MCL coexpression mm9:2578

Phase1 CAGE Peaks

	Short description
Mm9::chr10:75029002..75029047,+	p6@Ggt1
Mm9::chr9:40273268..40273284,-	p19@Gramd1b
Mm9::chr9:40273298..40273319,-	p5@Gramd1b

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004662	CAAX-protein geranylgeranyltransferase activity	0.00372531294529364
GO:0004661	protein geranylgeranyltransferase activity	0.00558735708805877
GO:0008318	protein prenyltransferase activity	0.0074485847909816
GO:0004659	prenyltransferase activity	0.00837828014762047
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	0.0193450930206532

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
brush border epithelial cell	1.03e-07	6
gut absorptive cell	1.03e-07	6
absorptive cell	1.03e-07	6
enterocyte	1.03e-07	6

Uber Anatomy

Ontology term	p-value	n
intestine	4.93e-21	31
gastrointestinal system	2.00e-14	47
kidney	1.41e-11	14
kidney mesenchyme	1.41e-11	14
upper urinary tract	1.41e-11	14
kidney rudiment	1.41e-11	14
kidney field	1.41e-11	14
mucosa	1.94e-10	15
intestinal mucosa	1.28e-08	13
anatomical wall	1.28e-08	13
wall of intestine	1.28e-08	13
gastrointestinal system mucosa	1.28e-08	13
urinary system structure	3.07e-08	18
renal system	1.24e-07	19

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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