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Coexpression cluster:C648

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Full id: C648_caudate_corpus_diencephalon_medulla_occipital_nucleus_thalamus



Phase1 CAGE Peaks

Hg19::chr10:1588921..1588932,+p@chr10:1588921..1588932
+
Hg19::chr10:73479518..73479527,-p5@C10orf105
Hg19::chr10:97236225..97236232,-p@chr10:97236225..97236232
-
Hg19::chr14:33926303..33926307,-p@chr14:33926303..33926307
-
Hg19::chr14:36462819..36462832,+p@chr14:36462819..36462832
+
Hg19::chr14:36462843..36462863,+p@chr14:36462843..36462863
+
Hg19::chr17:72823919..72823924,-p@chr17:72823919..72823924
-
Hg19::chr18:24521807..24521809,+p@chr18:24521807..24521809
+
Hg19::chr2:115219219..115219230,+p7@DPP10
Hg19::chr2:232548018..232548022,-p@chr2:232548018..232548022
-
Hg19::chr5:60927228..60927236,-p3@BC032909
p3@BC032910
Hg19::chr9:87605893..87605904,+p@chr9:87605893..87605904
+
Hg19::chr9:87655746..87655753,-p@chr9:87655746..87655753
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004274dipeptidyl-peptidase IV activity0.0041014168530947
GO:0016806dipeptidyl-peptidase and tripeptidyl-peptidase activity0.0041014168530947
GO:0008239dipeptidyl-peptidase activity0.0041014168530947
GO:0008238exopeptidase activity0.0302749322971859
GO:0008236serine-type peptidase activity0.0406903724635975
GO:0017171serine hydrolase activity0.0406903724635975



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube8.77e-11357
neural rod8.77e-11357
future spinal cord8.77e-11357
neural keel8.77e-11357
regional part of brain4.49e-9559
central nervous system7.61e-9482
regional part of forebrain5.20e-9141
forebrain5.20e-9141
future forebrain5.20e-9141
brain2.46e-8969
future brain2.46e-8969
anterior neural tube1.25e-8842
neural plate5.52e-8686
presumptive neural plate5.52e-8686
regional part of nervous system3.69e-8294
nervous system3.69e-8294
neurectoderm1.47e-8190
telencephalon9.64e-7434
gray matter4.28e-7334
brain grey matter4.28e-7334
regional part of telencephalon4.75e-7133
cerebral hemisphere2.03e-6832
pre-chordal neural plate2.46e-6761
adult organism3.14e-57115
anterior region of body3.91e-54129
craniocervical region3.91e-54129
head4.96e-51123
cerebral cortex1.71e-5025
pallium1.71e-5025
regional part of cerebral cortex1.41e-4822
neocortex2.78e-4320
ectoderm-derived structure4.39e-43169
ectoderm9.24e-42173
presumptive ectoderm9.24e-42173
tube2.32e-26194
basal ganglion4.38e-249
nuclear complex of neuraxis4.38e-249
aggregate regional part of brain4.38e-249
collection of basal ganglia4.38e-249
cerebral subcortex4.38e-249
posterior neural tube5.96e-2415
chordal neural plate5.96e-2415
nucleus of brain9.30e-249
neural nucleus9.30e-249
telencephalic nucleus4.40e-197
epithelium8.86e-19309
anatomical conduit1.39e-18241
cell layer1.87e-18312
diencephalon4.22e-187
future diencephalon4.22e-187
segmental subdivision of hindbrain4.89e-1712
hindbrain4.89e-1712
presumptive hindbrain4.89e-1712
anatomical cluster6.19e-17286
brainstem1.41e-168
gyrus2.47e-166
temporal lobe2.52e-167
segmental subdivision of nervous system1.40e-1513
limbic system1.06e-145
organism subdivision1.92e-14365
organ part4.19e-14219
parietal lobe9.28e-145
corpus striatum5.89e-124
striatum5.89e-124
ventral part of telencephalon5.89e-124
future corpus striatum5.89e-124
gland of diencephalon3.00e-104
neuroendocrine gland3.00e-104
regional part of metencephalon4.32e-109
metencephalon4.32e-109
future metencephalon4.32e-109
medulla oblongata1.41e-093
myelencephalon1.41e-093
future myelencephalon1.41e-093
occipital lobe2.92e-095
caudate-putamen3.07e-093
dorsal striatum3.07e-093
spinal cord5.01e-093
middle temporal gyrus6.05e-093
pons7.50e-093
brainstem nucleus8.81e-093
organ1.11e-08511
multi-tissue structure1.72e-08347
Ammon's horn5.80e-072
lobe parts of cerebral cortex5.80e-072
hippocampal formation5.80e-072
limbic lobe5.80e-072
caudate nucleus6.31e-072
future caudate nucleus6.31e-072
dorsal plus ventral thalamus7.91e-072


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.