Personal tools

Coexpression cluster:C3827

From FANTOM5_SSTAR

Revision as of 16:48, 12 September 2012 by Autoedit (talk | contribs)
Jump to: navigation, search


Full id: C3827_globus_locus_caudate_cerebral_parietal_thalamus_occipital



Phase1 CAGE Peaks

Hg19::chr19:57322667..57322678,-p@chr19:57322667..57322678
-
Hg19::chr19:57324701..57324716,-p2@PEG3
Hg19::chr20:34818589..34818600,+p@chr20:34818589..34818600
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube4.11e-5357
neural rod4.11e-5357
future spinal cord4.11e-5357
neural keel4.11e-5357
adult organism3.82e-51115
regional part of forebrain3.54e-4441
forebrain3.54e-4441
future forebrain3.54e-4441
regional part of brain2.39e-4359
anterior neural tube7.87e-4342
brain1.04e-3969
future brain1.04e-3969
neurectoderm2.12e-3890
gray matter2.73e-3834
brain grey matter2.73e-3834
central nervous system2.94e-3882
neural plate1.71e-3786
presumptive neural plate1.71e-3786
telencephalon3.13e-3734
regional part of telencephalon4.75e-3633
cerebral hemisphere3.29e-3532
regional part of nervous system4.03e-3594
nervous system4.03e-3594
regional part of cerebral cortex8.38e-3022
pre-chordal neural plate5.30e-2761
neocortex7.91e-2720
cerebral cortex1.86e-2525
pallium1.86e-2525
head2.76e-20123
ectoderm4.86e-20173
presumptive ectoderm4.86e-20173
anterior region of body1.68e-19129
craniocervical region1.68e-19129
ectoderm-derived structure4.22e-19169
tube4.57e-15194
nucleus of brain1.59e-149
neural nucleus1.59e-149
basal ganglion3.08e-149
nuclear complex of neuraxis3.08e-149
aggregate regional part of brain3.08e-149
collection of basal ganglia3.08e-149
cerebral subcortex3.08e-149
anatomical conduit3.26e-14241
organ1.08e-11511
anatomical cluster1.62e-11286
telencephalic nucleus1.87e-117
posterior neural tube2.72e-1115
chordal neural plate2.72e-1115
organism subdivision4.44e-11365
gyrus5.08e-106
multi-tissue structure8.84e-10347
brainstem9.47e-108
temporal lobe1.40e-097
epithelium2.93e-09309
cell layer5.51e-09312
segmental subdivision of nervous system8.44e-0913
occipital lobe1.54e-085
parietal lobe1.57e-085
limbic system1.97e-085
diencephalon3.13e-087
future diencephalon3.13e-087
organ part6.85e-08219
embryo1.04e-07612
segmental subdivision of hindbrain1.41e-0712
hindbrain1.41e-0712
presumptive hindbrain1.41e-0712
embryonic structure2.36e-07605
developing anatomical structure2.36e-07605
corpus striatum2.85e-074
striatum2.85e-074
ventral part of telencephalon2.85e-074
future corpus striatum2.85e-074
germ layer5.76e-07604
embryonic tissue5.76e-07604
presumptive structure5.76e-07604
epiblast (generic)5.76e-07604


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.