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MCL coexpression mm9:2998

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Phase1 CAGE Peaks

 Short description
Mm9::chr15:76028577..76028634,-p4@Plec
Mm9::chr15:77672518..77672553,-p1@Myh9
Mm9::chr15:77672563..77672584,-p2@Myh9


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0032796uropod organization and biogenesis0.00205445680162165
GO:0051295establishment of meiotic spindle localization0.00205445680162165
GO:0051293establishment of spindle localization0.00205445680162165
GO:0051653spindle localization0.00205445680162165
GO:0007132meiotic metaphase I0.00205445680162165
GO:0043531ADP binding0.00205445680162165
GO:0001768establishment of T cell polarity0.00205445680162165
GO:0001767establishment of lymphocyte polarity0.00205445680162165
GO:0000212meiotic spindle organization and biogenesis0.00273927573549553
GO:0030898actin-dependent ATPase activity0.00316070277172562
GO:0031254trailing edge0.00316070277172562
GO:0000146microfilament motor activity0.00316070277172562
GO:0001931uropod0.00316070277172562
GO:0051323metaphase0.00338381120267096
GO:0014902myotube differentiation0.00338381120267096
GO:0000768syncytium formation by plasma membrane fusion0.00338381120267096
GO:0007520myoblast fusion0.00338381120267096
GO:0006949syncytium formation0.00365236764732738
GO:0031594neuromuscular junction0.00522952640412784
GO:0030010establishment of cell polarity0.00522952640412784
GO:0007051spindle organization and biogenesis0.00522952640412784
GO:0045026plasma membrane fusion0.00522952640412784
GO:0030048actin filament-based movement0.00535945252596953
GO:0030863cortical cytoskeleton0.00582096093792801
GO:0001725stress fiber0.0058320064046034
GO:0032432actin filament bundle0.0058320064046034
GO:0001772immunological synapse0.0058320064046034
GO:0048628myoblast maturation0.0058320064046034
GO:0051656establishment of organelle localization0.0058320064046034
GO:0006944membrane fusion0.0058320064046034
GO:0048627myoblast development0.0058320064046034
GO:0007163establishment and/or maintenance of cell polarity0.00597660160471753
GO:0051015actin filament binding0.00597660160471753
GO:0005913cell-cell adherens junction0.00621889626436825
GO:0051640organelle localization0.00621889626436825
GO:0007127meiosis I0.00621889626436825
GO:0044448cell cortex part0.00621889626436825
GO:0045445myoblast differentiation0.00778530998509257
GO:0005819spindle0.00800711368837157
GO:0022603regulation of anatomical structure morphogenesis0.00898227624895048
GO:0022604regulation of cell morphogenesis0.00898227624895048
GO:0005938cell cortex0.00898227624895048
GO:0008360regulation of cell shape0.00898227624895048
GO:0016459myosin complex0.0106458216084031
GO:0005912adherens junction0.0107334885962274
GO:0042692muscle cell differentiation0.0107334885962274
GO:0048741skeletal muscle fiber development0.0107334885962274
GO:0000226microtubule cytoskeleton organization and biogenesis0.0107334885962274
GO:0048747muscle fiber development0.0107334885962274
GO:0051327M phase of meiotic cell cycle0.0114739474203775
GO:0007126meiosis0.0114739474203775
GO:0048469cell maturation0.0114739474203775
GO:0051321meiotic cell cycle0.0114739474203775
GO:0021700developmental maturation0.013848560662783
GO:0007519skeletal muscle development0.0141944288112041
GO:0030705cytoskeleton-dependent intracellular transport0.0143811976113516
GO:0005516calmodulin binding0.0154264475630538
GO:0042110T cell activation0.0165749396198628
GO:0001701in utero embryonic development0.0165749396198628
GO:0014706striated muscle development0.0167095819865228
GO:0005911intercellular junction0.0202077718192294
GO:0030029actin filament-based process0.0216533224805838
GO:0007517muscle development0.0216533224805838
GO:0007017microtubule-based process0.0225990248178382
GO:0000904cellular morphogenesis during differentiation0.0233042861079471
GO:0046649lymphocyte activation0.0233042861079471
GO:0015629actin cytoskeleton0.0233042861079471
GO:0045321leukocyte activation0.0247725805644814
GO:0016337cell-cell adhesion0.0247725805644814
GO:0001775cell activation0.0253289194720478
GO:0043009chordate embryonic development0.0253289194720478
GO:0009792embryonic development ending in birth or egg hatching0.0253289194720478
GO:0042623ATPase activity, coupled0.0253289194720478
GO:0000279M phase0.0255300498548184
GO:0016044membrane organization and biogenesis0.0255300498548184
GO:0003779actin binding0.0261672918943389
GO:0050793regulation of developmental process0.0270586993384315
GO:0016887ATPase activity0.0270586993384315
GO:0032990cell part morphogenesis0.0270586993384315
GO:0048858cell projection morphogenesis0.0270586993384315
GO:0030030cell projection organization and biogenesis0.0270586993384315
GO:0022403cell cycle phase0.0270586993384315
GO:0015630microtubule cytoskeleton0.0283168503741587
GO:0006928cell motility0.0313244237047254
GO:0051674localization of cell0.0313244237047254
GO:0008092cytoskeletal protein binding0.0319157475228666
GO:0042995cell projection0.0343826333696681
GO:0030054cell junction0.0357662252282315
GO:0017111nucleoside-triphosphatase activity0.04036668968461
GO:0009790embryonic development0.04036668968461
GO:0007010cytoskeleton organization and biogenesis0.04036668968461
GO:0000902cell morphogenesis0.0404899194652934
GO:0032989cellular structure morphogenesis0.0404899194652934
GO:0016462pyrophosphatase activity0.0404899194652934
GO:0016818hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides0.0404899194652934
GO:0016817hydrolase activity, acting on acid anhydrides0.0404899194652934
GO:0044430cytoskeletal part0.0440543314162169
GO:0022402cell cycle process0.0462881695712307
GO:0046907intracellular transport0.0471487459927717
GO:0022610biological adhesion0.0478423999743973
GO:0007155cell adhesion0.0478423999743973



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
multi-potent skeletal muscle stem cell5.26e-079

Uber Anatomy
Ontology termp-valuen
endoderm-derived structure1.10e-10118
endoderm1.10e-10118
presumptive endoderm1.10e-10118
digestive system6.34e-10116
digestive tract6.34e-10116
primitive gut6.34e-10116
subdivision of digestive tract6.53e-10114
mixed endoderm/mesoderm-derived structure4.91e-0935
respiratory tract8.66e-0941
respiratory system1.18e-0842
foregut8.14e-0880
hemolymphoid system1.53e-0748
immune system1.53e-0748
hematopoietic system2.33e-0745
blood island2.33e-0745
hemopoietic organ4.95e-0729
immune organ4.95e-0729
skeletal muscle tissue5.26e-079
striated muscle tissue5.26e-079
muscle tissue5.26e-079
multilaminar epithelium5.26e-079
epithelial vesicle5.26e-079
musculature5.26e-079
somite5.26e-079
myotome5.26e-079
presomitic mesoderm5.26e-079
presumptive segmental plate5.26e-079
dermomyotome5.26e-079
trunk paraxial mesoderm5.26e-079


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.526413
MA0004.10.801718
MA0006.10.60285
MA0007.10.784593
MA0009.11.27673
MA0014.11.33691
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.10.714279
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.10.353763
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.10.190475
MA0056.10
MA0057.10.337566
MA0058.10.690848
MA0059.10.705317
MA0060.10.502699
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.11.69369
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.11.40099
MA0089.10
MA0090.10.762482
MA0091.10.816659
MA0092.10.762845
MA0093.10.62555
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.10.71579
MA0103.10.647985
MA0105.10.405648
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.10.537669
MA0115.11.38041
MA0116.10.602598
MA0117.11.34691
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.10.462282
MA0140.10.898603
MA0141.10.671467
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.10.794492
MA0146.10.151124
MA0147.10.556853
MA0148.10.820161
MA0149.10.722227
MA0062.20.412742
MA0035.20.903829
MA0039.27.73525
MA0138.21.07027
MA0002.20.466067
MA0137.20.668025
MA0104.20.48458
MA0047.20.962424
MA0112.21.44603
MA0065.20.292912
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.35067
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.13.50066
MA0160.10.823568
MA0161.10
MA0162.12.92952
MA0163.10.477233
MA0164.10.933981
MA0080.20.64167
MA0018.20.944669
MA0099.21.06348
MA0079.22.59634
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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