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MCL coexpression mm9:623: Difference between revisions

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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=}}
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25!1.83e-12!6;CL:0002436!1.83e-12!6;CL:0002427!1.83e-12!6;CL:0002428!1.83e-12!6;CL:0002429!1.83e-12!6;CL:0002433!1.83e-12!6;CL:0002431!1.83e-12!6;CL:0002432!1.83e-12!6;CL:0002320!3.02e-12!46;CL:0000134!3.02e-12!46;CL:0000219!1.15e-09!54;CL:0000034!1.88e-07!97|ontology_enrichment_disease=DOID:0060100!5.81e-07!3;DOID:4045!5.81e-07!3|ontology_enrichment_uberon=UBERON:0002370!4.12e-15!23;UBERON:0000974!4.12e-15!23;UBERON:0004807!4.12e-15!23;UBERON:0005058!4.12e-15!23;UBERON:0003351!4.12e-15!23;UBERON:0009113!4.12e-15!23;UBERON:0003295!4.12e-15!23;UBERON:0009722!4.12e-15!23;UBERON:0005562!4.12e-15!23;UBERON:0007690!4.12e-15!23;UBERON:0002193!6.48e-15!48;UBERON:0002405!6.48e-15!48;UBERON:0002390!1.08e-14!45;UBERON:0003061!1.08e-14!45;UBERON:0004177!1.32e-14!29;UBERON:0005057!1.32e-14!29;UBERON:0006562!2.53e-14!24;UBERON:0003408!2.53e-14!24;UBERON:0001557!2.53e-14!24;UBERON:0001042!2.53e-14!24;UBERON:0008814!2.53e-14!24;UBERON:0009145!2.53e-14!24;UBERON:0000077!5.07e-13!35;UBERON:0000065!8.51e-13!41;UBERON:0001004!2.26e-12!42;UBERON:0000072!2.60e-12!27;UBERON:0002384!3.02e-12!46;UBERON:0000063!1.16e-08!35;UBERON:0007811!2.53e-08!36;UBERON:0005911!2.54e-07!69;UBERON:0001041!4.20e-07!80|tfbs_overrepresentation_for_novel_motifs=0.737036,0.2332,0.686572,0.303186,0.922539,0.847245,0.396495,0.0908011,0.658686,0.336879,1.67609,0.385627,0.0909495,0.407615,0.974258,0,0.587245,0.150639,0.586013,0.33293,0.215242,0.725792,0.406794,0.155356,0.701128,1.93601,0.265362,0.334131,0.191143,0.438367,0.860721,0.683831,0.14899,0.234079,0.169391,0.406983,0.142225,0.995071,0.398832,0.347926,0.466602,0.326286,0.668798,0.508662,0.153213,0.293566,0.512146,0.34807,0.337012,0.564214,0.570705,0.457464,0.419161,0.82076,0.837732,0.414119,0.200484,0.37415,0.0716833,1.0604,0.664611,0.46618,1.14744,0.560059,1.08652,0.598412,0.970969,1.3158,0.660133,1.17005,1.21364,0.313987,0.251765,0.870406,0.240236,0.483805,1.81769,0.50152,0.648171,0.218647,0.0952669,0.60374,0.464847,0.0868537,0.758319,0.580776,0.237482,0.766772,1.28512,1.47691,1.03946,0.763136,0.696137,0.16091,0.12392,0.11194,0.299765,0.698838,0.512384,0.0434558,0.438441,0.683562,0.803823,0.571268,0.57027,0.3259,0.627019,0.344504,0.222586,0.216685,0.261228,0.805555,0.626352,0.361667,1.04639,0.152197,1.04217,0.826326,1.43693,0.43155,0.875675,0.540309,1.94166,0.500675,1.09972,0.651709,0.403884,0.689622,0.969481,0.95011,0.787341,0.296885,0.940498,0.426575,1.06766,0.440587,0.274293,0.327523,1.01927,1.84381,1.44523,0.975592,0.445463,0.693891,0.564145,0.326684,0.515065,1.80426,0.276297,0.927992,0.445509,0.209642,0.822286,0.370892,0.425729,0.901933,0.458393,0.52735,0.73227,0.752802,1.02862,0.757491,0.652135,0.25933,0.561023,0.418964,0.858861,0.384198,2.50591|tfbs_overrepresentation_jaspar=MA0003.1;0.829197,MA0004.1;0.819913,MA0006.1;0.496735,MA0007.1;0.290695,MA0009.1;1.68923,MA0014.1;1.34901,MA0017.1;0.546298,MA0019.1;0.535691,MA0024.1;0.667197,MA0025.1;0.936082,MA0027.1;2.34178,MA0028.1;0.992869,MA0029.1;0.64639,MA0030.1;0.65267,MA0031.1;0.618697,MA0038.1;0.432665,MA0040.1;0.721328,MA0041.1;0.239557,MA0042.1;0.648006,MA0043.1;0.802848,MA0046.1;0.743934,MA0048.1;0.0440103,MA0050.1;0.337476,MA0051.1;0.440863,MA0052.1;0.729105,MA0055.1;0.10681,MA0056.1;0,MA0057.1;0.983678,MA0058.1;1.18867,MA0059.1;1.22696,MA0060.1;0.713464,MA0061.1;0.40468,MA0063.1;0,MA0066.1;0.422624,MA0067.1;1.04514,MA0068.1;0.647449,MA0069.1;0.729433,MA0070.1;0.720077,MA0071.1;0.336739,MA0072.1;0.711905,MA0073.1;1.69472,MA0074.1;0.390075,MA0076.1;1.10234,MA0077.1;0.691048,MA0078.1;0.471303,MA0081.1;0.702944,MA0083.1;0.802078,MA0084.1;1.3693,MA0087.1;0.760279,MA0088.1;0.24301,MA0089.1;0,MA0090.1;0.27428,MA0091.1;1.52754,MA0092.1;0.274547,MA0093.1;1.01857,MA0095.1;0,MA0098.1;0,MA0100.1;0.379666,MA0101.1;0.240622,MA0103.1;0.566591,MA0105.1;0.226879,MA0106.1;0.478503,MA0107.1;0.555009,MA0108.2;0.557195,MA0109.1;0,MA0111.1;0.286331,MA0113.1;0.452439,MA0114.1;0.797973,MA0115.1;0.805567,MA0116.1;0.165534,MA0117.1;0.774259,MA0119.1;0.241106,MA0122.1;0.793507,MA0124.1;0.992825,MA0125.1;0.920215,MA0130.1;0,MA0131.1;0.531427,MA0132.1;0,MA0133.1;0,MA0135.1;0.838263,MA0136.1;1.05128,MA0139.1;0.61859,MA0140.1;0.379562,MA0141.1;0.603844,MA0142.1;0.604892,MA0143.1;0.467531,MA0144.1;0.807435,MA0145.1;0.494714,MA0146.1;1.9229,MA0147.1;0.845188,MA0148.1;0.317692,MA0149.1;0.245177,MA0062.2;1.31267,MA0035.2;0.383789,MA0039.2;1.12665,MA0138.2;0.523978,MA0002.2;0.627335,MA0137.2;0.207733,MA0104.2;1.1126,MA0047.2;0.431964,MA0112.2;1.15536,MA0065.2;0.79588,MA0150.1;0.290598,MA0151.1;0,MA0152.1;0.432062,MA0153.1;0.854464,MA0154.1;1.03999,MA0155.1;1.71283,MA0156.1;1.72768,MA0157.1;0.574484,MA0158.1;0,MA0159.1;0.446593,MA0160.1;0.85749,MA0161.1;0,MA0162.1;2.12712,MA0163.1;0.962545,MA0164.1;0.408402,MA0080.2;2.37215,MA0018.2;0.417217,MA0099.2;1.28797,MA0079.2;4.18363,MA0102.2;1.42135,MA0258.1;1.23793,MA0259.1;0.130633,MA0442.1;0}}

Latest revision as of 15:37, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr16:55973950..55973977,+p4@Rpl24
p4@Zbtb11
Mm9::chr19:53497833..53497852,-p@chr19:53497833..53497852
-
Mm9::chr2:126326367..126326411,-p6@Atp8b4
Mm9::chr4:48056512..48056524,+p@chr4:48056512..48056524
+
Mm9::chr4:8764875..8764901,+p@chr4:8764875..8764901
+
Mm9::chr4:8764972..8764983,+p@chr4:8764972..8764983
+
Mm9::chr5:32435323..32435338,-p3@Gm10463
Mm9::chr7:31941380..31941419,-p@chr7:31941380..31941419
-
Mm9::chr7:88138900..88138902,+p@chr7:88138900..88138902
+
Mm9::chr8:83538765..83538841,-p1@Usp38
Mm9::chr8:87185489..87185504,-p@chr8:87185489..87185504
-
Mm9::chr9:45753710..45753714,-p@chr9:45753710..45753714
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


no results for this coexpression

Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen
lymphoid lineage restricted progenitor cell2.83e-2212
T cell1.65e-2011
pro-T cell1.65e-2011
lymphocyte2.55e-2013
common lymphoid progenitor2.55e-2013
mature alpha-beta T cell4.73e-189
alpha-beta T cell4.73e-189
immature T cell4.73e-189
mature T cell4.73e-189
immature alpha-beta T cell4.73e-189
hematopoietic cell9.11e-1832
hematopoietic oligopotent progenitor cell9.11e-1832
hematopoietic stem cell9.11e-1832
angioblastic mesenchymal cell9.11e-1832
hematopoietic multipotent progenitor cell9.11e-1832
CD4-positive, alpha-beta T cell4.50e-168
nucleate cell6.29e-1616
leukocyte8.25e-1517
nongranular leukocyte8.25e-1517
hematopoietic lineage restricted progenitor cell1.52e-1425
thymocyte1.83e-126
double negative thymocyte1.83e-126
naive T cell1.83e-126
double-positive, alpha-beta thymocyte1.83e-126
CD4-positive, alpha-beta thymocyte1.83e-126
naive thymus-derived CD4-positive, alpha-beta T cell1.83e-126
DN4 thymocyte1.83e-126
DN1 thymic pro-T cell1.83e-126
DN2 thymocyte1.83e-126
DN3 thymocyte1.83e-126
immature single positive thymocyte1.83e-126
early T lineage precursor1.83e-126
mature CD4 single-positive thymocyte1.83e-126
resting double-positive thymocyte1.83e-126
double-positive blast1.83e-126
CD69-positive double-positive thymocyte1.83e-126
CD69-positive, CD4-positive single-positive thymocyte1.83e-126
CD4-positive, CD8-intermediate double-positive thymocyte1.83e-126
CD24-positive, CD4 single-positive thymocyte1.83e-126
connective tissue cell3.02e-1246
mesenchymal cell3.02e-1246
motile cell1.15e-0954
stem cell1.88e-0797

Uber Anatomy
Ontology termp-valuen
thymus4.12e-1523
neck4.12e-1523
respiratory system epithelium4.12e-1523
hemolymphoid system gland4.12e-1523
pharyngeal epithelium4.12e-1523
thymic region4.12e-1523
pharyngeal gland4.12e-1523
entire pharyngeal arch endoderm4.12e-1523
thymus primordium4.12e-1523
early pharyngeal endoderm4.12e-1523
hemolymphoid system6.48e-1548
immune system6.48e-1548
hematopoietic system1.08e-1445
blood island1.08e-1445
hemopoietic organ1.32e-1429
immune organ1.32e-1429
pharynx2.53e-1424
gland of gut2.53e-1424
upper respiratory tract2.53e-1424
chordate pharynx2.53e-1424
pharyngeal arch system2.53e-1424
pharyngeal region of foregut2.53e-1424
mixed endoderm/mesoderm-derived structure5.07e-1335
respiratory tract8.51e-1341
respiratory system2.26e-1242
segment of respiratory tract2.60e-1227
connective tissue3.02e-1246
organ segment1.16e-0835
craniocervical region2.53e-0836
endo-epithelium2.54e-0769
foregut4.20e-0780

Disease
Ontology termp-valuen
musculoskeletal system cancer5.81e-073
muscle cancer5.81e-073


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.829197
MA0004.10.819913
MA0006.10.496735
MA0007.10.290695
MA0009.11.68923
MA0014.11.34901
MA0017.10.546298
MA0019.10.535691
MA0024.10.667197
MA0025.10.936082
MA0027.12.34178
MA0028.10.992869
MA0029.10.64639
MA0030.10.65267
MA0031.10.618697
MA0038.10.432665
MA0040.10.721328
MA0041.10.239557
MA0042.10.648006
MA0043.10.802848
MA0046.10.743934
MA0048.10.0440103
MA0050.10.337476
MA0051.10.440863
MA0052.10.729105
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MA0108.20.557195
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MA0130.10
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MA0135.10.838263
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MA0102.21.42135
MA0258.11.23793
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MA0442.10