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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0004503;monophenol monooxygenase activity;0.0101895474352689;22173!GO:0016716;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen;0.0101895474352689;22173!GO:0006583;melanin biosynthetic process from tyrosine;0.0203701635264731;22173!GO:0006582;melanin metabolic process;0.0203701635264731;22173!GO:0042438;melanin biosynthetic process;0.0203701635264731;22173!GO:0006570;tyrosine metabolic process;0.022064049524218;22173!GO:0009072;aromatic amino acid family metabolic process;0.0330725015878092;22173!GO:0046148;pigment biosynthetic process;0.0330725015878092;22173!GO:0042440;pigment metabolic process;0.0350415925669434;22173!GO:0030141;secretory granule;0.0386439563197676;21786!GO:0019748;secondary metabolic process;0.0397424554979222;22173!GO:0005507;copper ion binding;0.0457224475371469;22173!GO:0046982;protein heterodimerization activity;0.0468793886931207;22173!}}
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monooxygenase activity;0.0101895474352689;22173!GO:0016716;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen;0.0101895474352689;22173!GO:0006583;melanin biosynthetic process from tyrosine;0.0203701635264731;22173!GO:0006582;melanin metabolic process;0.0203701635264731;22173!GO:0042438;melanin biosynthetic process;0.0203701635264731;22173!GO:0006570;tyrosine metabolic process;0.022064049524218;22173!GO:0009072;aromatic amino acid family metabolic process;0.0330725015878092;22173!GO:0046148;pigment biosynthetic process;0.0330725015878092;22173!GO:0042440;pigment metabolic process;0.0350415925669434;22173!GO:0030141;secretory granule;0.0386439563197676;21786!GO:0019748;secondary metabolic process;0.0397424554979222;22173!GO:0005507;copper ion binding;0.0457224475371469;22173!GO:0046982;protein heterodimerization activity;0.0468793886931207;22173!|ontology_enrichment_celltype=|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0000970!4.03e-52!9;UBERON:0000019!4.03e-52!9;UBERON:0000047!4.03e-52!9;UBERON:0010312!4.03e-52!9;UBERON:0004088!4.03e-52!9;UBERON:0002104!4.03e-52!9;UBERON:0001456!4.03e-52!9;UBERON:0003072!4.03e-52!9;UBERON:0004128!4.03e-52!9;UBERON:0003071!4.03e-52!9;UBERON:0001444!1.38e-42!11;UBERON:0000020!5.22e-39!12;UBERON:0001032!5.22e-39!12;UBERON:0004456!5.22e-39!12;UBERON:0000033!5.58e-36!13;UBERON:0005085!5.58e-36!13;UBERON:0007811!1.14e-12!36;UBERON:0003056!1.30e-11!49;UBERON:0000153!1.67e-10!43;UBERON:0002346!1.06e-08!64;UBERON:0003075!1.06e-08!64;UBERON:0007284!1.06e-08!64;UBERON:0010371!1.60e-07!73|tfbs_overrepresentation_for_novel_motifs=0.595185,0.0531438,0.548514,0.238864,0.356286,0.250289,0.867472,0.210111,0.0622408,0.0308722,0.288187,0.314655,0.210446,0.335151,0.383709,0,0.505674,1.15495,0.1896,0.409021,0.483972,0.010084,0.334384,0.353775,0.561942,0.35869,2.05391,0.267095,0.851419,0.125189,0.255771,0.598971,0.104128,0.352983,0.384512,0.972588,0.0985485,0.83799,0.606559,0.0703677,0.349739,0.259911,0.0429639,0.122151,0.00110514,0.230148,0.433813,0.279902,0.356013,0.436869,0.48979,0.994193,0.281801,0.732469,0.749094,0.341233,0.452104,0.820802,0.378703,0.339495,0.580338,0.390204,0.516848,0.479581,0.350748,0.516415,0.880067,1.22155,0.576002,1.07689,0.173229,0.218482,0.303663,0.781142,0.040685,0.036326,0.352807,1.08528,0.564426,0.163487,2.30829,2.23206,0.388944,0.443997,0.671442,0.00202775,0.016756,0.297913,0.438181,1.38183,0.947651,0.676142,0.610915,0.365956,0.0836626,0.0741053,0.790304,0.613539,0.43404,1.10823,1.10792,0.59871,0.715894,0.490329,0.489372,0.259558,0.543989,0.276621,0.16693,0.487082,2.45013,0.717588,0.164285,0.292444,0.954503,1.16365,0.694694,0.241826,0.506861,0.096357,0.786314,1.16518,0.360259,0.422901,1.00724,0.567849,0.331666,0.60459,0.8786,0.747079,0.699779,0.233152,0.850049,0.352905,0.975524,0.0491355,2.5333,0.261043,0.927716,1.74768,1.35029,0.884624,0.969317,0.608735,0.483498,0.260275,0.436593,1.7082,0.214583,0.111457,0.303478,0.00817433,0.733963,0.954816,0.928341,0.81211,0.382849,0.403733,0.204546,0.212571,0.93695,0.670634,0.568261,1.09606,0.480505,0.345769,0.323091,0.313326,0.0179486|tfbs_overrepresentation_jaspar=MA0003.1;0.0175753,MA0004.1;0.239244,MA0006.1;1.2381,MA0007.1;0.227553,MA0009.1;0.623671,MA0014.1;0.0468601,MA0017.1;0.832511,MA0019.1;1.15568,MA0024.1;0.582844,MA0025.1;0.845702,MA0027.1;2.24512,MA0028.1;0.12472,MA0029.1;0.562703,MA0030.1;0.568779,MA0031.1;0.535959,MA0038.1;0.358622,MA0040.1;0.635404,MA0041.1;0.18185,MA0042.1;0.172351,MA0043.1;0.71494,MA0046.1;0.657417,MA0048.1;1.11639,MA0050.1;0.743895,MA0051.1;0.366328,MA0052.1;0.642973,MA0055.1;6.84559,MA0056.1;0,MA0057.1;0.431584,MA0058.1;0.167504,MA0059.1;0.176308,MA0060.1;0.071412,MA0061.1;0.295622,MA0063.1;0,MA0066.1;0.921885,MA0067.1;0.953264,MA0068.1;0.446117,MA0069.1;5.11466,MA0070.1;0.634186,MA0071.1;0.269487,MA0072.1;0.626238,MA0073.1;0.983598,MA0074.1;0.318792,MA0076.1;0.148159,MA0077.1;0.605975,MA0078.1;0.395048,MA0081.1;0.193203,MA0083.1;0.714187,MA0084.1;1.27474,MA0087.1;0.673355,MA0088.1;1.07775,MA0089.1;0,MA0090.1;0.212772,MA0091.1;0.696557,MA0092.1;0.213012,MA0093.1;0.130107,MA0095.1;0,MA0098.1;0,MA0100.1;0.309116,MA0101.1;0.538493,MA0103.1;0.439015,MA0105.1;0.0373599,MA0106.1;0.401864,MA0107.1;0.84583,MA0108.2;0.476838,MA0109.1;0,MA0111.1;0.223614,MA0113.1;0.377232,MA0114.1;0.0864402,MA0115.1;0.717599,MA0116.1;0.117928,MA0117.1;0.686999,MA0119.1;0.183219,MA0122.1;0.705806,MA0124.1;0.901619,MA0125.1;0.830088,MA0130.1;0,MA0131.1;0.452196,MA0132.1;0,MA0133.1;0,MA0135.1;0.749615,MA0136.1;0.335579,MA0139.1;0.0558308,MA0140.1;0.30902,MA0141.1;0.155997,MA0142.1;0.522654,MA0143.1;0.391481,MA0144.1;0.296781,MA0145.1;0.0599431,MA0146.1;0.0253534,MA0147.1;0.0952713,MA0148.1;0.252062,MA0149.1;0.18682,MA0062.2;0.0394542,MA0035.2;0.312946,MA0039.2;0.466859,MA0138.2;0.445088,MA0002.2;0.458095,MA0137.2;0.153989,MA0104.2;0.0641853,MA0047.2;0.357963,MA0112.2;0.54155,MA0065.2;0.321967,MA0150.1;0.644946,MA0151.1;0,MA0152.1;0.9415,MA0153.1;0.765498,MA0154.1;0.247047,MA0155.1;0.189024,MA0156.1;0.147567,MA0157.1;0.493416,MA0158.1;0,MA0159.1;0.679844,MA0160.1;0.254455,MA0161.1;0,MA0162.1;0.00143236,MA0163.1;0.0738452,MA0164.1;0.335886,MA0080.2;0.13897,MA0018.2;0.344133,MA0099.2;1.1194,MA0079.2;1.24442,MA0102.2;1.32652,MA0258.1;0.967298,MA0259.1;0.0890842,MA0442.1;0}}

Latest revision as of 15:23, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:28630472..28630482,+p@chr11:28630472..28630482
+
Mm9::chr14:61104032..61104041,+p@chr14:61104032..61104041
+
Mm9::chr1:24237646..24237669,+p@chr1:24237646..24237669
+
Mm9::chr3:128897563..128897574,+p@chr3:128897563..128897574
+
Mm9::chr5:35735487..35735491,+p@chr5:35735487..35735491
+
Mm9::chr6:70906450..70906454,+p1@Foxi3
Mm9::chr6:83660844..83660859,-p1@Vax2os1
Mm9::chr6:97891135..97891147,+p@chr6:97891135..97891147
+
Mm9::chr6:97891166..97891186,+p@chr6:97891166..97891186
+
Mm9::chr6:97891189..97891203,+p@chr6:97891189..97891203
+
Mm9::chr6:97891221..97891223,+p@chr6:97891221..97891223
+
Mm9::chr7:94641837..94641850,-p@chr7:94641837..94641850
-
Mm9::chr8:122025598..122025626,-p1@Slc38a8
Mm9::chr8:122025661..122025666,-p2@Slc38a8
Mm9::chr9:57976869..57976875,+p21@Stra6


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0004503monophenol monooxygenase activity0.0101895474352689
GO:0016716oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen0.0101895474352689
GO:0006583melanin biosynthetic process from tyrosine0.0203701635264731
GO:0006582melanin metabolic process0.0203701635264731
GO:0042438melanin biosynthetic process0.0203701635264731
GO:0006570tyrosine metabolic process0.022064049524218
GO:0009072aromatic amino acid family metabolic process0.0330725015878092
GO:0046148pigment biosynthetic process0.0330725015878092
GO:0042440pigment metabolic process0.0350415925669434
GO:0030141secretory granule0.0386439563197676
GO:0019748secondary metabolic process0.0397424554979222
GO:0005507copper ion binding0.0457224475371469
GO:0046982protein heterodimerization activity0.0468793886931207



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
eye4.03e-529
camera-type eye4.03e-529
simple eye4.03e-529
immature eye4.03e-529
ocular region4.03e-529
visual system4.03e-529
face4.03e-529
optic cup4.03e-529
optic vesicle4.03e-529
eye primordium4.03e-529
subdivision of head1.38e-4211
sense organ5.22e-3912
sensory system5.22e-3912
entire sense organ system5.22e-3912
head5.58e-3613
ectodermal placode5.58e-3613
craniocervical region1.14e-1236
pre-chordal neural plate1.30e-1149
anterior region of body1.67e-1043
neurectoderm1.06e-0864
neural plate1.06e-0864
presumptive neural plate1.06e-0864
ecto-epithelium1.60e-0773


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0175753
MA0004.10.239244
MA0006.11.2381
MA0007.10.227553
MA0009.10.623671
MA0014.10.0468601
MA0017.10.832511
MA0019.11.15568
MA0024.10.582844
MA0025.10.845702
MA0027.12.24512
MA0028.10.12472
MA0029.10.562703
MA0030.10.568779
MA0031.10.535959
MA0038.10.358622
MA0040.10.635404
MA0041.10.18185
MA0042.10.172351
MA0043.10.71494
MA0046.10.657417
MA0048.11.11639
MA0050.10.743895
MA0051.10.366328
MA0052.10.642973
MA0055.16.84559
MA0056.10
MA0057.10.431584
MA0058.10.167504
MA0059.10.176308
MA0060.10.071412
MA0061.10.295622
MA0063.10
MA0066.10.921885
MA0067.10.953264
MA0068.10.446117
MA0069.15.11466
MA0070.10.634186
MA0071.10.269487
MA0072.10.626238
MA0073.10.983598
MA0074.10.318792
MA0076.10.148159
MA0077.10.605975
MA0078.10.395048
MA0081.10.193203
MA0083.10.714187
MA0084.11.27474
MA0087.10.673355
MA0088.11.07775
MA0089.10
MA0090.10.212772
MA0091.10.696557
MA0092.10.213012
MA0093.10.130107
MA0095.10
MA0098.10
MA0100.10.309116
MA0101.10.538493
MA0103.10.439015
MA0105.10.0373599
MA0106.10.401864
MA0107.10.84583
MA0108.20.476838
MA0109.10
MA0111.10.223614
MA0113.10.377232
MA0114.10.0864402
MA0115.10.717599
MA0116.10.117928
MA0117.10.686999
MA0119.10.183219
MA0122.10.705806
MA0124.10.901619
MA0125.10.830088
MA0130.10
MA0131.10.452196
MA0132.10
MA0133.10
MA0135.10.749615
MA0136.10.335579
MA0139.10.0558308
MA0140.10.30902
MA0141.10.155997
MA0142.10.522654
MA0143.10.391481
MA0144.10.296781
MA0145.10.0599431
MA0146.10.0253534
MA0147.10.0952713
MA0148.10.252062
MA0149.10.18682
MA0062.20.0394542
MA0035.20.312946
MA0039.20.466859
MA0138.20.445088
MA0002.20.458095
MA0137.20.153989
MA0104.20.0641853
MA0047.20.357963
MA0112.20.54155
MA0065.20.321967
MA0150.10.644946
MA0151.10
MA0152.10.9415
MA0153.10.765498
MA0154.10.247047
MA0155.10.189024
MA0156.10.147567
MA0157.10.493416
MA0158.10
MA0159.10.679844
MA0160.10.254455
MA0161.10
MA0162.10.00143236
MA0163.10.0738452
MA0164.10.335886
MA0080.20.13897
MA0018.20.344133
MA0099.21.1194
MA0079.21.24442
MA0102.21.32652
MA0258.10.967298
MA0259.10.0890842
MA0442.10
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