MCL coexpression mm9:175
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0019752 | carboxylic acid metabolic process | 0.0287311660886267 |
GO:0006082 | organic acid metabolic process | 0.0287311660886267 |
GO:0005739 | mitochondrion | 0.0287311660886267 |
GO:0044444 | cytoplasmic part | 0.0287311660886267 |
GO:0016491 | oxidoreductase activity | 0.0287311660886267 |
GO:0042579 | microbody | 0.0287311660886267 |
GO:0005777 | peroxisome | 0.0287311660886267 |
GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors | 0.0287311660886267 |
GO:0032787 | monocarboxylic acid metabolic process | 0.0287311660886267 |
GO:0006725 | aromatic compound metabolic process | 0.0303248781022298 |
GO:0004040 | amidase activity | 0.0303248781022298 |
GO:0009397 | folic acid and derivative catabolic process | 0.0303248781022298 |
GO:0046899 | nucleoside triphosphate adenylate kinase activity | 0.0303248781022298 |
GO:0046113 | nucleobase catabolic process | 0.0303248781022298 |
GO:0042720 | mitochondrial inner membrane peptidase complex | 0.0303248781022298 |
GO:0035229 | positive regulation of glutamate-cysteine ligase activity | 0.0303248781022298 |
GO:0004244 | mitochondrial inner membrane peptidase activity | 0.0303248781022298 |
GO:0009258 | 10-formyltetrahydrofolate catabolic process | 0.0303248781022298 |
GO:0035226 | glutamate-cysteine ligase catalytic subunit binding | 0.0303248781022298 |
GO:0017113 | dihydropyrimidine dehydrogenase (NADP+) activity | 0.0303248781022298 |
GO:0006627 | mitochondrial protein processing | 0.0303248781022298 |
GO:0004884 | ecdysteroid hormone receptor activity | 0.0303248781022298 |
GO:0006208 | pyrimidine base catabolic process | 0.0303248781022298 |
GO:0035227 | regulation of glutamate-cysteine ligase activity | 0.0303248781022298 |
GO:0051351 | positive regulation of ligase activity | 0.0303248781022298 |
GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors | 0.0329320261885065 |
GO:0016787 | hydrolase activity | 0.0329320261885065 |
GO:0006732 | coenzyme metabolic process | 0.0329320261885065 |
GO:0006631 | fatty acid metabolic process | 0.0329320261885065 |
GO:0048037 | cofactor binding | 0.0329320261885065 |
GO:0051882 | mitochondrial depolarization | 0.0329320261885065 |
GO:0004765 | shikimate kinase activity | 0.0329320261885065 |
GO:0004357 | glutamate-cysteine ligase activity | 0.0329320261885065 |
GO:0000774 | adenyl-nucleotide exchange factor activity | 0.0329320261885065 |
GO:0003986 | acetyl-CoA hydrolase activity | 0.0329320261885065 |
GO:0051340 | regulation of ligase activity | 0.0329320261885065 |
GO:0016649 | oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor | 0.0329320261885065 |
GO:0004301 | epoxide hydrolase activity | 0.0329320261885065 |
GO:0051900 | regulation of mitochondrial depolarization | 0.0329320261885065 |
GO:0017109 | glutamate-cysteine ligase complex | 0.0329320261885065 |
GO:0004174 | electron-transferring-flavoprotein dehydrogenase activity | 0.0329320261885065 |
GO:0016554 | cytidine to uridine editing | 0.0329320261885065 |
GO:0004756 | selenide, water dikinase activity | 0.0329320261885065 |
GO:0009256 | 10-formyltetrahydrofolate metabolic process | 0.0329320261885065 |
GO:0016155 | formyltetrahydrofolate dehydrogenase activity | 0.0329320261885065 |
GO:0016781 | phosphotransferase activity, paired acceptors | 0.0329320261885065 |
GO:0005737 | cytoplasm | 0.0352784346436778 |
GO:0031975 | envelope | 0.0405402885649097 |
GO:0031967 | organelle envelope | 0.0405402885649097 |
GO:0051186 | cofactor metabolic process | 0.0405402885649097 |
GO:0050660 | FAD binding | 0.0405402885649097 |
GO:0004240 | mitochondrial processing peptidase activity | 0.0405402885649097 |
GO:0051881 | regulation of mitochondrial membrane potential | 0.0405402885649097 |
GO:0016803 | ether hydrolase activity | 0.0405402885649097 |
GO:0016553 | base conversion or substitution editing | 0.0405402885649097 |
GO:0004463 | leukotriene-A4 hydrolase activity | 0.0405402885649097 |
GO:0046983 | protein dimerization activity | 0.0419437696077455 |
GO:0046483 | heterocycle metabolic process | 0.0470481888015543 |
GO:0007005 | mitochondrion organization and biogenesis | 0.0476185188395778 |
GO:0003997 | acyl-CoA oxidase activity | 0.0495782494533212 |
GO:0004558 | alpha-glucosidase activity | 0.0495782494533212 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
intestinal epithelial cell | 2.08e-07 | 9 |
epithelial cell of alimentary canal | 2.08e-07 | 9 |
epithelial cell | 7.06e-07 | 25 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 5.40056 |
MA0004.1 | 0.563304 |
MA0006.1 | 0.630914 |
MA0007.1 | 1.11209 |
MA0009.1 | 0.519036 |
MA0014.1 | 3.01742 |
MA0017.1 | 7.22336 |
MA0019.1 | 0.591638 |
MA0024.1 | 0.457425 |
MA0025.1 | 0.332323 |
MA0027.1 | 1.63967 |
MA0028.1 | 1.21059 |
MA0029.1 | 0.138094 |
MA0030.1 | 0.141597 |
MA0031.1 | 0.389494 |
MA0038.1 | 0.38168 |
MA0040.1 | 0.182227 |
MA0041.1 | 0.0307631 |
MA0042.1 | 0.0265008 |
MA0043.1 | 0.663757 |
MA0046.1 | 1.70643 |
MA0048.1 | 1.01969 |
MA0050.1 | 0.0864838 |
MA0051.1 | 0.176378 |
MA0052.1 | 1.04725 |
MA0055.1 | 0.20742 |
MA0056.1 | 0 |
MA0057.1 | 0.70933 |
MA0058.1 | 0.494826 |
MA0059.1 | 0.536299 |
MA0060.1 | 1.59503 |
MA0061.1 | 1.036 |
MA0063.1 | 0 |
MA0066.1 | 0.649826 |
MA0067.1 | 0.418736 |
MA0068.1 | 0.0638055 |
MA0069.1 | 0.549379 |
MA0070.1 | 0.18145 |
MA0071.1 | 0.681287 |
MA0072.1 | 0.52298 |
MA0073.1 | 0.00224656 |
MA0074.1 | 0.128541 |
MA0076.1 | 0.12985 |
MA0077.1 | 0.163796 |
MA0078.1 | 0.208148 |
MA0081.1 | 0.223237 |
MA0083.1 | 0.662528 |
MA0084.1 | 0.70101 |
MA0087.1 | 1.12603 |
MA0088.1 | 0.3515 |
MA0089.1 | 0 |
MA0090.1 | 0.269106 |
MA0091.1 | 0.603202 |
MA0092.1 | 0.130972 |
MA0093.1 | 0.721261 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.286338 |
MA0101.1 | 0.567265 |
MA0103.1 | 0.57731 |
MA0105.1 | 0.833589 |
MA0106.1 | 0.215981 |
MA0107.1 | 0.363138 |
MA0108.2 | 0.638844 |
MA0109.1 | 0 |
MA0111.1 | 0.145795 |
MA0113.1 | 0.419654 |
MA0114.1 | 8.79238 |
MA0115.1 | 2.70381 |
MA0116.1 | 0.86391 |
MA0117.1 | 0.618524 |
MA0119.1 | 0.827692 |
MA0122.1 | 0.229146 |
MA0124.1 | 0.376587 |
MA0125.1 | 0.857327 |
MA0130.1 | 0 |
MA0131.1 | 0.582401 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.260154 |
MA0136.1 | 0.036462 |
MA0139.1 | 1.01259 |
MA0140.1 | 0.528817 |
MA0141.1 | 1.93839 |
MA0142.1 | 0.370822 |
MA0143.1 | 0.449434 |
MA0144.1 | 0.164354 |
MA0145.1 | 1.62297 |
MA0146.1 | 1.86089 |
MA0147.1 | 0.655028 |
MA0148.1 | 0.369033 |
MA0149.1 | 0.0972631 |
MA0062.2 | 0.0312769 |
MA0035.2 | 0.540369 |
MA0039.2 | 2.03274 |
MA0138.2 | 0.268074 |
MA0002.2 | 0.624244 |
MA0137.2 | 0.263861 |
MA0104.2 | 0.718214 |
MA0047.2 | 0.0436413 |
MA0112.2 | 0.675866 |
MA0065.2 | 5.85929 |
MA0150.1 | 0.305334 |
MA0151.1 | 0 |
MA0152.1 | 0.167612 |
MA0153.1 | 2.93372 |
MA0154.1 | 0.992452 |
MA0155.1 | 1.43989 |
MA0156.1 | 0.0553208 |
MA0157.1 | 0.330817 |
MA0158.1 | 0 |
MA0159.1 | 0.211707 |
MA0160.1 | 1.6988 |
MA0161.1 | 0 |
MA0162.1 | 0.857656 |
MA0163.1 | 1.29806 |
MA0164.1 | 0.609076 |
MA0080.2 | 0.0142719 |
MA0018.2 | 0.634249 |
MA0099.2 | 0.0753229 |
MA0079.2 | 1.17563 |
MA0102.2 | 0.74879 |
MA0258.1 | 1.16782 |
MA0259.1 | 1.05375 |
MA0442.1 | 0 |