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Coexpression cluster:C429

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Full id: C429_anaplastic_Mast_clear_Neutrophils_squamous_Eosinophils_oral



Phase1 CAGE Peaks

Hg19::chr10:28367018..28367027,+p@chr10:28367018..28367027
+
Hg19::chr10:28367095..28367106,+p@chr10:28367095..28367106
+
Hg19::chr10:28367218..28367230,+p@chr10:28367218..28367230
+
Hg19::chr10:28367236..28367266,+p@chr10:28367236..28367266
+
Hg19::chr10:28367270..28367278,+p@chr10:28367270..28367278
+
Hg19::chr12:127256858..127256871,-p1@ENST00000542248
Hg19::chr16:56648492..56648498,-p@chr16:56648492..56648498
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Hg19::chr16:56648503..56648510,-p@chr16:56648503..56648510
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Hg19::chr16:56648532..56648539,-p@chr16:56648532..56648539
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Hg19::chr17:31099607..31099657,-p@chr17:31099607..31099657
-
Hg19::chr20:32951056..32951067,+p2@ITCH
Hg19::chr20:32951070..32951122,+p1@ITCH
Hg19::chr21:19858196..19858204,-p2@TMPRSS15
Hg19::chr2:17603261..17603273,-p@chr2:17603261..17603273
-
Hg19::chr2:26915639..26915654,+p3@KCNK3
Hg19::chr4:20253897..20253905,+p@chr4:20253897..20253905
+
Hg19::chr8:33330595..33330689,-p1@FUT10
Hg19::chr8:33370607..33370676,-p1@TTI2
Hg19::chr8:33744758..33744766,-p@chr8:33744758..33744766
-
Hg19::chr8:33744817..33744827,-p@chr8:33744817..33744827
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Hg19::chr8:55467072..55467091,+p1@ENST00000518787
Hg19::chr9:106503385..106503391,-p@chr9:106503385..106503391
-
Hg19::chr9:114714967..114714986,-p@chr9:114714967..114714986
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0022414reproductive process0.00996864124799369
GO:0009611response to wounding0.00996864124799369
GO:0046920alpha(1,3)-fucosyltransferase activity0.00996864124799369
GO:0044265cellular macromolecule catabolic process0.00996864124799369
GO:0019317fucose catabolic process0.00996864124799369
GO:0042355L-fucose catabolic process0.00996864124799369
GO:0044409entry into host0.00996864124799369
GO:0030260entry into host cell0.00996864124799369
GO:0042354L-fucose metabolic process0.00996864124799369
GO:0019059initiation of viral infection0.00996864124799369
GO:0052192movement in environment of other organism during symbiotic interaction0.00996864124799369
GO:0046718entry of virus into host cell0.00996864124799369
GO:0052126movement in host environment0.00996864124799369
GO:0051828entry into other organism during symbiotic interaction0.00996864124799369
GO:0051806entry into cell of other organism during symbiotic interaction0.00996864124799369
GO:0009057macromolecule catabolic process0.00996864124799369
GO:0009605response to external stimulus0.00996864124799369
GO:0006004fucose metabolic process0.0121373491035594
GO:0008417fucosyltransferase activity0.0137966119781209
GO:0044248cellular catabolic process0.0137966119781209
GO:0051701interaction with host0.0152552373701995
GO:0009056catabolic process0.0180874098061372
GO:0044403symbiosis, encompassing mutualism through parasitism0.0194100405888146
GO:0044419interspecies interaction between organisms0.0194100405888146
GO:0006950response to stress0.0249860686985649
GO:0019058viral infectious cycle0.0279804151465854
GO:0022415viral reproductive process0.0301318038301384
GO:0009566fertilization0.0301318038301384



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
epithelial cell of cervix1.44e-092
bone matrix secreting cell2.02e-092
osteocyte2.02e-092
osteoclast2.02e-092


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
BATF#1053844.236139442139760.01344575848030930.0475006450605496
ESR1#209956.688826803511840.0007460539146123150.00587477379086146



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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