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Coexpression cluster:C1567

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Full id: C1567_Neural_pituitary_caudate_spinal_Neurons_parietal_putamen



Phase1 CAGE Peaks

Hg19::chr10:123951927..123951952,+p17@TACC2
Hg19::chr10:123951957..123951980,+p18@TACC2
Hg19::chr17:61194527..61194561,+p@chr17:61194527..61194561
+
Hg19::chr17:61194578..61194599,+p@chr17:61194578..61194599
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Hg19::chr17:61194620..61194635,+p@chr17:61194620..61194635
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube2.89e-7957
neural rod2.89e-7957
future spinal cord2.89e-7957
neural keel2.89e-7957
central nervous system5.34e-7682
regional part of nervous system1.52e-7394
nervous system1.52e-7394
regional part of brain3.13e-6659
regional part of forebrain2.51e-6441
forebrain2.51e-6441
future forebrain2.51e-6441
brain4.76e-6369
future brain4.76e-6369
anterior neural tube1.75e-6242
neural plate1.17e-5686
presumptive neural plate1.17e-5686
adult organism1.25e-53115
neurectoderm2.69e-5390
gray matter5.27e-5334
brain grey matter5.27e-5334
telencephalon5.45e-5334
regional part of telencephalon2.30e-5133
cerebral hemisphere5.19e-5032
pre-chordal neural plate4.56e-4561
ectoderm-derived structure3.83e-40169
ectoderm1.07e-38173
presumptive ectoderm1.07e-38173
cerebral cortex2.16e-3825
pallium2.16e-3825
head2.98e-37123
anterior region of body4.99e-36129
craniocervical region4.99e-36129
regional part of cerebral cortex3.48e-3422
neocortex5.32e-3120
posterior neural tube3.34e-1715
chordal neural plate3.34e-1715
tube4.05e-17194
nucleus of brain8.41e-169
neural nucleus8.41e-169
basal ganglion1.16e-159
nuclear complex of neuraxis1.16e-159
aggregate regional part of brain1.16e-159
collection of basal ganglia1.16e-159
cerebral subcortex1.16e-159
anatomical conduit7.01e-15241
segmental subdivision of nervous system9.74e-1413
telencephalic nucleus8.69e-137
segmental subdivision of hindbrain1.92e-1212
hindbrain1.92e-1212
presumptive hindbrain1.92e-1212
diencephalon2.01e-127
future diencephalon2.01e-127
anatomical cluster7.94e-12286
organ part2.14e-11219
gyrus5.61e-116
organism subdivision3.11e-10365
brainstem3.22e-108
temporal lobe3.77e-107
parietal lobe7.95e-105
occipital lobe1.52e-095
limbic system2.45e-095
epithelium4.36e-09309
organ6.25e-09511
cell layer7.82e-09312
corpus striatum1.85e-084
striatum1.85e-084
ventral part of telencephalon1.85e-084
future corpus striatum1.85e-084
regional part of metencephalon2.82e-089
metencephalon2.82e-089
future metencephalon2.82e-089
embryo5.20e-08612
multi-tissue structure6.98e-08347
gland of diencephalon1.01e-074
neuroendocrine gland1.01e-074
germ layer4.08e-07604
embryonic tissue4.08e-07604
presumptive structure4.08e-07604
epiblast (generic)4.08e-07604
embryonic structure4.64e-07605
developing anatomical structure4.64e-07605
anatomical system8.45e-07625
caudate-putamen8.57e-073
dorsal striatum8.57e-073
anatomical group9.57e-07626


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.