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MCL coexpression mm9:1949: Difference between revisions

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{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=
|ontology_enrichment_celltype=CL:0000117!8.99e-11!23;CL:0000337!8.99e-11!23;CL:0002614!3.89e-10!3;CL:0002610!6.63e-10!3;CL:0000540!6.30e-07!33;CL:0000047!6.30e-07!33;CL:0000031!6.30e-07!33;CL:0000404!6.30e-07!33
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000073!4.05e-38!54;UBERON:0001049!1.52e-33!52;UBERON:0005068!1.52e-33!52;UBERON:0006241!1.52e-33!52;UBERON:0007135!1.52e-33!52;UBERON:0001017!4.99e-29!73;UBERON:0002346!2.32e-28!64;UBERON:0003075!2.32e-28!64;UBERON:0007284!2.32e-28!64;UBERON:0001016!4.23e-28!75;UBERON:0002616!9.95e-25!46;UBERON:0002020!1.35e-24!34;UBERON:0010371!3.61e-24!73;UBERON:0000955!4.23e-24!47;UBERON:0006238!4.23e-24!47;UBERON:0004121!1.37e-22!95;UBERON:0000924!1.37e-22!95;UBERON:0006601!1.37e-22!95;UBERON:0002021!4.86e-20!10;UBERON:0000411!4.86e-20!10;UBERON:0001950!4.86e-20!10;UBERON:0003080!1.72e-18!40;UBERON:0003528!4.99e-18!29;UBERON:0002791!4.99e-18!29;UBERON:0001893!4.99e-18!29;UBERON:0010314!5.29e-18!92;UBERON:0003076!3.01e-17!12;UBERON:0003057!3.01e-17!12;UBERON:0002780!8.53e-17!39;UBERON:0001890!8.53e-17!39;UBERON:0006240!8.53e-17!39;UBERON:0003056!4.13e-16!49;UBERON:0002619!9.01e-14!17;UBERON:0000956!3.97e-13!21;UBERON:0001869!3.97e-13!21;UBERON:0000203!3.97e-13!21;UBERON:0002950!1.49e-12!4;UBERON:0001891!1.49e-12!4;UBERON:0009616!1.49e-12!4;UBERON:0010286!1.49e-12!4;UBERON:0000025!2.90e-12!114;UBERON:0004111!4.34e-11!122;UBERON:0002240!5.82e-11!6;UBERON:0005174!5.82e-11!6;UBERON:0001137!5.82e-11!6;UBERON:0002038!3.89e-10!3;UBERON:0009663!3.89e-10!3;UBERON:0009661!3.89e-10!3;UBERON:0000125!3.89e-10!3;UBERON:0002308!3.89e-10!3;UBERON:0004684!6.63e-10!3;UBERON:0002275!6.63e-10!3;UBERON:0001948!1.89e-08!5;UBERON:0002315!1.89e-08!5;UBERON:0004733!6.14e-08!6;UBERON:0004732!6.14e-08!6;UBERON:0002028!6.14e-08!6;UBERON:0007277!6.14e-08!6;UBERON:0000064!7.71e-08!99;UBERON:0011216!3.57e-07!194;UBERON:0001896!5.49e-07!2;UBERON:0002298!5.49e-07!2;UBERON:0005290!5.49e-07!2;UBERON:0010096!5.49e-07!2;UBERON:0000483!8.64e-07!174
|tfbs_overrepresentation_for_novel_motifs=0.641384,0.128156,0.612053,0.688265,0.483253,0.704257,0.803568,0.96814,0.381467,0.162942,0.755749,0.790506,0.37041,0.81685,1.2551,0,1.02248,0.473993,0.352304,0.24402,0.570433,0.57409,0.815872,1.20979,0.620553,0.846564,0.342316,0.727368,0.535752,0.290745,0.711848,1.12823,2.06579,0.318879,0.503207,16.7837,0.460474,0.786577,0.434783,5.96135,0.478558,0.717547,0.185353,1.26006,0.0986756,0.675898,0.938241,0.744678,0.162985,0.539131,1.0041,0.875451,0.282443,1.2746,1.29252,0.82458,0.549352,0.776619,0.331485,0.822375,1.10737,0.885556,0.39557,0.992216,0.8366,1.03484,1.43193,1.78579,1.1025,1.63712,0.590754,0.377213,0.205546,1.32691,0.323563,0.834514,0.318792,0.926147,1.08947,0.575233,0.37865,1.04072,0.884013,0.362446,1.20828,0.11855,0.129654,0.290918,0.943446,1.94914,1.50286,1.21342,1.14153,0.490141,0.430015,0.409166,0.367176,1.14445,0.938512,0.264911,0.460566,1.12793,1.25667,1.00472,1.00361,0.717061,1.06633,1.75347,0.580757,0.57247,0.633483,1.25851,0.576517,0.7614,1.51002,0.476467,0.143825,0.692434,1.02384,0.456123,1.33244,0.970073,0.848526,0.925183,1.56496,1.09333,0.812403,1.13449,1.43038,0.493609,1.23918,0.680176,3.09564,0.839311,1.53196,0.195549,0.650785,0.719099,1.482,2.31884,1.91709,1.43673,0.861473,1.1391,0.996781,1.70745,0.941555,2.27909,0.653418,0.485304,0.293812,0.184289,1.27621,0.416214,0.838313,1.35996,0.87653,0.516549,0.63863,0.650472,1.49167,1.20739,1.09379,1.52606,0.993294,0.830321,0.459159,0.788782,0.0824127
|tfbs_overrepresentation_jaspar=MA0003.1;0.0356887,MA0004.1;0.6888,MA0006.1;0.497533,MA0007.1;0.672186,MA0009.1;1.15569,MA0014.1;0.0809287,MA0017.1;0.528196,MA0019.1;0.964875,MA0024.1;1.11019,MA0025.1;1.39562,MA0027.1;2.81824,MA0028.1;0.509589,MA0029.1;1.08753,MA0030.1;1.09438,MA0031.1;1.05719,MA0038.1;0.846479,MA0040.1;1.16866,MA0041.1;0.604221,MA0042.1;0.589368,MA0043.1;1.25564,MA0046.1;1.1929,MA0048.1;0.266382,MA0050.1;0.731539,MA0051.1;0.856094,MA0052.1;1.17701,MA0055.1;0.790894,MA0056.1;0,MA0057.1;1.29714,MA0058.1;0.581673,MA0059.1;0.59559,MA0060.1;0.403071,MA0061.1;0.438628,MA0063.1;0,MA0066.1;0.834648,MA0067.1;1.50873,MA0068.1;0.256913,MA0069.1;1.17737,MA0070.1;1.16732,MA0071.1;0.73062,MA0072.1;1.15853,MA0073.1;0.00221226,MA0074.1;0.795862,MA0076.1;0.550092,MA0077.1;1.13603,MA0078.1;0.891476,MA0081.1;1.5065,MA0083.1;1.25482,MA0084.1;1.84013,MA0087.1;1.21037,MA0088.1;0.201215,MA0089.1;0,MA0090.1;0.650768,MA0091.1;0.703314,MA0092.1;0.651119,MA0093.1;0.519148,MA0095.1;0,MA0098.1;0,MA0100.1;0.783305,MA0101.1;0.605676,MA0103.1;0.540576,MA0105.1;0.313353,MA0106.1;0.899777,MA0107.1;0.533522,MA0108.2;0.989014,MA0109.1;0,MA0111.1;0.666525,MA0113.1;0.869608,MA0114.1;0.43587,MA0115.1;1.25852,MA0116.1;0.497293,MA0117.1;1.22527,MA0119.1;0.606338,MA0122.1;1.24573,MA0124.1;1.45461,MA0125.1;1.37907,MA0130.1;0,MA0131.1;0.960068,MA0132.1;0,MA0133.1;0,MA0135.1;1.29308,MA0136.1;0.817395,MA0139.1;0.365453,MA0140.1;0.78318,MA0141.1;0.563066,MA0142.1;1.04199,MA0143.1;0.887119,MA0144.1;0.439506,MA0145.1;0.21199,MA0146.1;0.0944145,MA0147.1;0.453952,MA0148.1;0.706718,MA0149.1;0.611881,MA0062.2;0.319836,MA0035.2;0.788288,MA0039.2;0.0220513,MA0138.2;0.951653,MA0002.2;0.965577,MA0137.2;0.559766,MA0104.2;0.386166,MA0047.2;0.845655,MA0112.2;0.211985,MA0065.2;0.609584,MA0150.1;0.67206,MA0151.1;0,MA0152.1;0.84577,MA0153.1;1.31015,MA0154.1;0.728853,MA0155.1;0.230016,MA0156.1;0.549102,MA0157.1;1.0083,MA0158.1;0,MA0159.1;0.465802,MA0160.1;0.71003,MA0161.1;0,MA0162.1;0.10667,MA0163.1;0.0996272,MA0164.1;0.817786,MA0080.2;0.534538,MA0018.2;0.828253,MA0099.2;0.944966,MA0079.2;2.24437,MA0102.2;1.8929,MA0258.1;0.419871,MA0259.1;0.441366,MA0442.1;0
}}

Latest revision as of 17:45, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:115854376..115854386,+p11@Itgb4
Mm9::chr9:120089048..120089059,+p@chr9:120089048..120089059
+
Mm9::chr9:120089132..120089144,+p@chr9:120089132..120089144
+
Mm9::chr9:120089380..120089395,+p@chr9:120089380..120089395
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

no results for this coexpression

Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)8.99e-1123
neuroblast (sensu Vertebrata)8.99e-1123
neuron of the substantia nigra3.89e-103
raphe nuclei neuron6.63e-103
neuron6.30e-0733
neuronal stem cell6.30e-0733
neuroblast6.30e-0733
electrically signaling cell6.30e-0733

Uber Anatomy
Ontology termp-valuen
regional part of nervous system4.05e-3854
neural tube1.52e-3352
neural rod1.52e-3352
future spinal cord1.52e-3352
neural keel1.52e-3352
central nervous system4.99e-2973
neurectoderm2.32e-2864
neural plate2.32e-2864
presumptive neural plate2.32e-2864
nervous system4.23e-2875
regional part of brain9.95e-2546
gray matter1.35e-2434
ecto-epithelium3.61e-2473
brain4.23e-2447
future brain4.23e-2447
ectoderm-derived structure1.37e-2295
ectoderm1.37e-2295
presumptive ectoderm1.37e-2295
occipital lobe4.86e-2010
visual cortex4.86e-2010
neocortex4.86e-2010
anterior neural tube1.72e-1840
brain grey matter4.99e-1829
regional part of telencephalon4.99e-1829
telencephalon4.99e-1829
structure with developmental contribution from neural crest5.29e-1892
posterior neural tube3.01e-1712
chordal neural plate3.01e-1712
regional part of forebrain8.53e-1739
forebrain8.53e-1739
future forebrain8.53e-1739
pre-chordal neural plate4.13e-1649
regional part of cerebral cortex9.01e-1417
cerebral cortex3.97e-1321
cerebral hemisphere3.97e-1321
pallium3.97e-1321
regional part of midbrain1.49e-124
midbrain1.49e-124
presumptive midbrain1.49e-124
midbrain neural tube1.49e-124
tube2.90e-12114
anatomical conduit4.34e-11122
spinal cord5.82e-116
dorsal region element5.82e-116
dorsum5.82e-116
substantia nigra3.89e-103
telencephalic nucleus3.89e-103
midbrain nucleus3.89e-103
neural nucleus3.89e-103
nucleus of brain3.89e-103
raphe nuclei6.63e-103
reticular formation6.63e-103
regional part of spinal cord1.89e-085
gray matter of spinal cord1.89e-085
segmental subdivision of hindbrain6.14e-086
segmental subdivision of nervous system6.14e-086
hindbrain6.14e-086
presumptive hindbrain6.14e-086
organ part7.71e-0899
organ system subdivision3.57e-07194
medulla oblongata5.49e-072
brainstem5.49e-072
myelencephalon5.49e-072
future myelencephalon5.49e-072
epithelium8.64e-07174


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0356887
MA0004.10.6888
MA0006.10.497533
MA0007.10.672186
MA0009.11.15569
MA0014.10.0809287
MA0017.10.528196
MA0019.10.964875
MA0024.11.11019
MA0025.11.39562
MA0027.12.81824
MA0028.10.509589
MA0029.11.08753
MA0030.11.09438
MA0031.11.05719
MA0038.10.846479
MA0040.11.16866
MA0041.10.604221
MA0042.10.589368
MA0043.11.25564
MA0046.11.1929
MA0048.10.266382
MA0050.10.731539
MA0051.10.856094
MA0052.11.17701
MA0055.10.790894
MA0056.10
MA0057.11.29714
MA0058.10.581673
MA0059.10.59559
MA0060.10.403071
MA0061.10.438628
MA0063.10
MA0066.10.834648
MA0067.11.50873
MA0068.10.256913
MA0069.11.17737
MA0070.11.16732
MA0071.10.73062
MA0072.11.15853
MA0073.10.00221226
MA0074.10.795862
MA0076.10.550092
MA0077.11.13603
MA0078.10.891476
MA0081.11.5065
MA0083.11.25482
MA0084.11.84013
MA0087.11.21037
MA0088.10.201215
MA0089.10
MA0090.10.650768
MA0091.10.703314
MA0092.10.651119
MA0093.10.519148
MA0095.10
MA0098.10
MA0100.10.783305
MA0101.10.605676
MA0103.10.540576
MA0105.10.313353
MA0106.10.899777
MA0107.10.533522
MA0108.20.989014
MA0109.10
MA0111.10.666525
MA0113.10.869608
MA0114.10.43587
MA0115.11.25852
MA0116.10.497293
MA0117.11.22527
MA0119.10.606338
MA0122.11.24573
MA0124.11.45461
MA0125.11.37907
MA0130.10
MA0131.10.960068
MA0132.10
MA0133.10
MA0135.11.29308
MA0136.10.817395
MA0139.10.365453
MA0140.10.78318
MA0141.10.563066
MA0142.11.04199
MA0143.10.887119
MA0144.10.439506
MA0145.10.21199
MA0146.10.0944145
MA0147.10.453952
MA0148.10.706718
MA0149.10.611881
MA0062.20.319836
MA0035.20.788288
MA0039.20.0220513
MA0138.20.951653
MA0002.20.965577
MA0137.20.559766
MA0104.20.386166
MA0047.20.845655
MA0112.20.211985
MA0065.20.609584
MA0150.10.67206
MA0151.10
MA0152.10.84577
MA0153.11.31015
MA0154.10.728853
MA0155.10.230016
MA0156.10.549102
MA0157.11.0083
MA0158.10
MA0159.10.465802
MA0160.10.71003
MA0161.10
MA0162.10.10667
MA0163.10.0996272
MA0164.10.817786
MA0080.20.534538
MA0018.20.828253
MA0099.20.944966
MA0079.22.24437
MA0102.21.8929
MA0258.10.419871
MA0259.10.441366
MA0442.10
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