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Coexpression cluster:C3205

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Full id: C3205_optic_occipital_parietal_middle_hippocampus_amygdala_temporal



Phase1 CAGE Peaks

Hg19::chr11:83818154..83818183,-p@chr11:83818154..83818183
-
Hg19::chr22:26635956..26635999,+p@chr22:26635956..26635999
+
Hg19::chr9:8501305..8501323,-p19@PTPRD


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube7.13e-6357
neural rod7.13e-6357
future spinal cord7.13e-6357
neural keel7.13e-6357
central nervous system1.05e-5282
regional part of brain6.66e-5259
regional part of nervous system5.59e-5194
nervous system5.59e-5194
regional part of forebrain9.18e-4941
forebrain9.18e-4941
future forebrain9.18e-4941
brain4.43e-4869
future brain4.43e-4869
anterior neural tube2.47e-4742
neurectoderm1.40e-4290
neural plate2.02e-4186
presumptive neural plate2.02e-4186
adult organism1.74e-38115
gray matter2.20e-3834
brain grey matter2.20e-3834
telencephalon4.99e-3834
regional part of telencephalon1.43e-3633
cerebral hemisphere6.66e-3532
pre-chordal neural plate2.23e-3261
regional part of cerebral cortex1.75e-3122
neocortex5.53e-2820
cerebral cortex5.05e-2725
pallium5.05e-2725
ectoderm9.64e-26173
presumptive ectoderm9.64e-26173
head5.69e-25123
ectoderm-derived structure1.49e-24169
anterior region of body2.59e-24129
craniocervical region2.59e-24129
posterior neural tube5.39e-1615
chordal neural plate5.39e-1615
tube2.86e-13194
segmental subdivision of nervous system2.95e-1313
basal ganglion8.06e-139
nuclear complex of neuraxis8.06e-139
aggregate regional part of brain8.06e-139
collection of basal ganglia8.06e-139
cerebral subcortex8.06e-139
nucleus of brain8.85e-139
neural nucleus8.85e-139
diencephalon3.31e-127
future diencephalon3.31e-127
segmental subdivision of hindbrain1.33e-1112
hindbrain1.33e-1112
presumptive hindbrain1.33e-1112
temporal lobe2.10e-117
brainstem3.64e-118
gyrus6.48e-116
epithelium3.46e-10309
limbic system4.72e-105
cell layer6.44e-10312
telencephalic nucleus1.86e-097
parietal lobe2.58e-095
anatomical conduit8.27e-09241
organ part5.23e-08219
organism subdivision8.40e-08365
gland of diencephalon1.71e-074
neuroendocrine gland1.71e-074
regional part of metencephalon2.85e-079
metencephalon2.85e-079
future metencephalon2.85e-079
anatomical cluster5.60e-07286
middle temporal gyrus6.96e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.