Personal tools

Coexpression cluster:C3889

From FANTOM5_SSTAR

Revision as of 15:28, 19 October 2012 by Autoedit (talk | contribs)
Jump to: navigation, search


Full id: C3889_medial_hippocampus_cerebellum_brain_parietal_olfactory_caudate



Phase1 CAGE Peaks

Hg19::chr1:160093136..160093147,+p9@ATP1A2
Hg19::chr1:160104285..160104299,+p@chr1:160104285..160104299
+
Hg19::chr1:160111383..160111418,+p@chr1:160111383..160111418
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism7.37e-80114
neural tube5.11e-7156
neural rod5.11e-7156
future spinal cord5.11e-7156
neural keel5.11e-7156
regional part of nervous system1.29e-6453
regional part of brain1.29e-6453
brain1.42e-6168
future brain1.42e-6168
central nervous system1.00e-6081
neural plate9.27e-5782
presumptive neural plate9.27e-5782
neurectoderm1.63e-5386
nervous system2.11e-5389
telencephalon1.37e-5034
brain grey matter1.84e-5034
gray matter1.84e-5034
regional part of forebrain2.13e-5041
forebrain2.13e-5041
anterior neural tube2.13e-5041
future forebrain2.13e-5041
regional part of telencephalon2.00e-4632
cerebral hemisphere2.52e-4632
structure with developmental contribution from neural crest1.88e-42132
ecto-epithelium5.47e-42104
regional part of cerebral cortex3.46e-4022
pre-chordal neural plate9.38e-3861
neocortex2.03e-3520
cerebral cortex7.57e-3525
pallium7.57e-3525
ectoderm-derived structure9.47e-31171
ectoderm9.47e-31171
presumptive ectoderm9.47e-31171
posterior neural tube7.13e-2115
chordal neural plate7.13e-2115
organ system subdivision3.60e-20223
tube7.27e-20192
basal ganglion2.20e-179
nuclear complex of neuraxis2.20e-179
aggregate regional part of brain2.20e-179
collection of basal ganglia2.20e-179
cerebral subcortex2.20e-179
neural nucleus5.33e-179
nucleus of brain5.33e-179
anatomical conduit9.09e-17240
anatomical cluster5.48e-16373
gyrus2.15e-156
segmental subdivision of hindbrain7.61e-1512
hindbrain7.61e-1512
presumptive hindbrain7.61e-1512
brainstem4.41e-146
segmental subdivision of nervous system1.47e-1313
organ part2.66e-13218
limbic system3.15e-135
telencephalic nucleus5.13e-137
occipital lobe1.84e-125
multi-tissue structure6.32e-12342
epithelium1.86e-11306
cell layer3.28e-11309
corpus striatum7.85e-114
striatum7.85e-114
ventral part of telencephalon7.85e-114
future corpus striatum7.85e-114
temporal lobe2.17e-096
organ3.62e-09503
regional part of metencephalon4.58e-099
metencephalon4.58e-099
future metencephalon4.58e-099
parietal lobe1.44e-085
caudate-putamen1.44e-083
dorsal striatum1.44e-083
frontal cortex1.48e-083
medulla oblongata3.87e-083
myelencephalon3.87e-083
future myelencephalon3.87e-083
spinal cord4.27e-083
dorsal region element4.27e-083
dorsum4.27e-083
pons1.28e-073
embryo1.32e-07592
germ layer5.19e-07560
germ layer / neural crest5.19e-07560
embryonic tissue5.19e-07560
presumptive structure5.19e-07560
germ layer / neural crest derived structure5.19e-07560
epiblast (generic)5.19e-07560
embryonic structure7.69e-07564


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.