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Coexpression cluster:C2332: Difference between revisions

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|full_id=C2332_pineal_Mast_medulla_acute_locus_caudate_hippocampus
|full_id=C2332_pineal_Mast_medulla_acute_locus_caudate_hippocampus
|id=C2332
|id=C2332
|ontology_enrichment_celltype=CL:0002274!2.70e-07!5;CL:0000457!2.70e-07!5;CL:0002191!2.70e-07!5;CL:0000097!2.70e-07!5;CL:0000831!2.70e-07!5;CL:0002028!2.70e-07!5
|ontology_enrichment_celltype=CL:0002274!2.54e-09!5;CL:0000457!2.54e-09!5;CL:0002191!2.54e-09!5;CL:0000097!2.54e-09!5;CL:0000831!2.54e-09!5;CL:0002028!2.54e-09!5
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!6.93e-68!115;UBERON:0001049!1.30e-56!57;UBERON:0005068!1.30e-56!57;UBERON:0006241!1.30e-56!57;UBERON:0007135!1.30e-56!57;UBERON:0001017!2.31e-52!82;UBERON:0005743!1.17e-50!86;UBERON:0000073!1.81e-48!94;UBERON:0001016!1.81e-48!94;UBERON:0002616!8.65e-47!59;UBERON:0002780!4.56e-43!41;UBERON:0001890!4.56e-43!41;UBERON:0006240!4.56e-43!41;UBERON:0000955!4.47e-42!69;UBERON:0006238!4.47e-42!69;UBERON:0003080!1.09e-41!42;UBERON:0003075!1.45e-40!86;UBERON:0007284!1.45e-40!86;UBERON:0002346!4.98e-39!90;UBERON:0002020!2.54e-35!34;UBERON:0003528!2.54e-35!34;UBERON:0001893!4.29e-35!34;UBERON:0002791!6.51e-34!33;UBERON:0001869!8.45e-33!32;UBERON:0003056!4.34e-28!61;UBERON:0000153!3.83e-25!129;UBERON:0007811!3.83e-25!129;UBERON:0002619!1.70e-24!22;UBERON:0004121!2.12e-24!169;UBERON:0000956!3.92e-24!25;UBERON:0000203!3.92e-24!25;UBERON:0000924!5.38e-24!173;UBERON:0006601!5.38e-24!173;UBERON:0000033!2.75e-23!123;UBERON:0001950!5.58e-22!20;UBERON:0003076!1.79e-15!15;UBERON:0003057!1.79e-15!15;UBERON:0004732!6.89e-13!13;UBERON:0002308!9.44e-13!9;UBERON:0000125!9.44e-13!9;UBERON:0002420!1.70e-12!9;UBERON:0007245!1.70e-12!9;UBERON:0010009!1.70e-12!9;UBERON:0010011!1.70e-12!9;UBERON:0000454!1.70e-12!9;UBERON:0004733!4.72e-12!12;UBERON:0002028!4.72e-12!12;UBERON:0007277!4.72e-12!12;UBERON:0009663!3.05e-10!7;UBERON:0000025!5.76e-10!194;UBERON:0001894!2.77e-09!7;UBERON:0006222!2.77e-09!7;UBERON:0002298!1.01e-08!8;UBERON:0004111!1.36e-08!241;UBERON:0000064!2.06e-08!219;UBERON:0002680!2.19e-08!9;UBERON:0001895!2.19e-08!9;UBERON:0010092!2.19e-08!9;UBERON:0000200!2.84e-08!6;UBERON:0001871!6.45e-08!7;UBERON:0000922!7.77e-08!612;UBERON:0000349!1.15e-07!5;UBERON:0001872!3.75e-07!5;UBERON:0000477!3.93e-07!286;UBERON:0000468!4.37e-07!659;UBERON:0002021!7.52e-07!5
|ontology_enrichment_uberon=UBERON:0007023!9.18e-73!114;UBERON:0001049!3.54e-68!56;UBERON:0005068!3.54e-68!56;UBERON:0006241!3.54e-68!56;UBERON:0007135!3.54e-68!56;UBERON:0000073!2.65e-63!53;UBERON:0002616!2.65e-63!53;UBERON:0001017!5.47e-62!81;UBERON:0001016!4.80e-58!89;UBERON:0000955!4.53e-52!68;UBERON:0006238!4.53e-52!68;UBERON:0002780!2.78e-50!41;UBERON:0001890!2.78e-50!41;UBERON:0003080!2.78e-50!41;UBERON:0006240!2.78e-50!41;UBERON:0003075!2.99e-45!82;UBERON:0007284!2.99e-45!82;UBERON:0003528!1.52e-42!34;UBERON:0002020!1.52e-42!34;UBERON:0002346!2.33e-42!86;UBERON:0001893!3.35e-42!34;UBERON:0002791!3.83e-39!32;UBERON:0001869!4.01e-39!32;UBERON:0010371!1.40e-33!104;UBERON:0002619!2.16e-32!22;UBERON:0003056!1.05e-31!61;UBERON:0001950!5.28e-29!20;UBERON:0000956!8.59e-28!25;UBERON:0000203!8.59e-28!25;UBERON:0004121!2.01e-25!171;UBERON:0000924!2.01e-25!171;UBERON:0006601!2.01e-25!171;UBERON:0011216!2.55e-25!223;UBERON:0010314!4.17e-25!132;UBERON:0003076!3.26e-18!15;UBERON:0003057!3.26e-18!15;UBERON:0000125!1.50e-16!9;UBERON:0002308!1.50e-16!9;UBERON:0002420!3.31e-16!9;UBERON:0007245!3.31e-16!9;UBERON:0010009!3.31e-16!9;UBERON:0010011!3.31e-16!9;UBERON:0000454!3.31e-16!9;UBERON:0004733!1.01e-13!12;UBERON:0002028!1.01e-13!12;UBERON:0007277!1.01e-13!12;UBERON:0000025!1.86e-13!192;UBERON:0000477!1.88e-13!373;UBERON:0009663!3.70e-13!7;UBERON:0004732!1.84e-12!13;UBERON:0002298!1.03e-11!6;UBERON:0000200!1.60e-10!6;UBERON:0004111!2.53e-10!240;UBERON:0000349!8.83e-10!5;UBERON:0001894!2.61e-09!7;UBERON:0006222!2.61e-09!7;UBERON:0002680!5.64e-09!9;UBERON:0001895!5.64e-09!9;UBERON:0010092!5.64e-09!9;UBERON:0001872!5.80e-09!5;UBERON:0000481!9.32e-09!342;UBERON:0001871!9.90e-09!6;UBERON:0000064!1.03e-08!218;UBERON:0002021!1.16e-08!5;UBERON:0002784!2.21e-08!4;UBERON:0000369!2.46e-08!4;UBERON:0002435!2.46e-08!4;UBERON:0000204!2.46e-08!4;UBERON:0010082!2.46e-08!4;UBERON:0000922!2.61e-08!592;UBERON:0005423!2.80e-07!581;UBERON:0000923!2.94e-07!560;UBERON:0010316!2.94e-07!560;UBERON:0005291!2.94e-07!560;UBERON:0006598!2.94e-07!560;UBERON:0010317!2.94e-07!560;UBERON:0002532!2.94e-07!560;UBERON:0002050!4.95e-07!564;UBERON:0001896!9.56e-07!3;UBERON:0005290!9.56e-07!3;UBERON:0010096!9.56e-07!3
|tf_chipseq_enrich=SUZ12#23512;3:37.5868356832972:3.12785741999833e-05:0.000631613111150822!ZNF263#10127;4:8.22184163701068:0.000218787118095832:0.00248449579502127
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}}
}}

Revision as of 13:53, 19 October 2012


Full id: C2332_pineal_Mast_medulla_acute_locus_caudate_hippocampus



Phase1 CAGE Peaks

Hg19::chr15:33602916..33602940,+p2@RYR3
Hg19::chr15:33602959..33602980,+p4@RYR3
Hg19::chr15:33602996..33603020,+p3@RYR3
Hg19::chr15:33603033..33603046,+p5@RYR3


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adult organism9.18e-73114
neural tube3.54e-6856
neural rod3.54e-6856
future spinal cord3.54e-6856
neural keel3.54e-6856
regional part of nervous system2.65e-6353
regional part of brain2.65e-6353
central nervous system5.47e-6281
nervous system4.80e-5889
brain4.53e-5268
future brain4.53e-5268
regional part of forebrain2.78e-5041
forebrain2.78e-5041
anterior neural tube2.78e-5041
future forebrain2.78e-5041
neural plate2.99e-4582
presumptive neural plate2.99e-4582
brain grey matter1.52e-4234
gray matter1.52e-4234
neurectoderm2.33e-4286
telencephalon3.35e-4234
regional part of telencephalon3.83e-3932
cerebral hemisphere4.01e-3932
ecto-epithelium1.40e-33104
regional part of cerebral cortex2.16e-3222
pre-chordal neural plate1.05e-3161
neocortex5.28e-2920
cerebral cortex8.59e-2825
pallium8.59e-2825
ectoderm-derived structure2.01e-25171
ectoderm2.01e-25171
presumptive ectoderm2.01e-25171
organ system subdivision2.55e-25223
structure with developmental contribution from neural crest4.17e-25132
posterior neural tube3.26e-1815
chordal neural plate3.26e-1815
neural nucleus1.50e-169
nucleus of brain1.50e-169
basal ganglion3.31e-169
nuclear complex of neuraxis3.31e-169
aggregate regional part of brain3.31e-169
collection of basal ganglia3.31e-169
cerebral subcortex3.31e-169
segmental subdivision of hindbrain1.01e-1312
hindbrain1.01e-1312
presumptive hindbrain1.01e-1312
tube1.86e-13192
anatomical cluster1.88e-13373
telencephalic nucleus3.70e-137
segmental subdivision of nervous system1.84e-1213
brainstem1.03e-116
gyrus1.60e-106
anatomical conduit2.53e-10240
limbic system8.83e-105
diencephalon2.61e-097
future diencephalon2.61e-097
regional part of metencephalon5.64e-099
metencephalon5.64e-099
future metencephalon5.64e-099
parietal lobe5.80e-095
multi-tissue structure9.32e-09342
temporal lobe9.90e-096
organ part1.03e-08218
occipital lobe1.16e-085
regional part of diencephalon2.21e-084
corpus striatum2.46e-084
striatum2.46e-084
ventral part of telencephalon2.46e-084
future corpus striatum2.46e-084
embryo2.61e-08592
developing anatomical structure2.80e-07581
germ layer2.94e-07560
germ layer / neural crest2.94e-07560
embryonic tissue2.94e-07560
presumptive structure2.94e-07560
germ layer / neural crest derived structure2.94e-07560
epiblast (generic)2.94e-07560
embryonic structure4.95e-07564
medulla oblongata9.56e-073
myelencephalon9.56e-073
future myelencephalon9.56e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
SUZ12#23512337.58683568329723.12785741999833e-050.000631613111150822
ZNF263#1012748.221841637010680.0002187871180958320.00248449579502127



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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