MCL coexpression mm9:505: Difference between revisions
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{{MCL_coexpression_mm9| | {{MCL_coexpression_mm9|coexpression_dpi_cluster_scores_mean=0.0396986551919192,0.149714746110228,0.166351840940158,0.0907368856858658,0.111462990460243,0.062547194911189,0.0704520322075767,0.260673823207834,0.87885582697652,0.968527601481837,0.172756479804208,0.171067960349606,0.219060834193191,0.203114888274405,-0.00151910874079151,0.0540635149318099,0.0242421637662957,0.115740126156036,0.102667902991739,0.0915824837858381,0.0472368922369731,0.0158780503753909,0.0355138234465083,0.0294528342089963,0.038712208450445,0.0917430548793829,0.0573153947933157,0.0907271600479343,0.0597824564021127,0.0719609250316633,0.0489834753112744,0.00607416102245014,-0.00448638507286471,-0.0193570956829275,0.0184024816235049,-0.00203553948444425,0.0516227223381785,0.046433137384507,0.0360009569916934,0.0360520541031495,0.0191189818722848,0.0643636256150284,0.0486800615951405,0.00433036259312779,0.0177190287315917,0.000797836871775779,0.0165004849566631,0.0235580014881924,0.0125260459908882,0.0120456290573029,0.0238473332073066,0.00828213241202526,0.368851660808342,0.980030253996513,0.582559170027884,0.0219267832104592,-0.011541304325977,0.0155278164062167,0.00107297504266267,-0.00618531545628534,-0.00412800716289506,0.007799364868854,0.000378599199086,0.0385803131864135,0.0446298191721619,-0.00270580784766921,0.0150987714611279,0.000814988343401501,0.00278153336927898,0.00959782966282931,-0.00751395423581728,0.0242690102254153,0.0157221860119896,-0.00247965649361505,0.0126126046965161,-0.0193570956829275,0.0628130587479625,-0.00556921298900534,0.0131792231571188,-0.00237160606962406,0.0131853731407634,-0.00634963297916168,-0.00408099871436165,-0.00550759483014221,0.00867201053481594,0.000289658784482293,0.0134309766272184,0.00637859898469624,0.0619848770386552,-0.00397846685876893,0.170435055570053,0.0502091936537891,0.0578618058267122,0.00741962003421907,0.0220049388728393,0.0318198990641458,0.00775779362482014,-0.000494611863666664,-0.00502898435242779,-0.0193570956829275,0.0499812508432808,0.00625406692310452,0.0199279060883598,-0.0193570956829275,0.0718905024271675,0.0708602378072662,0.0925759734589548,0.0458458774764454,0.167955377132996,0.0586960705409419,0.00477084178328877,-0.0111119106604422,-0.00648246998328782,0.00134451031974002,0.0131294753299569,0.00634779274202989,0.0205144281336397,0.0131610269896021,0.0318985651074395,0.0196837389448691,0.0436470368296728,0.0608822267268582,-0.0193570956829275,0.0188398896764664,0.0313983876674617,0.0621711459750682,0.129996603495522,0.0243772428312534,0.0672759588942364,0.0170732095191604,0.0245997292181304,-0.00544788631565713,0.00857672920901509,0.0195355271860086,0.0230909835577263,0.0288065243566172,0.00335450266610382,0.0463594138917358,0.0429059764012773,0.0569421443876633,0.00882005732637701,-9.91218372616476e-05,0.0392778706728083,0.0134505229153755,0.0202407030614094,0.022976261830852,0.0281030396196619,0.034942584082359,0.00387429106823918,0.0134404842650947,0.0124980655878218,-0.00706089085013956,-0.0117466021168847,0.0213703222458435,0.0136385476330404,0.00642833723707842,-0.00285609920148657,0.0438938430828543,0.0649833316660484,0.0223052779567441,0.00564559919371645,0.0233957619093909,0.0244667818213847,0.00208097898273475,0.0260800939671847,-0.00638582584667597,0.0146646522434908,0.0162868881528422,0.00871879482878353,0.0113038717046034,0.0193953853290062,0.0332124696828442,0.0322603680852442,0.0082901252627737,0.0083443868672058,-0.0105130560423914,0.130262154684587,0.0192105276590701,0.00798119108688054,-0.0193570956829275,0.00844217539962734,0.00344007772536462,0.00661113540880671,-0.0139550030692074,0.0497911765269098,0.0113901269705836,0.0176620745559966,0.0490307176176485,0.0267740486465519,0.0204262846286007,0.0496794721396462,0.0479018505998017,-0.00858198942307959,-0.00593364910386493,-0.0193570956829275,0.00364310411078338,0.00180960584918949,0.0136226776056335,0.035867988845891,0.0283846358836697,0.0217506082116574,0.0454065795611981,-0.011303049104635,-0.00198142207484624,0.00187703358317157,-0.0015447673127743,0.0367608756817823,0.0149975975249264,0.000448326227088998,0.00258591178318226,0.0218193642983386,0.0480245010927134,0.0503064455548494,0.0273438219984319,0.0227665847838854,0.00729948922964036,0.0222896052695048,0.0172810806998248,0.0701212343469616,-0.0193570956829275,0.0111084688870679,0.00313857581168715,0.00371759279492918,-0.00143061897562734,0.0192183224183578,0.0471006203750558,0.033304664904659,0.0319470564384743,0.0344243875412042,0.0403921642718025,0.0190369293779178,0.0367496953994522,0.00916522137749086,0.0510787252102327,0.0178643761340945,0.0305857661244168,-0.0107188042213119,0.024673651352615,-0.00114188580542633,0.00728969203011975,-0.00234372911977953,0.0266729006874967,0.00386064148215785,-0.0193570956829275,0.00455413725604955,-0.0054403668404386,-0.00881296661317752,-0.011403630715792,0.0116422878962005,0.0200782344486598,0.00811705093905051,0.018620848146428,0.0267174402599407,0.0437871553058109,0.0330544211822839,0.01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regulation of interleukin-1 secretion;0.0132424415555956;15978!GO:0050706;regulation of interleukin-1 beta secretion;0.0132424415555956;15978!GO:0005133;interferon-gamma receptor binding;0.0132424415555956;15978!GO:0050702;interleukin-1 beta secretion;0.0132424415555956;15978!GO:0050718;positive regulation of interleukin-1 beta secretion;0.0132424415555956;15978!GO:0050704;regulation of interleukin-1 secretion;0.0132424415555956;15978!GO:0050701;interleukin-1 secretion;0.0132424415555956;15978!GO:0050715;positive regulation of cytokine secretion;0.0154473990081625;15978!GO:0031641;regulation of myelination;0.0154473990081625;15978!GO:0001781;neutrophil apoptosis;0.0154473990081625;15978!GO:0031642;negative regulation of myelination;0.0154473990081625;15978!GO:0006925;inflammatory cell apoptosis;0.0154473990081625;15978!GO:0045348;positive regulation of MHC class II biosynthetic process;0.0213857767070597;15978!GO:0045342;MHC class II biosynthetic process;0.021790176931256;15978!GO:0045346;regulation of MHC class II biosynthetic process;0.021790176931256;15978!GO:0001780;neutrophil homeostasis;0.021790176931256;15978!GO:0050714;positive regulation of protein secretion;0.021790176931256;15978!GO:0045084;positive regulation of interleukin-12 biosynthetic process;0.021790176931256;15978!GO:0031645;negative regulation of neurological process;0.021790176931256;15978!GO:0050707;regulation of cytokine secretion;0.021790176931256;15978!GO:0045080;positive regulation of chemokine biosynthetic process;0.021790176931256;15978!GO:0045410;positive regulation of interleukin-6 biosynthetic process;0.021790176931256;15978!GO:0050663;cytokine secretion;0.021790176931256;15978!GO:0048304;positive regulation of isotype switching to IgG isotypes;0.021790176931256;15978!GO:0045075;regulation of interleukin-12 biosynthetic process;0.021790176931256;15978!GO:0042090;interleukin-12 biosynthetic process;0.021790176931256;15978!GO:0045073;regulation of chemokine biosynthetic process;0.021790176931256;15978!GO:0050755;chemokine metabolic process;0.021790176931256;15978!GO:0042033;chemokine biosynthetic process;0.021790176931256;15978!GO:0045893;positive regulation of transcription, DNA-dependent;0.021790176931256;17355,15978!GO:0032602;chemokine production;0.021790176931256;15978!GO:0002262;myeloid cell homeostasis;0.021790176931256;15978!GO:0048302;regulation of isotype switching to IgG isotypes;0.021790176931256;15978!GO:0048291;isotype switching to IgG isotypes;0.021790176931256;15978!GO:0045830;positive regulation of isotype switching;0.0231488920247131;15978!GO:0045408;regulation of interleukin-6 biosynthetic process;0.0231488920247131;15978!GO:0051047;positive regulation of secretion;0.0243639173930027;15978!GO:0042226;interleukin-6 biosynthetic process;0.0243639173930027;15978!GO:0045941;positive regulation of transcription;0.024588616002105;17355,15978!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0249884364350635;17355,15978!GO:0030593;neutrophil chemotaxis;0.0252429620842483;15978!GO:0032615;interleukin-12 production;0.0252429620842483;15978!GO:0045191;regulation of isotype switching;0.0252429620842483;15978!GO:0030968;unfolded protein response;0.0252429620842483;15978!GO:0050708;regulation of protein secretion;0.0287877882763368;15978!GO:0031325;positive regulation of cellular metabolic process;0.031491687820385;17355,15978!GO:0032635;interleukin-6 production;0.031491687820385;15978!GO:0009893;positive regulation of metabolic process;0.0338567739381659;17355,15978!GO:0006984;ER-nuclear signaling pathway;0.0339727947245004;15978!GO:0030595;leukocyte chemotaxis;0.0351381559381551;15978!GO:0002208;somatic diversification of immunoglobulins during immune response;0.0366285591008257;15978!GO:0002204;somatic recombination of immunoglobulin genes during immune response;0.0366285591008257;15978!GO:0045190;isotype switching;0.0366285591008257;15978!GO:0002381;immunoglobulin production during immune response;0.037657011545733;15978!GO:0000082;G1/S transition of mitotic cell cycle;0.0399153947925838;56696!GO:0050871;positive regulation of B cell activation;0.0399153947925838;15978!GO:0031644;regulation of neurological process;0.0399153947925838;15978!GO:0001776;leukocyte homeostasis;0.0399153947925838;15978!GO:0016447;somatic recombination of immunoglobulin gene segments;0.0399153947925838;15978!GO:0042552;myelination;0.0399153947925838;15978!GO:0006402;mRNA catabolic process;0.0399153947925838;387609!GO:0048872;homeostasis of number of cells;0.0399153947925838;15978!GO:0007272;ensheathment of neurons;0.0399153947925838;15978!GO:0016444;somatic cell DNA recombination;0.0399153947925838;15978!GO:0008366;axon ensheathment;0.0399153947925838;15978!GO:0002562;somatic diversification of immune receptors via germline recombination within a single locus;0.0399153947925838;15978!GO:0009306;protein secretion;0.0399153947925838;15978!GO:0016445;somatic diversification of immunoglobulins;0.0399153947925838;15978!GO:0006986;response to unfolded protein;0.0399153947925838;15978!GO:0050900;leukocyte migration;0.0399153947925838;15978!GO:0051789;response to protein stimulus;0.0399153947925838;15978!GO:0002200;somatic diversification of immune receptors;0.0399153947925838;15978!GO:0006401;RNA catabolic process;0.0399153947925838;387609!GO:0042108;positive regulation of cytokine biosynthetic process;0.0399153947925838;15978!GO:0001608;nucleotide receptor activity, G-protein coupled;0.0421348562320759;56696!GO:0045028;purinergic nucleotide receptor activity, G-protein coupled;0.0421348562320759;56696!GO:0016502;nucleotide receptor activity;0.0421348562320759;56696!GO:0001614;purinergic nucleotide receptor activity;0.0421348562320759;56696!GO:0001508;regulation of action potential;0.0421348562320759;15978!GO:0005351;sugar:hydrogen ion symporter activity;0.0421348562320759;72144!GO:0050864;regulation of B cell activation;0.0421348562320759;15978!GO:0051119;sugar transmembrane transporter activity;0.0423108307625072;72144!GO:0005126;hematopoietin/interferon-class (D200-domain) cytokine receptor binding;0.0423108307625072;15978!GO:0002377;immunoglobulin production;0.0423108307625072;15978!GO:0015144;carbohydrate transmembrane transporter activity;0.0423108307625072;72144!GO:0002440;production of molecular mediator of immune response;0.042392315721844;15978!GO:0045727;positive regulation of translation;0.042392315721844;15978!GO:0051325;interphase;0.0424698555447445;56696!GO:0051329;interphase of mitotic cell cycle;0.0424698555447445;56696!GO:0031328;positive regulation of cellular biosynthetic process;0.0440345887227541;15978!GO:0006355;regulation of transcription, DNA-dependent;0.0469885842929266;17355,387609,15978!GO:0006351;transcription, DNA-dependent;0.0478399343710492;17355,387609,15978!GO:0032774;RNA biosynthetic process;0.0478399343710492;17355,387609,15978!GO:0009615;response to virus;0.0480042215885874;15978!GO:0042035;regulation of cytokine biosynthetic process;0.0484616437683431;15978!GO:0051046;regulation of secretion;0.0494937473468433;15978!GO:0045449;regulation of transcription;0.0494937473468433;17355,387609,15978!GO:0009891;positive regulation of biosynthetic process;0.0497763615691983;15978!|ontology_enrichment_celltype=CL:0000791!2.01e-22!9;CL:0000789!2.01e-22!9;CL:0002420!2.01e-22!9;CL:0002419!2.01e-22!9;CL:0000790!2.01e-22!9;CL:0000838!2.97e-20!12;CL:0000624!4.83e-20!8;CL:0000542!1.61e-18!13;CL:0000051!1.61e-18!13;CL:0000084!5.44e-18!11;CL:0000827!5.44e-18!11;CL:0000893!2.64e-15!6;CL:0002489!2.64e-15!6;CL:0000898!2.64e-15!6;CL:0000809!2.64e-15!6;CL:0000810!2.64e-15!6;CL:0000895!2.64e-15!6;CL:0000808!2.64e-15!6;CL:0000894!2.64e-15!6;CL:0000806!2.64e-15!6;CL:0000807!2.64e-15!6;CL:0000805!2.64e-15!6;CL:0002425!2.64e-15!6;CL:0002436!2.64e-15!6;CL:0002427!2.64e-15!6;CL:0002428!2.64e-15!6;CL:0002429!2.64e-15!6;CL:0002433!2.64e-15!6;CL:0002431!2.64e-15!6;CL:0002432!2.64e-15!6;CL:0002242!1.29e-14!16;CL:0000738!1.27e-13!17;CL:0002087!1.27e-13!17;CL:0000988!2.58e-12!32;CL:0002032!2.58e-12!32;CL:0000037!2.58e-12!32;CL:0000566!2.58e-12!32;CL:0000837!2.58e-12!32;CL:0002031!3.05e-12!25;CL:0002320!7.68e-09!46;CL:0000134!7.68e-09!46;CL:0000219!4.39e-08!54|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0002370!1.45e-22!23;UBERON:0000974!1.45e-22!23;UBERON:0004807!1.45e-22!23;UBERON:0005058!1.45e-22!23;UBERON:0003351!1.45e-22!23;UBERON:0009113!1.45e-22!23;UBERON:0003295!1.45e-22!23;UBERON:0009722!1.45e-22!23;UBERON:0005562!1.45e-22!23;UBERON:0007690!1.45e-22!23;UBERON:0006562!1.84e-21!24;UBERON:0003408!1.84e-21!24;UBERON:0001557!1.84e-21!24;UBERON:0001042!1.84e-21!24;UBERON:0008814!1.84e-21!24;UBERON:0009145!1.84e-21!24;UBERON:0004177!2.89e-19!29;UBERON:0005057!2.89e-19!29;UBERON:0000072!1.20e-18!27;UBERON:0000077!2.19e-17!35;UBERON:0002193!1.20e-14!48;UBERON:0002405!1.20e-14!48;UBERON:0002390!3.88e-14!45;UBERON:0003061!3.88e-14!45;UBERON:0000063!1.65e-13!35;UBERON:0007811!5.00e-13!36;UBERON:0000065!5.56e-11!41;UBERON:0001004!1.24e-10!42;UBERON:0000153!2.68e-10!43;UBERON:0003929!1.30e-09!55;UBERON:0002384!7.68e-09!46;UBERON:0002368!2.14e-07!60;UBERON:0000490!2.49e-07!66;UBERON:0005911!7.74e-07!69;UBERON:0003081!8.14e-07!87|tfbs_overrepresentation_for_novel_motifs=0.6379,0.0679776,0.589984,0.25808,0.391122,0.269875,0.346405,0.0669598,0.536572,0.236908,0.831817,0.336042,0.511203,0.357027,0.419678,0,1.31449,0.377686,0.0594359,0.100162,0.176628,0.329508,0.356242,0.388504,1.13761,0.381085,0.448115,0.287195,0.154744,0.338204,0.275529,0.624931,0.117091,0.702925,0.420513,0.0302663,0.725394,0.332941,0.097604,0.0808072,0.77022,0.76591,0.145909,0.136236,0.486712,0.24907,0.457618,0.300372,0.112678,0.156829,0.514446,1.04423,0.321327,0.759566,0.776306,1.69768,0.163199,1.56359,0.0511827,0.36147,0.606104,1.06252,0.0784106,1.25819,0.372973,0.541429,0.908031,1.25063,0.60172,1.10561,0.555733,0.526777,0.0681764,0.808562,0.407198,0.37844,0.396955,0.447339,0.590017,0.179738,0.247973,0.546623,0.411949,0.849185,0.69807,0.0177525,0.0223411,0.145915,0.462057,1.41118,0.975915,0.702809,0.636995,0.799202,0.0951738,2.68649,0.503836,0.639644,0.457849,0.529405,0.111186,1.51291,0.742871,0.514993,1.27935,0.279432,0.569344,0.804983,0.539826,0.177945,1.17217,0.744577,0.533113,0.841652,0.982794,0.119923,0.189757,0.26114,0.53175,1.72347,0.813766,0.484912,0.382687,0.446521,1.03573,0.593478,0.353461,0.630607,0.906557,0.406303,0.726634,0.252176,0.877862,0.375176,1.0039,0.162091,0.231086,0.280962,0.955897,1.77738,1.3796,0.91261,1.01903,0.634793,2.18763,0.280171,0.460443,1.73788,0.232952,0.787076,0.3445,0.144255,0.761071,1.53499,0.374365,0.839715,0.405736,0.866018,0.222538,0.230865,0.96517,0.697256,0.593895,0.21719,0.50503,1.71381,0.110426,0.33468,0.134465|tfbs_overrepresentation_jaspar=MA0003.1;0.0100854,MA0004.1;0.258473,MA0006.1;0.1319,MA0007.1;0.246385,MA0009.1;0.649874,MA0014.1;0.0625332,MA0017.1;0.458117,MA0019.1;0.480432,MA0024.1;0.608636,MA0025.1;0.873493,MA0027.1;2.275,MA0028.1;0.430035,MA0029.1;0.588275,MA0030.1;1.44943,MA0031.1;0.561217,MA0038.1;0.381016,MA0040.1;0.661716,MA0041.1;0.198922,MA0042.1;0.553522,MA0043.1;0.74191,MA0046.1;0.683926,MA0048.1;0.534002,MA0050.1;1.43876,MA0051.1;1.78642,MA0052.1;0.669354,MA0055.1;0.45021,MA0056.1;0,MA0057.1;0.489127,MA0058.1;0.541281,MA0059.1;0.19314,MA0060.1;0.0819399,MA0061.1;2.89705,MA0063.1;0,MA0066.1;0.371389,MA0067.1;0.981551,MA0068.1;6.50096,MA0069.1;0.669676,MA0070.1;0.660488,MA0071.1;0.289658,MA0072.1;0.652465,MA0073.1;18.7148,MA0074.1;0.340281,MA0076.1;0.952244,MA0077.1;0.632005,MA0078.1;0.418168,MA0081.1;0.210747,MA0083.1;0.741151,MA0084.1;1.30392,MA0087.1;0.699999,MA0088.1;0.171343,MA0089.1;0,MA0090.1;0.231074,MA0091.1;0.741628,MA0092.1;0.231323,MA0093.1;0.444403,MA0095.1;0,MA0098.1;0,MA0100.1;0.330364,MA0101.1;1.72541,MA0103.1;0.927638,MA0105.1;1.05934,MA0106.1;0.425111,MA0107.1;2.80186,MA0108.2;0.50131,MA0109.1;0,MA0111.1;0.242308,MA0113.1;0.400008,MA0114.1;1.10492,MA0115.1;0.744589,MA0116.1;0.131762,MA0117.1;0.713754,MA0119.1;0.200349,MA0122.1;0.732707,MA0124.1;0.929684,MA0125.1;0.857794,MA0130.1;0,MA0131.1;1.19873,MA0132.1;0,MA0133.1;0,MA0135.1;0.77683,MA0136.1;0.940193,MA0139.1;0.231431,MA0140.1;0.330266,MA0141.1;0.511953,MA0142.1;0.547747,MA0143.1;0.414534,MA0144.1;0.100037,MA0145.1;0.189432,MA0146.1;0.170737,MA0147.1;0.107632,MA0148.1;0.271704,MA0149.1;0.204102,MA0062.2;0.39919,MA0035.2;0.33429,MA0039.2;0.753752,MA0138.2;0.469076,MA0002.2;0.5079,MA0137.2;0.169785,MA0104.2;0.0740839,MA0047.2;0.380343,MA0112.2;0.189423,MA0065.2;0.371748,MA0150.1;0.246295,MA0151.1;0,MA0152.1;0.380437,MA0153.1;0.792819,MA0154.1;0.0285118,MA0155.1;0.0879017,MA0156.1;0.949678,MA0157.1;0.518122,MA0158.1;0,MA0159.1;0.365914,MA0160.1;0.753068,MA0161.1;0,MA0162.1;0.108524,MA0163.1;0.0388292,MA0164.1;0.357779,MA0080.2;0.912084,MA0018.2;0.366212,MA0099.2;0.463355,MA0079.2;1.43677,MA0102.2;1.35579,MA0258.1;0.0900907,MA0259.1;0.101001,MA0442.1;0}} | ||
Latest revision as of 15:25, 17 September 2013
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr10:117878100..117878106,+ | p1@Ifng |
| Mm9::chr12:114099183..114099192,- | p2@Gpr132 |
| Mm9::chr15:57526415..57526425,+ | p7@Zhx2 |
| Mm9::chr19:53608314..53608329,+ | p@chr19:53608314..53608329 + |
| Mm9::chr19:53608416..53608432,+ | p@chr19:53608416..53608432 + |
| Mm9::chr5:104182581..104182598,+ | p@chr5:104182581..104182598 + |
| Mm9::chr5:104182694..104182724,+ | p8@Aff1 |
| Mm9::chr5:104182725..104182737,+ | p17@Aff1 |
| Mm9::chr5:115938931..115938941,- | p@chr5:115938931..115938941 - |
| Mm9::chr6:39327613..39327630,- | p3@Slc37a3 |
| Mm9::chr6:48687331..48687339,+ | p@chr6:48687331..48687339 + |
| Mm9::chr7:16531372..16531383,- | p4@Gltscr2 |
| Mm9::chr9:120019615..120019626,+ | p5@Slc25a38 |
| Mm9::chrX:75691974..75691976,+ | p@chrX:75691974..75691976 + |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0050716 | positive regulation of interleukin-1 secretion | 0.0132424415555956 |
| GO:0050706 | regulation of interleukin-1 beta secretion | 0.0132424415555956 |
| GO:0005133 | interferon-gamma receptor binding | 0.0132424415555956 |
| GO:0050702 | interleukin-1 beta secretion | 0.0132424415555956 |
| GO:0050718 | positive regulation of interleukin-1 beta secretion | 0.0132424415555956 |
| GO:0050704 | regulation of interleukin-1 secretion | 0.0132424415555956 |
| GO:0050701 | interleukin-1 secretion | 0.0132424415555956 |
| GO:0050715 | positive regulation of cytokine secretion | 0.0154473990081625 |
| GO:0031641 | regulation of myelination | 0.0154473990081625 |
| GO:0001781 | neutrophil apoptosis | 0.0154473990081625 |
| GO:0031642 | negative regulation of myelination | 0.0154473990081625 |
| GO:0006925 | inflammatory cell apoptosis | 0.0154473990081625 |
| GO:0045348 | positive regulation of MHC class II biosynthetic process | 0.0213857767070597 |
| GO:0045342 | MHC class II biosynthetic process | 0.021790176931256 |
| GO:0045346 | regulation of MHC class II biosynthetic process | 0.021790176931256 |
| GO:0001780 | neutrophil homeostasis | 0.021790176931256 |
| GO:0050714 | positive regulation of protein secretion | 0.021790176931256 |
| GO:0045084 | positive regulation of interleukin-12 biosynthetic process | 0.021790176931256 |
| GO:0031645 | negative regulation of neurological process | 0.021790176931256 |
| GO:0050707 | regulation of cytokine secretion | 0.021790176931256 |
| GO:0045080 | positive regulation of chemokine biosynthetic process | 0.021790176931256 |
| GO:0045410 | positive regulation of interleukin-6 biosynthetic process | 0.021790176931256 |
| GO:0050663 | cytokine secretion | 0.021790176931256 |
| GO:0048304 | positive regulation of isotype switching to IgG isotypes | 0.021790176931256 |
| GO:0045075 | regulation of interleukin-12 biosynthetic process | 0.021790176931256 |
| GO:0042090 | interleukin-12 biosynthetic process | 0.021790176931256 |
| GO:0045073 | regulation of chemokine biosynthetic process | 0.021790176931256 |
| GO:0050755 | chemokine metabolic process | 0.021790176931256 |
| GO:0042033 | chemokine biosynthetic process | 0.021790176931256 |
| GO:0045893 | positive regulation of transcription, DNA-dependent | 0.021790176931256 |
| GO:0032602 | chemokine production | 0.021790176931256 |
| GO:0002262 | myeloid cell homeostasis | 0.021790176931256 |
| GO:0048302 | regulation of isotype switching to IgG isotypes | 0.021790176931256 |
| GO:0048291 | isotype switching to IgG isotypes | 0.021790176931256 |
| GO:0045830 | positive regulation of isotype switching | 0.0231488920247131 |
| GO:0045408 | regulation of interleukin-6 biosynthetic process | 0.0231488920247131 |
| GO:0051047 | positive regulation of secretion | 0.0243639173930027 |
| GO:0042226 | interleukin-6 biosynthetic process | 0.0243639173930027 |
| GO:0045941 | positive regulation of transcription | 0.024588616002105 |
| GO:0045935 | positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0249884364350635 |
| GO:0030593 | neutrophil chemotaxis | 0.0252429620842483 |
| GO:0032615 | interleukin-12 production | 0.0252429620842483 |
| GO:0045191 | regulation of isotype switching | 0.0252429620842483 |
| GO:0030968 | unfolded protein response | 0.0252429620842483 |
| GO:0050708 | regulation of protein secretion | 0.0287877882763368 |
| GO:0031325 | positive regulation of cellular metabolic process | 0.031491687820385 |
| GO:0032635 | interleukin-6 production | 0.031491687820385 |
| GO:0009893 | positive regulation of metabolic process | 0.0338567739381659 |
| GO:0006984 | ER-nuclear signaling pathway | 0.0339727947245004 |
| GO:0030595 | leukocyte chemotaxis | 0.0351381559381551 |
| GO:0002208 | somatic diversification of immunoglobulins during immune response | 0.0366285591008257 |
| GO:0002204 | somatic recombination of immunoglobulin genes during immune response | 0.0366285591008257 |
| GO:0045190 | isotype switching | 0.0366285591008257 |
| GO:0002381 | immunoglobulin production during immune response | 0.037657011545733 |
| GO:0000082 | G1/S transition of mitotic cell cycle | 0.0399153947925838 |
| GO:0050871 | positive regulation of B cell activation | 0.0399153947925838 |
| GO:0031644 | regulation of neurological process | 0.0399153947925838 |
| GO:0001776 | leukocyte homeostasis | 0.0399153947925838 |
| GO:0016447 | somatic recombination of immunoglobulin gene segments | 0.0399153947925838 |
| GO:0042552 | myelination | 0.0399153947925838 |
| GO:0006402 | mRNA catabolic process | 0.0399153947925838 |
| GO:0048872 | homeostasis of number of cells | 0.0399153947925838 |
| GO:0007272 | ensheathment of neurons | 0.0399153947925838 |
| GO:0016444 | somatic cell DNA recombination | 0.0399153947925838 |
| GO:0008366 | axon ensheathment | 0.0399153947925838 |
| GO:0002562 | somatic diversification of immune receptors via germline recombination within a single locus | 0.0399153947925838 |
| GO:0009306 | protein secretion | 0.0399153947925838 |
| GO:0016445 | somatic diversification of immunoglobulins | 0.0399153947925838 |
| GO:0006986 | response to unfolded protein | 0.0399153947925838 |
| GO:0050900 | leukocyte migration | 0.0399153947925838 |
| GO:0051789 | response to protein stimulus | 0.0399153947925838 |
| GO:0002200 | somatic diversification of immune receptors | 0.0399153947925838 |
| GO:0006401 | RNA catabolic process | 0.0399153947925838 |
| GO:0042108 | positive regulation of cytokine biosynthetic process | 0.0399153947925838 |
| GO:0001608 | nucleotide receptor activity, G-protein coupled | 0.0421348562320759 |
| GO:0045028 | purinergic nucleotide receptor activity, G-protein coupled | 0.0421348562320759 |
| GO:0016502 | nucleotide receptor activity | 0.0421348562320759 |
| GO:0001614 | purinergic nucleotide receptor activity | 0.0421348562320759 |
| GO:0001508 | regulation of action potential | 0.0421348562320759 |
| GO:0005351 | sugar:hydrogen ion symporter activity | 0.0421348562320759 |
| GO:0050864 | regulation of B cell activation | 0.0421348562320759 |
| GO:0051119 | sugar transmembrane transporter activity | 0.0423108307625072 |
| GO:0005126 | hematopoietin/interferon-class (D200-domain) cytokine receptor binding | 0.0423108307625072 |
| GO:0002377 | immunoglobulin production | 0.0423108307625072 |
| GO:0015144 | carbohydrate transmembrane transporter activity | 0.0423108307625072 |
| GO:0002440 | production of molecular mediator of immune response | 0.042392315721844 |
| GO:0045727 | positive regulation of translation | 0.042392315721844 |
| GO:0051325 | interphase | 0.0424698555447445 |
| GO:0051329 | interphase of mitotic cell cycle | 0.0424698555447445 |
| GO:0031328 | positive regulation of cellular biosynthetic process | 0.0440345887227541 |
| GO:0006355 | regulation of transcription, DNA-dependent | 0.0469885842929266 |
| GO:0006351 | transcription, DNA-dependent | 0.0478399343710492 |
| GO:0032774 | RNA biosynthetic process | 0.0478399343710492 |
| GO:0009615 | response to virus | 0.0480042215885874 |
| GO:0042035 | regulation of cytokine biosynthetic process | 0.0484616437683431 |
| GO:0051046 | regulation of secretion | 0.0494937473468433 |
| GO:0045449 | regulation of transcription | 0.0494937473468433 |
| GO:0009891 | positive regulation of biosynthetic process | 0.0497763615691983 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.0100854 |
| MA0004.1 | 0.258473 |
| MA0006.1 | 0.1319 |
| MA0007.1 | 0.246385 |
| MA0009.1 | 0.649874 |
| MA0014.1 | 0.0625332 |
| MA0017.1 | 0.458117 |
| MA0019.1 | 0.480432 |
| MA0024.1 | 0.608636 |
| MA0025.1 | 0.873493 |
| MA0027.1 | 2.275 |
| MA0028.1 | 0.430035 |
| MA0029.1 | 0.588275 |
| MA0030.1 | 1.44943 |
| MA0031.1 | 0.561217 |
| MA0038.1 | 0.381016 |
| MA0040.1 | 0.661716 |
| MA0041.1 | 0.198922 |
| MA0042.1 | 0.553522 |
| MA0043.1 | 0.74191 |
| MA0046.1 | 0.683926 |
| MA0048.1 | 0.534002 |
| MA0050.1 | 1.43876 |
| MA0051.1 | 1.78642 |
| MA0052.1 | 0.669354 |
| MA0055.1 | 0.45021 |
| MA0056.1 | 0 |
| MA0057.1 | 0.489127 |
| MA0058.1 | 0.541281 |
| MA0059.1 | 0.19314 |
| MA0060.1 | 0.0819399 |
| MA0061.1 | 2.89705 |
| MA0063.1 | 0 |
| MA0066.1 | 0.371389 |
| MA0067.1 | 0.981551 |
| MA0068.1 | 6.50096 |
| MA0069.1 | 0.669676 |
| MA0070.1 | 0.660488 |
| MA0071.1 | 0.289658 |
| MA0072.1 | 0.652465 |
| MA0073.1 | 18.7148 |
| MA0074.1 | 0.340281 |
| MA0076.1 | 0.952244 |
| MA0077.1 | 0.632005 |
| MA0078.1 | 0.418168 |
| MA0081.1 | 0.210747 |
| MA0083.1 | 0.741151 |
| MA0084.1 | 1.30392 |
| MA0087.1 | 0.699999 |
| MA0088.1 | 0.171343 |
| MA0089.1 | 0 |
| MA0090.1 | 0.231074 |
| MA0091.1 | 0.741628 |
| MA0092.1 | 0.231323 |
| MA0093.1 | 0.444403 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.330364 |
| MA0101.1 | 1.72541 |
| MA0103.1 | 0.927638 |
| MA0105.1 | 1.05934 |
| MA0106.1 | 0.425111 |
| MA0107.1 | 2.80186 |
| MA0108.2 | 0.50131 |
| MA0109.1 | 0 |
| MA0111.1 | 0.242308 |
| MA0113.1 | 0.400008 |
| MA0114.1 | 1.10492 |
| MA0115.1 | 0.744589 |
| MA0116.1 | 0.131762 |
| MA0117.1 | 0.713754 |
| MA0119.1 | 0.200349 |
| MA0122.1 | 0.732707 |
| MA0124.1 | 0.929684 |
| MA0125.1 | 0.857794 |
| MA0130.1 | 0 |
| MA0131.1 | 1.19873 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.77683 |
| MA0136.1 | 0.940193 |
| MA0139.1 | 0.231431 |
| MA0140.1 | 0.330266 |
| MA0141.1 | 0.511953 |
| MA0142.1 | 0.547747 |
| MA0143.1 | 0.414534 |
| MA0144.1 | 0.100037 |
| MA0145.1 | 0.189432 |
| MA0146.1 | 0.170737 |
| MA0147.1 | 0.107632 |
| MA0148.1 | 0.271704 |
| MA0149.1 | 0.204102 |
| MA0062.2 | 0.39919 |
| MA0035.2 | 0.33429 |
| MA0039.2 | 0.753752 |
| MA0138.2 | 0.469076 |
| MA0002.2 | 0.5079 |
| MA0137.2 | 0.169785 |
| MA0104.2 | 0.0740839 |
| MA0047.2 | 0.380343 |
| MA0112.2 | 0.189423 |
| MA0065.2 | 0.371748 |
| MA0150.1 | 0.246295 |
| MA0151.1 | 0 |
| MA0152.1 | 0.380437 |
| MA0153.1 | 0.792819 |
| MA0154.1 | 0.0285118 |
| MA0155.1 | 0.0879017 |
| MA0156.1 | 0.949678 |
| MA0157.1 | 0.518122 |
| MA0158.1 | 0 |
| MA0159.1 | 0.365914 |
| MA0160.1 | 0.753068 |
| MA0161.1 | 0 |
| MA0162.1 | 0.108524 |
| MA0163.1 | 0.0388292 |
| MA0164.1 | 0.357779 |
| MA0080.2 | 0.912084 |
| MA0018.2 | 0.366212 |
| MA0099.2 | 0.463355 |
| MA0079.2 | 1.43677 |
| MA0102.2 | 1.35579 |
| MA0258.1 | 0.0900907 |
| MA0259.1 | 0.101001 |
| MA0442.1 | 0 |
