FFCP PHASE1:Hg19::chr6:116381992..116382006,-: Difference between revisions
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|ontology_enrichment_celltype=CL:0000066!1.00e-15!254;CL:0000223!6.50e-15!59;CL:0002076!1.06e-11!43;CL:0002251!1.29e-09!21 | |ontology_enrichment_celltype=CL:0000066!1.00e-15!254;CL:0000223!6.50e-15!59;CL:0002076!1.06e-11!43;CL:0002251!1.29e-09!21 | ||
|ontology_enrichment_celltype_v019=CL:0002166;1.59e-07;3!CL:0002251;7.98e-07;20!CL:0002076;7.99e-07;42 | |ontology_enrichment_celltype_v019=CL:0002166;1.59e-07;3!CL:0002251;7.98e-07;20!CL:0002076;7.99e-07;42 | ||
|ontology_enrichment_celltype_v019_2=CL:0000223,2.03e-10,58;CL:0000066,5.74e-10,253;CL:0002166,9.53e-08,3;CL:0002076,5.82e-07,42;CL:0002251,8.80e-07,20 | |||
|ontology_enrichment_development_v019=UBERON:0006595;1.33e-07;86!UBERON:0003104;6.08e-07;31 | |ontology_enrichment_development_v019=UBERON:0006595;1.33e-07;86!UBERON:0003104;6.08e-07;31 | ||
|ontology_enrichment_disease=DOID:305!2.10e-24!106;DOID:0050687!2.62e-19!143;DOID:299!2.00e-13!25;DOID:14566!1.06e-10!239;DOID:1749!1.69e-10!14;DOID:162!3.64e-10!235 | |ontology_enrichment_disease=DOID:305!2.10e-24!106;DOID:0050687!2.62e-19!143;DOID:299!2.00e-13!25;DOID:14566!1.06e-10!239;DOID:1749!1.69e-10!14;DOID:162!3.64e-10!235 | ||
|ontology_enrichment_disease_v019=DOID:1749;8.63e-13;14 | |ontology_enrichment_disease_v019=DOID:1749;8.63e-13;14 | ||
|ontology_enrichment_disease_v019_2=DOID:305,2.20e-16,106;DOID:1749,5.69e-13,14;DOID:0050687,7.42e-11,143 | |||
|ontology_enrichment_uberon=UBERON:0004119!1.61e-24!169;UBERON:0000925!1.61e-24!169;UBERON:0006595!1.61e-24!169;UBERON:0001007!1.69e-22!155;UBERON:0001555!1.69e-22!155;UBERON:0007026!1.69e-22!155;UBERON:0004921!1.94e-19!129;UBERON:0004185!1.94e-19!129;UBERON:0000077!1.99e-15!130;UBERON:0005911!2.90e-12!82;UBERON:0001041!1.33e-11!98;UBERON:0001004!7.06e-11!72;UBERON:0000161!2.90e-10!35;UBERON:0003104!3.90e-10!238;UBERON:0009142!3.90e-10!238;UBERON:0000481!1.22e-09!347;UBERON:0003929!2.24e-09!54;UBERON:0005409!2.76e-09!35;UBERON:0000466!8.17e-09!126;UBERON:0000344!1.06e-08!12;UBERON:0000166!9.20e-08!21;UBERON:0005177!1.16e-07!107;UBERON:0005156!3.20e-07!59;UBERON:0000990!3.20e-07!59;UBERON:0009569!7.71e-07!113 | |ontology_enrichment_uberon=UBERON:0004119!1.61e-24!169;UBERON:0000925!1.61e-24!169;UBERON:0006595!1.61e-24!169;UBERON:0001007!1.69e-22!155;UBERON:0001555!1.69e-22!155;UBERON:0007026!1.69e-22!155;UBERON:0004921!1.94e-19!129;UBERON:0004185!1.94e-19!129;UBERON:0000077!1.99e-15!130;UBERON:0005911!2.90e-12!82;UBERON:0001041!1.33e-11!98;UBERON:0001004!7.06e-11!72;UBERON:0000161!2.90e-10!35;UBERON:0003104!3.90e-10!238;UBERON:0009142!3.90e-10!238;UBERON:0000481!1.22e-09!347;UBERON:0003929!2.24e-09!54;UBERON:0005409!2.76e-09!35;UBERON:0000466!8.17e-09!126;UBERON:0000344!1.06e-08!12;UBERON:0000166!9.20e-08!21;UBERON:0005177!1.16e-07!107;UBERON:0005156!3.20e-07!59;UBERON:0000990!3.20e-07!59;UBERON:0009569!7.71e-07!113 | ||
|ontology_enrichment_uberon_v019=UBERON:0003343;3.99e-10;4!UBERON:0004785;3.99e-10;4!UBERON:0002423;5.32e-10;25!UBERON:0000974;5.34e-10;6!UBERON:0005409;1.08e-09;22!UBERON:0002108;2.42e-09;4!UBERON:0002294;4.57e-09;7!UBERON:0001173;4.57e-09;7!UBERON:0004921;1.11e-08;33!UBERON:0000160;2.38e-08;17!UBERON:0001007;5.66e-08;81!UBERON:0002110;7.61e-08;3!UBERON:0004175;2.14e-07;21 | |ontology_enrichment_uberon_v019=UBERON:0003343;3.99e-10;4!UBERON:0004785;3.99e-10;4!UBERON:0002423;5.32e-10;25!UBERON:0000974;5.34e-10;6!UBERON:0005409;1.08e-09;22!UBERON:0002108;2.42e-09;4!UBERON:0002294;4.57e-09;7!UBERON:0001173;4.57e-09;7!UBERON:0004921;1.11e-08;33!UBERON:0000160;2.38e-08;17!UBERON:0001007;5.66e-08;81!UBERON:0002110;7.61e-08;3!UBERON:0004175;2.14e-07;21 | ||
|ontology_enrichment_uberon_v019_2=UBERON:0001007,7.57e-18,145;UBERON:0001555,7.57e-18,145;UBERON:0007026,7.57e-18,145;UBERON:0004119,3.17e-16,160;UBERON:0000925,3.17e-16,160;UBERON:0006595,3.17e-16,160;UBERON:0004921,3.58e-15,118;UBERON:0005409,4.41e-10,25;UBERON:0009497,5.23e-10,25;UBERON:0000015,5.23e-10,25;UBERON:0002423,5.23e-10,25;UBERON:0006235,5.23e-10,25;UBERON:0004161,5.23e-10,25;UBERON:0003343,5.52e-10,4;UBERON:0004785,5.52e-10,4;UBERON:0002108,2.63e-09,4;UBERON:0005911,8.21e-09,82;UBERON:0005177,1.37e-08,101;UBERON:0000160,3.09e-08,17;UBERON:0001041,4.41e-08,87;UBERON:0002110,5.47e-08,3;UBERON:0006242,5.47e-08,3;UBERON:0003929,6.91e-08,54;UBERON:0009569,3.39e-07,112;UBERON:0002294,4.75e-07,9;UBERON:0001173,4.75e-07,9;UBERON:0004912,4.75e-07,9 | |||
|phase1_expression=0.181678379270557,0.214100523890983,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.136874425072884,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.223915474239924,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.486634870302636,0,0,0,0.327447688744282,0,0.741568885568859,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.12663051166458,0.264818361626438,0.286836620748814,0,0,0,0,0.311211035399766,0,0.163461903113459,0,0,0,0,0,0,0,0,0,0.204154171254893,0,0.206651562351531,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.386521706326594,2.72746120590835,0.860413786167011,0,0,0,0.10366105501537,0,0,0,0,0,0,0,0.354920400119532,0.168584690078102,0,0.220587945464788,0,0.237270619111097,0.404493924480493,0,0,0,0,0,0,5.07020139287323,1.96565443335525,0,0,2.09080345523293,0,0.548751427043128,0,0,0.277765335475589,0,0,0,0,0,0,0,0,0,0.858486162094873,0,0.234004265139238,0,1.87467667973554,1.51183915378974,1.41775097242386,0.0895585227028483,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.355391948742546,0,2.1100756394171,0.871533458600294,0.399891964728228,0,0,0,0,0,0,0.144781306667579,0,0.537182889719687,0,0.197030760201927,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.153461973288062,0,0,0,0,0,0,0,0,0,0,1.20859449591622,0.601519410909855,0.276242966807689,1.14814448164607,0,0,0,0.847168708148562,0,0,1.47772280450026,0,0,0.215915916102139,0,0,0,0.764628819135115,0,0,0,0,0,0,0,2.57602529119306,0,0,0,0,0,0,0,0,0,0,0,0,0.178064071293475,0.661139661443912,0.576570202095319,2.04180339991335,0.4046311234222,0,0,0,0,0,0,0,0.286249773483982,0,0.316379424718726,0,0,0,0,0,0,0,0,0.202182481573316,0,0,0,3.41198885483798,0,0,1.97967604735198,0,0.551365343546124,0,0.438450885253763,0,0,0.202910376962704,0.30982349809975,0,0,0,0,0,0,0.329294892959902,0,0,0.192444225451024,0,0,1.60044461320525,0.43050537267123,0,0.886860307073351,0.229723400206959,0,0,0,0,0,0,0,0,0,0,1.47024129588619,0.371606350251437,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.30998378285754,0.439524537815682,0,0.334330152832435,0,0,0,0,0,0,0,0,0.211125408127993,5.77819165928102,0.828851746593443,2.26739473068848,0,1.23084805461069,0,0.808815160325942,4.83357171624145,0,0.690503839458535,0,0,0,0,0,4.16684417736373,0,0,0.796554137998498,1.77977555204936,0.472775363535873,0,0,0,0,0.120596438625408,0,0.110579259931225,0,0,0,1.81250867562184,1.07730361905316,0,0.23056390438806,0,0.217294743844016,0.31900115973192,0.366390373607449,0,0,0,0,0,0,0,0,0.158936578980379,0.210998064528027,1.46909527343233,0.424059214301822,0.865554558968364,0.995261931078505,4.68825091867698,4.27721101453538,0,0,0,0,0.802577647298789,0,0.547364367646998,1.76098157038881,0,0.789168805698781,2.41981432097328,0,0.568679216656392,0,0,0,0,0,0,1.99226682220855,0,0.694238953340524,1.95984794828755,1.91530254476886,1.7472666824203,0,0.483781656445426,1.16942907337897,0.739039113478883,1.74580229679155,0,1.12990370390266,0,0,0.0633107959558787,2.93327074102205,1.84365286578528,1.28071796843612,0.39961921916426,0.864542502924636,0,0,0.864328787928898,0.124252535565433,1.88555227693436,0,0,0,0,0,0,0,1.71906176567983,0,0,2.97908551215189,0,0.998395002494955,0.429226048136571,0,0.201550417460179,0,0,1.02418136999391,0.741742725430498,1.14586024552114,7.57891607663566,0,0,0,0,0,0,0,0,0,0,2.28536551167675,0.734364233889974,0,0.717149357331379,0.383830394638891,0,0,0,0,1.72844298240254,0.326587360109409,1.19730191562487,0,0.511164065356265,0.226624183040251,2.93104467356165,0,0,0.13223260174269,1.02652102730598,4.22889013390003,0.427149650270779,0.78602152549833,1.24271716604159,0,1.58089305518355,4.38453354171225,5.10673006216145,0,0,0,0,0.628216385000937,0,0,0,0,0.110929051536852,0.0620964029413835,0,0,0,0,0,0,0,0,0,0,0.189403005275089,0.251567901752575,0,0,0,0,0,0,0,0.155262956876259,0.414706207840855,0,0,0,0,0,0,0.107410557042488,0,0,0,0,0,0,0.192619830407303,0,0,1.13352962756136,0.231522474323834,0,0,0.308801447160972,0.219284049578707,0.176689145945881,0,0,0.512483037175893,0,0,0,0,0,0,0,0.983091635014877,0.633936370075881,0,0,0.172214979660816,0,0,0,0,0,0,0,0,0,0.425149840203366,0,0.558644917973244,0,0,0,0,0,0,0,0,0,0,0,0,0,2.15924980702256,1.41563668017288,2.01771458373847,1.38630799380406,0,0,0,0.150420656698515,0,0.781514011233092,0.261906694481422,0.163771917510097,6.50566779354999,0,0,0,0,0,0,0.992422356778588,0.175871244359621,3.19406069098988,0,0,0,0.455324382702595,0.79832133146375,0,0.342976018874837,0,0,0,0.556157009460346,0.39246546425257,0,1.12108865325516,0,1.07963795609311,0.47775168788705,0.0714765441766563,0,0,0.347716544605159,0,0.414432328326074,0.17071847709395,0,0.430227358820278,0,0.0852134047591577,1.69354820076372,1.3746412112643,0.31020638566432,0,0.447421727191169,2.94450700845729,0.487671699929078,0,0.205325613712494,1.1598144313382,0.485710993059139,0.233939463462106,0,0,0,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|phase1_expression=0.181678379270557,0.214100523890983,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.136874425072884,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.223915474239924,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.486634870302636,0,0,0,0.327447688744282,0,0.741568885568859,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.12663051166458,0.264818361626438,0.286836620748814,0,0,0,0,0.311211035399766,0,0.163461903113459,0,0,0,0,0,0,0,0,0,0.204154171254893,0,0.206651562351531,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.386521706326594,2.72746120590835,0.860413786167011,0,0,0,0.10366105501537,0,0,0,0,0,0,0,0.354920400119532,0.168584690078102,0,0.220587945464788,0,0.237270619111097,0.404493924480493,0,0,0,0,0,0,5.07020139287323,1.96565443335525,0,0,2.09080345523293,0,0.548751427043128,0,0,0.277765335475589,0,0,0,0,0,0,0,0,0,0.858486162094873,0,0.234004265139238,0,1.87467667973554,1.51183915378974,1.41775097242386,0.0895585227028483,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.355391948742546,0,2.1100756394171,0.871533458600294,0.399891964728228,0,0,0,0,0,0,0.144781306667579,0,0.537182889719687,0,0.197030760201927,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.153461973288062,0,0,0,0,0,0,0,0,0,0,1.20859449591622,0.601519410909855,0.276242966807689,1.14814448164607,0,0,0,0.847168708148562,0,0,1.47772280450026,0,0,0.215915916102139,0,0,0,0.764628819135115,0,0,0,0,0,0,0,2.57602529119306,0,0,0,0,0,0,0,0,0,0,0,0,0.178064071293475,0.661139661443912,0.576570202095319,2.04180339991335,0.4046311234222,0,0,0,0,0,0,0,0.286249773483982,0,0.316379424718726,0,0,0,0,0,0,0,0,0.202182481573316,0,0,0,3.41198885483798,0,0,1.97967604735198,0,0.551365343546124,0,0.438450885253763,0,0,0.202910376962704,0.30982349809975,0,0,0,0,0,0,0.329294892959902,0,0,0.192444225451024,0,0,1.60044461320525,0.43050537267123,0,0.886860307073351,0.229723400206959,0,0,0,0,0,0,0,0,0,0,1.47024129588619,0.371606350251437,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.30998378285754,0.439524537815682,0,0.334330152832435,0,0,0,0,0,0,0,0,0.211125408127993,5.77819165928102,0.828851746593443,2.26739473068848,0,1.23084805461069,0,0.808815160325942,4.83357171624145,0,0.690503839458535,0,0,0,0,0,4.16684417736373,0,0,0.796554137998498,1.77977555204936,0.472775363535873,0,0,0,0,0.120596438625408,0,0.110579259931225,0,0,0,1.81250867562184,1.07730361905316,0,0.23056390438806,0,0.217294743844016,0.31900115973192,0.366390373607449,0,0,0,0,0,0,0,0,0.158936578980379,0.210998064528027,1.46909527343233,0.424059214301822,0.865554558968364,0.995261931078505,4.68825091867698,4.27721101453538,0,0,0,0,0.802577647298789,0,0.547364367646998,1.76098157038881,0,0.789168805698781,2.41981432097328,0,0.568679216656392,0,0,0,0,0,0,1.99226682220855,0,0.694238953340524,1.95984794828755,1.91530254476886,1.7472666824203,0,0.483781656445426,1.16942907337897,0.739039113478883,1.74580229679155,0,1.12990370390266,0,0,0.0633107959558787,2.93327074102205,1.84365286578528,1.28071796843612,0.39961921916426,0.864542502924636,0,0,0.864328787928898,0.124252535565433,1.88555227693436,0,0,0,0,0,0,0,1.71906176567983,0,0,2.97908551215189,0,0.998395002494955,0.429226048136571,0,0.201550417460179,0,0,1.02418136999391,0.741742725430498,1.14586024552114,7.57891607663566,0,0,0,0,0,0,0,0,0,0,2.28536551167675,0.734364233889974,0,0.717149357331379,0.383830394638891,0,0,0,0,1.72844298240254,0.326587360109409,1.19730191562487,0,0.511164065356265,0.226624183040251,2.93104467356165,0,0,0.13223260174269,1.02652102730598,4.22889013390003,0.427149650270779,0.78602152549833,1.24271716604159,0,1.58089305518355,4.38453354171225,5.10673006216145,0,0,0,0,0.628216385000937,0,0,0,0,0.110929051536852,0.0620964029413835,0,0,0,0,0,0,0,0,0,0,0.189403005275089,0.251567901752575,0,0,0,0,0,0,0,0.155262956876259,0.414706207840855,0,0,0,0,0,0,0.107410557042488,0,0,0,0,0,0,0.192619830407303,0,0,1.13352962756136,0.231522474323834,0,0,0.308801447160972,0.219284049578707,0.176689145945881,0,0,0.512483037175893,0,0,0,0,0,0,0,0.983091635014877,0.633936370075881,0,0,0.172214979660816,0,0,0,0,0,0,0,0,0,0.425149840203366,0,0.558644917973244,0,0,0,0,0,0,0,0,0,0,0,0,0,2.15924980702256,1.41563668017288,2.01771458373847,1.38630799380406,0,0,0,0.150420656698515,0,0.781514011233092,0.261906694481422,0.163771917510097,6.50566779354999,0,0,0,0,0,0,0.992422356778588,0.175871244359621,3.19406069098988,0,0,0,0.455324382702595,0.79832133146375,0,0.342976018874837,0,0,0,0.556157009460346,0.39246546425257,0,1.12108865325516,0,1.07963795609311,0.47775168788705,0.0714765441766563,0,0,0.347716544605159,0,0.414432328326074,0.17071847709395,0,0.430227358820278,0,0.0852134047591577,1.69354820076372,1.3746412112643,0.31020638566432,0,0.447421727191169,2.94450700845729,0.487671699929078,0,0.205325613712494,1.1598144313382,0.485710993059139,0.233939463462106,0,0,0,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| ||
|short_description=p3@FRK | |short_description=p3@FRK | ||
}} | }} |
Revision as of 17:41, 20 November 2012
Short description: | p3@FRK |
---|---|
Species: | Human (Homo sapiens) |
DPI dataset: | NA |
TSS-like-by-RIKEN-classifier(Yes/No): | NA |
DHS support(Yes/No): | NA |
Description: | CAGE_peak_3_at_FRK_5end |
Coexpression cluster: | NA |
Association with transcript: | -71bp_to_ENST00000368626, NM_002031, uc003pwi.1_5end |
EntrezGene: | FRK |
HGNC: | 3955 |
UniProt: | P42685 |
Genome view: | ZENBU |
View on UCSC genome browser
CAGE Expression
- Click each plot point to find sample in table
Ontology-based sample term enrichment analysis<b>Summary:</b>This analysis has been performed by utilizing wilcoxon rank sum test.When the number of associated cells/tissues are > n , randomly sampled n cells/tissues are used for P value calculation with rank sum test. this process are repeated several times, and the P values are averaged on the log space <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source dataset<br>data
Ontology term | p-value | n |
---|---|---|
endodermal cell | 2.03e-10 | 58 |
epithelial cell | 5.74e-10 | 253 |
epithelial cell of Malassez | 9.53e-08 | 3 |
endo-epithelial cell | 5.82e-07 | 42 |
epithelial cell of alimentary canal | 8.80e-07 | 20 |
Ontology term | p-value | n |
---|---|---|
digestive system | 7.57e-18 | 145 |
digestive tract | 7.57e-18 | 145 |
primitive gut | 7.57e-18 | 145 |
endoderm-derived structure | 3.17e-16 | 160 |
endoderm | 3.17e-16 | 160 |
presumptive endoderm | 3.17e-16 | 160 |
subdivision of digestive tract | 3.58e-15 | 118 |
gastrointestinal system | 4.41e-10 | 25 |
epithelium of foregut-midgut junction | 5.23e-10 | 25 |
anatomical boundary | 5.23e-10 | 25 |
hepatobiliary system | 5.23e-10 | 25 |
foregut-midgut junction | 5.23e-10 | 25 |
septum transversum | 5.23e-10 | 25 |
mucosa of oral region | 5.52e-10 | 4 |
respiratory system mucosa | 5.52e-10 | 4 |
small intestine | 2.63e-09 | 4 |
endo-epithelium | 8.21e-09 | 82 |
trunk region element | 1.37e-08 | 101 |
intestine | 3.09e-08 | 17 |
foregut | 4.41e-08 | 87 |
gallbladder | 5.47e-08 | 3 |
gall bladder primordium | 5.47e-08 | 3 |
gut epithelium | 6.91e-08 | 54 |
subdivision of trunk | 3.39e-07 | 112 |
biliary system | 4.75e-07 | 9 |
biliary tree | 4.75e-07 | 9 |
biliary bud | 4.75e-07 | 9 |
Ontology term | p-value | n |
---|---|---|
carcinoma | 2.20e-16 | 106 |
squamous cell carcinoma | 5.69e-13 | 14 |
cell type cancer | 7.42e-11 | 143 |
Property "Dpi dataset" (as page type) with input value "{{{DPIdataset}}}" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
Property "TSS like by RIKEN classifier" (as page type) with input value "{{{TSSclassifier}}}" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
Property "DHS support" (as page type) with input value "{{{DHSsupport}}}" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.