FFCP PHASE1:Hg19::chr15:39883408..39883415,+: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{FFCP
|id=chr15:39883408..39883415,+
|short_description=p37@THBS1
|description=CAGE_peak_37_at_THBS1_5end
|association_with_transcript=279bp_to_ENST00000560894_5end
|Ent...") |
No edit summary |
||
(11 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
{{FFCP | {{FFCP | ||
| | |DHSsupport=supported | ||
| | |DPIdataset=robust | ||
|EntrezGene=7057 | |EntrezGene=7057 | ||
|GencodeV16b_All_Build2_RSEM10_CPAT_consensus=gencodeV16_protein_coding | |||
|HGNC=11785 | |HGNC=11785 | ||
|TSSclassifier=strong | |||
|UniProt= | |UniProt= | ||
|association_with_transcript=279bp_to_ENST00000560894_5end | |||
|cluster_id=chr15:39883408..39883415,+ | |||
|coexpression_cluster_id=C453 | |||
|description=CAGE_peak_37_at_THBS1_5end | |||
|id=chr15:39883408..39883415,+ | |||
|ontology_enrichment_celltype=CL:0000057!9.51e-11!75;CL:0002139!2.10e-10!24;CL:0002371!2.45e-10!591;CL:0000063!6.38e-10!578;CL:0000548!8.60e-10!679;CL:0000004!8.60e-10!679;CL:0000255!8.60e-10!679;CL:0000012!1.77e-09!682;CL:0000071!2.12e-09!18;CL:0002546!2.12e-09!18;CL:0000144!5.60e-09!625;CL:0000115!9.56e-08!35;CL:0000076!6.37e-07!62 | |||
|ontology_enrichment_celltype_v019=CL:0002544;4.35e-12;6!CL:1000413;4.94e-11;9!CL:0002580;8.78e-10;3!CL:0002559;7.14e-09;5!CL:0000197;2.12e-07;6!CL:0000098;2.12e-07;6!CL:0002167;2.12e-07;6!CL:0002617;6.28e-07;2!CL:0002545;7.60e-07;2!CL:0000071;7.79e-07;18 | |||
|ontology_enrichment_celltype_v019_2=CL:0002544,7.27e-12,6;CL:1000413,7.92e-11,9;CL:0002580,4.41e-10,3;CL:0000057,3.35e-09,76;CL:0002559,8.73e-09,5;CL:0000197,1.37e-07,6;CL:0000098,1.37e-07,6;CL:0002167,1.37e-07,6;CL:0002617,3.60e-07,2;CL:0000071,9.85e-07,18;CL:0002546,9.85e-07,18 | |||
|ontology_enrichment_development_v019=CL:0002546;7.79e-07;18 | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_disease_v019=DOID:17;3.11e-14;5!DOID:450;3.11e-14;5!DOID:66;3.11e-14;5!DOID:423;3.11e-14;5!DOID:0080000;3.11e-14;5!DOID:11722;3.11e-14;5!DOID:3307;7.60e-07;2 | |||
|ontology_enrichment_disease_v019_2=DOID:17,5.92e-14,5;DOID:450,5.92e-14,5;DOID:66,5.92e-14,5;DOID:423,5.92e-14,5;DOID:0080000,5.92e-14,5;DOID:11722,5.92e-14,5;DOID:3307,4.43e-07,2 | |||
|ontology_enrichment_uberon=UBERON:0003102!2.92e-10!95;UBERON:0001986!2.12e-09!18;UBERON:0004638!2.12e-09!18;UBERON:0004852!2.12e-09!18;UBERON:0002199!3.87e-09!45;UBERON:0002416!3.87e-09!45;UBERON:0000487!4.11e-09!22;UBERON:0002097!5.36e-08!40;UBERON:0000055!2.22e-07!69;UBERON:0006914!2.34e-07!25;UBERON:0004872!3.98e-07!84;UBERON:0001981!4.88e-07!60;UBERON:0007500!4.88e-07!60;UBERON:0004537!4.88e-07!60;UBERON:0006965!4.88e-07!60 | |||
|ontology_enrichment_uberon_v019=UBERON:0003915;4.94e-11;9!UBERON:0004700;4.94e-11;9!UBERON:0001917;4.94e-11;9!UBERON:0002073;7.14e-09;5!UBERON:0003688;3.30e-08;6!UBERON:0002358;3.30e-08;6!UBERON:0003684;3.30e-08;6!UBERON:0001178;3.30e-08;6!UBERON:0000310;2.62e-07;10!UBERON:0000487;5.82e-07;22!UBERON:0005800;7.60e-07;2!UBERON:0001515;7.60e-07;2!UBERON:0004638;7.79e-07;18!UBERON:0001986;7.79e-07;18!UBERON:0004852;7.79e-07;18 | |||
|ontology_enrichment_uberon_v019_2=UBERON:0003915,7.92e-11,9;UBERON:0004700,7.92e-11,9;UBERON:0001917,7.92e-11,9;UBERON:0002073,8.73e-09,5;UBERON:0005086,8.73e-09,5;UBERON:0003688,2.28e-08,6;UBERON:0002358,2.28e-08,6;UBERON:0003684,2.28e-08,6;UBERON:0001178,2.28e-08,6;UBERON:0000310,1.47e-07,10;UBERON:0002097,4.48e-07,41;UBERON:0000487,6.61e-07,22;UBERON:0001443,7.88e-07,11;UBERON:0004638,9.85e-07,18;UBERON:0001986,9.85e-07,18;UBERON:0004852,9.85e-07,18 | |||
|phase1_expression=1.99846217197612,4.06790995392868,0.563817616383885,4.00293193412522,1.78784437770915,2.61701557230111,0,0.631719873426831,0.261185628199839,0.245733936501509,0,0.436882744260345,0.263766978228454,0,0,0,0,0,0,0,0,0,0,0,0.125542639594803,0,0,0,0,0,0,0,0,0,0,0,0,0,1.00272223735071,0,0,0.32389366601898,0,0,0,0,0.697287110717054,0,0,2.01384674625505,0,0.236482229888585,1.37898272294647,0.645484683583826,0,0.564727018627814,0,0.224723484445085,1.22433556948361,0,0,0,0,0,3.19230162491442,0.56738522469114,0.622822248995575,0.75374599577023,0,0,0.605399502633369,0,0,0,0,0,0,0.300353785683013,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.12786256184353,0,1.00267582127178,0.144846518960824,1.5905718941022,0.973269740605272,0,0,0,0,0,0,0,0,0,0,0,0,1.19257444420023,0,2.08284300964557,2.82653970962005,0,1.37559020970034,0.208994966536811,0,0.71153252537342,0.66944122552934,0.805658634218294,0.760272105718513,0.732186172644509,1.10298924103761,3.24056779152704,0.535798369704479,0.898117490504679,1.46394924628319,0,0.949265659568129,0.183201743930407,0,0,0,7.45457927542978,0.633152558322899,0.662045904066094,1.43418310374407,0,0,2.1349799145941,0.49333509683432,0,0.134710672069688,0.163461903113459,0,0,0,0,0,0.149448680551801,0,0,0,0.61246251376468,0,0.103325781175765,3.56400857184616,6.92347401979959,0,0,0,0,0.277064115484183,1.31693286264251,3.0648779579902,3.15499923703853,0.113432183160021,3.04962380671065,2.56268866582281,1.48352330811693,1.20036438433761,1.03052529238439,0.772921620136887,0.744467425326359,0.843881661206331,0.487185025805993,0.252433774244115,0.828449087780694,0.161646056818812,0.710019185033229,0.403008392910561,0.847802961552438,0.193260853163297,0.818238361772504,0.286804595389004,0,0,0,0,0,0,0,1.28648187638577,1.38134921352481,1.39310378409594,1.44375896333917,0.118306800039844,0,0.241011029883482,0,0.217879444092406,0,0,0,0.38474715694639,0,0,0,0,0,0,0,0,0.122988438543114,0,0.219500570817251,1.1240175325762,0.100528972411631,0.185176890317059,0,0,0,0,0.117408694235822,0.721832238805369,0,0.761016608938393,0.790204397959275,0.858486162094873,0,0,0,0.93733833986777,1.51183915378974,0.141775097242386,0.358234090811393,0.290633938513962,0.766765358330422,0,0,0,0,0,0,0,0,0,0.102827492703324,0,0,0.112131084345361,0,0.07333828582095,0,0,0.845302752556,0,1.04007436911366,0,0,0,0.142977993658148,0,0,0,0,0,0,0,0,0,0,0,0.479249710983165,0,0,0.434343920002738,0.205476322550383,0.358121926479791,0,0,0,0,0,0,0,0,0,0,0,0,0.12269149171914,0,0,1.66376689224646,1.60586089917446,1.89242898040722,1.17141414992713,0.300946099727719,0,0,0,0.184369168541703,0.347534457872331,0,0,0,0,0,0.606255142892519,0,0,1.98486246255021,3.6830873589135,4.49056151092918,0.640695746278505,2.55853624533352,2.73451665944133,0,0.308419387605311,0.177561725313127,0.164254312027618,0,0,0,0.601519410909855,0,0.34444334449382,0.364182336013434,0,0,0,0,0,0,0,0.170093705276516,0,4.62681758070868,0,0,0.254876273045038,0,0,0,0,0,0,0,0,0.0915694648183434,0,0,2.60024098414608,1.6068392984416,0,0,0,0.137836572484531,0,0,0,0,0.661139661443912,1.15314040419064,2.55225424989168,0.50578890427775,0,0,0,0,0,0.869932992075073,0.9266210955196,0.143124886741991,0,0,0.190630193923825,0,0,0,0,0.179872457583315,0.274537029736055,0,0,0,0,0.48763373908959,0.243713489631284,2.11300293513511,0,0.282810863907425,0,0,0.66343897524122,0.876901770507525,0,0,1.01455188481352,0.6196469961995,0,0,0.294747123039363,0.35667105148125,0,0,0,0,0.349934720244983,0,0,0,0,0.86101074534246,1.68471475667626,0,0.689170200620878,0,0,0,0,0,0,0,0,0,1.92495971052672,0,0,0,0,0,0,0,0,0,0,0,0,0,0.169291777801603,0,0,0,0,0,0,0,0,0,0,0.270455678475983,0,0,0,0,0,0,0,1.67121139316383,0.593929361665277,2.45728561679386,0,0,0,0,0,0,0,0,0,0,1.55519793830904,0.629078458031288,0,0,0.197286811273867,0,2.22273980289274,0,0,0,0.260427761085233,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.227884111694002,0,0,0,0.31900115973192,1.00757352742049,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0884575645033392,0,0,0,0,0,0,0,0,0,0,0,0,0,0.126373159256976,0,0,0,0,0,0,0,0,0,0.0979923974143777,0.0870592065804026,0.17472666824203,0,0,0,0,0,0,0,0,0,0,0,0.801588202515337,0,0,0,0,0,0,0,0.235694034616795,0,0,0.407992870545287,0,0,0,0,1.28929632425987,0,0.279282401272254,0,0,0,0,0,0,8.28689732147528,0,0.0787831823072236,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.104909176269996,0,0,0.191915197319445,0,0,0,0,0,0,0,0,1.87426823963964,0,0,0,0,0,0.171086837884329,0,0.640724475406168,0.157204305099666,0,0,0,0,0,0,0,0.306345576763462,0,0,0,0,0,0,0,0,0,0.124980407962107,0,0,0,0.468334905806882,0,0.149254802886874,0,0.554805861502613,0,0,0,0,0,0.15543720058278,0,0.159296767163702,0,0.465788870628778,0,0.53168342911599,0,0,0.380805212168795,0,0.181848659202559,0.107410557042488,0.464033759878494,0.398095888698616,2.40016658797892,0,0.336749488765919,0,0,0,0,1.58694147858591,0.231522474323834,0.489473409012935,0.358177682162975,0,0,0,0,0,0.76872455576384,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2.22603045457393,0,0,0.352675943690684,0.918736432059601,0,0,0,0,0,0,0,0,0.0981477185010256,0,0,0.231051332300676,0.381382095467167,0,0,0.0752103283492573,0.40341013740704,0,0,0.327543835020193,0,0,0,0,0,0,0,0,0,0.255524855279191,0,0,0,0,0.0887023701626388,0,0.171488009437418,0,0,0,0,0,0,0,0,0.215927591218621,0,0,0,0,0,3.20684545892101,0,0.17071847709395,0,0,0,0,0,0.22910686854405,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0771741581079447,0,0,0,0,0,0,0,4.41810498188324,0.0939839179798536,0.0644578879735772,0,0,0.352894871715692,0,0,0,0,0,0,0,0,1.48798007266701,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0620747142958579,0.112131862580613,0.0636471582781649,0,0,0,0,0.358611026963382,0,0.0814032686109745,0,1.9307228228694,0,0,0,0,0.665756774185513,0,0 | |phase1_expression=1.99846217197612,4.06790995392868,0.563817616383885,4.00293193412522,1.78784437770915,2.61701557230111,0,0.631719873426831,0.261185628199839,0.245733936501509,0,0.436882744260345,0.263766978228454,0,0,0,0,0,0,0,0,0,0,0,0.125542639594803,0,0,0,0,0,0,0,0,0,0,0,0,0,1.00272223735071,0,0,0.32389366601898,0,0,0,0,0.697287110717054,0,0,2.01384674625505,0,0.236482229888585,1.37898272294647,0.645484683583826,0,0.564727018627814,0,0.224723484445085,1.22433556948361,0,0,0,0,0,3.19230162491442,0.56738522469114,0.622822248995575,0.75374599577023,0,0,0.605399502633369,0,0,0,0,0,0,0.300353785683013,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.12786256184353,0,1.00267582127178,0.144846518960824,1.5905718941022,0.973269740605272,0,0,0,0,0,0,0,0,0,0,0,0,1.19257444420023,0,2.08284300964557,2.82653970962005,0,1.37559020970034,0.208994966536811,0,0.71153252537342,0.66944122552934,0.805658634218294,0.760272105718513,0.732186172644509,1.10298924103761,3.24056779152704,0.535798369704479,0.898117490504679,1.46394924628319,0,0.949265659568129,0.183201743930407,0,0,0,7.45457927542978,0.633152558322899,0.662045904066094,1.43418310374407,0,0,2.1349799145941,0.49333509683432,0,0.134710672069688,0.163461903113459,0,0,0,0,0,0.149448680551801,0,0,0,0.61246251376468,0,0.103325781175765,3.56400857184616,6.92347401979959,0,0,0,0,0.277064115484183,1.31693286264251,3.0648779579902,3.15499923703853,0.113432183160021,3.04962380671065,2.56268866582281,1.48352330811693,1.20036438433761,1.03052529238439,0.772921620136887,0.744467425326359,0.843881661206331,0.487185025805993,0.252433774244115,0.828449087780694,0.161646056818812,0.710019185033229,0.403008392910561,0.847802961552438,0.193260853163297,0.818238361772504,0.286804595389004,0,0,0,0,0,0,0,1.28648187638577,1.38134921352481,1.39310378409594,1.44375896333917,0.118306800039844,0,0.241011029883482,0,0.217879444092406,0,0,0,0.38474715694639,0,0,0,0,0,0,0,0,0.122988438543114,0,0.219500570817251,1.1240175325762,0.100528972411631,0.185176890317059,0,0,0,0,0.117408694235822,0.721832238805369,0,0.761016608938393,0.790204397959275,0.858486162094873,0,0,0,0.93733833986777,1.51183915378974,0.141775097242386,0.358234090811393,0.290633938513962,0.766765358330422,0,0,0,0,0,0,0,0,0,0.102827492703324,0,0,0.112131084345361,0,0.07333828582095,0,0,0.845302752556,0,1.04007436911366,0,0,0,0.142977993658148,0,0,0,0,0,0,0,0,0,0,0,0.479249710983165,0,0,0.434343920002738,0.205476322550383,0.358121926479791,0,0,0,0,0,0,0,0,0,0,0,0,0.12269149171914,0,0,1.66376689224646,1.60586089917446,1.89242898040722,1.17141414992713,0.300946099727719,0,0,0,0.184369168541703,0.347534457872331,0,0,0,0,0,0.606255142892519,0,0,1.98486246255021,3.6830873589135,4.49056151092918,0.640695746278505,2.55853624533352,2.73451665944133,0,0.308419387605311,0.177561725313127,0.164254312027618,0,0,0,0.601519410909855,0,0.34444334449382,0.364182336013434,0,0,0,0,0,0,0,0.170093705276516,0,4.62681758070868,0,0,0.254876273045038,0,0,0,0,0,0,0,0,0.0915694648183434,0,0,2.60024098414608,1.6068392984416,0,0,0,0.137836572484531,0,0,0,0,0.661139661443912,1.15314040419064,2.55225424989168,0.50578890427775,0,0,0,0,0,0.869932992075073,0.9266210955196,0.143124886741991,0,0,0.190630193923825,0,0,0,0,0.179872457583315,0.274537029736055,0,0,0,0,0.48763373908959,0.243713489631284,2.11300293513511,0,0.282810863907425,0,0,0.66343897524122,0.876901770507525,0,0,1.01455188481352,0.6196469961995,0,0,0.294747123039363,0.35667105148125,0,0,0,0,0.349934720244983,0,0,0,0,0.86101074534246,1.68471475667626,0,0.689170200620878,0,0,0,0,0,0,0,0,0,1.92495971052672,0,0,0,0,0,0,0,0,0,0,0,0,0,0.169291777801603,0,0,0,0,0,0,0,0,0,0,0.270455678475983,0,0,0,0,0,0,0,1.67121139316383,0.593929361665277,2.45728561679386,0,0,0,0,0,0,0,0,0,0,1.55519793830904,0.629078458031288,0,0,0.197286811273867,0,2.22273980289274,0,0,0,0.260427761085233,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.227884111694002,0,0,0,0.31900115973192,1.00757352742049,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0884575645033392,0,0,0,0,0,0,0,0,0,0,0,0,0,0.126373159256976,0,0,0,0,0,0,0,0,0,0.0979923974143777,0.0870592065804026,0.17472666824203,0,0,0,0,0,0,0,0,0,0,0,0.801588202515337,0,0,0,0,0,0,0,0.235694034616795,0,0,0.407992870545287,0,0,0,0,1.28929632425987,0,0.279282401272254,0,0,0,0,0,0,8.28689732147528,0,0.0787831823072236,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.104909176269996,0,0,0.191915197319445,0,0,0,0,0,0,0,0,1.87426823963964,0,0,0,0,0,0.171086837884329,0,0.640724475406168,0.157204305099666,0,0,0,0,0,0,0,0.306345576763462,0,0,0,0,0,0,0,0,0,0.124980407962107,0,0,0,0.468334905806882,0,0.149254802886874,0,0.554805861502613,0,0,0,0,0,0.15543720058278,0,0.159296767163702,0,0.465788870628778,0,0.53168342911599,0,0,0.380805212168795,0,0.181848659202559,0.107410557042488,0.464033759878494,0.398095888698616,2.40016658797892,0,0.336749488765919,0,0,0,0,1.58694147858591,0.231522474323834,0.489473409012935,0.358177682162975,0,0,0,0,0,0.76872455576384,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2.22603045457393,0,0,0.352675943690684,0.918736432059601,0,0,0,0,0,0,0,0,0.0981477185010256,0,0,0.231051332300676,0.381382095467167,0,0,0.0752103283492573,0.40341013740704,0,0,0.327543835020193,0,0,0,0,0,0,0,0,0,0.255524855279191,0,0,0,0,0.0887023701626388,0,0.171488009437418,0,0,0,0,0,0,0,0,0.215927591218621,0,0,0,0,0,3.20684545892101,0,0.17071847709395,0,0,0,0,0,0.22910686854405,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0771741581079447,0,0,0,0,0,0,0,4.41810498188324,0.0939839179798536,0.0644578879735772,0,0,0.352894871715692,0,0,0,0,0,0,0,0,1.48798007266701,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0620747142958579,0.112131862580613,0.0636471582781649,0,0,0,0,0.358611026963382,0,0.0814032686109745,0,1.9307228228694,0,0,0,0,0.665756774185513,0,0 | ||
|short_description=p37@THBS1 | |||
}} | }} |
Latest revision as of 11:06, 17 September 2015
Short description: | p37@THBS1 |
---|---|
Species: | Human (Homo sapiens) |
DPI dataset: | Robust |
TSS-like-by-RIKEN-classifier(Yes/No): | Yes |
DHS support(Yes/No): | Yes |
Description: | CAGE_peak_37_at_THBS1_5end |
Coexpression cluster: | C453_hepatic_Ewing_neurofibroma_spindle_tridermal_Olfactory_bone |
Association with transcript: | 279bp_to_ENST00000560894_5end |
EntrezGene: | THBS1 |
HGNC: | 11785 |
UniProt: | NA |
Genome view: | ZENBU |
View on UCSC genome browser
CAGE Expression
- Click each plot point to find sample in table
Ontology-based sample term enrichment analysis<b>Summary:</b>This analysis has been performed by utilizing wilcoxon rank sum test.When the number of associated cells/tissues are > n , randomly sampled n cells/tissues are used for P value calculation with rank sum test. this process are repeated several times, and the P values are averaged on the log space <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source dataset<br>data
Ontology term | p-value | n |
---|---|---|
aortic endothelial cell | 7.27e-12 | 6 |
endothelial cell of artery | 7.92e-11 | 9 |
preadipocyte of the breast | 4.41e-10 | 3 |
fibroblast | 3.35e-09 | 76 |
hair follicle cell | 8.73e-09 | 5 |
receptor cell | 1.37e-07 | 6 |
sensory epithelial cell | 1.37e-07 | 6 |
olfactory epithelial cell | 1.37e-07 | 6 |
adipocyte of breast | 3.60e-07 | 2 |
blood vessel endothelial cell | 9.85e-07 | 18 |
embryonic blood vessel endothelial progenitor cell | 9.85e-07 | 18 |
Ontology term | p-value | n |
---|---|---|
endothelial tube | 7.92e-11 | 9 |
arterial system endothelium | 7.92e-11 | 9 |
endothelium of artery | 7.92e-11 | 9 |
hair follicle | 8.73e-09 | 5 |
hair follicle placode | 8.73e-09 | 5 |
omentum | 2.28e-08 | 6 |
peritoneum | 2.28e-08 | 6 |
abdominal cavity | 2.28e-08 | 6 |
visceral peritoneum | 2.28e-08 | 6 |
breast | 1.47e-07 | 10 |
skin of body | 4.48e-07 | 41 |
simple squamous epithelium | 6.61e-07 | 22 |
chest | 7.88e-07 | 11 |
blood vessel endothelium | 9.85e-07 | 18 |
endothelium | 9.85e-07 | 18 |
cardiovascular system endothelium | 9.85e-07 | 18 |
Ontology term | p-value | n |
---|---|---|
musculoskeletal system disease | 5.92e-14 | 5 |
myotonic disease | 5.92e-14 | 5 |
muscle tissue disease | 5.92e-14 | 5 |
myopathy | 5.92e-14 | 5 |
muscular disease | 5.92e-14 | 5 |
myotonic dystrophy | 5.92e-14 | 5 |
teratoma | 4.43e-07 | 2 |