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MCL coexpression mm9:175: Difference between revisions

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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0019752;carboxylic acid metabolic process;0.0287311660886267;56248,74156,26458,14630,107747,11430!GO:0006082;organic acid metabolic process;0.0287311660886267;56248,74156,26458,14630,107747,11430!GO:0005739;mitochondrion;0.0287311660886267;13804,11430,56248,17713,93757,26926,26458,18408!GO:0044444;cytoplasmic part;0.0287311660886267;74156,69865,13804,14073,99586,11430,56248,17713,71767,93757,26458,26926,18408,14630!GO:0016491;oxidoreductase activity;0.0287311660886267;19683,99586,26926,14630,107747,11529,11430!GO:0042579;microbody;0.0287311660886267;71767,26458,11430!GO:0005777;peroxisome;0.0287311660886267;71767,26458,11430!GO:0016645;oxidoreductase activity, acting on the CH-NH group of donors;0.0287311660886267;26926,107747!GO:0032787;monocarboxylic acid metabolic process;0.0287311660886267;74156,26458,107747,11430!GO:0006725;aromatic compound metabolic process;0.0303248781022298;99586,66082,107747!GO:0004040;amidase activity;0.0303248781022298;14073!GO:0009397;folic acid and derivative catabolic process;0.0303248781022298;107747!GO:0046899;nucleoside triphosphate adenylate kinase activity;0.0303248781022298;56248!GO:0046113;nucleobase catabolic process;0.0303248781022298;99586!GO:0042720;mitochondrial inner membrane peptidase complex;0.0303248781022298;93757!GO:0035229;positive regulation of glutamate-cysteine ligase activity;0.0303248781022298;14630!GO:0004244;mitochondrial inner membrane peptidase activity;0.0303248781022298;93757!GO:0009258;10-formyltetrahydrofolate catabolic process;0.0303248781022298;107747!GO:0035226;glutamate-cysteine ligase catalytic subunit binding;0.0303248781022298;14630!GO:0017113;dihydropyrimidine dehydrogenase (NADP+) activity;0.0303248781022298;99586!GO:0006627;mitochondrial protein processing;0.0303248781022298;93757!GO:0004884;ecdysteroid hormone receptor activity;0.0303248781022298;22259!GO:0006208;pyrimidine base catabolic process;0.0303248781022298;99586!GO:0035227;regulation of glutamate-cysteine ligase activity;0.0303248781022298;14630!GO:0051351;positive regulation of ligase activity;0.0303248781022298;14630!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0329320261885065;99586,11430!GO:0016787;hydrolase activity;0.0329320261885065;76051,227292,74156,13804,14073,218294,69834,71767,93757,66082!GO:0006732;coenzyme metabolic process;0.0329320261885065;74156,14630,107747!GO:0006631;fatty acid metabolic process;0.0329320261885065;74156,26458,11430!GO:0048037;cofactor binding;0.0329320261885065;26926,107747,11430!GO:0051882;mitochondrial depolarization;0.0329320261885065;14630!GO:0004765;shikimate kinase activity;0.0329320261885065;56248!GO:0004357;glutamate-cysteine ligase activity;0.0329320261885065;14630!GO:0000774;adenyl-nucleotide exchange factor activity;0.0329320261885065;17713!GO:0003986;acetyl-CoA hydrolase activity;0.0329320261885065;74156!GO:0051340;regulation of ligase activity;0.0329320261885065;14630!GO:0016649;oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor;0.0329320261885065;26926!GO:0004301;epoxide hydrolase activity;0.0329320261885065;66082!GO:0051900;regulation of mitochondrial depolarization;0.0329320261885065;14630!GO:0017109;glutamate-cysteine ligase complex;0.0329320261885065;14630!GO:0004174;electron-transferring-flavoprotein dehydrogenase activity;0.0329320261885065;26926!GO:0016554;cytidine to uridine editing;0.0329320261885065;69865!GO:0004756;selenide, water dikinase activity;0.0329320261885065;20768!GO:0009256;10-formyltetrahydrofolate metabolic process;0.0329320261885065;107747!GO:0016155;formyltetrahydrofolate dehydrogenase activity;0.0329320261885065;107747!GO:0016781;phosphotransferase activity, paired acceptors;0.0329320261885065;20768!GO:0005737;cytoplasm;0.0352784346436778;13804,18024,11430,17713,71767,26458,26926,18408,107747,69865,74156,99586,14073,56248,67815,93757,14630,11529!GO:0031975;envelope;0.0405402885649097;93757,117591,26926,18408!GO:0031967;organelle envelope;0.0405402885649097;93757,117591,26926,18408!GO:0051186;cofactor metabolic process;0.0405402885649097;74156,14630,107747!GO:0050660;FAD binding;0.0405402885649097;26926,11430!GO:0004240;mitochondrial processing peptidase activity;0.0405402885649097;93757!GO:0051881;regulation of mitochondrial membrane potential;0.0405402885649097;14630!GO:0016803;ether hydrolase activity;0.0405402885649097;66082!GO:0016553;base conversion or substitution editing;0.0405402885649097;69865!GO:0004463;leukotriene-A4 hydrolase activity;0.0405402885649097;66082!GO:0046983;protein dimerization activity;0.0419437696077455;17713,18024,14630!GO:0046483;heterocycle metabolic process;0.0470481888015543;99586,107747!GO:0007005;mitochondrion organization and biogenesis;0.0476185188395778;93757,26926!GO:0003997;acyl-CoA oxidase activity;0.0495782494533212;11430!GO:0004558;alpha-glucosidase activity;0.0495782494533212;76051!}}
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122843244622472,0.0877557052419966,0.120876255993453,0.0978461107777356,0.119503963466379,0.139013627015232,0.138165606837579,0.0935541597761707,0.0914889658526459,0.114480663127171,0.0978413060200696,0.141706336142815,0.109163845046426,0.0907308677719409,0.128033729919821,0.119197609719738,0.092873634605593,0.0676310163996545,0.10799917315244,0.0982434449953899,0.135298729868652,0.101427320830301,0.104353329269123,0.133318087294839,0.0916014488467587,0.0944295193704905,0.0821050099562557,0.0866745961153834,0.0766064454112358,0,0.138740837237052,0.164607253353292,0.0206219462404444,0.0630283521584416,0.0169362290408348|gostat_on_MCL_coexpression=GO:0019752;carboxylic acid metabolic process;0.0287311660886267;56248,74156,26458,14630,107747,11430!GO:0006082;organic acid metabolic process;0.0287311660886267;56248,74156,26458,14630,107747,11430!GO:0005739;mitochondrion;0.0287311660886267;13804,11430,56248,17713,93757,26926,26458,18408!GO:0044444;cytoplasmic part;0.0287311660886267;74156,69865,13804,14073,99586,11430,56248,17713,71767,93757,26458,26926,18408,14630!GO:0016491;oxidoreductase activity;0.0287311660886267;19683,99586,26926,14630,107747,11529,11430!GO:0042579;microbody;0.0287311660886267;71767,26458,11430!GO:0005777;peroxisome;0.0287311660886267;71767,26458,11430!GO:0016645;oxidoreductase activity, acting on the CH-NH group of donors;0.0287311660886267;26926,107747!GO:0032787;monocarboxylic acid metabolic process;0.0287311660886267;74156,26458,107747,11430!GO:0006725;aromatic compound metabolic process;0.0303248781022298;99586,66082,107747!GO:0004040;amidase activity;0.0303248781022298;14073!GO:0009397;folic acid and derivative catabolic process;0.0303248781022298;107747!GO:0046899;nucleoside triphosphate adenylate kinase activity;0.0303248781022298;56248!GO:0046113;nucleobase catabolic process;0.0303248781022298;99586!GO:0042720;mitochondrial inner membrane peptidase complex;0.0303248781022298;93757!GO:0035229;positive regulation of glutamate-cysteine ligase activity;0.0303248781022298;14630!GO:0004244;mitochondrial inner membrane peptidase activity;0.0303248781022298;93757!GO:0009258;10-formyltetrahydrofolate catabolic process;0.0303248781022298;107747!GO:0035226;glutamate-cysteine ligase catalytic subunit binding;0.0303248781022298;14630!GO:0017113;dihydropyrimidine dehydrogenase (NADP+) activity;0.0303248781022298;99586!GO:0006627;mitochondrial protein processing;0.0303248781022298;93757!GO:0004884;ecdysteroid hormone receptor activity;0.0303248781022298;22259!GO:0006208;pyrimidine base catabolic process;0.0303248781022298;99586!GO:0035227;regulation of glutamate-cysteine ligase activity;0.0303248781022298;14630!GO:0051351;positive regulation of ligase activity;0.0303248781022298;14630!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0329320261885065;99586,11430!GO:0016787;hydrolase activity;0.0329320261885065;76051,227292,74156,13804,14073,218294,69834,71767,93757,66082!GO:0006732;coenzyme metabolic process;0.0329320261885065;74156,14630,107747!GO:0006631;fatty acid metabolic process;0.0329320261885065;74156,26458,11430!GO:0048037;cofactor binding;0.0329320261885065;26926,107747,11430!GO:0051882;mitochondrial depolarization;0.0329320261885065;14630!GO:0004765;shikimate kinase activity;0.0329320261885065;56248!GO:0004357;glutamate-cysteine ligase activity;0.0329320261885065;14630!GO:0000774;adenyl-nucleotide exchange factor activity;0.0329320261885065;17713!GO:0003986;acetyl-CoA hydrolase activity;0.0329320261885065;74156!GO:0051340;regulation of ligase activity;0.0329320261885065;14630!GO:0016649;oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor;0.0329320261885065;26926!GO:0004301;epoxide hydrolase activity;0.0329320261885065;66082!GO:0051900;regulation of mitochondrial depolarization;0.0329320261885065;14630!GO:0017109;glutamate-cysteine ligase complex;0.0329320261885065;14630!GO:0004174;electron-transferring-flavoprotein dehydrogenase activity;0.0329320261885065;26926!GO:0016554;cytidine to uridine editing;0.0329320261885065;69865!GO:0004756;selenide, water dikinase activity;0.0329320261885065;20768!GO:0009256;10-formyltetrahydrofolate metabolic process;0.0329320261885065;107747!GO:0016155;formyltetrahydrofolate dehydrogenase activity;0.0329320261885065;107747!GO:0016781;phosphotransferase activity, paired acceptors;0.0329320261885065;20768!GO:0005737;cytoplasm;0.0352784346436778;13804,18024,11430,17713,71767,26458,26926,18408,107747,69865,74156,99586,14073,56248,67815,93757,14630,11529!GO:0031975;envelope;0.0405402885649097;93757,117591,26926,18408!GO:0031967;organelle envelope;0.0405402885649097;93757,117591,26926,18408!GO:0051186;cofactor metabolic process;0.0405402885649097;74156,14630,107747!GO:0050660;FAD binding;0.0405402885649097;26926,11430!GO:0004240;mitochondrial processing peptidase activity;0.0405402885649097;93757!GO:0051881;regulation of mitochondrial membrane potential;0.0405402885649097;14630!GO:0016803;ether hydrolase activity;0.0405402885649097;66082!GO:0016553;base conversion or substitution editing;0.0405402885649097;69865!GO:0004463;leukotriene-A4 hydrolase activity;0.0405402885649097;66082!GO:0046983;protein dimerization activity;0.0419437696077455;17713,18024,14630!GO:0046483;heterocycle metabolic process;0.0470481888015543;99586,107747!GO:0007005;mitochondrion organization and biogenesis;0.0476185188395778;93757,26926!GO:0003997;acyl-CoA oxidase activity;0.0495782494533212;11430!GO:0004558;alpha-glucosidase activity;0.0495782494533212;76051!|ontology_enrichment_celltype=CL:0002563!2.08e-07!9;CL:0002251!2.08e-07!9;CL:0000066!7.06e-07!25|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0000160!2.97e-18!31;UBERON:0009854!4.14e-15!23;UBERON:0009856!4.14e-15!23;UBERON:0002107!9.47e-15!22;UBERON:0007499!9.47e-15!22;UBERON:0006925!9.47e-15!22;UBERON:0009497!9.47e-15!22;UBERON:0000015!9.47e-15!22;UBERON:0002423!9.47e-15!22;UBERON:0006235!9.47e-15!22;UBERON:0008835!9.47e-15!22;UBERON:0003894!9.47e-15!22;UBERON:0004161!9.47e-15!22;UBERON:0008836!9.47e-15!22;UBERON:0005409!5.15e-14!47;UBERON:0002365!2.73e-12!25;UBERON:0002330!2.73e-12!25;UBERON:0000344!1.66e-11!15;UBERON:0004119!3.95e-11!118;UBERON:0000925!3.95e-11!118;UBERON:0006595!3.95e-11!118;UBERON:0001007!1.07e-10!116;UBERON:0001555!1.07e-10!116;UBERON:0007026!1.07e-10!116;UBERON:0001242!3.27e-10!13;UBERON:0000060!3.27e-10!13;UBERON:0001262!3.27e-10!13;UBERON:0004786!3.27e-10!13;UBERON:0005172!5.16e-10!49;UBERON:0005173!5.16e-10!49;UBERON:0002417!5.16e-10!49;UBERON:0000916!5.16e-10!49;UBERON:0004921!8.87e-10!114;UBERON:0004923!5.91e-08!24;UBERON:0003350!2.08e-07!9;UBERON:0004808!2.08e-07!9;UBERON:0001277!2.08e-07!9;UBERON:0003929!5.30e-07!55|tfbs_overrepresentation_for_novel_motifs=0.682737,0.687685,0.372495,0.168224,0.139605,0.185841,0.134211,0.630422,0.692005,2.31605,0.248832,0.296559,0.631945,0.335391,0.288969,0,0.347413,0.227795,0.268322,0.383774,0.153587,1.19198,0.33391,0.243,0.614286,0.168278,0.48995,0.671786,1.06747,1.04838,1.29727,0.15952,0.3571,0.523394,0.290244,0.139272,0.20158,1.23278,0.156551,0.185708,0.0643098,0.643421,0.263239,0.0342611,2.00872,0.155249,0.921321,0.234497,0.222096,1.0861,0.325958,0.429494,1.18231,0.247864,0.259778,0.977121,0.40434,0.114969,0.770477,0.343817,0.453716,0.202648,1.24672,0.312407,0.65461,0.362166,0.359348,0.65247,0.447315,0.523767,1.38429,0.231028,2.25292,0.283239,1.36941,0.477508,0.6867,0.51885,0.43036,0.294069,0.234654,0.369277,0.201227,0.195519,0.20577,2.47572,0.172694,0.3842,0.550899,0.800315,0.414101,1.13331,0.166838,0.149032,2.96461,0.318607,0.0682808,0.971958,0.541682,0.188477,0.000664953,0.934443,0.23617,0.0992206,0.668041,0.389141,0.400897,0.709776,2.07998,0.468216,0.422191,0.668082,0.479835,0.773772,0.41976,0.130664,1.43226,0.342086,1.71303,0.0493429,0.287084,0.287827,0.169929,0.0682066,0.463931,0.857332,0.32868,0.489976,0.358183,0.61506,0.224984,0.159674,0.335709,0.162245,0.437241,0.113679,0.269134,0.0175066,0.397743,1.15036,0.770879,0.362976,0.181037,0.165493,0.317584,0.20178,0.54736,1.11202,0.273492,1.06137,0.123548,2.06423,0.248928,0.339845,0.161424,0.826428,0.194405,0.321331,0.119612,0.463614,0.4053,0.205231,0.435956,0.112917,1.07859,0.0396464,0.67888,0.294096,2.00017|tfbs_overrepresentation_jaspar=MA0003.1;5.40056,MA0004.1;0.563304,MA0006.1;0.630914,MA0007.1;1.11209,MA0009.1;0.519036,MA0014.1;3.01742,MA0017.1;7.22336,MA0019.1;0.591638,MA0024.1;0.457425,MA0025.1;0.332323,MA0027.1;1.63967,MA0028.1;1.21059,MA0029.1;0.138094,MA0030.1;0.141597,MA0031.1;0.389494,MA0038.1;0.38168,MA0040.1;0.182227,MA0041.1;0.0307631,MA0042.1;0.0265008,MA0043.1;0.663757,MA0046.1;1.70643,MA0048.1;1.01969,MA0050.1;0.0864838,MA0051.1;0.176378,MA0052.1;1.04725,MA0055.1;0.20742,MA0056.1;0,MA0057.1;0.70933,MA0058.1;0.494826,MA0059.1;0.536299,MA0060.1;1.59503,MA0061.1;1.036,MA0063.1;0,MA0066.1;0.649826,MA0067.1;0.418736,MA0068.1;0.0638055,MA0069.1;0.549379,MA0070.1;0.18145,MA0071.1;0.681287,MA0072.1;0.52298,MA0073.1;0.00224656,MA0074.1;0.128541,MA0076.1;0.12985,MA0077.1;0.163796,MA0078.1;0.208148,MA0081.1;0.223237,MA0083.1;0.662528,MA0084.1;0.70101,MA0087.1;1.12603,MA0088.1;0.3515,MA0089.1;0,MA0090.1;0.269106,MA0091.1;0.603202,MA0092.1;0.130972,MA0093.1;0.721261,MA0095.1;0,MA0098.1;0,MA0100.1;0.286338,MA0101.1;0.567265,MA0103.1;0.57731,MA0105.1;0.833589,MA0106.1;0.215981,MA0107.1;0.363138,MA0108.2;0.638844,MA0109.1;0,MA0111.1;0.145795,MA0113.1;0.419654,MA0114.1;8.79238,MA0115.1;2.70381,MA0116.1;0.86391,MA0117.1;0.618524,MA0119.1;0.827692,MA0122.1;0.229146,MA0124.1;0.376587,MA0125.1;0.857327,MA0130.1;0,MA0131.1;0.582401,MA0132.1;0,MA0133.1;0,MA0135.1;0.260154,MA0136.1;0.036462,MA0139.1;1.01259,MA0140.1;0.528817,MA0141.1;1.93839,MA0142.1;0.370822,MA0143.1;0.449434,MA0144.1;0.164354,MA0145.1;1.62297,MA0146.1;1.86089,MA0147.1;0.655028,MA0148.1;0.369033,MA0149.1;0.0972631,MA0062.2;0.0312769,MA0035.2;0.540369,MA0039.2;2.03274,MA0138.2;0.268074,MA0002.2;0.624244,MA0137.2;0.263861,MA0104.2;0.718214,MA0047.2;0.0436413,MA0112.2;0.675866,MA0065.2;5.85929,MA0150.1;0.305334,MA0151.1;0,MA0152.1;0.167612,MA0153.1;2.93372,MA0154.1;0.992452,MA0155.1;1.43989,MA0156.1;0.0553208,MA0157.1;0.330817,MA0158.1;0,MA0159.1;0.211707,MA0160.1;1.6988,MA0161.1;0,MA0162.1;0.857656,MA0163.1;1.29806,MA0164.1;0.609076,MA0080.2;0.0142719,MA0018.2;0.634249,MA0099.2;0.0753229,MA0079.2;1.17563,MA0102.2;0.74879,MA0258.1;1.16782,MA0259.1;1.05375,MA0442.1;0}}

Latest revision as of 14:49, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:120947386..120947401,+p@chr10:120947386..120947401
+
Mm9::chr10:127238201..127238245,+p1@Rdh16
p1@Rdh18-ps
Mm9::chr10:61158251..61158324,+p1@Tysnd1
Mm9::chr10:62501849..62501865,+p@chr10:62501849..62501865
+
Mm9::chr10:79792872..79792956,+p1@Reep6
Mm9::chr11:116060015..116060150,-p1@Acox1
Mm9::chr11:120438213..120438230,+p@chr11:120438213..120438230
+
Mm9::chr11:23565410..23565438,+p6@Pus10
Mm9::chr11:4018781..4018793,-p2@Sec14l2
Mm9::chr11:49953228..49953246,-p@chr11:49953228..49953246
-
Mm9::chr11:72288510..72288534,-p2@Spns2
Mm9::chr11:73012947..73013002,+p1@Shpk
Mm9::chr12:41750683..41750721,+p1@Immp2l
Mm9::chr12:60231981..60232016,+p5@Ctage5
Mm9::chr13:64349931..64349956,-p2@Cdc14b
Mm9::chr13:91881089..91881094,+p2@Acot12
Mm9::chr14:8835463..8835493,+p2@Abhd6
Mm9::chr15:78857421..78857435,+p@chr15:78857421..78857435
+
Mm9::chr15:89207534..89207545,-p2@Tymp
Mm9::chr15:98929882..98929913,+p2@Dnajc22
Mm9::chr17:27957479..27957517,-p1@D17Wsu92e
Mm9::chr17:36046622..36046645,-p3@Atat1
Mm9::chr18:12801984..12802009,+p4@Ttc39c
Mm9::chr19:29122337..29122467,-p1@Ak3
Mm9::chr19:31943295..31943310,+p1@A1cf
Mm9::chr19:37282508..37282557,-p@chr19:37282508..37282557
-
Mm9::chr19:43857107..43857115,+p@chr19:43857107..43857115
+
Mm9::chr1:193543043..193543108,+p@chr1:193543043..193543108
+
Mm9::chr1:74438446..74438459,+p10@Ctdsp1
Mm9::chr2:120230523..120230567,+p2@Ganc
Mm9::chr2:126378572..126378629,+p2@Slc27a2
Mm9::chr2:131059779..131059872,+p1@Mavs
Mm9::chr2:30027022..30027040,+p1@Endog
Mm9::chr2:75543161..75543173,-p5@Nfe2l2
Mm9::chr2:91035197..91035237,-p1@Nr1h3
Mm9::chr2:91035254..91035271,-p3@Nr1h3
Mm9::chr3:118265063..118265074,+p2@Dpyd
Mm9::chr3:118265080..118265106,+p1@Dpyd
Mm9::chr3:121948694..121948747,+p2@Gclm
Mm9::chr3:138078448..138078474,+p1@Adh4
Mm9::chr3:85775143..85775158,+p2@uc008pqy.1
Mm9::chr4:115690261..115690369,-p1@Faah
Mm9::chr5:135582751..135582788,+p1@Mlxipl
Mm9::chr5:135604529..135604540,+p@chr5:135604529..135604540
+
Mm9::chr5:36807807..36807845,+p1@Grpel1
Mm9::chr5:38883162..38883174,-p2@Slc2a9
Mm9::chr5:38883187..38883200,-p3@Slc2a9
Mm9::chr5:53060697..53060716,-p@chr5:53060697..53060716
-
Mm9::chr6:71443844..71443912,+p1@Rnf103
Mm9::chr6:87761646..87761661,-p4@Rab43
Mm9::chr6:90500747..90500758,+p2@Aldh1l1
p2@LOC100047937
Mm9::chr7:134066401..134066440,-p3@Tmem219
Mm9::chr7:134417561..134417580,-p1@Sephs2
Mm9::chr7:52830517..52830538,-p1@ENSMUST00000130094
p1@ENSMUST00000132138
p1@ENSMUST00000145208
p1@ENSMUST00000148383
Mm9::chr7:53152839..53152904,+p2@Tmem143
Mm9::chr7:91838304..91838331,-p3@Zfand6
Mm9::chr8:126278232..126278260,+p@chr8:126278232..126278260
+
Mm9::chr8:23508732..23508748,-p@chr8:23508732..23508748
-
Mm9::chr8:23508955..23508969,-p1@Slc25a15
Mm9::chrX:39413081..39413103,+p@chrX:39413081..39413103
+
Mm9::chrX:45866621..45866636,-p3@Aifm1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0019752carboxylic acid metabolic process0.0287311660886267
GO:0006082organic acid metabolic process0.0287311660886267
GO:0005739mitochondrion0.0287311660886267
GO:0044444cytoplasmic part0.0287311660886267
GO:0016491oxidoreductase activity0.0287311660886267
GO:0042579microbody0.0287311660886267
GO:0005777peroxisome0.0287311660886267
GO:0016645oxidoreductase activity, acting on the CH-NH group of donors0.0287311660886267
GO:0032787monocarboxylic acid metabolic process0.0287311660886267
GO:0006725aromatic compound metabolic process0.0303248781022298
GO:0004040amidase activity0.0303248781022298
GO:0009397folic acid and derivative catabolic process0.0303248781022298
GO:0046899nucleoside triphosphate adenylate kinase activity0.0303248781022298
GO:0046113nucleobase catabolic process0.0303248781022298
GO:0042720mitochondrial inner membrane peptidase complex0.0303248781022298
GO:0035229positive regulation of glutamate-cysteine ligase activity0.0303248781022298
GO:0004244mitochondrial inner membrane peptidase activity0.0303248781022298
GO:000925810-formyltetrahydrofolate catabolic process0.0303248781022298
GO:0035226glutamate-cysteine ligase catalytic subunit binding0.0303248781022298
GO:0017113dihydropyrimidine dehydrogenase (NADP+) activity0.0303248781022298
GO:0006627mitochondrial protein processing0.0303248781022298
GO:0004884ecdysteroid hormone receptor activity0.0303248781022298
GO:0006208pyrimidine base catabolic process0.0303248781022298
GO:0035227regulation of glutamate-cysteine ligase activity0.0303248781022298
GO:0051351positive regulation of ligase activity0.0303248781022298
GO:0016627oxidoreductase activity, acting on the CH-CH group of donors0.0329320261885065
GO:0016787hydrolase activity0.0329320261885065
GO:0006732coenzyme metabolic process0.0329320261885065
GO:0006631fatty acid metabolic process0.0329320261885065
GO:0048037cofactor binding0.0329320261885065
GO:0051882mitochondrial depolarization0.0329320261885065
GO:0004765shikimate kinase activity0.0329320261885065
GO:0004357glutamate-cysteine ligase activity0.0329320261885065
GO:0000774adenyl-nucleotide exchange factor activity0.0329320261885065
GO:0003986acetyl-CoA hydrolase activity0.0329320261885065
GO:0051340regulation of ligase activity0.0329320261885065
GO:0016649oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor0.0329320261885065
GO:0004301epoxide hydrolase activity0.0329320261885065
GO:0051900regulation of mitochondrial depolarization0.0329320261885065
GO:0017109glutamate-cysteine ligase complex0.0329320261885065
GO:0004174electron-transferring-flavoprotein dehydrogenase activity0.0329320261885065
GO:0016554cytidine to uridine editing0.0329320261885065
GO:0004756selenide, water dikinase activity0.0329320261885065
GO:000925610-formyltetrahydrofolate metabolic process0.0329320261885065
GO:0016155formyltetrahydrofolate dehydrogenase activity0.0329320261885065
GO:0016781phosphotransferase activity, paired acceptors0.0329320261885065
GO:0005737cytoplasm0.0352784346436778
GO:0031975envelope0.0405402885649097
GO:0031967organelle envelope0.0405402885649097
GO:0051186cofactor metabolic process0.0405402885649097
GO:0050660FAD binding0.0405402885649097
GO:0004240mitochondrial processing peptidase activity0.0405402885649097
GO:0051881regulation of mitochondrial membrane potential0.0405402885649097
GO:0016803ether hydrolase activity0.0405402885649097
GO:0016553base conversion or substitution editing0.0405402885649097
GO:0004463leukotriene-A4 hydrolase activity0.0405402885649097
GO:0046983protein dimerization activity0.0419437696077455
GO:0046483heterocycle metabolic process0.0470481888015543
GO:0007005mitochondrion organization and biogenesis0.0476185188395778
GO:0003997acyl-CoA oxidase activity0.0495782494533212
GO:0004558alpha-glucosidase activity0.0495782494533212



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
intestinal epithelial cell2.08e-079
epithelial cell of alimentary canal2.08e-079
epithelial cell7.06e-0725

Uber Anatomy
Ontology termp-valuen
intestine2.97e-1831
digestive tract diverticulum4.14e-1523
sac4.14e-1523
liver9.47e-1522
epithelial sac9.47e-1522
digestive gland9.47e-1522
epithelium of foregut-midgut junction9.47e-1522
anatomical boundary9.47e-1522
hepatobiliary system9.47e-1522
foregut-midgut junction9.47e-1522
hepatic diverticulum9.47e-1522
liver primordium9.47e-1522
septum transversum9.47e-1522
liver bud9.47e-1522
gastrointestinal system5.15e-1447
exocrine gland2.73e-1225
exocrine system2.73e-1225
mucosa1.66e-1115
endoderm-derived structure3.95e-11118
endoderm3.95e-11118
presumptive endoderm3.95e-11118
digestive system1.07e-10116
digestive tract1.07e-10116
primitive gut1.07e-10116
intestinal mucosa3.27e-1013
anatomical wall3.27e-1013
wall of intestine3.27e-1013
gastrointestinal system mucosa3.27e-1013
abdomen element5.16e-1049
abdominal segment element5.16e-1049
abdominal segment of trunk5.16e-1049
abdomen5.16e-1049
subdivision of digestive tract8.87e-10114
organ component layer5.91e-0824
epithelium of mucosa2.08e-079
gastrointestinal system epithelium2.08e-079
intestinal epithelium2.08e-079
gut epithelium5.30e-0755


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.15.40056
MA0004.10.563304
MA0006.10.630914
MA0007.11.11209
MA0009.10.519036
MA0014.13.01742
MA0017.17.22336
MA0019.10.591638
MA0024.10.457425
MA0025.10.332323
MA0027.11.63967
MA0028.11.21059
MA0029.10.138094
MA0030.10.141597
MA0031.10.389494
MA0038.10.38168
MA0040.10.182227
MA0041.10.0307631
MA0042.10.0265008
MA0043.10.663757
MA0046.11.70643
MA0048.11.01969
MA0050.10.0864838
MA0051.10.176378
MA0052.11.04725
MA0055.10.20742
MA0056.10
MA0057.10.70933
MA0058.10.494826
MA0059.10.536299
MA0060.11.59503
MA0061.11.036
MA0063.10
MA0066.10.649826
MA0067.10.418736
MA0068.10.0638055
MA0069.10.549379
MA0070.10.18145
MA0071.10.681287
MA0072.10.52298
MA0073.10.00224656
MA0074.10.128541
MA0076.10.12985
MA0077.10.163796
MA0078.10.208148
MA0081.10.223237
MA0083.10.662528
MA0084.10.70101
MA0087.11.12603
MA0088.10.3515
MA0089.10
MA0090.10.269106
MA0091.10.603202
MA0092.10.130972
MA0093.10.721261
MA0095.10
MA0098.10
MA0100.10.286338
MA0101.10.567265
MA0103.10.57731
MA0105.10.833589
MA0106.10.215981
MA0107.10.363138
MA0108.20.638844
MA0109.10
MA0111.10.145795
MA0113.10.419654
MA0114.18.79238
MA0115.12.70381
MA0116.10.86391
MA0117.10.618524
MA0119.10.827692
MA0122.10.229146
MA0124.10.376587
MA0125.10.857327
MA0130.10
MA0131.10.582401
MA0132.10
MA0133.10
MA0135.10.260154
MA0136.10.036462
MA0139.11.01259
MA0140.10.528817
MA0141.11.93839
MA0142.10.370822
MA0143.10.449434
MA0144.10.164354
MA0145.11.62297
MA0146.11.86089
MA0147.10.655028
MA0148.10.369033
MA0149.10.0972631
MA0062.20.0312769
MA0035.20.540369
MA0039.22.03274
MA0138.20.268074
MA0002.20.624244
MA0137.20.263861
MA0104.20.718214
MA0047.20.0436413
MA0112.20.675866
MA0065.25.85929
MA0150.10.305334
MA0151.10
MA0152.10.167612
MA0153.12.93372
MA0154.10.992452
MA0155.11.43989
MA0156.10.0553208
MA0157.10.330817
MA0158.10
MA0159.10.211707
MA0160.11.6988
MA0161.10
MA0162.10.857656
MA0163.11.29806
MA0164.10.609076
MA0080.20.0142719
MA0018.20.634249
MA0099.20.0753229
MA0079.21.17563
MA0102.20.74879
MA0258.11.16782
MA0259.11.05375
MA0442.10
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