MCL coexpression mm9:374
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr15:25914217..25914232,+ | p3@Zfp622 |
Mm9::chr17:36005563..36005592,+ | p@chr17:36005563..36005592 + |
Mm9::chr19:36422775..36422803,+ | p5@Pcgf5 |
Mm9::chr19:36422807..36422843,+ | p2@Pcgf5 |
Mm9::chr19:36424066..36424074,+ | p@chr19:36424066..36424074 + |
Mm9::chr1:89516881..89516898,+ | p2@Inpp5d |
Mm9::chr4:102243160..102243173,+ | p7@Pde4b |
Mm9::chr4:102243191..102243223,+ | p1@Pde4b |
Mm9::chr4:102258666..102258669,+ | p@chr4:102258666..102258669 + |
Mm9::chr4:120689752..120689804,- | p2@Smap2 |
Mm9::chr4:140255901..140255913,+ | p@chr4:140255901..140255913 + |
Mm9::chr6:124679957..124679972,- | p@chr6:124679957..124679972 - |
Mm9::chr6:128789641..128789666,- | p@chr6:128789641..128789666 - |
Mm9::chr6:87800966..87800977,- | p2@Cnbp |
Mm9::chr8:26311787..26311816,- | p4@Tacc1 |
Mm9::chr8:86773565..86773580,- | p2@D8Ertd738e |
Mm9::chr9:64659258..64659283,+ | p1@Dennd4a |
Mm9::chr9:64659291..64659310,+ | p2@Dennd4a |
Mm9::chr9:64659311..64659314,+ | p6@Dennd4a |
Mm9::chr9:64659338..64659345,+ | p5@Dennd4a |
Mm9::chrX:12649180..12649195,+ | p@chrX:12649180..12649195 + |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0045659 | negative regulation of neutrophil differentiation | 0.0121075987508903 |
GO:0045658 | regulation of neutrophil differentiation | 0.0121075987508903 |
GO:0030852 | regulation of granulocyte differentiation | 0.0121075987508903 |
GO:0045656 | negative regulation of monocyte differentiation | 0.0121075987508903 |
GO:0045655 | regulation of monocyte differentiation | 0.0121075987508903 |
GO:0030853 | negative regulation of granulocyte differentiation | 0.0121075987508903 |
GO:0045409 | negative regulation of interleukin-6 biosynthetic process | 0.0121075987508903 |
GO:0030223 | neutrophil differentiation | 0.0211848151878558 |
GO:0030224 | monocyte differentiation | 0.0282417775969532 |
GO:0045779 | negative regulation of bone resorption | 0.0302242529538034 |
GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity | 0.0302242529538034 |
GO:0045579 | positive regulation of B cell differentiation | 0.0302242529538034 |
GO:0045648 | positive regulation of erythrocyte differentiation | 0.0302242529538034 |
GO:0050777 | negative regulation of immune response | 0.0302242529538034 |
GO:0002683 | negative regulation of immune system process | 0.0302242529538034 |
GO:0045124 | regulation of bone resorption | 0.0302242529538034 |
GO:0030851 | granulocyte differentiation | 0.0302242529538034 |
GO:0008340 | determination of adult life span | 0.0302242529538034 |
GO:0008270 | zinc ion binding | 0.0302242529538034 |
GO:0030889 | negative regulation of B cell proliferation | 0.0302242529538034 |
GO:0045671 | negative regulation of osteoclast differentiation | 0.0302242529538034 |
GO:0002762 | negative regulation of myeloid leukocyte differentiation | 0.0302242529538034 |
GO:0045408 | regulation of interleukin-6 biosynthetic process | 0.0302242529538034 |
GO:0045577 | regulation of B cell differentiation | 0.0302242529538034 |
GO:0045646 | regulation of erythrocyte differentiation | 0.0302242529538034 |
GO:0010259 | multicellular organismal aging | 0.0302242529538034 |
GO:0042036 | negative regulation of cytokine biosynthetic process | 0.0302242529538034 |
GO:0042226 | interleukin-6 biosynthetic process | 0.0302242529538034 |
GO:0050869 | negative regulation of B cell activation | 0.032094965763412 |
GO:0042578 | phosphoric ester hydrolase activity | 0.0343631409171035 |
GO:0045639 | positive regulation of myeloid cell differentiation | 0.0343631409171035 |
GO:0046851 | negative regulation of bone remodeling | 0.0343631409171035 |
GO:0045621 | positive regulation of lymphocyte differentiation | 0.0358917949791537 |
GO:0045453 | bone resorption | 0.0358917949791537 |
GO:0045670 | regulation of osteoclast differentiation | 0.0358917949791537 |
GO:0042127 | regulation of cell proliferation | 0.0358917949791537 |
GO:0032635 | interleukin-6 production | 0.0358917949791537 |
GO:0046914 | transition metal ion binding | 0.0358917949791537 |
GO:0002761 | regulation of myeloid leukocyte differentiation | 0.0382274712110252 |
GO:0050672 | negative regulation of lymphocyte proliferation | 0.0382274712110252 |
GO:0032945 | negative regulation of mononuclear cell proliferation | 0.0382274712110252 |
GO:0045638 | negative regulation of myeloid cell differentiation | 0.0382274712110252 |
GO:0030316 | osteoclast differentiation | 0.0392971843375408 |
GO:0030888 | regulation of B cell proliferation | 0.0403176442248182 |
GO:0006695 | cholesterol biosynthetic process | 0.0406397771232482 |
GO:0045619 | regulation of lymphocyte differentiation | 0.0406397771232482 |
GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity | 0.0406397771232482 |
GO:0017148 | negative regulation of translation | 0.0406397771232482 |
GO:0051250 | negative regulation of lymphocyte activation | 0.0406397771232482 |
GO:0001894 | tissue homeostasis | 0.0406397771232482 |
GO:0031327 | negative regulation of cellular biosynthetic process | 0.0406397771232482 |
GO:0048871 | multicellular organismal homeostasis | 0.0406397771232482 |
GO:0004112 | cyclic-nucleotide phosphodiesterase activity | 0.0406397771232482 |
GO:0050871 | positive regulation of B cell activation | 0.0406397771232482 |
GO:0042100 | B cell proliferation | 0.0414287135628179 |
GO:0007568 | aging | 0.0414670987599829 |
GO:0051241 | negative regulation of multicellular organismal process | 0.0414670987599829 |
GO:0046850 | regulation of bone remodeling | 0.0414670987599829 |
GO:0016126 | sterol biosynthetic process | 0.0414670987599829 |
GO:0004437 | inositol or phosphatidylinositol phosphatase activity | 0.0421751190266734 |
GO:0009890 | negative regulation of biosynthetic process | 0.0439822517988457 |
GO:0008283 | cell proliferation | 0.0439822517988457 |
GO:0045637 | regulation of myeloid cell differentiation | 0.0460911603436185 |
GO:0030183 | B cell differentiation | 0.0460911603436185 |
GO:0030218 | erythrocyte differentiation | 0.0472329066675493 |
GO:0050864 | regulation of B cell activation | 0.0472329066675493 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
lymphoid lineage restricted progenitor cell | 1.69e-08 | 12 |
T cell | 7.95e-08 | 11 |
pro-T cell | 7.95e-08 | 11 |
lymphocyte | 3.29e-07 | 13 |
common lymphoid progenitor | 3.29e-07 | 13 |
hematopoietic cell | 5.55e-07 | 32 |
hematopoietic oligopotent progenitor cell | 5.55e-07 | 32 |
hematopoietic stem cell | 5.55e-07 | 32 |
angioblastic mesenchymal cell | 5.55e-07 | 32 |
hematopoietic multipotent progenitor cell | 5.55e-07 | 32 |
mature alpha-beta T cell | 7.89e-07 | 9 |
alpha-beta T cell | 7.89e-07 | 9 |
immature T cell | 7.89e-07 | 9 |
mature T cell | 7.89e-07 | 9 |
immature alpha-beta T cell | 7.89e-07 | 9 |
Ontology term | p-value | n |
---|---|---|
hemolymphoid system | 1.18e-09 | 48 |
immune system | 1.18e-09 | 48 |
mixed endoderm/mesoderm-derived structure | 2.75e-09 | 35 |
hemopoietic organ | 3.08e-09 | 29 |
immune organ | 3.08e-09 | 29 |
hematopoietic system | 6.55e-09 | 45 |
blood island | 6.55e-09 | 45 |
lateral plate mesoderm | 7.74e-09 | 87 |
thymus | 6.85e-08 | 23 |
neck | 6.85e-08 | 23 |
respiratory system epithelium | 6.85e-08 | 23 |
hemolymphoid system gland | 6.85e-08 | 23 |
pharyngeal epithelium | 6.85e-08 | 23 |
thymic region | 6.85e-08 | 23 |
pharyngeal gland | 6.85e-08 | 23 |
entire pharyngeal arch endoderm | 6.85e-08 | 23 |
thymus primordium | 6.85e-08 | 23 |
early pharyngeal endoderm | 6.85e-08 | 23 |
pharynx | 1.27e-07 | 24 |
gland of gut | 1.27e-07 | 24 |
upper respiratory tract | 1.27e-07 | 24 |
chordate pharynx | 1.27e-07 | 24 |
pharyngeal arch system | 1.27e-07 | 24 |
pharyngeal region of foregut | 1.27e-07 | 24 |
respiratory tract | 4.86e-07 | 41 |
respiratory system | 6.57e-07 | 42 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 1.99833 |
MA0004.1 | 0.470639 |
MA0006.1 | 0.224339 |
MA0007.1 | 0.145624 |
MA0009.1 | 0.499857 |
MA0014.1 | 0.643452 |
MA0017.1 | 0.074682 |
MA0019.1 | 0.344318 |
MA0024.1 | 0.461433 |
MA0025.1 | 0.712532 |
MA0027.1 | 2.09948 |
MA0028.1 | 1.83592 |
MA0029.1 | 0.442582 |
MA0030.1 | 0.448261 |
MA0031.1 | 1.07215 |
MA0038.1 | 2.03003 |
MA0040.1 | 0.510947 |
MA0041.1 | 0.353863 |
MA0042.1 | 0.334544 |
MA0043.1 | 0.586618 |
MA0046.1 | 0.531807 |
MA0048.1 | 0.638726 |
MA0050.1 | 0.180744 |
MA0051.1 | 0.263603 |
MA0052.1 | 0.518112 |
MA0055.1 | 0.70871 |
MA0056.1 | 0 |
MA0057.1 | 2.77102 |
MA0058.1 | 0.666793 |
MA0059.1 | 0.698078 |
MA0060.1 | 1.73264 |
MA0061.1 | 1.46405 |
MA0063.1 | 0 |
MA0066.1 | 1.28459 |
MA0067.1 | 0.817149 |
MA0068.1 | 3.33497 |
MA0069.1 | 1.2887 |
MA0070.1 | 0.509795 |
MA0071.1 | 0.180178 |
MA0072.1 | 0.502282 |
MA0073.1 | 8.93301 |
MA0074.1 | 0.222108 |
MA0076.1 | 0.597322 |
MA0077.1 | 0.48317 |
MA0078.1 | 0.289095 |
MA0081.1 | 0.757603 |
MA0083.1 | 0.585897 |
MA0084.1 | 1.1333 |
MA0087.1 | 0.546952 |
MA0088.1 | 1.3976 |
MA0089.1 | 0 |
MA0090.1 | 0.825782 |
MA0091.1 | 0.163657 |
MA0092.1 | 0.417266 |
MA0093.1 | 0.531479 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.213782 |
MA0101.1 | 0.720996 |
MA0103.1 | 0.0799057 |
MA0105.1 | 3.54553 |
MA0106.1 | 0.800883 |
MA0107.1 | 0.561777 |
MA0108.2 | 0.363107 |
MA0109.1 | 0 |
MA0111.1 | 1.39174 |
MA0113.1 | 0.273246 |
MA0114.1 | 0.0414319 |
MA0115.1 | 0.589161 |
MA0116.1 | 0.486423 |
MA0117.1 | 0.559943 |
MA0119.1 | 0.110503 |
MA0122.1 | 0.577888 |
MA0124.1 | 0.766819 |
MA0125.1 | 0.697415 |
MA0130.1 | 0 |
MA0131.1 | 0.340612 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.5028 |
MA0136.1 | 0.666439 |
MA0139.1 | 0.463408 |
MA0140.1 | 0.2137 |
MA0141.1 | 0.301299 |
MA0142.1 | 0.40532 |
MA0143.1 | 0.285913 |
MA0144.1 | 0.0425459 |
MA0145.1 | 0.416713 |
MA0146.1 | 0.611484 |
MA0147.1 | 0.708858 |
MA0148.1 | 0.165681 |
MA0149.1 | 0.113293 |
MA0062.2 | 1.22637 |
MA0035.2 | 0.217072 |
MA0039.2 | 3.34265 |
MA0138.2 | 0.334152 |
MA0002.2 | 0.10237 |
MA0137.2 | 0.297219 |
MA0104.2 | 0.826656 |
MA0047.2 | 0.256234 |
MA0112.2 | 0.0180044 |
MA0065.2 | 0.418537 |
MA0150.1 | 0.145553 |
MA0151.1 | 0 |
MA0152.1 | 0.712054 |
MA0153.1 | 0.635107 |
MA0154.1 | 0.10741 |
MA0155.1 | 0.996232 |
MA0156.1 | 1.00164 |
MA0157.1 | 0.378326 |
MA0158.1 | 0 |
MA0159.1 | 0.743892 |
MA0160.1 | 0.167661 |
MA0161.1 | 0 |
MA0162.1 | 2.42839 |
MA0163.1 | 2.26653 |
MA0164.1 | 0.23692 |
MA0080.2 | 0.563938 |
MA0018.2 | 0.244112 |
MA0099.2 | 0.329046 |
MA0079.2 | 7.94611 |
MA0102.2 | 1.18455 |
MA0258.1 | 0.0367249 |
MA0259.1 | 0.165891 |
MA0442.1 | 0 |