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{{Coexpression_clusters
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hormone activity!0.000618156128576475!7200$GO:0007628!adult walking behavior!0.00206052042858825!7200$GO:0009755!hormone-mediated signaling!0.00206052042858825!7200$GO:0008344!adult locomotory behavior!0.00216354645001766!7200$GO:0030534!adult behavior!0.00333804309431296!7200$GO:0005184!neuropeptide hormone activity!0.00339985870717061!7200$GO:0009725!response to hormone stimulus!0.00671140939597315!7200$GO:0007626!locomotory behavior!0.0139857824090427!7200$GO:0005179!hormone activity!0.0144648534086895!7200$GO:0005625!soluble fraction!0.0144648534086895!7200$GO:0007610!behavior!0.0165216274364985!7200$GO:0009719!response to endogenous stimulus!0.0272503826680796!7200$GO:0042221!response to chemical stimulus!0.0280072276716572!7200$GO:0007267!cell-cell signaling!0.0282585658777817!7200$GO:0000267!cell fraction!0.037171788531732!7200$GO:0005102!receptor 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|full_id=C430_acute_giant_chronic_CD34_CD133_melanoma_skeletal
|gostat_on_coexpression_clusters=GO:0008437!thyrotropin-releasing hormone activity!0.000618156128576475!7200$GO:0007628!adult walking behavior!0.00206052042858825!7200$GO:0009755!hormone-mediated signaling!0.00206052042858825!7200$GO:0008344!adult locomotory behavior!0.00216354645001766!7200$GO:0030534!adult behavior!0.00333804309431296!7200$GO:0005184!neuropeptide hormone activity!0.00339985870717061!7200$GO:0009725!response to hormone stimulus!0.00671140939597315!7200$GO:0007626!locomotory behavior!0.0139857824090427!7200$GO:0005179!hormone activity!0.0144648534086895!7200$GO:0005625!soluble fraction!0.0144648534086895!7200$GO:0007610!behavior!0.0165216274364985!7200$GO:0009719!response to endogenous stimulus!0.0272503826680796!7200$GO:0042221!response to chemical stimulus!0.0280072276716572!7200$GO:0007267!cell-cell signaling!0.0282585658777817!7200$GO:0000267!cell fraction!0.037171788531732!7200$GO:0005102!receptor binding!0.0400642440833628!7200
|id=C430
|ontology_enrichment_celltype=CL:0000763!1.41e-18!112;CL:0000049!1.41e-18!112;CL:0002057!3.03e-18!42;CL:0002009!2.17e-16!65;CL:0002194!2.76e-16!63;CL:0000576!2.76e-16!63;CL:0000040!2.76e-16!63;CL:0000559!2.76e-16!63;CL:0000557!2.87e-16!71;CL:0000860!2.35e-15!45;CL:0000766!2.46e-14!76;CL:0000839!2.81e-14!70;CL:0000037!3.91e-09!172;CL:0000566!3.91e-09!172;CL:0000988!2.33e-08!182;CL:0002032!7.76e-08!165;CL:0000837!7.76e-08!165
|ontology_enrichment_disease=DOID:8692!6.81e-08!31
|ontology_enrichment_uberon=UBERON:0007023!1.82e-23!115;UBERON:0001049!1.01e-17!57;UBERON:0005068!1.01e-17!57;UBERON:0006241!1.01e-17!57;UBERON:0007135!1.01e-17!57;UBERON:0005743!1.08e-15!86;UBERON:0001017!6.82e-15!82;UBERON:0003075!6.89e-15!86;UBERON:0007284!6.89e-15!86;UBERON:0002616!1.52e-14!59;UBERON:0000073!3.27e-14!94;UBERON:0001016!3.27e-14!94;UBERON:0002390!1.18e-13!102;UBERON:0003061!1.18e-13!102;UBERON:0002371!1.25e-13!80;UBERON:0002346!2.83e-13!90;UBERON:0000955!6.78e-13!69;UBERON:0006238!6.78e-13!69;UBERON:0002193!1.42e-12!112;UBERON:0003080!3.46e-12!42;UBERON:0002780!7.28e-12!41;UBERON:0001890!7.28e-12!41;UBERON:0006240!7.28e-12!41;UBERON:0001474!3.12e-11!86;UBERON:0002405!8.14e-10!115;UBERON:0003056!9.61e-10!61;UBERON:0002020!1.13e-09!34;UBERON:0003528!1.13e-09!34;UBERON:0001893!1.32e-09!34;UBERON:0002791!2.56e-09!33;UBERON:0004765!4.57e-09!101;UBERON:0001434!4.57e-09!101;UBERON:0001869!1.75e-08!32;UBERON:0003081!2.84e-07!216;UBERON:0003076!5.94e-07!15;UBERON:0003057!5.94e-07!15;UBERON:0001950!5.95e-07!20;UBERON:0000956!8.98e-07!25;UBERON:0000203!8.98e-07!25
|tfbs_overrepresentation=0.705141,0.370939,0.629526,0.312596,0.818862,0.264469,0.286108,0.231443,0.225122,0.180986,0.00654595,0.858832,0.79889,0.276126,0.708895,0.387308,0.113027,0.54727,0.340514,0.58385,0.475914,0.663925,0.480948,0.534399,0.277858,0.28568,0.834918,0.16599,0.118305,0.173887,0.827676,0.237909,0.130209,0.266745,0.410089,0.491667,0.0705853,0.285884,0.25803,0.410956,0.5406,0.173908,0.321652,0.0214977,0.627697,0.246489,0.257064,0.200139,0.595249,0.628619,0.138942,0.0689489,0.427497,0.0402831,0.242552,0.259426,0.0582524,0.547069,0.4649,0.211238,0.204685,0.710825,0.585794,0.454235,0.349628,0.327796,0.64648,0.377773,0.152347,0.408636,0.706286,0.415651,0.510774,0.254928,0.0559081,0.123985,0.183305,0.290028,0.25251,0.0542767,0.537273,0.138057,0.283201,0.607527,0.49159,0.891861,0.399424,0.108358,0.927958,0.391535,0.151431,0.322891,0.536306,0.310703,0.495555,0.608143,0.964001,0.365648,0.172019,0.703612,0.364853,0.237817,0.327604,0.25142,0.565088,0.274132,0.412331,0.612434,0.3352,0.22247,0.786858,0.232931,0.711177,0.127857,0.558762,0.23144,0.145755,0.360548,0.318353,0.0307455,0.752958,0.843239,0.6857,0.0326504,0.201293,0.775221,0.517533,0.107977,0.491191,0.305093,0.37558,0.449173,0.36346,0.161981,0.00415225,0.584005,0.401994,0.353661,0.227084,0.0299268,0.161914,0.648873,0.521652,0.727541,0.82326,0.105965,0.549655,0.490624,0.262525,0.259575,0.247262,0.695522,0.451542,0.186616,0.284398,0.0728699,0.448829,0.590663,0.334334,0.231273,0.318213,0.535914,0.246171,0.706553,0.913655,0.238663,0.268915,0.64814,0.270793,0.780265,0.0194624,0.106951,0.951498,0.347337,0.47202,0.164089,0.111806,0.200868,0.192904,0.242839,0.734507,0.632722,0.191882,0.609993,0.444086,0.253213,0.458716,0.269752,0.484805,0.429206,0.580576,0.796071,0.6342,0.591818,0.60007,0.309034,0.130103,0.379177,0.415515,0.589595,0.511868,0.0834959,0.21345,0.380785,0.310017,0.404589,0.443422,0.0394623,0.8299,0.778233,0.302299,0.570429,0.628466,0.600861,0.547884,0.758243,0.747201,0.557713,0.392768,0.565377,0.690727,0.478853,0.14308,0.153628,0.444708,0.645792,0.317804,0.498021,0.380024,0.3772,0.625933,0.317484,0.279407,0.456742,0.538416,0.527638,0.00645604,0.903723,0.745571,0.553025,0.786603,0.638723,0.54803,0.485762,0.0709444,0.676375,0.478922,0.230311,0.289068,0.247399,0.383085,0.208892,0.793062,0.187973,0.0462097,0.736508,0.580924,0.515585,0.424744,0.96275,0.387416,0.771401,0.396926,0.282963,0.236067,0.476994,0.477413,0.523109,0.618379,0.452279,0.456444,0.090591,0.19147,0.475163,0.500614,0.257237,0.0235284,0.665015,0.170045,0.288437,0.252312,0.608399,0.913499,0.807844,0.819805,0.236613,0.674773,0.173076,0.873046,0.775032,0.416262,0.370321,0.193922,0.19584,0.532547,0.0368515,0.037718,0.052726,0.109682,0.543099,0.354044,0.166561,0.795983,0.968414,0.45465,0.25161,0.0617614,0.594616,0.562964,0.926298,0.702006,0.343672,0.406854,0.515246,0.00543935,0.149308,0.394381,0.881938,0.189,0.916661,0.760992,0.566443,0.559034,0.132106,0.292698,0.563115,0.25496,0.329872,0.490459,0.273655,0.0913475,0.219222,0.592313,0.495644,0.553446,0.819467,0.072408,0.343024,0.297035,0.456675,0.906181,0.846921,0.486994,0.448258,0.341858,0.210091,0.230038,0.00304845,0.436322,0.481071,0.173707,0.801625,0.21074,0.643381,0.465218,0.54214,0.158437,0.412628,0.441175,0.791207,0.969479,0.424704,0.230791,0.58241,0.351161,0.723972,0.276711,0.832638,0.563788,0.164362,0.426826,0.298032,0.120474,0.592335,0.554351,0.810239,0.618177,0.133637,0.960211,0.379441,0.485872,0.806354,0.519382,0.712238,0.882156,0.00475843,0.140156,0.384753,0.239635,0.374277,0.882894,0.789182,0.245593,0.787706,0.974982,0.881812,0.0974745,0.698594,0.700561,0.512811,0.876068,0.476645,0.509652,0.652301,0.136081,0.306239,0.677121,0.404109,0.670437,0.548746,0.722604,0.497959,0.473405,0.960407,0.532129,0.939071,0.174859,0.292359,0.212405,0.72637,0.0878717,0.258611,0.584883,0.213746,0.592941,0.45597,0.208297,0.743988,0.104036,0.21764,0.293613,0.281221,0.222252,0.958299,0.862637,0.00459224,0.690252,0.100238,0.813135,0.736371,0.347607,0.0295362,0.00485791,0.800299,0.511195,0.375501,0.216804,0.625393,0.634688,0.707277,0.237638,0.229252,0.906568,0.264913,0.148987,0.33346,0.425621,0.355482,0.226937,0.463449,0.365276,0.697276,0.0144377,0.254935,0.167014,0.291794,0.804534,0.597508,0.268058,0.289141,0.76396,0.27774,0.670622,0.0574839,0.913516,0.391761,0.711526,0.129386,0.76511,0.460373,0.183643,0.305745,0.759458,0.606632,0.05437,0.51454,0.501059,0.736884,0.216042,0.290992,0.0294438,0.636297,0.28639,0.540365,0.49119,0.112361,0.325009,0.143197,0.410912,0.456103,0.229141,0.565912,0.202251,0.811493,0.662804,0.476095,0.31516,0.819222,0.565271,0.649342,0.0177483,0.790602,0.758637,0.505008,0.535715,0.0831241,0.130264,0.580208,0.706084,0.0363147,0.181889,0.113286,0.83841,0.208692,0.660864,0.0484692,0.0648892,0.834072,0.0406198,0.471391,0.544257,0.386603,0.636087,0.517371,0.356122,0.252405,0.486562,0.312873,0.106633,0.406066,0.275859,0.299023,0.472971,0.453517,0.391891,0.489806,0.351389,0.463331,0.358096,0.278964,0.236241,0.262123,0.894968,0.761017,0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}}

Latest revision as of 11:22, 17 September 2013


Full id: C430_acute_giant_chronic_CD34_CD133_melanoma_skeletal



Phase1 CAGE Peaks

Hg19::chr11:1918273..1918293,+p@chr11:1918273..1918293
+
Hg19::chr11:1918296..1918324,+p@chr11:1918296..1918324
+
Hg19::chr11:47611749..47611769,-p@chr11:47611749..47611769
-
Hg19::chr13:44989025..44989034,-p@chr13:44989025..44989034
-
Hg19::chr17:73494329..73494345,+p@chr17:73494329..73494345
+
Hg19::chr19:853278..853299,+p2@ELANE
Hg19::chr19:855662..855672,+p6@ELANE
Hg19::chr19:856037..856044,+p@chr19:856037..856044
+
Hg19::chr19:856109..856117,+p@chr19:856109..856117
+
Hg19::chr1:243432977..243432992,+p@chr1:243432977..243432992
+
Hg19::chr1:243433014..243433053,+p@chr1:243433014..243433053
+
Hg19::chr1:35333189..35333201,-p@chr1:35333189..35333201
-
Hg19::chr1:35333224..35333237,-p@chr1:35333224..35333237
-
Hg19::chr1:45190613..45190615,-p@chr1:45190613..45190615
-
Hg19::chr20:60881426..60881443,+p@chr20:60881426..60881443
+
Hg19::chr20:60881449..60881460,+p@chr20:60881449..60881460
+
Hg19::chr2:127851314..127851361,-p@chr2:127851314..127851361
-
Hg19::chr3:129693504..129693519,+p3@TRH
Hg19::chr3:129693523..129693541,+p2@TRH
Hg19::chr7:29900040..29900050,+p@chr7:29900040..29900050
+
Hg19::chr7:29900084..29900122,+p@chr7:29900084..29900122
+
Hg19::chr7:29900130..29900140,+p@chr7:29900130..29900140
+
Hg19::chr8:53062376..53062387,-p@chr8:53062376..53062387
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0008437thyrotropin-releasing hormone activity0.000618156128576475
GO:0007628adult walking behavior0.00206052042858825
GO:0009755hormone-mediated signaling0.00206052042858825
GO:0008344adult locomotory behavior0.00216354645001766
GO:0030534adult behavior0.00333804309431296
GO:0005184neuropeptide hormone activity0.00339985870717061
GO:0009725response to hormone stimulus0.00671140939597315
GO:0007626locomotory behavior0.0139857824090427
GO:0005179hormone activity0.0144648534086895
GO:0005625soluble fraction0.0144648534086895
GO:0007610behavior0.0165216274364985
GO:0009719response to endogenous stimulus0.0272503826680796
GO:0042221response to chemical stimulus0.0280072276716572
GO:0007267cell-cell signaling0.0282585658777817
GO:0000267cell fraction0.037171788531732
GO:0005102receptor binding0.0400642440833628



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
occipital pole5.05e-341
pole of cerebral hemisphere5.05e-341
pons2.89e-123
thymus1.70e-094
hemolymphoid system gland1.70e-094
thymic region1.70e-094
pharyngeal gland1.70e-094
thymus primordium1.70e-094
occipital lobe6.55e-085
brainstem8.97e-076
pharyngeal epithelium9.49e-076


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.522796
MA0004.10.454064
MA0006.10.490927
MA0007.10.840085
MA0009.11.27126
MA0014.10.37798
MA0017.10.0812903
MA0019.10.250001
MA0024.10.419164
MA0025.10.630648
MA0027.12.07466
MA0028.11.35603
MA0029.10.435662
MA0030.10.425859
MA0031.10.371592
MA0038.10.21714
MA0040.10.440685
MA0041.10.160207
MA0042.10.140252
MA0043.10.510506
MA0046.10.500598
MA0048.10.302432
MA0050.10.434675
MA0051.10.613549
MA0052.10.444013
MA0055.10.168686
MA0056.10
MA0057.10.021569
MA0058.10.312452
MA0059.10.0932742
MA0060.10.0226691
MA0061.12.66147
MA0063.10
MA0066.10.217443
MA0067.10.802392
MA0068.10.0481509
MA0069.10.497197
MA0070.10.487346
MA0071.10.190167
MA0072.11.21395
MA0073.10.00748595
MA0074.10.213609
MA0076.10.102323
MA0077.10.476645
MA0078.11.42963
MA0081.11.58302
MA0083.10.516887
MA0084.10.981601
MA0087.10.481255
MA0088.10.55557
MA0089.10
MA0090.10.110205
MA0091.10.458145
MA0092.10.127244
MA0093.10.497967
MA0095.10
MA0098.10
MA0100.10.227084
MA0101.10.505635
MA0103.10.469617
MA0105.11.46485
MA0106.10.247115
MA0107.11.85282
MA0108.20.369058
MA0109.10
MA0111.10.117802
MA0113.10.259368
MA0114.10.600893
MA0115.10.730438
MA0116.10.349495
MA0117.11.34244
MA0119.10.288423
MA0122.10.567011
MA0124.10.691722
MA0125.10.614264
MA0130.10
MA0131.11.4809
MA0132.10
MA0133.10
MA0135.10.537249
MA0136.10.632521
MA0139.10.0657272
MA0140.10.188358
MA0141.10.092378
MA0142.10.345512
MA0143.10.259501
MA0144.10.302438
MA0145.10.0315697
MA0146.10.549621
MA0147.10.155334
MA0148.10.164295
MA0149.11.02619
MA0062.20.184791
MA0035.20.550801
MA0039.20.0451247
MA0138.20.288795
MA0002.20.0879293
MA0137.20.255519
MA0104.20.241164
MA0047.20.238164
MA0112.20.588343
MA0065.20.0834708
MA0150.10.10696
MA0151.10
MA0152.10.192836
MA0153.10.598889
MA0154.10.235715
MA0155.10.0627913
MA0156.10.933234
MA0157.10.323429
MA0158.10
MA0159.10.156031
MA0160.10.174237
MA0161.10
MA0162.10.137435
MA0163.10.291129
MA0164.10.268764
MA0080.20.230472
MA0018.20.693153
MA0099.20.193081
MA0079.20.0997759
MA0102.21.01759
MA0258.10.118144
MA0259.10.164631
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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