MCL coexpression mm9:345

Phase1 CAGE Peaks

	Short description
Mm9::chr10:127707602..127707633,+	p1@Stat2
Mm9::chr10:43723638..43723704,-	p@chr10:43723638..43723704 -
Mm9::chr11:101309717..101309801,+	p1@Ifi35
Mm9::chr13:58259003..58259050,+	p1@5133401N09Rik
Mm9::chr16:35871458..35871474,-	p1@Parp14
Mm9::chr16:35938971..35938994,-	p2@Dtx3l
Mm9::chr16:35938998..35939024,-	p1@Dtx3l
Mm9::chr16:35939058..35939158,+	p1@Parp9
Mm9::chr17:36169627..36169687,-	p1@C920025E04Rik p1@H2-T23 p1@LOC100505163
Mm9::chr1:133904946..133904974,+	p7@Elk4
Mm9::chr1:58852462..58852483,+	p4@Casp8
Mm9::chr1:58852500..58852511,+	p8@Casp8
Mm9::chr2:166888058..166888105,-	p2@Znfx1
Mm9::chr2:51828449..51828501,-	p1@Nmi
Mm9::chr2:51828510..51828542,-	p2@Nmi
Mm9::chr4:115500666..115500708,+	p1@Mob3c
Mm9::chr5:31999971..32000005,-	p1@Rbks
Mm9::chr6:38304231..38304240,-	p4@Zc3hav1
Mm9::chr6:38304243..38304292,-	p2@Zc3hav1
Mm9::chr6:57530965..57530979,+	p3@Herc6
Mm9::chr6:57530988..57531009,+	p2@Herc6
Mm9::chr8:70018742..70018782,+	p1@Nat2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0003950	NAD+ ADP-ribosyltransferase activity	0.00877792301695221
GO:0016763	transferase activity, transferring pentosyl groups	0.0217772420971895
GO:0030686	90S preribosome	0.0217772420971895
GO:0030689	Noc complex	0.0217772420971895
GO:0030690	Noc1p-Noc2p complex	0.0217772420971895
GO:0030687	nucleolar preribosome, large subunit precursor	0.0217772420971895
GO:0006014	D-ribose metabolic process	0.0217772420971895
GO:0004747	ribokinase activity	0.0217772420971895
GO:0006868	glutamine transport	0.0348302241563201
GO:0015186	L-glutamine transmembrane transporter activity	0.0348302241563201
GO:0015802	basic amino acid transport	0.0401733084262888
GO:0030685	nucleolar preribosome	0.0401733084262888
GO:0030684	preribosome	0.0401733084262888
GO:0015174	basic amino acid transmembrane transporter activity	0.0497193097025199

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
endoderm-derived structure	1.97e-20	118
endoderm	1.97e-20	118
presumptive endoderm	1.97e-20	118
digestive system	4.22e-20	116
digestive tract	4.22e-20	116
primitive gut	4.22e-20	116
subdivision of digestive tract	5.07e-19	114
intestine	1.65e-11	31
gastrointestinal system	2.05e-11	47
gut epithelium	2.08e-11	55
unilaminar epithelium	6.88e-11	66
endo-epithelium	1.07e-10	69
organ component layer	4.31e-10	24
hemolymphoid system	4.77e-09	48
immune system	4.77e-09	48
mucosa	1.73e-08	15
foregut	6.83e-08	80
hematopoietic system	1.13e-07	45
blood island	1.13e-07	45
intestinal mucosa	1.70e-07	13
anatomical wall	1.70e-07	13
wall of intestine	1.70e-07	13
gastrointestinal system mucosa	1.70e-07	13
exocrine gland	8.69e-07	25
exocrine system	8.69e-07	25

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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