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MCL coexpression mm9:461

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:51506964..51506968,-p@chr11:51506964..51506968
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Mm9::chr14:56373291..56373319,-p@chr14:56373291..56373319
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Mm9::chr2:90758551..90758599,-p4@Ptpmt1
Mm9::chr3:88949993..88949997,+p@chr3:88949993..88949997
+
Mm9::chr4:49554145..49554167,-p@chr4:49554145..49554167
-
Mm9::chr9:46037034..46037063,+p3@Apoa1
Mm9::chr9:46037245..46037274,+p@chr9:46037245..46037274
+
Mm9::chr9:46037284..46037329,+p@chr9:46037284..46037329
+
Mm9::chr9:46037905..46037991,+p@chr9:46037905..46037991
+
Mm9::chr9:46037992..46038069,+p@chr9:46037992..46038069
+
Mm9::chr9:46038084..46038105,+p@chr9:46038084..46038105
+
Mm9::chr9:46038124..46038147,+p@chr9:46038124..46038147
+
Mm9::chr9:46038168..46038182,+p@chr9:46038168..46038182
+
Mm9::chr9:46038285..46038313,+p@chr9:46038285..46038313
+
Mm9::chr9:46038315..46038326,+p@chr9:46038315..46038326
+
Mm9::chr9:46038334..46038346,+p@chr9:46038334..46038346
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006644phospholipid metabolic process0.0100646322602822
GO:0006643membrane lipid metabolic process0.0100646322602822
GO:0008035high-density lipoprotein binding0.0100646322602822
GO:0043534blood vessel endothelial cell migration0.0100646322602822
GO:0006066alcohol metabolic process0.0100646322602822
GO:0030300regulation of cholesterol absorption0.0100646322602822
GO:0033344cholesterol efflux0.0100646322602822
GO:0030299cholesterol absorption0.0100646322602822
GO:0051346negative regulation of hydrolase activity0.0100646322602822
GO:0044241lipid digestion0.0100646322602822
GO:0004332fructose-bisphosphate aldolase activity0.0100646322602822
GO:0004439phosphoinositide 5-phosphatase activity0.0100646322602822
GO:0017127cholesterol transporter activity0.0104993479606997
GO:0043542endothelial cell migration0.0104993479606997
GO:0016832aldehyde-lyase activity0.0104993479606997
GO:0015248sterol transporter activity0.0104993479606997
GO:0001935endothelial cell proliferation0.0104993479606997
GO:0050892intestinal absorption0.0104993479606997
GO:0008211glucocorticoid metabolic process0.0104993479606997
GO:0030325adrenal gland development0.0104993479606997
GO:0019915sequestering of lipid0.0104993479606997
GO:0046488phosphatidylinositol metabolic process0.0104993479606997
GO:0042577lipid phosphatase activity0.0104993479606997
GO:0022600digestive system process0.0125187001789079
GO:0008034lipoprotein binding0.0125187001789079
GO:0044255cellular lipid metabolic process0.0125187001789079
GO:0030301cholesterol transport0.0125187001789079
GO:0015918sterol transport0.012933152358935
GO:0006629lipid metabolic process0.0151075883712702
GO:0006695cholesterol biosynthetic process0.0176972577212691
GO:0016126sterol biosynthetic process0.0225670200839581
GO:0004437inositol or phosphatidylinositol phosphatase activity0.0226144161912928
GO:0006793phosphorus metabolic process0.0231003898986493
GO:0006796phosphate metabolic process0.0231003898986493
GO:0008138protein tyrosine/serine/threonine phosphatase activity0.0241154328663319
GO:0016830carbon-carbon lyase activity0.0253987668275815
GO:0007586digestion0.0253987668275815
GO:0030384phosphoinositide metabolic process0.0253987668275815
GO:0006096glycolysis0.0253987668275815
GO:0005319lipid transporter activity0.0253987668275815
GO:0042158lipoprotein biosynthetic process0.0253987668275815
GO:0043086negative regulation of catalytic activity0.0253987668275815
GO:0035270endocrine system development0.0253987668275815
GO:0033238regulation of amine metabolic process0.0253987668275815
GO:0001932regulation of protein amino acid phosphorylation0.0253987668275815
GO:0006521regulation of amino acid metabolic process0.0253987668275815
GO:0006007glucose catabolic process0.0253987668275815
GO:0046365monosaccharide catabolic process0.0253987668275815
GO:0019320hexose catabolic process0.0253987668275815
GO:0042325regulation of phosphorylation0.0253987668275815
GO:0051174regulation of phosphorus metabolic process0.0253987668275815
GO:0046164alcohol catabolic process0.0253987668275815
GO:0019220regulation of phosphate metabolic process0.0253987668275815
GO:0042157lipoprotein metabolic process0.0253987668275815
GO:0006650glycerophospholipid metabolic process0.0253987668275815
GO:0008203cholesterol metabolic process0.0275166999907174
GO:0044275cellular carbohydrate catabolic process0.0278757035020892
GO:0006694steroid biosynthetic process0.0286356062966939
GO:0016125sterol metabolic process0.0287214385786459
GO:0016052carbohydrate catabolic process0.0287214385786459
GO:0006869lipid transport0.0287214385786459
GO:0048732gland development0.0287214385786459
GO:0042445hormone metabolic process0.0306269909533715
GO:0043687post-translational protein modification0.0306269909533715
GO:0004725protein tyrosine phosphatase activity0.0318174451233092
GO:0051347positive regulation of transferase activity0.0324231184672487
GO:0006006glucose metabolic process0.0347948497498764
GO:0006470protein amino acid dephosphorylation0.0373990372565175
GO:0006464protein modification process0.0373990372565175
GO:0051336regulation of hydrolase activity0.0373990372565175
GO:0043412biopolymer modification0.0391151911267399
GO:0016311dephosphorylation0.0393429465131948
GO:0019318hexose metabolic process0.0426022080885103
GO:0043085positive regulation of catalytic activity0.0426022080885103
GO:0005996monosaccharide metabolic process0.0426022080885103
GO:0051338regulation of transferase activity0.0426022080885103
GO:0008202steroid metabolic process0.0435943265602065
GO:0004721phosphoprotein phosphatase activity0.0442552835622009
GO:0016829lyase activity0.0456561661233562
GO:0043170macromolecule metabolic process0.0456561661233562



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
liver2.91e-1722
epithelial sac2.91e-1722
digestive gland2.91e-1722
epithelium of foregut-midgut junction2.91e-1722
anatomical boundary2.91e-1722
hepatobiliary system2.91e-1722
foregut-midgut junction2.91e-1722
hepatic diverticulum2.91e-1722
liver primordium2.91e-1722
septum transversum2.91e-1722
liver bud2.91e-1722
intestine1.16e-1631
digestive tract diverticulum3.80e-1623
sac3.80e-1623
exocrine gland3.39e-1425
exocrine system3.39e-1425
gastrointestinal system9.24e-1447
endoderm-derived structure1.10e-12118
endoderm1.10e-12118
presumptive endoderm1.10e-12118
digestive system5.80e-12116
digestive tract5.80e-12116
primitive gut5.80e-12116
mucosa5.73e-1115
subdivision of digestive tract1.03e-10114
intestinal mucosa4.85e-0913
anatomical wall4.85e-0913
wall of intestine4.85e-0913
gastrointestinal system mucosa4.85e-0913
organ component layer5.34e-0824
trunk mesenchyme5.60e-0845
gut epithelium9.18e-0855
abdomen element9.48e-0849
abdominal segment element9.48e-0849
abdominal segment of trunk9.48e-0849
abdomen9.48e-0849


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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