MCL coexpression mm9:2433

Phase1 CAGE Peaks

	Short description
Mm9::chr5:93326982..93327000,+	p6@Shroom3
Mm9::chr5:93327007..93327078,+	p3@Shroom3
Mm9::chr5:93327079..93327101,+	p5@Shroom3
Mm9::chr9:107507626..107507662,-	p2@Sema3b

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0002065	columnar/cuboidal epithelial cell differentiation	0.00876544222422034
GO:0002066	columnar/cuboidal epithelial cell development	0.00876544222422034
GO:0002064	epithelial cell development	0.0204498970139181
GO:0007399	nervous system development	0.0228906919482546
GO:0030855	epithelial cell differentiation	0.0306781855020501
GO:0001843	neural tube closure	0.0306781855020501
GO:0014020	primary neural tube formation	0.0306781855020501
GO:0022603	regulation of anatomical structure morphogenesis	0.0306781855020501
GO:0008360	regulation of cell shape	0.0306781855020501
GO:0022604	regulation of cell morphogenesis	0.0306781855020501
GO:0016324	apical plasma membrane	0.0306781855020501
GO:0001841	neural tube formation	0.0306781855020501
GO:0001839	neural plate morphogenesis	0.0306781855020501
GO:0001840	neural plate development	0.0306781855020501
GO:0001838	embryonic epithelial tube formation	0.0306781855020501
GO:0005912	adherens junction	0.0306781855020501
GO:0021915	neural tube development	0.0306781855020501
GO:0016331	morphogenesis of embryonic epithelium	0.0306781855020501
GO:0048731	system development	0.0306781855020501
GO:0045177	apical part of cell	0.0306781855020501
GO:0048869	cellular developmental process	0.0306781855020501
GO:0030154	cell differentiation	0.0306781855020501
GO:0043296	apical junction complex	0.032791165650253
GO:0016327	apicolateral plasma membrane	0.032791165650253
GO:0048856	anatomical structure development	0.0348025444443735
GO:0002009	morphogenesis of an epithelium	0.0403686812337117
GO:0007275	multicellular organismal development	0.0403686812337117
GO:0035239	tube morphogenesis	0.0448085718115091
GO:0005911	intercellular junction	0.0448085718115091
GO:0030036	actin cytoskeleton organization and biogenesis	0.0448085718115091
GO:0030029	actin filament-based process	0.046446441539182

Relative expression of the co-expression cluster over median <br>Analyst:

---

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

---

Uber Anatomy

Ontology term	p-value	n
gastrointestinal system	1.26e-21	47
intestine	2.99e-19	31
mucosa	2.26e-09	15
intestinal mucosa	1.45e-08	13
anatomical wall	1.45e-08	13
wall of intestine	1.45e-08	13
gastrointestinal system mucosa	1.45e-08	13
multi-cellular organism	5.67e-08	333
organ component layer	1.56e-07	24
embryo	3.31e-07	320

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}