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MCL coexpression mm9:1110

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Phase1 CAGE Peaks

 Short description
Mm9::chr13:20183389..20183396,-p@chr13:20183389..20183396
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Mm9::chr3:131153711..131153732,-p@chr3:131153711..131153732
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Mm9::chr3:65332356..65332376,+p1@Tiparp
Mm9::chr3:95462660..95462671,+p2@Mcl1
Mm9::chr6:66985288..66985293,-p@chr6:66985288..66985293
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Mm9::chr6:66987372..66987388,-p2@Gadd45a
Mm9::chr6:66987393..66987411,-p1@Gadd45a


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007098centrosome cycle0.0384362570726464
GO:0051297centrosome organization and biogenesis0.0384362570726464
GO:0031023microtubule organizing center organization and biogenesis0.0384362570726464
GO:0003950NAD+ ADP-ribosyltransferase activity0.0384362570726464
GO:0006471protein amino acid ADP-ribosylation0.0409896878723836



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
epithelial cell2.23e-0725

Uber Anatomy
Ontology termp-valuen
organ component layer1.92e-0924
musculoskeletal system8.87e-0932
mucosa5.23e-0815
intestine1.07e-0731
gastrointestinal system3.79e-0747
intestinal mucosa5.08e-0713
anatomical wall5.08e-0713
wall of intestine5.08e-0713
gastrointestinal system mucosa5.08e-0713


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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