MCL coexpression mm9:166
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0004144 | diacylglycerol O-acyltransferase activity | 0.00174125250254486 |
GO:0006639 | acylglycerol metabolic process | 0.00174125250254486 |
GO:0046486 | glycerolipid metabolic process | 0.00174125250254486 |
GO:0006638 | neutral lipid metabolic process | 0.00174125250254486 |
GO:0006662 | glycerol ether metabolic process | 0.00174125250254486 |
GO:0003846 | 2-acylglycerol O-acyltransferase activity | 0.00179856005864711 |
GO:0032787 | monocarboxylic acid metabolic process | 0.00374434532675187 |
GO:0046460 | neutral lipid biosynthetic process | 0.00374434532675187 |
GO:0016832 | aldehyde-lyase activity | 0.00374434532675187 |
GO:0046463 | acylglycerol biosynthetic process | 0.00374434532675187 |
GO:0046504 | glycerol ether biosynthetic process | 0.00374434532675187 |
GO:0045017 | glycerolipid biosynthetic process | 0.00374434532675187 |
GO:0016491 | oxidoreductase activity | 0.00374434532675187 |
GO:0003707 | steroid hormone receptor activity | 0.00374434532675187 |
GO:0004879 | ligand-dependent nuclear receptor activity | 0.00374434532675187 |
GO:0015293 | symporter activity | 0.00416216468050081 |
GO:0005624 | membrane fraction | 0.00667373808695119 |
GO:0016411 | acylglycerol O-acyltransferase activity | 0.00770460423265143 |
GO:0022804 | active transmembrane transporter activity | 0.00953023842497523 |
GO:0015291 | secondary active transmembrane transporter activity | 0.00953023842497523 |
GO:0000267 | cell fraction | 0.00953023842497523 |
GO:0044255 | cellular lipid metabolic process | 0.0101111549460318 |
GO:0006641 | triacylglycerol metabolic process | 0.0124823647578902 |
GO:0006071 | glycerol metabolic process | 0.0124823647578902 |
GO:0019751 | polyol metabolic process | 0.0124823647578902 |
GO:0042579 | microbody | 0.0124823647578902 |
GO:0005777 | peroxisome | 0.0124823647578902 |
GO:0006629 | lipid metabolic process | 0.0165168601474546 |
GO:0006091 | generation of precursor metabolites and energy | 0.0206997934162585 |
GO:0008374 | O-acyltransferase activity | 0.0212606019526577 |
GO:0008430 | selenium binding | 0.0212606019526577 |
GO:0009791 | post-embryonic development | 0.0212606019526577 |
GO:0019752 | carboxylic acid metabolic process | 0.0212606019526577 |
GO:0006082 | organic acid metabolic process | 0.0212606019526577 |
GO:0008115 | sarcosine oxidase activity | 0.0212606019526577 |
GO:0004139 | deoxyribose-phosphate aldolase activity | 0.0212606019526577 |
GO:0050031 | L-pipecolate oxidase activity | 0.0212606019526577 |
GO:0032682 | negative regulation of chemokine production | 0.0212606019526577 |
GO:0001887 | selenium metabolic process | 0.0212606019526577 |
GO:0008336 | gamma-butyrobetaine dioxygenase activity | 0.0212606019526577 |
GO:0046653 | tetrahydrofolate metabolic process | 0.0212606019526577 |
GO:0032642 | regulation of chemokine production | 0.0212606019526577 |
GO:0008520 | L-ascorbate:sodium symporter activity | 0.0212606019526577 |
GO:0005783 | endoplasmic reticulum | 0.0228979929338124 |
GO:0016830 | carbon-carbon lyase activity | 0.0269041737485365 |
GO:0015370 | solute:sodium symporter activity | 0.0291277756736434 |
GO:0016829 | lyase activity | 0.033874784032441 |
GO:0006118 | electron transport | 0.033874784032441 |
GO:0002318 | myeloid progenitor cell differentiation | 0.033874784032441 |
GO:0045730 | respiratory burst | 0.033874784032441 |
GO:0045329 | carnitine biosynthetic process | 0.033874784032441 |
GO:0006089 | lactate metabolic process | 0.033874784032441 |
GO:0035166 | post-embryonic hemopoiesis | 0.033874784032441 |
GO:0006732 | coenzyme metabolic process | 0.033874784032441 |
GO:0015294 | solute:cation symporter activity | 0.0407867671654657 |
GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor | 0.0434478032946142 |
GO:0050327 | testosterone 17-beta-dehydrogenase activity | 0.0434478032946142 |
GO:0012507 | ER to Golgi transport vesicle membrane | 0.0434478032946142 |
GO:0030134 | ER to Golgi transport vesicle | 0.0434478032946142 |
GO:0015760 | glucose-6-phosphate transport | 0.0434478032946142 |
GO:0030127 | COPII vesicle coat | 0.0434478032946142 |
GO:0004165 | dodecenoyl-CoA delta-isomerase activity | 0.0434478032946142 |
GO:0004800 | thyroxine 5'-deiodinase activity | 0.0434478032946142 |
GO:0051186 | cofactor metabolic process | 0.0446139464425043 |
GO:0044249 | cellular biosynthetic process | 0.0446139464425043 |
GO:0006790 | sulfur metabolic process | 0.0449109058718855 |
GO:0008643 | carbohydrate transport | 0.0471450283721544 |
GO:0009058 | biosynthetic process | 0.0472297746847424 |
GO:0019432 | triacylglycerol biosynthetic process | 0.0479739257451353 |
GO:0009133 | nucleoside diphosphate biosynthetic process | 0.0479739257451353 |
GO:0001780 | neutrophil homeostasis | 0.0479739257451353 |
GO:0006651 | diacylglycerol biosynthetic process | 0.0479739257451353 |
GO:0009437 | carnitine metabolic process | 0.0479739257451353 |
GO:0004300 | enoyl-CoA hydratase activity | 0.0479739257451353 |
GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity | 0.0479739257451353 |
GO:0009264 | deoxyribonucleotide catabolic process | 0.0479739257451353 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
intestinal epithelial cell | 2.15e-07 | 9 |
epithelial cell of alimentary canal | 2.15e-07 | 9 |
epithelial cell | 5.62e-07 | 25 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.000458662 |
MA0004.1 | 0.483795 |
MA0006.1 | 0.0219464 |
MA0007.1 | 0.442865 |
MA0009.1 | 0.474142 |
MA0014.1 | 0.00245484 |
MA0017.1 | 9.17255 |
MA0019.1 | 0.248387 |
MA0024.1 | 0.132989 |
MA0025.1 | 0.308048 |
MA0027.1 | 1.60586 |
MA0028.1 | 0.386398 |
MA0029.1 | 0.386539 |
MA0030.1 | 2.51856 |
MA0031.1 | 0.710815 |
MA0038.1 | 1.81877 |
MA0040.1 | 0.491598 |
MA0041.1 | 0.293292 |
MA0042.1 | 0.648059 |
MA0043.1 | 0.21448 |
MA0046.1 | 1.59725 |
MA0048.1 | 0.0834119 |
MA0050.1 | 0.596343 |
MA0051.1 | 0.347052 |
MA0052.1 | 0.502954 |
MA0055.1 | 0.00217501 |
MA0056.1 | 0 |
MA0057.1 | 0.0619361 |
MA0058.1 | 0.620235 |
MA0059.1 | 0.450808 |
MA0060.1 | 1.10059 |
MA0061.1 | 0.326599 |
MA0063.1 | 0 |
MA0066.1 | 0.133917 |
MA0067.1 | 0.392359 |
MA0068.1 | 0.244308 |
MA0069.1 | 0.168415 |
MA0070.1 | 0.162867 |
MA0071.1 | 0.593819 |
MA0072.1 | 0.477946 |
MA0073.1 | 0.0149343 |
MA0074.1 | 0.260675 |
MA0076.1 | 0.73109 |
MA0077.1 | 0.146146 |
MA0078.1 | 0.179451 |
MA0081.1 | 0.0824205 |
MA0083.1 | 0.213975 |
MA0084.1 | 0.670595 |
MA0087.1 | 0.187238 |
MA0088.1 | 0.0808262 |
MA0089.1 | 0 |
MA0090.1 | 1.56891 |
MA0091.1 | 0.306768 |
MA0092.1 | 0.393365 |
MA0093.1 | 0.604405 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.461027 |
MA0101.1 | 0.29618 |
MA0103.1 | 0.940131 |
MA0105.1 | 0.269283 |
MA0106.1 | 0.416802 |
MA0107.1 | 0.458425 |
MA0108.2 | 0.97311 |
MA0109.1 | 0 |
MA0111.1 | 0.666252 |
MA0113.1 | 0.368016 |
MA0114.1 | 13.8665 |
MA0115.1 | 1.16182 |
MA0116.1 | 0.121772 |
MA0117.1 | 0.196027 |
MA0119.1 | 2.9327 |
MA0122.1 | 0.208382 |
MA0124.1 | 0.351161 |
MA0125.1 | 0.296313 |
MA0130.1 | 0 |
MA0131.1 | 0.522025 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.238187 |
MA0136.1 | 1.23052 |
MA0139.1 | 0.344063 |
MA0140.1 | 1.09173 |
MA0141.1 | 0.217655 |
MA0142.1 | 0.10126 |
MA0143.1 | 0.396005 |
MA0144.1 | 0.329188 |
MA0145.1 | 1.11392 |
MA0146.1 | 0.00206335 |
MA0147.1 | 0.143959 |
MA0148.1 | 1.50616 |
MA0149.1 | 0.00428198 |
MA0062.2 | 1.3248 |
MA0035.2 | 0.471578 |
MA0039.2 | 0.0236984 |
MA0138.2 | 0.235161 |
MA0002.2 | 0.356875 |
MA0137.2 | 0.772738 |
MA0104.2 | 0.0619029 |
MA0047.2 | 1.34926 |
MA0112.2 | 0.937215 |
MA0065.2 | 5.89372 |
MA0150.1 | 1.31804 |
MA0151.1 | 0 |
MA0152.1 | 0.331417 |
MA0153.1 | 3.65414 |
MA0154.1 | 0.489275 |
MA0155.1 | 0.152658 |
MA0156.1 | 1.60958 |
MA0157.1 | 1.02801 |
MA0158.1 | 0 |
MA0159.1 | 0.411392 |
MA0160.1 | 0.815509 |
MA0161.1 | 0 |
MA0162.1 | 0.00125859 |
MA0163.1 | 0.00578082 |
MA0164.1 | 0.536144 |
MA0080.2 | 1.85021 |
MA0018.2 | 0.0317353 |
MA0099.2 | 0.494744 |
MA0079.2 | 0.00360608 |
MA0102.2 | 0.717952 |
MA0258.1 | 0.405729 |
MA0259.1 | 0.125519 |
MA0442.1 | 0 |