MCL coexpression mm9:649

Phase1 CAGE Peaks

	Short description
Mm9::chr11:17805943..17805945,+	p@chr11:17805943..17805945 +
Mm9::chr13:117839387..117839413,+	p@chr13:117839387..117839413 +
Mm9::chr13:21826924..21826939,+	p8@Hist1h4c p8@Hist1h4d p8@Hist1h4f p8@Hist1h4h p8@Hist1h4i p8@Hist1h4j p8@Hist1h4k p8@Hist1h4m p8@Hist1h4n p9@Hist1h4a p9@Hist1h4b p9@Hist2h4 p9@Hist4h4
Mm9::chr13:21902297..21902311,+	p7@Hist1h2ap
Mm9::chr13:21903606..21903623,+	p6@Hist1h4c p6@Hist1h4d p6@Hist1h4f p6@Hist1h4h p6@Hist1h4i p6@Hist1h4j p6@Hist1h4k p6@Hist1h4m p6@Hist1h4n p7@Hist1h4a p7@Hist1h4b p7@Hist2h4 p7@Hist4h4
Mm9::chr13:21925605..21925620,+	p1@Hist1h2bq p1@Hist1h2br p5@Hist1h2bf p5@Hist1h2bj p5@Hist1h2bl p5@Hist1h2bn
Mm9::chr17:17026218..17026227,+	p@chr17:17026218..17026227 +
Mm9::chr1:129690056..129690058,+	p@chr1:129690056..129690058 +
Mm9::chr3:96049453..96049469,+	p1@Hist2h2aa1 p1@Hist2h2aa2
Mm9::chr3:96050759..96050773,+	p4@Hist2h3c1
Mm9::chr5:74733727..74733734,+	p@chr5:74733727..74733734 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0006334	nucleosome assembly	1.36092384170213e-08
GO:0000786	nucleosome	1.36092384170213e-08
GO:0031497	chromatin assembly	1.36092384170213e-08
GO:0065004	protein-DNA complex assembly	1.68781729974058e-08
GO:0006333	chromatin assembly or disassembly	1.92589973053561e-08
GO:0000785	chromatin	7.6750922537972e-08
GO:0006325	establishment and/or maintenance of chromatin architecture	2.39504771253207e-07
GO:0006323	DNA packaging	2.39504771253207e-07
GO:0044427	chromosomal part	3.02073060572191e-07
GO:0065003	macromolecular complex assembly	3.30771804293327e-07
GO:0005694	chromosome	4.86122415955161e-07
GO:0022607	cellular component assembly	5.29295570108079e-07
GO:0051276	chromosome organization and biogenesis	5.29295570108079e-07
GO:0006259	DNA metabolic process	3.3315282502706e-06
GO:0006996	organelle organization and biogenesis	3.31219047587105e-05
GO:0043232	intracellular non-membrane-bound organelle	9.19041659126887e-05
GO:0043228	non-membrane-bound organelle	9.19041659126887e-05
GO:0043234	protein complex	0.000111663926635138
GO:0003677	DNA binding	0.000208617178318726
GO:0032991	macromolecular complex	0.000253461686821122
GO:0044446	intracellular organelle part	0.000425046946605353
GO:0044422	organelle part	0.000425046946605353
GO:0016043	cellular component organization and biogenesis	0.000425046946605353
GO:0003676	nucleic acid binding	0.00077584897085914
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.00100471602029284
GO:0005634	nucleus	0.00314665442940148
GO:0043283	biopolymer metabolic process	0.00342409833126973
GO:0043170	macromolecule metabolic process	0.00983723022032124
GO:0044238	primary metabolic process	0.01592009323515
GO:0044237	cellular metabolic process	0.01592009323515
GO:0043231	intracellular membrane-bound organelle	0.01592009323515
GO:0043227	membrane-bound organelle	0.01592009323515
GO:0043229	intracellular organelle	0.0246068068402387
GO:0043226	organelle	0.0246068068402387
GO:0044424	intracellular part	0.0490728166954524

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
hematopoietic cell	2.49e-14	32
hematopoietic oligopotent progenitor cell	2.49e-14	32
hematopoietic stem cell	2.49e-14	32
angioblastic mesenchymal cell	2.49e-14	32
hematopoietic multipotent progenitor cell	2.49e-14	32
hematopoietic lineage restricted progenitor cell	4.21e-11	25
connective tissue cell	1.95e-10	46
mesenchymal cell	1.95e-10	46
common myeloid progenitor	3.03e-10	19
somatic cell	3.35e-10	118
motile cell	2.80e-09	54
endo-epithelial cell	3.62e-09	15
animal cell	7.39e-09	115
eukaryotic cell	7.39e-09	115
myeloid cell	3.30e-08	16
epithelial cell	1.52e-07	25
nucleate cell	3.50e-07	16
megakaryocyte-erythroid progenitor cell	5.07e-07	9

Uber Anatomy

Ontology term	p-value	n
hemolymphoid system	1.34e-12	48
immune system	1.34e-12	48
hematopoietic system	9.70e-12	45
blood island	9.70e-12	45
connective tissue	1.95e-10	46
gut epithelium	2.41e-08	55
segment of respiratory tract	4.84e-08	27
hemopoietic organ	1.12e-07	29
immune organ	1.12e-07	29
unilaminar epithelium	1.85e-07	66
mucosa	3.01e-07	15
thymus	4.76e-07	23
neck	4.76e-07	23
respiratory system epithelium	4.76e-07	23
hemolymphoid system gland	4.76e-07	23
pharyngeal epithelium	4.76e-07	23
thymic region	4.76e-07	23
pharyngeal gland	4.76e-07	23
entire pharyngeal arch endoderm	4.76e-07	23
thymus primordium	4.76e-07	23
early pharyngeal endoderm	4.76e-07	23
gland of gut	9.98e-07	24

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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