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MCL coexpression mm9:492

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:74040750..74040762,-p3@4930447C04Rik
Mm9::chr17:86012566..86012578,+p10@Six3
Mm9::chr17:86012772..86012825,+p4@Six3
Mm9::chr17:86014142..86014152,-p@chr17:86014142..86014152
-
Mm9::chr17:86020115..86020128,+p2@Six3
Mm9::chr17:86020137..86020149,+p5@Six3
Mm9::chr17:86020156..86020183,+p1@Six3
Mm9::chr17:86020186..86020195,+p9@Six3
Mm9::chr17:86020336..86020352,+p8@Six3
Mm9::chr17:86020357..86020366,+p11@Six3
Mm9::chr17:86023259..86023303,+p@chr17:86023259..86023303
+
Mm9::chr17:86023309..86023375,+p@chr17:86023309..86023375
+
Mm9::chr17:86023549..86023562,+p@chr17:86023549..86023562
+
Mm9::chr17:86028449..86028473,+p@chr17:86028449..86028473
+
Mm9::chr2:162948383..162948429,+p1@uc008nsn.1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0030178negative regulation of Wnt receptor signaling pathway0.0249091473547727
GO:0003705RNA polymerase II transcription factor activity, enhancer binding0.0249091473547727
GO:0030111regulation of Wnt receptor signaling pathway0.0249091473547727



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)2.87e-0823
neuroblast (sensu Vertebrata)2.87e-0823
neural cell6.87e-0743

Uber Anatomy
Ontology termp-valuen
pre-chordal neural plate7.92e-3449
neurectoderm4.60e-2564
neural plate4.60e-2564
presumptive neural plate4.60e-2564
anterior neural tube7.82e-2140
ecto-epithelium1.12e-2073
ectoderm-derived structure1.72e-2095
ectoderm1.72e-2095
presumptive ectoderm1.72e-2095
regional part of forebrain1.15e-1939
forebrain1.15e-1939
future forebrain1.15e-1939
regional part of brain1.11e-1846
brain4.07e-1847
future brain4.07e-1847
regional part of nervous system1.43e-1754
diencephalon1.96e-1610
future diencephalon1.96e-1610
neural tube1.27e-1552
neural rod1.27e-1552
future spinal cord1.27e-1552
neural keel1.27e-1552
eye1.86e-159
camera-type eye1.86e-159
simple eye1.86e-159
immature eye1.86e-159
ocular region1.86e-159
visual system1.86e-159
face1.86e-159
optic cup1.86e-159
optic vesicle1.86e-159
eye primordium1.86e-159
central nervous system2.45e-1573
nervous system1.11e-1475
structure with developmental contribution from neural crest2.77e-1492
pituitary gland9.37e-148
gland of diencephalon9.37e-148
neuroendocrine gland9.37e-148
subdivision of head3.27e-1211
sense organ5.35e-1112
sensory system5.35e-1112
entire sense organ system5.35e-1112
head5.66e-1013
ectodermal placode5.66e-1013
basal ganglion6.28e-098
nuclear complex of neuraxis6.28e-098
aggregate regional part of brain6.28e-098
collection of basal ganglia6.28e-098
cerebral subcortex6.28e-098
corpus striatum1.96e-085
striatum1.96e-085
ventral part of telencephalon1.96e-085
future corpus striatum1.96e-085
brain grey matter3.68e-0829
regional part of telencephalon3.68e-0829
telencephalon3.68e-0829
Ammon's horn2.09e-077
lobe parts of cerebral cortex2.09e-077
hippocampal formation2.09e-077
limbic system2.09e-077
limbic lobe2.09e-077


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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