324710..198324721,+p@chr1:198324710..198324721
+
Hg19::chr1:198324725..198324738,+p@chr1:198324725..198324738
+
Hg19::chr1:198324742..198324745,+p@chr1:198324742..198324745
+
Hg19::chr1:219739282..219739288,-p@chr1:219739282..219739288
-
Hg19::chr1:47183812..47183848,-p3@KIAA0494
Hg19::chr1:47183850..47183861,-p12@KIAA0494
Hg19::chr1:47183863..47183866,-p20@KIAA0494
Hg19::chr1:55404829..55404833,-p@chr1:55404829..55404833
-
Hg19::chr1:78621016..78621042,+p@chr1:78621016..78621042
+
Hg19::chr1:93128331..93128338,-p@chr1:93128331..93128338
-
Hg19::chr1:93128346..93128356,-p@chr1:93128346..93128356
-
Hg19::chr20:10092229..10092265,-p@chr20:10092229..10092265
-
Hg19::chr20:22034809..22034813,+p1@ENST00000449427
Hg19::chr21:37143915..37143924,-p@chr21:37143915..37143924
-
Hg19::chr2:109223595..109223610,+p19@LIMS1
Hg19::chr2:127711416..127711419,+p@chr2:127711416..127711419
+
Hg19::chr2:127711472..127711475,+p@chr2:127711472..127711475
+
Hg19::chr2:148148505..148148515,-p@chr2:148148505..148148515
-
Hg19::chr2:159306961..159306975,+p@chr2:159306961..159306975
+
Hg19::chr2:159306978..159306987,+p@chr2:159306978..159306987
+
Hg19::chr2:163302780..163302789,-p@chr2:163302780..163302789
-
Hg19::chr2:163302793..163302800,-p@chr2:163302793..163302800
-
Hg19::chr2:165424899..165424913,-p6@GRB14
Hg19::chr2:171565187..171565198,-p@chr2:171565187..171565198
-
Hg19::chr2:172822844..172822852,+p@chr2:172822844..172822852
+
Hg19::chr2:191230499..191230510,+p@chr2:191230499..191230510
+
Hg19::chr2:19707156..19707203,+p@chr2:19707156..19707203
+
Hg19::chr2:205036975..205037009,-p@chr2:205036975..205037009
-
Hg19::chr2:205099653..205099688,-p1@ENST00000419860
Hg19::chr2:205099700..205099708,-p2@ENST00000419860
Hg19::chr2:225543308..225543324,+p@chr2:225543308..225543324
+
Hg19::chr2:50452322..50452343,+p@chr2:50452322..50452343
+
Hg19::chr2:66794374..66794383,+p@chr2:66794374..66794383
+
Hg19::chr2:66794389..66794398,+p@chr2:66794389..66794398
+
Hg19::chr2:740879..740895,+p@chr2:740879..740895
+
Hg19::chr2:740910..740923,+p@chr2:740910..740923
+
Hg19::chr2:747715..747728,+p@chr2:747715..747728
+
Hg19::chr3:140054665..140054678,-p@chr3:140054665..140054678
-
Hg19::chr3:140054724..140054735,-p@chr3:140054724..140054735
-
Hg19::chr3:148164659..148164667,-p@chr3:148164659..148164667
-
Hg19::chr3:148164872..148164919,-p@chr3:148164872..148164919
-
Hg19::chr3:148165064..148165071,-p@chr3:148165064..148165071
-
Hg19::chr3:156822661..156822696,-p@chr3:156822661..156822696
-
Hg19::chr3:171088092..171088113,-p@chr3:171088092..171088113
-
Hg19::chr3:185772095..185772119,-p@chr3:185772095..185772119
-
Hg19::chr3:185823495..185823511,-p12@ETV5
Hg19::chr3:185823573..185823578,-p26@ETV5
Hg19::chr3:191000073..191000089,-p5@UTS2D
Hg19::chr3:191000091..191000117,-p1@UTS2D
Hg19::chr3:193356854..193356864,+p@chr3:193356854..193356864
+
Hg19::chr3:24797750..24797759,-p@chr3:24797750..24797759
-
Hg19::chr3:24797832..24797838,-p@chr3:24797832..24797838
-
Hg19::chr3:66354424..66354472,+p@chr3:66354424..66354472
+
Hg19::chr4:138999555..138999575,-p@chr4:138999555..138999575
-
Hg19::chr4:157174023..157174034,+p@chr4:157174023..157174034
+
Hg19::chr4:157174062..157174071,+p@chr4:157174062..157174071
+
Hg19::chr4:157174075..157174084,+p@chr4:157174075..157174084
+
Hg19::chr4:157174108..157174136,+p@chr4:157174108..157174136
+
Hg19::chr4:157174324..157174332,+p@chr4:157174324..157174332
+
Hg19::chr4:169552329..169552340,+p34@PALLD
Hg19::chr4:169559850..169559856,-p@chr4:169559850..169559856
-
Hg19::chr4:71222797..71222807,+p@chr4:71222797..71222807
+
Hg19::chr5:121814761..121814765,-p4@ENST00000503529
Hg19::chr5:121814774..121814793,-p1@ENST00000503529
p1@ENST00000510972
p1@uc003ktb.1
Hg19::chr5:57619538..57619575,-p@chr5:57619538..57619575
-
Hg19::chr5:71987749..71987774,-p@chr5:71987749..71987774
-
Hg19::chr5:97747048..97747059,+p@chr5:97747048..97747059
+
Hg19::chr6:104674708..104674749,-p@chr6:104674708..104674749
-
Hg19::chr6:372660..372670,-p@chr6:372660..372670
-
Hg19::chr6:5491056..5491061,+p@chr6:5491056..5491061
+
Hg19::chr6:5491081..5491106,+p@chr6:5491081..5491106
+
Hg19::chr6:8389087..8389116,-p@chr6:8389087..8389116
-
Hg19::chr6:8389389..8389429,-p@chr6:8389389..8389429
-
Hg19::chr6:91774965..91774974,+p@chr6:91774965..91774974
+
Hg19::chr7:110230449..110230452,-p@chr7:110230449..110230452
-
Hg19::chr7:110230549..110230565,-p@chr7:110230549..110230565
-
Hg19::chr7:138064518..138064531,-p@chr7:138064518..138064531
-
Hg19::chr7:141499716..141499722,+p@chr7:141499716..141499722
+
Hg19::chr7:30499737..30499761,+p@chr7:30499737..30499761
+
Hg19::chr7:80253387..80253419,+p4@CD36
Hg19::chr7:87049573..87049608,-p@chr7:87049573..87049608
-
Hg19::chr7:87232406..87232409,-p@chr7:87232406..87232409
-
Hg19::chr7:87232419..87232430,-p@chr7:87232419..87232430
-
Hg19::chr7:87232440..87232448,-p@chr7:87232440..87232448
-
Hg19::chr7:89797154..89797172,+p9@STEAP2
Hg19::chr8:107630340..107630359,+p12@OXR1
Hg19::chr8:107667666..107667673,+p@chr8:107667666..107667673
+
Hg19::chr8:127438794..127438800,+p@chr8:127438794..127438800
+
Hg19::chr8:127440115..127440120,+p@chr8:127440115..127440120
+
Hg19::chr8:127445866..127445873,+p@chr8:127445866..127445873
+
Hg19::chr8:127449395..127449424,+p@chr8:127449395..127449424
+
Hg19::chr8:127450087..127450092,+p@chr8:127450087..127450092
+
Hg19::chr8:127472815..127472822,+p@chr8:127472815..127472822
+
Hg19::chr8:127508635..127508640,+p@chr8:127508635..127508640
+
Hg19::chr8:127566297..127566307,-p@chr8:127566297..127566307
-
Hg19::chr8:127567083..127567087,-p6@FAM84B
Hg19::chr8:127568784..127568794,+p6@ENST00000524320
Hg19::chr8:127568810..127568821,+p2@ENST00000524320
Hg19::chr8:127569936..127570038,-p3@FAM84B
Hg19::chr8:127570603..127570648,-p1@FAM84B
Hg19::chr8:127570656..127570667,-p5@FAM84B
Hg19::chr8:127570676..127570690,-p4@FAM84B
Hg19::chr8:127570706..127570729,-p2@FAM84B
Hg19::chr8:127681013..127681042,-p@chr8:127681013..127681042
-
Hg19::chr8:127817393..127817400,+p@chr8:127817393..127817400
+
Hg19::chr8:127836882..127836885,+p@chr8:127836882..127836885
+
Hg19::chr8:127881773..127881775,+p@chr8:127881773..127881775
+
Hg19::chr8:128118744..128118753,-p@chr8:128118744..128118753
-
Hg19::chr8:128259602..128259609,-p@chr8:128259602..128259609
-
Hg19::chr8:128260156..128260173,+p@chr8:128260156..128260173
+
Hg19::chr8:128269499..128269507,-p@chr8:128269499..128269507
-
Hg19::chr8:128415915..128415922,+p@chr8:128415915..128415922
+
Hg19::chr8:128415944..128415958,+p@chr8:128415944..128415958
+
Hg19::chr8:128418204..128418209,-p@chr8:128418204..128418209
-
Hg19::chr8:128418747..128418756,-p@chr8:128418747..128418756
-
Hg19::chr8:128418776..128418790,-p@chr8:128418776..128418790
-
Hg19::chr8:128418828..128418839,-p@chr8:128418828..128418839
-
Hg19::chr8:128419359..128419367,-p@chr8:128419359..128419367
-
Hg19::chr8:128691603..128691614,-p@chr8:128691603..128691614
-
Hg19::chr8:128747729..128747748,+p14@MYC
Hg19::chr8:128747757..128747800,+p7@MYC
Hg19::chr8:128806214..128806243,+p@chr8:128806214..128806243
+
Hg19::chr8:128806244..128806266,+p@chr8:128806244..128806266
+
Hg19::chr8:128806307..128806348,+p9@PVT1
Hg19::chr8:128806753..128806815,+p1@PVT1
Hg19::chr8:128807259..128807281,+p@chr8:128807259..128807281
+
Hg19::chr8:128807937..128807941,+p20@PVT1
Hg19::chr8:128900203..128900207,+p@chr8:128900203..128900207
+
Hg19::chr8:128908624..128908634,+p@chr8:128908624..128908634
+
Hg19::chr8:128908649..128908661,+p@chr8:128908649..128908661
+
Hg19::chr8:128908678..128908696,+p@chr8:128908678..128908696
+
Hg19::chr8:128909509..128909531,+p@chr8:128909509..128909531
+
Hg19::chr8:128909572..128909583,+p@chr8:128909572..128909583
+
Hg19::chr8:128909594..128909613,+p@chr8:128909594..128909613
+
Hg19::chr8:128909653..128909681,+p@chr8:128909653..128909681
+
Hg19::chr8:128910010..128910030,+p@chr8:128910010..128910030
+
Hg19::chr8:130284717..130284721,-p@chr8:130284717..130284721
-
Hg19::chr8:39792165..39792176,+p1@IDO2
Hg19::chr8:39792182..39792188,+p14@IDO2
Hg19::chr9:104610923..104610939,-p@chr9:104610923..104610939
-
Hg19::chr9:120162674..120162685,-p@chr9:120162674..120162685
-
Hg19::chr9:125898916..125898941,-p14@STRBP
Hg19::chr9:95166976..95166979,-p8@OGN
Hg19::chr9:97766409..97766428,+p20@C9orf3
Hg19::chr9:98505341..98505348,+p@chr9:98505341..98505348
+
Hg19::chrX:138909080..138909093,-p@chrX:138909080..138909093
-
Hg19::chrX:138914394..138914405,-p10@ATP11C
Hg19::chrX:42162203..42162241,+p@chrX:42162203..42162241
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

p.valueFDRnGenesnPathwayName
2.05892215321743e-050.006516488614933166740TGF beta receptor down reg. targets (Netpath):NetPath_7
1.47712332636225e-060.000935019065587306328Wnt down reg. targets (Netpath):NetPath_8



Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
epithelial cell1.04e-35254
endodermal cell8.42e-1159
endo-epithelial cell1.70e-0943
squamous epithelial cell1.51e-0762
Uber Anatomy
Ontology termp-valuen
endoderm-derived structure1.22e-15169
endoderm1.22e-15169
presumptive endoderm1.22e-15169
subdivision of digestive tract5.74e-15129
endodermal part of digestive tract5.74e-15129
digestive system4.05e-14155
digestive tract4.05e-14155
primitive gut4.05e-14155
mixed endoderm/mesoderm-derived structure2.31e-12130
immaterial anatomical entity2.58e-12126
trunk region element4.64e-12107
anatomical space1.17e-11104
gastrointestinal system1.43e-1035
foregut1.63e-1098
organ part3.72e-09219
endo-epithelium1.67e-0882
intestine3.24e-0827
subdivision of trunk8.28e-08113
primordium8.90e-08168
anatomical cavity1.41e-0770
lung2.90e-0722
respiratory tube2.90e-0722
respiration organ2.90e-0722
pair of lungs2.90e-0722
lung primordium2.90e-0722
lung bud2.90e-0722
respiratory system8.88e-0772
Disease
Ontology termp-valuen
cell type cancer1.95e-29143
cancer1.66e-26235
carcinoma1.98e-26106
disease of cellular proliferation6.81e-25239
adenocarcinoma7.03e-1025
organ system cancer3.31e-09137
squamous cell carcinoma3.76e-0814
respiratory system cancer6.11e-0716


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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