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Coexpression cluster:C3161

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Full id: C3161_skeletal_spinal_hippocampus_medulla_teratocarcinoma_skin_amygdala



Phase1 CAGE Peaks

Hg19::chr11:57003063..57003075,-p@chr11:57003063..57003075
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Hg19::chr11:57003843..57003857,-p@chr11:57003843..57003857
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Hg19::chr11:57003864..57003887,-p@chr11:57003864..57003887
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.58e-45114
neural tube3.27e-4356
neural rod3.27e-4356
future spinal cord3.27e-4356
neural keel3.27e-4356
regional part of nervous system9.89e-3753
regional part of brain9.89e-3753
central nervous system1.48e-3481
neural plate1.14e-3282
presumptive neural plate1.14e-3282
brain grey matter3.26e-3134
gray matter3.26e-3134
telencephalon8.59e-3134
neurectoderm1.06e-3086
nervous system3.70e-3089
brain1.97e-2868
future brain1.97e-2868
regional part of forebrain2.81e-2741
forebrain2.81e-2741
anterior neural tube2.81e-2741
future forebrain2.81e-2741
regional part of telencephalon4.27e-2732
cerebral hemisphere1.04e-2632
ecto-epithelium1.84e-25104
structure with developmental contribution from neural crest1.73e-24132
organ system subdivision1.01e-19223
regional part of cerebral cortex2.58e-1922
neural nucleus2.81e-189
nucleus of brain2.81e-189
pre-chordal neural plate4.92e-1861
posterior neural tube2.23e-1715
chordal neural plate2.23e-1715
ectoderm-derived structure3.17e-17171
ectoderm3.17e-17171
presumptive ectoderm3.17e-17171
cerebral cortex1.12e-1625
pallium1.12e-1625
neocortex3.18e-1520
basal ganglion4.17e-149
nuclear complex of neuraxis4.17e-149
aggregate regional part of brain4.17e-149
collection of basal ganglia4.17e-149
cerebral subcortex4.17e-149
telencephalic nucleus1.78e-137
tube1.22e-12192
anatomical cluster2.23e-12373
organ part4.08e-12218
brainstem4.29e-126
corpus striatum8.34e-114
striatum8.34e-114
ventral part of telencephalon8.34e-114
future corpus striatum8.34e-114
gyrus1.17e-106
segmental subdivision of hindbrain1.34e-1012
hindbrain1.34e-1012
presumptive hindbrain1.34e-1012
anatomical conduit3.98e-10240
spinal cord5.87e-103
dorsal region element5.87e-103
dorsum5.87e-103
medulla oblongata1.07e-093
myelencephalon1.07e-093
future myelencephalon1.07e-093
segmental subdivision of nervous system1.08e-0913
limbic system2.80e-095
multi-tissue structure3.28e-09342
small intestine8.35e-094
caudate-putamen9.04e-093
dorsal striatum9.04e-093
epithelium5.04e-08306
cell layer7.70e-08309
Ammon's horn5.96e-072
lobe parts of cerebral cortex5.96e-072
hippocampal formation5.96e-072
limbic lobe5.96e-072


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.