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MCL coexpression mm9:981

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Phase1 CAGE Peaks

 Short description
Mm9::chr1:135027844..135027860,+p2@Ppp1r15b
Mm9::chr1:135027865..135027941,+p1@Ppp1r15b
Mm9::chr1:75165234..75165257,+p1@Zfand2b
Mm9::chr3:131153142..131153199,-p@chr3:131153142..131153199
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Mm9::chr3:88259648..88259655,-p7@Sema4a
Mm9::chr3:96531690..96531717,+p2@Rnf115
Mm9::chr5:106129759..106129771,+p12@Lrrc8d
Mm9::chr5:106129777..106129854,+p2@Lrrc8d


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0000164protein phosphatase type 1 complex0.0170930805894921
GO:0006983ER overload response0.0417110277041303
GO:0042542response to hydrogen peroxide0.0417110277041303
GO:0000302response to reactive oxygen species0.0417110277041303
GO:0033554cellular response to stress0.0417110277041303
GO:0006984ER-nuclear signaling pathway0.0417110277041303
GO:0051716cellular response to stimulus0.0417110277041303
GO:0008287protein serine/threonine phosphatase complex0.0417110277041303
GO:0006446regulation of translational initiation0.0417110277041303



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
gastrointestinal system1.24e-1247
endoderm-derived structure5.40e-12118
endoderm5.40e-12118
presumptive endoderm5.40e-12118
intestine1.03e-1131
digestive system1.43e-11116
digestive tract1.43e-11116
primitive gut1.43e-11116
subdivision of digestive tract9.29e-11114
exocrine gland1.20e-1025
exocrine system1.20e-1025
trunk1.92e-1090
digestive tract diverticulum4.44e-1023
sac4.44e-1023
liver1.48e-0922
epithelial sac1.48e-0922
digestive gland1.48e-0922
epithelium of foregut-midgut junction1.48e-0922
anatomical boundary1.48e-0922
hepatobiliary system1.48e-0922
foregut-midgut junction1.48e-0922
hepatic diverticulum1.48e-0922
liver primordium1.48e-0922
septum transversum1.48e-0922
liver bud1.48e-0922
trunk region element1.97e-0979
organ component layer3.11e-0924
trunk mesenchyme7.51e-0945
abdomen element1.77e-0849
abdominal segment element1.77e-0849
abdominal segment of trunk1.77e-0849
abdomen1.77e-0849
mesenchyme2.29e-0861
entire embryonic mesenchyme2.29e-0861
mucosa3.17e-0815
intestinal mucosa2.92e-0713
anatomical wall2.92e-0713
wall of intestine2.92e-0713
gastrointestinal system mucosa2.92e-0713
subdivision of trunk8.62e-0766


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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