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Coexpression cluster:C2806

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Full id: C2806_occipital_parietal_duodenum_temporal_nonsmall_small_merkel



Phase1 CAGE Peaks

Hg19::chr5:140227945..140227976,+p1@PCDHA9
Hg19::chr6:124125170..124125204,+p3@NKAIN2
Hg19::chr6:124125310..124125362,+p1@NKAIN2
Hg19::chr6:124125374..124125386,+p9@NKAIN2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube9.46e-6756
neural rod9.46e-6756
future spinal cord9.46e-6756
neural keel9.46e-6756
central nervous system7.23e-6281
regional part of nervous system1.17e-6153
regional part of brain1.17e-6153
nervous system2.59e-6089
neurectoderm6.91e-5386
brain7.38e-5168
future brain7.38e-5168
regional part of forebrain8.59e-4941
forebrain8.59e-4941
anterior neural tube8.59e-4941
future forebrain8.59e-4941
neural plate3.01e-4882
presumptive neural plate3.01e-4882
adult organism7.84e-48114
telencephalon1.55e-4434
brain grey matter3.58e-4434
gray matter3.58e-4434
cerebral hemisphere2.34e-4132
regional part of telencephalon2.52e-4132
ecto-epithelium2.86e-39104
ectoderm-derived structure4.17e-38171
ectoderm4.17e-38171
presumptive ectoderm4.17e-38171
pre-chordal neural plate1.09e-3461
regional part of cerebral cortex1.37e-3322
cerebral cortex2.18e-3125
pallium2.18e-3125
neocortex1.02e-3020
structure with developmental contribution from neural crest2.26e-29132
organ system subdivision9.91e-28223
posterior neural tube2.70e-1815
chordal neural plate2.70e-1815
segmental subdivision of nervous system3.27e-1513
neural nucleus4.07e-149
nucleus of brain4.07e-149
basal ganglion4.13e-149
nuclear complex of neuraxis4.13e-149
aggregate regional part of brain4.13e-149
collection of basal ganglia4.13e-149
cerebral subcortex4.13e-149
tube4.83e-14192
segmental subdivision of hindbrain1.40e-1312
hindbrain1.40e-1312
presumptive hindbrain1.40e-1312
anatomical cluster1.45e-12373
telencephalic nucleus2.27e-117
gyrus8.17e-116
anatomical conduit9.20e-11240
brainstem1.27e-106
organ part2.19e-10218
parietal lobe1.74e-095
occipital lobe2.07e-095
regional part of metencephalon3.41e-099
metencephalon3.41e-099
future metencephalon3.41e-099
temporal lobe4.20e-096
limbic system1.20e-085
epithelium8.09e-08306
cell layer1.38e-07309
multi-tissue structure2.21e-07342
corpus striatum4.11e-074
striatum4.11e-074
ventral part of telencephalon4.11e-074
future corpus striatum4.11e-074


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.12.92335
MA0004.10.71247
MA0006.10.532262
MA0007.10.6918
MA0009.11.20602
MA0014.10.244769
MA0017.10.577281
MA0019.10.873355
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.10.25531
MA0050.10.69864
MA0051.10.820063
MA0052.11.12718
MA0055.16.61141
MA0056.10
MA0057.10.248209
MA0058.11.47358
MA0059.11.47051
MA0060.11.01899
MA0061.10.360128
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.10.313194
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.10.00636811
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.10.536981
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.11.6149
MA0093.11.32557
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.10.539569
MA0103.10.521546
MA0105.10.232357
MA0106.10.869173
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.10.886811
MA0114.10.447443
MA0115.11.45393
MA0116.10.457606
MA0117.11.24497
MA0119.10.586221
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.344952
MA0140.11.83481
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.10.569905
MA0146.10.061409
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.21.83323
MA0039.20.0247757
MA0138.20.928035
MA0002.20.379056
MA0137.20.558189
MA0104.21.01696
MA0047.20.856092
MA0112.20.551048
MA0065.20.577908
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.10.229241
MA0155.10.533581
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.10.462502
MA0160.10.756582
MA0161.10
MA0162.13.50007
MA0163.11.37853
MA0164.10.90014
MA0080.20.535868
MA0018.20.870662
MA0099.20.7872
MA0079.20.0626799
MA0102.21.75932
MA0258.11.07498
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.