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Coexpression cluster:C4606

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Full id: C4606_mature_choriocarcinoma_Endothelial_pancreatic_CD14_aorta_endometrial



Phase1 CAGE Peaks

Hg19::chr6:44187265..44187308,+p3@SLC29A1
Hg19::chr6:44187309..44187329,+p4@SLC29A1
Hg19::chr6:44187334..44187387,+p2@SLC29A1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
mesoderm1.24e-13448
mesoderm-derived structure1.24e-13448
presumptive mesoderm1.24e-13448
epithelial tube1.02e-12118
lateral plate mesoderm5.50e-12216
endothelium9.54e-1118
blood vessel endothelium9.54e-1118
cardiovascular system endothelium9.54e-1118
multi-cellular organism1.23e-10659
immune system5.00e-10115
embryo6.15e-10612
simple squamous epithelium1.58e-0922
anatomical group1.88e-09626
anatomical system3.39e-09625
abdominal segment of trunk5.09e-0961
abdomen5.09e-0961
embryonic structure5.93e-09605
developing anatomical structure5.93e-09605
germ layer6.84e-09604
embryonic tissue6.84e-09604
presumptive structure6.84e-09604
epiblast (generic)6.84e-09604
abdomen element1.38e-0855
abdominal segment element1.38e-0855
vessel2.28e-0869
tube2.90e-08194
squamous epithelium3.79e-0825
anatomical conduit4.38e-08241
anatomical cavity6.22e-0870
immaterial anatomical entity1.04e-07126
subdivision of trunk1.10e-07113
body cavity precursor1.54e-0763
intraembryonic coelom2.43e-0721
anatomical cluster2.76e-07286
trunk region element4.72e-07107
excretory tube5.90e-0717
mesonephric epithelium5.90e-0717
mesonephric tubule5.90e-0717
nephric duct5.90e-0717
kidney epithelium5.90e-0717
renal duct5.90e-0717
mesonephric duct5.90e-0717
pronephric duct5.90e-0717
vasculature6.98e-0779
vascular system6.98e-0779
mesonephros7.10e-0718
pronephros7.10e-0718
nephrogenic cord7.10e-0718
pronephric mesoderm7.10e-0718
rostral part of nephrogenic cord7.10e-0718
presumptive pronephric mesoderm7.10e-0718
nephron epithelium7.54e-0716
nephron7.54e-0716
uriniferous tubule7.54e-0716
metanephric mesenchyme7.54e-0716
nephrogenic mesenchyme7.54e-0716
blood vessel8.50e-0760
epithelial tube open at both ends8.50e-0760
blood vasculature8.50e-0760
vascular cord8.50e-0760
bone marrow8.57e-0780
endothelial tube8.60e-079
arterial system endothelium8.60e-079
endothelium of artery8.60e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.