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MCL coexpression mm9:348: Difference between revisions

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{{MCL_coexpression_mm9
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of secondary male sexual characteristics;0.0428620973140022;20850!GO:0046543;development of secondary female sexual characteristics;0.0428620973140022;20850!GO:0001560;regulation of cell growth by extracellular stimulus;0.0428620973140022;235036!GO:0045136;development of secondary sexual characteristics;0.0428620973140022;20850!GO:0001553;luteinization;0.0428620973140022;20850!GO:0040008;regulation of growth;0.0428620973140022;20850,235036!GO:0001779;natural killer cell differentiation;0.0428620973140022;20850!GO:0045647;negative regulation of erythrocyte differentiation;0.0428620973140022;20850!GO:0045931;positive regulation of progression through mitotic cell cycle;0.0428620973140022;20850!GO:0045579;positive regulation of B cell differentiation;0.0428620973140022;20850!GO:0045885;positive regulation of survival gene product activity;0.0428620973140022;20850!GO:0006309;DNA fragmentation during apoptosis;0.0428620973140022;13347!GO:0019218;regulation of steroid metabolic process;0.0428620973140022;20850!GO:0030856;regulation of epithelial cell differentiation;0.0428620973140022;20850!GO:0000030;mannosyltransferase activity;0.0428620973140022;67556!GO:0042104;positive regulation of activated T cell proliferation;0.0428620973140022;20850!GO:0045086;positive regulation of interleukin-2 biosynthetic process;0.0428620973140022;20850!GO:0006921;cell structure disassembly during apoptosis;0.0428620973140022;13347!GO:0046006;regulation of activated T cell proliferation;0.0428620973140022;20850!GO:0045577;regulation of B cell differentiation;0.0428620973140022;20850!GO:0030262;apoptotic nuclear changes;0.0428620973140022;13347!GO:0045646;regulation of erythrocyte differentiation;0.0428620973140022;20850!GO:0031668;cellular response to extracellular stimulus;0.0428620973140022;235036!GO:0019915;sequestering of lipid;0.0438073878106892;20850!GO:0043029;T cell homeostasis;0.0438073878106892;20850!GO:0045884;regulation of survival gene product activity;0.0455952132937886;20850!GO:0045787;positive regulation of progression through cell cycle;0.0455952132937886;20850!GO:0030101;natural killer cell activation;0.0455952132937886;20850!GO:0045076;regulation of interleukin-2 biosynthetic process;0.0455952132937886;20850!GO:0006308;DNA catabolic process;0.0455952132937886;13347!GO:0050798;activated T cell proliferation;0.0455952132937886;20850!GO:0004289;subtilase activity;0.0455952132937886;18551!GO:0045621;positive regulation of lymphocyte differentiation;0.0455952132937886;20850!GO:0009991;response to extracellular stimulus;0.0455952132937886;235036!GO:0042094;interleukin-2 biosynthetic process;0.0455952132937886;20850!GO:0007595;lactation;0.0455952132937886;20850!GO:0032623;interleukin-2 production;0.0462434538972172;20850!GO:0050729;positive regulation of inflammatory response;0.0462434538972172;20850!GO:0031349;positive regulation of defense response;0.0462434538972172;20850!GO:0019216;regulation of lipid metabolic process;0.0462434538972172;20850!GO:0002260;lymphocyte homeostasis;0.0462434538972172;20850!GO:0045638;negative regulation of myeloid cell differentiation;0.0462434538972172;20850!GO:0051716;cellular response to stimulus;0.0462434538972172;235036!GO:0007346;regulation of progression through mitotic cell cycle;0.0462434538972172;20850!GO:0046489;phosphoinositide biosynthetic process;0.0462434538972172;67556!GO:0006506;GPI anchor biosynthetic process;0.0462434538972172;67556!GO:0042981;regulation of apoptosis;0.0462434538972172;20850,13347!GO:0043067;regulation of programmed cell death;0.0462434538972172;20850,13347!GO:0006505;GPI anchor metabolic process;0.0462434538972172;67556!GO:0040018;positive regulation of multicellular organism growth;0.0462434538972172;20850!GO:0030879;mammary gland development;0.0462434538972172;20850!GO:0022411;cellular component disassembly;0.0462434538972172;13347!GO:0045619;regulation of lymphocyte differentiation;0.0474254577769673;20850!GO:0045927;positive regulation of growth;0.048877223103783;20850!GO:0050871;positive regulation of B cell activation;0.048877223103783;20850!GO:0006997;nuclear organization and biogenesis;0.048877223103783;13347!GO:0001776;leukocyte homeostasis;0.048877223103783;20850!GO:0046661;male sex differentiation;0.048877223103783;20850!GO:0042102;positive regulation of T cell proliferation;0.048877223103783;20850!GO:0007259;JAK-STAT cascade;0.048877223103783;20850!GO:0048872;homeostasis of number of cells;0.048877223103783;20850!GO:0031347;regulation of defense response;0.048877223103783;20850!GO:0050727;regulation of inflammatory response;0.048877223103783;20850!GO:0022601;menstrual cycle phase;0.048877223103783;20850!GO:0009605;response to external stimulus;0.048877223103783;20850,235036!GO:0046474;glycerophospholipid biosynthetic process;0.048877223103783;67556!GO:0022602;menstrual cycle 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|gostat_on_MCL_coexpression=GO:0046544;development of secondary male sexual characteristics;0.0428620973140022;20850!GO:0046543;development of secondary female sexual characteristics;0.0428620973140022;20850!GO:0001560;regulation of cell growth by extracellular stimulus;0.0428620973140022;235036!GO:0045136;development of secondary sexual characteristics;0.0428620973140022;20850!GO:0001553;luteinization;0.0428620973140022;20850!GO:0040008;regulation of growth;0.0428620973140022;20850,235036!GO:0001779;natural killer cell differentiation;0.0428620973140022;20850!GO:0045647;negative regulation of erythrocyte differentiation;0.0428620973140022;20850!GO:0045931;positive regulation of progression through mitotic cell cycle;0.0428620973140022;20850!GO:0045579;positive regulation of B cell differentiation;0.0428620973140022;20850!GO:0045885;positive regulation of survival gene product activity;0.0428620973140022;20850!GO:0006309;DNA fragmentation during apoptosis;0.0428620973140022;13347!GO:0019218;regulation of steroid metabolic process;0.0428620973140022;20850!GO:0030856;regulation of epithelial cell differentiation;0.0428620973140022;20850!GO:0000030;mannosyltransferase activity;0.0428620973140022;67556!GO:0042104;positive regulation of activated T cell proliferation;0.0428620973140022;20850!GO:0045086;positive regulation of interleukin-2 biosynthetic process;0.0428620973140022;20850!GO:0006921;cell structure disassembly during apoptosis;0.0428620973140022;13347!GO:0046006;regulation of activated T cell proliferation;0.0428620973140022;20850!GO:0045577;regulation of B cell differentiation;0.0428620973140022;20850!GO:0030262;apoptotic nuclear changes;0.0428620973140022;13347!GO:0045646;regulation of erythrocyte differentiation;0.0428620973140022;20850!GO:0031668;cellular response to extracellular stimulus;0.0428620973140022;235036!GO:0019915;sequestering of lipid;0.0438073878106892;20850!GO:0043029;T cell homeostasis;0.0438073878106892;20850!GO:0045884;regulation of survival gene product activity;0.0455952132937886;20850!GO:0045787;positive regulation of progression through cell cycle;0.0455952132937886;20850!GO:0030101;natural killer cell activation;0.0455952132937886;20850!GO:0045076;regulation of interleukin-2 biosynthetic process;0.0455952132937886;20850!GO:0006308;DNA catabolic process;0.0455952132937886;13347!GO:0050798;activated T cell proliferation;0.0455952132937886;20850!GO:0004289;subtilase activity;0.0455952132937886;18551!GO:0045621;positive regulation of lymphocyte differentiation;0.0455952132937886;20850!GO:0009991;response to extracellular stimulus;0.0455952132937886;235036!GO:0042094;interleukin-2 biosynthetic process;0.0455952132937886;20850!GO:0007595;lactation;0.0455952132937886;20850!GO:0032623;interleukin-2 production;0.0462434538972172;20850!GO:0050729;positive regulation of inflammatory response;0.0462434538972172;20850!GO:0031349;positive regulation of defense response;0.0462434538972172;20850!GO:0019216;regulation of lipid metabolic process;0.0462434538972172;20850!GO:0002260;lymphocyte homeostasis;0.0462434538972172;20850!GO:0045638;negative regulation of myeloid cell differentiation;0.0462434538972172;20850!GO:0051716;cellular response to stimulus;0.0462434538972172;235036!GO:0007346;regulation of progression through mitotic cell cycle;0.0462434538972172;20850!GO:0046489;phosphoinositide biosynthetic process;0.0462434538972172;67556!GO:0006506;GPI anchor biosynthetic process;0.0462434538972172;67556!GO:0042981;regulation of apoptosis;0.0462434538972172;20850,13347!GO:0043067;regulation of programmed cell death;0.0462434538972172;20850,13347!GO:0006505;GPI anchor metabolic process;0.0462434538972172;67556!GO:0040018;positive regulation of multicellular organism growth;0.0462434538972172;20850!GO:0030879;mammary gland development;0.0462434538972172;20850!GO:0022411;cellular component disassembly;0.0462434538972172;13347!GO:0045619;regulation of lymphocyte differentiation;0.0474254577769673;20850!GO:0045927;positive regulation of growth;0.048877223103783;20850!GO:0050871;positive regulation of B cell activation;0.048877223103783;20850!GO:0006997;nuclear organization and biogenesis;0.048877223103783;13347!GO:0001776;leukocyte homeostasis;0.048877223103783;20850!GO:0046661;male sex differentiation;0.048877223103783;20850!GO:0042102;positive regulation of T cell proliferation;0.048877223103783;20850!GO:0007259;JAK-STAT cascade;0.048877223103783;20850!GO:0048872;homeostasis of number of cells;0.048877223103783;20850!GO:0031347;regulation of defense response;0.048877223103783;20850!GO:0050727;regulation of inflammatory response;0.048877223103783;20850!GO:0022601;menstrual cycle phase;0.048877223103783;20850!GO:0009605;response to external stimulus;0.048877223103783;20850,235036!GO:0046474;glycerophospholipid biosynthetic process;0.048877223103783;67556!GO:0022602;menstrual cycle process;0.048877223103783;20850!
|ontology_enrichment_celltype=CL:0000988!2.38e-12!32;CL:0002032!2.38e-12!32;CL:0000037!2.38e-12!32;CL:0000566!2.38e-12!32;CL:0000837!2.38e-12!32;CL:0002242!6.66e-11!16;CL:0002031!5.63e-10!25;CL:0000838!1.32e-09!12;CL:0000084!7.22e-09!11;CL:0000827!7.22e-09!11;CL:0000542!1.27e-08!13;CL:0000051!1.27e-08!13;CL:0000791!2.19e-08!9;CL:0000789!2.19e-08!9;CL:0002420!2.19e-08!9;CL:0002419!2.19e-08!9;CL:0000790!2.19e-08!9;CL:0000624!1.23e-07!8;CL:0002320!4.63e-07!46;CL:0000134!4.63e-07!46
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0004177!2.45e-09!29;UBERON:0005057!2.45e-09!29;UBERON:0002193!3.86e-09!48;UBERON:0002405!3.86e-09!48;UBERON:0002390!5.66e-09!45;UBERON:0003061!5.66e-09!45;UBERON:0000077!1.74e-08!35;UBERON:0000072!3.91e-08!27;UBERON:0002370!5.69e-08!23;UBERON:0000974!5.69e-08!23;UBERON:0004807!5.69e-08!23;UBERON:0005058!5.69e-08!23;UBERON:0003351!5.69e-08!23;UBERON:0009113!5.69e-08!23;UBERON:0003295!5.69e-08!23;UBERON:0009722!5.69e-08!23;UBERON:0005562!5.69e-08!23;UBERON:0007690!5.69e-08!23;UBERON:0006562!1.87e-07!24;UBERON:0001557!1.87e-07!24;UBERON:0001042!1.87e-07!24;UBERON:0008814!1.87e-07!24;UBERON:0009145!1.87e-07!24;UBERON:0002384!4.63e-07!46;UBERON:0003408!7.52e-07!24
}}

Latest revision as of 15:08, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr10:79785809..79785833,-p5@Pcsk4
Mm9::chr10:79785866..79785878,-p4@Pcsk4
Mm9::chr11:100721732..100721742,+p3@Stat5a
Mm9::chr11:23671230..23671264,-p6@Rel
Mm9::chr11:70051512..70051533,+p@chr11:70051512..70051533
+
Mm9::chr12:114067359..114067372,+p@chr12:114067359..114067372
+
Mm9::chr13:69673043..69673069,-p1@Papd7
Mm9::chr14:32308146..32308171,-p2@Mettl6
Mm9::chr17:57129821..57129833,+p@chr17:57129821..57129833
+
Mm9::chr19:10600074..10600095,+p@chr19:10600074..10600095
+
Mm9::chr19:53496109..53496137,+p@chr19:53496109..53496137
+
Mm9::chr1:174306731..174306755,+p2@Pigm
Mm9::chr2:132073579..132073599,+p@chr2:132073579..132073599
+
Mm9::chr3:87734359..87734371,+p4@Isg20l2
Mm9::chr3:90058266..90058285,+p3@Crtc2
Mm9::chr4:129488152..129488163,-p@chr4:129488152..129488163
-
Mm9::chr4:148478345..148478356,+p3@Dffa
Mm9::chr6:100621086..100621106,-p2@Shq1
Mm9::chr7:30638614..30638628,-p2@Zfp940
Mm9::chr7:71081571..71081581,+p@chr7:71081571..71081581
+
Mm9::chr9:120480504..120480537,-p@chr9:120480504..120480537
-
Mm9::chr9:20692745..20692756,+p4@Ppan


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0046544development of secondary male sexual characteristics0.0428620973140022
GO:0046543development of secondary female sexual characteristics0.0428620973140022
GO:0001560regulation of cell growth by extracellular stimulus0.0428620973140022
GO:0045136development of secondary sexual characteristics0.0428620973140022
GO:0001553luteinization0.0428620973140022
GO:0040008regulation of growth0.0428620973140022
GO:0001779natural killer cell differentiation0.0428620973140022
GO:0045647negative regulation of erythrocyte differentiation0.0428620973140022
GO:0045931positive regulation of progression through mitotic cell cycle0.0428620973140022
GO:0045579positive regulation of B cell differentiation0.0428620973140022
GO:0045885positive regulation of survival gene product activity0.0428620973140022
GO:0006309DNA fragmentation during apoptosis0.0428620973140022
GO:0019218regulation of steroid metabolic process0.0428620973140022
GO:0030856regulation of epithelial cell differentiation0.0428620973140022
GO:0000030mannosyltransferase activity0.0428620973140022
GO:0042104positive regulation of activated T cell proliferation0.0428620973140022
GO:0045086positive regulation of interleukin-2 biosynthetic process0.0428620973140022
GO:0006921cell structure disassembly during apoptosis0.0428620973140022
GO:0046006regulation of activated T cell proliferation0.0428620973140022
GO:0045577regulation of B cell differentiation0.0428620973140022
GO:0030262apoptotic nuclear changes0.0428620973140022
GO:0045646regulation of erythrocyte differentiation0.0428620973140022
GO:0031668cellular response to extracellular stimulus0.0428620973140022
GO:0019915sequestering of lipid0.0438073878106892
GO:0043029T cell homeostasis0.0438073878106892
GO:0045884regulation of survival gene product activity0.0455952132937886
GO:0045787positive regulation of progression through cell cycle0.0455952132937886
GO:0030101natural killer cell activation0.0455952132937886
GO:0045076regulation of interleukin-2 biosynthetic process0.0455952132937886
GO:0006308DNA catabolic process0.0455952132937886
GO:0050798activated T cell proliferation0.0455952132937886
GO:0004289subtilase activity0.0455952132937886
GO:0045621positive regulation of lymphocyte differentiation0.0455952132937886
GO:0009991response to extracellular stimulus0.0455952132937886
GO:0042094interleukin-2 biosynthetic process0.0455952132937886
GO:0007595lactation0.0455952132937886
GO:0032623interleukin-2 production0.0462434538972172
GO:0050729positive regulation of inflammatory response0.0462434538972172
GO:0031349positive regulation of defense response0.0462434538972172
GO:0019216regulation of lipid metabolic process0.0462434538972172
GO:0002260lymphocyte homeostasis0.0462434538972172
GO:0045638negative regulation of myeloid cell differentiation0.0462434538972172
GO:0051716cellular response to stimulus0.0462434538972172
GO:0007346regulation of progression through mitotic cell cycle0.0462434538972172
GO:0046489phosphoinositide biosynthetic process0.0462434538972172
GO:0006506GPI anchor biosynthetic process0.0462434538972172
GO:0042981regulation of apoptosis0.0462434538972172
GO:0043067regulation of programmed cell death0.0462434538972172
GO:0006505GPI anchor metabolic process0.0462434538972172
GO:0040018positive regulation of multicellular organism growth0.0462434538972172
GO:0030879mammary gland development0.0462434538972172
GO:0022411cellular component disassembly0.0462434538972172
GO:0045619regulation of lymphocyte differentiation0.0474254577769673
GO:0045927positive regulation of growth0.048877223103783
GO:0050871positive regulation of B cell activation0.048877223103783
GO:0006997nuclear organization and biogenesis0.048877223103783
GO:0001776leukocyte homeostasis0.048877223103783
GO:0046661male sex differentiation0.048877223103783
GO:0042102positive regulation of T cell proliferation0.048877223103783
GO:0007259JAK-STAT cascade0.048877223103783
GO:0048872homeostasis of number of cells0.048877223103783
GO:0031347regulation of defense response0.048877223103783
GO:0050727regulation of inflammatory response0.048877223103783
GO:0022601menstrual cycle phase0.048877223103783
GO:0009605response to external stimulus0.048877223103783
GO:0046474glycerophospholipid biosynthetic process0.048877223103783
GO:0022602menstrual cycle process0.048877223103783



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.13.5408
MA0004.10.873644
MA0006.11.68471
MA0007.10.421767
MA0009.10.483331
MA0014.10.732965
MA0017.10.239891
MA0019.10.329708
MA0024.10.445298
MA0025.10.694475
MA0027.12.07936
MA0028.16.59825
MA0029.10.426655
MA0030.10.43227
MA0031.10.402033
MA0038.10.243815
MA0040.10.494317
MA0041.10.10094
MA0042.10.0939798
MA0043.11.39663
MA0046.10.514989
MA0048.10.206983
MA0050.10.506524
MA0051.11.99697
MA0052.10.501416
MA0055.10.0581823
MA0056.10
MA0057.11.05677
MA0058.11.55577
MA0059.12.85928
MA0060.11.20594
MA0061.12.3811
MA0063.10
MA0066.10.235725
MA0067.10.798606
MA0068.10.341633
MA0069.10.501715
MA0070.10.493176
MA0071.10.169125
MA0072.10.485733
MA0073.13.8418
MA0074.10.209912
MA0076.17.14289
MA0077.10.466808
MA0078.10.275441
MA0081.10.717402
MA0083.10.568641
MA0084.11.11388
MA0087.10.530004
MA0088.13.73648
MA0089.10
MA0090.10.392445
MA0091.10.153118
MA0092.10.124428
MA0093.10.496926
MA0095.10
MA0098.10
MA0100.10.584206
MA0101.12.26127
MA0103.10.253989
MA0105.13.9296
MA0106.11.40621
MA0107.12.45659
MA0108.20.348212
MA0109.10
MA0111.10.132626
MA0113.10.259904
MA0114.10.145706
MA0115.10.571881
MA0116.10.453258
MA0117.10.542889
MA0119.10.101951
MA0122.10.560692
MA0124.10.748494
MA0125.10.67944
MA0130.10
MA0131.11.56694
MA0132.10
MA0133.10
MA0135.10.602346
MA0136.11.19199
MA0139.10.425271
MA0140.10.201717
MA0141.10.0822433
MA0142.10.389844
MA0143.10.27232
MA0144.10.344625
MA0145.11.7347
MA0146.12.28351
MA0147.13.72014
MA0148.10.155077
MA0149.10.104621
MA0062.212.8238
MA0035.20.205003
MA0039.23.02406
MA0138.20.319705
MA0002.20.227684
MA0137.20.981229
MA0104.24.26801
MA0047.20.243248
MA0112.20.22235
MA0065.20.00234821
MA0150.10.135628
MA0151.10
MA0152.10.243327
MA0153.10.617506
MA0154.10.201776
MA0155.10.654367
MA0156.13.21167
MA0157.10.363212
MA0158.10
MA0159.10.696166
MA0160.10.156994
MA0161.10
MA0162.14.18474
MA0163.11.48165
MA0164.10.637671
MA0080.20.528447
MA0018.21.89645
MA0099.20.314682
MA0079.23.37134
MA0102.21.16504
MA0258.10.131525
MA0259.11.87279
MA0442.10
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