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Coexpression cluster:C2105

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Full id: C2105_parietal_amygdala_thalamus_medial_cerebellum_hippocampus_caudate



Phase1 CAGE Peaks

Hg19::chr11:120746761..120746773,+p@chr11:120746761..120746773
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Hg19::chr14:33197436..33197439,+p@chr14:33197436..33197439
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Hg19::chr5:58149845..58149856,+p@chr5:58149845..58149856
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Hg19::chr8:26486520..26486538,+p@chr8:26486520..26486538
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.13e-7556
neural rod1.13e-7556
future spinal cord1.13e-7556
neural keel1.13e-7556
regional part of nervous system8.32e-7153
regional part of brain8.32e-7153
central nervous system3.72e-6381
brain1.58e-6268
future brain1.58e-6268
regional part of forebrain8.18e-6141
forebrain8.18e-6141
anterior neural tube8.18e-6141
future forebrain8.18e-6141
nervous system4.94e-5989
neural plate1.85e-5282
presumptive neural plate1.85e-5282
neurectoderm4.97e-5186
brain grey matter7.76e-5034
gray matter7.76e-5034
adult organism7.85e-50114
telencephalon1.41e-4934
regional part of telencephalon2.01e-4632
cerebral hemisphere3.36e-4632
pre-chordal neural plate1.02e-4061
ecto-epithelium5.50e-39104
cerebral cortex5.16e-3525
pallium5.16e-3525
regional part of cerebral cortex1.78e-3422
neocortex5.17e-3120
structure with developmental contribution from neural crest1.78e-29132
organ system subdivision5.80e-27223
ectoderm-derived structure9.64e-27171
ectoderm9.64e-27171
presumptive ectoderm9.64e-27171
tube3.74e-17192
basal ganglion3.82e-169
nuclear complex of neuraxis3.82e-169
aggregate regional part of brain3.82e-169
collection of basal ganglia3.82e-169
cerebral subcortex3.82e-169
neural nucleus3.89e-169
nucleus of brain3.89e-169
posterior neural tube1.30e-1515
chordal neural plate1.30e-1515
telencephalic nucleus7.90e-137
anatomical conduit1.16e-12240
diencephalon2.24e-127
future diencephalon2.24e-127
segmental subdivision of hindbrain2.45e-1112
hindbrain2.45e-1112
presumptive hindbrain2.45e-1112
gyrus4.50e-116
brainstem4.82e-116
segmental subdivision of nervous system2.75e-1013
anatomical cluster4.32e-10373
limbic system7.66e-105
parietal lobe1.56e-095
occipital lobe2.17e-095
temporal lobe2.87e-096
epithelium3.92e-08306
regional part of diencephalon5.11e-084
organ part5.25e-08218
corpus striatum6.75e-084
striatum6.75e-084
ventral part of telencephalon6.75e-084
future corpus striatum6.75e-084
cell layer6.77e-08309
gland of diencephalon1.50e-074
neuroendocrine gland1.50e-074
multi-tissue structure2.71e-07342
regional part of metencephalon3.37e-079
metencephalon3.37e-079
future metencephalon3.37e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.