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MCL coexpression mm9:2213

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Phase1 CAGE Peaks

 Short description
Mm9::chr17:43639666..43639688,-p1@Mep1a
Mm9::chr3:96628027..96628046,+p@chr3:96628027..96628046
+
Mm9::chr4:106406488..106406503,+p1@Fam151a
Mm9::chrX:160578379..160578427,+p2@Ace2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008237metallopeptidase activity0.00330625718654662
GO:0004238meprin A activity0.00339660886188538
GO:0008533astacin activity0.00679247332273811
GO:0008233peptidase activity0.0102100649887315
GO:0004180carboxypeptidase activity0.0261650848256211
GO:0043168anion binding0.0261650848256211
GO:0031404chloride ion binding0.0261650848256211
GO:0008270zinc ion binding0.0349106489382693
GO:0008238exopeptidase activity0.0349106489382693
GO:0004222metalloendopeptidase activity0.0349106489382693
GO:0016787hydrolase activity0.0349106489382693
GO:0046914transition metal ion binding0.0401503552812013



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
intestine1.60e-2031
gastrointestinal system5.44e-2047
mucosa3.51e-0915
intestinal mucosa1.04e-0713
anatomical wall1.04e-0713
wall of intestine1.04e-0713
gastrointestinal system mucosa1.04e-0713
kidney7.09e-0714
kidney mesenchyme7.09e-0714
upper urinary tract7.09e-0714
kidney rudiment7.09e-0714
kidney field7.09e-0714


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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